U.S. patent application number 14/105230 was filed with the patent office on 2014-06-19 for fragrance materials.
This patent application is currently assigned to The Procter & Gamble Company. The applicant listed for this patent is The Procter & Gamble Company. Invention is credited to Jonathan Robert CETTI, Zerlina Guzdar DUBOIS, Virginia Tzung-Hwei HUTCHINS, Michael Wayne KINSEY, Christine Marie READNOUR.
Application Number | 20140170194 14/105230 |
Document ID | / |
Family ID | 49881147 |
Filed Date | 2014-06-19 |
United States Patent
Application |
20140170194 |
Kind Code |
A1 |
CETTI; Jonathan Robert ; et
al. |
June 19, 2014 |
FRAGRANCE MATERIALS
Abstract
The present application relates to perfume raw materials,
perfumes, perfume delivery systems and consumer products comprising
such perfume raw materials, perfumes and/or such perfume delivery
systems, as well as processes for making and using such perfume raw
materials, perfume delivery systems and consumer products. The
perfumes disclosed herein expand the perfume communities'
options.
Inventors: |
CETTI; Jonathan Robert;
(Mason, OH) ; DUBOIS; Zerlina Guzdar; (Mason,
OH) ; HUTCHINS; Virginia Tzung-Hwei; (Cincinnati,
OH) ; KINSEY; Michael Wayne; (Lebanon, OH) ;
READNOUR; Christine Marie; (Fort Mitchell, KY) |
|
Applicant: |
Name |
City |
State |
Country |
Type |
The Procter & Gamble Company |
Cincinnati |
OH |
US |
|
|
Assignee: |
The Procter & Gamble
Company
Cincinnati
OH
|
Family ID: |
49881147 |
Appl. No.: |
14/105230 |
Filed: |
December 13, 2013 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
|
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61737257 |
Dec 14, 2012 |
|
|
|
61869241 |
Aug 23, 2013 |
|
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61879217 |
Sep 18, 2013 |
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Current U.S.
Class: |
424/401 ;
132/200; 134/25.2; 134/26; 134/42; 424/65; 424/76.8; 510/103;
512/4; 512/7; 8/137 |
Current CPC
Class: |
A61K 8/40 20130101; A61Q
15/00 20130101; C11B 9/0023 20130101; A61K 8/11 20130101; A61K 8/28
20130101; C11B 9/0084 20130101; A61K 8/738 20130101; C11D 3/502
20130101; A61Q 5/02 20130101; A61Q 19/00 20130101; C11B 9/0011
20130101; A61K 2800/56 20130101; A61Q 13/00 20130101; C11D 3/001
20130101; A61K 8/445 20130101; A61K 8/49 20130101; C11D 11/0017
20130101; A61K 8/4986 20130101; A61K 8/602 20130101; A61K 2800/77
20130101; C11B 9/0096 20130101; A61K 8/4926 20130101; A61K 8/41
20130101; A61Q 19/10 20130101; A61K 8/496 20130101; A61K 8/494
20130101; A61L 9/01 20130101; C11B 9/0092 20130101; A61K 8/46
20130101 |
Class at
Publication: |
424/401 ; 512/7;
510/103; 512/4; 8/137; 424/76.8; 424/65; 132/200; 134/42; 134/26;
134/25.2 |
International
Class: |
A61K 8/11 20060101
A61K008/11; C11D 3/50 20060101 C11D003/50; A61Q 13/00 20060101
A61Q013/00; A61Q 19/00 20060101 A61Q019/00; A61Q 15/00 20060101
A61Q015/00; A61Q 19/10 20060101 A61Q019/10; A61Q 5/02 20060101
A61Q005/02; C11B 9/00 20060101 C11B009/00; A61L 9/01 20060101
A61L009/01 |
Claims
1. A perfume comprising, based on total perfume weight, a perfume
raw material selected from the group consisting of: a) from about
0.0000001% to about 10% of a perfume raw material comprising a
thiol moiety; b) from about 0.0000001% to about 10% of a perfume
raw material comprising a sulfide moiety; c) from about 0.000001%
to about 10% of a perfume raw material comprising a thiazole
moiety; d) from about 0.00000005% to about 5% of a perfume raw
material comprising a pyrazine moiety; e) from about 0.00001% to
about 20% of a perfume raw material comprising a nitrile moiety; f)
from about 0.000001% to about 10% of a perfume raw material
comprising an indole moiety; g) from about 0.0000001% to about 10%
of a perfume raw material comprising an oxathiane moiety; h) from
about 0.00001% to about 10% of a perfume raw material comprising an
oxime moiety; i) from about 0.00001% to about 20% of a perfume raw
material comprising an amine moiety; j) from about 0.00000005% to
about 5% of a perfume raw material comprising an isothiocyanate; k)
from about 0.00000005% to about 5% of a perfume raw material
comprising a diamine moiety; l) from about 0.000001% to about 10%
of a perfume raw material comprising oxygen, sulfur, and nitrogen;
and m) mixtures thereof, with the proviso that the sum of the
percentage of said perfume raw materials cannot exceed 100%.
