U.S. patent application number 14/950503 was filed with the patent office on 2017-02-09 for process for the separation and purification of a mixed diol stream.
This patent application is currently assigned to Eastman Chemical Company. The applicant listed for this patent is Eastman Chemical Company. Invention is credited to Scott Donald Barnicki.
Application Number | 20170036976 14/950503 |
Document ID | / |
Family ID | 46491268 |
Filed Date | 2017-02-09 |
United States Patent
Application |
20170036976 |
Kind Code |
A9 |
Barnicki; Scott Donald |
February 9, 2017 |
PROCESS FOR THE SEPARATION AND PURIFICATION OF A MIXED DIOL
STREAM
Abstract
Disclosed is a process for the purification of a mixed diol
stream. The mixed diol stream comprising two-, three-, and
four-carbon diols is separated into component diols by extraction
with a hydrophobic solvent mixture. The diols recovered in the
extractant may be removed from the extractant stream by back
extraction with water or by distillation with an azeotrope-forming
agent present, preferably an azeotroping agent already present in
the extractant mixture.
Inventors: |
Barnicki; Scott Donald;
(Kingsport, TN) |
|
Applicant: |
Name |
City |
State |
Country |
Type |
Eastman Chemical Company |
Kingsport |
TN |
US |
|
|
Assignee: |
Eastman Chemical Company
Kingsport
TN
|
Prior
Publication: |
|
Document Identifier |
Publication Date |
|
US 20160075622 A1 |
March 17, 2016 |
|
|
Family ID: |
46491268 |
Appl. No.: |
14/950503 |
Filed: |
November 24, 2015 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
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13431308 |
Mar 27, 2012 |
9227896 |
|
|
14950503 |
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12889065 |
Sep 23, 2010 |
8466328 |
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13431308 |
|
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61374850 |
Aug 18, 2010 |
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Current U.S.
Class: |
1/1 |
Current CPC
Class: |
C07C 29/86 20130101;
C07C 29/86 20130101; C07C 29/86 20130101; Y02P 20/52 20151101; C07C
29/149 20130101; C07C 29/86 20130101; C07C 29/80 20130101; C07C
31/205 20130101; B01J 31/2409 20130101; C07C 31/202 20130101; C07C
31/207 20130101; B01J 2531/821 20130101; B01J 2531/0258
20130101 |
International
Class: |
C07C 29/86 20060101
C07C029/86 |
Claims
1. A process for recovering diols from a mixed diol stream,
comprising (A) extracting said mixed diol stream, comprising (i)
0.1 weight percent to 50 weight percent of one or more diols
selected from the group consisting of ethylene glycol,
1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; (ii) 5 weight percent to 90
weight percent glycerol; and (iii) 5 weight percent to 90 weight
percent water; each based on the total weight of said mixed diol
steam stream, with an extractant, comprising (i) a hydrophobic
solvent selected from alkanols having from 6 to 20 carbon atoms,
ketones having from 5 to 20 carbon atoms, esters having from 5 to
20 carbon atoms, ethers having from 5 to 20 carbon atoms,
carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of said glycerol and a minor amount of said diols contained in said
mixed diol stream and an extract phase comprising a major amount of
said diols and a minor amount of said glycerol contained in said
mixed diol stream; and (B) separating said raffinate phase and said
extract phase.
2. The process according to claim 1 wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
3. The process according to claim 2 wherein greater than 99.5
weight percent of said glycerol is recovered in said raffinate
phase and greater than 90 weight percent of said diols is recovered
in said extract phase; and wherein said extraction occurs in a
continuous counter-current extractor, wherein said extractant is
fed lower to said extractor than said mixed diol stream, wherein
the feed ratio of said extractant to said mixed diol stream ranges
from 0.1:1 to 10:1; further comprising feeding a hydrophilic stream
to said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2.0:1, and wherein said
hydrophilic stream comprises water.
4. A process for recovering diols from a mixed diol stream,
comprising (A) extracting said mixed diol stream, comprising (i)
0.1 weight percent to 30 weight percent of one or more diols
selected from the group consisting of ethylene glycol,
1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; (ii) 5 weight percent to 50
weight percent glucose; and (iii) 50 weight percent to 90 weight
percent water; each based on the total weight of said mixed diol
steam stream, with an extractant, comprising (i) a hydrophobic
solvent selected from alkanols having from 6 to 20 carbon atoms,
ketones having from 5 to 20 carbon atoms, esters having from 5 to
20 carbon atoms, ethers having from 5 to 20 carbon atoms,
carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of said glycerol and a minor amount of said diols contained in said
mixed diol stream and an extract phase comprising a major amount of
said diols and a minor amount of said glycerol contained in said
mixed diol stream; and (B) separating said raffinate phase and said
extract phase.
5. The process according to claim 4 wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
6. The process according to claim 5 wherein greater than 99.5
weight percent of said glucose is recovered in said raffinate phase
and greater than 90 weight percent of diols is recovered in said
extract phase; and wherein said extraction occurs in a continuous
counter-current extractor, wherein said extractant is fed lower to
said extractor than said mixed diol stream, wherein the feed ratio
of said extractant to said mixed diol stream ranges from 0.1:1 to
10:1; further comprising feeding a hydrophilic stream to said
extractor at a higher level than said mixed diol stream, wherein
the feed ratio of said hydrophilic stream to said mixed diol stream
ranges from 0.05:1 to 2.0:1, and wherein said hydrophilic stream
comprises water.
7. A process for recovering purified three-carbon diols from a
mixed diol stream, comprising (A) extracting said mixed diol
stream, comprising (i) 1 weight percent to 99.5 weight of one or
more three-carbon diols selected from 1,2-propanediol and
1,3-propanediol; (ii) 20 ppm by weight to 99 weight percent of one
or more four-carbon diols selected from 1,2-butanediol,
1,3-butanediol, 1,4-butanediol, and 2,3-butanediol; each based on
the total weight of said diols, and (iii) 0 weight percent to 50
weight percent water, based on the total weight of said diols and
said water, with an extractant, comprising (i) a hydrophobic
solvent selected from alkanols having from 6 to 20 carbon atoms,
ketones having from 5 to 20 carbon atoms, esters having from 5 to
20 carbon atoms, ethers having from 5 to 20 carbon atoms,
carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of said three-carbon diols and a minor amount of said four-carbon
diols contained in said mixed diol stream and an extract phase
comprising a major amount of said four-carbon diols and a minor
amount of said three-carbon diols contained in said mixed diol
stream; and (B) separating said raffinate phase and said extract
phase.
8. The process according to claim 7 wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
9. The process according to claim 8 wherein greater than 99.5
weight percent of said three-carbon diols in said mixed diol stream
is recovered in said raffinate phase and greater than 90 weight
percent of said four-carbon diols is recovered in said extract
phase; and wherein said extraction occurs in a continuous
counter-current extractor, wherein said extractant is fed lower to
said extractor than said mixed diol stream, wherein the feed ratio
of said extractant to said mixed diol stream ranges from 0.1:1 to
10:1; further comprising feeding a hydrophilic stream to said
extractor at a higher level than said mixed diol stream, wherein
the feed ratio of said hydrophilic stream to said mixed diol stream
ranges from 0.05:1 to 1.5:1, and wherein said hydrophilic stream
comprises water.
Description
CROSS REFERENCES TO RELATED APPLICATIONS
[0001] This application is a Divisional of U.S. application Ser.
No. 13/431,308 filed Mar. 27, 2012 now United States Publication
Number 2012-0184783 which is a Continuation-In-Part of U.S.
application Ser. No. 12/889,065, filed Sep. 23, 2010 now U.S. Pat.
No. 8,466,328, which claims the benefit of U.S. Provisional
Application No. 61/374,850, filed Aug. 18, 2010, all of which are
incorporated herein by reference in their entireties.
FIELD OF THE INVENTION
[0002] This invention relates to a process for the purification of
a mixed diol stream. More specifically, this invention relates to
the separation of two-, three-, and four-carbon diols. One aspect
of this invention relates to a process for the purification of
ethylene glycol by the separation of propylene and butylene
glycols. Another aspect of this invention relates to the separation
of mixtures of propylene glycols from butylene glycols. Further,
this invention relates to a process wherein a mixed diol stream may
be separated by extraction or extraction and distillation
processes.
BACKGROUND OF THE INVENTION
[0003] Two-, three-, and four-carbon diols, as exemplified by
ethylene glycol, 1,2-propanediol, 1,3-propanediol, 1,2-butanediol,
2,3-butanediol, 1,3-butanediol, and 1,4-butanediol, find use in a
myriad of industrially important polymers and formulations. Many
processes have been disclosed for the production of these diols.
For example, ethylene glycol can be produced by the hydrogenation
of glycolic acid, glycolic acid esters, methyl glycolate, oligomers
of glycolic acid, oligomers of glycolic acid ester, or mixtures
thereof with a ruthenium compound such as, for example, a
ruthenium-organophophorus coordination compound, that is soluble or
partly soluble in the reaction mixture. Such a glycolic acid-based
route has been described in the art as disclosed in U.S. Pat. No.
7,615,671. The hydrogenation of glycolic acid species may also
produce by-product higher diols, primarily 1,2-propanediol and
1,2-butanediol, in small quantities, e.g., typically less than 1
weight percent of each compared to ethylene glycol.
[0004] Carbohydrate feedstocks also may be used to produce mixed
diol streams with varying amounts and particular species of
two-carbon diols, three-carbon diols, four-carbon-diols, and higher
diols.
[0005] It is desirable to separate the mixed diol stream into its
component diols in a most economic manner. Distillation, a common
method of separation, can prove difficult when components have
close boiling points. The normal boiling points of ethylene glycol,
1,2-propanediol, and 1,2-butanediol are 197.1.degree. C.,
187.7.degree. C., and 196.5.degree. C. respectively, and ethylene
glycol and 1,2-butanediol are known to form a minimum boiling
azeotrope, precluding complete separation by single-feed ordinary
fractional distillation. Separation of such mixed diol streams into
pure fractions by ordinary single-feed fractional distillation is
extremely difficult, if not impossible due to numerous azeotropes
and close boiling points.
[0006] There is a need for a process whereby a diol mixture can be
separated into pure fractions in an efficient and cost-effective
manner.
SUMMARY OF INVENTION
[0007] We have discovered that a mixed diol stream can be
efficiently separated into component fractions by extraction. One
embodiment of our invention, therefore, is a process for recovering
purified ethylene glycol from a mixed diol stream, comprising
[0008] (A) extracting the mixed diol stream, comprising [0009] (i)
1 weight percent to 99.5 weight percent, ethylene glycol; [0010]
(ii) 20 ppm by weight to 99 weight percent of one or more
three-carbon diols and four-carbon diols selected from
1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; each based on the total weight
of diols, and [0011] (iii) 0 weight percent to 50 weight percent
water, based on the total weight of diols and water, with an
extractant, comprising [0012] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0013] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the three-carbon diols and/or four-carbon diols contained
in the mixed diol stream and an extract phase comprising a major
amount of the three-carbon diols and/or four-carbon diols and a
minor amount of the ethylene glycol contained in the mixed diol
stream; and [0014] (B) separating the raffinate phase and the
extract phase.
[0015] A second embodiment of our invention is a process for
recovering purified ethylene glycol from a mixed diol stream,
comprising [0016] (A) extracting the mixed diol stream, comprising
[0017] (i) 20 weight percent to 99.5 weight percent, ethylene
glycol; [0018] (ii) 20 ppm by weight to 40 weight percent of one or
more three-carbon diols selected from 1,2-propanediol and
1,3-propanediol, and 20 ppm by weight to 30 weight percent of one
or more four-carbon diols selected from 1,2-butanediol,
1,3-butanediol, 1,4-butanediol, and 2,3-butanediol; each based on
the total weight of diols, and [0019] (iii) 5 weight percent to 35
weight percent water, based on the total weight of diols and water,
with an extractant, comprising [0020] (i) a hydrophobic solvent
selected from 2-ethylhexanol, cyclohexanol, n-hexanol, methyl
isobutyl ketone, methyl isopropyl ketone, methyl propyl ketone,
diisobutyl ketone, trioctylphosphine oxide, trihexylphosphine
oxide, and mixtures thereof; and [0021] (ii) optionally, a second
modifying hydrophobic solvent selected from hexane, heptane,
octane, decane, benzene, toluene, xylenes, isoparaffinic mixed
hydrocarbons having a boiling range between 90 and 325.degree. C.,
methyl napththalenes, and mixtures thereof; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the three-carbon diols and/or four-carbon diols contained
in the mixed diol stream and an extract phase comprising a major
amount of the three-carbon diols and/or four-carbon diols and a
minor amount of the ethylene glycol contained in the mixed diol
stream; and [0022] (B) separating the raffinate phase and the
extract phase.
[0023] A third embodiment of our invention, is a process for
recovering purified ethylene glycol from a mixed diol stream
comprising ethylene glycol and four-carbon diols, comprising [0024]
(A) extracting the mixed diol stream, comprising [0025] (i) 50
weight percent to 99.99 weight percent, ethylene glycol; [0026]
(ii) 0.01 weight percent to 50 weight percent of one or more
four-carbon diols selected from 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; each based on the total weight
of diols, and [0027] (iii) 0 weight percent to 50 weight percent
water, based on the total weight of diols and water, with an
extractant, comprising [0028] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0029] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the four-carbon diols contained in the mixed diol stream
and an extract phase comprising a major amount of the four-carbon
diols and a minor amount of the ethylene glycol contained in the
mixed diol stream; and [0030] (B) separating the raffinate phase
and the extract phase.
[0031] Our process can also be used, for example, to separate
glycols from the hydrogenolysis of glycerol. A fourth embodiment of
our invention, is a process for recovering diols from a mixed diol
stream, comprising [0032] (A) extracting the mixed diol stream,
comprising [0033] (i) 0.1 weight percent to 50 weight percent of
one or more diols selected from ethylene glycol, 1,2-propanediol,
1,3-propanediol 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and
2,3-butanediol; [0034] (ii) 5 weight percent to 90 weight percent
glycerol; and [0035] (iii) 5 weight percent to 90 weight percent
water; each based on the total weight of the mixed diol stream with
an extractant, comprising [0036] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0037] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the glycerol and a minor amount
of the diols contained in the mixed diol stream and an extract
phase comprising a major amount of the diols and a minor amount of
the glycerol contained in the mixed diol stream; and [0038] (B)
separating the raffinate phase and the extract phase.
[0039] Our process can also be used, for example, to separate
glycols from a fermentation broth. A fifth embodiment of our
invention, is a process for recovering diols from a mixed diol
stream, comprising [0040] (A) extracting the mixed diol stream,
comprising [0041] (i) 0.1 weight percent to 30 weight percent of
ethylene glycol, 1,2-propanediol and 1,3-propanediol,
1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and 2,3-butanediol;
[0042] (ii) 5 to 50 weight percent glucose; and [0043] (iii) 50
weight percent to 90 weight percent water; each based on the total
weight of the mixed diol stream, with an extractant, comprising
[0044] (i) a hydrophobic solvent selected from alkanols having from
6 to 20 carbon atoms, ketones having from 5 to 20 carbon atoms,
esters having from 5 to 20 carbon atoms, ethers having from 5 to 20
carbon atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0045] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the glucose and a minor amount of the diols contained in the
mixed diol stream and an extract phase comprising a major amount of
the diols and a minor amount of the glucose contained in the mixed
diol stream; and [0046] (B) separating the raffinate phase and the
extract phase.
[0047] A sixth embodiment of our invention, is a process for
recovering purified three-carbon diols from a mixed diol stream,
comprising [0048] (A) extracting the mixed diol stream, comprising
[0049] (i) 1 weight percent to 99.5 weight percent of one or more
three-carbon diols selected from 1,2-propanediol and
1,3-propanediol; [0050] (ii) 20 ppm by weight to 99 weight percent
of one or more four-carbon diols selected from 1,2-butanediol,
1,3-butanediol, 1,4-butanediol, and 2,3-butanediol; each based on
the total weight of diols, and [0051] (iii) 0 weight percent to 50
weight percent water, based on the total weight of diols and water,
with an extractant, comprising [0052] (i) a hydrophobic solvent
selected from alkanols having from 6 to 20 carbon atoms, ketones
having from 5 to 20 carbon atoms, esters having from 5 to 20 carbon
atoms, ethers having from 5 to 20 carbon atoms, carboxylic acids
having from 5 to 20 carbon atoms, trialkylphosphine oxides having
from 18 to 48 carbon atoms, and mixtures thereof; and [0053] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the three-carbon diols and a
minor amount of the four-carbon diols contained in the mixed diol
stream and an extract phase comprising a major amount of the
four-carbon diols and a minor amount of the three-carbon diols
contained in the mixed diol stream; and [0054] (B) separating the
raffinate phase and the extract phase.
BRIEF DESCRIPTION OF DRAWINGS
[0055] FIG. 1 is a schematic flow diagram of one embodiment of the
invention in which a mixed diol stream is subjected to forward
extraction with a hydrophobic solvent to produce a raffinate
containing ethylene glycol which is subject to purification via
distillation and an extract which is purified via distillation and
recycled to the forward extraction step.
[0056] FIG. 2 is a schematic flow diagram of another embodiment of
the invention in which the forward extraction zone is operated as a
fractional counter-current extraction, the hydrocarbon solvent in
the extract is recovered via back extraction and recycled to the
forward extraction zone, and the three-carbon diols and four-carbon
diols are recovered in a distillation zone.
DETAILED DESCRIPTION
[0057] The present invention provides a method to separate two-,
three-, and four-carbon diols from a mixed diol stream, comprising
[0058] (A) extracting the mixed diol stream, comprising [0059] (i)
1 weight percent to 99.5 weight percent, ethylene glycol; [0060]
(ii) 20 ppm by weight to 99 weight percent of one or more
three-carbon diols and four-carbon diols selected from
1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; each based on the total weight
of diols, and [0061] (iii) 0 weight percent to 50 weight percent
water, based on the total weight of diols and water, with an
extractant, comprising [0062] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0063] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the three-carbon diols and/or four-carbon diols contained
in the mixed diol stream and an extract phase comprising a major
amount of the three-carbon diols and/or four-carbon diols and a
minor amount of the ethylene glycol contained in the mixed diol
stream; and [0064] (B) separating the raffinate phase and the
extract phase.
[0065] Unless otherwise indicated, all numbers expressing
quantities of ingredients, properties such as molecular weight,
reaction conditions, and so forth used in the specification and
claims are to be understood as being modified in all instances by
the term "about." Accordingly, unless indicated to the contrary,
the numerical parameters set forth in the following specification
and attached claims are approximations that may vary depending upon
the desired properties sought to be obtained by the present
invention. At the very least, each numerical parameter should at
least be construed in light of the number of reported significant
digits and by applying ordinary rounding techniques. Further, the
ranges stated in this disclosure and the claims are intended to
include the entire range specifically and not just the endpoint(s).
For example, a range stated to be 0 to 10 is intended to disclose
all whole numbers between 0 and 10 such as, for example 1, 2, 3, 4,
etc., all fractional numbers between 0 and 10, for example 1.5,
2.3, 4.57, 6.1113, etc., and the endpoints 0 and 10. Also, a range
associated with chemical substituent groups such as, for example,
"C.sub.1 to C.sub.5 hydrocarbons", is intended to specifically
include and disclose C.sub.1 and C.sub.5 hydrocarbons as well as
C.sub.2, C.sub.3, and C.sub.4 hydrocarbons.
[0066] Also, it is to be understood that the mention of one or more
process steps does not preclude the presence of additional process
steps before or after the combined recited steps or intervening
process steps between those steps expressly identified. Moreover,
the lettering of process steps or ingredients is a convenient means
for identifying discrete activities or ingredients and the recited
lettering can be arranged in any sequence, unless otherwise
indicated.
[0067] As used herein, the term "and/or," when used in a list of
two or more items, means that any one of the listed items can be
employed by itself, or any combination of two or more of the listed
items can be employed. For example, if a composition is described
as containing components A, B, and/or C, the composition can
contain A alone; B alone; C alone; A and B in combination; A and C
in combination; B and C in combination; or A, B, and C in
combination.
[0068] As used herein, the term "feed" is intended to have its
commonly understood meaning in the liquid-liquid extraction art,
which is the solution that contains the materials to be extracted
or separated. In the present invention, one example of a "feed" is
a mixture comprised of two or more of ethylene glycol,
1,2-propanediol, 1,3-propanediol, 1,2-butanediol, 2,3-butanediol,
1,3-butandediol, and 1,4-butanediol. In the present invention the
term feed is synonymous with "mixed diol stream". The term
"extraction solvent," as used herein, is intended to be synonymous
with the term "extractant" or "solvent" and is intended to mean the
immiscible liquid that is used in the extraction process to extract
materials or solutes from the feed. The term "extract" is the
immiscible liquid left from the extraction solvent after it has
been contacted with the feed. The term "raffinate" is intended to
mean the liquid phase left from the feed after it has been
contacted with the extraction solvent. The term "wash solvent" is
understood to mean a liquid used to wash or enhance the purity of
the raffinate or extract phase.
