U.S. patent application number 15/716544 was filed with the patent office on 2018-03-08 for delivery systems comprising malodor reduction compositions.
The applicant listed for this patent is The Procter & Gamble Company. Invention is credited to Gayle Marie FRANKENBACH, Judith Ann HOLLINGSHEAD, Steven Anthony HORENZIAK, Johan (NMN) SMETS.
Application Number | 20180066210 15/716544 |
Document ID | / |
Family ID | 54256860 |
Filed Date | 2018-03-08 |
United States Patent
Application |
20180066210 |
Kind Code |
A1 |
FRANKENBACH; Gayle Marie ;
et al. |
March 8, 2018 |
DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS
Abstract
The present invention relates to delivery systems comprising
malodor reduction compositions, methods of making such delivery
systems and consumer products made with such delivery systems. Such
delivery systems do not unduely interfere with the scent of the
perfumed or unperfumed delivery system, perfumed or unperfumed
products comprising such delivery systems and any perfumed or
unperfumed situs that is treated with such products.
Inventors: |
FRANKENBACH; Gayle Marie;
(Cincinnati, OH) ; HOLLINGSHEAD; Judith Ann;
(Batavia, OH) ; HORENZIAK; Steven Anthony;
(Cincinnati, OH) ; SMETS; Johan (NMN); (Lubbeek,
BE) |
|
Applicant: |
Name |
City |
State |
Country |
Type |
The Procter & Gamble Company |
Cincinnati |
OH |
US |
|
|
Family ID: |
54256860 |
Appl. No.: |
15/716544 |
Filed: |
September 27, 2017 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
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15421642 |
Feb 1, 2017 |
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15716544 |
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14865412 |
Sep 25, 2015 |
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15421642 |
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62055844 |
Sep 26, 2014 |
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62143862 |
Apr 7, 2015 |
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Current U.S.
Class: |
1/1 |
Current CPC
Class: |
C11D 3/0068 20130101;
C11D 3/184 20130101; G06F 17/11 20130101; A61K 8/11 20130101; A61K
8/35 20130101; G16C 20/40 20190201; A61K 8/31 20130101; A61L 9/03
20130101; A61K 8/8152 20130101; A61L 2209/21 20130101; A61K 8/4973
20130101; A61L 2/18 20130101; C11D 3/2079 20130101; A61K 8/4966
20130101; A61K 8/731 20130101; C11B 9/0042 20130101; A61L 9/012
20130101; C11B 9/0034 20130101; A61K 8/494 20130101; A61K 2800/592
20130101; G16C 10/00 20190201; C11D 3/2034 20130101; C11D 11/0017
20130101; C11D 17/042 20130101; G06F 30/23 20200101; A61Q 19/10
20130101; B01J 20/24 20130101; C11B 9/0015 20130101; C11B 9/003
20130101; C11D 17/06 20130101; A61K 8/4926 20130101; A61Q 15/00
20130101; C11B 9/0092 20130101; C11D 3/2068 20130101; A61L 9/122
20130101; A61L 15/46 20130101; C11D 17/047 20130101; A61L 15/20
20130101; C11D 3/2093 20130101; C11D 3/30 20130101; A61K 8/368
20130101; A61K 2800/5922 20130101; C11B 9/0019 20130101; C11B
9/0038 20130101; C11D 3/505 20130101; G06Q 99/00 20130101; A61K
8/36 20130101; C11B 9/0053 20130101; C11D 3/43 20130101; A61K 8/58
20130101; A61L 2300/62 20130101; C11B 9/0049 20130101; A61Q 5/02
20130101; A61Q 13/00 20130101; A61K 8/37 20130101; C11B 9/008
20130101; C11D 17/0043 20130101; A61K 8/498 20130101; C11D 3/50
20130101; A61K 8/342 20130101; A61L 9/01 20130101; C11D 3/2096
20130101; C11D 3/222 20130101; A61L 15/28 20130101; C11B 9/0061
20130101; C11B 9/0076 20130101; C11D 3/001 20130101; C08K 5/0008
20130101; D06B 1/02 20130101; A61K 8/33 20130101; A61K 8/34
20130101; A61K 8/361 20130101; A61K 2800/56 20130101; C11D 3/2072
20130101; G06F 17/10 20130101; A61L 9/127 20130101; A61Q 19/00
20130101 |
International
Class: |
C11D 3/00 20060101
C11D003/00; C11B 9/00 20060101 C11B009/00; C11D 11/00 20060101
C11D011/00; C11D 3/50 20060101 C11D003/50; A61Q 5/02 20060101
A61Q005/02; A61Q 13/00 20060101 A61Q013/00; A61K 8/73 20060101
A61K008/73; A61K 8/49 20060101 A61K008/49; A61K 8/11 20060101
A61K008/11; A61K 8/81 20060101 A61K008/81; A61K 8/34 20060101
A61K008/34; A61K 8/31 20060101 A61K008/31; A61K 8/37 20060101
A61K008/37; A61K 8/33 20060101 A61K008/33; A61K 8/35 20060101
A61K008/35 |
Claims
1. A delivery system comprising, based on total delivery system
weight, a sum total of from about 0.00025% to about 30% of a
benefit agent that comprises one or more malodor reduction
materials, each of said malodor reduction materials having a MORV
of at least 0.5, said sum total of malodor reduction materials
having a Blocker Index of less than 3 and/or a Blocker Index
average of 3 to about 0.001; and optionally an additional benefit
agent.
2. A delivery system according to claim 1, wherein said malodor
reduction materials have a Fragrance Fidelity Index of less than
3.
3. A delivery system according to claim 2 comprising from about
0.01% to about 80% of said malodor reduction materials.
4. A delivery system according to claim 3 selected from the group
consisting of: a) a Polymer Assisted Delivery (PAD) system
comprising, based on total benefit agent weight, from about 0.1% to
about 50% Malodor reducing composition b) a Molecule-Assisted
Delivery (MAD) system, comprising, based on total benefit agent
weight, from about 0.1% to about 75% Malodor reducing composition.
c) a Cyclodextrin (CD) system comprising, based on total benefit
agent weight, from about 0.1% to about 20% Malodor reducing
composition. d) a Starch Encapsulated Accord (SEA) system
comprising, based on total benefit agent weight, from about 0.1% to
about 80% Malodor reducing composition. e) a Zeolite &
Inorganic Carrier (ZIC) system comprising, based on total benefit
agent weight, from about 0.1% to about 30% Malodor reducing
composition.
5. A Polymer Assisted Delivery (PAD) system according to claim 4,
wherein said Polymer Assisted Delivery (PAD) system comprises a
Polymer Assisted Delivery (PAD) Reservoir system.
6. The Polymer Assisted Delivery (PAD) Reservoir system according
to claim 5, said Polymer Assisted Delivery (PAD) Reservoir system
being a perfume delivery particle that comprises a shell material
and a core material, said shell material encapsulating said core
material, said core material comprising said malodor reduction
materials and said shell comprising a material selected from the
group consisting of polyethylenes; polyamides; polystyrenes;
polyisoprenes; polycarbonates; polyesters; polyacrylates;
aminoplasts; polyvinylamine, polyvinyl formamide, polyolefins,
polyvinyl alcohol, polysaccharides, gelatin; shellac, epoxy resins,
vinyl polymers, water insoluble inorganics, silicone and mixtures
thereof.
7. The Polymer Assisted Delivery (PAD) Reservoir system of claim 6
wherein said shell comprises melamine formaldehyde and/or cross
linked melamine formaldehyde.
8. The Polymer Assisted Delivery (PAD) Reservoir system of claim 6
wherein said shell is coated by a water-soluble cationic polymer
selected from the group that consists of polysaccharides,
cationically modified starch and cationically modified guar,
polysiloxanes, dimethyldiallylammonium polyhalogenides, copolymers
of dimethyldiallylammonium polychloride and vinyl pyrrolidone,
acrylamides, imidazoles, imidazolinium halogenides and imidazolium
halogenides and polyvinyl amine and its copolymers with N-vinyl
formamide.
9. The Polymer Assisted Delivery (PAD) Reservoir system of claim 8
wherein: said coating that coats said shell, comprises a cationic
polymer and an anionic polymer.
10. The Polymer Assisted Delivery (PAD) Reservoir system of claim 9
wherein said cationic polymer comprises hydroxyl ethyl cellulose;
and said anionic polymer comprises carboxyl methyl cellulose.
11. A delivery system according to claim 6, wherein said core
comprises a malodor reduction material selected from the group
consisting of (E)-3,7-dimethylocta-2,6-dien-1-yl palmitate;
1-((2-(tert-butyl)cyclohexyl)oxy)butan-2-ol;
2-(8-isopropyl-6-methylbicyclo[2.2.2]oct-5-en-2-yl)-1,3-dioxolane;
2,2,6,6,7,8,8-heptamethyldecahydro-2H-indeno[4,5-b]furan;
2,3-dihydro-1,1-1H-dimethyl-indene-ar-propanal;
(R,Z)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)pent-1-en-3-one;
3-(6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-2,2-dimethylpropanal;
(Z)-cyclooct-4-en-1-yl methyl carbonate; ethyl dodecanoate;
(Z)-3,7-dimethylocta-1,3,6-triene;
(E)-3,7-dimethylocta-1,3,6-triene;
3a-isopropyl-2,6-dimethyloctahydrobenzofuran; 1,3,4,6,7,8
alpha-hexahydro-1,1,5,5-tetramethyl-2H-2,4
alpha-methanophthalen-8(5H)-one;
3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoind3en-1-yl propanoate;
(E)-cyclohexadec-5-en-1-one;
(1-methyl-2-((1,2,2-trimethylbicyclo[3.1.0]hexan-3-yl)methyl)cyclopropyl)-
methanol; (E)-oxacyclohexadec-13-en-2-one; (E)-dec-4-enal;
(E)-1,1-dimethoxy-3,7-dimethylocta-2,6-diene;
1,1,2,3,3-pentamethyl-1,2,3,5,6,7-hexahydro-4H-inden-4-one;
oxydibenzene; 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl
acetate; 3-methyl-5-phenylpentan-1-ol;
3-(3,3-dimethyl-2,3-dihydro-1H-inden-5-yl)propanal;
3,4,4a,5,6,7,8,8a-octahydrochromen-2-one; 7-methyloctyl acetate;
3,5,5-trimethyl hexyl acetate;
4,5-epoxy-4,11,11-trimethyl-8-methylenebicyclo(7.2.0)undecane;
8,8-dimethyl-3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl
propionate; 1-(5,5-dimethylcyclohex-1-en-1-yl)pent-4-en-1-one;
cis-6-nonen-1-ol; Dodecanenitrile; 2-isopropyl-5-methylphenol;
2,6-di-tert-butyl-4-methylphenol and mixtures thereof.
12. A delivery system according to any of claim 9, wherein said
core material comprises said one or more malodor reduction
materials and said one or more malodor reduction materials having a
vapor pressure of greater than 0.01 torr.
13. A consumer product comprising delivery system according to
claim 1 and a consumer product ingredient.
14. A method of treating and/or cleaning a situs, said method
comprising a) optionally washing, rinsing and/or drying said situs;
b) contacting said situs with a consumer product according to claim
13; and c) optionally washing, rinsing and/or drying said
situs.
15. A situs treated with a consumer product according to claim
13.
16. A process of making a perfume microcapsule comprising: a)
preparing a first solution comprising, based on total solution
weight, from about 20% to about 90%, of a first emulsifier and a
first resin, the ratio of said first emulsifier and said first
resin being from about 0.1:1 to about 10:1; b) preparing a second
solution comprising based on total solution weight from about 20%
to about 95% water, of a second emulsifier and a second resin, the
ratio of said second emulsifier and said second resin being from
about 0:1 to about 3:1; c) combining a core material comprising a
perfume according to claim 1 and said first solution to form a
first composition; d) emulsifying said first composition; e)
combining said first composition and said second solution to form a
second composition and optionally combining any processing aids and
said second composition; f) mixing said second composition for at
least 15 minutes at a temperature of from about 25.degree. C. to
about 100.degree. C. and optionally combining any processing aids
to said second composition; g) optionally combining any scavenger
material, structurant, and/or anti-agglomeration agent with said
second composition during step f) or thereafter h) Optionally spray
drying said second composition.
Description
FIELD OF THE INVENTION
[0001] The present invention relates to delivery systems comprising
malodor reduction compositions, methods of making such delivery
systems and consumer products made with such delivery systems.
BACKGROUND OF THE INVENTION
[0002] Unscented or scented products are desired by consumers as
they may be considered more natural and discreet than scented
products. Manufacturers of unscented or scented products for
controlling malodors rely on malodor reduction ingredients or other
technologies (e.g. filters) to reduce malodors. However,
effectively controlling malodors, for example, amine-based malodors
(e.g. fish and urine), thiol and sulfide-based malodors (e.g.
garlic and onion), C.sub.2-C.sub.12 carboxylic acid based malodors
(e.g. body and pet odor), indole based malodors (e.g. fecal and bad
breath), short chain fatty aldehyde based malodors (e.g. grease)
and geosmin based malodors (e.g. mold/mildew) may be difficult, and
the time required for a product to noticeably reduce malodors may
create consumer doubt as to the product's efficacy on malodors.
Often times, manufacturers incorporate scented perfumes to help
mask these difficult malodors.
[0003] Unfortunately, malodor control technologies typically cover
up the malodor with a stronger scent and thus interfere with the
scent of the perfumed or unperfumed situs that is treated with the
malodor control technology. Thus, limited nature of the current
malodor control technologies is extremely constraining. Thus what
is needed is a broader palette of malodor control technologies so
the perfume community can deliver the desired level of character in
a greater number of situations/applications. Surprisingly,
Applicants recognized that in addition to blocking a malodor's
access to a sensory cell, in order to achieve the desired goal, a
malodor control technology must leave such sensor cell open to
other molecules, for example scent molecules. As a result of such
recognition, Applicants developed delivery systems comprising
malodor reduction compositions that do not unduely interfere with
the scent of the perfumed or unperfumed delivery system, perfumed
or unperfumed products comprising such delivery systems and any
perfumed or unperfumed situs that is treated with such products.
Such delivery systems are disclosed herein.
SUMMARY OF THE INVENTION
[0004] The present invention relates to delivery systems comprising
malodor reduction compositions, methods of making such delivery
systems and consumer products made with such delivery systems. Such
delivery systems do not unduely interfere with the scent of the
perfumed or unperfumed delivery system, perfumed or unperfumed
products comprising such delivery systems and any perfumed or
unperfumed situs that is treated with such products.
DETAILED DESCRIPTION OF THE INVENTION
[0005] As used herein "MORV" is the calculated malodor reduction
value for a subject material. A material's MORV indicates such
material's ability to decrease or even eliminate the perception of
one or more malodors. For purposes of the present application, a
material's MORV is calculated in accordance with method found in
the test methods section of the present application.
[0006] As used herein, the term "perfume" does not include malodor
reduction materials. Thus, the perfume portion of a composition
does not include, when determining the perfume's composition, any
malodor reduction materials found in the composition as such
malodor reduction materials are described herein. In short, if a
material has a malodor reduction value "MORV" that is within the
range of the MORV recited in the subject claim, such material is a
malodor reduction material for purposes of such claim.
[0007] As used herein "cleaning and/or treatment products" means
products comprising fluid laundry detergents, fabric enhancers,
laundry and/or rinse additives, fluid dishwashing detergents, fluid
hard surface cleaning and/or treatment compositions, fluid toilet
bowl cleaners that may or may not be contained in a unit dose
delivery product all for consumer, agricultural, industrial or
institutional use.
[0008] As used herein, "malodor" refers to compounds generally
offensive or unpleasant to most people, such as the complex odors
associated with bowel movements.
[0009] As used herein, "odor blocking" refers to the ability of a
compound to dull the human sense of smell.
[0010] As used herein, the terms "a" and "an" mean "at least
one".
[0011] As used herein, the terms "include", "includes" and
"including" are meant to be non-limiting.
[0012] Unless otherwise noted, all component or composition levels
are in reference to the active portion of that component or
composition, and are exclusive of impurities, for example, residual
solvents or by-products, which may be present in commercially
available sources of such components or compositions.
[0013] All percentages and ratios are calculated by weight unless
otherwise indicated. All percentages and ratios are calculated
based on the total composition unless otherwise indicated.
[0014] It should be understood that every maximum numerical
limitation given throughout this specification includes every lower
numerical limitation, as if such lower numerical limitations were
expressly written herein. Every minimum numerical limitation given
throughout this specification will include every higher numerical
limitation, as if such higher numerical limitations were expressly
written herein. Every numerical range given throughout this
specification will include every narrower numerical range that
falls within such broader numerical range, as if such narrower
numerical ranges were all expressly written herein.
Malodor Reduction Materials
[0015] A non-limiting set of suitable malodor reduction materials
are provided in the tables below. For ease of use, each material in
Tables 1-3 is assigned a numerical indentifier which is found in
the column for each table that is designated Number. Table 4 is a
subset of Table 1, Table 5 is a subset of Table 2 and Table 6 is a
subset of Table 3 and there for Tables 4, 5 and 6 each use the same
numerical identifier as found, respectively, in Tables 1-3.
TABLE-US-00001 Codes A = Vapor Pressure >0.1 torr B = Vapor
Pressure is between 0.01 torr and 0.1 torr C = Calculated logP
<3 D = Calculated logP >3 E = Probability of Ingredient Color
Instability = 0% F = Probability of Ingredient Color Instability
<71% G = Odor Detection Threshold less than p.ol = 8 H = Odor
Detection Threshold greater than p.ol = 8 I = Melamine formaldehyde
PMC Headspace Response Ratio greater than or equal to 10 J =
Melamine formaldehyde PMC leakage less than or equal to 5% K = Log
of liquid dish neat product liquid-air partition coefficient
greater than or equal to -7 L = Log of liquid dish neat product
liquid-air partition coefficient greater than or equal to -5
TABLE-US-00002 TABLE 1 List of materials with at least one MORV
from 1 to 5 Number Material Name CAS Number Comment Code 1
2-ethylhexyl (Z)-3-(4- 5466-77-3 DEFHJ methoxyphenyl)acrylate 2
2,4-dimethyl-2-(5,5,8,8-tetramethyl- 131812-67-4 DFHJ
5,6,7,8-tetrahydronaphthalen-2-yl)- 1,3-dioxolane 3
1,1-dimethoxynon-2-yne 13257-44-8 ACEFHJK 4 para-Cymen-8-ol
1197-01-9 BCGIJK 7 3-methoxy-7,7-dimethyl-10- 216970-21-7 BDEFHJK
methylenebicyclo[4.3.1]decane 9 Methoxycyclododecane 2986-54-1
DEFHJK 10 1,1-dimethoxycyclododecane 950-33-4 DEFHJK 11
(Z)-tridec-2-enenitrile 22629-49-8 DEFHJK 13 Oxybenzone 131-57-7
DEFGJ 14 Oxyoctaline formate 65405-72-3 DFHJK 16
4-methyl-1-oxaspiro[5.5]undecan-4- 57094-40-3 CFGIJK ol 17
7-methyl-2H-benzo[b][1,4]dioxepin- 28940-11-6 CGIK 3(4H)-one 18
1,8-dioxacycloheptadecan-9-one 1725-01-5 DGJ 21
4-(tert-pentyl)cyclohexan-1-one 16587-71-6 ADFGIJKL 22 o-Phenyl
anisol 86-26-0 DEFHJK 23 3a,5,6,7,8,8b-hexahydro- 823178-41-2
DEFHJK 2,2,6,6,7,8,8-heptamethyl-4H- indeno(4,5-d)-1,3-dioxole 25
7-isopropyl-8,8-dimethyl-6,10- 62406-73-9 BDEFHIJK
dioxaspiro[4.5]decane 28 Octyl 2-furoate 39251-88-2 DEFHJK 29 Octyl
acetate 112-14-1 BDEFHJKL 30 octanal propylene glycol acetal
74094-61-4 BDEFHJKL 31 Octanal 124-13-0 ACHIKL 32 Octanal dimethyl
acetal 10022-28-3 ACEFGJKL 33 Myrcene 123-35-3 ADEFGIKL 34 Myrcenol
543-39-5 BCEFGIJK 35 Myrcenyl acetate 1118-39-4 ADEFGJK 36
Myristaldehyde 124-25-4 DFHJK 37 Myristicine 607-91-0 CGJK 38
Myristyl nitrile 629-63-0 DEFHJK 39
2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a- 103614-86-4 DEFHIJK
octahydronaphthalen-1-ol 42 Ocimenol 5986-38-9 BCHIJK 43 Ocimenol
28977-58-4 BCHIJK 47 Nopyl acetate 128-51-8 DEFHJK 48 Nootkatone
4674-50-4 DHJK 49 Nonyl alcohol 143-08-8 BDEFGIJKL 50 Nonaldehyde
124-19-6 ADHIKL 52 12-methyl-14-tetradec-9-enolide 223104-61-8
DFHJK 57 N-ethyl-p-menthane-3-carboxamide 39711-79-0 DEFGIJK 61
1-(3-methylbenzofuran-2-yl)ethan-1- 23911-56-0 CEFHIK one 62
2-methoxynaphthalene 93-04-9 BDEFHK 63 Nerolidol 7212-44-4 DEFHJK
64 Nerol 106-25-2 BCHIK 65 1-ethyl-3- 31996-78-8 ACEFHIJKL
methoxytricyclo[2.2.1.02,6]heptane 67 Methyl (E)-non-2-enoate
111-79-5 ADEFHJKL 68 10-isopropyl-2,7-dimethyl-1- 89079-92-5
BDEFHIJK oxaspiro[4.5]deca-3,6-diene 69
2-(2-(4-methylcyclohex-3-en-1- 95962-14-4 DHJK
yl)propyl)cyclopentan-1-one 70 Myrtenal 564-94-3 ACFHIJKL 71
(E)-4-(2,2,3,6- 54992-90-4 BDEFHIJK
tetramethylcyclohexyl)but-3-en-2- one 74 Myraldyl acetate
53889-39-7 DHJK 75 Musk tibetine 145-39-1 DHIJ 76
1,7-dioxacycloheptadecan-8-one 3391-83-1 DGJ 77 Musk ketone 81-14-1
DHJ 78 Musk ambrette 83-66-9 DHIJ 79 3-methylcyclopentadecan-1-one
541-91-3 DEFHJK 80 (E)-3-methylcyclopentadec-4-en-1- 82356-51-2
DHJK one 82 3-methyl-4-phenylbutan-2-ol 56836-93-2 BCEFHIK 83