2. A perfume according to claim 1 comprising, based on total
perfume weight, a perfume raw material selected from the group
consisting of claim 1 items: a), b) c), d), g), h), j), k), l), m)
and mixtures thereof.
3. A perfume according to claim 2 comprising, based on total
perfume weight, a perfume raw material selected from the group
consisting of claim 1 items: a), b) c), d), g), m) and mixtures
thereof.
4. A perfume according to claim 1 wherein: a) said perfume raw
material comprising a thiol moiety is selected from the group
consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; methanethiol; Ethanethiol;
prop-2-ene-1-thiol; propane-2-thiol; 2-methylpropane-2-thiol;
propane-1-thiol; butane-2-thiol; butane-1-thiol;
2-methylpropane-1-thiol; methyldisulfanylmethane;
2-methylbutane-2-thiol; 3-methylbutane-2-thiol;
3-methylbutane-2-thiol; pentane-2-thiol; pentane-1-thiol;
2-methylbutane-1-thiol; cyclopentanethiol;
3-methyldisulfanylprop-1-ene; methylsulfanyldisulfanylmethane;
1-methyldisulfanylpropane; ethane-1,2-dithiol;
1-(methyldisulfanyl)prop-1-ene; 3-sulfanylbutan-2-one;
ethyldisulfanylethane; hexane-1-thiol; 1-ethyldisulfanylpropane;
thiophene-2-thiol; propane-1,3-dithiol; 3-sulfanylpentan-2-one;
2-propan-2-yldisulfanylpropane; butane-1,4-dithiol; benzenethiol;
ethylsulfanyldisulfanylethane;
3-methylsulfanyldisulfanylprop-1-ene;
1-methylsulfanyldisulfanylpropane; butane-2,3-dithiol;
4-methyl-4-sulfanylpentan-2-one; 3-prop-2-enyldisulfanylprop-1-ene;
1-methoxyhexane-3-thiol; ethyl 2-sulfanylpropanoate;
1-(prop-2-enyldisulfanyl)propane; 1-propyldisulfanylpropane;
1-(4-hydroxy-3-methoxyphenyl)ethanone butane-1,3-dithiol;
1-propyldisulfanylprop-1-ene; 2-methylbenzenethiol;
thiophen-2-ylmethanethiol; 3-sulfanylbutan-2-ol; phenylmethanethiol
pentane-1,5-dithiol; 2-ethylbenzenethiol;
3-prop-2-enylsulfanyldisulfanylprop-1-ene;
methyldisulfanyldisulfanylmethane;
1-propylsulfanyldisulfanylpropane;
2,7,7-trimethylbicyclo[3.1.1]heptane-2-thiol;
2,6-dimethylbenzenethiol; 2-phenylethanethiol; hexane-1,6-dithiol;
2-(methyldisulfanylmethyl)furan; pyridin-2-ylmethanethiol;
2-methoxybenzenethiol;
(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)methanethiol;
methyldisulfanylbenzene; 1-butyldisulfanylbutane;
(4-methoxyphenyl)methanethiol; 2-sulfanylpropanoic acid; ethyl
2-methyldisulfanylpropanoate;
(2E)-3,7-dimethylocta-2,6-diene-1-thiol;
3,7-dimethylocta-2,6-diene-1-thiol; pyrazin-2-ylmethanethiol;
methyldisulfanylmethylbenzene;
2-methyl-5-(1-sulfanylpropan-2-yl)cyclohexane-1-thiol;
octane-1,8-dithiol; 2-pyrazin-2-ylethanethiol; naphthalene-2-thiol;
2-oxo-3-sulfanylpropanoic acid; 2-thiophen-2-yldisulfanylthiophene;
cyclohexyldisulfanylcyclohexane;
2-(furan-2-ylmethyldisulfanylmethyl)furan; phenyldisulfanylbenzene;
benzyldisulfanylmethylbenzene; 8-Hydroxy-5-quinolinesulfonic acid;
bis(3-methylbutyl) 2-sulfanylbutanedioate; 2-aminoethanesulfonic
acid; 2-phenyl-3H-benzimidazole-5-sulfonic acid;
2-methyl-2-sulfanylpentan-1-ol; and mixtures thereof; b) said
perfume raw material comprising a sulfide moiety is selected from
the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan;
methylsulfanylmethane; methylsulfanylethane;
3-methylsulfanylprop-1-ene; S-methyl ethanethioate;
ethylsulfanylethane; 1-methylsulfanylpropane; S-ethyl
ethanethioate; 1-methylsulfanylbutane;