[0069] In the present invention, one example of an extraction
solvent is an alkanol containing 6 to 20 carbon atoms such as, for
example, 2-ethylhexanol. The term "alkanol", as used herein, refers
to an alkyl containing 6 to 20 carbon atoms and at least one OH
moiety. Other examples of extraction solvents are "ketones",
"esters", "ethers", "carboxylic acids", and "hydrocarbons" which
are terms well known to those skilled in the art. The extraction
solvent can also contain trialkylphosphine oxides. The term
"trialkylphosphine oxides", as used herein, refers to phosphine
oxides containing three alkyl moieties with a total of 18 to 48
carbon atoms including, but not limited to, trioctylphosphine
oxide, isomeric 24-carbon phosphine oxides, trihexylphosphine
oxide, and isomeric 18-carbon phosphine oxides. The term
"hydrophobic solvent", as used herein, refers to a solvent that
will phase separate when mixed with the mixed diol stream and/or
water. The term a "major amount", as used herein, for example "a
major amount of ethylene glycol contained in the mixed diol stream"
refers to at least 50 weight percent of the ethylene glycol
contained in the mixed diol stream. In a further example, when a
raffinate phase comprises a major amount of the ethylene glycol in
the mixed diol stream, the weight of the ethylene glycol in the
raffinate phase divide by the weight of the ethylene glycol in the
mixed diol stream, on a weight percent basis, is greater than 50
weight percent. The term a "minor amount", as used herein, for
example "a minor amount of ethylene glycol contained in the mixed
diol stream" refers to less than 50 weight percent of the ethylene
glycol contained in the mixed diol stream.
[0070] The process of the invention provides for the separation of
a mixed diol stream. The term "mixed diol stream", as used herein,
is understood to mean a mixture comprising two or more of ethylene
glycol, 1,2-propanediol, 1,3-propanediol, 1,2-butanediol,
2,3-butanediol, 1,3-butandediol, and 1,4-butanediol. The terms
"propanediols" and "three-carbon diols", as used herein, are
understood to mean a mixture comprising one or more of
1,2-propanediol and 1,3-propanediol. The terms "butanediols" and
"four-carbon diols", as used herein, are understood to mean a
mixture comprising one or more of 1,2-butanediol, 2,3-butanediol,
1,3-butandediol, and 1,4-butanediol. The term "based on the total
weight of diols", as used herein, is understood to mean based on
the summation of the amount of ethylene glycol, three-carbon diols,
and four-carbon diols.
[0071] The mixed diol stream of the present invention can be
produced by a variety of reaction methods including, but not
limited to hydrogenation of glycolic acid, glycolate esters,
oligomers of glycolic acid, esters of glycolic acid oligomers, or
mixtures thereof, for example, as disclosed in U.S. Pat. No.
7,615,671; hydrogenolysis of carbohydrates, such as sucrose,
glucose, fructose, cellulose, sorbitol, or mixtures thereof, as
disclosed, for example in U.S. Pat. Nos. 5,210,335, 5,026,927,
6,291,725, and U.S. Pat. Appl. No. 2007123739; hydrogenolysis of
glycerol, as exemplified by U.S. Pat. Nos. 5,276,181, 5,214,219,
and U.S. Pat. Pub. No. 2007123739.
[0072] The mixed diol stream of the present invention may be
derived from the reaction methods described above, but also may
have undergone prior separation methods to prepurify the mixed diol
stream. For example a reactor effluent from the hydrogenation of
glycolate species may undergo distillation to remove low boilers,
such as methanol, or high boilers, such as unreacted glycolic acid
oligomers. Alternatively, at times it may be advantageous to remove
the lowest boiling, non-azeotrope forming propanediols from a
reactor effluent by single-feed fractional distillation, prior to
the extraction steps of the present invention.
[0073] Our process comprises extracting a mixed diol stream that
comprises about 1 to about 99.5 weight percent ethylene glycol and
about 20 ppm to 99 weight percent of one or more three-carbon and
four-carbon diols selected from 1,2-propanediol, 1,3-propanediol,
1,2-butanediol, 2,3-butanediol, 1,3-butandediol, and
1,4-butanediol, each based on the total weight of diols; and 0
weight percent to 50 weight percent water, based on the total
weight of diols and water. In another example, the mixed diol
stream, derived by the hydrogenolysis of sorbitol, comprises about
9 to about 23 weight percent butanediols
(1,2-/1,3-/1,4-/2,3-butanediols), 32 to about 67 weight percent
1,2-propanediol, and about 24 to about 59 weight percent ethylene
glycol. In another example, the mixed diol stream, derived by the
hydrogenolysis of sorbitol glycerol, comprises about 40 to 90
weight percent 1,2-propanediol, about 10 to about 60 weight percent
ethylene glycol, and about 0.1 to about 10 weight percent
1,2-butanediol. In a further example, the mixed diol stream,
derived from the hydrogenolysis of sucrose, comprises about 50 to
about 65 weight percent 1,2-propanediol, about 28 to about 45
weight percent ethylene glycol, and about 5 to about 7 weight
percent 1,2-butanediol. In yet another example, the mixed diol
stream, derived from a prepurification step in which the
1,2-propanediol has been removed by ordinary single-feed
distillation, comprises about 50 to about 99.99 weight percent
ethylene glycol, and about 0.01 to about 50 weight percent
butanediols.
[0074] In an aspect of the invention, the mixed diol stream
comprises 1 weight percent to 99.5 weight percent ethylene glycol,
1 weight percent to 90 weight percent ethylene glycol; 1 weight
percent to 80 weight percent ethylene glycol, 1 weight percent to
70 weight percent ethylene glycol, 10 weight percent to 99.5 weight
percent ethylene glycol, 10 weight percent to 90 weight percent
ethylene glycol, 10 weight percent to 80 weight percent ethylene
glycol, 10 weight percent to 70 weight percent ethylene glycol, 20
weight percent to 99.5 weight percent ethylene glycol, 20 weight
percent to 90 weight percent ethylene glycol, 20 weight percent to
80 weight percent ethylene glycol, 20 weight percent to 70 weight
percent ethylene glycol, or 20 weight percent to 60 weight percent
ethylene glycol; 20 ppm to 99.5 weight percent three-carbon diols
and four-carbon diols, 20 ppm to 90 weight percent three-carbon
diols and four-carbon diols, 20 ppm to 80 weight percent
three-carbon diols and four-carbon diols, 20 ppm to 60 weight
percent three-carbon diols and four-carbon diols, 20 ppm to 40
weight percent three-carbon diols and four-carbon diols, 20 ppm to
30 weight percent three-carbon diols and four-carbon diols, 20 ppm
to 5 weight percent three-carbon diols and four-carbon diols, 20
ppm to 2 weight percent three-carbon diols and four-carbon diols,
0.1 weight percent to 99.5 weight percent three-carbon diols and
four-carbon diols, 0.1 weight percent to 90 weight percent
three-carbon diols and four-carbon diols, 0.1 weight percent to 80
weight percent three-carbon diols and four-carbon diols, 0.1 weight
percent to 60 weight percent three-carbon diols and four-carbon
diols, 0.1 weight percent to 40 weight percent three-carbon diols
and four-carbon diols, 0.1 weight percent to 30 weight percent
three-carbon diols and four-carbon diols, 0.1 weight percent to 5
weight percent three-carbon diols and four-carbon diols, or 0.1
weight percent to 2 weight percent three-carbon diols and
four-carbon diols, each based on the total weight of diols.
[0075] In another aspect of the invention, the mixed diol stream
comprises 1 weight percent to 99.5 weight percent ethylene glycol,
1 weight percent to 90 weight percent ethylene glycol, 1 weight
percent to 80 weight percent ethylene glycol, 1 weight percent to
70 weight percent ethylene glycol, 10 weight percent to 99.5 weight
percent ethylene glycol, 10 weight percent to 90 weight percent
ethylene glycol, 10 weight percent to 80 weight percent ethylene
glycol, 10 weight percent to 70 weight percent ethylene glycol, 20
weight percent to 99.5 weight percent ethylene glycol, 20 weight
percent to 90 weight percent ethylene glycol, 20 weight percent to
80 weight percent ethylene glycol, 20 weight percent to 70 weight
percent ethylene glycol, or 20 weight percent to 60 weight percent
ethylene glycol; 20 ppm to 60 weight percent three-carbon diols, 20
ppm to 40 weight percent three-carbon diols, 20 ppm to 30 weight
percent three-carbon diols, 20 ppm to 5 weight percent three-carbon
diols, 20 ppm to 2 weight percent three-carbon diols, 0.1 weight
percent to 60 weight percent three-carbon diols, 0.1 weight percent
to 40 weight percent three-carbon diols, 0.1 weight percent to 30
weight percent three-carbon diols, 0.1 weight percent to 20 weight
percent three-carbon diols, 0.1 weight percent to 5 weight percent
three-carbon diols, 0.1 weight percent to 2 weight percent
three-carbon diols; and 20 ppm to 60 weight percent four-carbon
diols, 20 ppm to 40 weight percent four-carbon diols, 20 ppm to 30
weight percent four-carbon diols, 20 ppm to 20 weight percent
four-carbon diols, 20 ppm to 5 weight percent four-carbon diols, 20
ppm to 2 weight percent four-carbon diols, 0.1 weight percent to 60
weight percent four-carbon diols, 0.1 weight percent to 40 weight
percent four-carbon diols, 0.1 weight percent to 30 weight percent
four-carbon diols, 0.1 weight percent to 20 weight percent
four-carbon diols, 0.1 weight percent to 5 weight percent
four-carbon diols, or 0.1 weight percent to 2 weight percent
four-carbon diols, each based on the total weight of diols.
[0076] In another aspect of the invention, the mixed diol stream
comprises 5 to 75 weight percent ethylene glycol, 30 weight percent
to 95 weight percent three-carbon diols, and 20 ppm to 10 weight
percent four-carbon diols; or 10 weight percent to 60 weight
percent ethylene glycol, 40 weight percent to 90 weight percent
1,2-propanediol, and 0.1 weight percent to 10 weight percent
1,2-butanediol, each based on the total weight of diols.
[0077] In another aspect of the invention, the mixed diol stream
comprises 20 weight percent to 50 weight percent ethylene glycol,
45 weight percent to 70 weight percent three-carbon diols, and 1
weight percent to 10 weight percent four-carbon diols; or 28 weight
percent to 45 weight percent ethylene glycol, 50 weight percent to
65 weight percent 1,2-propanediol, and 5 weight percent to 7 weight
percent 1,2-butanediol, each based on the total weight of
diols.
[0078] In another aspect of the invention, the mixed diol stream
comprises 10 weight percent to 60 weight percent ethylene glycol,
25 weight percent to 75 weight percent three-carbon diols, and 5
weight percent to 25 weight percent four-carbon diols; or 20 weight
percent to 50 weight percent ethylene glycol, 30 weight percent to
70 weight percent 1,2-propanediol, and 5 weight percent to 25
weight percent four-carbon diols, each based on the total weight of
diols.
[0079] In another aspect of the invention, the mixed diol stream
comprises 40 weight percent to 99.99 weight percent ethylene
glycol, 40 weight percent to 99 weight percent ethylene glycol, 40
weight percent to 90 weight percent ethylene glycol, 40 weight
percent to 80 weight percent ethylene glycol, 50 weight percent to
99.99 weight percent ethylene glycol, 50 weight percent to 99
weight percent ethylene glycol, 50 weight percent to 90 weight
percent ethylene glycol, or 50 weight percent to 80 weight percent
ethylene glycol; and 0.001 weight percent to 60 weight percent
four-carbon diols, 0.001 weight percent to 50 weight percent
four-carbon diols, 0.001 weight percent to 40 weight percent
four-carbon diols, 0.001 weight percent to 30 weight percent
four-carbon diols, 0.001 weight percent to 20 weight percent
four-carbon diols, 0.01 weight percent to 60 weight percent
four-carbon diols, 0.01 weight percent to 50 weight percent
four-carbon diols, 0.01 weight percent to 40 weight percent
four-carbon diols, 0.01 weight percent to 30 weight percent
four-carbon diols, 0.01 weight percent to 20 weight percent
four-carbon diols, 1 weight percent to 60 weight percent
four-carbon diols, 1 weight percent to 50 weight percent
four-carbon diols, 1 weight percent to 40 weight percent
four-carbon diols, 1 weight percent to 30 weight percent
four-carbon diols, or 1 weight percent to 20 weight percent
four-carbon diols, each based on the total weight of diols.
[0080] In another aspect of the invention, the mixed diol stream
comprises 1 weight percent to 99.99 weight percent three-carbon
diols, 1 weight percent to 99 weight percent three-carbon diols, 1
weight percent to 90 weight percent three-carbon diols, 1 weight
percent to 80 weight percent three-carbon diols, 10 weight percent
to 99.99 weight percent three-carbon diols, 10 weight percent to 99
weight percent three-carbon diols, 10 weight percent to 90 weight
percent three-carbon diols, 10 weight percent to 80 weight percent
three-carbon diols; and 20 ppm to 99.99 weight percent four-carbon
diols, 20 ppm to 99 weight percent four-carbon diols, 20 ppm to 90
weight percent four-carbon diols, 20 ppm to 80 weight percent
four-carbon diols, 0.001 weight percent to 99.99 weight percent
four-carbon diols, 0.001 weight percent to 99 weight percent
four-carbon diols, 0.001 weight percent to 90 weight percent
four-carbon diols, 0.001 weight percent to 80 weight percent
four-carbon diols, 0.01 weight percent to 99 weight percent
four-carbon diols, 0.01 weight percent to 90 weight percent
four-carbon diols, 0.01 weight percent to 80 weight percent
four-carbon diols, 0.01 weight percent to 70 weight percent
four-carbon diols, 1 weight percent to 99 weight percent
four-carbon diols, 1 weight percent to 90 weight percent
four-carbon diols, 1 weight percent to 80 weight percent
four-carbon diols, or 1 weight percent to 70 weight percent
four-carbon diols, each based on the total weight of diols.
[0081] In another aspect of the invention, any of the mixed diol
streams above can further comprise water. The water can be present
in the mixed diol stream as received or may be added to the mixed
diol stream. The amount of water, based on the total amount of
diols and water, for example, can range from 0.5 weight percent to
80 weight percent water, 0.5 weight percent to 50 weight percent
water, 0.5 weight percent to 40 weight percent water, 0.5 weight
percent to 25 weight percent water, 1 weight percent to 80 weight
percent water, 1 weight percent to 50 weight percent water, 1
weight percent to 40 weight percent water, 1 weight percent to 25
weight percent water, 5 weight percent to 80 weight percent water,
5 weight percent to 60 weight percent water, 5 weight percent to 50
weight percent water, 5 weight percent to 40 weight percent water,
5 weight percent to 35 weight percent water, 5 weight percent to 25
weight percent water, 5 weight percent to 15 weight percent water,
10 weight percent to 50 weight percent water, or 10 weight percent
to 25 weight percent water.
[0082] The mixed diol stream is contacted with an extractant that
comprises at least one hydrophobic solvent selected from alkanols
having from 6 to 20 carbon atoms, ketones having from 5 to 20
carbon atoms, esters having from 5 to 20 carbon atoms, ethers
having from 5 to 20 carbon atoms, alkyl carbonate esters having
from 3 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof. Some representative
examples of hydrophobic solvents include, but are not limited to,
2-ethylhexanol, n-heptanol, n-hexanol, cyclohexanol,
4-methyl-2-pentanol, n-octanol, n-nonanol, n-decanol, tetradecanol
isomers, 3-methyl-2-butanone, methyl isobutyl ketone (also known as
4-methyl-2-pentanone), methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, isobutylisobutyrate, ethyl acetate,
n-butyl acetate, isobutylacetate, isopropylacetate, n-propyl
acetate, diispropylether, dibutylether, tertiary-amyl methyl ether,
tertiary-butyl methyl ether, trioctylphosphine oxide and isomeric
24-carbon phosphine oxides, trihexylphosphine oxide and isomeric
18-carbon phosphine oxides, and mixtures thereof. For example, in
one aspect of our inventive process, the hydrophobic extraction
solvent comprises 2-ethylhexanol. In another aspect of our
inventive process, the hydrophobic extraction solvent comprises
trioctylphosphine oxide, trihexylphosphine oxide, and/or isomeric
24-carbon and 18-carbon phosphine oxides, as exemplified by the
CYANEX.RTM. solvents, such as CYANEX.RTM. 923 and CYANEX.RTM.921
(available from Cytec Industries, Inc., 5 Garret Mountain Plaza,
Woodland Park, N.J.). In one aspect of the invention, the
hydrophobic solvent may be selected from 2-ethylhexanol,
cyclohexanol, n-hexanol, methyl isobutyl ketone, methyl isopropyl
ketone, methyl propyl ketone, diisobutyl ketone, propylene
carbonate, trioctylphosphine oxide, trihexylphosphine oxide, and
mixtures thereof. The hydrophobic solvent may be selected from
2-ethylhexanol, cyclohexanol, n-hexanol, methyl isobutyl ketone,
methyl isopropyl ketone, methyl propyl ketone, diisobutyl ketone,
trioctylphosphine oxide, trihexylphosphine oxide, and mixtures
thereof. The hydrophobic solvent may be selected from
2-ethylhexanol, cyclohexanol, trioctylphosphine oxide,
trihexylphosphine oxide and mixtures thereof.
[0083] Mixtures of one or more different hydrophobic solvents may
be employed if desired. The amount of hydrophobic extraction
solvent employed is not critical to the subject invention and need
only be that amount sufficient to extract the one or more diols
from the mixed diol stream for any given process and to ensure the
formation of two immiscible liquid phases throughout the extraction
zones. In general, the amount of hydrophobic extraction solvent
employed may range from about 10 percent by weight up to about 500
percent by weight or more based on the total weight of the mixed
diol stream. The use of the high percentage of hydrophobic
extraction solvent may be necessary, for example, when there are
only a limited number of stages in a counter-current extraction
process.
[0084] The hydrophobic solvent of the extractant may further
comprise a second modifying hydrophobic solvent to modify the
physical and transport properties of the extractant. The second
modifying hydrophobic solvent can be selected from hydrocarbons
having from 5 to 20 carbon atoms. Some representative examples of
hydrocarbons include hexane, heptane, octane, decane, benzene,
toluene, xylenes, methyl napththalenes, and mixtures thereof. For
example, the hydrocarbon may comprise isoparaffinic mixed
hydrocarbons having boiling ranges between about 90 and about
325.degree. C., as exemplified by the ISOPAR.TM. solvents
(available from Exxon Chemical Co., Houston, Tex.), such as ISOPAR
C (boiling point range of 98 to 104.degree. C.), ISOPAR E (boiling
point range of 118 to 137.degree. C.), ISOPAR G (boiling point
range of 160 to 176.degree. C.), ISOPAR H (boiling point range of
178 to 188.degree. C.), ISOPAR K (boiling point range of 178 to
197.degree. C.), ISOPAR L (boiling point range of 189 to
207.degree. C.), ISOPAR M (boiling point range of 223 to
254.degree. C.), and ISOPAR V (boiling point range of 273 to
312.degree. C.).
[0085] In some aspects of the invention, the hydrocarbon can be
lower boiling than the other hydrophobic solvent components and,
thus, can be readily separated from the other components by
distillation. If more than one hydrophobic solvent is used as the
extractant, these solvents may or may not form azeotropic mixtures
under distillation conditions employed.
[0086] The relative amounts of the hydrophobic solvent and the
second modifying hydrophobic solvent can be varied to optimize the
extraction. In an aspect of the invention, the extractant comprises
50 weight percent to 100 weight percent of the hydrophobic solvent
and 0 weight percent to 50 weight percent of the second, modifying
hydrophobic solvent; 50 weight percent to 95 weight percent of the
hydrophobic solvent and 5 weight percent to 50 weight percent of
the second, modifying hydrophobic solvent; 60 weight percent to 95
weight percent of the hydrophobic solvent and 5 weight percent to
40 weight percent of the second, modifying hydrophobic solvent, or
70 weight percent to 90 weight percent of the hydrophobic solvent
and 10 weight percent to 30 weight percent of the second, modifying
hydrophobic solvent.
[0087] An example, hydrophobic solvent mixture comprises an alcohol
selected from cyclohexanol, n-hexanol, n-octanol,
4-methyl-2-pentanol, 2-ethylhexanol; and a hydrocarbon selected
from one or more of C9 to C11 alkanes such as n-nonane, n-decane,
n-undecane, ISOPAR G (boiling point range of 160 to 176.degree.