1-(4-isopropylcyclohexyl)ethan-1-ol 63767-86-2 BDEFHIJK 85 Milk
Lactone 72881-27-7 DEFHJK 91 Methyl octine carbonate 111-80-8
BDEFHKL 92 Methyl octyl acetaldehyde 19009-56-4 ADFHJKL 93
6,6-dimethoxy-2,5,5-trimethylhex-2- 67674-46-8 ACHIJKL ene 98
Methyl phenylethyl carbinol 2344-70-9 BCEFHIK 100 Methyl stearate
112-61-8 DEFHJ 101 Methyl nonyl acetaldehyde dimethyl 68141-17-3
BDEFHJK acetal 102 Methyl nonyl ketone 112-12-9 BDFHJKL 103 Methyl
nonyl acetaldehyde 110-41-8 BDFHJK 104 Methyl myristate 124-10-7
DEFHJK 105 Methyl linoleate 112-63-0 DEFHJ 106 Methyl lavender
ketone 67633-95-8 CFHJK 108 Methyl isoeugenol 93-16-3 ACEFHK 109
Methyl hexadecanoate 112-39-0 DEFHJK 110 Methyl eugenol 93-15-2
ACEFHK 112 Methyl epijasmonate 1211-29-6 CHJK 113 Methyl
dihydrojasmonate 24851-98-7 DFHJK 114 Methyl diphenyl ether
3586-14-9 DEFHJK 117 Methyl cinnamate 103-26-4 BCEFHK 119 Methyl
chavicol 140-67-0 ADEFHK 120 Methyl beta-naphthyl ketone 93-08-3
CEFHK 122 Methyl 2-octynoate 111-12-6 ACEFHKL 123 Methyl
alpha-cyclogeranate 28043-10-9 ACHIJKL 126 Methoxycitronellal
3613-30-7 ACFGIJK 128 Menthone 1,2-glycerol ketal 67785-70-0 CEFHJ
(racemic) 130 Octahydro-1H-4,7-methanoindene-1- 30772-79-3 BCFHIJKL
carbaldehyde 134 3-(3-(tert-butyl)phenyl)-2- 62518-65-4 BDHJK
methylpropanal 135 (E)-4-(4,8-dimethylnona-3,7-dien-1- 38462-23-6
DEFHJK yl)pyridine 137 (E)-trideca-3,12-dienenitrile 134769-33-8
DEFHJK 140 2,2-dimethyl-3-(m-tolyl)propan-1-ol 103694-68-4 CEFHIJK
141 2,4-dimethyl-4,4a,5,9b- 27606-09-3 CEFHJK
tetrahydroindeno[1,2-d][1,3]dioxine 142 Maceal 67845-30-1 BDFHJK
143 4-(4-hydroxy-4- 31906-04-4 CHJ methylpentyl)cyclohex-3-ene-1-
carbaldehyde 145 1-Limonene 5989-54-8 ADEFGIJKL 146
(Z)-3-hexen-1-yl-2-cyclopenten-1- 53253-09-1 BDHK one 148 Linalyl
octanoate 10024-64-3 DEFHJ 149 Linalyl isobutyrate 78-35-3 BDHJK
152 Linalyl benzoate 126-64-7 DFHJ 153 Linalyl anthranilate
7149-26-0 DFHJ 155 Linalool oxide (furanoid) 60047-17-8 BCHIJK 156
linalool oxide 1365-19-1 CGIJK 158 (2Z,6E)-3,7-dimethylnona-2,6-
61792-11-8 BDEFHJK dienenitrile 159 3-(4-methylcyclohex-3-en-1-
6784-13-0 ACFHIJK yl)butanal 161 (2,5-dimethyl-1,3-dihydroinden-2-
285977-85-7 CEFHJK yl)methanol 162 3-(4-(tert-butyl)phenyl)-2-
80-54-6 BDHJK methylpropanal 167 (E)-1-(1-methoxypropoxy)hex-3-ene
97358-54-8 ACEFGJKL 168 Leaf acetal 88683-94-7 ACEFGJKL 170
1-Carveol 2102-58-1 BCHIJK 174 Lauryl alcohol 112-53-8 DEFGJK 175
Lauryl acetate 112-66-3 DEFHJK 176 Lauric acid 143-07-7 DEFHJ 177
Lactojasmone 7011-83-8 BDEFHIJKL 178 Lauraldehyde 112-54-9 BDFHJK
179 3,6-dimethylhexahydrobenzofuran- 92015-65-1 BCEFHIJKL 2(3H)-one
182 4-(1-ethoxyvinyl)-3,3,5,5- 36306-87-3 BDFHIJK
tetramethylcyclohexan-1-one 183 Khusimol 16223-63-5 CEFHJK 184
5-(sec-butyl)-2-(2,4- 117933-89-8 DEFHJ
dimethylcyclohex-3-en-1-yl)-5- methyl-1,3-dioxane 185
(1-methyl-2-((1,2,2- 198404-98-7 DEFHJK
trimethylbicyclo[3.1.0]hexan-3- yl)methyl)cyclopropyl)methanol 186
2-propylheptanenitrile 208041-98-9 ADEFHIJKL 187
(E)-6-(pent-3-en-1-yl)tetrahydro-2H- 32764-98-0 BCFHIKL pyran-2-one
189 2-hexylcyclopentan-1-one 13074-65-2 BDFHJKL 190
2-methyl-4-phenyl-1,3-dioxolane 33941-99-0 BCEFGIK 192
2,6,9,10-tetramethyl-1- 71078-31-4 BDEFHIJK
oxaspiro(4.5)deca-3,6-diene 193 Isopulegol 89-79-2 BCEFHIJKL 195
Isopropyl palmitate 142-91-6 DEFHJ 196 Isopropyl myristate 110-27-0
DEFHJK 197 Isopropyl dodecanoate 10233-13-3 DEFHJK 199
Isopimpinellin 482-27-9 CFGJ 206 Iso3-methylcyclopentadecan-1-one
3100-36-5 DEFGJK 208 Isomenthone 491-07-6 ADEFGIJKL 209 Isojasmone
95-41-0 BDFHJKL 210 Isomenthone 36977-92-1 ADEFGIJKL 211 Isohexenyl
cyclohexenyl 37677-14-8 DFHJK carboxaldehyde 212 Isoeugenyl benzyl
ether 120-11-6 DFHJ 215 1-((2S,3S)-2,3,8,8-tetramethyl- 54464-57-2
DHJK 1,2,3,4,5,6,7,8-octahydronaphthalen- 2-yl)ethan-1-one 218
Isocyclocitral 1335-66-6 ACFHIJKL 221 Isobutyl quinoline 65442-31-1
DEFHJK 227 Isobornylcyclohexanol 68877-29-2 DEFHJK 228 Isobornyl
propionate 2756-56-1 BDEFHIJK 229 Isobornyl isobutyrate 85586-67-0
BDEFHIJK 230 Isobornyl cyclohexanol 66072-32-0 DEFHJK 231 Isobornyl
acetate 125-12-2 ADEFHIJKL 233 Isobergamate 68683-20-5 DEFHJK 234
Isoamyl undecylenate 12262-03-2 DEFHJK 238 Isoamyl laurate
6309-51-9 DEFHJK 242 Isoambrettolide 28645-51-4 DGJ 243 Irisnitrile
29127-83-1 ADEFHKL 244 Indolene 68527-79-7 DEFHJ 246
Indol/Hydroxycitronellal Schiff base 67801-36-9 DEFHJ 247
4,4a,5,9b-tetrahydroindeno[1,2- 18096-62-3 BCEFGJK d][1,3]dioxine
249 Hydroxy-citronellol 107-74-4 CEFGIJK 252
2-cyclododecylpropan-1-ol 118562-73-5 DEFHJK 253 Hydrocitronitrile
54089-83-7 CEFHJK 254 Hydrocinnamyl alcohol 122-97-4 BCEFHIK 256
Hydratropaldehyde dimethyl acetal 90-87-9 ACEFHJK 259
5-ethyl-4-hydroxy-2-methylfuran- 27538-09-6 CFGIK 3(2H)-one 260
2,3-dihydro-3,3-dimethyl-1H-indene- 173445-44-8 DHJK 5-propanal 261
3-(3,3-dimethyl-2,3-dihydro-1H- 173445-65-3 DHJK
inden-5-yl)propanal 263 Hexyl octanoate 1117-55-1 DEFHJK 267 Hexyl
hexanoate 6378-65-0 DEFHJKL 269 Hexyl cinnamic aldehyde 101-86-0
DHJ 271 Hexyl benzoate 6789-88-4 DEFHJK 274 Hexenyl tiglate
84060-80-0 BDEFHJK 276 (E)-3,7-dimethylocta-2,6-dien-1-yl 3681-73-0
DEFHJ palmitate 277 Hexadecanolide 109-29-5 DEFGJK 278
2-butyl-4,4,6-trimethyl-1,3-dioxane 54546-26-8 ADEFHIJKL 280 Ethyl
(1R,2R,3R,4R)-3- 116126-82-0 BDEFHIJK
isopropylbicyclo[2.2.1]hept-5-ene-2- carboxylate 281
3a,4,5,6,7,7a-hexahydro-1H-4,7- 5413-60-5 CEFGJK methanoinden-6-yl
acetate 285 2-(1-(3,3- 141773-73-1 DEFHJ
dimethylcyclohexyl)ethoxy)-2- methylpropyl propionate 286
Heliotropine diethyl acetal 40527-42-2 CEFGJ 288 Helional 1205-17-0
CHJK 289 (E)-oxacyclohexadec-13-en-2-one 111879-80-2 DGJK 290
Gyrane 24237-00-1 ADEFHIJKL 292 Guaiol 489-86-1 DEFHJK 293
1-(2,6,6-trimethylcyclohex-2-en-1- 68611-23-4 DHJK yl)pentan-3-one
294 Ethyl 2-ethyl-6,6-dimethylcyclohex- 57934-97-1 BDEFHIJK
2-ene-1-carboxylate 295 Germacrene B 15423-57-1 DEFHJK 296
Germacrene D 23986-74-5 DEFHJK 300 Geranyl phenylacetate 102-22-7
DFHJ 301 Geranyl phenyl acetate 71648-43-6 DFHJ 303 Geranyl
linalool 1113-21-9 DFHJ 307 Geranyl cyclopentanone 68133-79-9 DHJK
316 gamma-Undecalactone (racemic) 104-67-6 DEFHJKL 317
gamma-Terpinyl acetate 10235-63-9 BDHJK 318 gamma-Terpineol
586-81-2 BCGIJK 321 gamma-Nonalactone 104-61-0 BCEFHIKL 322
gamma-Muurolene 30021-74-0 DEFHJKL 323 gamma-(E)-6-(pent-3-en-1-
63095-33-0 BCEFHKL yl)tetrahydro-2H-pyran-2-one 324 gamma-Ionone
79-76-5 BDEFHIJK 325 gamma-Himachalene 53111-25-4 BDEFHJKL 328
gamma-Gurjunene 22567-17-5 DEFHJKL 329 gamma-Eudesmol 1209-71-8
DFHJK 330 gamma-Dodecalactone 2305-05-7 DEFHJK 331 gamma-Damascone
35087-49-1 BDEFHIJK
332 gamma-Decalactone 706-14-9 BDEFHIJKL 333 gamma-Cadinene
39029-41-9 DEFHJKL 334 1-(3,3-dimethylcyclohexyl)pent-4- 56973-87-6
BDEFHJK en-1-one 335 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8- 1222-05-5
DEFHJK hexahydrocyclopenta[g]isochromene 336 Furfuryl octanoate
39252-03-4 DEFHJK 338 Furfuryl hexanoate 39252-02-3 CEFHJK 339
Furfuryl heptanoate 39481-28-2 CEFHJK 342 2-methyldecanenitrile
69300-15-8 BDEFHJKL 343 8,8-dimethyl-3a,4,5,6,7,7a- 76842-49-4
DEFHJK hexahydro-1H-4,7-methanoinden-6- yl propionate 344 Ethyl
(3aR,4S,7R,7aR)-octahydro- 80657-64-3 DEFHIJK
3aH-4,7-methanoindene-3a- carboxylate 347 Diethyl cyclohexane-1,4-
72903-27-6 CEFHJK dicarboxylate 349 (6-isopropyl-9-methyl-1,4-
63187-91-7 CEFHJ dioxaspiro[4.5]decan-2-yl)methanol 350
2-isobutyl-4-methyltetrahydro-2H- 63500-71-0 BCEFHIJK pyran-4-ol
352 Undec-10-enenitrile 53179-04-7 BDEFHJK 353
(Z)-6-ethylideneoctahydro-2H-5,8- 69486-14-2 CEFGJK
methanochromen-2-one 356 3-(2-ethylphenyl)-2,2- 67634-15-5 BDHJK
dimethylpropanal 358 (E)-4,8-dimethyldeca-4,9-dienal 71077-31-1
BDFHJK 359 (E)-4-((3aR,4R,7R,7aR)- 501929-47-1 DEFHJK
1,3a,4,6,7,7a-hexahydro-5H-4,7- methanoinden-5-ylidene)-3-
methylbutan-2-ol 360 8,8-dimethyl-3a,4,5,6,7,7a- 171102-41-3 DEFHJK
hexahydro-1H-4,7-methanoinden-6- yl acetate 361
3-(4-ethylphenyl)-2,2- 134123-93-6 DEFHJK dimethylpropanenitrile
362 2-heptylcyclopentan-1-one 137-03-1 DFHJKL 363 1-ethoxyethoxy
Cyclododecane 389083-83-4 DEFHJK 364 3-cyclohexene-1-carboxylic
acid, 815580-59-7 ACHIJKL 2,6,6-trimethyl-, methyl ester 368
Farnesyl acetate 29548-30-9 DEFHJK 369 Farnesol 4602-84-0 DEFHJK
370 Oxacyclohexadecan-2-one 106-02-5 DEFGJK 371
1-cyclopentadec-4-en-1-one 14595-54-1 DEFGJK 372
1-cyclopentadec-4-en-1-one 35720-57-1 DEFGJK 373 2-methoxy-4-(4-
128489-04-3 CGJ methylenetetrahydro-2H-pyran-2- yl)phenol 374
Eugenyl acetate 93-28-7 CFHJK 375 Eugenol 97-53-0 CHIK 377
Ethylmethylphenylglycidate 77-83-8 CFHJK 378 Ethylene brassylate
105-95-3 DFGJ 381 Ethyl undecylenate 692-86-4 DEFHJK 385 Ethyl
palmitate 628-97-7 DEFHJ 386 Ethyl nonanoate 123-29-5 BDEFHJKL 388
Ethyl myristate 124-06-1 DEFHJK 390 Ethyl linalool 10339-55-6
BCEFHJK 391 Ethyl laurate 106-33-2 DEFHJK 394 Ethyl hexyl ketone
925-78-0 ADFHIKL 397 Ethyl decanoate 110-38-3 BDEFHJK 398 Ethyl
gamma-Safranate 35044-57-6 ADHIJK 407 Ethyl 3-phenylglycidate
121-39-1 CGJK 413 6-ethyl-2,10,10-trimethyl-1- 79893-63-3 BDEFHIJK
oxaspiro[4.5]deca-3,6-diene 414 Elemol 639-99-6 DEFHJK 415
(2-(1-ethoxyethoxy)ethyl)benzene 2556-10-7 BCEFHJK 416
(E)-3-methyl-5-(2,2,3- 67801-20-1 DHJK
trimethylcyclopent-3-en-1-yl)pent-4- en-2-ol 417 d-xylose 58-86-6
CGIJ 418 (E)-4-((3aS,7aS)-octahydro-5H-4,7- 30168-23-1 DFHJK
methanoinden-5-ylidene)butanal 421 Dodecanal dimethyl acetal
14620-52-1 DEFHJK 424 d-Limonene 5989-27-5 ADEFGIJKL 425
Dipropylene Glycol 25265-71-8 CEFGIK 426 Dispirone 83863-64-3
BDEFHJK 428 Diphenyloxide 101-84-8 BDEFHK 429 Diphenylmethane
101-81-5 DEFGK 432 Dimethyl benzyl carbinyl butyrate 10094-34-5
DEFHJK 436 2,6-dimethyloct-7-en-4-one 1879-00-1 ADEFHIJKL 441
Octahydro-1H-4,7-methanoinden-5- 64001-15-6 DEFHJKL yl acetate 444
Dihydrocarveol acetate 20777-49-5 BDEFHIJK 445 Dihydrocarveol
619-01-2 BCEFHIJKL 449 Dihydro Linalool 18479-51-1 BCEFGIJKL 450
Dihydro Isojasmonate 37172-53-5 DHJK 453 Dibutyl sulfide 544-40-1
ADEFHIKL 457 Dibenzyl 103-29-7 DEFGJK 459 delta-Undecalactone
710-04-3 DEFHJKL 461 delta-Elemene 20307-84-0 BDEFHJK 462
delta-Guaiene 3691-11-0 DEFHJKL 463 delta-Dodecalactone 713-95-1
DEFHJK 464 delta-Decalactone 705-86-2 BDEFHIJKL 465 delta-Cadinene
483-76-1 DEFHJKL 466 delta-damascone 57378-68-4 ADHIJK 467
delta-Amorphene 189165-79-5 DEFHJKL 468 delta-3-Carene 13466-78-9
ADEFGIJKL 470 Decylenic alcohol 13019-22-2 BDEFHJK 471 Decyl
propionate 5454-19-3 DEFHJK 473 Decanal diethyl acetal 34764-02-8
DEFHJK 474 Decahydro-beta-naphthol 825-51-4 BCEFGIK 475
1-cyclohexylethyl (E)-but-2-enoate 68039-69-0 BDFHJK 478
3-(4-isopropylphenyl)-2- 103-95-7 BDFHJK methylpropanal 479
Cyclotetradecane 295-17-0 DEFGJKL 480 Cyclopentadecanone 502-72-7
DEFGJK 482 Cyclohexyl salicylate 25485-88-5 DFGJ 484
3a,4,5,6,7,7a-hexahydro-1H-4,7- 113889-23-9 DEFHJK
methanoinden-6-yl butyrate 485 Cyclic ethylene dodecanedioate
54982-83-1 DFGJ 486 8,8-dimethyl-1,2,3,4,5,6,7,8- 68991-97-9 DHJK
octahydronaphthalene-2- carbaldehyde 487
3a,4,5,6,7,7a-hexahydro-1H-4,7- 67634-20-2 DEFHJK methanoinden-5-yl
isobutyrate 488 Curzerene 17910-09-7 DHJK 491 Cumic alcohol
536-60-7 CHIJK 493 Coumarone 1646-26-0 BCEFHIK 497
2-(3-phenylpropyl)pyridine 2110-18-1 CEFHJK 498 Dodecanenitrile
2437-25-4 DEFHJK 501 (E)-cycloheptadec-9-en-1-one 542-46-1 DEFGJ
502 Citryl acetate 6819-19-8 DFHJK 503 Citrus Propanol 15760-18-6
CEFHIJK 505 Citronitrile 93893-89-1 CEFHJK 519 Citral propylene
glycol acetal 10444-50-5 CEFHJK 520 Citral dimethyl acetal
7549-37-3 BCEFHJK 521 Citral diethyl acetal 7492-66-2 BDEFHJK 524
cis-Ocimene 3338-55-4 ADGIKL 527 cis-Limonene oxide 13837-75-7
ADEFGIJKL 529 Cis-iso-ambrettolide 36508-31-3 DGJ 530 cis-6-nonenol
35854-86-5 BCEFHIKL 531 cis-carveol 1197-06-4 BCHIJK 532
cis-4-Decen-1-al 21662-09-9 ADHKL 534 cis-3-hexenyl-cis-3-hexenoate
61444-38-0 BDEFHJK 537 cis-3-Hexenyl salicylate 65405-77-8 DEFGJ
541 Cis-3-hexenyl Benzoate 25152-85-6 DEFHJK 544 cis-3-Hexenyl
2-methylbutyrate 53398-85-9 ADEFHJKL 546 cis-3, cis-6-nonadienol
53046-97-2 ACEFHK 548 Cinnamyl propionate 103-56-0 DEFHJK 550
Cinnamyl isobutyrate 103-59-3 DEFHJK 551 Cinnamyl formate 104-65-4
BCEFHK 552 Cinnamyl cinnamate 122-69-0 DHJ 553 Cinnamyl acetate
103-54-8 BCEFHK 555 Cinnamic alcohol 104-54-1 BCEFHIK 558 Cetyl
alcohol 36653-82-4 DEFHJ 559 (E)-1-(2,6,6-trimethylcyclohex-2-en-
79-78-7 DHJK 1-yl)hepta-1,6-dien-3-one 560
2-methyl-4-(2,6,6-trimethylcyclohex- 65405-84-7 DFHJK
1-en-1-yl)butanal 561 (3aR,5aR,9aR,9bR)-3a,6,6,9a- 3738-00-9 DEFHJK
tetramethyldodecahydronaphtho[2,1- b]furan 562
1,6-dioxacycloheptadecan-7-one 6707-60-4 DGJ 563
1-(6-(tert-butyl)-1,1-dimethyl-2,3- 13171-00-1 DEFHJK
dihydro-1H-inden-4-yl)ethan-1-one 565 Cedryl methyl ether
19870-74-7 ADEFHJK 566 Cedryl formate 39900-38-4 BDEFHJK 567 Cedryl
acetate 77-54-3 DEFHJK 568 (4Z,8Z)-1,5,9-trimethyl-13- 71735-79-0
DFHJK oxabicyclo[10.1.0]trideca-4,8-diene 569 Cedrol 77-53-2 DEFHJK
570 5-methyl-1-(2,2,3- 139539-66-5 DEFHJK
trimethylcyclopent-3-en-1-yl)-6- oxabicyclo[3.2.1]octane 571
5-methyl-1-(2,2,3- 426218-78-2 DFHJ
trimethylcyclopent-3-en-1-yl)-6- oxabicyclo[3.2.1]octane 572
1,1,2,3,3-pentamethyl-1,2,3,5,6,7- 33704-61-9 BDEFHIJK
hexahydro-4H-inden-4-one 573 Caryophyllene alcohol acetate
32214-91-8 DEFHJK 574 Caryolan-1-ol 472-97-9 DEFHJK 577 Carvyl
acetate 97-42-7 BDHIJK 578 Caprylnitrile 124-12-9 ACEFGIKL 580
Caprylic alcohol 111-87-5 ACEFGIKL 581 Caprylic acid 124-07-2
BCEFHIK 582 Capric acid 334-48-5 DEFHJK 584 Capraldehyde 112-31-2
ADHKL 586 3-(4-methoxyphenyl)-2- 5462-06-6 BCHJK methylpropanal 587
Camphorquinone 10373-78-1 ACEFGIJK 589 Camphene 79-92-5 ADEFGIJKL
591 Ethyl 2-methyl-4-oxo-6- 59151-19-8 DHJ
pentylcyclohex-2-ene-1-carboxylate 592 Butylated hydroxytoluene
128-37-0 DEFGIJK 594 Butyl stearate 123-95-5 DEFHJ 595 Butyl
butyryl lactate 7492-70-8 CEFGJK 599 Butyl 10-undecenoate 109-42-2
DEFHJK 600 2-methyl-4-(2,2,3- 72089-08-8 DEFHJK
trimethylcyclopent-3-en-1-yl)butan- 1-ol 601
3-(4-(tert-butyl)phenyl)propanal 18127-01-0 BDHJK 603 Bornyl
isobutyrate 24717-86-0 BDEFHIJK 604 Bornyl acetate 76-49-3
ADEFHIJKL 606 2-ethoxy-2,6,6-trimethyl-9- 68845-00-1 BDEFHJK
methylenebicyclo[3.3.1]nonane 607 (ethoxymethoxy)cyclododecane
58567-11-6 DEFHJK 608 Bisabolene 495-62-5 DEFHJK 609 Bigarade oxide
72429-08-4 ADEFHJKL 610 beta-Vetivone 18444-79-6 DHJK 611
beta-Terpinyl acetate 10198-23-9 BDHJK 612 beta-Terpineol 138-87-4
BCGIJK 613 beta-Sinensal 60066-88-8 DHJK 614
beta-Sesquiphellandrene 20307-83-9 DEFHJK 615 beta-Selinene
17066-67-0 BDEFGJK 616 beta-Santalol 77-42-9 DEFHJK 618 beta-Pinene
127-91-3 ADEFGIJKL 620 beta-Naphthyl ethyl ether 93-18-5 BDEFHJK
621 beta-Patchoulline 514-51-2 BDEFGJKL 624 beta-Himachalene Oxide
57819-73-5 BDFHJK 625 beta-Himachalene 1461-03-6 DEFHJKL 626
beta-Guaiene 88-84-6 DEFHJKL 627 (2,2-dimethoxyethyl)benzene
101-48-4 DHJK 628 beta-Farnesene 18794-84-8 DEFHJK 631 beta-Copaene
18252-44-3 BDEFHJKL 632 beta-Cedrene 546-28-1 BDEFGJKL 633
beta-Caryophyllene 87-44-5 DEFHJKL 635 beta-Bisabolol 15352-77-9
DFHJK 636 Beta ionone epoxide 23267-57-4 BDEFHIJK 638 Bergaptene
484-20-8 CGJ 639 Benzyl-tert-butanol 103-05-9 CEFGJK 644 Benzyl
laurate 140-25-0 DEFHJ 649 Benzyl dimethyl carbinol 100-86-7
BCEFGIK 650 Benzyl cinnamate 103-41-3 DHJ 653 Benzyl benzoate
120-51-4 DHJ 655 Benzophenone 119-61-9 DEFHK 658 7-isopentyl-2H-
362467-67-2 DHJ benzo[b][1,4]dioxepin-3(4H)-one 659
2'-isopropyl-1,7,7- 188199-50-0 DEFHJK
trimethylspiro[bicyclo[2.2.1]heptane- 2,4'-[1,3]dioxane] 660
4-(4-methylpent-3-en-1-yl)cyclohex- 21690-43-7 DEFHJK
3-ene-1-carbonitrile 661 Aurantiol 89-43-0 DEFHJ 663 Anisyl
phenylacetate 102-17-0 DFHJ 668 Methyl (E)-octa-4,7-dienoate
189440-77-5 ACEFHKL 671 Amyl Cinnamate 3487-99-8 DEFHJK 673
(3aR,5aS,9aS,9bR)-3a,6,6,9a- 6790-58-5 DEFHJK
tetramethyldodecahydronaphtho[2,1- b]furan 674
(4aR,5R,7aS,9R)-2,2,5,8,8,9a- 211299-54-6 DEFHJK
hexamethyloctahydro-4H-4a,9- methanoazuleno[5,6-d][1,3]dioxole 675
2,5,5-trimethyl-1,2,3,4,5,6,7,8- 71832-76-3 DEFHJK
octahydronaphthalen-2-ol 676 2,5,5-trimethyl-1,2,3,4,5,6,7,8-
41199-19-3 DEFHJK octahydronaphthalen-2-ol 677 1-((2-(tert-
139504-68-0 DEFHJK butyl)cyclohexyl)oxy)butan-2-ol 678
(3S,5aR,7aS,11aS,11bR)-3,8,8,11a- 57345-19-4 DEFHJ
tetramethyldodecahydro-5H-3,5a-
epoxynaphtho[2,1-c]oxepine 679 2,2,6,6,7,8,8-heptamethyldecahydro-
476332-65-7 ADEFHJK 2H-indeno[4,5-b]furan 680
2,2,6,6,7,8,8-heptamethyldecahydro- 647828-16-8 ADEFHJK
2H-indeno[4,5-b]furan 681 Amber acetate 37172-02-4 BDEFHJK 682
Alpinofix .RTM. 811436-82-5 DEFHJ 683 alpha-Thujone 546-80-5
ADEFGIJKL 684 alpha-Vetivone 15764-04-2 DHJK 686 alpha-Terpinyl
propionate 80-27-3 BDEFHJK 691 alpha-Sinensal 17909-77-2 DHJK 692
alpha-Selinene 473-13-2 BDEFHJK 693 alpha-Santalene 512-61-8
ADEFHJKL 694 alpha-Santalol 115-71-9 DEFHJK 696 alpha-Patchoulene
560-32-7 ADEFHJKL 697 alpha-neobutenone 56973-85-4 BDHJK 698
alpha-Muurolene 10208-80-7 DEFHJKL 700 alpha-methyl ionone 127-42-4
BDHJK 702 alpha-Limonene 138-86-3 ADEFGIJKL 704 alpha-Irone 79-69-6
BDHJK 706 alpha-Humulene 6753-98-6 DEFHJK 707 alpha-Himachalene
186538-22-7 BDEFHJK 708 alpha-Gurjunene 489-40-7 BDEFHJKL 709
alpha-Guaiene 3691-12-1 DEFHJKL 710 alpha-Farnesene 502-61-4 DEFHJK
711 alpha-Fenchene 471-84-1 ADEFGIJKL 712 alpha-Eudesmol 473-16-5
DEFHJK 713 alpha-Curcumene 4176-17-4 DEFHJK 714 alpha-Cubebene
17699-14-8 ADEFHJKL 715 alpha-Cedrene epoxide 13567-39-0 ADEFHJK
716 alpha-Cadinol 481-34-5 DEFHJK 717 alpha-Cadinene 24406-05-1
DEFHJKL 718 alpha-Bisabolol 515-69-5 DFHJK 719 alpha-bisabolene
17627-44-0 DEFHJK 720 alpha-Bergamotene 17699-05-7 BDEFHJKL 721
alpha-Amylcinnamyl alcohol 101-85-9 DEFHJ 722 alpha-Amylcinnamyl
acetate 7493-78-9 DEFHJ 723 alpha-Amylcinnamaldehyde diethyl
60763-41-9 DEFHJ acetal 724 alpha-Amylcinnamaldehyde 122-40-7 DHJK
725 alpha-Amorphene 23515-88-0 DEFHJKL 726 alpha-Agarofuran
5956-12-7 BDEFHJK 727 1-methyl-4-(4-methyl-3-penten-1- 52475-86-2
DFHJK yl)-3-Cyclohexene-1-carboxaldehyde 730 1-Phenyl-2-pentanol
705-73-7 CEFHK 731 1-Phenyl-3-methyl-3-pentanol 10415-87-9 CEFHJK
733 2,3,4-trimethoxy-benzaldehyde 2103-57-3 BCGI 735
2,4,5-trimethoxy-benzaldehyde 4460-86-0 BCG 736
2,4,6-trimethoxybenzaldehyde 830-79-5 BCGI 738 2,4-Nonadienal
6750-03-4 ACHKL 741 2,6,10-Trimethylundecanal 105-88-4 BDFGJK 742
alpha,4-Dimethyl benzenepropanal 41496-43-9 ACHJK 746 Allyl
cyclohexyl propionate 2705-87-5 BDEFHJK 748 Allyl amyl glycolate
67634-00-8 BCEFGJK 750 Allo-aromadendrene 25246-27-9 BDEFHJKL 752
Aldehyde C-11 143-14-6 ADHJK 754 Methyl (E)-2-(((3,5- 94022-83-0
DEFHJ dimethylcyclohex-3-en-1- yl)methylene)amino)benzoate 757
2,6,10-trimethylundec-9-enal 141-13-9 BDFHJK 758
Acetoxymethyl-isolongifolene 59056-62-1 BDEFHJK (isomers) 763
Acetate C9 143-13-5 BDEFHJKL 764 Acetarolle .RTM. 744266-61-3 DFHJK
766 Acetaldehyde phenylethyl propyl 7493-57-4 CEFHJK acetal 767
Acetaldehyde dipropyl acetal 105-82-8 ACEFGIKL 768 Acetaldehyde
benzyl 2-methoxyethyl 7492-39-9 BCEFHJK acetal 769
(Z)-2-(4-methylbenzylidene)heptanal 84697-09-6 DHJ 770 9-decenal
39770-05-3 ADHKL 771 8-Hexadecenolide 123-69-3 DGJ 772
7-Methoxycoumarin 531-59-9 CHK 774 7-epi-alpha-Selinene 123123-37-5
BDEFHJK 775 7-eip-alpha-Eudesmol 123123-38-6 DEFHJK 776
7-Acetyl-1,1,3,4,4,6- 1506-02-1 DEFHJ hexamethyltetralin 778
6-Isopropylquinoline 135-79-5 CEFHJK 781
6,6-dimethyl-2-norpinene-2- 33885-51-7 BCFHJK propionaldehyde 782
6,10,14-trimethyl-2-Pentadecanone 502-69-2 DEFHJK 786
5-Isopropenyl-2-methyl-2- 13679-86-2 ACGIJKL vinyltetrahydrofuran
788 5-Cyclohexadecenone 37609-25-9 DEFGJK 791 4-Terpinenol 562-74-3
BCHIJK 792 4-Pentenophenone 3240-29-7 BCEFHIK 800 4-Carvomenthenol
28219-82-1 BCHIJK 802 4,5,6,7-Tetrahydro-3,6- 494-90-6 BCEFHIJKL
dimethylbenzofuran 803 4-(p-Methoxyphenyl)-2-butanone 104-20-1
BCEFHJK 804 3-Thujopsanone 25966-79-4 BDEFHJK 805
3-Propylidenephthalide 17369-59-4 CEFHK 806 3-Nonylacrolein
20407-84-5 BDFHJK 807 3-Methyl-5-phenyl-1-pentanal 55066-49-4
BDFHJK 814 3-Hexenyl isovalerate 10032-11-8 ADEFHJKL 821
3,6-Dimethyl-3-octanyl acetate 60763-42-0 ADEFHIJKL 824
3,4,5-trimethoxybenzaldehyde 86-81-7 BCGIK 826 3-(p- 7775-00-0
BDFHJK Isopropylphenyl)propionaldehyde 827 2-Undecenenitrile
22629-48-7 BDEFHJK 828 2-Undecenal 2463-77-6 ADHJK 829
2-trans-6-trans-Nonadienal 17587-33-6 ACHKL 831 2-Phenylethyl
butyrate 103-52-6 DEFHJK 833 2-Phenyl-3-(2-furyl)prop-2-enal
57568-60-2 CHJ 834 2-Phenoxyethanol 122-99-6 BCEFGIK 837
2-Nonen-1-al 2463-53-8 ADHKL 839 2-Nonanol 628-99-9 BDEFGIKL 840
2-Nonanone 821-55-6 ADFHIKL 849 2-Isobutyl quinoline 93-19-6 CEFHJK
850 2-Hexylidene cyclopentanone 17373-89-6 DFHJKL 852 2-Heptyl
tetrahydrofuran 2435-16-7 BDEFHJKL 856 2-Decenal 3913-71-1 ADHKL
864 2,6-Nonadienal 26370-28-5 ACHKL 865 2,6-Nonadien-1-ol 7786-44-9
ACEFHK 866 2,6-dimethyl-octanal 7779-07-9 ADFGIJKL 868 1-Decanol
112-30-1 BDEFGJK 869 1-Hepten-1-ol, 1-acetate 35468-97-4 ACEFHKL
870 10-Undecen-1-ol 112-43-6 DEFHJK 871 10-Undecenal 112-45-8 ADHJK
872 10-epi-gamma-Eudesmol 15051-81-7 DFHJK 873 1,8-Thiocineol
68391-28-6 ADEFHIJKL 876 1,3,5-undecatriene 16356-11-9 ADEFHJKL 877
1,2-Dihydrolinalool 2270-57-7 BCEFGIJKL 878
1,3,3-trimethyl-2-norbornanyl 13851-11-1 ADEFHIJKL acetate 879