2-propan-2-ylsulfanylpropane; bis(methylsulfanyl)methane;
1-ethylsulfanylpropane; thiolane; 1-propylsulfanylpropane;
1-ethylsulfanylbutane; S-ethyl propanethioate; S-methyl
butanethioate; S-methyl 3-methylbutanethioate;
3-methylsulfanylpropanal; 3-prop-2-enylsulfanylprop-1-ene; methyl
2-methylsulfanylacetate; S-prop-2-enyl propanethioate;
1-methylsulfanylbutan-2-one; 4-methylsulfanylbutan-2-one;
3-methylsulfanylpropan-1-am; 2,4,6-trimethyl-1,3,5-trithiane;
3-methylsulfanylbutanal; 2-methyl-1,3-thiazolidine;
2-methyl-4,5-dihydro-1,3-thiazole; ethyl 2-methylsulfanylacetate;
methyl 3-methylsulfanylpropanoate; S-propan-2-yl
3-methylbutanethioate; 4-methyl-4-methylsulfanylpentan-2-one;
2-methyl-1,3-dithiolane; methyl 2-methylsulfanylbutanoate; S-methyl
furan-2-carbothioate; S-propan-2-yl 3-methylbut-2-enethioate;
thiolan-3-one; 3,5-diethyl-1,2,4-trithiolane;
methylsulfanylmethylbenzene; 3-methylsulfanylpropan-1-ol;
2-(propan-2-ylsulfanylmethyl)furan; 2-methyl-5-methylsulfanylfuran;
S-(furan-2-ylmethyl) methanethioate; 1,2,4-trithiolane;
2-methylthiolan-3-one; 4-methylsulfanylbutan-1-ol; S-butan-2-yl
3-methylbutanethioate; S-butan-2-yl 3-methylbut-2-enethioate;
S-(furan-2-ylmethyl)ethanethioate; 2-propyl-1,3-thiazolidine;
3-methyl-1,1-bis(methylsulfanyl)butane; 3-ethylsulfanylpropan-1-ol;
S-methyl benzenecarbothioate; 3,5-dimethyl-1,2,4-trithiolane;
S-butan-2-yl 2-methylbutanethioate; methylsulfanylbenzene;
1-pentylsulfanylpentane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-methyl-4-propyl-1,3-oxathiane; ethyl
2-methyl-2-methylsulfanylpropanoate; S-(furan-2-ylmethyl)
propanethioate; 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
3-methyl-1,2,4-trithiane; methylsulfanylmethyl hexanoate;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone; 3-methylsulfanylpropanoic
acid; 5-methylsulfanyl-2-(methylsulfanylmethyl)pent-2-enal;
4,5-dimethyl-2-(2-methylpropyl)-2,5-dihydro-1,3-thiazole;
3-methylsulfanylhexan-1-ol; 2-methyl-4,5-dihydrofuran-3-thiol
acetate; 4-(3-oxobutylsulfanyl)butan-2-one;
3-methylsulfanylbutanoic acid; 2-methylsulfanylpyrazine;
2-methyl-3-methylsulfanylpyrazine;
2-(furan-2-ylmethylsulfanylmethyl)furan;
2-(methylsulfanylmethyl)pyrazine;
3,5-di(propan-2-yl)-1,2,4-trithiolane; 2-methylsulfanylphenol;
2-methyl-3-methylsulfanylpyrazine; ethyl
3-(furan-2-ylmethylsulfanyl)propanoate;
2,2,4,4,6,6-hexamethyl-1,3,5-trithiane;
2-methyl-5,7-dihydrothieno[3,4-d]pyrimidine;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolan-
e]; 2,5-dimethyl-1,4-dithiane-2,5-diol; Methyl 2-thiofuroate and
mixtures thereof; c) said perfume raw material comprising a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
2,4,5-Trimethylthiazole; 2-isopropyl-4-methylthiazole;
4-vinyl-5-methylthiazole; 2,4-Dimethyl-5-acetylthiazole
1,3-thiazole; 4-methyl-1,3-thiazole; 2,4-dimethyl-1,3-thiazole;
4,5-dimethyl-1,3-thiazole; 2,5-dimethyl-1,3-thiazole;
5-ethenyl-4-methyl-1,3-thiazole; 2-ethyl-4-methyl-1,3-thiazole;
4-ethyl-2-methyl-1,3-thiazole; 2-propyl-1,3-thiazole;
2,4,5-trimethyl-1,3-thiazole; 2-ethyl-1,3-thiazole;
2-ethoxy-1,3-thiazole; 2-butan-2-yl-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole; 2-ethyl-4,5-dimethyl-1,3-thiazole;
1,3-benzothiazole; 2,5-diethyl-4-methyl-1,3-thiazole;
1-(1,3-thiazol-2-yl)propan-1-one;
4,5-dimethyl-2-(2-methylpropyl)-1,3-thiazole;
2-methyl-1,3-benzothiazole;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