C.), ISOPAR H (boiling point range of 178 to 188.degree. C.),
ISOPAR K (boiling point range of 178 to 197.degree. C.), ISOPAR L
(boiling point range of 189 to 207.degree. C.), or mixtures
thereof. Another example hydrophobic solvent mixture comprises
isomeric trioctylphosphine oxide, isomeric trihexylphosphine oxide,
and mixtures thereof, and a hydrocarbon selected from one or more
of C9 to C11 alkanes such as n-nonane, n-decane, n-undecane, ISOPAR
G (boiling point range of 160 to 176.degree. C.), ISOPAR H (boiling
point range of 178 to 188.degree. C.), ISOPAR K (boiling point
range of 178 to 197.degree. C.), ISOPAR L (boiling point range of
189 to 207.degree. C.), or mixtures thereof.
[0088] If an alcohol is used as the hydrophobic solvent of the
extractant, then at least 5 weight percent water, based on total
weight of mixed diol stream and water, must be introduced into the
first extraction zone to ensure two phases form in the extractor.
In another aspect, wherein an alcohol is used as the hydrophobic
solvent, the amount of water introduced is 5 to 60 weight percent,
based on total weight of mixed diol stream and water. In yet
another aspect, wherein an alcohol is used as the hydrophobic
solvent, the amount of water introduced is 10 to 50 weight percent
based on total weight of mixed diol stream and water.
[0089] As noted above, the optional water introduced into the first
extraction can be present in the mixed diol stream as received. The
optional water can be introduced to the extraction process at one
or more different locations. In one aspect for example, the
optional water can be added to the mixed diol stream. In another
aspect, the water can be introduced into the extractor as a
separate feed. In yet another aspect, the extractor may be operated
as a fractional extractor with one or more water feed points.
[0090] The process of the present invention forms a raffinate phase
comprising a major amount of ethylene glycol and a minor amount of
three-carbon diols and/or four-carbon diols contained in the mixed
diol stream. In an aspect of the invention, greater than 95 weight
percent of the ethylene glycol in the mixed diol stream is
recovered in the raffinate phase. In another aspect, greater than
98 weight percent, greater than 99 weight percent, greater than
99.5 weight percent, or greater than 99.99 weight percent of the
ethylene glycol in the mixed diol stream is recovered in the
raffinate phase.
[0091] The process of the present invention forms an extract phase
comprising a major amount of the three-carbon diols and/or the
four-carbon diols and a minor amount of the ethylene glycol. In an
aspect of the invention greater than 60 weight percent of the
four-carbon diols in the mixed diol stream is recovered in the
extract phase. In another aspect, greater than 70 weight percent,
greater than 80 weight percent, greater than 90 weight percent,
greater than 95 weight percent, greater than 98 weight percent, or
greater than 99 weight percent of the four-carbon diols in the
mixed diol stream is recovered in the extract phase.
[0092] The raffinate phase can be concentrated in ethylene glycol.
The concentration of ethylene glycol, based on the total weight of
diols in the raffinate phase can be greater than 95 weight percent,
or greater than 98 weight percent, or greater than 99 weight
percent, or greater than 99.9 weight percent, or greater than 99.99
weight percent. The concentration of three-carbon diols and
four-carbon diols, based on the total weight of diols in the
raffinate phase, can be less than 5 weight percent, less than 1
weight percent, less than 0.5 weight percent, less than 1000 ppm on
a weight basis, less than 500 ppm on a weight basis, less than 100
ppm on a weight basis, or less than 50 ppm on a weight basis.
[0093] The extraction of the mixed diol stream can be carried out
by any means known in the art to intimately contact two immiscible
liquid phases and to separate the resulting phases after the
extraction procedure. For example, the extraction can be carried
out using columns, centrifuges, mixer-settlers, and miscellaneous
devices. Some representative examples of extractors include
unagitated columns (e.g., spray, baffle tray and packed, perforated
plate), agitated columns (e.g., pulsed, rotary agitated, and
reciprocating plate), mixer-settlers (e.g., pump-settler, static
mixer-settler, and agitated mixer-settler), centrifugal extractors
(e.g., those produced by Robatel, Luwesta, deLaval, Dorr Oliver,
Bird, CINC, and Podbielniak), and other miscellaneous extractors
(e.g., emulsion phase contactor, electrically enhanced extractors,
and membrane extractors). A description of these devices can be
found in the "Handbook of Solvent Extraction", Krieger Publishing
Company, Malabar, Fla., 1991, pp. 275-501. The various types of
extractors may be used alone or in any combination.
[0094] The extraction may be conducted in one or more stages. The
number of extraction stages can be selected in consideration of
capital costs, achieving high extraction efficiency, ease of
operability, and the stability of the starting materials and mixed
diol stream to the extraction conditions. The extraction also can
be conducted in a batch or continuous mode of operation. In a
continuous mode, the extraction may be carried out in a co-current,
a counter-current manner, or as a fractional extraction in which
multiple solvents and/or solvent feed points are used to help
facilitate the separation. The extraction process also can be
conducted in a plurality of separation zones that can be in series
or in parallel.
[0095] The extraction typically can be carried out at a temperature
of about 10 to about 120.degree. C. For example, the extraction can
be conducted at a temperature of about 30 to about 80.degree. C.
The desired temperature range may be constrained further by the
boiling point of the extractant components or water. Generally, it
is undesirable to operate the extraction under conditions where the
extractant boils. In one aspect, the extractor can be operated to
establish a temperature gradient across the extractor in order to
improve the mass transfer kinetics or decantation rates. In another
aspect, the extractor may be operated under sufficient pressure to
prevent boiling.
[0096] In an aspect of the invention, the mixed diol stream is
extracted in a continuous counter-current extractor. The extractant
is fed to the extractor at a location lower than the feed location
of the mixed diol stream. The extractant moves up the
counter-current extractor to form an extract phase exiting the top
of the extractor and comprising a major amount of the three-carbon
diols and/or the four-carbon diols and a minor amount of the
ethylene glycol contained in the mixed diol stream. The mixed diol
stream moves down the counter-current extractor to form the
raffinate phase exiting the bottom of the extractor and comprising
a major amount of the ethylene glycol and a minor amount of the
three-carbon diols and/or the four-carbon diols contained in the
mixed diol stream. In an aspect of the invention the feed ratio of
the extractant to the mixed diol stream ranges from 0.5:1 to 20:1,
or 1:1 to 10:1, or 1:1 to 5:1.
[0097] The mixed diol stream and extractant can be contacted by
fractional extraction methods such as, for example, by fractional
counter-current extraction. As used herein, the term "fractional
counter-current extraction" is intended to include, but is not
limited to, a method for separating a feed stream, e.g., reaction
product fluid, containing two or more substances by charging the
feed stream to a counter-current extraction process between the
points where two immiscible solvents are charged to the extraction
process. The two immiscible solvents should be immiscible over the
entire temperature range of the extraction process. This method is
sometimes referred to as "double solvent extraction." Fractional
counter-current extraction can involve the use of a cascade of
stages, extracting solvents and solution to be extracted entering
at opposite ends of the cascade with the feed phase and hydrophobic
extractant phase flowing counter-currently. Some example fractional
counter-current extraction configurations may be found in Treybal,
Liquid Extraction, 2nd Edition, McGraw-Hill Book Company, New York.
1963, pp. 275-276.
[0098] In an aspect of the invention, the mixed diol stream is
extracted in a continuous fractional counter-current extractor. The
extractant is fed to the extractor at a location lower than the
feed location of the mixed diol stream. A hydrophilic solvent is
fed to the extractor at a location higher than the mixed diol
stream. In an aspect of the invention the feed ratio of the
extractant to the mixed diol stream ranges from 0.5:1 to 20:1, or
1:1 to 10:1, or 1:1 to 5:1 and the feed ratio of the hydrophilic
solvent to the mixed diol stream ranges from 0.05:1 to 2:1, or
0.1:1 to 1.5:1, or 0.1:1 to 0.8:1. The hydrophilic solvent may
comprise water.
[0099] The extraction of the mixed diol stream produces a raffinate
phase comprising a major amount of the lowest-carbon-number diols
and a minor amount of the highest-carbon-number diols contained in
the mixed diol stream and an extract phase comprising a major
amount of the highest-carbon-number diols and a minor amount of the
lowest-carbon-number diols contained in the mixed diol stream. The
raffinate phase and the extract phase may be separated by any phase
separation technology known in the art. The phase separation
techniques can be accomplished in the extractor or in a separate
liquid-liquid separation device. Suitable liquid-liquid separation
devices include, but are not limited to, coalescers, cyclones and
centrifuges. Typical equipment that can be used for liquid-liquid
phase separation devices are described in the Handbook of
Separation process Technology, ISBN 0-471-89558-X, John Wiley &
Sons, Inc., 1987.
[0100] Removal of the extracted diols and recycle of the
hydrophobic extractant is another aspect of the instant invention.
A majority of the three-carbon diols and four-carbon diols can be
removed from the extract phase to form a lean hydrophobic solvent.
The lean hydrophobic solvent can be recycled whereby the extractant
of step (B) comprises at least a portion of the lean hydrophobic
solvent. The removal and recycle process may entail extraction,
distillation or a combination of these unit operations. When
extraction is chosen to produce the lean solvent, the step of
extracting the mixed diol stream is called a forward extraction and
the step of extracting the hydrophobic solvent extract exiting the
forward extraction is called a back extraction. When distillation
is chosen as the diol recovery method, the hydrophobic extractant
is preferentially selected such that at least one component of the
extractant forms a minimum boiling azeotrope with the diol
components contained in the extract phase. Most preferably, the
minimum-boiling azeotrope formed with the diol components is
heterogeneous in nature, i.e., forms two liquid phases upon
condensation.
[0101] In one aspect of the invention, diols contained in the
extract phase are recovered by distillation wherein the diol-laden
extract phase is fed to a distillation column, and the diols are
removed overhead as the minimum-boiling azeotropes between at least
one hydrophobic extractant component and the diol components to
form a distillate product; and the bottoms product comprises a
majority of the hydrophobic extractant components.
[0102] Examples of hydrophobic extractant components that form
azeotropes with two-, three-, and four-carbon diols are
hydrocarbons containing seven to fourteen carbon atoms such as
toluene, p-xylene, o-xylene, m-xylene, ethylbenzene,
1,3,5-trimethylbenzene, 1,2,4-trimethylbenzene, isopropylbenzene,
heptane, n-octane, 2,2-4-trimethyl-pentane, n-nonane, n-decane,
n-undecane, and mixtures thereof.
[0103] Additional exemplary hydrophobic extractant components that
form heterogeneous minimum-boiling azeotropes with ethylene glycol,
butanediols, and propanediols are normal- and iso-paraffinic
hydrocarbons containing six to fourteen carbon atoms and mixtures
thereof, most preferably normal- and iso-paraffinic hydrocarbons
containing nine to eleven carbon atoms and mixtures thereof. For
example, preferable paraffinic hydrocarbons are n-octane,
2,2-4-trimethyl-pentane, n-nonane, n-decane, n-undecane, and
mixtures thereof. The azeotrope-forming component also may comprise
isoparaffinic mixed hydrocarbons having boiling ranges between
about 100 and about 225.degree. C., as exemplified by the
ISOPAR.TM. solvents, such as Isopar E (boiling point range of 118
to 137.degree. C.), ISOPAR G (boiling point range of 160 to
176.degree. C.), ISOPAR H (boiling point range of 178 to
188.degree. C.), ISOPAR K (boiling point range of 178 to
197.degree. C.), ISOPAR L (boiling point range of 189 to
207.degree. C.).
[0104] Optionally, one or more hydrocarbons may be added to the
distillation feed stream or provided as reflux to the distillation
column to enhance the azeotropic separation of the diols. It is
advantageous that the minimum boiling azeotropes formed between the
diols and the hydrophobic extractant component have a high diol
content. Examples of high diol content azeotropes include those
with greater than 5 weight percent diol or greater than 15 weight
percent diol. Examples of hydrophobic solvent and diol azeotropes
are given in the table below where pure component boiling points
(NBP), azeotrope boiling points (Azeo BP), and weight percent of
alkane in the azeotrope are given for ethylene glycol (EG),
butanediol (DBO) and propanediol (PDO) with nonane, decane,
undecane, and 2-ethylhexanol (2-EH) as the solvent:
TABLE-US-00001 NBP, C EG BDO PDO NBP, C 197.1 196.5 187.7 Azeo BP,
C nonane 150.8 144.3 145.3 143.2 Decane 174.3 160.8 162.2 158.7
undecane 195.9 172.7 174.2 169.3 2-EH 184.6 177.1 183.2 178.4 wt %
alkane in azeo nonane 91.7% 89.3% 91.2% Decane 84.2% 80.0% 77.6%
undecane 75.1% 68.6% 60.8% 2-EH 75.0% 82.5% 67.8%
[0105] If the diol and the azeotroping agent do not form two liquid
phases, i.e., do not form a heterogeneous azeotrope, then water may
optionally be added to the distillate product to assist in the
generation of two liquid phases. Water may be added in an amount
equal to 10 to 100 percent by weight of the distillate product.
When water is added, the diols will partition preferentially into a
water-rich phase. The organic phase, largely free of diols may be
returned to the distillation column as reflux. The water-rich phase
may be further treated to remove hydrophobic solvent components by
steam distillation wherein live steam is added to the column, or by
distillation of water-hydrophobic solvent azeotropes as an overhead
product.
[0106] As noted above, when extraction is chosen to produce the
lean solvent, the step of extracting the mixed diol stream is
called a forward extraction and the step of extracting the
hydrophobic solvent extract phase which exits the forward
extraction is called a back extraction. Thus, in another aspect of
the invention, diol components can be removed from the extract
phase into water and a lean solvent recovered via a back extraction
process. Our process also comprises extracting the extract phase
from step (B) with a second extractant comprising water to form a
second extract phase comprising a major amount of the diol
components contained in the extract phase from step (B) and a
second raffinate phase (i.e., lean solvent) comprising a minor
amount of the diol composition contained in the extract phase from
step (B). Typically, the concentration of diol in the second
extract phase can be about 1 to about 50 percent by weight or, in
another example, about 5 to about 20 percent by weight.
[0107] The second extract phase can be passed to a process for
recovery of hydrophobic solvent components, for example by
distillation or steam stripping. The second raffinate phase can be
recycled to the first extraction by combining the second raffinate
phase with the first extractant. The second raffinate phase can be
distilled prior to recycle to produce a hydrophobic solvent
distillate that is subsequently combined with the extractant of
step (A).
[0108] The weight ratio of the second extractant to the first
extract phase from step (B) of our inventive process is about
0.05:1 to about 5:1. Further examples of weight ratios of the
second extractant to the first extract phase are about 0.1:1 to 3:1
and about 0.1:1 to about 2:1.
[0109] The back extraction process can be conducted at a
temperature of about 10 to about 120.degree. C. For example, in one
aspect of the invention, the back extraction step of the invention
is carried out at a temperature of about 30 to about 80.degree.
C.
[0110] The back extraction process can be carried out by any
extraction means known in the art to intimately contact two
immiscible liquid phases and to separate the resulting phases after
the extraction procedure. For example, the back extraction can be
carried out using columns, centrifuges, mixer-settlers, and
miscellaneous devices. The various types of extractors may be used
alone or in any combination.
[0111] The back extraction may be conducted in one or more stages.
The back extraction also can be conducted in a batch or continuous
fashion. In a continuous mode, the back extraction may be carried
out in a co-current, a counter-current manner, or as a fractional
extraction in which multiple solvents and/or solvent feed points
are used to help facilitate the separation. Further, the back
extraction process of this invention can be conducted in a
plurality of separation zones in series or in parallel.
[0112] Optionally, an additional hydrophobic solvent may be
employed to modify the physical and transport properties of the
hydrophobic extract phase prior to introduction into the back
extraction process. This additional hydrophobic solvent can be the
same as the optional, second hydrophobic solvent employed in the
forward extraction zone. The optional addition of the second
hydrophobic extraction solvent can be used to remove any unwanted
relatively hydrophobic components from the hydrophilic extract
phase of the back extractor zone. In one embodiment, the second
hydrophobic extraction solvent is not required, and the back
extractor is operated as a traditional extractor instead of as a
fractional extractor.
[0113] Alternatively, the back extraction process may be operated
in a fractional extraction mode with the additional second
hydrophobic solvent added at a feed point closer to the end of the
extractor where the back extraction raffinate stream exits than the
feed point of the hydrophobic extract phase from the forward
extraction zone. The mass feed ratio of the additional second
hydrophobic solvent to the hydrophobic extract phase from the
forward extraction zone can be between 0:1 and 1.5:1 or between
0.05:1 and 0.45:1.
[0114] The forward extraction of the mixed diol stream also
produces a raffinate phase which, in addition to ethylene glycol,
can comprise three-carbon diols, four-carbon diols, water, and
hydrophobic solvent. The raffinate phase can be further processed
to recover a high-purity ethylene glycol product. For example, the
raffinate phase can be fed to a distillation column where water and
hydrophobic solvent can be separated from the diols. The
hydrophobic solvent can be further processed and/or recycled to the
extractor.
[0115] A further embodiment of our invention is a process for
recovering purified ethylene glycol from a mixed diol stream,
comprising [0116] (A) extracting the mixed diol stream, comprising
[0117] (i) 20 weight percent to 99.5 weight percent, ethylene
glycol; [0118] (ii) 20 ppm by weight to 40 weight percent of one or
more three-carbon diols selected from 1,2-propanediol and
1,3-propanediol, and 20 ppm by weight to 30 weight percent of one
or more four-carbon diols selected from 1,2-butanediol,
1,3-butanediol, 1,4-butanediol, and 2,3-butanediol; each based on
the total weight of diols, and [0119] (iii) 5 weight percent to 35
weight percent water, based on the total weight of diols and water,
with an extractant, comprising [0120] (i) a hydrophobic solvent
selected from 2-ethylhexanol, cyclohexanol, n-hexanol, methyl
isobutyl ketone, methyl isopropyl ketone, methyl propyl ketone,
diisobutyl ketone, trioctylphosphine oxide, trihexylphosphine
oxide, and mixtures thereof; and [0121] (ii) optionally, a second
modifying hydrophobic solvent selected from hexane, heptane,
octane, decane, benzene, toluene, xylenes, isoparaffinic mixed
hydrocarbons having a boiling range between 90 and 325.degree. C.,
methyl napththalenes, and mixtures thereof; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the three-carbon diols and/or four-carbon diols contained
in the mixed diol stream and an extract phase comprising a major
amount of the three-carbon diols and/or four-carbon diols and a
minor amount of the ethylene glycol contained in the mixed diol
stream; and [0122] (B) separating the raffinate phase and the
extract phase.
[0123] The various aspects of mixed diol stream composition, water
content, hydrophobic solvent, second modifying hydrophobic solvent,
weight percent of hydrophobic solvent and second modifying
hydrophobic solvent in the extractant, recovery of ethylene glycol,
three-carbon and/or four-carbon diols in the mixed diol stream to
the raffinate phase, extraction process, extract phase clean-up and
lean solvent recycle, and recovery of high-purity ethylene glycol
from the raffinate phase discussed above apply to the present
embodiment. For example, the mixed diol stream can comprise 20
weight percent to 99.5 weight percent ethylene glycol, 20 weight
percent to 90 weight percent ethylene glycol, 20 weight percent to
80 weight percent ethylene glycol, 20 weight percent to 70 weight
percent ethylene glycol, or 20 weight percent to 60 weight percent
ethylene glycol; 20 ppm to 40 weight percent three-carbon diols, 20
ppm to 30 weight percent three-carbon diols, 0.1 weight percent to
40 weight percent three-carbon diols, 0.1 weight percent to 30
weight percent three-carbon diols, or 0.1 weight percent to 20
weight percent three-carbon diols; and 20 ppm to 40 weight percent
four-carbon diols, 20 ppm to 30 weight percent four-carbon diols,
20 ppm to 20 weight percent four-carbon diols, 0.1 weight percent
to 40 weight percent four-carbon diols, 0.1 weight percent to 30
weight percent four-carbon diols, or 0.1 weight percent to 20
weight percent four-carbon diols, each based on the total weight of
diols. The amount of water in the mixed diol stream, based on the
total weight of diols and water, can range from 5 weight percent to
35 weight percent water, 5 weight percent to 25 weight percent
water, 5 weight percent to 15 weight percent water, 10 weight
percent to 35 weight percent water, or 10 weight percent to 25
weight percent water.
[0124] The extractant can comprises at least one hydrophobic
solvent selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, and diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof. In another aspect,
the hydrophobic solvent can be selected from 2-ethylhexanol,
cyclohexanol, trioctylphosphine oxide, trihexylphosphine oxide, and
mixtures thereof. The optional, second modifying hydrophobic
solvent can be selected from hydrocarbons having from 5 to 20
atoms. The second, modifying hydrophobic solvent can be selected
from hexane, heptane, octane, decane, benzene, toluene, xylenes,
methyl napththalenes, isoparaffinic mixed hydrocarbons having
boiling ranges between about 90 and about 325.degree. C., and
mixtures thereof.