1,1,2,3,3-Pentamethylindan 1203-17-4 ADHIJKL 881
(Z)-6,10-dimethylundeca-5,9-dien-2- 3239-37-0 DEFHJK yl acetate 884
(Z)-3-Dodecenal 68141-15-1 BCFHJK 885 (S)-gamma-Undecalactone
74568-05-1 DEFHJKL 886 (R)-gamma-Undecalactone 74568-06-2 DEFHJKL
890 (E)-6,10-dimethylundeca-5,9-dien-2- 3239-35-8 DEFHJK yl acetate
892 (2Z)-3-methyl-5-phenyl-2- 53243-59-7 DEFHJK Pentenenitrile 893
(2S,5S,6S)-2,6,10,10-tetramethyl-1- 65620-50-0 DFHIJK
oxaspiro[4_5]decan-6-ol 894 (2E)-3-methyl-5-phenyl-2- 53243-60-0
CEFHJK pentenenitrile 897 (+)-Dihydrocarveol 22567-21-1 BCEFHIJKL
905 Menthone 89-80-5 ADEFGIJKL 908 (R,E)-2-methyl-4-(2,2,3-
185068-69-3 CHJK trimethylcyclopent-3-en-1-yl)but-2- en-1-ol 912
2-(8-isopropyl-6- 68901-32-6 DEFHJK
methylbicyclo[2.2.2]oct-5-en-2-yl)- 1,3-dioxolane 913 gamma-methyl
ionone 7388-22-9 BDHIJK 914 3-(3-isopropylphenyl)butanal
125109-85-5 BDHJK 916 3-(1-ethoxyethoxy)-3,7- 40910-49-4 BDEFHJK
dimethylocta-1,6-diene 919 3a,4,5,6,7,7a-hexahydro-1H-4,7-
17511-60-3 CEFHJK methanoinden-6-yl propionate 920 Bulnesol
22451-73-6 DEFHJK 922 Benzyl phenylacetate 102-16-9 DHJ 923 Benzoin
119-53-9 CEFHJ 924 (E)-1,2,4-trimethoxy-5-(prop-1-en-1- 2883-98-9
BCFGJK yl)benzene 925 alpha,alpha,6,6-tetramethyl 33885-52-8 BDFHJK
bicyclo[3.1.1]hept-2-ene-propanal 926 7-epi-sesquithujene
159407-35-9 DEFHJKL 927 5-Acetyl-1,1,2,3,3,6- 15323-35-0 DEFHJK
hexamethylindan 928 3-Methylphenethyl alcohol 1875-89-4 BCEFHIK 929
3,6-Nonadien-1-ol 76649-25-7 ACEFHK 930 2-Tridecenal 7774-82-5
BDFHJK 933 Patchouli alcohol 5986-55-0 DEFHIJK 937 p-Cresyl
isobutyrate 103-93-5 BDHJK 939 p-Cresyl n-hexanoate 68141-11-7
DEFHJK 941 5-hexyl-4-methyldihydrofuran- 67663-01-8 BDEFHIJKL
2(3H)-one 942 Ethyl (2Z,4E)-deca-2,4-dienoate 3025-30-7 BDEFHJK 943
Pelargene 68039-40-7 DEFHJK 945 2-cyclohexylidene-2- 10461-98-0
DFHJK phenylacetonitrile 946 Perillaldehyde 2111-75-3 ACHIJK 947
Perillyl acetate 15111-96-3 DFHJK 948 Perillyl alcohol 536-59-4
CHIJK 950 (2-isopropoxyethyl)benzene 68039-47-4 ACEFHJKL 951 Ethyl
(2Z,4E)-deca-2,4-dienoate 313973-37-4 BDEFHJK 953
(2-(cyclohexyloxy)ethyl)benzene 80858-47-5 DEFHJK 954 Phenethyl
2-methylbutyrate 24817-51-4 DEFHJK 955 Phenethyl alcohol 60-12-8
BCEFGIK 959 Phenethyl phenylacetate 102-20-5 DHJ 962 Phenoxanol
55066-48-3 DEFHJK 965 Phenyl benzoate 93-99-2 DFHJK 967 Phenyl
ethyl benzoate 94-47-3 DHJ 969 Phenylacetaldehyde ethyleneglycol
101-49-5 BCEFGIK acetal 973 2-(6,6-dimethylbicyclo[3.1.1]hept-2-
30897-75-7 ACFHIJKL en-2-yl)acetaldehyde 974 Pinocarveol 5947-36-4
BCEFGIJKL 976 Piperonyl acetone 55418-52-5 CEFGJ 978
3a,4,5,6,7,7a-hexahydro-1H-4,7- 68039-44-1 DEFHJK methanoinden-6-yl
pivalate 980 (4aR,8aS)-7-methyloctahydro-1,4- 41724-19-0 CEFGJKL
methanonaphthalen-6(2H)-one 982 p-Menth-3-en-1-ol 586-82-3 BCGIJK
985 (E)-3,3-dimethyl-5-(2,2,3- 107898-54-4 DHJK
trimethylcyclopent-3-en-1-yl)pent-4- en-2-ol 988
1-methyl-4-(4-methylpent-3-en-1- 52474-60-9 DFHJK
yl)cyclohex-3-ene-1-carbaldehyde 993 Propylene glycol 57-55-6
ACEFGIKL 998 p-Tolyl phenylacetate 101-94-0 DFHJ 1000 Ethyl
2,4,7-decatrienoate 78417-28-4 BDEFHJK 1003
2-benzyl-4,4,6-trimethyl-1,3-dioxane 67633-94-7 DEFHJK 1006
2,4-dimethyl-4- 82461-14-1 BDEFHJK phenyltetrahydrofuran 1007
(2R,4a'R,8a'R)-3,7'-dimethyl- 41816-03-9 DEFHJK
3',4',4a',5',8',8a'-hexahydro-1'H- spiro[oxirane-2,2'-
[1,4]methanonaphthalene] 1008 (Z)-6-ethylideneoctahydro-2H-5,8-
93939-86-7 BCEFHJKL methanochromene 1009 2-((S)-1-((S)-3,3-
236391-76-7 DFHJ dimethylcyclohexyl)ethoxy)-2- oxoethyl propionate
1010 Methyl 2,2-dimethyl-6- 81752-87-6 ADHIJKL
methylenecyclohexane-1-carboxylate 1012
2-methyl-5-phenylpentan-1-ol 25634-93-9 DEFHJK 1016
4-methyl-2-phenyl-3,6-dihydro-2H- 60335-71-9 BCEFGJK pyran 1020
Sabinol 471-16-9 BCEFHIJKL 1021 Safrole 94-59-7 BCEFHK 1022
2,2,7,9-tetramethylspiro(5.5)undec- 502847-01-0 DHIJK 8-en-1-one
1023 3-methyl-5-(2,2,3- 65113-99-7 DEFHJK
trimethylcyclopent-3-en-1-yl)pentan- 2-ol 1024
(Z)-2-ethyl-4-(2,2,3- 28219-61-6 DEFHJK
trimethylcyclopent-3-en-1-yl)but-2- en-1-ol 1025
(E)-2-methyl-4-(2,2,3- 28219-60-5 CHJK
trimethylcyclopent-3-en-1-yl)but-2- en-1-ol 1026
5-methoxyoctahydro-1H-4,7- 86803-90-9 CHJK
methanoindene-2-carbaldehyde 1027 5-methoxyoctahydro-1H-4,7-
193425-86-4 CHJK methanoindene-2-carbaldehyde 1028 Sclareol
515-03-7 DEFHJ 1029 Sclareol oxide 5153-92-4 DEFHJK 1031
Selina-3,7(11)-diene 6813-21-4 DEFHJKL 1032 2-(1-(3,3- 477218-42-1
DEFHJ dimethylcyclohexyl)ethoxy)-2- methylpropyl
cyclopropanecarboxylate 1033 3-(4-isobutylphenyl)-2- 6658-48-6 DHJK
methylpropanal 1035 Spathulenol 6750-60-3 DEFHJK 1036 Spirambrene
533925-08-5 BCEFHJK
1037 Spirodecane 6413-26-9 BCEFGIJKL 1038
1-(spiro[4.5]dec-7-en-7-yl)pent-4-en- 224031-70-3 DGJK 1-one 1042
2-(4-methylthiazol-5-yl)ethan-1-ol 137-00-8 CGIKL 1043
2-(heptan-3-yl)-1,3-dioxolane 4359-47-1 ACEFHIJKL 1045
(Z)-dodec-4-enal 21944-98-9 BDFHJK 1046 tau-Cadinol 5937-11-1
DEFHJK 1047 tau-Muurolol 19912-62-0 DEFHJK 1053 Tetrahydrojasmone
13074-63-0 BDFHIJKL 1057 2,6,10,10-tetramethyl-1- 36431-72-8
BDFHIJKL oxaspiro[4.5]dec-6-ene 1059 Thiomenthone 38462-22-5
BDEFHIJKL 1060 Thujopsene 470-40-6 BDEFGJKL 1062 Thymol methyl
ether 1076-56-8 ADHIJKL 1063 1-(2,2,6-trimethylcyclohexyl)hexan-
70788-30-6 DEFHJK 3-ol 1064 trans,trans-2,4-Nonadienal 5910-87-2
ACHKL 1065 trans,trans-Farnesol 106-28-5 DEFHJK 1066
trans-2,cis-6-Nonadienal 557-48-2 ACHKL 1067 trans-2-Decenal
3913-81-3 ADHKL 1070 trans-2-Nonen-1-al 18829-56-6 ADHKL 1072
trans-3, cis-6-nonadienol 56805-23-3 ACEFHK 1073 trans-4-Decen-1-al
65405-70-1 ADHKL 1075 trans-ambrettolide 51155-12-5 DGJ 1077
trans-beta-ocimene 13877-91-3 ADGIKL 1078 trans-beta-Ocimene
3779-61-1 ADGIKL 1082 trans-Geraniol 106-24-1 BCHIK 1083
trans-Hedione 2570-03-8 DFHJK 1085 7-(1,1-Dimethylethyl)-2H-1,5-
195251-91-3 CEFHJ benzodioxepin-3(4H)-one 1089 Tricyclone
68433-81-8 DEFHJK 1090 Tridecyl alcohol 112-70-9 DEFGJK 1091
Triethyl citrate 77-93-0 CEFGJ 1093 Methyl 2-((1-hydroxy-3-
144761-91-1 DFHJ phenylbutyl)amino)benzoate 1095
1-((2E,5Z,9Z)-2,6,10- 28371-99-5 DHJK
trimethylcyclododeca-2,5,9-trien-1- yl)ethan-1-one 1097
Decahydro-2,6,6,7,8,8-hexamethyl- 338735-71-0 BDEFHJK
2h-indeno(4,5-b)furan 1099 13-methyl oxacyclopentadec-10-en-
365411-50-3 DEFHJK 2-one 1102 Undecanal 112-44-7 BDHJK 1104
(E)-4-methyldec-3-en-5-ol 81782-77-6 BDEFHIJK 1105 Valencene
4630-07-3 BDEFHJK 1107 Valerianol 20489-45-6 DEFHJK 1111 Vanillin
isobutyrate 20665-85-4 CHJ 1113 Vaniwhite .RTM. 5533-03-9 CGIK 1116
(Z)-2-methyl-4-(2,6,6- 68555-62-4 BDFHJK
trimethylcyclohex-2-en-1-yl)but-2- enal 1117 Methyl
2,4-dihydroxy-3,6- 4707-47-5 CGIJ dimethylbenzoate 1120
1-methoxy-3a,4,5,6,7,7a-hexahydro- 27135-90-6 ACEFHJKL
1H-4,7-methanoindene 1121 Methyl (Z)-2-((3-(4-(tert- 91-51-0 DFHJ
butyl)phenyl)-2- methylpropylidene)amino)benzoate 1125
(Z)-hex-3-en-1-yl isobutyrate 41519-23-7 ADEFHJKL 1126 Vertacetal
5182-36-5 BCFHJK 1129 1-((3R,3aR,7R,8aS)-3,6,8,8- 32388-55-9 DHJK
tetramethyl-2,3,4,7,8,8a-hexahydro-
1H-3a,7-methanoazulen-5-yl)ethan- 1-one 1131 Methyl (Z)-2-(((2,4-
68738-99-8 DEFHJ dimethylcyclohex-3-en-1-
yl)methylene)amino)benzoate 1135 Vetiverol 89-88-3 CEFHIJK 1136
Vetivert Acetate 117-98-6 DEFHJK 1137
Decahydro-3H-spiro[furan-2,5'- 68480-11-5 DEFGJKL
[4,7]methanoindene] 1138 (2Z,6E)-nona-2,6-dienenitrile 67019-89-0
ACEFHKL 1139 (Z)-cyclooct-4-en-1-yl methyl 87731-18-8 BCHJKL
carbonate 1140 (1aR,4S,4aS,7R,7aS,7bS)-1,1,4,7- 552-02-3 DEFHJK
tetramethyldecahydro-1H- cyclopropa[e]azulen-4-ol 1142
3,5,5,6,7,8,8-heptamethyl-5,6,7,8- 127459-79-4 DHJ
tetrahydronaphthalene-2-carbonitrile 1143 (1S,2S,3S,5R)-2,6,6-
133636-82-5 DEFHJK trimethylspiro[bicyclo[3.1.1]heptane-
3,1'-cyclohexan]-2'-en-4'-one 1144
1',1',5',5'-tetramethylhexahydro- 154171-76-3 DEFHJK
2'H,5'H-spiro[[1,3]dioxolane-2,8'- [2,4a]methanonaphthalene] 1145
1',1',5',5'-tetramethylhexahydro- 154171-77-4 DEFHJK
2'H,5'H-spiro[[1,3]dioxolane-2,8'- [2,4a]methanonaphthalene] K 1146
4-(4-hydroxy-3- 122-48-5 CEFGJ methoxyphenyl)butan-2-one 1147
(1R,8aR)-4-isopropyl-1,6-dimethyl- 41929-05-9 DEFHJKL
1,2,3,7,8,8a-hexahydronaphthalene 1148
4,5-epoxy-4,11,11-trimethyl-8- 1139-30-6 DEFHJK
methylenebicyclo(7.2.0)undecane 1149
1,3,4,6,7,8alpha-hexahydro-1,1,5,5- 23787-90-8 DEFHIJK
tetramethyl-2H-2,4alpha- methanophthalen-8(5H)-one
TABLE-US-00003 TABLE 2 List of materials with at least one MORV
greater than 5 to 10 Num- CAS Comment ber Material Name Number Code
2 2,4-dimethyl-2-(5,5,8,8-tetramethyl- 131812-67-4 DFHJ
5,6,7,8-tetrahydronaphthalen-2-yl)- 1,3-dioxolane 23
3a,5,6,7,8,8b-hexahydro- 823178-41-2 DEFHJK
2,2,6,6,7,8,8-heptamethyl-4H- indeno(4,5-d)-1,3-dioxole 141
2,4-dimethyl-4,4a,5,9b- 27606-09-3 CEFHJK
tetrahydroindeno[1,2-d][1,3]dioxine 185 (1-methyl-2-((1,2,2-
198404-98-7 DEFHJK trimethylbicyclo[3.1.0]hexan-3-
yl)methyl)cyclopropyl)methanol 227 Isobornylcyclohexanol 68877-29-2
DEFHJK 230 Isobornyl cyclohexanol 66072-32-0 DEFHJK 246
Indol/Hydroxycitronellal Schiff base 67801-36-9 DEFHJ 248
Hydroxymethyl isolongifolene 59056-64-3 DEFHJK 343
8,8-dimethyl-3a,4,5,6,7,7a- 76842-49-4 DEFHJK
hexahydro-1H-4,7-methanoinden-6- yl propionate 359
(E)-4-((3aR,4R,7R,7aR)- 501929-47-1 DEFHJK
1,3a,4,6,7,7a-hexahydro-5H-4,7- methanoinden-5-ylidene)-3-
methylbutan-2-ol 565 Cedryl methyl ether 19870-74-7 BDEFHJK 631
beta-Copaene 18252-44-3 BDEFHJKL 659 2'-isopropyl-1,7,7-
869292-93-3 BDEFHJK trimethylspiro[bicyclo[2.2.1]heptane-
2,4'-[1,3]dioxane] 674 (4aR,5R,7aS,9R)-2,2,5,8,8,9a- 211299-54-6
DEFHJK hexamethyloctahydro-4H-4a,9-
methanoazuleno[5,6-d][1,3]dioxole 678
(3S,5aR,7aS,11aS,11bR)-3,8,8,11a- 57345-19-4 DEFHJ
tetramethyldodecahydro-5H-3,5a- epoxynaphtho[2,1-c]oxepine 679
2,2,6,6,7,8,8-heptamethyldecahydro- 476332-65-7 DEFHJK
2H-indeno[4,5-b]furan 715 alpha-Cedrene epoxide 13567-39-0 BDEFHJK
758 Acetoxymethyl-isolongifolene 59056-62-1 DEFHJK (isomers) 1028
Sclareol 515-03-7 DEFHJ 1097 Decahydro-2,6,6,7,8,8-hexamethyl-
338735-71-0 DEFHJK 2h-indeno(4,5-b)furan
TABLE-US-00004 TABLE 3 List of materials with at least one MORV
from 0.5 to less than 1 Num- CAS Comment ber Material Name Number
Code 12 1-ethoxy-4-(tert- 181258-89-9 ADEFHJK pentyl)cyclohexane 19
(3Z)-1-(2-buten-1-yloxy)-3- 888744-18-1 ADEFHJKL hexene 20
4-(2-methoxypropan-2-yl)-1- 14576-08-0 ADHIJKL methylcyclohex-1-ene
24 O-Methyl linalool 60763-44-2 ADHIJKL 26 o-Methoxycinnamaldehyde
1504-74-1 ACHK 27 Octanal, 3,7-dimethyl- 25795-46-4 ADGIJKL 53
3,3-Dimethyl-5(2,2,3- 329925-33-9 CEFHJ Trimethyl-3-Cyclopenten-
1yl)-4-Penten-2-ol 54 n-Hexyl salicylate 6259-76-3 DEFHJ 55 n-Hexyl
2-butenoate 19089-92-0 ADEFHJKL 59 Neryl Formate 2142-94-1 BCEFHJK
72 Methyl-beta-ionone 127-43-5 DHJK 73 Myroxide 28977-57-3 ADGIJKL
81 (E)-3,7-dimethylocta-4,6- 18479-54-4 BCEFGIJK dien-3-ol 84
(Z)-hex-3-en-1-yl 188570-78-7 BCEFHIKL cyclopropanecarboxylate 96
Methyl phenyl carbinyl 120-45-6 BCHJK propionate 97 Methyl
phenylacetate 101-41-7 ACEFHIKL 107 2-methyl-6- 91069-37-3 BCEFGIKL
oxaspiro[4.5]decan-7-one 111 Methyl geraniate 2349-14-6 BCHJKL 115
2-ethoxy-4- 5595-79-9 CFGK (methoxymethyl)phenol 116 Methyl
40203-73-4 ACEFHIKL cyclopentylideneacetate 125 Methoxymelonal
62439-41-2 ACGIJK 133 ((1s,4s)-4- 13828-37-0 BDEFHIJK
isopropylcyclohexyl)methanol 147 Linalyl propionate 144-39-8 BDFHJK
150 Linalyl formate 115-99-1 ACFHJK 151 Linalyl butyrate 78-36-4
BDEFHJK 154 Linalyl acetate 115-95-7 BDHJK 157 Linalool 78-70-6
BCEFGIJK 163 (Z)-hex-3-en-1-yl methyl 67633-96-9 ACEFGKL carbonate
166 Lepidine 491-35-0 BCEFHIKL 169 L-Carvone 6485-40-1 ACGIJKL 181
Khusinil 75490-39-0 DHJK 191 Isoraldeine 1335-46-2 BDHIJK 194
Isopropylvinylcarbinol 4798-45-2 ACGIKL 198 Isopropyl
2-methylbutyrate 66576-71-4 ACEFGIJKL 201 Isopentyrate 80118-06-5
ADEFGIJKL 204 Isononyl acetate 40379-24-6 BDEFHJKL 205 Isononanol
27458-94-2 BDEFGIKL 213 Isoeugenyl acetate 93-29-8 CFHJK 214
Isoeugenol 97-54-1 CEFHIK 232 Isoborneol 124-76-5 ACEFHIJKL 237
Isoamyl octanoate 2035-99-6 DEFHJK 239 Isoamyl isobutyrate
2050-01-3 ACEFGIJKL 255 Hydrocinnamic acid 501-52-0 CEFHIK 258
Hydratopic alcohol 1123-85-9 BCEFHIK 264 Hexyl propanoate 2445-76-3
ADEFHIKL 270 Hexyl butyrate 2639-63-6 BDEFHJKL 273 Hexyl
2-methylbutanoate 10032-15-2 BDEFHJKL 275 Hexyl 2-furoate
39251-86-0 DEFHJK 282 Heptyl alcohol 111-70-6 ACEFGIKL 283 Heptyl
acetate 112-06-1 ADEFHKL 284 Heptaldehyde 111-71-7 ACHIKL 287
Heliotropin 120-57-0 BCGIK 302 Geranyl nitrile 5146-66-7 BCEFHKL
306 Geranyl formate 105-86-2 BCEFHJK 308 Geranyl caprylate
51532-26-4 DEFHJ 310 Geranyl benzoate 94-48-4 DFHJ 312 Geranial
141-27-5 ACHIKL 314 N,2-dimethyl-N- 84434-18-4 BCEFHJK
phenylbutanamide 319 gamma-Terpinene 99-85-4 ADEFGIJKL 346
2-(sec-butyl)cyclohexan-1- 14765-30-1 ADFHIKL one 354
3-(2-ethylphenyl)-2,2- 67634-14-4 BDHJK dimethylpropanal 355
2-(tert-butyl)cyclohexyl ethyl 67801-64-3 BDFHJK carbonate 365
2-(tert-butyl)cyclohexyl ethyl 81925-81-7 ACFHIKL carbonate 366
Fenchyl alcohol 1632-73-1 ACGIJKL 376 Eucalyptol 470-82-6 ADEFGIJKL
379 Ethyl vanillin acetate 72207-94-4 CHJ 387 Ethyl octanoate
106-32-1 BDEFHJKL 400 Ethyl cinnamate 103-36-6 BCEFHK 412 Ethyl 2-
2511-00-4 BDFHIJKL (cyclohexyl)propionate 419
d-p-8(9)-Menthen-2-one 5524-05-0 ACGIJKL 420
4-methyl-2-phenyltetrahydro- 94201-73-7 BDEFHJK 2H-pyran 437
Dihydromyrcenol 18479-58-8 ADEFGIJK 438 Dihydrojasmone 1128-08-1
BCFHIJKL 439 Dihydroisophorone 873-94-9 ACEFGIJKL 440
Dihydroeugenol 2785-87-7 CEFHIJK 442 Dihydrocoumarin 119-84-6
BCGIKL 443 Dihydrocarvone 7764-50-3 ACGIJKL 447
Dihydro-alpha-terpinyl 80-25-1 BDEFHIJKL acetate 448
Dihydro-alpha-ionone 31499-72-6 BDHIJK 454 Dibenzyl ether 103-50-4
DEFHJK 455 Dibutyl o-phthalate 84-74-2 DEFHJ 469
2-pentylcyclopentan-1-one 4819-67-4 BDFHIKL 472 Decyl anthranilate
18189-07-6 DEFHJ 477 Methyl (1s,4s)-1,4- 23059-38-3 ADEFHIJKL
dimethylcyclohexane-1- carboxylate 481 Cyclohexylethyl acetate
21722-83-8 BDEFHJKL 492 Creosol 93-51-6 BCHIK 495 Cosmene 460-01-5
ADEFGIKL 496 4-cyclohexyl-2-methylbutan- 83926-73-2 BDEFGIJK 2-ol
504 2-benzyl-2-methylbut-3- 97384-48-0 BDHJK enenitrile 509
Citronellyl nitrile 51566-62-2 BCEFGIKL 510 Citronellyl
phenylacetate 139-70-8 DFHJ 512 Citronellyl formate 105-85-1
BCEFGJKL 515 Citronellyl benzoate 10482-77-6 DFHJ 517 Citronellol
106-22-9 BCHIJKL 518 Citronellal 106-23-0 ACHIJKL 522 Citral
5392-40-5 ACHIKL 525 cis-Pinane 6876-13-7 ADEFGIJKL 526
(Z)-3-methyl-2-(pent-2-en-1- 488-10-8 BCHIJKL
yl)cyclopent-2-en-1-one 528 cis-iso-Eugenol 5912-86-7 CEFHIK 535
cis-3-Hexenyl valerate 35852-46-1 BDEFHJKL 536 cis-3-Hexenyl
tiglate 67883-79-8 BDEFHJK 538 cis-3-Hexenyl propionate 33467-74-2
ACEFHIKL 540 cis-3-Hexenyl butyrate 16491-36-4 ADEFHJKL 542
cis-3-Hexen-1-ol 928-96-1 ACEFHIKL 547 cis-2-Hexenol 928-94-9
ACEFHIKL 549 Cinnamyl nitrile 4360-47-8 ACEFGIK 554 Cinnamic
aldehyde 104-55-2 ACHIK 556 Cinnamyl nitrile 1885-38-7 ACEFGIK 557
Chloroxylenol 88-04-0 BCHIJK 575 Carvacrol 499-75-2 DHIJK 576
Carvone 99-49-0 ACGIJKL 579 Carbitol 111-90-0 BCEFGIK 583 Caproyl
alcohol 111-27-3 ACEFGIKL 585 2-(2,2,3-trimethylcyclopent-3-
15373-31-6 ACGIJKL en-1-yl)acetonitrile 588 Camphor 76-22-2
ACEFGIJKL 602 (E)-2-methyl-4-(2,6,6- 3155-71-3 DHJK
trimethylcyclohex-1-en-1- yl)but-2-enal 605 Borneol 507-70-0
ACEFHIJKL 617 beta-Pinene epoxide 6931-54-0 ACEFGIJKL 619
beta-Phellandrene 555-10-2 ADEFGIJKL 640 Benzylacetone 2550-26-7
ACEFGIK 641 Benzyl salicylate 118-58-1 DFGJ 645 Benzyl isovalerate
103-38-8 BDEFHJK 647 Benzyl isobutyrate 103-28-6 BCHJK 651 Benzyl
butyrate 103-37-7 BCEFHJK 652 Benzyl alcohol 100-51-6 ACEFGIKL 662
1-(3,3- 25225-08-5 ADEFHIJKL dimethylcyclohexyl)ethyl formate 664
Anisyl acetate 104-21-2 BCEFGK 665 Anisyl formate 122-91-8 BCEFGK
667 Anethole 104-46-1 ACEFHK 672 Amyl benzoate 2049-96-9 DEFHJK 687
alpha-Terpinyl acetate 80-26-2 BDHJK 699 alpha-methyl- 10528-67-3
BDEFHIK cyclohexanepropanol 701 alpha-methyl cinnamaldehyde
101-39-3 ACHIK 703 alpha-Isomethylionone 127-51-5 BDHIJK 740
2,5-Dimethyl-4-methoxy- 4077-47-8 ACEFGIJKL 3(2H)-furanone 743
Allyl phenoxyacetate 7493-74-5 BCGK 744 Allyl Phenethyl ether
14289-65-7 ACEFHK 745 Allyl heptanoate 142-19-8 ADEFHJKL 755
N-ethyl-N-(m- 179911-08-1 CEFHJK tolyl)propionamide 760
3-hydroxybutan-2-one 513-86-0 ACEFGIKL 761 Acetoanisole 100-06-1
BCEFHIK 777 6-Methylquinoline 91-62-3 BCEFHIKL 779
6,8-Diethyl-2-nonanol 70214-77-6 BDEFGIJKL 784 5-Methyl-3-heptanone
541-85-5 ACFGIKL 789 4-Vinylphenol 2628-17-3 BCHIK 796
4-hydroxy-3-methoxy- 458-36-6 CH cinnamaldehyde 797 4-Ethylguaiacol
2785-89-9 CEFHIK 799 4-Damascol 4927-36-0 BDFHJK 808
3-methyl-4-phenylpyrazole 13788-84-6 CEFHK 810 3-Methyl-1,2-
765-70-8 ACEFGIKL cyclopentanedione 811 3-Methoxy-5-methylphenol
3209-13-0 BCHIK 812 3-Methoxy-3-Methyl Butanol 56539-66-3 ACGIKL
817 3-Hexenol 544-12-7 ACEFHIKL 819 3,7-dimethyl-2-methylene-6-
22418-66-2 ADFHIJK octenal 820 3,7-dimethyl-1-octanol 106-21-8
BDEFGIJKL 832 2-Phenylethyl acetate 103-45-7 BCEFHK 835 2-Phenethyl
propionate 122-70-3 BCEFHJK 836 2-Pentylcyclopentan-1-ol 84560-00-9
DEFHIKL 838 2-nonanone propylene glycol 165191-91-3 BDEFHJK acetal
845 2-Methoxy-3-(1- 24168-70-5 BCEFGIK methylpropyl)pyrazine 846
2-isopropyl-N,2,3- 51115-67-4 ACEFGIJK trimethylbutyramide 847
2-Isopropyl-5-methyl-2- 35158-25-9 ADFGIJKL hexenal 848
2-Isopropyl-4-methylthiazole 15679-13-7 ACHIJKL 851 2-Hexen-1-ol
2305-21-7 ACEFHIKL 858 2-Butoxyethanol 111-76-2 ACEFGIKL 875
1,4-Cineole 470-67-7 ADGIJKL 880 1-(2,6,6-Trimethyl-2- 43052-87-5
BDHIJK cyclohexen-1-yl)-2-buten-1-one 882 (Z)-3-hepten-1-yl acetate
1576-78-9 ACEFHKL 883 (S)-(1R,5R)-4,6,6- 1196-01-6 ACEFGIJKL
trimethylbicyclo[3.1.1]hept-3- en-2-one 888 (R)-(-)-Linalool
126-91-0 BCEFGIJK 889 (l)-Citronellal 5949-05-3 ACHIJKL 891
(d)-Citronellal 2385-77-5 ACHIJKL 899 (+)-Citronellol 1117-61-9
BCHIJKL 900 (-)-Citronellol 7540-51-4 BCHIJKL 901 (+)-alpha-Pinene
7785-70-8 ADEFGIJKL 902 (+)-Carvone 2244-16-8 ACGIJKL 903
(-)-alpha-Pinene 7785-26-4 ADEFGIJKL 904 Methyl 2-methylbutyrate
868-57-5 ACEFGIKL 909 Hexyl tiglate 16930-96-4 BDEFHJKL 918 Allyl
2- 68901-15-5 CHJK (cyclohexyloxy)acetate 921 1,5- 75147-23-8
CFHIJK dimethylbicyclo[3.2.1]octan- 8-one oxime 931
alpha-acetoxystyrene 2206-94-2 ACEFHIK 940 p-Cymene 99-87-6 ADGIJKL
956 Phenethyl formate 104-62-1 ACEFHK 958 Phenethyl isobutyrate
103-48-0 DHJK 960 Phenethyl tiglate 55719-85-2 DHJK 971 Phenylethyl
methacrylate 3683-12-3 DHJK 977 p- 4395-92-0 BDFHK
Isopropylphenylacetaldehyde 981 1,2-dimethyl-3-(prop-1-en-2-
72402-00-7 BCEFGIJKL yl)cyclopentan-1-ol 983 p-Methoxyphenylacetone
122-84-9 BCEFHK 986 (2Z,5Z)-5,6,7-trimethylocta- 358331-95-0
ADHIJKL 2,5-dien-4-one 987 p-Propyl anisole 104-45-0 ADEFHKL 994
p-t-butyl phenyl acetaldehyde 109347-45-7 BDHJK 995 p-tert-Amyl
cyclohexanol 5349-51-9 BDEFHIJK
1001 Racemic alpha-Pinene 80-56-8 ADEFGIJKL 1002
4-(4-hydroxyphenyl)butan-2- 5471-51-2 CEFGIK one 1004 Rhodinol
141-25-3 BCHIJKL 1005 Ethyl (2,3,6- 93981-50-1 BDEFHJKL
trimethylcyclohexyl) carbonate 1011 1-(3,3- 25225-10-9 ADHIJKL
dimethylcyclohexyl)ethyl acetate 1017 S)-(+)-Linalool 126-90-9
BCEFGIJK 1018 Sabinene 3387-41-5 ADEFGIJKL 1019 Sabinene hydrate
546-79-2 ADEFGIJKL 1030 Propyl (S)-2-(tert- 319002-92-1 BDEFHJK
pentyloxy)propanoate 1039 Spirolide 699-61-6 BCGIKL 1040
(Z)-5-methylheptan-3-one 22457-23-4 BCEFGIJKL oxime 1041
1-phenylethyl acetate 93-92-5 ACEFHIK 1051 Tetrahydrogeranial
5988-91-0 ADGIJKL 1052 Tetrahydroionol 4361-23-3 BDEFHIJK 1054
Tetrahydrolinalool 78-69-3 BDEFGIJKL 1055 Tetrahydrolinalyl acetate
20780-48-7 ADEFHJKL 1058 Ethyl (1R,6S)-2,2,6- 22471-55-2 ADEFHIJKL
trimethylcyclohexane-1- carboxylate 1061 Thymol 89-83-8 BDHIJK 1069
trans-2-Hexenol 928-95-0 ACEFHIKL 1071 trans-2-tert- 5448-22-6
ACGIJKL Butylcyclohexanol 1074 trans-alpha-Damascone 24720-09-0
BDHIJK 1076 trans-Anethole 4180-23-8 ACEFHK 1079 trans-Cinnamic
acid 140-10-3 CEFHK 1081 trans-Dihydrocarvone 5948-04-9 ACGIJKL
1084 trans-Isoeugenol 5932-68-3 CEFHIK 1088 Trichloromethyl phenyl
90-17-5 BDEFGJ carbinyl acetate 1098 2-mercapto-2-methylpentan-
258823-39-1 ACEFHIJKL 1-ol 1110 Vanillin acetate 881-68-5 CH 1112
Vanitrope 94-86-0 CEFHK 1115 2,2,5-trimethyl-5- 65443-14-3 BDFGIJKL
pentylcyclopentan-1-one 1118 Veratraldehyde 120-14-9 BCGIK 1119
(1R,5R)-4,6,6- 18309-32-5 ACEFGIJKL trimethylbicyclo[3.1.1]hept-3-
en-2-one 1122 Verdol 13491-79-7 ACGIJKL 1127
4-(tert-butyl)cyclohexyl 10411-92-4 BDEFHJK acetate 1128
4-(tert-butyl)cyclohexyl 32210-23-4 BDEFHJK acetate 1133 Vethymine
7193-87-5 CEFGK 1134 4-methyl-4-phenylpentan-2-yl 68083-58-9 BDFHJK
acetate 1141 (Z)-1-((2- 292605-05-1 ADEFHKL
methylallyl)oxy)hex-3-ene
TABLE-US-00005 TABLE 4 List of materials with ALL MORVs from 1 to 5
Num- CAS Comment ber Material Name Number Code 7
3-methoxy-7,7-dimethyl-10- 216970-21-7 BDEFHJK
methylenebicyclo[4.3.1]decane 14 Oxyoctaline formate 65405-72-3
DFHJK 39 2,2,6,8-tetramethyl-1,2,3,4,4a,5,8,8a- 103614-86-4 DEFHIJK
octahydronaphthalen-1-ol 48 Nootkatone 4674-50-4 DHJK 183 Khusimol
16223-63-5 CEFHJK 199 Isopimpinellin 482-27-9 CFGJ 206
Iso3-methylcyclopentadecan-1-one 3100-36-5 DEFGJK 212 Isoeugenyl
benzyl ether 120-11-6 DFHJ 215 1-((2S,3S)-2,3,8,8-tetramethyl-
54464-57-2 DHJK 1,2,3,4,5,6,7,8-octahydronaphthalen-