4-methyl-2-propan-2-yl-1,3-thiazole; and mixtures thereof; d) said
perfume raw material comprising a pyrazine moiety is selected from
the group consisting of 2-methoxy-3-(2-methylpropyl)pyrazine;
2,3-dimethylpyrazine; 1-pyrazin-2-ylethanone;
2-methyl-3-methylsulfanylpyrazine; Pyrazine; 2-methylpyrazine;
2-ethenylpyrazine; 2-ethylpyrazine; 2,6-dimethylpyrazine;
2,5-dimethylpyrazine; 2-prop-1-en-2-ylpyrazine;
2-propan-2-ylpyrazine; 2-methoxypyrazine;
2-ethenyl-5-methylpyrazine; 2-ethyl-5-methylpyrazine;
2-Ethyl-6-methylpyrazine; 2-Ethyl-3-Methyl-Pyrazine;
2-propylpyrazine; 2,3,5-trimethylpyrazine; 2-tert-butylpyrazine;
pyrazin-2-amine; 2-(2-methylpropyl)pyrazine;
2-methyl-5-propan-2-ylpyrazine; 2-(methoxymethyl)pyrazine;
2,3-diethylpyrazine; 2-ethyl-3,(5 OR 6)-dimethylpyrazine;
2-ethyl-3,5-dimethylpyrazine; 3-ethyl-2,5-dimethylpyrazine;
3-ethyl-2,5-dimethylpyrazine; 2-ethyl-3,5-dimethylpyrazine;
2-methyl-3-propylpyrazine; 2,3,5,6-tetramethylpyrazine;
7-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine;
2-methylsulfanylpyrazine; 2-methyl-3-methylsulfanylpyrazine;
2-ethoxy-3-ethylpyrazine; 2-Isobutyl-3-methylpyrazine;
pyrazin-2-ylmethanethiol; 3,5-dimethyl-2-propylpyrazine;
2-ethyl-3-methoxypyrazine; 2-ethoxy-3-methylpyrazine;
2-ethyl-5-methoxypyrazine; 5,6,7,8-tetrahydroquinoxaline;
2-ethoxy-3-propan-2-ylpyrazine; 2-(methylsulfanylmethyl)pyrazine;
3,5-dimethyl-2-(2-methylpropyl)pyrazine;
2,3-diethyl-5-methylpyrazine; 3,5-Diethyl-2-methylpyrazine;
2,5-dimethyl-3-(2-methylpropyl)pyrazine;
2-methyl-6-propoxypyrazine; 2-(2-methylpropoxy)pyrazine;
1-(3-methylpyrazin-2-yl)ethanone;
2-methyl-3-methylsulfanylpyrazine; 2-methoxy-3-propan-2-ylpyrazine;
quinoxaline; 3-butyl-2,5-dimethylpyrazine;
2-butyl-3,5-dimethylpyrazine; 2-pyrazin-2-ylethanethiol;
1-(3-ethylpyrazin-2-yl)ethanone;
1-(3,5-dimethylpyrazin-2-yl)ethanone;
2-butan-2-yl-3-methoxypyrazine; 2-methylquinoxaline;
5-Methylquinoxaline; 2-methoxy-3-(4-methylpentyl)pyrazine;
2,3-dimethylquinoxaline; 2-(cyclohexylmethyl)pyrazine;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine and mixtures
thereof; e) said perfume raw material comprising a nitrile moiety
is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
f) said perfume raw material comprising a indole moiety is selected
from the group consisting of 1H-indole, 3-methyl-1H-indole; and
mixtures thereof; g) said perfume raw material comprising a
oxathiane moiety is selected from the group consisting of
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane,
2-methyl-4-propyl-1,3-oxathiane, 2-pentyl-4-propyl-1,3-oxathiane;
and mixtures thereof; h) said perfume raw material comprising a
oxime moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
N-(5-methylheptan-3-ylidene)hydroxylamine, and mixtures thereof; i)
said perfume raw material comprising a amine moiety is selected
from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine; 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof;
5. A perfume according to claim 1 wherein said perfume raw material
comprises at least one sulfur, oxygen and nitrogen atom, said
perfume raw material being selected from the group consisting of
2-(4-methyl-1,3-thiazol-5-yl)ethanol; 1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine;
2,4-Dimethyl-5-acetylthiazole; 2-ethoxy-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone;