[0125] A third embodiment of our invention, is a process for
recovering purified ethylene glycol from a mixed diol stream
comprising ethylene glycol and four-carbon diols, comprising [0126]
(A) extracting the mixed diol stream, comprising [0127] (i) 50
weight percent to 99.99 weight percent, ethylene glycol; [0128]
(ii) 0.01 weight percent to 50 weight percent of one or more
four-carbon diols selected from 1,2-butanediol, 1,3-butanediol, 1,4
butanediol, and 2,3-butanediol; each based on the total weight of
diols, and [0129] (iii) 0 weight percent to 50 weight percent
water, based on the total weight of diols and water, with an
extractant, comprising [0130] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0131] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the ethylene glycol and a minor
amount of the four-carbon diols contained in the mixed diol stream
and an extract phase comprising a major amount of the four-carbon
diols and a minor amount of the ethylene glycol contained in the
mixed diol stream; and [0132] (B) separating the raffinate phase
and the extract phase.
[0133] The various aspects of mixed diol stream composition, water
content, hydrophobic solvent, second modifying hydrophobic solvent,
weight percent of hydrophobic solvent and second modifying
hydrophobic solvent in the extractant, recovery of ethylene glycol
and/or four-carbon diols in the mixed diol stream to the raffinate
phase, extraction process, extract phase clean-up and lean solvent
recycle, and recovery of high-purity ethylene glycol from the
raffinate phase discussed above apply to the present embodiment.
For example, the mixed diol stream can comprise 50 weight percent
to 99.99 weight percent ethylene glycol, 50 weight percent to 99
weight percent ethylene glycol, 50 weight percent to 95 weight
percent ethylene glycol, 50 weight percent to 90 weight percent
ethylene glycol, 50 weight percent to 80 weight percent ethylene
glycol, 60 weight percent to 99.99 weight percent ethylene glycol,
60 weight percent to 99 weight percent ethylene glycol, 60 weight
percent to 95 weight percent ethylene glycol, 60 weight percent to
90 weight percent ethylene glycol, 60 weight percent to 80 weight
percent ethylene glycol, 70 weight percent to 99.99 weight percent
ethylene glycol, 70 weight percent to 99 weight percent ethylene
glycol, 70 weight percent to 95 weight percent ethylene glycol, 70
weight percent to 90 weight percent ethylene glycol, or 70 weight
percent to 80 weight percent ethylene glycol; and 0.01 weight
percent to 50 weight percent four-carbon diols, 0.01 weight percent
to 40 weight percent four-carbon diols, 0.01 weight percent to 30
weight percent four-carbon diols, 0.01 weight percent to 20 weight
percent four-carbon diols, 0.01 weight percent to 5 weight percent
four-carbon diols, 0.01 weight percent to 2 weight percent
four-carbon diols, 1 weight percent to 50 weight percent
four-carbon diols, 1 weight percent to 40 weight percent
four-carbon diols, 1 weight percent to 30 weight percent
four-carbon diols, 1 weight percent to 20 weight percent
four-carbon diols, 1 weight percent to 5 weight percent four-carbon
diols, 1 weight percent to 2 weight percent four-carbon diols, 5
weight percent to 50 weight percent four-carbon diols, 5 weight
percent to 40 weight percent four-carbon diols, 5 weight percent to
30 weight percent four-carbon diols, or 5 weight percent to 20
weight percent four-carbon diols.
[0134] Our process can also be used, for example, to separate
glycols from the hydrogenolysis of glycerol. A fourth embodiment of
our invention, is a process for recovering diols from a mixed diol
stream, comprising [0135] (A) extracting the mixed diol stream,
comprising [0136] (i) 0.1 weight percent to 50 weight percent of
one or more diols selected from ethylene glycol, 1,2-propanediol,
1,3-propanediol 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and
2,3-butanediol; [0137] (ii) 5 weight percent to 90 weight percent
glycerol; and [0138] (iii) 5 weight percent to 90 weight percent
water; each based on the total weight of the mixed diol stream with
an extractant, comprising [0139] (i) a hydrophobic solvent selected
from alkanols having from 6 to 20 carbon atoms, ketones having from
5 to 20 carbon atoms, esters having from 5 to 20 carbon atoms,
ethers having from 5 to 20 carbon atoms, carboxylic acids having
from 5 to 20 carbon atoms, trialkylphosphine oxides having from 18
to 48 carbon atoms, and mixtures thereof; and [0140] (ii)
optionally, a second modifying hydrophobic solvent selected from
hydrocarbons having from 5 to 20 carbon atoms; to form a raffinate
phase comprising a major amount of the glycerol and a minor amount
of the diols contained in the mixed diol stream and an extract
phase comprising a major amount of the diols and a minor amount of
the glycerol contained in the mixed diol stream; and [0141] (B)
separating the raffinate phase and the extract phase.
[0142] The various aspects of hydrophobic solvent, second modifying
hydrophobic solvent, weight percent of hydrophobic solvent and
second modifying hydrophobic solvent in the extractant apply to the
present embodiment.
[0143] For example, the mixed diol stream can comprise 0.1 weight
percent to 50 weight percent ethylene glycol, 5 weight percent to
50 weight percent ethylene glycol, 10 weight percent to 40 weight
percent ethylene glycol, 10 weight percent to 30 weight percent
ethylene glycol, or 20 weight percent to 40 weight percent ethylene
glycol; 0.1 weight percent to 40 weight percent three-carbon diols,
0.1 weight percent to 30 weight percent three-carbon diols, 1
weight percent to 40 weight percent three-carbon diols, 1 weight
percent to 30 weight percent three-carbon diols, or 1 weight
percent to 20 weight percent three-carbon diols; and 0.1 weight
percent to 40 weight percent four-carbon diols, 0.1 weight percent
to 30 weight percent four-carbon diols, 0.1 weight percent to 20
weight percent four-carbon diols, 1 weight percent to 40 weight
percent four-carbon diols, 1 weight percent to 30 weight percent
four-carbon diols, or 1 weight percent to 20 weight percent
four-carbon diols, each based on the total weight of the mixed diol
stream.
[0144] The amount of glycerol in the mixed diol stream, based on
the total weight of the mixed diol stream, can range from 5 weight
percent to 90 weight percent, 5 weight percent to 70 weight
percent, 5 weight percent to 50 weight percent, 5 weight percent to
25 weight percent, 5 weight percent to 10 weight percent, 10 weight
percent to 90 weight percent, 10 weight percent to 70 weight
percent, 10 weight percent to 50 weight percent, 10 weight percent
to 25 weight percent, 25 weight percent to 90 weight percent, 25
weight percent to 70 weight percent, or 25 weight percent to 50
weight percent.
[0145] The amount of water in the mixed diol stream, based on the
total weight of the mixed diol stream, can range from 5 weight
percent to 90 weight percent, 5 weight percent to 70 weight
percent, 5 weight percent to 50 weight percent, 5 weight percent to
25 weight percent, 5 weight percent to 10 weight percent, 10 weight
percent to 90 weight percent, 10 weight percent to 70 weight
percent, 10 weight percent to 50 weight percent, 10 weight percent
to 25 weight percent, or 25 weight percent to 90 weight percent, 25
weight percent to 70 weight percent, 25 weight percent to 50 weight
percent.
[0146] The process of the present invention forms a raffinate phase
comprising a major amount of the glycerol and a minor amount of the
diols contained in the mixed diol stream. In an aspect of the
present invention, greater than 90 weight percent of the glycerol
is recovered in the raffinate phase. In another aspect, greater
than 95 weight percent, greater than 98 weight percent, greater
than 99 weight percent, or greater than 99.9 weight percent of the
glycerol is recovered in the raffinate phase.
[0147] The process of the present invention forms an extract phase
comprising a major amount of the diols and a minor amount of the
glycerol contained in the mixed diol stream. In an aspect of the
invention, greater than 60 percent of the diols in the mixed diol
stream is recovered in the extract phase. In another aspect,
greater than 70 weight percent, greater than 80 weight percent,
greater than 90 weight percent, greater than 98 weight percent, or
greater than 99 weight percent of the diols in the mixed diol
stream is recovered in the extract phase.
[0148] The extract phase can be back extracted with water to form a
second, aqueous extract phase containing a major amount of diols in
the second, aqueous extract phase and a minor amount of diols in
the second, hydrophobic solvent raffinate phase. The hydrophobic
solvent may be recycled to the first extractor to separate glycerol
and the diols. The aqueous, extract phase can become a new mixed
diol feed to produce purified ethylene glycol and/or three carbon
glycols by the processes described above and below,
respectively.
[0149] Our process can also be used, for example, to separate
glycols from a fermentation broth. A fifth embodiment of our
invention, is a process for recovering diols from a mixed diol
stream, comprising [0150] (A) extracting the mixed diol stream,
comprising [0151] (i) 0.1 weight percent to 30 weight percent of
ethylene glycol, 1,2-propanediol and 1,3-propanediol,
1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and 2,3-butanediol;
[0152] (ii) 5 to 50 weight percent glucose; and [0153] (iii) 50
weight percent to 90 weight percent water; each based on the total
weight of the mixed diol stream, with an extractant, comprising
[0154] (i) a hydrophobic solvent selected from alkanols having from
6 to 20 carbon atoms, ketones having from 5 to 20 carbon atoms,
esters having from 5 to 20 carbon atoms, ethers having from 5 to 20
carbon atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0155] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the glucose and a minor amount of the diols contained in the
mixed diol stream and an extract phase comprising a major amount of
the diols and a minor amount of the glucose contained in the mixed
diol stream; and [0156] (B) separating the raffinate phase and the
extract phase.
[0157] The various aspects of hydrophobic solvent, second modifying
hydrophobic solvent, weight percent of hydrophobic solvent and
second modifying hydrophobic solvent in the extractant apply to the
present embodiment.
[0158] For example, the mixed diol stream can comprise 0.1 weight
percent to 30 weight percent ethylene glycol, 1 weight percent to
30 weight percent ethylene glycol, 1 weight percent to 20 weight
percent ethylene glycol, 5 weight percent to 30 weight percent
ethylene glycol, or 5 weight percent to 20 weight percent ethylene
glycol; 0.1 weight percent to 30 weight percent three-carbon diols,
1 weight percent to 30 weight percent three-carbon diols, 1 weight
percent to 20 weight percent three-carbon diols, 5 weight percent
to 30 weight percent three-carbon diols, or 5 weight percent to 20
weight percent three-carbon diols; and 0.1 weight percent to 30
weight percent four-carbon diols, 1 weight percent to 30 weight
percent four-carbon diols, 1 weight percent to 20 weight percent
four-carbon diols, 5 weight percent to 30 weight percent
four-carbon diols, 5 weight percent to 20 weight percent
four-carbon diols, or 10 weight percent to 20 weight percent
four-carbon diols, each based on the total weight of the mixed diol
stream.
[0159] The amount of glucose in the mixed diol stream, based on the
total weight of the mixed diol stream, can range from 5 weight
percent to 50 weight percent, 5 weight percent to 40 weight
percent, 5 weight percent to 30 weight percent, 5 weight percent to
20 weight percent, 5 weight percent to 10 weight percent, 10 weight
percent to 50 weight percent, 10 weight percent to 40 weight
percent, 10 weight percent to 30 weight percent, 10 weight percent
to 20 weight percent, 25 weight percent to 50 weight percent, 25
weight percent to 40 weight percent, or 25 weight percent to 30
weight percent.
[0160] The amount of water in the mixed diol stream, based on the
total weight of the mixed diol stream, can range from 50 weight
percent to 90 weight percent, 50 weight percent to 80 weight
percent, 50 weight percent to 70 weight percent, 50 weight percent
to 60 weight percent, 60 weight percent to 90 weight percent, 60
weight percent to 80 weight percent, 60 weight percent to 70 weight
percent, 70 weight percent to 90 weight percent, 70 weight percent
to 80 weight percent, or 80 weight percent to 90 weight
percent.
[0161] The process of the present invention forms a raffinate phase
comprising a major amount of the glucose and a minor amount of the
diols contained in the mixed diol stream. In an aspect of the
present invention, greater than 90 weight percent of the glucose is
recovered in the raffinate phase. In another aspect, greater than
95 weight percent, greater than 98 weight percent, greater than 99
weight percent, or greater than 99.5 weight percent of the glucose
is recovered in the raffinate phase.
[0162] The process of the present invention forms an extract phase
comprising a major amount of the diols and a minor amount of the
glucose contained in the mixed diol stream. In an aspect of the
invention, greater than 60 percent of the diols in the mixed diol
stream is recovered in the extract phase. In another aspect,
greater than 70 weight percent, greater than 80 weight percent,
greater than 90 weight percent, greater than 98 weight percent, or
greater than 99 weight percent of the diols in the mixed diol
stream is recovered in the extract phase.
[0163] The extract phase can be back extracted with water to form a
second, aqueous extract phase containing a major amount of diols in
the second, aqueous extract phase and a minor amount of diols in
the second, hydrophobic solvent raffinate phase. The hydrophobic
solvent may be recycled to the first extractor to separate glucose
and the diols. The aqueous, extract phase can become a new mixed
diol feed to produce purified ethylene glycol and/or three carbon
glycols by the processes described above and below,
respectively.
[0164] A sixth embodiment of our invention, is a process for
recovering purified propanediol, from a mixed diol stream
comprising propanediols and butanediols, comprising [0165] (A)
extracting the mixed diol stream, comprising [0166] (i) 1 weight
percent to 99.5 weight percent of one or more three-carbon diols
selected from 1,2-propanediol and 1,3-propanediol; [0167] (ii) 20
ppm by weight to 99 weight percent of one or more four-carbon diols
selected from 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and
2,3-butanediol; each based on the total weight of diols, and [0168]
(iii) 0 weight percent to 50 weight percent water, based on the
total weight of diols and water, with an extractant, comprising
[0169] (i) a hydrophobic solvent selected from alkanols having from
6 to 20 carbon atoms, ketones having from 5 to 20 carbon atoms,
esters having from 5 to 20 carbon atoms, ethers having from 5 to 20
carbon atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0170] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the three-carbon diols and a minor amount of the four-carbon
diols contained in the mixed diol stream and an extract phase
comprising a major amount of the four-carbon diols and a minor
amount of the three-carbon diols contained in the mixed diol
stream; and [0171] (B) separating the raffinate phase and the
extract phase.
[0172] The various aspects of water content in the mixed diol
stream, hydrophobic solvent, second modifying hydrophobic solvent,
weight percent of hydrophobic solvent and second modifying
hydrophobic solvent in the extractant, extraction process, and
extract phase clean-up and lean solvent recycle discussed above
apply to the present embodiment. The mixed diol stream may comprise
1 weight percent to 99.5 weight percent three-carbon diols, 1
weight percent to 95 weight percent three-carbon diols, 1 weight
percent to 90 weight percent three-carbon diols, 1 weight percent
to 80 weight percent three-carbon diols, 1 weight percent to 70
weight percent three-carbon diols, 10 weight percent to 99.5 weight
percent three-carbon diols, 10 weight percent to 95 weight percent
three-carbon diols, 10 weight percent to 90 weight percent
three-carbon diols, 10 weight percent to 80 weight percent
three-carbon diols, 10 weight percent to 70 weight percent
three-carbon diols, 30 weight percent to 99.5 weight percent
three-carbon diols, 30 weight percent to 95 weight percent
three-carbon diols, 30 weight percent to 90 weight percent
three-carbon diols, 30 weight percent to 80 weight percent
three-carbon diols, or 30 weight percent to 70 weight percent
three-carbon diols; and 20 ppm to 99.5 weight percent four-carbon
diols, 20 ppm to 95 weight percent four-carbon diols, 20 ppm to 90
weight percent four-carbon diols, 20 ppm to 80 weight percent
four-carbon diols, 20 ppm to 70 weight percent four-carbon diols, 1
weight percent to 99.5 weight percent four-carbon diols, 1 weight
percent to 95 weight percent four-carbon diols, 1 weight percent to
90 weight percent four-carbon diols, 1 weight percent to 80 weight
percent four-carbon diols, 1 weight percent to 70 weight percent
four-carbon diols, 10 weight percent to 99.5 weight percent
four-carbon diols, 10 weight percent to 95 weight percent
four-carbon diols, 10 weight percent to 90 weight percent
four-carbon diols, 10 weight percent to 80 weight percent
four-carbon diols, 10 weight percent to 70 weight percent
four-carbon diols, 30 weight percent to 99.5 weight percent
four-carbon diols, 30 weight percent to 95 weight percent
four-carbon diols, 30 weight percent to 90 weight percent
four-carbon diols, 30 weight percent to 80 weight percent
four-carbon diols, or 30 weight percent to 70 weight percent
four-carbon diols, each based on the total weight of diols.
[0173] The process of the present invention forms a raffinate phase
comprising a major amount of the three-carbon diols and a minor
amount of the four-carbon diols contained in the mixed diol stream.
In an aspect of the present invention, greater than 95 weight
percent of the three-carbon diols in the mixed diol stream is
recovered in the raffinate phase. In another aspect, greater than
98 weight percent, greater than 99 weight percent, greater than
99.5 weight percent, or greater than 99.99 weight percent of the
three-carbon diols in the mixed diol stream is recovered in the
raffinate phase.
[0174] The process of the present invention forms an extract phase
comprising a major amount of the four-carbon diols and a minor
amount of the three-carbon diols contained in the mixed diol
stream. In an aspect of the invention, greater than 60 weight
percent of the four-carbon diols in the mixed diol stream is
recovered in the extract phase. In another aspect, greater than 70
weight percent, greater than 80 weight percent, greater than 90
weight percent, greater than 95 weight percent, greater than 98
weight percent, or greater than 99 weight percent of the
four-carbon diols in the mixed diol stream is recovered in the
extract phase.
[0175] The raffinate phase can be concentrated in three-carbon
diols. The concentration of the three-carbon diols, based on the
total weight of diols in the raffinate phase, can be greater than
95 weight percent, greater than 98 weight percent, greater than 99
weight percent, greater than 99.9 weight percent, or greater than
99.99 weight percent. The concentration of the four-carbon diols,
based on the total weight of diols in the raffinate phase can be
less than 5 weight percent, less than 1 weight percent, less than
0.5 weight percent, less than 1000 ppm on a weight basis, less than
500 ppm on a weight basis, or less than 100 ppm on a weight
basis.
[0176] The forward extraction of the mixed diol stream also
produces a raffinate phase which, in addition to three-carbon
diols, can comprise four-carbon diols, water, and hydrophobic
solvent. The raffinate phase can be further processed to recover a
high-purity three-carbon diol product. For example, the raffinate
phase can be fed to a distillation column where water and
hydrophobic solvent can be separated from the three-carbon diols.
The hydrophobic solvent can be further processed and/or recycled to
the extractor.
[0177] FIGS. 1 and 2 present two, non-limiting embodiments of the
instant invention, described herein in detail. In a first
embodiment of the invention as laid out in FIG. 1, Mixed Diol Feed
Stream 6 is fed counter-currently to Forward Extractor 1, wherein
the stream is immediately contacted with Extractant Stream 21. Two
products exit Forward Extractor 1, the Hydrophilic Raffinate
Product Stream 8, depleted of higher-number-carbon diols, and
Hydrophobic Extract Product Stream 7. An additional hydrophobic
solvent Stream 14, preferably one that forms an azeotrope with the
higher-carbon-number diols, can be mixed with Stream 7 before
Stream 7 is fed to a distillation column, Solvent Column 2. A Lean
Hydrophobic Solvent Stream 19, reduced in the amount of diols,
exits as the bottoms product of Solvent Column 2. Lean Hydrophobic
Solvent Stream 19 is recycled back to Forward Extractor 1: Stream
19 is combined with Solvent Make-up Stream 20 to produce Extractant
Stream 21 which is fed to Forward Extractor 1. An azeotropic
composition comprising diols, hydrophobic solvent, and/or water
exits the top of Solvent Column 2 as Stream 15. Stream 15 is
condensed and phases are allowed to separate in Decanter 3. Part of
the hydrophobic phase is refluxed back to Solvent Column 2 as
Stream 18 and part can be purged or sent for further processing as
Stream 16. The hydrophilic phase, containing the majority of the
diols, can be sent for further processing as Stream 17.
[0178] Raffinate Hydrophilic Product Stream 8 from Forward
Extractor 1 is rich in ethylene glycol. Stream 8 can be sent to a
distillation column, Refining Column 4, to produce a purified
ethylene glycol bottoms Stream 13. Stream 9, exiting the top of
Refining Column 4 can comprise water, hydrophobic solvent,
higher-carbon-number diols, and/or ethylene glycol. Stream 9 is
condensed and allowed to phase separate in Decanter 5. Part of the
hydrophobic phase is refluxed back to Refining Column 4 as Stream
12 and part can be purged or sent for further processing as Stream
10. The hydrophilic phase can be sent for further processing as
Stream 11.