2-yl)ethan-1-one 229 Isobornyl isobutyrate 85586-67-0 BDEFHIJK 260
2,3-dihydro-3,3-dimethyl-1H-indene- 173445-44-8 DHJK 5-propanal 261
3-(3,3-dimethyl-2,3-dihydro-1H- 173445-65-3 DHJK
inden-5-yl)propanal 281 3a,4,5,6,7,7a-hexahydro-1H-4,7- 5413-60-5
CEFGJK methanoinden-6-yl acetate 329 gamma-Eudesmol 1209-71-8 DFHJK
335 4,6,6,7,8,8-hexamethyl-1,3,4,6,7,8- 1222-05-5 DEFHJK
hexahydrocyclopenta[g]isochromene 353
(Z)-6-ethylideneoctahydro-2H-5,8- 69486-14-2 CEFGJK
methanochromen-2-one 360 8,8-dimethyl-3a,4,5,6,7,7a- 171102-41-3
DEFHJK hexahydro-1H-4,7-methanoinden-6- yl acetate 441
Octahydro-1H-4,7-methanoinden-5- 64001-15-6 DEFHJKL yl acetate 484
3a,4,5,6,7,7a-hexahydro-1H-4,7- 113889-23-9 DEFHJK
methanoinden-6-yl butyrate 487 3a,4,5,6,7,7a-hexahydro-1H-4,7-
67634-20-2 DEFHJK methanoinden-5-yl isobutyrate 488 Curzerene
17910-09-7 DHJK 501 (E)-cycloheptadec-9-en-1-one 542-46-1 DEFGJ 566
Cedryl formate 39900-38-4 BDEFHJK 567 Cedryl acetate 77-54-3 DEFHJK
569 Cedrol 77-53-2 DEFHJK 570 5-methyl-1-(2,2,3- 139539-66-5 DEFHJK
trimethylcyclopent-3-en-1-yl)-6- oxabicyclo[3.2.1]octane 573
Caryophyllene alcohol acetate 32214-91-8 DEFHJK 574 Caryolan-1-ol
472-97-9 DEFHJK 603 Bornyl isobutyrate 24717-86-0 BDEFHIJK 616
beta-Santalol 77-42-9 DEFHJK 621 beta-Patchoulline 514-51-2
BDEFGJKL 624 beta-Himachalene Oxide 57819-73-5 BDFHJK 627
(2,2-dimethoxyethyl)benzene 101-48-4 DHJK 632 beta-Cedrene 546-28-1
BDEFGJKL 663 Anisyl phenylacetate 102-17-0 DFHJ 680
2,2,6,6,7,8,8-heptamethyldecahydro- 647828-16-8 ADEFHJK
2H-indeno[4,5-b]furan 684 alpha-Vetivone 15764-04-2 DHJK 694
alpha-Santalol 115-71-9 DEFHJK 696 alpha-Patchoulene 560-32-7
ADEFHJKL 708 alpha-Gurjunene 489-40-7 BDEFHJKL 712 alpha-Eudesmol
473-16-5 DEFHJK 714 alpha-Cubebene 17699-14-8 ADEFHJKL 726
alpha-Agarofuran 5956-12-7 BDEFHJK 750 Allo-aromadendrene
25246-27-9 BDEFHJKL 764 Acetarolle .RTM. 744266-61-3 DFHJK 775
7-eip-alpha-Eudesmol 123123-38-6 DEFHJK 776 7-Acetyl-1,1,3,4,4,6-
1506-02-1 DEFHJ hexamethyltetralin 788 5-Cyclohexadecenone
37609-25-9 DEFGJK 804 3-Thujopsanone 25966-79-4 BDEFHJK 872
10-epi-gamma-Eudesmol 15051-81-7 DFHJK 919
3a,4,5,6,7,7a-hexahydro-1H-4,7- 17511-60-3 CEFHJK methanoinden-6-yl
propionate 927 5-Acetyl-1,1,2,3,3,6- 15323-35-0 DEFHJK
hexamethylindan 933 Patchouli alcohol 5986-55-0 DEFHIJK 978
3a,4,5,6,7,7a-hexahydro-1H-4,7- 68039-44-1 DEFHJK methanoinden-6-yl
pivalate 1007 (2R,4a'R,8a'R)-3,7'-dimethyl- 41816-03-9 DEFHJK
3',4',4a',5',8',8a'-hexahydro-1'H- spiro[oxirane-2,2'-
[1,4]methanonaphthalene] 1022 2,2,7,9-tetramethylspiro(5.5)undec-
502847-01-0 DHIJK 8-en-1-one 1024 (Z)-2-ethyl-4-(2,2,3- 28219-61-6
DEFHJK trimethylcyclopent-3-en-1-yl)but-2- en-1-ol 1027
5-methoxyoctahydro-1H-4,7- 193425-86-4 CHJK
methanoindene-2-carbaldehyde 1029 Sclareol oxide 5153-92-4 DEFHJK
1035 Spathulenol 6750-60-3 DEFHJK 1038
1-(spiro[4.5]dec-7-en-7-yl)pent-4-en- 224031-70-3 DGJK 1-one 1060
Thujopsene 470-40-6 BDEFGJKL 1089 Tricyclone 68433-81-8 DEFHJK 1107
Valerianol 20489-45-6 DEFHJK 1129 1-((3R,3aR,7R,8aS)-3,6,8,8-
32388-55-9 DHJK tetramethyl-2,3,4,7,8,8a-hexahydro-
1H-3a,7-methanoazulen-5-yl)ethan- 1-one 1131 Methyl (Z)-2-(((2,4-
68738-99-8 DEFHJ dimethylcyclohex-3-en-1-
yl)methylene)amino)benzoate 1136 Vetivert Acetate 117-98-6 DEFHJK
1137 Decahydro-3H-spiro[furan-2,5'- 68480-11-5 DEFGJKL
[4,7]methanoindene] 1140 (1aR,4S,4aS,7R,7aS,7bS)-1,1,4,7- 552-02-3
DEFHJK tetramethyldecahydro-1H- cyclopropa[e]azulen-4-ol 1142
3,5,5,6,7,8,8-heptamethyl-5,6,7,8- 127459-79-4 DHJ
tetrahydronaphthalene-2-carbonitrile 1143 (1S,2S,3S,5R)-2,6,6-
133636-82-5 DEFHJK trimethylspiro[bicyclo[3.1.1]heptane-
3,1'-cyclohexan]-2'-en-4'-one 1144
1',1',5',5'-tetramethylhexahydro- 154171-76-3 DEFHJK
2'H,5'H-spiro[[1,3]dioxolane-2,8'- [2,4a]methanonaphthalene] 1145
1',1',5',5'-tetramethylhexahydro- 154171-77-4 DEFHJK
2'H,5'H-spiro[[1,3]dioxolane-2,8'- [2,4a]methanonaphthalene] K 1148
4,5-epoxy-4,11,11-trimethyl-8- 1139-30-6 DEFHJK
methylenebicyclo(7.2.0)undecane 1149
1,3,4,6,7,8alpha-hexahydro-1,1,5,5- 23787-90-8 DEFHIJK
tetramethyl-2H-2,4alpha- methanophtalen-8(5H)-one
TABLE-US-00006 TABLE 5 List of materials with ALL MORVs greater
than 5 to 10 Num- CAS Comment ber Material Name Number Code 248
Hydroxymethyl isolongifolene 59056-64-3 BDEFHJK
TABLE-US-00007 TABLE 6 List of materials with ALL MORVs from 0.5 to
less than 1 Num- CAS Comment ber Material Name Number Code 472
Decyl anthranilate 18189-07-6 DEFHJ 526 (Z)-3-methyl-2-(pent-2-en-
488-10-8 BCHIJKL 1-yl)cyclopent-2-en-1-one
[0016] The materials in Tables 1-6 can be supplied by one or more
of the following: Firmenich Inc. of Plainsboro N.J. USA;
International Flavor and Fragrance Inc. New York, N.Y. USA;
Takasago Corp. Teterboro, N.J. USA; Symrise Inc. Teterboro, N.J.
USA; Sigma-Aldrich/SAFC Inc. Carlsbad, Calif. USA; and Bedoukian
Research Inc. Danbury, Conn. USA.
[0017] Actual MORV values for each material listed in Tables 1-6
above are as follows:
TABLE-US-00008 MORV MORV MORV MORV Material value for Value for
Value for value for No. Equation a.) Equation b.) Equation c.)
Equation d.) 1 0.548223914 0.876283261 1.22018588 -0.41901144 2
1.520311929 3.493450446 2.70657265 5.11342862 3 2.267801995
-0.81712657 0.43218875 1.595983683 4 -0.591063369 -0.48283571
0.16199804 1.210497701 7 1.437444636 2.131822996 3.81633465
1.318339345 9 2.151445882 -0.46189495 0.56090469 1.206360803 10
2.5733592 -0.58780849 1.39751471 1.258361951 11 3.052627325
1.008519135 -0.30475953 0.076323462 12 0.683776599 -0.01157903
0.82853231 0.326169402 13 1.549643217 1.809183231 0.70864531
2.22799611 14 2.82111224 2.339505033 1.240818 2.502429355 16
-0.31551128 -0.06816599 -0.04371934 2.76742389 17 -1.334904153
-0.5773313 1.75644798 1.898455724 18 -1.34154226 -2.63596666
0.06885109 1.001431671 19 0.15532384 0.09866097 0.64214585
-0.33330779 20 0.640261783 0.693213268 0.54637273 -0.97556029 21
0.936895364 -0.01521118 1.1697513 -0.63510809 22 1.158981042
1.115900089 -0.25859776 1.318200884 23 3.702361074 1.399942641
5.23954766 7.089933671 24 0.773874141 0.146848137 -1.05705847
-0.36193173 25 -1.016103969 -1.18967936 0.78064625 2.944710012 25
-1.016103969 -1.18967936 0.78064625 2.944710012 26 0.615085491
-0.00096877 -0.35697252 -0.18121401 27 0.70261974 -0.22197386
0.19710806 -2.37196477 28 1.366472597 -0.42546942 -0.59394241
-0.01417395 29 1.096043453 -1.02972898 -1.42167356 -0.63817943 30
1.143415203 -0.85945441 -0.41416913 2.499807942 31 1.138642907
-0.19595476 -0.54547769 -0.98828898 32 1.914414495 -0.64487788
0.63212987 1.166699371 33 0.314847366 1.848003955 -1.3905032
-0.62848261 34 -0.113542761 0.981530917 0.32824239 1.126524277 35
0.472382903 1.494882467 -0.07201236 -0.64589543 36 3.158513795
1.084094934 -0.00328981 -0.17786385 37 -1.055631982 2.240172964
0.92596118 2.105391988 38 3.158513795 0.592820874 -0.49326241
0.212867212 39 1.083800659 2.069727985 2.48170879 3.205630609 42
-0.103134861 0.267726008 -0.65350189 1.125952363 43 0.323961628
1.469295081 -0.52991193 0.797908251 47 1.703678841 1.348737095
2.00634162 -0.16505407 48 2.370955056 2.783472865 2.68240273
1.221864405 49 1.670680003 -0.41866107 -0.9173849 1.181929544 50
1.670680003 0.076369374 -0.49915943 -0.85392575 52 0.464485039
0.057512869 1.31230219 -0.11170276 53 0.626671823 -0.46954947
-0.33383736 0.277079201 54 0.666149043 0.009549925 -0.36226343
0.197224432 55 0.723473579 -1.50916383 -0.3848989 -0.71458778 57
0.381273227 1.192994109 1.65593321 -1.65739236 59 0.561360663
-0.17793966 -1.63250554 -0.7564969 61 0.146473611 -0.01535544
-0.16339658 1.738656146 62 1.20162032 -0.3576095 -0.10695443
1.322155191 63 1.084291915 2.258720158 -1.01245416 1.688283974 64
0.744770665 0.155243763 -1.8029919 1.023503542 65 0.972835178
2.797151284 1.53453579 0.857051645 67 2.069410561 0.021831924
0.37855159 -0.67235457 68 0.527636614 0.590831983 1.02843762
2.208655795 69 2.133965691 2.088998449 2.05751412 -0.9433713 70
0.327378959 0.996844599 1.23648533 -1.25138371 71 1.40093669
0.778222691 0.70401172 -0.24075444 72 0.617697349 -0.29503359
0.52404847 0.816184656 73 0.617792473 0.888976061 -0.45289639
0.615659244 74 1.437359024 1.548292147 0.10314807 -0.48982286 75
-1.970885622 3.398008325 4.08025266 -0.89948156 76 -1.32746934
-2.65365233 0.10272816 1.001614125 77 -2.541686116 3.295534192
3.75284227 0.404837808 78 -2.110794 2.109874746 3.13350902
-0.3880285 79 1.641162056 -0.28533994 1.53676145 0.652696023 80
1.594400214 0.283682865 2.23140233 1.111682021 81 0.176566806
-2.0786518 -2.13986952 0.981126964 82 0.980373758 -0.28813159
0.19404501 1.252564677 83 0.941833098 0.317310013 1.17606727
0.72992237 84 0.774237336 -0.27140727 0.72461427 -1.56415746 85
2.092976965 0.810644229 0.82999192 -0.62861806 91 2.061595915
-0.79930338 -0.18285395 -0.66898499 92 2.068748434 -0.24299896
0.07214682 -1.11758276 93 -0.08984279 -1.06025959 -0.05068694
1.560050105 96 0.927758203 -0.44129515 0.89190422 0.744284978 97
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4.53384262 2.625871865
Delivery Systems and Methods
[0018] Non-limiting examples of suitable delivery systems, methods
of making delivery systems and the uses of such delivery systems
are disclosed in USPA 2007/0275866 A1. Such delivery systems
include:
Polymer Assisted Delivery (PAD):
[0019] This delivery technology uses polymeric materials to deliver
materials. Classical coacervation, water soluble or partly soluble
to insoluble charged or neutral polymers, liquid crystals, hot
melts, hydrogels, perfumed plastics, microcapsules, nano- and
micro-latexes, polymeric film formers, and polymeric absorbents,
polymeric adsorbents, etc. are some examples. PAD includes but is
not limited to: [0020] Matrix Systems: The fragrance is dissolved
or dispersed in a polymer matrix or particle. Perfumes, for
example, may be 1) dispersed into the polymer prior to formulating
into the product or 2) added separately from the polymer during or
after formulation of the product. Diffusion of perfume from the
polymer is a common trigger that allows or increases the rate of
perfume release from a polymeric matrix system that is deposited or
applied to the desired surface (situs), although many other
triggers are known that may control perfume release. Absorption
and/or adsorption into or onto polymeric particles, films,
solutions, and the like are aspects of this technology. Nano- or
micro-particles composed of organic materials (e.g., latexes) are
examples. Suitable particles include a wide range of materials
including, but not limited to polyacetal, polyacrylate,
polyacrylic, polyacrylonitrile, polyamide, polyaryletherketone,
polybutadiene, polybutylene, polybutylene terephthalate,
polychloroprene, polyethylene, polyethylene terephthalate,
polycyclohexylene dimethylene terephthalate, polycarbonate,
polychloroprene, polyhydroxyalkanoate, polyketone, polyester,
polyetherimide, polyethersulfone, polyethylenechlorinates,
polyimide, polyisoprene, polylactic acid, polymethylpentene,
polyphenylene oxide, polyphenylene sulfide, polyphthalamide,
polypropylene, polystyrene, polysulfone, polyvinyl acetate,
polyvinyl chloride, as well as polymers or copolymers based on
acrylonitrile-butadiene, cellulose acetate, ethylene-vinyl acetate,
ethylene vinyl alcohol, styrene-butadiene, vinyl acetate-ethylene,
and mixtures thereof. [0021] "Standard" systems refer to those that
are "pre-loaded" with the intent of keeping the pre-loaded perfume
associated with the polymer until the moment or moments of perfume
release. Such polymers may also suppress the neat product odor and
provide a bloom and/or longevity benefit depending on the rate of
perfume release. One challenge with such systems is to achieve the
ideal balance between 1) in-product stability (keeping perfume
inside carrier until you need it) and 2) timely release (during use
or from dry situs). Achieving such stability is particularly
important during in-product storage and product aging. This
challenge is particularly apparent for aqueous-based,
surfactant-containing products, such as heavy duty liquid laundry
detergents. Many "Standard" matrix systems available effectively
become "Equilibrium" systems when formulated into aqueous-based
products. One may select an "Equilibrium" system or a Reservoir
system, which has acceptable in-product diffusion stability and
available triggers for release (e.g., friction). "Equilibrium"
systems are those in which the perfume and polymer may be added
separately to the product, and the equilibrium interaction between
perfume and polymer leads to a benefit at one or more consumer
touch points (versus a free perfume control that has no
polymer-assisted delivery technology). The polymer may also be
pre-loaded with perfume; however, part or all of the perfume may
diffuse during in-product storage reaching an equilibrium that
includes having desired perfume raw materials (PRMs) associated
with the polymer. The polymer then carries the perfume to the
surface, and releases it typically via perfume diffusion. The use
of such equilibrium system polymers has the potential to decrease
the odor intensity of the neat product (usually more so in the case
of pre-loaded standard systems). Deposition of such polymers may
serve to "flatten" the release profile and provide increased
longevity. As indicated above, such longevity would be achieved by
suppressing the initial intensity and may enable the formulator to
use more high impact or low odor detection threshold (ODT) or low
Kovats Index (KI) PRMs to achieve FMOT benefits without initial
intensity that is too strong or distorted. It is important that
perfume release occurs within the time frame of the application to
impact the desired consumer touch point or touch points. Matrix
systems also include hot melt adhesives and perfume plastics. In
addition, hydrophobically modified polysaccharides may be
formulated into the perfumed product to increase perfume deposition
and/or modify perfume release. All such matrix systems, including
for example polysaccarides and nanolatexes may be combined with
other PDTs, including other PAD systems such as PAD reservoir
systems in the form of a perfume microcapsule (PMC). [0022]
Silicones are also examples of polymers that may be used as PDT,
and can provide perfume benefits in a manner similar to the
polymer-assisted delivery "matrix system". Such a PDT is referred
to as silicone-assisted delivery (SAD). One may pre-load silicones
with perfume, or use them as an equilibrium system as described for
PAD. Examples of silicones include polydimethylsiloxane and
polyalkyldimethylsiloxanes. Other examples include those with amine
functionality, which may be used to provide benefits associated
with amine-assisted delivery (AAD) and/or polymer-assisted delivery
(PAD) and/or amine-reaction products (ARP).
Reservoir Systems:
[0023] Reservoir systems are also known as a core-shell type
technology, or one in which the material that will be delivered is
surrounded by a release controlling membrane, which may serve as a
protective shell. The material inside the microcapsule is referred
to as the core, internal phase, or fill, whereas the wall is
sometimes called a shell, coating, or membrane. Microparticles or
pressure sensitive capsules or microcapsules are examples of this
technology. Microcapsules of the current invention are formed by a
variety of procedures that include, but are not limited to,
coating, extrusion, spray-drying, interfacial, in-situ and matrix
polymerization. The possible shell materials vary widely in their
stability toward water. Among the most stable are
polyoxymethyleneurea (PMU)-based materials, which may hold certain
PRMs for even long periods of time in aqueous solution (or
product). Such systems include but are not limited to
urea-formaldehyde and/or melamine-formaldehyde. Gelatin-based
microcapsules may be prepared so that they dissolve quickly or
slowly in water, depending for example on the degree of
cross-linking. Many other capsule wall materials are available and
vary in the degree of perfume diffusion stability observed. Without
wishing to be bound by theory, the rate of release of perfume from
a capsule, for example, once deposited on a surface is typically in
reverse order of in-product perfume diffusion stability. As such,
urea-formaldehyde and melamine-formaldehyde microcapsules for
example, typically require a release mechanism other than, or in
addition to, diffusion for release, such as mechanical force (e.g.,
friction, pressure, shear stress) that serves to break the capsule
and increase the rate of perfume (fragrance) release. Other
triggers include melting, dissolution, hydrolysis or other chemical
reaction, electromagnetic radiation, and the like. The use of
pre-loaded microcapsules requires the proper ratio of in-product
stability and in-use and/or on-surface (on-situs) release, as well
as proper selection of PRMs. Microcapsules that are based on
urea-formaldehyde and/or melamine-formaldehyde are relatively
stable, especially in near neutral aqueous-based solutions. These
materials may require a friction trigger which may not be
applicable to all product applications. Other microcapsule
materials (e.g., gelatin) may be unstable in aqueous-based products
and may even provide reduced benefit (versus free perfume control)
when in-product aged. Scratch and sniff technologies are yet
another example of PAD.
Molecule-Assisted Delivery (MAD):
[0024] Non-polymer materials or molecules may also serve to improve
the delivery of materials. Without wishing to be bound by theory,
perfume may non-covalently interact with organic materials,
resulting in altered deposition and/or release. Non-limiting
examples of such organic materials include but are not limited to
hydrophobic materials such as organic oils, waxes, mineral oils,
petrolatum, fatty acids or esters, sugars, surfactants, liposomes
and even other perfume raw material (perfume oils), as well as
natural oils, including body and/or other soils. Perfume fixatives
are yet another example. In one aspect, non-polymeric materials or
molecules have a Log P greater than about 2.
Cyclodextrin (CD):
[0025] This technology approach uses a cyclic oligosaccharide or
cyclodextrin to improve the delivery of materials. Typically a
perfume and cyclodextrin (CD) complex is formed. Such complexes may
be preformed, formed in-situ, or formed on or in the situs. Without
wishing to be bound by theory, loss of water may serve to shift the
equilibrium toward the CD-Perfume complex, especially if other
adjunct ingredients (e.g., surfactant) are not present at high
concentration to compete with the perfume for the cyclodextrin
cavity. A bloom benefit may be achieved if water exposure or an
increase in moisture content occurs at a later time point. In
addition, cyclodextrin allows the perfume formulator increased
flexibility in selection of PRMs. Cyclodextrin may be pre-loaded
with perfume or added separately from perfume to obtain the desired
perfume stability, deposition or release benefit.
Starch Encapsulated Accord (SEA):
[0026] The use of a starch encapsulated accord (SEA) technology
allows one to modify the properties of the material that will be
delivered, for example, by converting a liquid perfume into a solid
by adding ingredients such as starch. The benefit includes
increased perfume retention during product storage, especially
under non-aqueous conditions. Upon exposure to moisture, a perfume
bloom may be triggered. Benefits at other moments of truth may also
be achieved because the starch allows the product formulator to
select PRMs or PRM concentrations that normally cannot be used
without the presence of SEA. Another technology example includes
the use of other organic and inorganic materials, such as silica to
convert perfume from liquid to solid.
Zeolite & Inorganic Carrier (ZIC):
[0027] This technology relates to the use of porous zeolites or
other inorganic materials to deliver materials. By way of example,
perfume-loaded zeolite may be used with or without adjunct
ingredients used for example to coat the perfume-loaded zeolite
(PLZ) to change its perfume release properties during product
storage or during use or from the dry situs. Silica is another form
of ZIC. Another example of a suitable inorganic carrier includes
inorganic tubules, where the perfume or other active material is
contained within the lumen of the nano- or micro-tubules.
Preferably, the perfume-loaded inorganic tubule (or Perfume-Loaded
Tubule or PLT) is a mineral nano- or micro-tubule, such as
halloysite or mixtures of halloysite with other inorganic
materials, including other clays. The PLT technology may also
comprise additional ingredients on the inside and/or outside of the
tubule for the purpose of improving in-product diffusion stability,
deposition on the desired situs or for controlling the release rate
of the loaded perfume. Monomeric and/or polymeric materials,
including starch encapsulation, may be used to coat, plug, cap, or
otherwise encapsulate the PLT.