1-(1,3-thiazol-2-yl)propan-1-one;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
8-Hydroxy-5-quinolinesulfonic acid; 2-aminoethanesulfonic acid;
2-phenyl-3H-benzimidazole-5-sulfonic acid; and mixtures
thereof.
6. A perfume according to claim 1 wherein: a. said perfume raw
material comprising a thiol moiety is selected from the group
consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; and mixtures thereof; b. said
perfume raw material comprising a sulfide moiety is selected from
the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan; and
mixtures thereof; c. said perfume raw material comprising a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
and mixtures thereof; d. said perfume raw material comprising a
pyrazine moiety is selected from the group consisting of
2-methoxy-3-(2-methylpropyl)pyrazine; 2,3-dimethylpyrazine;
1-pyrazin-2-ylethanone; 2-methyl-3-methylsulfanylpyrazine; and
mixtures thereof; e. said perfume raw material comprising a nitrile
moiety is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
f. said perfume raw material comprising a indole moiety is selected
from the group consisting of 1H-indole; g. said perfume raw
material comprising a oxathiane moiety is selected from the group
consisting of (2R,4S)-2-methyl-4-propyl-1,3-oxathiane; h. said
perfume raw material comprising a oxime moiety is selected from the
group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
i. said perfume raw material comprising a amine moiety is selected
from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine, 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof; j. said perfume raw material comprising
oxygen, sulfur, and nitrogen is selected from the group consisting
of 2-(4-methyl-1,3-thiazol-5-yl)ethanol,
1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane; and mixtures
thereof.
7. A perfume according to claim 1 comprising a perfume raw material
selected from the group consisting of: a. 1-butylsulfanylbutane;
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane; and
4-methoxy-2-methylbutane-2-thiol; b.
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and 7-hydroxy-3,7-dimethyloctanal;
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; c.
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
7-Oxa-1-thia-4-azaspiro[4.4]nonane; and 6-methyl-,
1-(1,3-thiazol-2-yl)ethanone; d.
2-methoxy-3-(2-methylpropyl)pyrazine; 1-pyrazin-2-ylethanone; and
2,3-dimethylpyrazine; e. 2-(methylsulfanylmethyl)furan; ethyl
3-methylsulfanylpropanoate; and 1-butylsulfanylbutane; f.
5-methyl-5-sulfanylhexan-3-one;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one; and
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; g.
2-methoxy-3-(2-methylpropyl)pyrazine; 3,7-dimethyloct-6-enenitrile;
and methyl 2-aminobenzoate; h. 2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol; and
4-methyl-2-propan-2-yl-1,3-thiazole; i.
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; and
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and j. mixtures thereof.
8. A perfume having: a) a two week anti-habituation index of at
least 0, 1, 2, 3, or 4; b) a four week anti-habituation index of at
least 0, 1, 2, 3 or 4; c) a two week anti-habituation index of 0,
1, 2, 3 or 4; and/or d) a four week anti-habituation index of 0, 1,
2, 3 or 4.