[0179] In the previously described first embodiment of the instant
invention, conventional extraction, i.e., extraction involving a
single solvent feed point is utilized for the forward extraction
zone. It may be advantageous, however, to operate the forward
extraction zone as a fractional counter-current extraction in which
additional hydrophobic solvent components or hydrophilic solvent
components are introduced as separate feeds. In a second embodiment
of the invention as set forth in FIG. 2, Hydrophilic Solvent Stream
6 is optionally split into Stream 7 and Stream 8 wherein Stream 8
is combined with Mixed Diol Feed Stream 5 to produce Stream 21.
Stream 21 is fed counter-currently to Forward Extractor 1, wherein
the stream is intimately contacted with Hydrophobic Solvent Stream
20. When operated as a fractional extractor, Stream 7 is introduced
into Forward Extractor 1 above feed Stream 21. Two products exit
Forward Extractor 1, the Hydrophilic Raffinate Diol Product Stream
10 rich in ethylene glycol and the Hydrophobic Solvent Extract
Stream 9 rich in higher-carbon-number diols. The purpose of feed
Stream 7 is to further reduce losses of lower-carbon-number diols
(e.g., ethylene glycol) into Stream 9. Stream 9 is fed
counter-currently to a second extraction zone, Back Extractor 2,
wherein the stream is intimately contacted with Water Stream 11.
Two products are withdrawn from Back Extractor 2, the Hydrophobic
Raffinate Stream 12 comprising the lean hydrophobic solvent which
is recycled to Forward Extractor 1, and the Hydrophilic Extract
Stream 13 comprising higher-carbon-number diols. Stream 13 is
refined via distillation in Solvent Column 3. Bottoms product,
Stream 18, comprises water and diols. Stream 14 exiting the top of
Solvent Column 3 is condensed and the phases are allowed to
separate in Decanter 4. Part of the hydrophobic phase is refluxed
to Solvent Column 3 in Stream 17 and part of the hydrophobic phase
is purged or sent for further processing in Stream 15. A
hydrophilic phase is purged or sent for further processing in
Stream 16.
[0180] The efficiency of the extraction process of the invention
can be measured by a partition coefficient, abbreviated herein as
"P(A)" of a diol component "A" which is defined as the
concentration of diol component "A" in the hydrophobic phase
divided by the concentration of diol component "A" in the
hydrophilic phase. The partition coefficient may be determined by
analysis of diol component "A" by known methods such as, for
example, gas chromatography.
[0181] When the one or more higher-carbon-number diols ("H") are
partitioned between the hydrophilic phase and the hydrophobic phase
by the extraction processes of the invention, the P(H) value of
diol component "H" can be maintained at a level greater than about
0.4, greater than about 0.5, or greater than about 0.7, depending
on the efficiency of the extraction process. If the P(H) value is
high, diol component "H" will preferentially distribute into the
hydrophobic phase. Similarly, the efficiency of the extraction
process can be measured by a partition coefficient of one or more
lower-carbon-number diols ("L"). The partition coefficient P(L)
value of diol component "L" can be less than about 0.5, less than
about 0.4, or less than about 0.25, depending on the efficiency of
the extraction process. For example, if a mixture of ethylene
glycol, 1,2-propanediol, 1,2-butane diol, and water are vigorously
mixed with a hydrophobic solvent and allowed to phase separate, the
1,2-butanediol can desirably have a partition coefficient
P(1,2-BDO) greater than about 0.4, greater than about 0.5, or
greater than 0.7 and ethylene glycol can desirably have a partition
coefficient P(EG) less than 0.5, less than 0.4, or less than
0.25.
[0182] In an aspect, the extraction process of this invention can
be conducted in a manner such that a separation criterion is
satisfied. The criterion referred to herein as selectivity between
diol components "H" and "L", is based on ratio of the partition
coefficients defined above. For example, the selectivity ("S")
between "H" and "L" is a partition coefficient ratio, S=P(H)/P(L).
The S value for this ratio can be maintained at a level greater
than about 1.5. Other values of S include greater than about 2.2
and greater than about 3.0. If the S value is high, the extraction
will effectively and efficiently separate the key
higher-carbon-number diol components and lower-carbon-number diol
components, "H" and "L", into the extract and raffinate phases
respectively.
[0183] The invention also includes the following non-limiting
embodiments that are set forth below.
[0184] A First Embodiment is a process for recovering purified
ethylene glycol from a mixed diol stream, comprising [0185] (A)
extracting the mixed diol stream, comprising [0186] (i) 1 weight
percent to 99.5 weight percent, ethylene glycol; [0187] (ii) 20 ppm
by weight to 99 weight percent of one or more three-carbon diols
and four-carbon diols selected from 1,2-propanediol,
1,3-propanediol, 1,2-butanediol, 1,3-butanediol, 1,4-butanediol,
and 2,3-butanediol; each based on the total weight of diols, and
[0188] (iii) 0 weight percent to 50 weight percent water, based on
the total weight of diols and water, with an extractant, comprising
[0189] (i) a hydrophobic solvent selected from alkanols having from
6 to 20 carbon atoms, ketones having from 5 to 20 carbon atoms,
esters having from 5 to 20 carbon atoms, ethers having from 5 to 20
carbon atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0190] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; [0191] to form a raffinate phase comprising a major
amount of the ethylene glycol and a minor amount of the
three-carbon diols and/or four-carbon diols contained in the mixed
diol stream and an extract phase comprising a major amount of the
three-carbon diols and/or four-carbon diols and a minor amount of
the ethylene glycol contained in the mixed diol stream; and [0192]
(B) separating the raffinate phase and the extract phase.
[0193] The process of the First Embodiment wherein the mixed diol
stream comprises 20 weight percent to 99.5 weight percent ethylene
glycol, 20 ppm by weight to 40 weight percent of three-carbon
diols, and 20 ppm by weight to 30 weight percent four-carbon
diols.
[0194] The process of the First Embodiment wherein the mixed diol
stream comprises 10 weight percent to 60 weight percent ethylene
glycol, 40 weight percent to 90 weight percent three-carbon diols,
and 0.1 weight percent to 10 weight percent four-carbon diols.
[0195] The process of the First Embodiment wherein the mixed diol
stream comprises 20 weight percent to 45 weight percent ethylene
glycol, 50 weight percent to 65 weight percent three-carbon diols,
and 3 weight percent to 9 weight percent four-carbon diols.
[0196] The process of the First Embodiment wherein the mixed diol
stream comprises 20 weight percent to 60 weight percent ethylene
glycol, 30 weight percent to 70 weight percent three-carbon diols,
and 5 weight percent to 25 weight percent four-carbon diols.
[0197] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
mixed diol stream comprises from 0.5 weight percent to 25 weight
percent water, 5 weight percent to 50 weight percent water, 5
weight percent to 35 weight percent water, 10 weight percent to 40
weight percent water, or 15 weight percent to 35 weight percent
water.
[0198] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
hydrophobic solvent is selected from 2-ethylhexanol, cyclohexanol,
n-hexanol, methyl isobutyl ketone, methyl isopropyl ketone, methyl
propyl ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
[0199] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
hydrophobic solvent is selected from 2-ethylhexanol, cyclohexanol,
trioctylphosphine oxide, trihexylphosphine oxide, and mixtures
thereof.
[0200] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
hydrophobic solvent is selected from 2-ethylhexanol,
trioctylphosphine oxide, trihexylphosphine oxide, and mixtures
thereof.
[0201] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
second modifying hydrophobic solvent is selected from hexane,
heptane, octane, decane, benzene, toluene, xylenes, isoparaffinic
mixed hydrocarbons having a boiling range between 90 and
325.degree. C., methyl napththalenes, and mixtures thereof.
[0202] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
second modifying hydrophobic solvent is selected from heptane,
decane, isoparaffinic mixed hydrocarbons having a boiling range
between 90 and 325.degree. C., and mixtures thereof.
[0203] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
extractant comprises 50 weight percent to 100 weight percent of
said hydrophobic solvent and 0 weight percent to 50 weight percent
of said second modifying hydrophobic solvent, or 60 weight percent
to 95 weight percent of said hydrophobic solvent and 5 weight
percent to 40 weight percent of said second modifying hydrophobic
solvent, or 70 weight percent to 90 weight percent of said
hydrophobic solvent and 10 weight percent to 30 weight percent of
said second modifying hydrophobic solvent.
[0204] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein greater
than 95 weight percent, or greater than 98 weight percent, or
greater than 99 weight percent, or greater than 99.5 weight
percent, or greater than 99.9 weight percent of said ethylene
glycol in said mixed diol stream is recovered in said raffinate
phase.
[0205] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein greater
than 80 weight percent, or greater than 85 weight percent, or
greater than 90 weight percent, or greater than 95 weight percent,
or greater than 98 weight percent, or greater than 99 weight
percent, or greater than 99.9 weight percent of said four-carbon
diols are recovered in said extract phase.
[0206] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein the
purity of said ethylene glycol in said raffinate phase is greater
than 95 weight percent, or greater than 98 weight percent, or
greater than 99 weight percent, or greater than 99.9 weight
percent, or greater than 99.99 weight percent, based the total
weight of said diols.
[0207] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein the total
amount of said three-carbon diols and said four-carbon diols in
said raffinate phase is less than 5 weight percent, less than 1
weight percent, less than 0.5 weight percent, less than 1000 ppm by
weight, less than 500 ppm by weight, or less than 100 ppm by
weight, based on the total weight of said diols.
[0208] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, and wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1.
[0209] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, and wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1, further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream and
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1.
[0210] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, and wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1, further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream and
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1, and wherein the hydrophilic stream comprises water.
[0211] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, and wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1, wherein said hydrophilic solvent comprises water,
and wherein said extraction occurs in said extractor over 4 to 20
theoretical stages, or over 6 to 18 theoretical stages, or over 10
to 15 theoretical stages.
[0212] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, further
comprising removing a majority of said three-carbon diols and said
four-carbon diols from said extract phase to form a lean solvent
and recycling said lean solvent, whereby said extractant comprises
at least a portion of said lean solvent.
[0213] The process of the First Embodiment or the First Embodiment
with any one or more of the intervening features, further
comprising removing a majority of said three-carbon diols and said
four-carbon diols from said extract phase to form a lean solvent
and recycling said lean solvent whereby said extractant comprises
at least a portion of said lean solvent, wherein the removing
occurs through back extraction or through distillation.
[0214] A Second Embodiment is a process for recovering purified
ethylene glycol from a mixed diol stream, comprising [0215] (A)
extracting the mixed diol stream, comprising [0216] (i) 20 weight
percent to 99.5 weight percent, ethylene glycol; [0217] (ii) 20 ppm
by weight to 40 weight percent of one or more three-carbon diols
selected from 1,2-propanediol and 1,3-propanediol, and 20 ppm by
weight to 30 weight percent of one or more four-carbon diols
selected from 1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and
2,3-butanediol; each based on the total weight of diols, and [0218]
(iii) 5 weight percent to 35 weight percent water, based on the
total weight of diols and water, with an extractant, comprising
[0219] (i) a hydrophobic solvent selected from 2-ethylhexanol,
cyclohexanol, n-hexanol, methyl isobutyl ketone, methyl isopropyl
ketone, methyl propyl ketone, diisobutyl ketone, trioctylphosphine
oxide, trihexylphosphine oxide, and mixtures thereof; and [0220]
(ii) optionally, a second modifying hydrophobic solvent selected
from hexane, heptane, octane, decane, benzene, toluene, xylenes,
isoparaffinic mixed hydrocarbons having a boiling range between 90
and 325.degree. C., methyl napththalenes, and mixtures thereof;
[0221] to form a raffinate phase comprising a major amount of the
ethylene glycol and a minor amount of the three-carbon diols and/or
four-carbon diols contained in the mixed diol stream and an extract
phase comprising a major amount of the three-carbon diols and/or
four-carbon diols and a minor amount of the ethylene glycol
contained in the mixed diol stream; and [0222] (B) separating the
raffinate phase and the extract phase.
[0223] The process of the Second Embodiment wherein greater than 95
weight percent, or greater than 99 weight percent, or greater than
99.5 weight percent of said ethylene glycol in said mixed diol
stream is recovered in said raffinate phase, and wherein greater
than 60 weight percent, or greater than 80 weight percent, or
greater than 90 weight percent of said four-carbon diols is
recovered in said extract phase, and wherein the concentration of
said ethylene glycol in said raffinate phase is greater than 95
weight percent, or greater than 99 weight percent, or greater than
99.5 weight percent and the concentration of said three-carbon
diols and said four-carbon diols combined in said raffinate is less
than 1 weight percent, or less than 1000 ppm, or less than 500 ppm,
each based on the total weight of said diols.
[0224] The process of the Second Embodiment or the Second
Embodiment with any one or more of the intervening features wherein
said extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1; further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1; and wherein said hydrophilic stream comprises water.
[0225] A Third embodiment is a process for recovering purified
ethylene glycol from a mixed diol stream comprising ethylene glycol
and four-carbon diols, comprising [0226] (A) extracting the mixed
diol stream, comprising [0227] (i) 50 weight percent to 99.99
weight percent ethylene glycol; [0228] (ii) 0.01 weight percent to
50 weight percent of one or more four-carbon diols selected from
1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and 2,3-butanediol;
each based on the total weight of diols, and [0229] (iii) 0 weight
percent to 50 weight percent water, based on the total weight of
diols and water, with an extractant, comprising [0230] (i) a
hydrophobic solvent selected from alkanols having from 6 to 20
carbon atoms, ketones having from 5 to 20 carbon atoms, esters
having from 5 to 20 carbon atoms, ethers having from 5 to 20 carbon
atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0231] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the ethylene glycol and a minor amount of the four-carbon diols
contained in the mixed diol stream and an extract phase comprising
a major amount of the four-carbon diols and a minor amount of the
ethylene glycol contained in the mixed diol stream; and [0232] (B)
separating the raffinate phase and the extract phase.
[0233] The process of the Third Embodiment wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
[0234] The process of the Third Embodiment or the Third Embodiment
with any one or more of the intervening features wherein greater
than 95 weight percent, greater than 99 weight percent, or greater
than 99.5 weight percent of said ethylene glycol in said mixed diol
stream is recovered in said raffinate phase, and wherein greater
than 60 weight percent, or greater than 80 weight percent, or
greater than 90 weight percent of said four-carbon diols is
recovered in said extract phase, and wherein the concentration of
said ethylene glycol in said raffinate phase is greater than 95
weight percent, or greater than 99 weight percent, or greater than
99.5 weight percent and the concentration of said four-carbon diols
in said raffinate is less than 1 weight percent, or less than 1000
ppm, or less than 500 ppm, each based on the total weight of said
diols.
[0235] The process of the Third Embodiment or the Third Embodiment
with any one or more of the intervening features wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1; further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1; and wherein said hydrophilic stream comprises water.
[0236] A Fourth Embodiment of our invention, is a process for
recovering diols from a mixed diol stream, comprising [0237] (A)
extracting the mixed diol stream, comprising [0238] (i) 0.1 weight
percent to 50 weight percent of one or more diols selected from
ethylene glycol, 1,2-propanediol, 1,3-propanediol 1,2-butanediol,
1,3-butanediol, 1,4-butanediol, and 2,3-butanediol; [0239] (ii) 5
weight percent to 90 weight percent glycerol; and [0240] (iii) 5
weight percent to 90 weight percent water; each based on the total
weight of the mixed diol stream with an extractant, comprising
[0241] (i) a hydrophobic solvent selected from alkanols having from
6 to 20 carbon atoms, ketones having from 5 to 20 carbon atoms,
esters having from 5 to 20 carbon atoms, ethers having from 5 to 20
carbon atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0242] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the glycerol and a minor amount of the diols contained in the
mixed diol stream and an extract phase comprising a major amount of
the diols and a minor amount of the glycerol contained in the mixed
diol stream; and [0243] (B) separating the raffinate phase and the
extract phase.
[0244] The process of the Fourth Embodiment wherein said
hydrophobic solvent is selected from 2-ethylhexanol, cyclohexanol,
n-hexanol, methyl isobutyl ketone, methyl isopropyl ketone, methyl
propyl ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
[0245] The process of the Fourth Embodiment or the Fourth
Embodiment with any one or more intervening features wherein
greater than 90 weight percent, greater than 95 weight percent,
greater than 98 weight percent, greater than 99 weight percent, or
greater than 99.5 weight percent of said glycerol is recovered in
said raffinate phase and wherein greater than 60 weight percent,
greater than 70 weight percent, greater than 80 weight percent,
greater than 90 weight percent, greater than 98 weight percent, or
greater than 99 weight percent of said diols is recovered in said
extract phase.
[0246] The process of the Fourth Embodiment or the Fourth
Embodiment with any one or more of the intervening features wherein
said extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1; further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1, and wherein said hydrophilic stream comprises water.
[0247] A Fifth Embodiment of our invention, is a process for
recovering diols from a mixed diol stream, comprising [0248] (A)
extracting the mixed diol stream, comprising [0249] (i) 0.1 weight
percent to 30 weight percent of ethylene glycol, 1,2-propanediol
and 1,3-propanediol, 1,2-butanediol, 1,3-butanediol,
1,4-butanediol, and 2,3-butanediol; [0250] (ii) 5 to 50 weight
percent glucose; and [0251] (iii) 50 weight percent to 90 weight
percent water; each based on the total weight of the mixed diol
stream, with an extractant, comprising [0252] (i) a hydrophobic
solvent selected from alkanols having from 6 to 20 carbon atoms,
ketones having from 5 to 20 carbon atoms, esters having from 5 to
20 carbon atoms, ethers having from 5 to 20 carbon atoms,
carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0253] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the glucose and a minor amount of the diols contained in the
mixed diol stream and an extract phase comprising a major amount of
the diols and a minor amount of the glucose contained in the mixed
diol stream; and [0254] (B) separating the raffinate phase and the
extract phase.
[0255] The process of the Fifth Embodiment wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
[0256] The process of the Fifth Embodiment or the Fifth Embodiment
with any one or more of the intervening features wherein greater
than 90 weight percent, greater than 95 weight percent, greater
than 98 weight percent, greater than 99 weight percent, or greater
than 99.5 weight percent of said glucose is recovered in said
raffinate phase and wherein greater than 60 weight percent, greater
than 70 weight percent, greater than 80 weight percent, greater
than 90 weight percent, greater than 98 weight percent, or greater
than 99 weight percent of diols is recovered in said extract
phase.
[0257] The process of the Fifth Embodiment or the Fifth Embodiment
with any one or more of the intervening features wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1; further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1, and wherein said hydrophilic stream comprises water.
[0258] A Sixth Embodiment is a process for recovering purified
three-carbon diols from a mixed diol stream comprising propanediols
and butanediols, comprising [0259] (A) extracting the mixed diol
stream, comprising [0260] (i) 1 weight percent to 99.5 weight
percent of one or more three-carbon diols selected from
1,2-propanediol and 1,3-propanediol; [0261] (ii) 20 ppm by weight
to 99 weight percent of one or more four-carbon diols selected from
1,2-butanediol, 1,3-butanediol, 1,4-butanediol, and 2,3-butanediol;
each based on the total weight of diols, and [0262] (iii) 0 weight
percent to 50 weight percent water, based on the total weight of
diols and water, with an extractant, comprising [0263] (i) a
hydrophobic solvent selected from alkanols having from 6 to 20
carbon atoms, ketones having from 5 to 20 carbon atoms, esters
having from 5 to 20 carbon atoms, ethers having from 5 to 20 carbon
atoms, carboxylic acids having from 5 to 20 carbon atoms,
trialkylphosphine oxides having from 18 to 48 carbon atoms, and
mixtures thereof; and [0264] (ii) optionally, a second modifying
hydrophobic solvent selected from hydrocarbons having from 5 to 20
carbon atoms; to form a raffinate phase comprising a major amount
of the three-carbon diols and a minor amount of the four-carbon
diols contained in the mixed diol stream and an extract phase
comprising a major amount of four four-carbon diols and a minor
amount of the three-carbon diols contained in the mixed diol
stream; and [0265] (B) separating the raffinate phase and the
extract phase.
[0266] The process of the Sixth Embodiment wherein said hydrophobic
solvent is selected from 2-ethylhexanol, cyclohexanol, n-hexanol,
methyl isobutyl ketone, methyl isopropyl ketone, methyl propyl
ketone, diisobutyl ketone, trioctylphosphine oxide,
trihexylphosphine oxide, and mixtures thereof.