[0028] A delivery system comprising, based on total delivery system
weight, a sum total of from about 0.00025% to about 30%, preferably
from about 0.0025% to about 10%, more preferably from about 0.005%
to about 5%, most preferably from about 0.01% to about 4% of a
benefit agent that comprises one or more malodor reduction
materials, preferably 1 to about 20 malodor reduction materials,
more preferably 1 to about 15 malodor reduction materials, most
preferably 1 to about 10 malodor reduction materials, each of said
malodor reduction materials having a MORV of at least 0.5,
preferably from 0.5 to 10, more preferably from 1 to 10, most
preferably from 1 to 5, and preferably each of said malodor
reduction materials having a Universal MORV, said sum total of
malodor reduction materials having a Blocker Index of less than 3,
more preferable less than about 2.5 even more preferably less than
about 2 and still more preferably less than about 1 and most
preferably 0 and/or a Blocker Index average of 3 to about 0.001;
and optionally an additional benefit agent, is disclosed.
[0029] In one aspect of said delivery system each of said malodor
reduction materials may have an MORV of 1 or greater, 2 or greater,
3 or greater, 4 or greater, 5 or greater, 6 or greater, 7 or
greater, 8 or greater, 9 or greater, preferably for each of such
ranges, the upper limit is about 10. In one aspect of said delivery
system, said malodor reduction materials have a Fragrance Fidelity
Index of less than 3, preferably less than 2, more preferably less
than 1 and most preferably 0 and/or a Fragrance Fidelity Index
average of 3 to about 0.001 Fragrance Fidelity Index.
[0030] In one aspect of said delivery system, said one or more
malodor reduction materials is selected from the group consisting
of about 0.01 to about 80% malodor reduction composition,
preferably from about 0.1 to 70% malodor reduction composition,
more preferably from about 0.5 to 60% malodor reduction
composition, most preferably from about 1.0 to 40% malodor
reduction composition.
[0031] In one aspect of said delivery system, said delivery system
is selected from the group consisting of:
[0032] a) a Polymer Assisted Delivery (PAD) system comprising,
based on total benefit agent weight, from about 0.1 to about 50%
Malodor reducing composition
[0033] b) a Molecule-Assisted Delivery (MAD) system, comprising,
based on total benefit agent weight, from about 0.1 to about 75%
Malodor reducing composition.
[0034] c) a Cyclodextrin (CD) system comprising, based on total
benefit agent weight, from about 0.1 to about 20% Malodor reducing
composition.
[0035] d) a Starch Encapsulated Accord (SEA) system comprising,
based on total benefit agent weight, from about 0.1 to about 80%
Malodor reducing composition.
[0036] e) a Zeolite & Inorganic Carrier (ZIC) system
comprising, based on total benefit agent weight, from about 0.1 to
about 30% Malodor reducing composition.
[0037] In one aspect of said delivery system, said Polymer Assisted
Delivery (PAD) system comprises a Polymer Assisted Delivery (PAD)
Reservoir system.
[0038] In one aspect of said delivery system, said Polymer Assisted
Delivery (PAD) Reservoir system is a perfume delivery particle that
comprises a shell material and a core material, said shell material
encapsulating said core material, said core material comprising a
malodor reduction material according to claims 1 and said shell
comprising a material selected from the group consisting of
polyethylenes; polyamides; polystyrenes; polyisoprenes;
polycarbonates; polyesters; polyacrylates; aminoplasts, in one
aspect said aminoplast comprises a polyureas, polyurethane, and/or
polyureaurethane, in one aspect said polyurea comprises
polyoxymethyleneurea and/or melamine formaldehyde; polyvinylamine,
polyvinyl formamide, polyolefins; polyvinyl alcohol,
polysaccharides, in one aspect alginate and/or chitosan; gelatin;
shellac; epoxy resins; vinyl polymers; water insoluble inorganics;
silicone; and mixtures thereof, preferably said perfume delivery
particle have a volume weighted mean particle size from about, from
about 5 microns to about 45 microns more preferably from about 8
microns to about 25 microns, or alternatively a volume weighted
mean particle size from about, from about 25 microns to about 60
microns, more preferably from about 25 microns to about 60
microns.
[0039] In one aspect of said delivery system, said shell comprises
melamine formaldehyde and/or cross linked melamine
formaldehyde.
[0040] In one aspect of said delivery system, said shell is coated
by a water-soluble cationic polymer selected from the group that
consists of polysaccharides, cationically modified starch and
cationically modified guar, polysiloxanes, dimethyldiallylammonium
polyhalogenides, copolymers of dimethyldiallylammonium polychloride
and vinyl pyrrolidone, acrylamides, imidazoles, imidazolinium
halogenides and imidazolium halogenides and polyvinyl amine and its
copolymers with N-vinyl formamide.
[0041] In one aspect of said delivery system, said coating that
coats said shell, comprises a cationic polymer and an anionic
polymer.
[0042] In one aspect of said delivery system, said cationic polymer
comprises hydroxyl ethyl cellulose; and said anionic polymer
comprises carboxyl methyl cellulose.
[0043] In one aspect of said delivery system, said reduction
materials are selected from the group consisting of Table 1
materials and mixtures thereof; preferably said material is
selected from the group consisting of Table 1 materials 1, 2, 3, 4,
7, 9, 10, 11, 13, 14, 16, 17, 18, 21, 22, 23, 25, 28, 29, 30, 31,
32, 33, 34, 35, 36, 37, 38, 39, 42, 43, 47, 48, 49, 50, 52, 57, 61,
62, 63, 64, 65, 67, 68, 69, 70, 71, 74, 75, 76, 77, 78, 79, 80, 82,
83, 85, 91, 92, 93, 98, 100, 101, 102, 103, 104, 105, 106, 108,
109, 110, 112, 113, 114, 117, 119, 120, 122, 123, 126, 128, 130,
134, 135, 137, 140, 141, 142, 143, 145, 146, 148, 149, 152, 153,
155, 156, 158, 159, 161, 162, 167, 168, 170, 174, 175, 176, 177,
178, 179, 182, 183, 184, 185, 186, 187, 189, 190, 192, 193, 195,
196, 197, 199, 206, 208, 209, 210, 211, 212, 215, 218, 221, 227,
228, 229, 230, 231, 233, 234, 238, 242, 243, 244, 246, 247, 249,
252, 253, 254, 256, 259, 260, 261, 263, 267, 269, 271, 274, 276,
277, 278, 280, 281, 285, 286, 288, 289, 290, 292, 293, 294, 295,
296, 300, 301, 303, 307, 316, 317, 318, 321, 322, 323, 324, 325,
328, 329, 330, 331, 332, 333, 334, 335, 336, 338, 339, 342, 343,
344, 347, 349, 350, 352, 353, 356, 358, 359, 360, 361, 362, 363,
364, 368, 369, 370, 371, 372, 373, 374, 375, 377, 378, 381, 385,
386, 388, 390, 391, 394, 397, 398, 407, 413, 414, 415, 416, 417,
418, 421, 424, 425, 426, 428, 429, 432, 436, 441, 444, 445, 449,
450, 453, 457, 459, 461, 462, 463, 464, 465, 466, 467, 468, 470,
471, 473, 474, 475, 478, 479, 480, 482, 484, 485, 486, 487, 488,
491, 493, 497, 498, 501, 502, 503, 505, 519, 520, 521, 524, 527,
529, 530, 531, 532, 534, 537, 541, 544, 546, 548, 550, 551, 552,
553, 555, 558, 559, 560, 561, 562, 563, 565, 566, 567, 568, 569,
570, 571, 572, 573, 574, 577, 578, 580, 581, 582, 584, 586, 587,
589, 591, 592, 594, 595, 599, 600, 601, 603, 604, 606, 607, 608,
609, 610, 611, 612, 613, 614, 615, 616, 618, 620, 621, 624, 625,
626, 627, 628, 631, 632, 633, 635, 636, 638, 639, 644, 649, 650,
653, 655, 658, 659, 660, 661, 663, 668, 671, 673, 674, 675, 676,
677, 678, 679, 680, 681, 682, 683, 684, 686, 691, 692, 693, 694,
696, 697, 698, 700, 702, 704, 706, 707, 708, 709, 710, 711, 712,
713, 714, 715, 716, 717, 718, 719, 720, 721, 722, 723, 724, 725,
726, 727, 730, 731, 733, 735, 736, 738, 741, 742, 746, 748, 750,
752, 754, 757, 758, 763, 764, 766, 767, 768, 769, 770, 771, 772,
774, 775, 776, 778, 781, 782, 786, 788, 791, 792, 800, 802, 803,
804, 805, 806, 807, 814, 821, 824, 826, 827, 828, 829, 831, 833,
834, 837, 839, 840, 849, 850, 852, 856, 864, 865, 866, 868, 869,
870, 871, 872, 873, 876, 877, 878, 879, 881, 884, 885, 886, 890,
892, 893, 894, 897, 905, 908, 912, 913, 914, 916, 919, 920, 922,
923, 924, 925, 926, 927, 928, 929, 930, 933, 937, 939, 941, 942,
943, 945, 946, 947, 948, 950, 951, 953, 954, 955, 959, 962, 965,
967, 969, 973, 974, 976, 978, 980, 982, 985, 988, 993, 998, 1000,
1003, 1006, 1007, 1008, 1009, 1010, 1012, 1016, 1020, 1021, 1022,
1023, 1024, 1025, 1026, 1027, 1028, 1029, 1031, 1032, 1033, 1035,
1036, 1037, 1038, 1042, 1043, 1045, 1046, 1047, 1053, 1057, 1059,
1060, 1062, 1063, 1064, 1065, 1066, 1067, 1070, 1072, 1073, 1075,
1077, 1078, 1082, 1083, 1085, 1089, 1090, 1091, 1093, 1095, 1097,
1099, 1102, 1104, 1105, 1107, 1111, 1113, 1116, 1117, 1120, 1121,
1125, 1126, 1129, 1131, 1135, 1136, 1137, 1138, 1139, 1140, 1142,
1143, 1144, 1145, 1146, 1147, 1148, 1149, Table 2 materials 2, 23,
141, 185, 227, 230, 246, 248, 343, 359, 565, 631, 659, 674, 678,
679, 715, 758, 1028, 1097, Table 3 materials 12, 19, 20, 24, 26,
27, 53, 54, 55, 59, 72, 73, 81, 84, 96, 97, 107, 111, 115, 116,
125, 133, 147, 150, 151, 154, 157, 163, 166, 169, 181, 191, 194,
198, 201, 204, 205, 213, 214, 232, 237, 239, 255, 258, 264, 270,
273, 275, 282, 283, 284, 287, 302, 306, 308, 310, 312, 314, 319,
346, 354, 355, 365, 366, 376, 379, 387, 400, 412, 419, 420, 437,
438, 439, 440, 442, 443, 447, 448, 454, 455, 469, 472, 477, 481,
492, 495, 496, 504, 509, 510, 512, 515, 517, 518, 522, 525, 526,
528, 535, 536, 538, 540, 542, 547, 549, 554, 556, 557, 575, 576,
579, 583, 585, 588, 602, 605, 617, 619, 640, 641, 645, 647, 651,
652, 662, 664, 665, 667, 672, 687, 699, 701, 703, 740, 743, 744,
745, 755, 760, 761, 777, 779, 784, 789, 796, 797, 799, 808, 810,
811, 812, 817, 819, 820, 832, 835, 836, 838, 845, 846, 847, 848,
851, 858, 875, 880, 882, 883, 888, 889, 891, 899, 900, 901, 902,
903, 904, 909, 918, 921, 931, 940, 956, 958, 960, 971, 977, 981,
983, 986, 987, 994, 995, 1001, 1002, 1004, 1005, 1011, 1017, 1018,
1019, 1030, 1039, 1040, 1041, 1051, 1052, 1054, 1055, 1058, 1061,
1069, 1071, 1074, 1076, 1079, 1081, 1084, 1088, 1098, 1110, 1112,
1115, 1118, 1119, 1122, 1127, 1128, 1133, 1134, 1141 and mixtures
thereof; preferably said malodor reduction materials are selected
from the group consisting of Table 1 materials 1, 2, 3, 4, 7, 9,
10, 11, 13, 14, 16, 17, 18, 21, 22, 23, 25, 28, 29, 30, 31, 32, 33,
34, 35, 36, 37, 38, 39, 42, 43, 47, 48, 49, 50, 52, 57, 61, 62, 63,
64, 65, 67, 68, 69, 70, 71, 74, 75, 76, 77, 78, 79, 80, 82, 83, 85,
91, 92, 93, 98, 100, 101, 102, 103, 104, 105, 106, 108, 109, 110,
112, 113, 114, 117, 119, 120, 122, 123, 126, 128, 130, 134, 135,
137, 140, 141, 142, 143, 145, 146, 148, 149, 152, 153, 155, 156,
158, 159, 161, 162, 167, 168, 170, 174, 175, 176, 177, 178, 179,
182, 183, 184, 185, 186, 187, 189, 190, 192, 193, 195, 196, 197,
199, 206, 208, 209, 210, 211, 212, 215, 218, 221, 227, 228, 229,
230, 231, 233, 234, 238, 242, 243, 244, 246, 247, 249, 252, 253,
254, 256, 259, 260, 261, 263, 267, 269, 271, 274, 276, 277, 278,
280, 281, 285, 286, 288, 289, 290, 292, 293, 294, 295, 296, 300,
301, 303, 307, 316, 317, 318, 321, 322, 323, 324, 325, 328, 329,
330, 331, 332, 333, 334, 335, 336, 338, 339, 342, 343, 344, 347,
349, 350, 352, 353, 356, 358, 359, 360, 361, 362, 363, 364, 368,
369, 370, 371, 372, 373, 374, 375, 377, 378, 381, 385, 386, 388,
390, 391, 394, 397, 398, 407, 413, 414, 415, 416, 417, 418, 421,
424, 425, 426, 428, 429, 432, 436, 441, 444, 445, 449, 450, 453,
457, 459, 461, 462, 463, 464, 465, 466, 467, 468, 470, 471, 473,
474, 475, 478, 479, 480, 482, 484, 485, 486, 487, 488, 491, 493,
497, 498, 501, 502, 503, 505, 519, 520, 521, 524, 527, 529, 530,
531, 532, 534, 537, 541, 544, 546, 548, 550, 551, 552, 553, 555,
558, 559, 560, 561, 562, 563, 565, 566, 567, 568, 569, 570, 571,
572, 573, 574, 577, 578, 580, 581, 582, 584, 586, 587, 589, 591,
592, 594, 595, 599, 600, 601, 603, 604, 606, 607, 608, 609, 610,
611, 612, 613, 614, 615, 616, 618, 620, 621, 624, 625, 626, 627,
628, 631, 632, 633, 635, 636, 638, 639, 644, 649, 650, 653, 655,
658, 659, 660, 661, 663, 668, 671, 673, 674, 675, 676, 677, 678,
679, 680, 681, 682, 683, 684, 686, 691, 692, 693, 694, 696, 697,
698, 700, 702, 704, 706, 707, 708, 709, 710, 711, 712, 713, 714,
715, 716, 717, 718, 719, 720, 721, 722, 723, 724, 725, 726, 727,
730, 731, 733, 735, 736, 738, 741, 742, 746, 748, 750, 752, 754,
757, 758, 763, 764, 766, 767, 768, 769, 770, 771, 772, 774, 775,
776, 778, 781, 782, 786, 788, 791, 792, 800, 802, 803, 804, 805,
806, 807, 814, 821, 824, 826, 827, 828, 829, 831, 833, 834, 837,
839, 840, 849, 850, 852, 856, 864, 865, 866, 868, 869, 870, 871,
872, 873, 876, 877, 878, 879, 881, 884, 885, 886, 890, 892, 893,
894, 897, 905, 908, 912, 913, 914, 916, 919, 920, 922, 923, 924,
925, 926, 927, 928, 929, 930, 933, 937, 939, 941, 942, 943, 945,
946, 947, 948, 950, 951, 953, 954, 955, 959, 962, 965, 967, 969,
973, 974, 976, 978, 980, 982, 985, 988, 993, 998, 1000, 1003, 1006,
1007, 1008, 1009, 1010, 1012, 1016, 1020, 1021, 1022, 1023, 1024,
1025, 1026, 1027, 1028, 1029, 1031, 1032, 1033, 1035, 1036, 1037,
1038, 1042, 1043, 1045, 1046, 1047, 1053, 1057, 1059, 1060, 1062,
1063, 1064, 1065, 1066, 1067, 1070, 1072, 1073, 1075, 1077, 1078,
1082, 1083, 1085, 1089, 1090, 1091, 1093, 1095, 1097, 1099, 1102,
1104, 1105, 1107, 1111, 1113, 1116, 1117, 1120, 1121, 1125, 1126,
1129, 1131, 1135, 1136, 1137, 1138, 1139, 1140, 1142, 1143, 1144,
1145, 1146, 1147, 1148, 1149, Table 2 materials 2, 23, 141, 185,
227, 230, 246, 248, 343, 359, 565, 631, 659, 674, 678, 679, 715,
758, 1028, 1097 and mixtures thereof, more preferably said malodor
reduction materials are selected from the group consisting of Table
4 materials 7, 14, 39, 48, 183, 199, 206, 212, 215, 229, 260, 261,
281, 329, 335, 353, 360, 441, 484, 487, 488, 501, 566, 567, 569,
570, 573, 574, 603, 616, 621, 624, 627, 632, 663, 680, 684, 694,
696, 708, 712, 714, 726, 750, 764, 775, 776, 788, 804, 872, 919,
927, 933, 978, 1007, 1022, 1024, 1027, 1029, 1035, 1038, 1060,
1089, 1107, 1129, 1131, 1136, 1137, 1140, 1142, 1143, 1144, 1145,
1148, 1149, Table 5 material 248 and mixtures thereof, most
preferably said malodor reduction materials are selected from the
group consisting of Table 4 materials 261, 680, 788, 1129, 1148,
1149 and mixtures thereof.
[0044] In one aspect of said delivery system, said delivery system
is a perfume delivery particle that comprises a shell material and
a core material, said shell material encapsulating said core
material, said core material comprising a malodor reduction
material selected from the group consisting of Table 1 materials 1,
2, 3, 4, 7, 9, 10, 11, 13, 14, 16, 18, 21, 22, 23, 25, 28, 29, 30,
32, 34, 35, 36, 37, 38, 39, 42, 43, 47, 48, 49, 52, 57, 63, 65, 67,
68, 69, 70, 71, 74, 75, 76, 77, 78, 79, 80, 83, 85, 92, 93, 100,
101, 102, 103, 104, 105, 106, 109, 112, 113, 114, 123, 126, 128,
130, 134, 135, 137, 140, 141, 142, 143, 145, 148, 149, 152, 153,
155, 156, 158, 159, 161, 162, 167, 168, 170, 174, 175, 176, 177,
178, 179, 182, 183, 184, 185, 186, 189, 192, 193, 195, 196, 197,
199, 206, 208, 209, 210, 211, 212, 215, 218, 221, 227, 228, 229,
230, 231, 233, 234, 238, 242, 244, 246, 247, 249, 252, 253, 256,
260, 261, 263, 267, 269, 271, 274, 276, 277, 278, 280, 281, 285,
286, 288, 289, 290, 292, 293, 294, 295, 296, 300, 301, 303, 307,
316, 317, 318, 322, 324, 325, 328, 329, 330, 331, 332, 333, 334,
335, 336, 338, 339, 342, 343, 344, 347, 349, 350, 352, 353, 356,
358, 359, 360, 361, 362, 363, 364, 368, 369, 370, 371, 372, 373,
374, 377, 378, 381, 385, 386, 388, 390, 391, 397, 398, 407, 413,
414, 415, 416, 417, 418, 421, 424, 426, 432, 436, 441, 444, 445,
449, 450, 457, 459, 461, 462, 463, 464, 465, 466, 467, 468, 470,
471, 473, 475, 478, 479, 480, 482, 484, 485, 486, 487, 488, 491,
497, 498, 501, 502, 503, 505, 519, 520, 521, 527, 529, 531, 534,
537, 541, 544, 548, 550, 552, 558, 559, 560, 561, 562, 563, 565,
566, 567, 568, 569, 570, 571, 572, 573, 574, 577, 582, 586, 587,
589, 591, 592, 594, 595, 599, 600, 601, 603, 604, 606, 607, 608,
609, 610, 611, 612, 613, 614, 615, 616, 618, 620, 621, 624, 625,
626, 627, 628, 631, 632, 633, 635, 636, 638, 639, 644, 650, 653,
658, 659, 660, 661, 663, 671, 673, 674, 675, 676, 677, 678, 679,
680, 681, 683, 684, 686, 691, 692, 693, 694, 696, 697, 698, 700,
702, 704, 706, 707, 708, 709, 710, 711, 712, 713, 714, 715, 716,
717, 718, 719, 720, 721, 722, 723, 724, 725, 726, 727, 731, 741,
742, 746, 748, 750, 752, 754, 757, 758, 763, 766, 768, 769, 771,
774, 775, 776, 778, 781, 782, 786, 788, 791, 800, 802, 803, 804,
806, 807, 814, 821, 826, 827, 828, 831, 833, 849, 850, 852, 866,
868, 870, 871, 872, 873, 876, 877, 878, 879, 881, 884, 885, 886,
890, 892, 893, 894, 897, 905, 908, 912, 913, 914, 916, 919, 920,
922, 923, 924, 925, 926, 927, 930, 933, 937, 939, 941, 942, 943,
945, 946, 947, 948, 950, 951, 953, 954, 959, 962, 965, 967, 973,
974, 976, 978, 980, 982, 985, 988, 998, 1000, 1003, 1006, 1007,
1008, 1009, 1010, 1012, 1016, 1020, 1022, 1023, 1024, 1025, 1026,
1027, 1028, 1029, 1031, 1032, 1033, 1035, 1036, 1037, 1038, 1043,
1045, 1046, 1047, 1053, 1057, 1059, 1060, 1062, 1063, 1065, 1075,
1083, 1085, 1089, 1090, 1091, 1093, 1095, 1097, 1099, 1102, 1104,
1105, 1107, 1111, 1116, 1117, 1120, 1121, 1125, 1126, 1129, 1131,
1135, 1136, 1137, 1139, 1140, 1142, 1143, 1144, 1145, 1146, 1147,
1148, 1149; Table 2 materials 2, 23, 141, 185, 227, 230, 246, 248,
343, 359, 565, 631, 659, 674, 678, 679, 715, 758, 1028, 1097; Table
3 materials 1, 9, 12, 13, 19, 20, 21, 24, 25, 27, 32, 34, 37, 38,
43, 53, 54, 55, 59, 65, 68, 70, 71, 72, 73, 79, 81, 83, 85, 96,
100, 105, 106, 109, 111, 114, 125, 126, 133, 134, 135, 137, 140,
142, 143, 147, 148, 150, 151, 152, 153, 154, 157, 159, 162, 167,
169, 178, 181, 189, 191, 192, 195, 197, 198, 201, 204, 211, 213,
228, 231, 232, 233, 234, 237, 238, 239, 242, 246, 252, 256, 270,
273, 275, 277, 285, 286, 288, 289, 290, 292, 293, 295, 300, 301,
306, 308, 310, 314, 319, 322, 325, 331, 333, 334, 336, 338, 339,
344, 354, 355, 356, 358, 361, 362, 363, 366, 370, 371, 372, 374,
376, 377, 378, 379, 381, 385, 387, 388, 390, 407, 412, 413, 417,
418, 419, 420, 432, 437, 438, 439, 440, 443, 444, 447, 448, 454,
455, 457, 461, 465, 467, 472, 477, 478, 479, 480, 481, 482, 485,
491, 496, 497, 502, 503, 504, 510, 512, 515, 517, 518, 525, 526,
529, 535, 536, 537, 540, 541, 544, 550, 557, 558, 559, 560, 561,
568, 571, 572, 575, 576, 585, 588, 589, 592, 594, 599, 600, 602,
604, 605, 609, 617, 619, 620, 625, 626, 633, 636, 638, 641, 644,
645, 647, 650, 651, 653, 662, 672, 673, 675, 676, 681, 683, 686,
687, 693, 697, 698, 700, 703, 704, 706, 707, 716, 717, 718, 722,
725, 740, 742, 745, 746, 755, 757, 769, 771, 779, 782, 799, 803,
806, 807, 819, 820, 827, 828, 833, 835, 838, 846, 847, 848, 850,
875, 878, 879, 880, 881, 883, 888, 889, 890, 891, 893, 899, 900,
901, 902, 903, 909, 912, 914, 918, 920, 921, 922, 923, 930, 937,
939, 940, 941, 945, 946, 947, 948, 953, 954, 958, 959, 960, 965,
967, 971, 981, 986, 994, 995, 998, 1000, 1001, 1003, 1004, 1005,
1008, 1009, 1010, 1011, 1017, 1018, 1019, 1020, 1023, 1026, 1030,
1031, 1032, 1036, 1040, 1046, 1047, 1051, 1052, 1053, 1054, 1055,
1057, 1058, 1061, 1062, 1063, 1071, 1074, 1075, 1081, 1088, 1091,
1093, 1095, 1098, 1099, 1102, 1104, 1105, 1111, 1115, 1116, 1119,
1120, 1122, 1127, 1128, 1134, 1135, 1139, 1146, 1147 and mixtures
thereof, preferably said malodor reduction material is selected
from the group consisting of Table 1 materials 1, 2, 3, 4, 7, 9,
10, 11, 13, 14, 16, 18, 21, 22, 23, 25, 28, 29, 30, 32, 34, 35, 36,
37, 38, 39, 42, 43, 47, 48, 49, 52, 57, 63, 65, 67, 68, 69, 70, 71,
74, 75, 76, 77, 78, 79, 80, 83, 85, 92, 93, 100, 101, 102, 103,
104, 105, 106, 109, 112, 113, 114, 123, 126, 128, 130, 134, 135,
137, 140, 141, 142, 143, 145, 148, 149, 152, 153, 155, 156, 158,
159, 161, 162, 167, 168, 170, 174, 175, 176, 177, 178, 179, 182,
183, 184, 185, 186, 189, 192, 193, 195, 196, 197, 199, 206, 208,
209, 210, 211, 212, 215, 218, 221, 227, 228, 229, 230, 231, 233,
234, 238, 242, 244, 246, 247, 249, 252, 253, 256, 260, 261, 263,
267, 269, 271, 274, 276, 277, 278, 280, 281, 285, 286, 288, 289,
290, 292, 293, 294, 295, 296, 300, 301, 303, 307, 316, 317, 318,
322, 324, 325, 328, 329, 330, 331, 332, 333, 334, 335, 336, 338,
339, 342, 343, 344, 347, 349, 350, 352, 353, 356, 358, 359, 360,
361, 362, 363, 364, 368, 369, 370, 371, 372, 373, 374, 377, 378,
381, 385, 386, 388, 390, 391, 397, 398, 407, 413, 414, 415, 416,
417, 418, 421, 424, 426, 432, 436, 441, 444, 445, 449, 450, 457,
459, 461, 462, 463, 464, 465, 466, 467, 468, 470, 471, 473, 475,
478, 479, 480, 482, 484, 485, 486, 487, 488, 491, 497, 498, 501,
502, 503, 505, 519, 520, 521, 527, 529, 531, 534, 537, 541, 544,
548, 550, 552, 558, 559, 560, 561, 562, 563, 565, 566, 567, 568,
569, 570, 571, 572, 573, 574, 577, 582, 586, 587, 589, 591, 592,
594, 595, 599, 600, 601, 603, 604, 606, 607, 608, 609, 610, 611,
612, 613, 614, 615, 616, 618, 620, 621, 624, 625, 626, 627, 628,
631, 632, 633, 635, 636, 638, 639, 644, 650, 653, 658, 659, 660,
661, 663, 671, 673, 674, 675, 676, 677, 678, 679, 680, 681, 683,
684, 686, 691, 692, 693, 694, 696, 697, 698, 700, 702, 704, 706,
707, 708, 709, 710, 711, 712, 713, 714, 715, 716, 717, 718, 719,
720, 721, 722, 723, 724, 725, 726, 727, 731, 741, 742, 746, 748,
750, 752, 754, 757, 758, 763, 766, 768, 769, 771, 774, 775, 776,
778, 781, 782, 786, 788, 791, 800, 802, 803, 804, 806, 807, 814,
821, 826, 827, 828, 831, 833, 849, 850, 852, 866, 868, 870, 871,
872, 873, 876, 877, 878, 879, 881, 884, 885, 886, 890, 892, 893,
894, 897, 905, 908, 912, 913, 914, 916, 919, 920, 922, 923, 924,
925, 926, 927, 930, 933, 937, 939, 941, 942, 943, 945, 946, 947,
948, 950, 951, 953, 954, 959, 962, 965, 967, 973, 974, 976, 978,
980, 982, 985, 988, 998, 1000, 1003, 1006, 1007, 1008, 1009, 1010,
1012, 1016, 1020, 1022, 1023, 1024, 1025, 1026, 1027, 1028, 1029,
1031, 1032, 1033, 1035, 1036, 1037, 1038, 1043, 1045, 1046, 1047,
1053, 1057, 1059, 1060, 1062, 1063, 1065, 1075, 1083, 1085, 1089,
1090, 1091, 1093, 1095, 1097, 1099, 1102, 1104, 1105, 1107, 1111,
1116, 1117, 1120, 1121, 1125, 1126, 1129, 1131, 1135, 1136, 1137,
1139, 1140, 1142, 1143, 1144, 1145, 1146, 1147, 1148, 1149; Table 2
materials 2, 23, 141, 185, 227, 230, 246, 248, 343, 359, 565, 631,
659, 674, 678, 679, 715, 758, 1028, 1097, and mixtures thereof,
most preferably said malodor reduction materials are selected from
the group consisting of Table 4 materials 7, 14, 39, 48, 183, 199,
206, 212, 215, 229, 260, 261, 281, 329, 335, 353, 360, 441, 484,
487, 488, 501, 566, 567, 569, 570, 573, 574, 603, 616, 621, 624,
627, 632, 663, 680, 684, 694, 696, 708, 712, 714, 726, 750, 775,
776, 788, 804, 872, 919, 927, 933, 978, 1007, 1022, 1024, 1027,
1029, 1035, 1038, 1060, 1089, 1107, 1129, 1131, 1136, 1137, 1140,
1142, 1143, 1144, 1145, 1148, 1149, Table 5 material 248 and
mixtures thereof. These are materials that are stable in perfume
microcapsules and do not leak so they will deposit and be available
to counteract the malodor.