9. A perfume raw material having a two week anti-habituation index
of at least 0, preferably at least 1; a four week anti-habituation
index of at least 0; a two week anti-habituation index of at least
0, 1, 2, 3, or 4; and/or a four week anti-habituation index of 0,
1, 2, 3, or 4, with the proviso that said perfume raw material is
not: a) a perfume raw material comprising a thiol moiety is
selected from the group consisting of
5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; methanethiol; Ethanethiol;
prop-2-ene-1-thiol; propane-2-thiol; 2-methylpropane-2-thiol;
propane-1-thiol; butane-2-thiol; butane-1-thiol;
2-methylpropane-1-thiol; methyldisulfanylmethane;
2-methylbutane-2-thiol; 3-methylbutane-2-thiol;
3-methylbutane-2-thiol; pentane-2-thiol; pentane-1-thiol;
2-methylbutane-1-thiol; cyclopentanethiol;
3-methyldisulfanylprop-1-ene; methylsulfanyldisulfanylmethane;
1-methyldisulfanylpropane; ethane-1,2-dithiol;
1-(methyldisulfanyl)prop-1-ene; 3-sulfanylbutan-2-one;
ethyldisulfanylethane; hexane-1-thiol; 1-ethyldisulfanylpropane;
thiophene-2-thiol; propane-1,3-dithiol; 3-sulfanylpentan-2-one;
2-propan-2-yldisulfanylpropane; butane-1,4-dithiol; benzenethiol;
ethylsulfanyldisulfanylethane;
3-methylsulfanyldisulfanylprop-1-ene;
1-methylsulfanyldisulfanylpropane; butane-2,3-dithiol;
4-methyl-4-sulfanylpentan-2-one; 3-prop-2-enyldisulfanylprop-1-ene;
1-methoxyhexane-3-thiol; ethyl 2-sulfanylpropanoate;
1-(prop-2-enyldisulfanyl)propane; 1-propyldisulfanylpropane;
1-(4-hydroxy-3-methoxyphenyl)ethanone butane-1,3-dithiol;
1-propyldisulfanylprop-1-ene; 2-methylbenzenethiol;
thiophen-2-ylmethanethiol; 3-sulfanylbutan-2-ol; phenylmethanethiol
pentane-1,5-dithiol; 2-ethylbenzenethiol;
3-prop-2-enylsulfanyldisulfanylprop-1-ene;
methyldisulfanyldisulfanylmethane;
1-propylsulfanyldisulfanylpropane;
2,7,7-trimethylbicyclo[3.1.1]heptane-2-thiol;
2,6-dimethylbenzenethiol; 2-phenylethanethiol; hexane-1,6-dithiol;
2-(methyldisulfanylmethyl)furan; pyridin-2-ylmethanethiol;
2-methoxybenzenethiol;
(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)methanethiol;
methyldisulfanylbenzene; 1-butyldisulfanylbutane;
(4-methoxyphenyl)methanethiol; 2-sulfanylpropanoic acid; ethyl
2-methyldisulfanylpropanoate;
(2E)-3,7-dimethylocta-2,6-diene-1-thiol;
3,7-dimethylocta-2,6-diene-1-thiol; pyrazin-2-ylmethanethiol;
methyldisulfanylmethylbenzene;
2-methyl-5-(1-sulfanylpropan-2-yl)cyclohexane-1-thiol;
octane-1,8-dithiol; 2-pyrazin-2-ylethanethiol; naphthalene-2-thiol;
2-oxo-3-sulfanylpropanoic acid; 2-thiophen-2-yldisulfanylthiophene;
cyclohexyldisulfanylcyclohexane;
2-(furan-2-ylmethyldisulfanylmethyl)furan; phenyldisulfanylbenzene;
benzyldisulfanylmethylbenzene; 8-Hydroxy-5-quinolinesulfonic acid;
bis(3-methylbutyl) 2-sulfanylbutanedioate; 2-aminoethanesulfonic
acid; 2-phenyl-3H-benzimidazole-5-sulfonic acid;
2-methyl-2-sulfanylpentan-1-ol; and mixtures thereof; b) a perfume
raw material comprising a sulfide moiety is selected from the group
consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan;
methylsulfanylmethane; methylsulfanylethane;
3-methylsulfanylprop-1-ene; S-methyl ethanethioate;
ethylsulfanylethane; 1-methylsulfanylpropane; S-ethyl
ethanethioate; 1-methylsulfanylbutane;
2-propan-2-ylsulfanylpropane; bis(methylsulfanyl)methane;