[0267] The process of the Sixth Embodiment or the Sixth Embodiment
with any one or more of the intervening features wherein greater
than 95 weight percent, greater than 99 weight percent, or greater
than 99.5 weight percent of said three-carbon diols in said mixed
diol stream is recovered in said raffinate phase, and wherein
greater than 60 weight percent, or greater than 80 weight percent,
or greater than 90 weight percent of said four-carbon diols is
recovered in said extract phase, and wherein the concentration of
said three-carbon diols in said raffinate phase is greater than 95
weight percent, or greater than 99 weight percent, or greater than
99.5 weight percent and the concentration of said four-carbon diols
in said raffinate is less than 1 weight percent, or less than 1000
ppm, or less than 500 ppm, each based on the total weight of said
diols.
[0268] The process of the Sixth Embodiment or the Sixth Embodiment
with any one or more of the intervening features wherein said
extraction occurs in a continuous counter-current extractor,
wherein said extractant is fed lower to said extractor than said
mixed diol stream, wherein the feed ratio of said extractant to
said mixed diol stream ranges from 0.5:1 to 20:1, or 1:1 to 10:1,
or 1:1 to 5:1; further comprising feeding a hydrophilic stream to
said extractor at a higher level than said mixed diol stream,
wherein the feed ratio of said hydrophilic stream to said mixed
diol stream ranges from 0.05:1 to 2:1, or 0.1:1 to 1.5:1, or 0.1:1
to 0.8:1; and wherein said hydrophilic stream comprises water.
[0269] The invention is further illustrated by the following,
non-limiting examples.
EXAMPLES
General
[0270] Analyses of mixed diol products and various extraction
phases were carried out by gas chromatography ("GC") using the
following procedure. The components from the glycolic acid
hydrogenation reaction were first reacted with BSTFA
[N,O-bis(trimethylsilyl)trifluoroacetamide] in the presence of
pyridine to the corresponding TMS-derivatives including water,
which were then separated and quantified by an internal standard
(decane) wt % calibrated GC method. The sample to derivatization
reagent (BSTFA and pyridine) ratio was 0.1 g:1 ml:0.2 ml in a GC
vial, which was heated at 80.degree. C. for 30 minutes to ensure
complete derivatization. The GC method used a DB-1301 capillary
column or equivalent (6% cyanopropylphenyl/94% dimethylpolysiloxane
stationary phase, 60 meters.times.0.32 mm ID.times.1.0 um film
thickness), a split injector (280.degree. C.), a flame ionization
detector (300.degree. C.), helium carrier gas at a constant linear
velocity of 27 cm/sec (a Shimadzu GC 2010 or equivalent) or at an
initial column head pressure of 17 psi, an oven temperature program
of 80.degree. C. initial temp for 6 min, 4.degree. C./min temp ramp
rate to 150.degree. C. for 0 min and 10.degree. C./min temp ramp
rate to 290.degree. C. for 17.5 min final hold time. 1-ul of the
prepared sample solution was injected with a split ratio of 40:1.
The method provided quantification range of 0.01-100 wt % for each
analyte within its separation capability.
[0271] For all extraction examples the partition coefficient for
component A is defined as follows:
P ( A ) = Weight Percent A in Hydrophobic phase Weight Percent A in
Hydrophilic phase ##EQU00001##
Selectivity between components A and B is defined as:
S(AB)=P(A)/P(B)
Throughout the examples, the following abbreviations are used in
the Tables:
TABLE-US-00002 Compound Abbreviation
(2-(butoxymethyl)-2-((diphenylphosphino)methyl)propane- BuO-triphos
1,3-diyl)-bis(diphenylphosphine) Ethylene glycol EG 1,3-Butanediol
1,3-BDO 1,2-Butanediol 1,2-BDO 1,4-Butanediol 1,4-BDO
2,3-Butanediol 2,3-BDO 1,2-Propanediol 1,2-PDO 1,3-Propanediol
1,3-PDO Cyanex 923 C923 2-Ethylhexanol 2-EH Isobutyl isobutyrate
IBIB Methyl isobutyl ketone MIBK Diisopropyl ether DIPE Ethyl
acetate EA n-butyl acetate NBA Isobutyl acetate IBA Isopropyl
acetate IPA n-propyl acetate NPA Ethylhexyl acetate EHA Ethyl
propionate EP Methyl valerate MV n-propylpropionate NPP Methyl
propionate MP Methyl butyrate MB 5-ethyl-2-nonanone 5E2N
2-heptanone MAK Diisobutyl ketone DIBK 3-methyl-2-butanone MIPK
6-methyl-2-hexanone MIAK TXIB TXIB Tert-butyl methyl ether MTBE
Dibutyl ether DBE Diethyleneglycol dibutyl ether DEGDBE Toluene TOL
2-pentanone MPK Propylene carbonate PC N-Hexanol NH Cyclohexanol CH
Isophorone IPH n-Decanol ND n-Heptane HEP
[0272] Glycolic Acid/Ester Feed and Extractant Mixture--
[0273] A mixture glycolic acid and glycolate esters was prepared by
heating a mixture of 4000 g of glycolic acid and 1795 grams of
ethylene glycol at a temperature of about 100 to about 150.degree.
C. under atmospheric pressure while removing the water with a
Dean-Stark trap. After approximately 860 g of water were removed,
the reaction pressure was lowered to 25 torr and the reaction was
continued until a total 947 g of water were collected. Mixtures of
glycolic acid and glycolate esters prepared according to this
procedure typically contained about 2 wt % ethylene glycol, 4 wt %
glycolic acid, 2 wt % glycolic acid dimer, 32 wt % glycolic acid
monoesters of ethylene glycol (23 wt % glycolic acid monomer ester
of EG, 8 wt % glycolic acid dimer monoester of EG, 2 wt % glycolic
acid trimer monoester of EG), and 60 wt % bis-glycolate esters of
EG (19 wt % glycolic acid monomer diester of EG, 11 wt % glycolic
acid dimer/glycolic acid monomer diester of EG, 4 wt % glycolic
acid trimer/glycolic acid monomer diester of EG, 30 wt % higher
glycolic acid oligomer diesters of EG). The above weight
percentages are shown for the components that were detected by GC
and do not represent all of the components present in the glycolic
acid/ester mixture because of the presence of higher molecular
weight oligomers of glycolic acid that do not elute leanly by gas
chromatography. These mixtures were used as the feed for glycolic
acid hydrogenation reaction as described in Example 2 below.
Example 1
Synthesis of Pentaerythrityl Trichlorohydrin (IX)
[0274] A five liter three neck round-bottom flask equipped with an
overheard stirrer, a condenser (with a nitrogen purge and a Vigreux
column to scrub off any sulfur dioxide), a "Y" connector, with a
thermocouple in one side and an addition funnel in the other, was
charged with 417 g (3.00 mol) of pentaerythritol and 730 g (9.24
mol) of pyridine. With vigorous stirring, 1134 g (9.24 mol) of
thionyl chloride was charged drop wise over a period of 3 hours and
45 minutes and the mixture was heated to 125.degree. C. and held at
125.degree. C. overnight. The brown-yellow solution was cooled to
room temperature and 2 L of cold, deionized water was charged with
stirring. The precipitate was filtered and washed with 2.5 L of
cold, deionized water. The vacuum-dried crude product, (459.7 g), a
1:3.1 mixture of pentaerythrityl trichlorohydrin (VIII) and
pentaerythrityltetrachloride (IX) as determined by NMR, was
separated using fractional distillation under reduced pressure and
recrystallized from cyclohexane to yield 253.5 g of (8). .sup.1H
NMR of 8 (CDCl.sup.3): .delta. 3.74 (s, 3H); 3.66 (s, 6H); 1.72
(br, 1H). .sup.13C{1H} NMR of 8 (CDCl.sup.3): .delta. 61.2, 46.7,
44.0 ppm.
Synthesis of 1-(3-Chloro-2,2-bis(chloromethyl)propoxy)butane
(X)
[0275] A 300 mL four neck round-bottom flask equipped with an
overheard stirrer, a condenser (with a nitrogen purge) and a
thermocouple was charged with 10 g (0.050 mol) of (VIII), 21.68 g
(0.16 mol) of 1-bromobutane and 52.50 mL of anhydrous DMSO. The
flask was cooled in an ice/water bath and 12.72 g (0.21 mol) of
finely ground KOH was charged with vigorous stirring. When no
further exotherm was observed, the reaction mixture was heated to
60.degree. C. for 3 hours with stirring. After cooling to room
temperature, 225 mL of deionized water was charged slowly. The
aqueous phase was extracted with dichloromethane (50 mL) four
times. The combined organic layers were washed with 250 mL of 2M
HCl, 2.times.150 mL of deionized water and then dried over
Na.sub.2SO.sub.4. After filtration, the solvent was removed using a
rotary evaporator. Product (X) was obtained as a faint yellow
liquid. Yield: 11.20 g (0.042 mol, 80%). .sup.1H NMR (CDCl.sub.3):
.delta. 3.65 (s, 6H); 3.46 (s, 2H); 3.44 (t, 2H); 1.56 (m, 2H);
1.36 (m, 2H); 0.92 (m, 3H). .sup.13C{1H} NMR (CDCl.sub.3): .delta.
71.4, 68.0, 46.2, 44.5, 31.6, 19.3, 13.8 ppm.
Synthesis of
(2-(butoxymethyl)-2-((diphenylphosphino)methyl)propane-1,3-diyl)bis(diphe-
nylphosphine) (IV)
[0276] A 500 mL three neck round-bottom flask containing 283 g
(0.30 mol) of a diethoxymethane (DEM) solution of lithium
diphenylphosphide was cooled to -78.degree. C. using a dry
ice/acetone bath. To this solution, 23.75 g (0.10 mol) of compound
(X) was charged over a period of 30 minutes with an Argon purge.
After all of compound (X) was charged, the acetone/dry ice bath was
removed, the mixture was allowed to warm to room temperature, and
stirred overnight. All volatiles were removed under vacuum, and the
residue was extracted with 50 mL of toluene two times. The extract
was washed with 50 mL of deionized water three times. The organic
phase was dried over Na.sub.2SO.sub.4, filtered, and the volatiles
were removed under vacuum. 49.5 g (about 74% crude yield and 92%
purity) of sticky solid was obtained after drying overnight under
vaccum. .sup.31P{1H} NMR (CDCl.sub.3): .delta. -26.3 ppm (s).
.sup.1H NMR (CDCl.sub.3): .delta. 7.50-7.34 (m, 30H); 3.29 (s, 2H);
2.85 (t, 2H); 2.71 (s, 6H); 1.24 m (5H); 0.90 (t, 3H). .sup.13C{1H}
NMR (CDCl.sub.3): .delta. 139.9 (d), 132.9 (d), 128.0 (s), 76.1
(q), 70.3 (s), 42.5 (q), 38.2 (m), 31.4 (s), 19.2 (s), 14.0 (s)
ppm.
Example 2
Hydrogenation of Glycolic Acid and Glycolate Esters
[0277] A mixture comprising 70 ml ethylene glycol, and 6 mL of the
glycolic acid/ester feed mixture described above, containing 5
weight percent water, and
(2-(butoxymethyl)-2-((diphenylphosphino)methyl)propane-1,3-diyl)bis(diphe-
nylphosphine) ruthenium diacetate (referred to herein as
"(BuO-triphos)Ru(OAc).sub.2") at a concentration of 100 ppm Ru
metal was loaded into a high pressure Hastelloy C autoclave. The
autoclave, nominally 100 mL volume, was fitted with a Rushton
turbine impeller, baffles, thermowell, and gas inlet tube. The
reactor vessel was heated electrically to 190.degree. C. by a band
heater, with temperature control provided by feedback via a K-type
thermocouple in the autoclave thermowell. Pure hydrogen gas
(>99.9 volume %) was fed to the autoclave via a Brooks flow
controller, with pressure maintained at 124.1 bars gauge (1800
psig). After the initial charge, a stock solution of the glycolic
acid/ester feed mixture described above containing 5 weight percent
water and (butoxy-triphos)Ru(OAc).sub.2, at a concentration of 100
ppm Ru metal was fed for five hours at a rate of 0.4 mL/min. After
five hours, the feed rate was cut to 0.197 mL/min (feed substrate
rate of 0.192 ml/min, and the catalyst rate of 0.005 mL/min).
Aliquots of reactor material were taken off every five minutes to
maintain the liquid level at approximately 71-72.5 mL. The
cumulative reactor effluent was found by GC analysis to comprise
85.23 weight percent ethylene glycol, 3.39 weight percent glycolate
mono esters of ethylene glycol, 4.5 weight percent water, 0.3
weight percent glycolic acid, and 0.5 weight percent glycolate
diesters of ethylene glycol. X-ray analysis showed the reactor
effluent to comprise 27.9 ppm Ru metal and 23.5 ppm phosphorus
content.
Example 3
[0278] This example illustrates the effect of water content in the
glycolic acid hydrogenation effluent feed mix and the effect of
hydrocarbon content of the extractant on extraction of ethylene
glycol, 1,2-butanediol (BDO), and 1,2-propanediol (PDO). In
Experiments 3-1 to 3-20, water was added to the reactor effluent
generated in Example 2 to give the water content specified in Table
1. In addition, 1 weight percent (on an undiluted reactor effluent
basis) each of BDO and PDO was added to the reaction effluent of
Example 2. The resulting mixtures were contacted (i.e., mixed
vigorously) with a solvent mixture comprising 2-ethylhexanol and
heptane in the composition and solvent to feed (S/F) ratio
specified in Table 1. Each mixture was held at 60.degree. C.,
allowed to separate into two clear phases and analyzed by GC to
determine EG, 1,2-PDO, 1,2-BDO weight percentages which were used
to calculate partition coefficients (P) of ethylene glycol,
1,2-BDO, and 1,2-PDO and selectivities between EG and the two other
diols. The ethylene glycol, 1,2-propanediol, and 1,2-butanediol
partition coefficients (abbreviated as P(EG), P(1,2-PDO), and
P(1,2-BDO)) and selectivities (abbreviated as S(1,2-PDO/EG), and
S(1,2-BDO/EG)) are summarized in Table 1.
TABLE-US-00003 TABLE 1 Wt % Wt % S/F Water in Heptane in Ex. Ratio
Feed Mix Solvent Mix P(EG) P(1,2-PDO) P(1,2-BDO) S(1,2-PDO/EG)
S(1,2-BDO/EG) 3-1 0.99 9.89% 0.0% 0.46 0.63 0.87 1.37 1.89 3-2 1.00
14.00% 0.0% 0.31 0.50 0.79 1.61 2.55 3-3 0.99 23.71% 0.0% 0.21 0.37
0.68 1.76 3.24 3-4 1.00 33.25% 0.0% 0.16 0.31 0.63 1.94 3.94 3-5
1.00 9.89% 10.0% 0.32 0.48 0.72 1.50 2.25 3-6 0.99 14.00% 10.0%
0.23 0.39 0.65 1.70 2.83 3-7 1.01 23.71% 10.0% 0.16 0.31 0.58 1.94
3.63 3-8 1.00 33.25% 10.0% 0.12 0.25 0.53 2.08 4.42 3-9 1.00 9.89%
15.1% 0.26 0.41 0.64 1.58 2.46 3-10 1.01 14.00% 15.1% 0.20 0.35
0.58 1.75 2.90 3-11 1.00 23.71% 15.1% 0.14 0.27 0.53 1.93 3.79 3-12
1.00 33.25% 15.1% 0.11 0.23 0.48 2.09 4.36 3-13 1.00 9.89% 20.0%
0.22 0.36 0.58 1.64 2.64 3-14 0.99 14.00% 20.0% 0.18 0.31 0.54 1.72
3.00 3-15 1.01 23.71% 20.0% 0.13 0.25 0.49 1.92 3.77 3-16 0.99
33.25% 20.0% 0.10 0.21 0.45 2.10 4.50 3-17 0.99 9.89% 30.0% 0.16
0.27 0.45 1.69 2.81 3-18 1.00 14.00% 30.0% 0.14 0.25 0.45 1.79 3.21
3-19 1.00 23.71% 30.0% 0.10 0.20 0.39 2.00 3.90 3-20 1.00 33.25%
30.0% 0.08 0.17 0.37 2.13 4.63
Example 4
[0279] A standard ethylene-glycol rich solution was prepared
comprising 90 weight percent ethylene glycol (EG), and five weight
percent each of 1,2-propanediol (1,2-PDO) and 1,2-butanediol
(1,2-BDO). Five grams of this standard solution was added to a
separate glass vial along with five grams of each of the nonpolar
solvents listed in Table 2. The contents were mixed vigorously and
allowed to settle and separate into two clear phases. The phases
were analyzed by gas chromatography to determine EG, 1,2-PDO,
1,2-BDO weight percentages. These analytical results were used to
calculate partition coefficients and selectivities. All experiments
were conducted at room temperature. Results are summarized in Table
2.
TABLE-US-00004 TABLE 2 P(1,2- P(1,2- S(1,2- S(1,2- Ex Solvent P(EG)
PDO) BDO) PDO/EG) BDO/EG) 4-1 EA 0.16 0.22 0.30 1.33 1.86 4-2 NBA
0.04 0.06 0.11 1.71 3.01 4-3 IBA 0.03 0.06 0.10 1.75 3.10 4-4 IPA
0.06 0.10 0.16 1.54 2.47 4-5 IBIB 0.01 0.02 0.05 2.13 4.23 4-6 EHA
0.01 0.02 0.04 2.10 4.58 4-7 EP 0.05 0.08 0.13 1.62 2.72 4-8 MV
0.03 0.05 0.09 1.70 2.96 4-9 NPP 0.03 0.05 0.09 1.83 3.28 4-10 MP
0.10 0.14 0.22 1.44 2.16 4-11 MB 0.04 0.07 0.12 1.65 2.82 4-12 5E2N
0.02 0.12 0.11 7.08 6.57 4-13 MAK 0.07 0.10 0.17 1.50 2.49 4-14
DIBK 0.02 0.03 0.12 1.60 5.96 4-15 MIPK 0.34 0.41 0.50 1.21 1.49
4-16 MIAK 0.07 0.11 0.17 1.52 2.48 4-17 TXIB 0.01 0.02 0.03 1.53
2.90 4-18 MIBK 0.10 0.15 0.23 1.45 2.21 4-19 MTBE 0.05 0.08 0.15
1.74 3.15 4-20 DIPE 0.01 0.02 0.04 1.66 3.27 4-21 DBE 0.01 0.01
0.01 1.21 2.56 4-22 DEGDBE 0.03 0.05 0.09 1.54 2.86 4-23 TOL 0.00
0.00 0.01 0.62 1.26 4-24 MPK 0.40 0.47 0.57 1.18 1.42
Example 5
[0280] Water was added to the standard ethylene-glycol rich
solution prepared for Example 4, comprising 90 weight percent
ethylene glycol (EG), and five weight percent each of
1,2-propanediol (1,2-PDO) and 1,2-butanediol (1,2-BDO). The amount
of water on a total solution basis was 10 weight percent (i.e.,
based on the total weight of diols and water). Five grams of this
water-containing solution was added to a separate glass vial along
with five grams of each of the nonpolar solvents listed in Table 3.
The contents were mixed vigorously and allowed to settle and
separate into two clear phases. The phases were analyzed by gas
chromatography to determine EG, 1,2-PDO, 1,2-BDO weight
percentages. These analytical results were used to calculate
partition coefficients and selectivities. All experiments were
conducted at room temperature. Results are summarized in Table
3.
TABLE-US-00005 TABLE 3 P(1,2- P(1,2- S(1,2- S(1,2- Ex Solvent P(EG)
PDO) BDO) PDO/EG) BDO/EG) 5-1 NH 1.09 0.51 1.03 0.47 0.95 5-2 2-EH
0.37 0.51 0.79 1.39 2.15 5-3 CH 0.67 0.80 1.12 1.19 1.67 5-4 EA
0.10 0.15 0.24 1.45 2.33 5-5 NBA 0.03 0.05 0.10 1.87 3.68 5-6 IBA
0.03 0.05 0.09 1.84 3.76 5-7 IPA 0.05 0.08 0.14 1.71 3.12 5-8 NPA
0.01 0.02 0.04 2.19 4.77 5-9 IBIB 0.01 0.02 0.04 2.28 5.25 5-10 EHA
0.03 0.06 0.12 1.83 3.51 5-11 EP 0.02 0.04 0.08 1.93 4.15 5-12 MV
0.02 0.04 0.08 2.01 4.08 5-13 NPP 0.07 0.10 0.18 1.58 2.77 5-14 MP
0.03 0.06 0.11 1.85 3.50 5-15 MB 0.02 0.03 0.09 1.75 5.45 5-16 5E2N
0.04 0.07 0.15 1.68 3.33 5-17 MAK 0.02 0.03 0.12 1.66 7.39 5-18
DIBK 0.16 0.22 0.34 1.42 2.15 5-19 MIPK 0.05 0.08 0.15 1.70 3.26
5-20 MIAK 0.01 0.02 0.03 1.52 3.41 5-21 TXIB 0.06 0.11 0.19 1.64
2.95 5-22 MIBK 0.23 0.33 0.55 1.42 2.37 5-23 IPH 0.04 0.07 0.14
1.80 3.63 5-24 MTBE 0.01 0.02 0.04 1.56 3.43 5-25 DIPE 0.01 0.01
0.02 0.95 2.51 5-26 DBE 0.03 0.04 0.09 1.61 3.38 5-27 DEGDBE 0.00
0.00 0.01 0.58 1.56 5-28 TOL 0.00 0.00 0.01 0.57 1.46 5-29 PC 3.02
2.74 2.24 0.91 0.74 5-30 MPK 0.18 0.25 0.38 1.39 2.09
Example 6
[0281] This example illustrates the effect of increased water
content on the partition coefficients and selectivities of diols. A
standard ethylene-glycol rich solution was prepared comprising 74.8
weight percent ethylene glycol (EG), 15 weight percent water, and
1.7 weight percent each of 1,2-propanediol (1,2-PDO),
1,2-butanediol (1,2-BDO), 1,3-propanediol (1,3-PDO), 2,3-butanediol
(2,3-BDO), 1,3-butanediol (1,3-BDO), and 1,4-butanediol (1,4-BDO).