[0045] A delivery system according to any of claims 6 through 9,
wherein said core comprises one or more malodor reduction materials
having a vapor pressure of greater than 0.01 torr, preferably,
greater than 0.01 torr to 10 torr, preferably said one or more
malodor materials are selected from the group consisting of Table 1
materials 3; 4; 7; 9; 21; 25; 29; 30; 32; 34; 35; 42; 49; 65; 67;
70; 92; 93; 101; 102; 103; 114; 123; 126; 130; 142; 145; 149; 155;
159; 167; 168; 170; 178; 186; 189; 192; 193; 208; 209; 210; 218;
228; 229; 231; 256; 267; 274; 278; 280; 281; 290; 294; 317; 318;
322; 325; 333; 338; 342; 344; 358; 362; 364; 386; 397; 398; 415;
421; 424; 436; 441; 444; 445; 449; 461; 466; 468; 471; 473; 475;
491; 519; 520; 527; 531; 534; 544; 565; 586; 587; 589; 603; 604;
606; 609; 611; 612; 614; 615; 618; 621; 627; 628; 631; 632; 633;
639; 659; 683; 686; 692; 693; 696; 698; 702; 708; 711; 714; 715;
717; 720; 725; 742; 748; 750; 752; 763; 766; 768; 774; 778; 781;
786; 791; 800; 802; 806; 814; 821; 826; 827; 828; 850; 852; 866;
868; 871; 873; 876; 877; 878; 879; 884; 897; 905; 914; 926; 937;
946; 947; 950; 973; 974; 982; 1006; 1008; 1010; 1016; 1020; 1031;
1037; 1043; 1045; 1053; 1057; 1060; 1062; 1102; 1104; 1105; 1120;
1125; 1137; 1144; 1145, Table 2 materials 565: 631; 659; 715, Table
3 materials 9; 12; 19; 20; 21; 24; 25; 27; 32; 34; 53; 55; 59; 65;
70; 73; 81; 96; 111; 114; 125; 126; 133; 142; 147; 150; 154; 157;
159; 167; 169; 178; 189; 192; 198; 201; 204; 228; 231; 232; 237;
239; 256; 270; 273; 290; 306; 319; 322; 325; 333; 338; 344; 354;
358; 362; 366; 376; 387; 412; 419; 420; 437; 438; 439; 443; 444;
447; 448; 461; 477; 481; 491; 496; 512; 517; 518; 525; 535; 536;
540; 544; 557; 575; 576; 585; 588; 589; 604; 605; 609; 617; 619;
633; 645; 647; 651; 662; 683; 686; 687; 693; 698; 717; 725; 740;
742; 745; 779; 806; 819; 820; 827; 828; 835; 838; 846; 847; 848;
850; 875; 878; 879; 883; 888; 889; 891; 899; 900; 901; 902; 903;
909; 914; 937; 940; 946; 947; 981; 986; 994; 995; 1001; 1004; 1008;
1010; 1011; 1017; 1018; 1019; 1020; 1030; 1031; 1040; 1051; 1053;
1054; 1055; 1057; 1058; 1061; 1062; 1071; 1081; 1098; 1102; 1104;
1105; 1115; 1119; 1120; 1122; 1127; 1128 and mixtures thereof,
preferably said malodor reduction material is selected from the
group consisting of Table 1 materials 3; 4; 7; 9; 21; 25; 29; 30;
32; 34; 35; 42; 49; 65; 67; 70; 92; 93; 101; 102; 103; 114; 123;
126; 130; 142; 145; 149; 155; 159; 167; 168; 170; 178; 186; 189;
192; 193; 208; 209; 210; 218; 228; 229; 231; 256; 267; 274; 278;
280; 281; 290; 294; 317; 318; 322; 325; 333; 338; 342; 344; 358;
362; 364; 386; 397; 398; 415; 421; 424; 436; 441; 444; 445; 449;
461; 466; 468; 471; 473; 475; 491; 519; 520; 527; 531; 534; 544;
565; 586; 587; 589; 603; 604; 606; 609; 611; 612; 614; 615; 618;
621; 627; 628; 631; 632; 633; 639; 659; 683; 686; 692; 693; 696;
698; 702; 708; 711; 714; 715; 717; 720; 725; 742; 748; 750; 752;
763; 766; 768; 774; 778; 781; 786; 791; 800; 802; 806; 814; 821;
826; 827; 828; 850; 852; 866; 868; 871; 873; 876; 877; 878; 879;
884; 897; 905; 914; 926; 937; 946; 947; 950; 973; 974; 982; 1006;
1008; 1010; 1016; 1020; 1031; 1037; 1043; 1045; 1053; 1057; 1060;
1062; 1102; 1104; 1105; 1120; 1125; 1137; 1144; 1145 and Table 2
materials 565: 631; 659; 715 and mixtures thereof, preferably said
malodor reduction material is selected from the group consisting of
Table 4 materials 7; 229; 281; 441; 603; 621; 627; 632; 696; 708;
714; 750; 1060; 1137; 1144; 1145, Table 5 material 526 and mixtures
thereof. These are materials that are stable in perfume particles
as they do not leak and will volatilize more quickly into the air
because they are lower VP when the delivery system releases them
thus being able to block the perception of the malodor better on
the substrate the delivery system is near to or in contact
with.
[0046] A consumer product comprising delivery system disclosed by
Applicants herein and a consumer product ingredient is
disclosed.
[0047] A method of treating and/or cleaning a situs, said method
comprising [0048] a) optionally washing, rinsing and/or drying said
situs; [0049] b) contacting said situs with a delivery system
according to claims 1-12 and/or a consumer product according to
claim 13; and [0050] c) optionally washing, rinsing and/or drying
said situs is disclosed.
[0051] A situs treated with a delivery system disclosed herein
and/or a consumer product disclosed herein is disclosed.
Process of Making Encapsulates
[0052] In one aspect, a process that may comprise: [0053] a.)
preparing a first solution that may comprise, based on total
solution weight from about 20% to about 90%, from about 40% to
about 80%, or even from about 60% to about 80% water, of a first
emulsifier and a first resin, the ratio of said first emulsifier
and said first resin being from about 0.1:0 to about 10:0, from
about 0.1:1 to about 10:1, from about 0.5:1 to about 3:1, or even
from about 0.8:1 to about 1.1:1; [0054] b.) preparing a second
solution that may comprise based on total solution weight from
about 20% to about 95% water, of a second emulsifier and a second
resin, the ratio of said second emulsifier and said second resin
being from about 0:1 to about 3:1, from about 0.04:1 to about
0.2:1, or even from about 0.05:1 to about 0.15:1; [0055] c.)
combining a core material that may comprise a perfume disclosed in
the present specification and said first solution to form a first
composition; [0056] d.) emulsifying said first composition; [0057]
e.) combining said first composition and said second solution to
form a second composition and optionally combining any processing
aids and said second composition--said first composition and said
second solution may be combined in any order but in one aspect said
second solution is added to said first composition or said second
solution and said first composition are combined simultaneously;
[0058] f.) mixing said second composition for at least 15 minutes,
at least 1 hour or even from about 4 hours to about 100 hours at a
temperature of from about 25.degree. C. to about 100.degree. C.,
from about 45.degree. C. to about 90.degree. C., or even from about
50.degree. C. to about 80.degree. C. heat and optionally combining
any processing aids to said second composition; [0059] g.)
optionally combining any scavenger material, structurant, and/or
anti-agglomeration agent with said second composition during step
f.) or thereafter--such materials may be combined in any order but
in one aspect the scavenger material is combined first, any
structurant second, and then anti-agglomeration agent is combined;
and [0060] h.) optionally spray drying said second composition
[0061] is disclosed.
[0062] In one or more aspects of the process, said first and second
resins may comprise the reaction product of an aldehyde and an
amine, suitable aldehydes include, formaldehyde. Suitable amines
include melamine, urea, benzoguanamine, glycoluril, and mixtures
thereof. Suitable melamines include, methylol melamine, methylated
methylol melamine, imino melamine and mixtures thereof. Suitable
ureas include, dimethylol urea, methylated dimethylol urea,
urea-resorcinol, and mixtures thereof.
[0063] In one or more aspects of the process, said first and second
emulsifiers may comprise a moiety selected from the group
consisting of carboxy, hydroxyl, thiol, amine, amide and
combinations thereof. In one aspect, said emulsifier may have a pKa
of less than 5, preferably greater than 0 but less than 5.
Emulsifiers include acrylic acid-alkyl acrylate copolymer,
poly(acrylic acid), polyoxyalkylene sorbitan fatty esters,
polyalkylene co-carboxy anhydrides, polyalkylene co-maleic
anhydrides, poly(methyl vinyl ether-co-maleic anhydride),
poly(propylene-co-maleic anhydride), poly(butadiene co-maleic
anhydride), and poly(vinyl acetate-co-maleic anhydride), polyvinyl
alcohols, polyalkylene glycols, polyoxyalkylene glycols, and
mixtures thereof.
[0064] In one or more aspects of the process, the pH of the first
and second solutions may be controlled such that the pH of said
first and second solution is from about 3.0 to 7.0.
[0065] In one or more aspects of the process, during step f.), from
about 0% to about 10%, from about 1% to about 5% or even from about
2% to about 4%, based on total second composition weight, of a salt
comprising an anion and cation, said anion being selected from the
group consisting of chloride, sulfate, phosphate, nitrate,
polyphosphate, citrate, maleate, fumarate and mixtures thereof; and
said cation being selected from the group consisting of a Periodic
Group IA element, Periodic Group IIA element, ammonium cation and
mixtures thereof, preferably sodium sulfate, may be combined with
said second composition.
[0066] In one or more aspects of the process, any of the
aforementioned processing parameters may be combined.
[0067] Supplemental teachings of making suitable encapsulates as
well as suitable shell materials are described in U.S. Pat. No.
6,869,923 B1 and US Published Patent Applications Nos. 2005/0276831
A1 and 2007/020263 A1. Suitable equipment for use in the processes
disclosed herein may include continuous stirred tank reactors,
homogenizers, turbine agitators, recirculating pumps, paddle
mixers, ploughshear mixers, ribbon blenders, vertical axis
granulators and drum mixers, both in batch and, where available, in
continuous process configurations, spray dryers, and extruders.
Such equipment can be obtained from Lodige GmbH (Paderborn,
Germany), Littleford Day, Inc. (Florence, Ky., U.S.A.), Forberg AS
(Larvik, Norway), Glatt Ingenieurtechnik GmbH (Weimar, Germany),
Niro (Soeborg, Denmark), Hosokawa Bepex Corp. (Minneapolis, Minn.,
U.S.A.), Arde Barinco (New Jersey, U.S.A.).
Compositions
[0068] In one aspect, a composition that may comprise any aspect of
the perfume delivery systems and/or perfumes disclosed in the
present specification is disclosed.
[0069] In one aspect, said composition may be a consumer
product.
[0070] In one aspect, such composition may be a consumer product
that may comprise, based on total composition weight, from about
0.001% to about 50%, from about 0.01% to about 10%, or even from
about 0.1% to about 5%, of a perfume disclosed in the present
specification--from about 0.001% to about 90%, from about 0.01% to
about 50%, or even from about 0.1% to about 10%, of said perfume,
based on said perfume's weight, may be provided by a perfume
delivery system according to the present specification.
[0071] In one aspect, said composition may comprise an encapsulate
wherein said encapsulate's density may be such that the density
ratio of said encapsulate to one or more fluids of the
composition's fluids may be from about 0.9:1 to about 1.1:1; from
about 0.98:1 to about 1.02:1; from about 0.99:1 to about 1.01:1 or
even 1:1.
[0072] In one aspect, any of the aforementioned compositions may
comprise a cleaning and/or treatment ingredient.
[0073] In one aspect, any of the aforementioned compositions'
encapsulates may be a perfume microcapsule.
[0074] In one aspect, any of the aforementioned compositions may
comprise one or more cleaning and/or treatment agents selected from
the adjunct ingredients listed in the present specification.
While the precise level of encapsulate that is employed depends on
the type and end use of the consumer product, in one aspect a
consumer product may comprise, based on total composition weight,
at least about 0.01%, from about 0.01% to about 80%, or even from
about 0.02% to about 10% wt % of a encapsulate disclosed
herein.
[0075] In one aspect, a consumer product that is compact is
disclosed.
[0076] In one aspect, a consumer products including liquid
detergents having a water content, based on total consumer product
formulation weight, of from about 0% to about 15%, from about 0.01%
to about 15%, from about 0.5% to about 10% or even from about 1% to
about 8% water are disclosed.
[0077] In one aspect, the consumer product is a cleaning and/or
treatment composition or fabric care composition that may comprise
an encapsulate disclosed in the present specification and at least
one cleaning and/or treatment composition or fabric care adjunct
ingredient.
[0078] In one aspect, a cleaning composition may comprise, from
about 0.005% to about 5% weight % of such encapsulate based on
total cleaning composition weight of such encapsulate. In one
aspect, a fabric treatment composition may comprise, based on total
fabric treatment composition weight from about 0.005% to about 20%
of such encapsulate.
[0079] Aspects of the invention include the use of the encapsulates
of the present invention in detergent compositions (e.g.,
TIDE.TM.), hard surface cleaners (e.g., MR CLEAN.TM.), automatic
dishwashing liquids (e.g., CASCADE.TM.), dishwashing liquids (e.g.,
DAWN.TM.), and floor cleaners (e.g., SWIFFER.TM.). The cleaning
compositions disclosed herein may be formulated such that, during
use in aqueous cleaning operations, the wash water will have a pH
of between about 6.5 and about 12, or between about 7.5 and 10.5.
Liquid dishwashing product formulations typically have a pH between
about 6.8 and about 9.0. Cleaning products are typically formulated
to have a pH of from about 2 to about 11. Techniques for
controlling pH at recommended usage levels include the use of
buffers, alkalis, acids, etc., and are well known to those skilled
in the art.
[0080] Fabric treatment compositions disclosed herein typically
comprise a fabric softening active ("FSA"). Suitable fabric
softening actives, include, but are not limited to, materials
selected from the group consisting of quats, amines, fatty esters,
sucrose esters, silicones, dispersible polyolefins, clays,
polysaccharides, fatty oils, polymer latexes and mixtures
thereof.
Formaldehyde Scavenger
[0081] In one aspect, the perfume delivery system disclosed herein
may be combined with a formaldehyde scavenger. In one aspect, such
perfume delivery system may comprise the encapsulates of the
present invention. Suitable formaldehyde scavengers include
materials selected from the group consisting of sodium bisulfite,
melamine, urea, ethylene urea, cysteine, cysteamine, lysine,
glycine, serine, carnosine, histidine, glutathione,
3,4-diaminobenzoic acid, allantoin, glycouril, anthranilic acid,
methyl anthranilate, methyl 4-aminobenzoate, ethyl acetoacetate,
acetoacetamide, malonamide, ascorbic acid, 1,3-dihydroxyacetone
dimer, biuret, oxamide, benzoguanamine, pyroglutamic acid,
pyrogallol, methyl gallate, ethyl gallate, propyl gallate,
triethanol amine, succinamide, thiabendazole, benzotriazol,
triazole, indoline, sulfanilic acid, oxamide, sorbitol, glucose,
cellulose, poly(vinyl alcohol), partially hydrolyzed
poly(vinylformamide), poly(vinyl amine), poly(ethylene imine),
poly(oxyalkyleneamine), poly(vinyl alcohol)-co-poly(vinyl amine),
poly(4-aminostyrene), poly(l-lysine), chitosan, hexane diol,
ethylenediamine-N,N'-bisacetoacetamide,
N-(2-ethylhexyl)acetoacetamide, 2-benzoylacetoacetamide,
N-(3-phenylpropyl)acetoacetamide, helional, melonal, Triplal.RTM.,
5,5-dimethyl-1,3-cyclohexanedione,
2,4-dimethyl-3-cyclohexenecarboxaldehyde,
2,2-dimethyl-1,3-dioxan-4,6-dione, 2-pentanone, dibutyl amine,
triethylenetetramine, ammonium hydroxide, benzylamine,
hydroxycitronellol, cyclohexanone, 2-butanone, pentane dione,
dehydroacetic acid, or a mixture thereof. These formaldehyde
scavengers may be obtained from Sigma/Aldrich/Fluka of St. Louis,
Mo. U.S.A. or PolySciences, Inc. of Warrington, Pa., U.S.A.
[0082] Such formaldehyde scavengers are typically combined with a
slurry containing said benefit agent containing delivery particle,
at a level, based on total slurry weight, of from about 2 wt. % to
about 18 wt. %, from about 3.5 wt. % to about 14 wt. % or even from
about 5 wt. % to about 13 wt. %.
[0083] In one aspect, such formaldehyde scavengers may be combined
with a product containing a benefit agent containing delivery
particle, said scavengers being combined with said product at a
level, based on total product weight, of from about 0.005% to about
0.8%, alternatively from about 0.03% to about 0.5%, alternatively
from about 0.065% to about 0.25% of the product formulation.
Consumer Product Ingredients
[0084] While not essential for each consumer product embodiment of
the present invention, the non-limiting list of adjuncts
illustrated hereinafter are suitable for use in the instant
consumer products and may be desirably incorporated in certain
embodiments of the invention, for example to assist or enhance
performance, for treatment of the substrate to be cleaned, or to
modify the aesthetics of the composition as is the case with
perfumes, colorants, dyes or the like. The precise nature of these
additional components, and levels of incorporation thereof, will
depend on the physical form of the composition and the nature of
the operation for which it is to be used. Such adjunct are in
addition to the perfumes and/or perfume delivery systems previously
disclosed herein. Suitable adjunct materials include, but are not
limited to, surfactants, builders, chelating agents, dye transfer
inhibiting agents, dispersants, enzymes, and enzyme stabilizers,
catalytic materials, bleach activators, polymeric dispersing
agents, clay soil removal/anti-redeposition agents, brighteners,
suds suppressors, dyes, additional perfume and perfume delivery
systems, structure elasticizing agents, thickeners/structurants,
fabric softeners, carriers, hydrotropes, processing aids and/or
pigments.
[0085] As stated, the adjunct ingredients are not essential for
each consumer product embodiment of the present invention. Thus,
certain embodiments of Applicants' compositions do not contain one
or more of the following adjuncts materials: bleach activators,
surfactants, builders, chelating agents, dye transfer inhibiting
agents, dispersants, enzymes, and enzyme stabilizers, catalytic
metal complexes, polymeric dispersing agents, clay and soil
removal/anti-redeposition agents, brighteners, suds suppressors,
dyes, additional perfumes and perfume delivery systems, structure
elasticizing agents, thickeners/structurants, fabric softeners,
carriers, hydrotropes, processing aids and/or pigments. However,
when one or more adjuncts are present, such one or more adjuncts
may be present as detailed below:
[0086] Surfactants--The compositions according to the present
invention can comprise a surfactant or surfactant system wherein
the surfactant can be selected from nonionic and/or anionic and/or
cationic surfactants and/or ampholytic and/or zwitterionic and/or
semi-polar nonionic surfactants. The surfactant is typically
present at a level of from about 0.1%, from about 1%, or even from
about 5% by weight of the cleaning compositions to about 99.9%, to
about 80%, to about 35%, or even to about 30% by weight of the
cleaning compositions.
[0087] Builders--The compositions of the present invention can
comprise one or more detergent builders or builder systems. When
present, the compositions will typically comprise at least about 1%
builder, or from about 5% or 10% to about 80%, 50%, or even 30% by
weight, of said builder. Builders include, but are not limited to,
the alkali metal, ammonium and alkanolammonium salts of
polyphosphates, alkali metal silicates, alkaline earth and alkali
metal carbonates, aluminosilicate builders, polycarboxylate
compounds, ether hydroxypolycarboxylates, copolymers of maleic
anhydride with ethylene or vinyl methyl ether,
1,3,5-trihydroxybenzene-2,4,6-trisulphonic acid, and
carboxymethyl-oxysuccinic acid, the various alkali metal, ammonium
and substituted ammonium salts of polyacetic acids such as
ethylenediamine tetraacetic acid and nitrilotriacetic acid, as well
as polycarboxylates such as mellitic acid, succinic acid,
oxydisuccinic acid, polymaleic acid, benzene 1,3,5-tricarboxylic
acid, carboxymethyloxysuccinic acid, and soluble salts thereof.
[0088] Chelating Agents--The compositions herein may also
optionally contain one or more copper, iron and/or manganese
chelating agents. If utilized, chelating agents will generally
comprise from about 0.1% by weight of the compositions herein to
about 15%, or even from about 3.0% to about 15% by weight of the
compositions herein.
[0089] Dye Transfer Inhibiting Agents--The compositions of the
present invention may also include one or more dye transfer
inhibiting agents. Suitable polymeric dye transfer inhibiting
agents include, but are not limited to, polyvinylpyrrolidone
polymers, polyamine N-oxide polymers, copolymers of
N-vinylpyrrolidone and N-vinylimidazole, polyvinyloxazolidones and
polyvinylimidazoles or mixtures thereof. When present in the
compositions herein, the dye transfer inhibiting agents are present
at levels from about 0.0001%, from about 0.01%, from about 0.05% by
weight of the cleaning compositions to about 10%, about 2%, or even
about 1% by weight of the cleaning compositions.
[0090] Dispersants--The compositions of the present invention can
also contain dispersants. Suitable water-soluble organic materials
are the homo- or co-polymeric acids or their salts, in which the
polycarboxylic acid may comprise at least two carboxyl radicals
separated from each other by not more than two carbon atoms.
[0091] Enzymes--The compositions can comprise one or more detergent
enzymes which provide cleaning performance and/or fabric care
benefits. Examples of suitable enzymes include, but are not limited
to, hemicellulases, peroxidases, proteases, cellulases, xylanases,
lipases, phospholipases, esterases, cutinases, pectinases,
keratanases, reductases, oxidases, phenoloxidases, lipoxygenases,
ligninases, pullulanases, tannases, pentosanases, malanases,
.beta.-glucanases, arabinosidases, hyaluronidase, chondroitinase,
laccase, and amylases, or mixtures thereof. A typical combination
is a cocktail of conventional applicable enzymes like protease,
lipase, cutinase and/or cellulase in conjunction with amylase.
[0092] Enzyme Stabilizers--Enzymes for use in compositions, for
example, detergents can be stabilized by various techniques. The
enzymes employed herein can be stabilized by the presence of
water-soluble sources of calcium and/or magnesium ions in the
finished compositions that provide such ions to the enzymes.
[0093] Catalytic Metal Complexes--Applicants' compositions may
include catalytic metal complexes. One type of metal-containing
bleach catalyst is a catalyst system comprising a transition metal
cation of defined bleach catalytic activity, such as copper, iron,
titanium, ruthenium, tungsten, molybdenum, or manganese cations, an
auxiliary metal cation having little or no bleach catalytic
activity, such as zinc or aluminum cations, and a sequestrate
having defined stability constants for the catalytic and auxiliary
metal cations, particularly ethylenediaminetetraacetic acid,
ethylenediaminetetra (methyl-enephosphonic acid) and water-soluble
salts thereof.
[0094] If desired, the compositions herein can be catalyzed by
means of a manganese compound. Such compounds and levels of use are
well known in the art.
[0095] Compositions herein may also suitably include a transition
metal complex of a macropolycyclic rigid ligand--abbreviated as
"MRL". As a practical matter, and not by way of limitation, the
compositions and cleaning processes herein can be adjusted to
provide on the order of at least one part per hundred million of
the benefit agent MRL species in the aqueous washing medium, and
may provide from about 0.005 ppm to about 25 ppm, from about 0.05
ppm to about 10 ppm, or even from about 0.1 ppm to about 5 ppm, of
the MRL in the wash liquor.
[0096] Preferred transition-metals in the instant transition-metal
bleach catalyst include manganese, iron and chromium. Preferred
MRL's herein are a special type of ultra-rigid ligand that is
cross-bridged such as
5,12-diethyl-1,5,8,12-tetraazabicyclo[6.6.2]hexa-decane.
[0097] Rheology Modifier
[0098] The liquid compositions of the present invention may
comprise a rheology modifier. The rheology modifier may be selected
from the group consisting of non-polymeric crystalline,
hydroxy-functional materials, polymeric rheology modifiers which
impart shear thinning characteristics to the aqueous liquid matrix
of the composition. In one aspect, such rheology modifiers impart
to the aqueous liquid composition a high shear viscosity, at 20
sec.sup.-1 shear rate and at 21.degree. C., of from 1 to 7000 mPas
and a viscosity at low shear (0.5 sec.sup.-1 shear rate at
21.degree. C.) of greater than 1000 mPas, or even 1000 mPas to
200,000 mPas. In one aspect, for cleaning and treatment
compositions, such rheology modifiers impart to the aqueous liquid
composition a high shear viscosity, at 20 sec.sup.-1 and at
21.degree. C., of from 50 to 3000 mPas and a viscosity at low shear
(0.5 sec.sup.-1 shear rate at 21.degree. C.) of greater than 1000
mPas, or even 1000 mPas to 200,000 mPas. Viscosity according to the
present invention is measured using an AR 2000 rheometer from TA
instruments using a plate steel spindle having a plate diameter of
40 mm and a gap size of 500 .mu.m. The high shear viscosity at 20
sec.sup.-1 and low shear viscosity at 0.5 sec.sup.-1 can be
obtained from a logarithmic shear rate sweep from 0.1 sec.sup.-1 to
25 sec.sup.-1 in 3 minutes time at 21.degree. C. Crystalline
hydroxyl functional materials are rheology modifiers which form
thread-like structuring systems throughout the matrix of the
composition upon in situ crystallization in the matrix. Polymeric
rheology modifiers are preferably selected from polyacrylates,
polymeric gums, other non-gum polysaccharides, and combinations of
these polymeric materials.
[0099] Generally the rheology modifier will comprise from 0.01% to
1% by weight, preferably from 0.05% to 0.75% by weight, more
preferably from 0.1% to 0.5% by weight, of the compositions
herein.
[0100] Structuring agents which are especially useful in the
compositions of the present invention may comprise non-polymeric
(except for conventional alkoxylation), crystalline
hydroxy-functional materials which can form thread-like structuring
systems throughout the liquid matrix when they are crystallized
within the matrix in situ. Such materials can be generally
characterized as crystalline, hydroxyl-containing fatty acids,
fatty esters or fatty waxes. In one aspect, rheology modifiers
include crystalline, hydroxyl-containing rheology modifiers include
castor oil and its derivatives. In one aspect, rheology modifiers
include hydrogenated castor oil derivatives such as hydrogenated
castor oil and hydrogenated castor wax. Commercially available,
castor oil-based, crystalline, hydroxyl-containing rheology
modifiers include THIXCIN.TM. from Rheox, Inc. (now Elementis).
[0101] Other types of rheology modifiers, besides the
non-polymeric, crystalline, hydroxyl-containing rheology modifiers
described heretofore, may be utilized in the liquid detergent
compositions herein. Polymeric materials which provide
shear-thinning characteristics to the aqueous liquid matrix may
also be employed.
[0102] Suitable polymeric rheology modifiers include those of the
polyacrylate, polysaccharide or polysaccharide derivative type.
Polysaccharide derivatives typically used as rheology modifiers
comprise polymeric gum materials. Such gums include pectine,
alginate, arabinogalactan (gum Arabic), carrageenan, gellan gum,
xanthan gum and guar gum.
[0103] If polymeric rheology modifiers are employed herein, a
preferred material of this type is gellan gum. Gellan gum is a
heteropolysaccharide prepared by fermentation of Pseudomonaselodea
ATCC 31461. Gellan gum is commercially marketed by CP Kelco U.S.,
Inc. under the KELCOGEL tradename.
[0104] A further alternative and suitable rheology modifier include
a combination of a solvent and a polycarboxylate polymer. More
specifically the solvent may be an alkylene glycol. In one aspect,
the solvent may comprise dipropylene glycol. In one aspect, the
polycarboxylate polymer may comprise a polyacrylate,
polymethacrylate or mixtures thereof. In one aspect, solvent may be
present, based on total composition weight, at a level of from 0.5%
to 15%, or from 2% to 9% of the composition. In one aspect,
polycarboxylate polymer may be present, based on total composition
weight, at a level of from 0.1% to 10%, or from 2% to 5%. In one
aspect, the solvent component may comprise mixture of dipropylene
glycol and 1,2-propanediol. In one aspect, the ratio of dipropylene
glycol to 1,2-propanediol may be 3:1 to 1:3, or even 1:1. In one
aspect, the polyacrylate may comprise a copolymer of unsaturated
mono- or di-carbonic acid and C.sub.1-C.sub.30 alkyl ester of the
(meth) acrylic acid. In another aspect, the rheology modifier may
comprise a polyacrylate of unsaturated mono- or di-carbonic acid
and C.sub.1-C.sub.30 alkyl ester of the (meth) acrylic acid. Such
copolymers are available from Noveon Inc. under the tradename
Carbopol Aqua 30.RTM..