1-ethylsulfanylpropane; thiolane; 1-propylsulfanylpropane;
1-ethylsulfanylbutane; S-ethyl propanethioate; S-methyl
butanethioate; S-methyl 3-methylbutanethioate;
3-methylsulfanylpropanal; 3-prop-2-enylsulfanylprop-1-ene; methyl
2-methylsulfanylacetate; S-prop-2-enyl propanethioate;
1-methylsulfanylbutan-2-one; 4-methylsulfanylbutan-2-one;
3-methylsulfanylpropan-1-am; 2,4,6-trimethyl-1,3,5-trithiane;
3-methylsulfanylbutanal; 2-methyl-1,3-thiazolidine;
2-methyl-4,5-dihydro-1,3-thiazole; ethyl 2-methylsulfanylacetate;
methyl 3-methylsulfanylpropanoate; S-propan-2-yl
3-methylbutanethioate; 4-methyl-4-methylsulfanylpentan-2-one;
2-methyl-1,3-dithiolane; methyl 2-methylsulfanylbutanoate; S-methyl
furan-2-carbothioate; S-propan-2-yl 3-methylbut-2-enethioate;
thiolan-3-one; 3,5-diethyl-1,2,4-trithiolane;
methylsulfanylmethylbenzene; 3-methylsulfanylpropan-1-ol;
2-(propan-2-ylsulfanylmethyl)furan; 2-methyl-5-methylsulfanylfuran;
S-(furan-2-ylmethyl) methanethioate; 1,2,4-trithiolane;
2-methylthiolan-3-one; 4-methylsulfanylbutan-1-ol; S-butan-2-yl
3-methylbutanethioate; S-butan-2-yl 3-methylbut-2-enethioate;
S-(furan-2-ylmethyl)ethanethioate; 2-propyl-1,3-thiazolidine;
3-methyl-1,1-bis(methylsulfanyl)butane; 3-ethylsulfanylpropan-1-ol;
S-methyl benzenecarbothioate; 3,5-dimethyl-1,2,4-trithiolane;
S-butan-2-yl 2-methylbutanethioate; methylsulfanylbenzene;
1-pentylsulfanylpentane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-methyl-4-propyl-1,3-oxathiane; ethyl
2-methyl-2-methylsulfanylpropanoate; S-(furan-2-ylmethyl)
propanethioate; 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
3-methyl-1,2,4-trithiane; methylsulfanylmethyl hexanoate;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone; 3-methylsulfanylpropanoic
acid; 5-methylsulfanyl-2-(methylsulfanylmethyl)pent-2-enal;
4,5-dimethyl-2-(2-methylpropyl)-2,5-dihydro-1,3-thiazole;
3-methylsulfanylhexan-1-ol; 2-methyl-4,5-dihydrofuran-3-thiol
acetate; 4-(3-oxobutylsulfanyl)butan-2-one;
3-methylsulfanylbutanoic acid; 2-methylsulfanylpyrazine;
2-methyl-3-methylsulfanylpyrazine;
2-(furan-2-ylmethylsulfanylmethyl)furan;
2-(methylsulfanylmethyl)pyrazine;
3,5-di(propan-2-yl)-1,2,4-trithiolane; 2-methylsulfanylphenol;
2-methyl-3-methylsulfanylpyrazine; ethyl
3-(furan-2-ylmethylsulfanyl)propanoate;
2,2,4,4,6,6-hexamethyl-1,3,5-trithiane;
2-methyl-5,7-dihydrothieno[3,4-d]pyrimidine;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolan-
e]; 2,5-dimethyl-1,4-dithiane-2,5-diol; Methyl 2-thiofuroate and
mixtures thereof; c) a perfume raw material comprising a thiazole
moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
2,4,5-Trimethylthiazole; 2-isopropyl-4-methylthiazole;
4-vinyl-5-methylthiazole; 2,4-Dimethyl-5-acetylthiazole
1,3-thiazole; 4-methyl-1,3-thiazole; 2,4-dimethyl-1,3-thiazole;
4,5-dimethyl-1,3-thiazole; 2,5-dimethyl-1,3-thiazole;
5-ethenyl-4-methyl-1,3-thiazole; 2-ethyl-4-methyl-1,3-thiazole;
4-ethyl-2-methyl-1,3-thiazole; 2-propyl-1,3-thiazole;
2,4,5-trimethyl-1,3-thiazole; 2-ethyl-1,3-thiazole;
2-ethoxy-1,3-thiazole; 2-butan-2-yl-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole; 2-ethyl-4,5-dimethyl-1,3-thiazole;
1,3-benzothiazole; 2,5-diethyl-4-methyl-1,3-thiazole;
1-(1,3-thiazol-2-yl)propan-1-one;
4,5-dimethyl-2-(2-methylpropyl)-1,3-thiazole;