Ten grams of this standard solution were added to a separate glass
vial along with ten grams of each of the hydrophobic solvent
mixtures listed in Table 4a. The contents were mixed vigorously and
allowed to settle and separate into two clear phases and analyzed
by gas chromatography to determine weight percentages of each of
the diols. These analytical results were used to calculate
partition coefficients (Table 4b) and selectivities (Table 4c). All
experiments were conducted at 60 degrees Celsius.
TABLE-US-00006 TABLE 4a Hydrophobic Hydrophobic Wt % Wt % Ex
Solvent 1 Solvent 2 Solvent 1 Solvent 2 6-1 EA -- 100% 0% 6-2 DIBK
-- 100% 0% 6-3 MIBK -- 100% 0% 6-4 2-EH -- 100% 0% 6-5 2-EH HEP 90%
10% 6-6 2-EH HEP 80% 20% 6-7 ND -- 100% 0% 6-8 ND HEP 90% 10% 6-9
ND HEP 80% 20%
TABLE-US-00007 TABLE 4b P(1,2- P(2,3- P(1,3- P(1,2- P(1,3- P(1,4-
Ex P(EG) PDO) BDO) PDO) BDO) BDO) BDO) 6-1 0.18 0.27 0.44 0.19 0.41
0.30 0.23 6-2 0.13 0.23 0.40 0.15 0.38 0.26 0.19 6-3 0.02 0.04 0.29
0.03 0.19 0.06 0.04 6-4 0.02 0.03 0.31 0.03 0.22 0.05 0.04 6-5 0.11
0.18 0.34 0.13 0.31 0.22 0.16 6-6 0.07 0.13 0.28 0.09 0.28 0.17
0.12 6-7 0.37 0.53 0.76 0.47 0.79 0.62 0.52 6-8 0.18 0.34 0.62 0.31
0.66 0.44 0.34 6-9 0.25 0.39 0.67 0.34 0.66 0.47 0.37
TABLE-US-00008 TABLE 4c S(1,2- S(2,3- S(1,3- S(1,2- S(1,3- S(1,4-
PDO/ BDO/ PDO/ BDO/ BDO/ BDO/ Ex EG) EG) EG) EG) EG) EG) 6-1 1.51
2.42 1.07 2.25 1.65 1.25 6-2 1.73 3.06 1.15 2.94 1.95 1.45 6-3 1.70
12.15 1.27 7.99 2.56 1.78 6-4 1.85 16.84 1.45 11.75 2.92 2.30 6-5
1.70 3.15 1.18 2.90 2.06 1.44 6-6 2.00 4.21 1.31 4.16 2.59 1.83 6-7
1.45 2.07 1.29 2.16 1.68 1.42 6-8 1.86 3.41 1.73 3.67 2.42 1.88 6-9
1.60 2.71 1.39 2.66 1.92 1.52
Example 7
[0282] This example illustrates the effect of increased water
content on the partition coefficients and selectivities of diols. A
standard ethylene-glycol rich solution was prepared comprising 61.6
weight percent ethylene glycol (EG), 30 weight percent water, and
1.4 weight percent each of 1,2-propanediol (1,2-PDO),
1,2-butanediol (1,2-BDO), 1,3-propanediol (1,3-PDO), 2,3-butanediol
(2,3-BDO), 1,3-butanediol (1,3-BDO), and 1,4-butanediol (1,4-BDO).
Ten grams of this standard solution were added to a separate glass
vial along with ten grams of each of the hydrophobic solvent
mixtures listed in Table 5a. The contents were mixed vigorously and
allowed to settle and separate into two clear phases and analyzed
by gas chromatography to determine weight percentages of each of
the diols. These analytical results were used to calculate
partition coefficients (Table 5b) and selectivities (Table 5c). All
experiments were conducted at 60 degrees Celsius.
TABLE-US-00009 TABLE 5a Hydrophobic Hydrophobic Wt % Wt % Ex
Solvent 1 Solvent 2 Solvent 1 Solvent 2 7-1 EA -- 100% 0% 7-2 DIBK
-- 100% 0% 7-3 MIBK -- 100% 0% 7-4 2-EH -- 100% 0% 7-5 2-EH HEP 90%
10% 7-6 2-EH HEP 80% 20% 7-7 ND -- 100% 0% 7-8 ND HEP 90% 10% 7-9
ND HEP 80% 20%
TABLE-US-00010 TABLE 5b P(1,2- P(2,3- P(1,3- P(1,2- P(1,3- P(1,4-
Ex P(EG) PDO) BDO) PDO) BDO) BDO) BDO) 7-1 0.14 0.27 0.51 0.25 0.55
0.35 0.70 7-2 0.18 0.30 0.54 0.25 0.52 0.36 0.27 7-3 0.11 0.21 0.43
0.20 0.46 0.28 0.20 7-4 0.28 0.42 0.65 0.31 0.68 0.48 0.38 7-5 0.15
0.26 0.50 0.18 0.55 0.34 0.26 7-6 0.20 0.32 0.55 0.22 0.55 0.37
0.29 7-7 0.12 0.23 0.45 0.15 0.48 0.29 0.22 7-8 0.15 0.26 0.47 0.17
0.47 0.31 0.23 7-9 0.10 0.18 0.38 0.12 0.41 0.24 0.17
TABLE-US-00011 TABLE 5c S(1,2- S(2,3- S(1,3- S(1,2- S(1,3- S(1,4-
PDO/ BDO/ PDO/ BDO/ BDO/ BDO/ Ex EG) EG) EG) EG) EG) EG) 7-1 1.92
3.69 1.80 3.97 2.51 5.02 7-2 1.69 3.07 1.44 2.95 2.03 1.53 7-3 2.00
3.98 1.87 4.25 2.58 1.89 7-4 1.51 2.34 1.11 2.46 1.74 1.38 7-5 1.77
3.32 1.22 3.65 2.27 1.73 7-6 1.59 2.79 1.12 2.78 1.88 1.44 7-7 1.83
3.59 1.22 3.90 2.36 1.81 7-8 1.67 3.06 1.12 3.05 1.98 1.46 7-9 1.91
3.92 1.22 4.24 2.48 1.80
Example 8
[0283] This example illustrates the back extraction of three-carbon
diols and four-carbon diols from a hydrophobic solvent mixture
using water. Hydrophobic solvent and diol mixtures were prepared
from 2-EH, HEP, EG, 1,2-PDO, 1,2-BDO, 1,3-PDO, 2,3-BDO, 1,3-BDO,
and 1,4-BDO. Ten grams of water were added to a separate glass vial
along with fifteen grams of each of the hydrophobic solvent mixture
as listed in Table 6a. The contents were mixed vigorously and
allowed to settle and separate into two clear phases and analyzed
by gas chromatography to determine weight percentages of each of
the diols. These analytical results were used to calculate
partition coefficients (Table 6b) and selectivities (Table 6c). All
experiments were conducted at 60 degrees Celsius.
TABLE-US-00012 TABLE 6a 1,2- 1,2- 1,3- 1,3- 1,4- 2,3- 2-EH, HEP,
PDO, BDO, PDO, BDO, BDO, BDO, EG, Ex wt % wt % wt % wt % wt % wt %
wt % wt % wt % 8-1 84.6% 9.4% 2.0% 2.0% 0.0% 0.0% 0.0% 0.0% 2.0%
8-2 75.2% 18.8% 2.0% 2.0% 0.0% 0.0% 0.0% 0.0% 2.0% 8-3 65.8% 28.2%
2.0% 2.0% 0.0% 0.0% 0.0% 0.0% 2.0% 8-4 56.4% 37.6% 2.0% 2.0% 0.0%
0.0% 0.0% 0.0% 2.0% 8-5 77.4% 8.6% 2.0% 2.0% 2.0% 2.0% 2.0% 2.0%
2.0% 8-6 68.8% 17.2% 2.0% 2.0% 2.0% 2.0% 2.0% 2.0% 2.0% 8-7 60.2%
25.8% 2.0% 2.0% 2.0% 2.0% 2.0% 2.0% 2.0% 8-8 51.6% 34.4% 2.0% 2.0%
2.0% 2.0% 2.0% 2.0% 2.0%
TABLE-US-00013 TABLE 6b P(1,2- P(1,2- P(1,3- P(1,3- P(1,4- P(2,3-
Ex PDO) BDO) PDO) BDO) BDO) BDO) P(EG) 8-1 0.087 0.28 N/A N/A N/A
N/A 0.035 8-2 0.075 0.24 N/A N/A N/A N/A 0.030 8-3 0.061 0.20 N/A
N/A N/A N/A 0.025 8-4 0.050 0.17 N/A N/A N/A N/A 0.020 8-5 0.101
0.31 0.11 0.17 0.13 0.19 0.043 8-6 0.082 0.26 0.09 0.13 0.10 0.16
0.034 8-7 0.069 0.22 0.08 0.11 0.08 0.13 0.028 8-8 0.056 0.18 0.06
0.09 0.06 0.11 0.022
TABLE-US-00014 TABLE 6c S(1,2- S(1,2- S(1,3- S(1,3- S(1,4- S(2,3-
PDO/ BDO/ PDO/ BDO/ BDO/ BDO/ Ex EG) EG) EG) EG) EG) EG) 8-1 2.47
8.00 N/A N/A N/A N/A 8-2 2.50 8.11 N/A N/A N/A N/A 8-3 2.49 8.15
N/A N/A N/A N/A 8-4 2.57 8.55 N/A N/A N/A N/A 8-5 2.34 7.09 2.63
3.85 3.01 4.34 8-6 2.43 7.57 2.72 3.91 2.98 4.58 8-7 2.48 7.84 2.76
3.89 2.87 4.73 8-8 2.51 7.89 2.71 3.80 2.72 4.79
Example 9
[0284] This example illustrates a second back extraction of diols
from a hydrophobic solvent mixture using water. The hydrophobic top
phases from examples 8-1 through 8-8 were further contacted with a
second aliquot of water. Ten grams of water were added to a
separate glass vial along with each of the hydrophobic top phases
from examples 8-1 to 8-8 (typically about 13 grams). The contents
were mixed vigorously and allowed to settle and separate into two
clear phases and analyzed by gas chromatography to determine weight
percentages of each of the diols. These analytical results were
used to calculate partition coefficients (Table 7a) and
selectivities (Table 7b). In examples 9-3 through 9-8, no EG was
remaining in the top layers from the first extractions of examples
8-3 through 8-8, so EG-based selectivities could not be calculated.
All experiments were conducted at 60 degrees Celsius.
TABLE-US-00015 TABLE 7a P(1,2- P(1,2- P(1,3- P(1,3- P(1,4- P(2,3-
Ex PDO) BDO) PDO) BDO) BDO) BDO) P(EG) 9-1 0.149 0.39 N/A N/A N/A
N/A 0.051 9-2 0.120 0.31 N/A N/A N/A N/A 0.038 9-3 0.115 0.27 N/A
N/A N/A N/A Not detect 9-4 0.099 0.22 N/A N/A N/A N/A Not detect
9-5 0.157 0.40 0.56 0.21 0.17 0.26 Not detect 9-6 0.136 0.33 0.59
0.17 0.13 0.21 Not detect 8-7 0.116 0.27 0.62 0.14 0.11 0.18 Not
detect 9-8 0.105 0.22 0.64 0.11 0.09 0.14 Not detect
TABLE-US-00016 TABLE 7b S(1,2- S(1,2- S(1,3- S(1,3- S(1,4- S(2,3-
PDO/ BDO/ PDO/ BDO/ BDO/ BDO/ Ex EG) EG) EG) EG) EG) EG) 9-1 2.90
7.52 N/A N/A N/A N/A 9-2 3.18 8.19 N/A N/A N/A N/A 9-3 N/A N/A N/A
N/A N/A N/A 9-4 N/A N/A N/A N/A N/A N/A 9-5 N/A N/A N/A N/A N/A N/A
9-6 N/A N/A N/A N/A N/A N/A 8-7 N/A N/A N/A N/A N/A N/A 9-8 N/A N/A
N/A N/A N/A N/A
Example 10
[0285] A mixed diol solution was prepared by mixing 1.5 weight
percent each of 1,2-propanediol (1,2-PDO) and 1,2-butanediol
(1,2-BDO), with the remainder ethylene glycol (EG). Three standard
water-diol solutions were prepared by mixing 0 weight percent, 10
weight percent, or 20 weight percent water with the above mixed
diol solution, based on the total weight of diol and water. Four
standard non-polar solutions were prepared comprising either 1
weight percent, 10 weight percent, 30 weight percent, or 50 weight
percent Cyanex.RTM. 923 solvent (C923), with the remainder heptane.
Another four standard non-polar solutions were prepared comprising
either 1 weight percent, 10 weight percent, 30 weight percent, or
50 weight percent C923 solvent, with the remainder toluene. Ten
grams of each of the standard ethylene glycol rich solutions were
contacted with ten grams of each of the eight Cyanex standard
solutions in separate glass vials. The contents were mixed
vigorously and allowed to settle and separate into two clear
phases. The phases were analyzed by gas chromatography to determine
weight percentages of each of the diols in each phase. These
analytical results were used to calculate partition coefficients
for EG, 1,2-PDO, and 1,2-BDO as shown in Tables 8a, 8b, and 8c
respectively. Selectivities over EG are given in Table 8d and Table
8e for 1,2-PDO and 1,2-BDO, respectively. All experiments were
conducted at room temperature.
TABLE-US-00017 TABLE 8a wt % C923 in P(EG) w/0% P(EG) w/10% P(EG)
w/20% Cosol- solvent H2O in Diol H2O in Diol H2O in Diol Ex vent
mixture Mixture Mixture Mixture 10-1 Heptane 1.0% 0.0016 0.0016
0.0013 10-2 Heptane 10.0% 0.0182 0.0169 0.0157 10-3 Heptane 30.0%
0.0667 0.0614 0.0554 10-4 Heptane 50.0% 0.1268 0.1138 0.1016 10-5
Toluene 1.0% 0.0046 0.0036 0.0033 10-6 Toluene 10.0% 0.0342 0.0229
0.0205 10-7 Toluene 30.0% 0.0917 0.0757 0.0662 10-8 Toluene 50.0%
0.1575 0.1282 0.1177
TABLE-US-00018 TABLE 8b wt % P(1,2-PDO) P(1,2-PDO) P(1,2-PDO) C923
in w/0% H2O w/10% H2O w/20% H2O Cosol- solvent in Diol in Diol in
Diol Ex vent mixture Mixture Mixture Mixture 10-1 Heptane 1.0%
0.0034 0.0032 0.0070 10-2 Heptane 10.0% 0.0400 0.0402 0.0351 10-3
Heptane 30.0% 0.1275 0.1282 0.1235 10-4 Heptane 50.0% 0.2241 0.2207
0.2118 10-5 Toluene 1.0% 0.0100 0.0080 0.0088 10-6 Toluene 10.0%
0.0632 0.0486 0.0440 10-7 Toluene 30.0% 0.1581 0.1452 0.1367 10-8
Toluene 50.0% 0.2550 0.2298 0.2286
TABLE-US-00019 TABLE 8c wt % P(1,2-BDO) P(1,2-BDO) P(1,2-BDO) C923
in w/0% H2O w/10% H2O w/20% H2O Cosol- solvent in Diol in Diol in
Diol Ex vent mixture Mixture Mixture Mixture 10-1 Heptane 1.0%
0.0134 0.0101 0.0211 10-2 Heptane 10.0% 0.0879 0.0986 0.1054 10-3
Heptane 30.0% 0.2601 0.2966 0.3235 10-4 Heptane 50.0% 0.4432 0.4955
0.5301 10-5 Toluene 1.0% 0.0208 0.0203 0.0000 10-6 Toluene 10.0%
0.1218 0.1117 0.1194 10-7 Toluene 30.0% 0.2989 0.3130 0.3341 10-8
Toluene 50.0% 0.4659 0.4812 0.5448
TABLE-US-00020 TABLE 8d wt % S(1,2-PDO/ S(1,2-PDO/ S(1,2-PDO/ C923
in EG) w/0% EG) w/10% EG) w/20% Cosol- solvent H2O in Diol H2O in
Diol H2O in Diol Ex vent mixture Mixture Mixture Mixture 10-1
Heptane 1.0% 2.09 2.06 5.27 10-2 Heptane 10.0% 2.20 2.37 2.24 10-3
Heptane 30.0% 1.91 2.09 2.23 10-4 Heptane 50.0% 1.77 1.94 2.08 10-5
Toluene 1.0% 2.18 2.23 3.03 10-6 Toluene 10.0% 1.84 2.12 2.63 10-7
Toluene 30.0% 1.72 1.92 2.06 10-8 Toluene 50.0% 1.62 1.79 1.94
TABLE-US-00021 TABLE 8e wt % S(1,2-BDO/ S(1,2-BDO/ S(1,2-BDO/ C923
in EG) w/0% EG) w/10% EG) w/20% Cosol- solvent H2O in Diol H2O in
Diol H2O in Diol Ex vent mixture Mixture Mixture Mixture 10-1
Heptane 1.0% 8.15 6.45 15.83 10-2 Heptane 10.0% 4.83 5.82 6.73 10-3
Heptane 30.0% 3.90 4.83 5.84 10-4 Heptane 50.0% 3.49 4.35 5.22 10-5
Toluene 1.0% 4.53 5.66 7.13 10-6 Toluene 10.0% 3.56 4.87 5.83 10-7
Toluene 30.0% 3.26 4.13 5.05 10-8 Toluene 50.0% 2.96 3.75 4.63
Example 11
[0286] An ethylene glycol-rich solution was prepared by mixing 95
weight percent ethylene glycol, and 2.5 weight percent each of
1,2-propanediol and 1,2-butanediol. The resulting mixed diol feed
was subjected to a cascaded series of twenty-four cross-flow batch
extractions to simulate a six-stage continuous counter-current
fractional extraction process, with the mixed diol feed introduced
on stage four (from the bottom), the hydrophobic solvent,
2-ethylhexanol (2-EH), introduced on stage one (from bottom), and
the water wash on stage six (top of extractor). The multi-cycle,
cascaded pattern of 24 extractions in which one mixed diol feed
charge is added into the center of the first cycle of the cascade,
and multiple hydrophobic solvent and water wash charges are
introduced at separate ends of each cycle of the cascade, and with
raffinate and extract compositions introduced to the next cycle of
the cascade, results in a set of conditions on the final cycle
which have been shown to closely approach the equilibrium
composition profile of a continuous, staged, counter-current
fractional extractor. For this work, three cycles were found to be
sufficient to asymptotically approach continuous extraction
equilibrium conditions. The simulated counter-current extraction
technique used herein is well-known to those skilled in the art and
is laid out in detail in Treybal ("Liquid Extraction," 2nd Ed.,
McGraw-Hill Book Company, New York, N.Y., 1963, pp. 349-366). The
water to mixed diol feed weight ratio was 0.4:1.0, and the 2-EH to
mixed diol feed ratio was 1.5:1.0. The experiment was conducted at
room temperature. The final simulated extract (top product) and
raffinate (bottom product) streams were subjected to gas
chromatography to determine the compositions of the products.
Results are given in Table 9. The percent recovery to the extract
is based on the amount of each component in all inputs to the
extractor. The solvent free raffinate composition (in weight
percent) is calculated based on the total weight of EG, 1,2-PDO,
and 1,4-BDO in the raffinate.