[0105] In the absence of rheology modifier and in order to impart
the desired shear thinning characteristics to the liquid
composition, the liquid composition can be internally structured
through surfactant phase chemistry or gel phases.
Processes of Making and Using Consumer Products
[0106] The embodiments of consumer products of the present
invention can be formulated into any suitable form and prepared by
any process chosen by the formulator, non-limiting examples of
which are described in U.S. Pat. No. 5,879,584; which is
incorporated herein by reference.
[0107] In one aspect, the perfumes and/or delivery systems
comprising same that are disclosed herein may be incorporated into
solid particles, particularly polymeric based particles. Preferably
said perfume delivery system is a microcapsule that comprises said
perfume one or more of said perfumes. Examples of such polymeric
particles may include particles comprising polyethylene glycol,
starches and polysaccharides, polyvinyl alcohol, celluloses. Such
particles may additionally comprise additional components such as
other benefit agents, inorganic fillers such as carbonate,
silicate, clay, metal oxides. Particularly useful particles include
particles based on polyethylene glycol.
Method of Use
[0108] Compositions, such as consumer products, containing the
encapsulate disclosed herein can be used to clean or treat a situs
inter alia a surface or fabric. Typically at least a portion of the
situs is contacted with an embodiment of Applicants' composition,
in neat form or diluted in a liquor, for example, a wash liquor and
then the situs may be optionally washed and/or rinsed. In one
aspect, a situs is optionally washed and/or rinsed, contacted with
an encapsulate according to the present invention or composition
comprising said encapsulate and then optionally washed and/or
rinsed. For purposes of the present invention, washing includes but
is not limited to, scrubbing, and mechanical agitation. The situs
may comprise most any material, for example a fabric, fabric
capable of being laundered or treated in normal consumer use
conditions. Liquors that may comprise the disclosed compositions
may have a pH of from about 3 to about 11.5. Such compositions are
typically employed at concentrations of from about 500 ppm to about
15,000 ppm in solution. When the wash solvent is water, the water
temperature typically ranges from about 5.degree. C. to about
90.degree. C. and, when the situs comprises a fabric, the water to
fabric ratio is typically from about 1:1 to about 30:1.
Test Methods
[0109] Malodor reduction materials may be separated from mixtures,
including but not limited to finished products such as consumer
products and indentified, by analytical methods that include GC-MS
and/or NMR.
Test for Volume Weighted Mean Particle Size
[0110] Particle size is measured using an Accusizer 780A, made by
Particle Sizing Systems, Santa Barbara Calif. The instrument is
calibrated from 0 to 300.mu. using Duke particle size standards.
Samples for particle size evaluation are prepared by diluting about
1 g emulsion, if the volume weighted mean particle size of the
emulsion is to be determined, or 1 g of capsule slurry, if the
finished capsule volume weighted mean particle size is to be
determined, in about 5 g of de-ionized water and further diluting
about 1 g of this solution in about 25 g of water. [0111] About 1 g
of the most dilute sample is added to the Accusizer and the testing
initiated, using the autodilution feature. The Accusizer should be
reading in excess of 9200 counts/second. If the counts are less
than 9200 additional sample should be added. The accusizer will
dilute the test sample until 9200 counts/second and initiate the
evaluation. After 2 minutes of testing the Accusizer will display
the results, including volume-weighted median size. The broadness
index can be calculated by determining the particle size at which
95% of the cumulative particle volume is exceeded (95% size), the
particle size at which 5% of the cumulative particle volume is
exceeded (5% size), and the median volume-weighted particle size
(50% size-50% of the particle volume both above and below this
size). Broadness Index (5)=((95% size)-(5% size)/50% size).
Test Method for Determining Saturation Vapour Pressure (VP)
[0112] The saturation Vapour Pressure (VP) values are computed for
each PRM in the perfume mixture being tested. The VP of an
individual PRM is calculated using the VP Computational Model,
version 14.02 (Linux) available from Advanced Chemistry Development
Inc. (ACD/Labs) (Toronto, Canada) to provide the VP value at
25.degree. C. expressed in units of torr. The ACD/Labs' Vapor
Pressure model is part of the ACD/Labs model suite.
Test Method for Determining the Logarithm of the Octanol/Water
Partition Coefficient (log P)
[0113] The value of the log of the Octanol/Water Partition
Coefficient (log P) is computed for each PRM in the perfume mixture
being tested. The log P of an individual PRM is calculated using
the Consensus log P Computational Model, version 14.02 (Linux)
available from Advanced Chemistry Development Inc. (ACD/Labs)
(Toronto, Canada) to provide the unitless log P value. The
ACD/Labs' Consensus log P Computational Model is part of the
ACD/Labs model suite.
Test Method for the Generation of Molecular Descriptors
[0114] In order to conduct the calculations involved in the
computed-value test methods described herein, the starting
information required includes the identity, weight percent, and
molar percent of each PRM in the perfume being tested, as a
proportion of that perfume, wherein all PRMs in the perfume
composition are included in the calculations. Additionally for each
of those PRMs, the molecular structure, and the values of various
computationally-derived molecular descriptors are also required, as
determined in accordance with the Test Method for the Generation of
Molecular Descriptors described herein.
[0115] For each PRM in a perfume mixture or composition, its
molecular structure is used to compute various molecular
descriptors. The molecular structure is determined by the graphic
molecular structure representations provided by the Chemical
Abstract Service ("CAS"), a division of the American Chemical
Society, Columbus, Ohio, U.S.A. These molecular structures may be
obtained from the CAS Chemical Registry System database by looking
up the index name or CAS number of each PRM. For PRMs, which at the
time of their testing are not yet listed in the CAS Chemical
Registry System database, other databases or information sources
may be used to determine their structures. For a PRM which has
potentially more than one isomer present, the molecular descriptor
computations are conducted using the molecular structure of only
one of the isomers, which is selected to represent that PRM. The
selection of isomer is determined by the relative amount of
extension in the molecular structures of the isomers. Of all the
isomers of a given PRM, it is the isomer whose molecular structure
that is the most prevalent which is the one that is selected to
represent that PRM. The structures for other potential isomers of
that PRM are excluded from the computations. The molecular
structure of the isomer that is the most prevalent is paired with
the concentration of that PRM, where the concentration reflects the
presence of all the isomers of that PRM that are present.
[0116] A molecule editor or molecular sketching software program,
such as ChemDraw (CambridgeSoft/PerkinElmer Inc., Waltham, Mass.,
U.S.A.), is used to duplicate the 2-dimensional molecular structure
representing each PRM. Molecular structures should be represented
as neutral species (quaternary nitrogen atoms are allowed) with no
disconnected fragments (e.g., single structures with no counter
ions). The winMolconn program described below can convert any
deprotonated functional groups to the neutral form by adding the
appropriate number of hydrogen atoms and will discard the counter
ion.
[0117] For each PRM, the molecular sketching software is used to
generate a file which describes the molecular structure of the PRM.
The file(s) describing the molecular structures of the PRMs is
subsequently submitted to the computer software program winMolconn,
version 1.0.1.3 (Hall Associates Consulting, Quincy, Mass., U.S.A.,
www.molconn.com), in order to derive various molecular descriptors
for each PRM. As such, it is the winMolconn software program which
dictates the structure notations and file formats that are
acceptable options. These options include either a MACCS SDF
formatted file (i.e., a Structure-Data File); or a Simplified
Molecular Input Line Entry Specification (i.e., a SMILES string
structure line notation) which is commonly used within a simple
text file, often with a ".smi" or ".txt" file name extension. The
SDF file represents each molecular structure in the format of a
multi-line record, while the syntax for a SMILES structure is a
single line of text with no white space. A structure name or
identifier can be added to the SMILES string by including it on the
same line following the SMILES string and separated by a space,
e.g.: C1=CC=CC=C1 benzene.
[0118] The winMolconn software program is used to generate numerous
molecular descriptors for each PRM, which are then output in a
table format. Specific molecular descriptors derived by winMolconn
are subsequently used as inputs (i.e., as variable terms in
mathematical equations) for a variety of computer model test
methods in order to calculate values such as: saturation Vapour
Pressure (VP); Boiling Point (BP); logarithm of the Octanol/Water
Partition Coefficient (log P); Odour Detection Threshold (ODT);
Malodour Reduction Value (MORV); and/or Universal Malodour
Reduction Value (Universal MORV) for each PRM. The molecular
descriptor labels used in the models' test method computations are
the same labels reported by the winMolconn program, and their
descriptions and definitions can be found listed in the winMolconn
documentation. The following is a generic description of how to
execute the winMolconn software program and generate the required
molecular structure descriptors for each PRM in a composition.
[0119] Computing Molecular Structure Descriptors using winMolconn:
[0120] 1) Assemble the molecular structure for one or more perfume
ingredients in the form of a MACCS Structure-Data File, also called
an SDF file, or as a SMILES file. [0121] 2) Using version 1.0.1.3
of the winMolconn program, running on an appropriate computer,
compute the full complement of molecular descriptors that are
available from the program, using the SDF or SMILES file described
above as input. [0122] a. The output of winMolconn is in the form
of an ASCII text file, typically space delimited, containing the
structure identifiers in the first column and respective molecular
descriptors in the remaining columns for each structure in the
input file. [0123] 3) Parse the text file into columns using a
spreadsheet software program or some other appropriate technique.
The molecular descriptor labels are found on the first row of the
resulting table. [0124] 4) Find and extract the descriptor columns,
identified by the molecular descriptor label, corresponding to the
inputs required for each model. [0125] a. Note that the winMolconn
molecular descriptor labels are case-sensitive.
MORV and Universal MORV Calculation
[0125] [0126] 1.) Input Molecular Descriptor values as determined
via the method above into the following four equations:
[0126]
MORV=-8.5096+2.8597.times.(dxp9)+1.1253.times.(knotpv)-0.34484.ti-
mes.(e1C2O2)-0.00046231.times.(idw)+3.3509.times.(idcbar)+0.11158.times.(n-
2pag22) a)
MORV=-5.2917+2.1741.times.(dxvp5)-2.6595.times.(dxvp8)+0.45297.times.(e1-
C2C2d)-0.6202.times.(c1C2O2)+1.3542.times.(CdCH2)+0.68105.times.(CaasC)+1.-
7129.times.(idcbar) b)
MORV=-0.0035+0.8028.times.(SHCsatu)+2.1673.times.(xvp7)-1.3507.times.(c1-
C1C3d)+0.61496.times.(c1C1O2)+0.00403.times.(idc)-0.23286.times.(nd2).
c)
MORV=-0.9926-0.03882.times.(Sd0)+0.1869.times.(Ssp3OH)+2.1847.times.(xp7-
)+0.34344.times.(e1C302)-0.45767.times.(c1C2C3)+0.7684.times.(CKetone)
d)
Equation a) relates a material's effectiveness in reducing the
malodor trans-3-methyl-2-hexenoic acid (carboxylic acid based
malodors) Equation b) relates a material's effectiveness in
reducing the malodor trimethylamine (amine based malodors) Equation
c) relates a material's effectiveness in reducing the malodor
3-mercapto-3-methylhexan-1-ol (thiol based malodors) Equation d)
relates a material's effectiveness in reducing the malodor skatole
(indole based malodors) [0127] 2.) For purpose of the present
application, a material's MORV is the highest MORV value from
equations 1.)a) through 1.)d). [0128] 3.) If all MORV values from
equations 1.)a) through 1.)d) above are greater than 0.5, the
subject material has a Universal MORV.
Method for Assigning Fragrance Fidelity Index (FFI) and the Blocker
Index (BI) for a Malodor Reduction Compound
[0129] Blocker materials suitable for use in consumer products of
the present invention are chosen for their ability to decrease
malodor, while not interfering with perception of a fragrance.
Material selection is done by assigning two indices to a test
sample material from two reference scales in order to rank odor
strengths. The two reference scales are the Fragrance Fidelity
Index (FFI) scale and the Blocker Index (BI) scale. The FFI ranks
the ability of the test sample material to impart a perceivable
odor which could cause interference when combined with another
fragrance and the BI ranks the ability of the test sample material
to reduce malodor perception. The two methods for assigning the
indices to a test sample on the FFI and the BI reference scales are
given below.
Method for Assigning the FFI to Test Samples
[0130] The first step in the method for assigning an FFI to the
test samples on the FFI reference scale is to create the FFI
reference swatches. The swatches for the scale are created by
treating clean fabrics swatches with a known amount of a known
concentration of an ethyl vanillin solution. Fabric swatches for
this test are white knit polycotton (4 inch.times.4 inch) swatches
from EMC ordered as PC 50/50. The supplier is instructed to strip
the swatches first, stripping involves washing twice with a
fragrance-free detergent and rinsing three times.
Making the FFI Reference Swatches
[0131] Make three solutions of ethyl vanillin using a 50%/50%
EtOH/water as the diluent at the following concentrations: 25 ppm,
120 ppm and 1000 ppm. Pipette 13 .mu.L of each of the three
solutions into the middle of a clean swatch resulting in about a 1
cm diameter of the solution in the middle of the swatch. This will
create a sensory scale of three swatches with three different odor
levels based on the concentration of the solution pipetted onto the
swatch. After drying for 30 minutes in a vented hood, the swatches
are wrapped in aluminum foil to prevent odor contamination to the
treated swatch. A clean untreated swatch is also included as the
lowest anchor point of reference for odor strength on the FPI
scale. The FFI reference scale swatches should be used within 0.5
to 12 hours and discarded after 12 hours. The swatches are used as
scale anchor points when graders evaluate a test sample(s) and are
assigned a Fragrance Fidelity Index (FFI) as show in Table 7.
[0132] At least four perfumers/expert graders are used to rank the
ethyl vanillin swatches in the FFI scale. The perfumer/expert
grader needs to demonstrate adequate discrimination on the scale.
The perfumer/expert panel is asked to rank order swatches according
to a scale between 0 and 3. The panel must demonstrate statistical
differences between the swatches as seen in Table 7.
TABLE-US-00009 TABLE 7 Results FFI of reference swatches from six
perfumers/expert graders. Expert Grader Std FFI Swatch 1 2 3 4 5 6
Ave Dev. 0 Control: stripped 0 0 0.5 0 0 0 0.08 0.2 swatch NIL
ethyl vanillin 1 Stripped swatch with 0.5 0.5 0.5 1.5 0.5 1.0 0.75
0.4 13 .mu.L 25 ppm ethyl vanillin 2 Stripped swatch with 2.0 1.5
1.5 2.0 2.0 2.0 1.8 0.2 13 .mu.L 120 ppm ethyl vanillin 3 Stripped
swatch with 3.0 2.0 3.0 3.0 3.0 3.0 2.8 0.4 13 .mu.L 1000 ppm ethyl
vanillin
[0133] The expert graders must demonstrate a full range of 2.5 over
the 4 swatches to be acceptably discriminating. Grader 2 in table 1
has a range of only 2 and is eliminated from the panel. The panel
of expert graders must also demonstrated the ability to
statistically discriminate between swatches in the scale.
TABLE-US-00010 TABLE 8 This table demonstrates acceptable expert
graders with an acceptable range and the panel meets the
requirement for discriminating statistics. Expert Grader Std FFI
Swatch 1 3 4 5 6 Ave Dev. 0 Control: stripped swatch 0 0.5 0 0 0
0.08 0.2 NIL ethyl vanillin 1 Stripped swatch with 13 0.5 0.5 1.5
0.5 1.0 0.80 0.4 .mu.L 25 ppm ethyl vanillin 2 Stripped swatch with
13 2.0 1.5 2.0 2.0 2.0 1.9 0.2 .mu.L 120 ppm ethyl vanillin 3
Stripped swatch with 13 3.0 3.0 3.0 3.0 3.0 3.0 0.0 .mu.L 1000 ppm
ethyl vanillin
[0134] The reference swatches represent the 0, 1, 2, and 3 FFIs on
the FFI reference scale, Table 9. The expert grader should
familiarize them self with the strength of the odor on the FFI
reference swatches by sniffing each one starting at 0 (the lowest
odor strength) and ending at 3 (the highest odor strength). This
should be done prior to evaluating the test sample material treated
swatch.
TABLE-US-00011 TABLE 9 Swatch treatments comprising the Fragrance
Fidelity Index (FFI) reference scale Swatch treatment Conc. of
ethyl vanillin FFI Clean fabric swatch 1000 ppm ethyl vanillin 3
w/13 .mu.L ethyl vanillin Clean fabric swatch 120 ppm ethyl
vanillin 2 w/13 .mu.L ethyl vanillin Clean fabric swatch 25 ppm
ethyl vanillin 1 w/13 .mu.L ethyl vanillin Clean fabric swatch NIL
ethyl vanillin NIL ethyl vanillin 0
Making Swatches Treated with the Test Material
[0135] A clean swatch is treated with 13 .mu.L of a known
concentration of a test sample material resulting in an about 1 cm
of the solution on the clean swatch. Just like the reference
swatches, the test sample material swatch is dried in a vented hood
for 30 minutes and then wrapped in aluminum foil to prevent
contamination. The test material swatches and the FFI reference
swatches should be made within 2 hrs of each other. The test
material swatch must be used within 0.5 to 12 hours and discarded
after 12 hours.
Assigning the FFI to the Test Material
[0136] At least two perfumers/expert graders are used to assign an
FFI grade to a test sample. The perfumer/expert grader smells the
test sample swatch by holding that swatch 1 inch from their nose
with their nose centered over the area where the test sample was
pipetted on to the fabric and then assigns the test sample an FFI
grade using the FFI reference scale anchor swatches as references.
The test sample swatch is assigned an FPI grade at or between
numbers on the FFI scale shown in Table 9. In cases where the test
sample material is graded greater than 3, the test material is not
a blocker material or the concentration of the material needs to be
lowered and reevaluated to determine if a lower level has a malodor
blocker functionality.
Method for Assigning the BI to Test Sample
[0137] The first step in the method for assigning a BI to a test
sample material on the BI reference scale is to create the BI
reference swatches. The swatches for the scale are created by
treating clean fabrics swatches with a known amount of a known
volume of isovaleric acid solution at a known concentration. Fabric
swatches for this test are white knit polycotton (4 inch.times.4
inch) swatches from EMC ordered as PC 50/50. The supplier is
instructed to strip the swatches first, stripping involves washing
twice with a fragrance-free detergent and rinsing three times.
Making the BI Reference Swatches
[0138] Make one solution of 0.08% isovaleric acid using 50%/50%
EtOH/water as the diluent. The BI scale contains one clean swatch
with no malodor applied. Three other swatches each have a different
volume of the 0.08% isovaleric acid applied. Pipette 2 .mu.L of the
0.08% isovaleric acid solution to one clean swatch, 5 .mu.L of the
0.08% isovaleric acid solution to the next swatch and 20 .mu.L of
isovaleric acid to the final clean swatch. These solutions are
pipetted to the middle of the swatches. This will create a sensory
scale of three swatches with three different odor levels based on
the volume of the 0.08% isovaleric acid solution pipetted onto the
swatch. After drying for 30 minutes in a vented hood, the swatches
are wrapped in aluminum foil to prevent odor contamination to the
treated swatch. A clean untreated swatch is also included as the
lowest anchor point of reference for malodor strength on the BI
scale. The BI reference scale swatches should be used within 0.5 to
12 hours and discarded after 12 hours. The swatches are used as
scale anchor points when graders evaluate a test sample(s) and are
assigned a Blocker Index (BI) as show in Table 12.
[0139] At least four perfumers/expert graders are used to rank the
isovaleric acid swatches in the BI scale. The perfumer/expert
grader needs to demonstrate adequate discrimination on the scale.
The perfumer/expert grader is asked to rank order swatches
according to a scale between 0 and 3. The panel of graders must
demonstrate statistical differences between the swatches as seen in
Table 10.
TABLE-US-00012 TABLE 10 Results from six perfumers/expert graders
to create the BI scale. Expert Grader Std BI Swatch 1 2 3 4 5 Ave
Dev. 0 Control: stripped swatch 0 0 0 0 0 0 0 NIL isovaleric acid 1
Stripped swatch with 2 0.5 2.0 1.0 1.0 0.5 1.0 0.5 .mu.L 0.08%
isovaleric acid 2 Stripped swatch with 5 2.0 2.5 2.0 2.0 2.0 2.1
0.2 .mu.L 0.08% isovaleric acid 3 Stripped swatch with 20 3.0 3.0
3.0 3.0 2.5 2.8 0.2 .mu.L 0.08% isovaleric acid
[0140] The expert graders must demonstrate a full range of 2.5 over
the 4 swatches to be acceptably discriminating. The panel of expert
graders must also demonstrated the ability to statistically
discriminate between swatches in the scale. Expert grader #2 did
not demonstrate the ability to discriminate between the swatches
and is eliminated from the panel, see Table 11.
TABLE-US-00013 TABLE 11 This table demonstrates acceptable expert
graders with an acceptable range and the panel meets the
requirement for discriminating statistics. Expert Grader Std BI
Swatch 1 3 4 5 Ave Dev. 0 Control: stripped swatch 0 0 0 0 0 0 NIL
isovaleric acid 1 Stripped swatch with 2 0.5 1.0 1.0 0.5 0.8 0.3
.mu.L 0.08% isovaleric acid 2 Stripped swatch with 5 2.0 2.0 2.0
2.0 2.0 0 .mu.L 0.08% isovaleric acid 3 Stripped swatch with 20 3.0
3.0 3.0 2.5 2.9 0.2 .mu.L 0.08% isovaleric acid
[0141] The reference swatches represent the 0, 1, 2, and 3 BIs on
the BI reference scale, Table 12. The expert grader should
familiarizes him/herself with the strength of the odor on the BI
reference swatches by sniffing each one starting at 0 (the lowest
odor strength) and ending at 3 (the highest odor strength). This
should be done prior to evaluating the swatch treated with the test
material.
TABLE-US-00014 TABLE 12 Swatch treatments comprising the Blocker
Index (BI) reference scale. Swatch/treatment Wt of isovaleric acid
BI Clean fabric swatch w/20 .mu.L 16 mg isovaleric acid 3 0.08%
isovaleric acid Clean fabric swatch w/5 .mu.L 4 mg isovaleric acid
2 0.08% isovaleric acid Clean fabric swatch w/2 .mu.L 1.6 mg
isovaleric acid 1 0.08% isovaleric acid Clean fabric swatch NIL
isovaleric acid NIL isovaleric acid 0
Making the Malodorous Swatch and Treating it with a Test
Material
[0142] To evaluate the BI, the test material is applied to a
malodorous swatch to determine how well the test material blocks
the malodor. The malodorous swatch is made by treating a clean
swatch with 20 .mu.L of a 0.08% solution of isovaleric acid. Dry
the malodorous swatch treated with isovaleric acid in a vented hood
for 30 minutes. After drying the malodorous swatch a known
concentration of test material solution, between 1 ppm and 100 ppm
is pipetted onto the malodorous swatch. Apply the test material
solution right on top of the spot where the isovaleric acid
solution was applied making an about 1 cm diameter spot. Just like
the BI reference swatches, the isovaleric acid+test material swatch
is dried in a vented hood for 30 minutes and then wrapped in
aluminum foil to prevent contamination. The isovaleric acid+test
material swatches and the BI reference swatches should be made
within 2 hrs of each other. The isovaleric acid+test material
swatch must be used between 1-12 hours just like the reference
swatches. It is sometimes necessary to evaluate several levels of
the test material between about 1 and about 100 ppm to determine
the BI.
Assigning the BI to the Test Material
[0143] At least two perfumers/expert graders are used to assign the
BI to the test sample. The expert grader smells the isovaleric
acid+test material swatch by holding that swatch one inch from
their nose with their nose centered over the area where the test
sample was pipetted on to the fabric and then assigns the
isovaleric acid+test material swatch a BI based on ranking its odor
strength against the odor strength of the swatches in the BI
reference scale. The test sample swatch is assigned a BI at or
between numbers on the BI in table. In cases where the isovaleric
acid+test material swatch odor is greater than 3 on the BI
reference scale, this indicates the material is not a blocker or
the concentration of the test material needs to be lowered to
achieve its blocker functionality.
Malodor Reduction Compounds with FFI and BI Grades Based on the
Aforementioned
TABLE-US-00015 Table Ref # CAS# log P Name Conc FFI BI 281
54830-99-8 3.11 3a,4,5,6,7,7a-hexahydro-4,7- 10 ppm 0 2.0
methano-1H-indenyl acetate 50 ppm 0.5 2.0 677 139504-68-0 3.75
1-((2-(tert- 10 ppm 0 2.3 butyl)cyclohexyl)oxy)butan-2-ol 50 ppm
1.8 2.0 962 55066-48-3 3.17 3-methyl-5-phenylpentan-1-ol 10 ppm 0
2.3 50 ppm 0.5 1.7 261 173445-65-3 3.29
3-(3,3-dimethyl-2,3-dihydro-1H- 10 ppm 0 1.8 inden-5-yl)propanal 50
ppm 1.3 1.3 1139 87731-18-8 2.11 (Z)-cyclooct-4-en-1-yl methyl 10
ppm 0 2.0 carbonate 50 ppm 1.0 2.7 4430-31-3 1.43
3,4,4a,5,6,7,8,8a-octahydrochromen- 10 ppm 0 2.0 2-one 50 ppm 0 2.0
204 40379-24-6 3.89 7-methyloctyl acetate 10 ppm 0 2.0 50 ppm 0 2.7
1005 93981-50-1 5.59 ethyl (2,3,6-trimethylcyclohexyl) 50 ppm 0.5
2.6 carbonate 391 106-33-2 5.73 Ethyl laurate 50 ppm 0.3 2.2 1148
1139-30-6 4.06 Caryophyllene Oxide 50 ppm 0.5 2.3 524 13877-91-3
4.31 3,7-Dimethyl-1,3,6-Octatriene(cis-.beta. 50 ppm 0 2.8
3338-55-4 ocimene 70%) 1149 23787-90-8 4
1,3,4,6,7,8alpha-hexahydro- 10 ppm 0 1.5
1,1,5,5-tetramethyl-2H-2,4alpha- 50 ppm 0.8 2.3
methanophtalen-8(5H)-one 112-42-5 4.62 Undecanol 50 ppm 0.8 2.3 174
112-53-8 5.17 1-dodecanol 50 ppm 0.5 2.3 98-52-2 2.78 4-tert-butyl
cyclohexane 10 ppm 0 2.0 50 ppm 0.3 2.0 109 112-39-0 6.41 Methyl
palmitate 10 ppm 2.0
Malodor Control Compounds with Improved Performance at Lower
Levels.
[0144] Below are some non-limiting examples of preferred behavior
by which the malodor control compound gives improved malodor
control at lower concentration. These nonlimiting data provide
additional compelling data that malodor is being blocked, not
masked.
TABLE-US-00016 Table Ref # CAS# Name Conc FFI BI N/A 68912-13-0
8,8-dimethyl-3a,4,5,6,7,7a- 10 ppm 0 1.5 hexahydro-1H-4,7- 50 ppm 0
2.2 methanoinden- 6-yl propionate N/A NA
4,8-dimethyl-1-(methylethyl)- 10 ppm 2.0 7-oxybiciclo [4.3.0]nonane
50 ppm 0.3 2.2
Retesting Malodor Reduction Compounds at Lower Levels.
[0145] The example below demonstrates that while a malodor control
compound could fail to demonstrate odor blocking (BI>2.5) at a
higher concentration it should be retested at a lower concentration
to determine if it passes.
TABLE-US-00017 Table Ref # CAS # Name Conc FFI BI N/A 173445-65-3
1H-Indene-5-propanal, 10 ppm 0 1.5 2,3-dihydro-3,3-dimethyl- 50 ppm
0.5 2.7
Example 1 Compositions Comprising Malodor Reduction Compounds
[0146] In the present invention blends enable more potent malodor
reduction because blends are useful at a higher % of the product
composition before becoming olfactively noticeable. Below are
non-limiting examples of malodor reduction compounds.
TABLE-US-00018 % wt Active Component CAS# A B C D E
2,2,8,8-tetramethyl-octahydro-1H- 29461-14-1 35-45 15-25 5-20 10-30
15-25 2,4a-methanonapthalene-10-one 1H-Indene-ar-propanal,2,3-
300371-33-9 10-20 1-30 NIL 5-10 1-5 dihydro-1,1-dimethyl-
Hexadecanoic acid, (2E)-3,7- 3681-73-0 35-45 10-25 NIL 30-40 35-50
dimethyl-2,6-octadien-1-yl ester 1-Pentanol-3-methyl-5-phenyl
55066-48-3 10-20 10-25 2-10 5-17 10 4,7-Methano-1H-inden-5-ol,
171102-41-3 0-5 10-25 NIL 1-6 1-5 3a,4,5,6,7,7a-hexahydro-,
5-acetate 4,8-dimethyl-1-(methylethyl)-7- N/A 0-5 NIL NIL NIL 1-5
oxybiciclo [4.3.0]nonane (3Z)-3,7-dimethylocta-1,3,6-triene
3338-55-4 NIL NIL 10-20 2-5 NIL 1H-Indene-5-propanal, 2,3-
173445-65-3 NIL NIL NIL 7.5-16 1-15 dihydro-3,3-dimethyl-
3,4,4a,5,6,7,8,8a- 4430-31-3 NIL NIL NIL 3-7 1-15
octahydrochromen-2-one 1-(2-tert- 139504-68-0 NIL NIL NIL 0.25-1.5
NIL butylcyclohexyl)oxybutan-2-ol ethyl (2,3,6-trimethylcyclohexyl)
93981-50-1 NIL NIL 15-30 NIL 2 carbonate benzyl 2-hydroxypropanoate
2051-96-9 NIL NIL 2-5 NIL NIL (3,5-dimethylcyclohex-3-en-1-
67634-16-6 NIL NIL 5-30 NIL NIL yl)methanol 2-Dodecanol 10203-28-8
NIL 0.25-1 NIL 0.5-3.sup. NIL
Example 2 Compositions Comprising Malodor Reduction Compounds
TABLE-US-00019 [0147] % wt Active Ingredient CAS # A B C B D E
(E)-1-(2,6,6-trimethyl-1- 127-42-4 4 8 2 8 3 2
cyclohex-2-enyl)pent-1-en-3- one ethyl dodecanoate 106-33-2 NIL 1
NIL 3 NIL NIL 3a,4,5,6,7,7a-hexahydro-1H- 68912-13-0 8 30 1 4 1 3.5
4,7-methanoind3en-1-yl propanoate [1R-(1R*,4R*,6R*,10S*)]-
1139-30-6 NIL 0.3 2 0.5 NIL 0.5 4,12,12-trimethyl-9- methylene-5-
oxatricyclo[8.2.0.04,6]dodecane (8E)-cyclohexadec-8-en-1-one
3100-36-5 NIL 5 NIL 7 NIL NIL 3,5,5-trimethylhexyl acetate
58430-94-7 25 15 50 35 60 56 ethyl (2,3,6- 93981-50-1 NIL 1 NIL 5
NIL NIL trimethylcyclohexyl) carbonate 2,4-dimethyl-4,4a,5,9b-
27606-09-3 25 10 15 15 16 15 tetrahydroindeno[1,2- d][1,3]dioxine
2,2,7,7- 23787-90-8 8 9 5 7 5 5 tetramethyltricyclo[6.2.1.01,6]
undecan-5-one (3,5-dimethylcyclohex-3-en- 67634-16-6 NIL 0.7 NIL
0.5 NIL NIL 1-yl)methanol 3-(7,7-dimethyl-4- 33885-52-8 30 20 25 15
15 18 bicyclo[3.1.1]hept-3-enyl)- 2,2-dimethylpropanal Total 100
100 100 100 100 100
Example 3 Malodor Reduction Composition
TABLE-US-00020 [0148] % wt Active Ingredient CAS # A B C
5-Cyclohexadecen-1-One 37609-25-9 15.0 2.00 2.00
decahydro-2,2,7,7,8,9,9- 476332-65-7 0.005 0.01 0.01
heptamethylindeno(4,3a-b)furan 2,3-Dihydro-5,6-dimethoxy-2-(4-
33704-61-9 0.3 0.5 0.5 piperidinylmethylene)-1H-inden-1-one Cedryl
Methyl Ether 19870-74-7 6.0 10.0 4.0 Trans-4-Decenal 65405-70-1
0.005 0.002 0.002 Decyl Aldehyde 112-31-2 3.74 2.0 2.0 3-methyl
cyclopentadecenone 63314-79-4 0.4 1.0 1.0 Diphenyl Oxide 101-84-8
0.5 1.0 1.0 3a,4,5,6,7,7a-hexahydro-4,7-methano- 54830-99-8 5.0 8.0
8.0 1H-indenyl acetate 3a,4,5,6,7,7a-hexahydro-1H-4,7- 68912-13-0
6.0 8.0 8.0 methanoinden-1-yl propanoate
2-(5-methyl-2-propan-2-yl-8- 68901-32-6 10.0 15.0 15.0
bicyclo[2.2.2]oct-5-enyl)-1,3-dioxolane (E)-3,7-dimethyl-2,6-
3681-73-0 10.0 10.0 16.0 octadienylhexadecanoate Iso Nonyl Acetate
58430-94-7 6.65 8.0 3.0 2,2,7,7- 23787-90-8 10.0 8.0 8.0
tetramethyltricyclo[6.2.1.01,6]undecan-5- one (1-Methyl-2-(1,2,2-
198404-98-7 0.1 0.3 0.3 trimethylbicyclo[3.1.0]-hex-3-
ylmethyl)cyclopropyl)methanol Lauric Aldehyde 112-54-9 0.625 1.0
0.7 Methyl Iso Eugenol 93-16-3 18.000 10.0 13.0 Methyl
hexadecanoate 112-39-0 3.000 10.0 12.0
2,3-dihydro-1,1-1H-dimethyl-indene-ar- 300371-33-9 0.400 0.0 0.3
propanal 4-tert-butylcyclohexanol 98-52-2 0.400 0.1 0.1
2-isobutyl-4-hydroxy-4- 63500-71-0 1.600 2.0 2.0
methyltetrahydropyran Undecyl Aldehyde 112-44-7 1.725 2.888 1.888
Undecylenic Aldehyde 112-45-8 0.550 0.2 1.2 Total 100 100.0
100.0
Example 4 84 wt % Core/16 wt % Wall Melamine Formaldehyde (MF)
Capsule
[0149] 25 grams of butyl acrylate-acrylic acid copolymer emulsifier
(Colloid C351, 25% solids, pKa 4.5-4.7, (Kemira Chemicals, Inc.
Kennesaw, Ga. U.S.A.) is dissolved and mixed in 200 grams deionized
water. The pH of the solution is adjusted to pH of 4.0 with sodium
hydroxide solution. 8 grams of partially methylated methylol
melamine resin (Cymel 385, 80% solids, (Cytec Industries West
Paterson, N.J., U.S.A.)) is added to the emulsifier solution. 200
grams of perfume oil according to Table 1 or Table 2 is added to
the previous mixture under mechanical agitation and the temperature
is raised to 50.degree. C. After mixing at higher speed until a
stable emulsion is obtained, the second solution and 4 grams of
sodium sulfate salt are added to the emulsion. This second solution
contains 10 grams of butyl acrylate-acrylic acid copolymer
emulsifier (Colloid C351, 25% solids, pKa 4.5-4.7, Kemira), 120
grams of distilled water, sodium hydroxide solution to adjust pH to
4.8, 25 grams of partially methylated methylol melamine resin
(Cymel 385, 80% solids, Cytec). This mixture is heated to
70.degree. C. and maintained overnight with continuous stirring to
complete the encapsulation process. 23 grams of acetoacetamide
(Sigma-Aldrich, Saint Louis, Mo., U.S.A.) is added to the
suspension. An average capsule size of 30 um is obtained as
analyzed by a Model 780 Accusizer.
Example 5
[0150] To demonstrate the benefit of the present invention,
Applicants prepared liquid detergent matrix A, below.
TABLE-US-00021 Active Material in weight % A C.sub.14-C.sub.15
alkyl poly ethoxylate 7 3.39 C.sub.12-C.sub.14 alkyl poly
ethoxylate 7 1.13 C.sub.12-C.sub.14 alkyl poly ethoxylate 7.66 3
sulfate Na salt Alkylbenzene sulfonic acid 1.17 Citric Acid 2.73
C.sub.12-18 fatty acid 5.06 Enzymes 0.2 Boric Acid 1.40
Trans-sulphated ethoxylated 0.81 hexamethylene diamine quat
Diethylene triamine penta 0.12 methylene phosphonic acid
Hydrogenated Castor Oil structurant 0.300 Ethanol 1.59 1,2
propanediol 0.07 Sodium hydroxide 3.48 Silicone PDMS emulsion
0.0025 Blue Dye 0.0006 Preservative Acticide MBS 2550 (ex Thor)
0.0135 Perfume (Neat) 0.3 Malodor reducing composition (Neat) 0.02
Perfume/Malodor reducing 0 composition in delivery system Malodor
reducing composition in Delivery System 0.04 Merquat 5300 polymer
(1) 0.19 Water Balance to 100% (1) Merquat 5300: terpolymer with
mole ratio: 90% PAM/5% AA/5% MAPTAC produced by Nalco.
Examples 6-13 Laundry Detergent Compositions Comprising the Perfume
Composition are Included Below
TABLE-US-00022 [0151] % w/w of laundry detergent compositions
Material 6 7 8 9 10 11 12 13 Linear alkyl benzene 7.1 6.7 11.0 10.6
6.9 4.5 10.1 8.9 sulphonate Sodium C.sub.12-15 alkyl ethoxy 3.5 0.0
1.5 0.0 0.0 0.0 0.0 1.9 sulphate having a molar average degree of
ethoxylation of 3 Acrylic Acid/Maleic Acid 3.6 1.8 4.9 2.0 1.0 1.6
3.9 2.3 Copolymer Sodium Alumino Silicate 4.0 0.5 0.8 1.4 16.3 0.0
17.9 2.4 (Zeolite 4A) Sodium Tripolyphosphate 0.0 17.5 0.0 15.8 0.0
23.3 0.0 0.0 Sodium Carbonate 23.2 16.8 30.2 17.3 18.4 9.0 20.8
30.0 Sodium Sulphate 31.4 29.4 35.5 7.2 26.3 42.8 33.2 28.3 Sodium
Silicate 0.0 4.4 0.0 4.5 0.0 6.1 0.0 4.6 C.sub.14-15 alkyl
ethoxylated 0.4 2.6 0.8 2.5 3.1 0.3 3.8 0.4 alcohol having a molar
average degree of ethoxylation of 7 Sodium Percarbonate 16.0 0.0
8.4 20.4 13.1 3.6 0.0 7.0 Sodium Perborate 0.0 9.9 0.0 0.0 0.0 0.0
0.0 0.0 Tetraacetylethylenediamine 2.2 1.7 0.0 4.7 3.6 0.0 0.0 0.8
(TAED) Calcium Bentonite 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.6 Citric
acid 2.0 1.5 2.0 2.0 2.5 1.0 2.5 1.0 Protease (84 mg active/g) 0.14
0.12 0.0 0.12 0.09 0.08 0.10 0.08 Amylase (22 mg active/g) 0.10
0.11 0.0 0.10 0.10 0.0 0.14 0.08 Lipase (11 mg active/g) 0.70 0.50
0.0 0.70 0.50 0.0 0.0 0.0 Cellulase (2.3 mg active/g) 0.0 0.0 0.0
0.0 0.0 0.0 0.18 0.0 Free (Neat) Perfume 0.36 0.16 0.15 0.2 0.3 0.1
0.34 0.34 Free (Neat) malodor 0.04 0 0.03 .02 0 0 0.03 0.015
reducing composition Perfume/malodor reducing 0.14 0.5 0 0.25 0 0.2
0.25 0.5 composition encapsulated.sup.5 Malodor reducing 0 0 0.2 0
0.02 0 0 0 composition encapsulated.sup.5 Water & Miscellaneous
Balance to 100%
Examples 14-21 Granular Laundry Detergent Compositions Comprising
the Perfume Composition are Included Below
TABLE-US-00023 [0152] % w/w of laundry detergent compositions
Material 14 15 16 17 18 19 20 21 Linear alkyl benzene 7.1 6.7 11.0
10.6 6.9 4.5 10.1 8.9 sulphonate Sodium C.sub.12-15 alkyl ethoxy
3.5 0.0 1.5 0.0 0.0 0.0 0.0 1.9 sulphate having a molar average
degree of ethoxylation of 3 Acrylic Acid/Maleic Acid 3.6 1.8 4.9
2.0 1.0 1.6 3.9 2.3 Copolymer Sodium Alumino Silicate 4.0 0.5 0.8
1.4 16.3 0.0 17.9 2.4 (Zeolite 4A) Sodium Tripolyphosphate 0.0 17.5
0.0 15.8 0.0 23.3 0.0 0.0 Sodium Carbonate 23.2 16.8 30.2 17.3 18.4
9.0 20.8 30.0 Sodium Sulphate 31.4 29.4 35.5 7.2 26.3 42.8 33.2
28.3 Sodium Silicate 0.0 4.4 0.0 4.5 0.0 6.1 0.0 4.6 C.sub.14-15
alkyl ethoxylated 0.4 2.6 0.8 2.5 3.1 0.3 3.8 0.4 alcohol having a
molar average degree of ethoxylation of 7 Sodium Percarbonate 16.0
0.0 8.4 20.4 13.1 3.6 0.0 7.0 Sodium Perborate 0.0 9.9 0.0 0.0 0.0
0.0 0.0 0.0 Tetraacetylethylenediamine 2.2 1.7 0.0 4.7 3.6 0.0 0.0
0.8 (TAED) Calcium Bentonite 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.6 Citric
acid 2.0 1.5 2.0 2.0 2.5 1.0 2.5 1.0 Protease (84 mg active/g) 0.14
0.12 0.0 0.12 0.09 0.08 0.10 0.08 Amylase (22 mg active/g) 0.10
0.11 0.0 0.10 0.10 0.0 0.14 0.08 Lipase (11 mg active/g) 0.70 0.50
0.0 0.70 0.50 0.0 0.0 0.0 Cellulase (2.3 mg active/g) 0.0 0.0 0.0
0.0 0.0 0.0 0.18 0.0 Free (Neat) Perfume 0.36 0.16 0.15 0.2 0.3 0.1
0.34 0.34 Free (Neat) malodor 0.04 0 0.03 .02 0 0 0.03 0.015
reducing composition Perfume/malodor reducing 0.14 0.5 0 0.25 0 0.2
0.25 0.5 composition encapsulated.sup.5 Malodor reducing 0 0 0.2 0
0.02 0 0 0 composition encapsulated.sup.5 Water & Miscellaneous
Balance to 100%
[0153] The equipment and materials described in Examples 4 through
to 21 can be obtained from the following: IKA Werke GmbH & Co.
KG, Staufen, Germany; CP Kelco, Atlanta, United States; Forberg
International AS, Larvik, Norway; Degussa GmbH, Dusseldorf,
Germany; Niro A/S, Soeberg, Denmark; Baker Perkins Ltd,
Peterborough, United Kingdom; Nippon Shokubai, Tokyo, Japan; BASF,
Ludwigshafen, Germany; Braun, Kronberg, Germany; Industrial
Chemicals Limited, Thurrock, United Kingdom; Primex ehf,
Siglufjordur, Iceland; ISP World Headquarters; Polysciences, Inc.
of Warrington, Pa., United States; Cytec Industries Inc., New
Jersey, United States; International Specialty Products, Wayne,
N.J., United States; P&G Chemicals Americas, Cincinnati, Ohio,
United States; Sigma-Aldrich Corp., St. Louis, Mo., United States,
Dow Chemical Company of Midland, Mich., USA
Examples 22-31 Fabric Conditioner
[0154] Non-limiting examples of fabric conditioners containing the
polymer coated perfume microcapsules disclosed in the present
specification are summarized in the following table.
TABLE-US-00024 EXAMPLES (% wt) 22 23 24 25 26 27 28 29 30 31 FSA
.sup.a 14 16.47 14 12 12 16.47 -- -- 5 10 FSA .sup.b -- 3.00 -- --
-- FSA .sup.c -- -- 6.5 -- -- Ethanol 2.18 2.57 2.18 1.95 1.95 2.57
-- -- 0.81 Isopropyl -- -- -- -- -- -- 0.33 1.22 -- 1.0-- Alcohol
Starch .sup.d 1.25 1.47 2.00 1.25 -- 2.30 0.5 0.70 0.71 0.42 Phase
0.21 0.25 0.21 0.21 0.14 0.18 0.15 0.14 0.2 0.1 Stabilizing Polymer
.sup.f Suds Suppressor .sup.g -- -- -- -- -- -- -- 0.1 -- --
Calcium Chloride 0.15 0.176 0.15 0.15 0.30 0.176 -- 0.1-0.15 --
0025. DTPA .sup.h 0.017 0.017 0.017 0.017 0.007 0.007 0.20 -- 0.002
0.002 Preservative 5 5 5 5 5 5 -- 250 .sup.j 5 5 (ppm) .sup.i, j
Antifoam.sup.k 0.015 0.018 0.015 0.015 0.015 0.015 -- -- 0.015
0.015 Dye (ppm) 40 40 40 40 40 40 11 30-300 30 30 Ammonium 0.100
0.118 0.100 0.100 0.115 0.115 -- -- -- -- Chloride HCl 0.012 0.014
0.012 0.012 0.028 0.028 0.016 0.025 0.011 0.011 Perfume 0.2 0.02
0.1 0.15 0.12 0.13 0.3 0.4 0.24 0.1 microcapsules as disclosed in
Example 1 Malodor 0 0 0.2 0 0.02 0 0 0 0.5 0.02 reducing
composition encapsulated.sup.5 Perfume/ 0.14 0.5 0 0.25 0 0.2 0.25
0.5 0 0 malodor reducing composition encapsulated.sup.5 Additional
Neat 0.8 0.7 0.9 0.5 1.2 0.5 1.1 0.6 1.0 0.9 Perfume Free (Neat)
0.04 0 0.03 0.02 0 0 0.03 0.015 0.03 0.02 malodor reducing
composition Deionized .dagger. .dagger. .dagger. .dagger. .dagger.
.dagger. .dagger. .dagger. .dagger. .dagger. Water .sup.a
N,N-di(tallowoyloxyethyl)-N,N-dimethylammonium chloride. .sup.b
Methyl bis(tallow amidoethyl)2-hydroxyethyl ammonium methyl
sulfate. .sup.c Reaction product of Fatty acid with
Methyldiethanolamine in a molar ratio 1.5:1, quaternized with
Methylchloride, resulting in a 1:1 molar mixture of
N,N-bis(stearoyl-oxy-ethyl) N,N-dimethyl ammonium chloride and
N-(stearoyl-oxy-ethyl) N,-hydroxyethyl N,N dimethyl ammonium
chloride. .sup.d Cationic high amylose maize starch available from
National Starch under the trade name CATO .RTM.. .sup.f Rheovis DCE
ex BASF. .sup.g SE39 from Wacker .sup.h
Diethylenetriaminepentaacetic acid. .sup.i KATHON .RTM. CG
available from Rohm and Haas Co. "PPM" is "parts per million."
.sup.j Gluteraldehyde .sup.kSilicone antifoam agent available from
Dow Corning Corp. under the trade name DC2310. .dagger. balance
Examples 32-37 Liquid Laundry Formulations (HDLs)
TABLE-US-00025 [0155] Ingredient 32 33 34 35 36 37 Alkyl Ether
Sulphate 0.00 0.50 12.0 12.0 6.0 7.0 Dodecyl Benzene 8.0 8.0 1.0
1.0 2.0 3.0 Sulphonic Acid Ethoxylated Alcohol 8.0 6.0 5.0 7.0 5.0
3.0 Citric Acid 5.0 3.0 3.0 5.0 2.0 3.0 Fatty Acid 3.0 5.0 5.0 3.0
6.0 5.0 Ethoxysulfated 1.9 1.2 1.5 2.0 1.0 1.0 hexamethylene
diamine quaternized Diethylene triamine penta 0.3 0.2 0.2 0.3 0.1
0.2 methylene phosphonic acid Enzymes 1.20 0.80 0 1.2 0 0.8
Brightener (disulphonated 0.14 0.09 0 0.14 0.01 0.09 diamino
stilbene based FWA) Cationic hydroxyethyl 0 0 0.10 0 0.200 0.30
cellulose Poly(acrylamide-co- 0 0 0 0.50 0.10 0
diallyldimethylammonium chloride) Hydrogenated Castor Oil 0.50 0.44
0.2 0.2 0.3 0.3 Structurant Boric acid 2.4 1.5 1.0 2.4 1.0 1.5
Ethanol 0.50 1.0 2.0 2.0 1.0 1.0 1,2 propanediol 2.0 3.0 1.0 1.0
0.01 0.01 Glutaraldehyde 0 0 19 ppm 0 13 ppm 0 Diethyleneglycol
(DEG) 1.6 0 0 0 0 0 2,3-Methyl-1,3- 1.0 1.0 0 0 0 0 propanediol (M
pdiol) Mono Ethanol Amine 1.0 0.5 0 0 0 0 NaOH Sufficient To pH 8
pH 8 pH 8 pH 8 pH 8 pH 8 Provide Formulation pH of: Sodium Cumene
2.00 0 0 0 0 0 Sulphonate (NaCS) Silicone (PDMS) emulsion 0.003
0.003 0.003 0.003 0.003 0.003 Perfume (neat) 0.2 0.15 0 0.2 0.2 0.1
Malodor reducing 0.01 0.002 0.08 0 0 0.001 composition (neat)
Malodor reducing 0.1 0.1 0 0.2 0 0 composition in delivery system
Perfume/Malodor reducing 0 0 0.22 0 0.3 0.2 composition in delivery
system Water Balance Balance Balance Balance Balance Balance
Examples 38-45: Liquid Unit Dose
[0156] The following are examples of unit dose executions wherein
the liquid composition is enclosed within a PVA film. The preferred
film used in the present examples is Monosol M8630 76 .mu.m
thickness.
TABLE-US-00026 D E F 3 compartments 2 compartments 3 compartments
Compartment # 38 39 40 41 42 43 44 45 Dosage (g) 34.0 3.5 3.5 30.0
5.0 25.0 1.5 4.0 Ingredients Weight % Alkylbenzene sulfonic 20.0
20.0 20.0 10.0 20.0 20.0 25 30 acid Alkyl sulfate 2.0 C.sub.12-14
alkyl 7- 17.0 17.0 17.0 17.0 17.0 15 10 ethoxylate C.sub.12-14
alkyl ethoxy 3 7.5 7.5 7.5 7.5 7.5 sulfate Citric acid 0.5 2.0 1.0
2.0 Zeolite A 10.0 C.sub.12-18 Fatty acid 13.0 13.0 13.0 18.0 18.0
10 15 Sodium citrate 4.0 2.5 enzymes 0-3 0-3 0-3 0-3 0-3 0-3 0-3
Sodium Percarbonate 11.0 TAED 4.0 Polycarboxylate 1.0 Ethoxylated
2.2 2.2 2.2 Polyethylenimine.sup.1 Hydroxyethane 0.6 0.6 0.6 0.5
2.2 diphosphonic acid Ethylene diamine 0.4 tetra(methylene
phosphonic) acid Brightener 0.2 0.2 0.2 0.3 0.3 Perfume/Malodor 0.4
0 1.5 1.3 0 0 0.12 0 reducing composition in delivery system
Malodor reducing 0 0.25 0 0 0.10 0.25 0 0.12 composition in
delivery system Water 9 8.5 10 5 11 10 10 9 CaCl2 0.01 Perfume
(neat) 1.7 1.7 0.6 0.2 1.5 0.5 0.1 Malodor reducing 0.015 0.002
0.02 0.06 0 0 0.002 0 composition (neat) Minors (antioxidant, 2.0
2.0 2.0 4.0 1.5 2.2 2.2 2.0 sulfite, aesthetics, . . .) Buffers
(sodium To pH 8.0 for liquids carbonate, To RA > 5.0 for powders
monoethanolamine) .sup.3 Solvents (1,2 To 100 p propanediol,
ethanol), Sulfate Polyethylenimine (MW = 600) with 20 ethoxylate
groups per --NH. .sup.3 RA = Reserve Alkalinity (g NaOH/dose)
Example 46-47 Shampoo Formulation
TABLE-US-00027 [0157] Ingredient 46 47 Ammonium Laureth Sulfate
(AE.sub.3S) 6.00 6.00 Ammonium Lauryl Sulfate (ALS) 10.00 10.00
Laureth-4 Alcohol 0.90 0.90 Trihydroxystearin 0.10 0.10 Perfume
(neat) 0.15 0.15 Malodor reducing composition (neat) 0 0
Perfume/malodor delivery in 0.4 0.2 delivery system Malodor
reducing composition in 0 0.05 delivery system Sodium Chloride 0.40
0.40 Citric Acid 0.04 0.04 Sodium Citrate 0.40 0.40 Sodium Benzoate
0.25 0.25 Ethylene Diamine Tetra Acetic Acid 0.10 0.10 Dimethicone
1.00 1.00 Water and Minors (QS to 100%) Balance Balance
Example 48-55: Free Flowing Particles Products
[0158] Free flowing particles products that comprise perfume and/or
microcapsules comprising such perfume are provided below. The table
below also exemplifies combinations which comprise also perfume
free and in microcapsules or combinations of these with
aforementioned combinations with malodor reduction materials and/or
compositions. The table also exemplifies compositions having only
malodor reduction materials and/or compositions free, in
microcapsules and combinations thereof that have little to no
fragrance to provide a product that is essentially `fragrance
free`
TABLE-US-00028 COMPOSITION 48 49 50 51 % Wt % Wt % Wt % Wt
Component Active Active Active Active Polyethylene 70-99 0-20 0-29
0-40 glycol Clay 0-29 0-20 0-20 0-10 NaCl 0-29 50-99 0-29 0-40
Na2SO4 0-10 0-10 0-10 0-5 Urea 0-29 0-29 0-99 0-40 Polysaccharide
0-29 0-29 0-29 0-5 Zeolite 0-29 0-29 0-29 0-5 Plasticizers/
Solvents Starch/Zeolite 0-29 0-29 0-29 0-5 Silica 0-5 0-5 0-5 0-5
Metal oxide 0-29 0-29 0-29 0-29 Metal catalyst 0.001-0.5 0.001-0.5
0.001-0.5 0.001-0.5 Opacifier 0-5 0-5 0-1 0-1 Water 0-2 0-2 0-5 0-5
Perfume 0-5 0-5 0-5 0-5 Delivery 0.001-10 0.001-4.5 0.001-3
0.001-7.5 System comprising malodor reduction composition
COMPOSITION 52 53 54 55 % Wt % Wt % Wt % Wt Component Active Active
Active Active Polyethylene 70-99 0-20 0-29 0-40 glycol Clay 0-29
0-20 0-20 0-10 NaCl 0-29 50-99 0-29 0-40 Na2SO4 0-10 0-10 0-10 0-5
Urea 0-29 0-29 0-99 0-40 Polysaccharide 0-29 0-29 0-29 0-5 Zeolite
0-29 0-29 0-29 0-5 Plasticizers/ Solvents Starch/Zeolite 0-29 0-29
0-29 0-5 Silica 0-5 0-5 0-5 0-5 Metal oxide 0-29 0-29 0-29 0-29
Metal catalyst 0.001-0.5 0.001-0.5 0.001-0.5 0.001-0.5 Opacifier
0-5 0-5 0-1 0-1 Water 0-2 0-2 0-5 0-5 Delivery 0.001-10 0.001-4.5
0.001-3 0.001-7.5 System comprising perfume/ malodor reducing
composition (1) PEG (2) Clay (3) Urea (4) Polysaccharide, mostly
starches, unmodified starches, starch derivatives, acid-modified
starch and kappa carrageenan (5) Zeolite (6) Starch/Zeolite - SEA
(7) Metal oxides - non-limiting examples - TiO2, ZnO, MnO (8) Metal
catalysts (9) Opacifier
Example 56-60 Aqueous Composition/Fabric Refresher or Air
Freshening Composition
TABLE-US-00029 [0159] Ingredient 56 57 58 59 60 Deionized Water
Balance Balance Balance Balance Balance Ethanol 3.0 3.0 3.0 3.0 3.0
Lupasol HF.sup.1 0 0 0 0 0 Hydroxypropyl b-CD 0 0 0 0 0 Diethylene
Glycol 0 0 0 0 0 Silwet L-7600 0.1 0.1 0.1 0.100 0.100 Basophor
EL60.sup.2 0 0.05 0.05 0.05 0.05 Maleic Acid and/or As needed As
needed As needed As needed As needed Citric Acid.sup.3 Koralone
B-119 0.015 0.015 0.015 0.015 0.015 Hydroxypropyl .beta.- 0 0 0 0 0
cyclodextrin Sodium Hydroxide.sup.3 As needed As needed As needed
As needed As needed Malodor Reducing 0.03 0.05 0 0 .02 composition
Ex. 1-3 Delivery System 0 0.2 0 .03 comprising perfume/malodor
reducing composition Delivery System 0 0.05 0 0.05% 0 comprising
malodor reducing composition Perfume (neat) 0.04 0.01 0 0.05 0
Target pH 6.8 6.8 6.8 6.8 6.8 Total 100.000 100.000
[0160] The resulting fabric refreshing spray product when used to
treat fabric surfaces is effective at reducing malodor on the
treated fabric.
[0161] The dimensions and values disclosed herein are not to be
understood as being strictly limited to the exact numerical values
recited. Instead, unless otherwise specified, each such dimension
is intended to mean both the recited value and a functionally
equivalent range surrounding that value. For example, a dimension
disclosed as "40 mm" is intended to mean "about 40 mm."
[0162] Every document cited herein, including any cross referenced
or related patent or application and any patent application or
patent to which this application claims priority or benefit
thereof, is hereby incorporated herein by reference in its entirety
unless expressly excluded or otherwise limited. The citation of any
document is not an admission that it is prior art with respect to
any invention disclosed or claimed herein or that it alone, or in
any combination with any other reference or references, teaches,
suggests or discloses any such invention. Further, to the extent
that any meaning or definition of a term in this document conflicts
with any meaning or definition of the same term in a document
incorporated by reference, the meaning or definition assigned to
that term in this document shall govern.
[0163] While particular embodiments of the present invention have
been illustrated and described, it would be obvious to those
skilled in the art that various other changes and modifications can
be made without departing from the spirit and scope of the
invention. It is therefore intended to cover in the appended claims
all such changes and modifications that are within the scope of
this invention.
* * * * *
References