TABLE-US-00022 TABLE 9 Feed Extract Raffinate Composition
Composition % Composition Solvent Free of Feed, Wt of Extract,
Recovery of Raffinate, Composition, % Wt % to Extract Wt % Wt % EG
95.0% 0.26% 0.4% 69.56% 97.0% 1,2-BDO 2.5% 1.04% 64.0% 0.66% 0.9%
1,2-PDO 2.5% 0.32% 20.0% 1.47% 2.1% Water 2.73% 10.0% 26.32% 2-EH
95.65% 98.2% 1.99%
Example 12
[0287] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
95 weight percent EG, 2.5 weight percent 1,2-PDO, and 2.5 weight
percent 1,2-BDO. The extractant for the fractional extraction
contains 99.1 weight percent 2-ethylhexanol and 0.9 weight percent
water. The column comprises fifteen theoretical stages. The mixed
diol feed is fed on stage ten (from the bottom), the extractant, is
introduced on stage one (from bottom), and the water wash on stage
15. The water to mixed diol feed weight ratio is 0.53:1.0, and the
extractant to mixed diol feed ratio is 4.5:1.0. The system was
modeled using the Kremser method, as described in Treybal, Liquid
Extraction, 2.sup.nd Ed., McGraw Hill Book Company, 1963, pp.
248-252, with partition coefficients correlated from the data of
Examples 3 and 6. Material balance (all values in kg/hr) data are
given in Table 10. Recovery of 1,2-BDO to the extract product is
98.0 weight percent. Recovery of EG to the raffinate is 99.95
weight percent.
TABLE-US-00023 TABLE 10 1,2- 1,2- Stream ID EG PDO BDO Water 2-EH
Total Mixed Diol 95 2.5 2.5 100.0 Feed Extractant 5.0 450.0 455.0
Water Wash 53.0 53.0 TOTAL IN 95 2.5 2.5 58.0 450.0 608.0 Extract
0.04 0.33 2.45 6.0 447.4 456.22 Raffinate 94.96 2.17 0.05 52.0 2.6
151.78 TOTAL OUT 95 2.5 2.5 58.0 450.0 608.0
Example 13
[0288] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
95 weight percent EG, 2.5 weight percent 1,2-PDO, and 2.5 weight
percent 1,2-BDO. The extractant for the fractional extraction
contains 80 weight percent Cyanex.RTM. 923 and 20 weight percent
heptane. The column comprises fifteen theoretical stages. The mixed
diol feed is fed on stage ten (from the bottom), the extractant is
introduced on stage one (from bottom), and the water wash on stage
15. The water to mixed diol feed weight ratio is 0.57:1.0, and the
extractant to mixed diol feed ratio is 2.0:1.0. The system was
modeled using the Kremser method, as described in Treybal, Liquid
Extraction, 2.sup.nd Ed., McGraw Hill Book Company, 1963, pp.
248-252, with partition coefficients correlated from the data of
Example 10. Material balance (all values in kg/hr) data are given
in Table 11. Recovery of 1,2-BDO to the extract product is 99.7
weight percent. Recovery of EG to the raffinate is 99.95 weight
percent.
TABLE-US-00024 TABLE 11 1,2- 1,2- Wa- Stream ID EG PDO BDO ter C923
HEP Total Mixed Diol 95 2.5 2.5 100.0 Feed Extractant 160.0 40.0
200.0 Water Wash 57.0 57.0 TOTAL IN 95 2.5 2.5 57.0 160.0 40.0
357.0 Extract 0.05 0.12 2.49 17.8 159.99 40.0 220.45 Raffinate
94.95 2.38 0.01 39.2 0.01 0.0 136.55 TOTAL OUT 95 2.5 2.5 57.0
160.0 40.0 357.0
Example 14
[0289] This example illustrates a computer-generated material
balance for the fractional distillation of a mixed diol feed
comprising 99.785 weight percent EG, 0.097 weight percent 1,2-PDO
(970 ppm by weight), and 0.118 weight percent 1,2-BDO (1180 ppm by
weight), derived for example, from the hydrogenation of glycolic
acid species. One hundred kg/hr of a mixed diol feed is fed to the
eighteenth stage of a distillation column comprising thirty-six
theoretical stages (numbered from the top down), a reboiler, and a
condenser. The column is operated at 0.2 bar absolute and the
reflux ratio and reboiler heat duty is varied to achieve 80 ppm by
mass of 1,2-PDO and 1,2-BDO combined in the EG underflow product.
Results are given in Table 12.
TABLE-US-00025 TABLE 12 Heat Exam- Reflux Duty, 1,2- 1,2- ple Ratio
MJ/hr EG PDO BDO F, Kg/hr 99.785 0.097 0.118 14-1 204.3 352.1 D,
Kg/hr 1.701 0.095 0.112 B, Kg/hr 98.084 0.002 0.006 B Purity
99.992% 16 ppm 64 ppm 14-2 480.7 403.4 D, Kg/hr 0.75 0.096 0.111 B,
Kg/hr 99.035 0.001 0.007 B Purity 99.992% 13 ppm 67 ppm 14-3
5432.11 1686.5 D, Kg/hr 0.179 0.097 0.11 B, Kg/hr 99.606 0 0.008 B
Purity 99.992% 5 ppm 75 ppm
Example 15
[0290] This example illustrates a computer-generated material
balance for the pre-distillation of a mixed diol feed comprising
99.785 weight percent EG, 0.097 weight percent 1,2-PDO (970 ppm by
weight), and 0.118 weight percent 1,2-BDO (1180 ppm by weight),
derived for example, from the hydrogenation of glycolic acid
species. One hundred kg/hr of a mixed diol feed is fed to the
eighteenth stage of a distillation column comprising thirty-six
theoretical stages (numbered from the top down), a reboiler, and a
condenser. The column is operated at 0.2 bar absolute in the
distillate at a mass reflux ratio of 1086:1. Heat duty in the
reboiler is calculated as 329 MJ/hr. Material balance (all values
in kg/hr) data are given in Table 13. Recovery of 1,2-BDO and
1,2-PDO to the distillate product are 70 weight percent and 95
weight percent, respectively. Recovery of EG to the bottoms product
is 99.8 weight percent. The purified EG bottoms product consists of
49 ppm by weight 1,2-PDO, 347 ppm by weight of 1,2-BDO, and the
remainder EG.
TABLE-US-00026 TABLE 13 Bottoms Distillate Feed EG 99.592 0.193
99.785 1,2-PDO 0.005 0.092 0.097 1,2-BDO 0.035 0.083 0.118
Example 16
[0291] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
99.96 weight percent EG, 49 ppm by weight 1,2-PDO, and 347 ppm by
weight 1,2-BDO. This composition is the same as the bottoms product
of the distillation step described in Example 15. The extractant
for the fractional extraction contains 99.1 weight percent
2-ethylhexanol and 0.9 weight percent water. The column comprises
fifteen theoretical stages. The mixed diol feed is fed on stage ten
(from the bottom), the extractant is introduced on stage one (from
bottom), and the water wash on stage 15. The water wash to mixed
diol feed weight ratio is 0.16:1.0, and the extractant to mixed
diol feed ratio is 2.5:1.0. The system was modeled using the
Kremser method, as described in Treybal, Liquid Extraction,
2.sup.nd Ed., McGraw Hill Book Company, 1963, pp. 248-252, with
partition coefficients correlated from the data of Examples 3 and
6. Material balance (all values in kg/hr) data are given in Table
14. Recovery of 1,2-BDO to the extract product is 89.6 weight
percent. Recovery of EG to the raffinate is 99.99 weight percent.
The EG product on a solvent-free and water-free basis comprises 36
ppm by weight 1,2-BDO, 42 ppm by weight of 1,2-PDO, and the
remainder EG.
TABLE-US-00027 TABLE 14 1,2- 1,2- Stream ID EG PDO BDO Water 2-EH
Total Mixed Diol 99.59 0.00500 0.03500 99.632 Feed Extractant 2.29
249.08 251.38 Water Wash 15.76 15.76 TOTAL IN 99.59 0.01 0.04 18.05
249.08 366.77 Extract 0.0163 0.00078 0.03139 1.00 235.09 236.15
Raffinate 99.58 0.00422 0.00363 17.05 13.99 130.62 TOTAL OUT 99.59
0.00 0.04 18.05 249.08 366.77
Example 17
[0292] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
99.96 weight percent EG, 49 ppm by weight 1,2-PDO, and 347 ppm by
weight 1,2-BDO. This composition is the same as the bottoms product
of the distillation step described in Example 15. The extractant
for the fractional extraction contains 80 weight percent
Cyanex.RTM. 923 and 20 weight percent decane. The column comprises
fifteen theoretical stages. The mixed diol feed is fed on stage ten
(from the bottom), the extractant, is introduced on stage one (from
bottom), and the water wash on stage 15. The water wash to mixed
diol feed weight ratio is 0.36:1.0, and the extractant to mixed
diol feed ratio is 1.35:1.0. The system was modeled using the
Kremser method, as described in Treybal, Liquid Extraction,
2.sup.nd Ed., McGraw Hill Book Company, 1963, pp. 248-252, with
partition coefficients correlated from the data of Example 10
(i.e., the partition coefficients calculated from the 80 weight
percent Cyanex.RTM. 923 and 20 weight percent heptane extractant
are used). Material balance (all values in kg/hr) data are given in
Table 15. Recovery of 1,2-BDO to the extract product is 90.4 weight
percent. Recovery of EG to the raffinate is 99.72 weight percent.
The EG product on a solvent-free and water-free basis comprises 34
ppm by weight 1,2-BDO, 48 ppm by weight of 1,2-PDO, and the
remainder EG.
TABLE-US-00028 TABLE 15 Stream ID EG 1,2-PDO 1,2-BDO Water C923
Decane Total Mixed Diol 99.59 0.00500 0.03500 99.632 Feed
Extractant 107.60 26.90 134.50 Water Wash 40.82 37.17 TOTAL IN
99.59 0.01 0.04 40.82 107.60 26.90 274.96 Extract 0.2746 0.00018
0.03163 11.96 107.59 26.90 146.76 Raffinate 99.32 0.00482 0.00336
28.86 0.01 0.00 128.20 TOTAL OUT 99.59 0.00 0.03 40.82 107.60 26.90
274.96
Example 18
[0293] This example illustrates a computer-generated model for the
recovery of the extracted diols from the extractant solvent mixture
by back extraction with water. The extract phase from Example 16,
is fed to the bottom stage of an extraction column comprising
twelve theoretical stages. The water back extractant is introduced
on stage twelve (from bottom). The water to feed weight ratio is
0.6:1.0. The system was modeled using the Kremser method, as
described in Treybal, Liquid Extraction, 2.sup.nd Ed., McGraw Hill
Book Company, 1963, pp. 248-252, with partition coefficients
correlated from the data of Example 3 and 6. Material balance (all
values in kg/hr) data are given in Table 16. Recovery of 1,2-BDO to
the water extract product is 99.93 weight percent.
TABLE-US-00029 TABLE 16 1,2- 1,2- Stream ID EG PDO BDO Water 2-EH
Total Extract Phase, 0.0163 0.0008 0.0314 1.00 235.09 236.14
Example 16 Extractant 141.69 0.00 141.69 TOTAL IN 0.0163 0.00 0.03
142.69 235.09 377.83 Extract 0.0163 0.00078 0.03137 140.39 0.05
140.49 Raffinate 0.00 0.00000 0.00002 2.29 235.04 237.33 TOTAL OUT
0.02 0.00 0.03 142.69 235.09 377.83
Example 19
[0294] This example illustrates a computer-generated model for the
recovery of the extracted diols from the extractant solvent mixture
by distillation. The extract phase from Example 17, is fed to the
eighth stage of a fifteen theoretical stage distillation column
operated at 150 torr, and a reflux ratio of 2:1. Heterogeneous
azeotropes of water, 1,2-PDO, 1,2-BDO, and EG with decane (the
hydrocarbon component of the extractant,) are distilled as overhead
product, allowed to decant into two phases, and the
hydrocarbon-rich phase is refluxed back to the column. The water
layer of the decanter comprising essentially all of the EG,
1,2-PDO, 1,2-BDO, and water is continuously removed from the
column/decanter. In this fashion, the decane/C923 bottoms product
is purified for recycle to the extraction step of Example 17.
Example 20
[0295] This example illustrates a computer-generated model for a
single feed distillation of an EG/1,2-BDO mixed diol feed
comprising 80 weight percent EG and 20 weight percent 1,2-BDO. One
hundred kg/hr of the aforementioned mixed diol feed is fed to
eighteenth stage of a distillation column comprising thirty-six
theoretical stages (numbered from the top down), a reboiler, and a
condenser. The column is operated at 0.2 bar absolute in the
distillate at a mass reflux ratio of 2.82:1. Heat duty in the
reboiler is calculated as 260.4 MJ/hr. Material balance (all values
in kg/hr) data are given in Table 17. Recovery of EG to the bottoms
product is only 25 weight percent, as the EG/1,2-BDO azeotrope
severely limits the practical separation of EG and 1,2-BDO. The
purified EG bottoms product consists of 2000 ppm by weight 1,2-BDO
and 99.8 weight percent EG.
TABLE-US-00030 TABLE 17 Bottoms Distillate Feed EG 19.958 60.042
80.0 1,2-BDO 0.04 19.960 20.0
Example 21
[0296] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
80 weight percent EG and 20 weight percent 1,2-BDO. The extractant
for the fractional extraction contains 99.1 weight percent
2-ethylhexanol and 0.9 weight percent water. The column comprises
fifteen theoretical stages. The mixed diol feed is fed on stage ten
(from the bottom), the extractant is introduced on stage one (from
bottom), and the water wash on stage 15. The water wash to mixed
diol feed weight ratio is 0.16:1.0, and the extractant to mixed
diol feed ratio is 4.3:1.0. The system was modeled using the
Kremser method, as described in Treybal, Liquid Extraction,
2.sup.nd Ed., McGraw Hill Book Company, 1963, pp. 248-252, with
partition coefficients correlated from the data of Examples 3 and
6. Material balance (all values in kg/hr) data are given in Table
18. Recovery of 1,2-BDO to the extract is 99.3 weight percent.
Recovery of EG to the raffinate is 99.81 weight percent. The
raffinate comprises 0.2 weight percent 1,2-BDO and 99.8 weight
percent EG on a solvent-free and water-free basis.
TABLE-US-00031 TABLE 18 Stream ID EG 1,2-BDO Water 2-EH Total Mixed
Diol 80.00 20.00 100.00 Feed Extractant 4.30 430.00 434.30 Water
Wash 16.10 16.10 TOTAL IN 80.00 20.00 20.40 430.00 550.40 Extract
0.15 19.87 1.65 420.93 442.60 Raffinate 79.85 0.15 18.75 9.07
107.80 TOTAL OUT 80.0 20.0 20.40 430.00 550.40
Example 22
[0297] This example illustrates a computer-generated material
balance for a fractional extraction of a mixed diol feed comprising
80 weight percent 1,2-PDO, 20 weight percent 1,2-BDO. The
extractant for the fractional extraction contains 87.5 weight
percent Cyanex.RTM. 923, 9.72 weight percent heptane, and 2.78
weight percent water. The column comprises fifteen theoretical
stages. The mixed diol feed is fed on stage ten (from the bottom),
the extractant is introduced on stage one (from bottom), and the
water wash on stage 15. The water wash to mixed diol feed weight
ratio is 0.795:1.0, and the extractant to mixed diol feed ratio is
1.8:1.0. The system was modeled using the Kremser method, as
described in Treybal, Liquid Extraction, 2.sup.nd Ed., McGraw Hill
Book Company, 1963, pp. 248-252, with partition coefficients
correlated from the data of Example 10. Material balance (all
values in kg/hr) data are given in Table 19. Recovery of 1,2-BDO to
the extract product is 99.87 weight percent. Recovery of 1,2-PDO to
the raffinate is 98.98 weight percent. The raffinate comprises 333
ppm by weight 1,2-BDO and 99.967 1,2-PDO on a solvent-free and
water-free basis.
TABLE-US-00032 TABLE 19 1,2- 1,2- Stream ID PDO BDO Water C923 HEPT
Total Mixed Diol 80.00 20.00 100.00 Feed Extractant 5.01 157.50
17.50 180.01 Water Wash 79.47 79.47 TOTAL IN 80.00 20.00 84.47
157.50 17.50 359.47 Extract 0.82 19.97 14.75 157.48 17.50 210.53
Raffinate 79.18 0.026 69.72 0.02 0.00 148.94
Example 23
[0298] This example illustrates the separation of diols from a
glycerol-containing aqueous mixture. A standard diol/glycerol
solution was prepared comprising an aqueous solution of 84 weight
percent water, 10 weight percent glycerol (GLY), 2 weight percent
each of ethylene glycol (EG), 1,2-propanediol (1,2-PDO), and
1,2-butanediol (1,2-BDO). Fifteen grams of this standard solution
was added to a separate glass vial along with fifteen grams of each
of the nonpolar solvents listed in Table 20. The contents were
mixed vigorously and allowed to settle and separate into two clear
phases. The phases were analyzed by gas chromatography to determine
glycerol, EG, 1,2-PDO, 1,2-BDO weight percentages. These analytical
results were used to calculate partition coefficients and
selectivities. All experiments were conducted at room temperature.
Results are summarized in Table 20.
TABLE-US-00033 TABLE 20 P(1,2- P(1,2- S(EG/ S(1,2- S(1,2- Ex
Solvent P(EG) PDO) BDO) P(GLY) GLY) PDO/GLY) BDO/GLY) 23-1
n-pentanol 0.19 0.40 1.11 0.07 2.54 5.44 15.05 23-2 2-EH 0.05 0.13
0.42 0.01 4.99 12.23 38.53 23-3 EA 0.04 0.10 0.29 0.01 5.31 11.57
34.70 23-4 MIBK 0.02 0.06 0.20 0.00 7.56 18.10 64.73 23-5 50 wt %
Heptane/ 0.07 0.19 0.74 0.02 3.01 7.68 29.85 50 wt % C923
Example 24
[0299] This example illustrates the separation of diols from a
glycerol-rich aqueous mixture. A standard diol/glycerol solution
was prepared comprising 84 weight percent glycerol (GLY), 10 weight
percent water, 2 weight percent each of ethylene glycol (EG),
1,2-propanediol (1,2-PDO), and 1,2-butanediol (1,2-BDO). Fifteen
grams of this standard solution was added to a separate glass vial
along with fifteen grams of each of the nonpolar solvents listed in
Table 21. The contents were mixed vigorously and allowed to settle
and separate into two clear phases. The phases were analyzed by gas
chromatography to determine glycerol, EG, 1,2-PDO, 1,2-BDO weight
percentages. These analytical results were used to calculate
partition coefficients and selectivities. All experiments were
conducted at room temperature. Results are summarized in Table
21.
TABLE-US-00034 TABLE 21 P(1,2- P(1,2- S(1,2- S(1,2- Ex Solvent
P(EG) PDO) BDO) P(GLY) S(EG/GLY) PDO/GLY) BDO/GLY) 24-1 n-pentanol
0.57 0.97 1.66 0.32 1.76 3.01 5.14 24-2 2-EH 0.17 0.40 0.89 0.05
3.46 7.85 17.58 24-3 EA 0.08 0.18 0.41 0.02 4.65 11.10 24.65 24-4
MIBK 0.06 0.14 0.33 0.01 5.51 13.27 32.06 24-5 50 wt % Heptane/
0.18 0.46 1.28 0.07 2.78 6.92 19.28 50 wt % C923
Example 25
[0300] This example illustrates the separation of diols from
glucose (GLU). A standard diol/glucose solution was prepared
comprising an aqueous solution of 10 weight percent glucose (GLU),
84 weight percent water, 2 weight percent each of ethylene glycol
(EG), 1,2-propanediol (1,2-PDO), and 1,2-butanediol (1,2-BDO).
Fifteen grams of this standard solution was added to a separate
glass vial along with fifteen grams of each of the nonpolar
solvents listed in Table 22. The contents were mixed vigorously and
allowed to settle and separate into two clear phases. The phases
were analyzed by gas chromatography to determine glycerol, EG,
1,2-PDO, 1,2-BDO weight percentages. These analytical results were
used to calculate partition coefficients and selectivities. All
experiments were conducted at room temperature. Results are
summarized in Table 22.
TABLE-US-00035 TABLE 22 P(1,2- P(1,2- S(1,2- S(1,2- Ex Solvent
P(EG) PDO) BDO) P(GLU) S(EG/GLU) PDO/GLU) BDO/GLU) 25-1 n-pentanol
0.20 0.43 1.21 0.01 15.02 32.38 91.20 25-2 2-EH 0.06 0.14 0.46 0.00
.infin. .infin. .infin. 25-3 EA 0.04 0.11 0.32 0.00 .infin. .infin.
.infin. 25-4 MIBK 0.03 0.06 0.21 0.00 .infin. .infin. .infin. 25-5
50 wt % Heptane/ 0.08 0.20 0.81 0.004 20.51 53.28 213.02 50 wt %
C923
* * * * *