2-methyl-1,3-benzothiazole;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
4-methyl-2-propan-2-yl-1,3-thiazole; and mixtures thereof; d) a
perfume raw material comprising a pyrazine moiety is selected from
the group consisting of 2-methoxy-3-(2-methylpropyl)pyrazine;
2,3-dimethylpyrazine; 1-pyrazin-2-ylethanone;
2-methyl-3-methylsulfanylpyrazine; Pyrazine; 2-methylpyrazine;
2-ethenylpyrazine; 2-ethylpyrazine; 2,6-dimethylpyrazine;
2,5-dimethylpyrazine; 2-prop-1-en-2-ylpyrazine;
2-propan-2-ylpyrazine; 2-methoxypyrazine;
2-ethenyl-5-methylpyrazine; 2-ethyl-5-methylpyrazine;
2-Ethyl-6-methylpyrazine; 2-Ethyl-3-Methyl-Pyrazine;
2-propylpyrazine; 2,3,5-trimethylpyrazine; 2-tert-butylpyrazine;
pyrazin-2-amine; 2-(2-methylpropyl)pyrazine;
2-methyl-5-propan-2-ylpyrazine; 2-(methoxymethyl)pyrazine;
2,3-diethylpyrazine; 2-ethyl-3,(5 OR 6)-dimethylpyrazine;
2-ethyl-3,5-dimethylpyrazine; 3-ethyl-2,5-dimethylpyrazine;
3-ethyl-2,5-dimethylpyrazine; 2-ethyl-3,5-dimethylpyrazine;
2-methyl-3-propylpyrazine; 2,3,5,6-tetramethylpyrazine;
7-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine;
2-methylsulfanylpyrazine; 2-methyl-3-methylsulfanylpyrazine;
2-ethoxy-3-ethylpyrazine; 2-Isobutyl-3-methylpyrazine;
pyrazin-2-ylmethanethiol; 3,5-dimethyl-2-propylpyrazine;
2-ethyl-3-methoxypyrazine; 2-ethoxy-3-methylpyrazine;
2-ethyl-5-methoxypyrazine; 5,6,7,8-tetrahydroquinoxaline;
2-ethoxy-3-propan-2-ylpyrazine; 2-(methylsulfanylmethyl)pyrazine;
3,5-dimethyl-2-(2-methylpropyl)pyrazine;
2,3-diethyl-5-methylpyrazine; 3,5-Diethyl-2-methylpyrazine;
2,5-dimethyl-3-(2-methylpropyl)pyrazine;
2-methyl-6-propoxypyrazine; 2-(2-methylpropoxy)pyrazine;
1-(3-methylpyrazin-2-yl)ethanone;
2-methyl-3-methylsulfanylpyrazine; 2-methoxy-3-propan-2-ylpyrazine;
quinoxaline; 3-butyl-2,5-dimethylpyrazine;
2-butyl-3,5-dimethylpyrazine; 2-pyrazin-2-ylethanethiol;
1-(3-ethylpyrazin-2-yl)ethanone;
1-(3,5-dimethylpyrazin-2-yl)ethanone;
2-butan-2-yl-3-methoxypyrazine; 2-methylquinoxaline;
5-Methylquinoxaline; 2-methoxy-3-(4-methylpentyl)pyrazine;
2,3-dimethylquinoxaline; 2-(cyclohexylmethyl)pyrazine;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine and mixtures
thereof; e) a perfume raw material comprising a nitrile moiety is
selected from the group consisting of 3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
f) a perfume raw material comprising a indole moiety is selected
from the group consisting of 1H-indole, 3-methyl-1H-indole; and
mixtures thereof; g) a perfume raw material comprising a oxathiane
moiety is selected from the group consisting of
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane,
2-methyl-4-propyl-1,3-oxathiane, 2-pentyl-4-propyl-1,3-oxathiane;
and mixtures thereof; h) a perfume raw material comprising a oxime
moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
N-(5-methylheptan-3-ylidene)hydroxylamine, and mixtures thereof; i)
a perfume raw material comprising a amine moiety is selected from
the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine; 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof.
10. A composition comprising a consumer product material and, based
on total composition weight, a perfume raw material selected from
the group consisting of: a) from about 0.00000001% to about 1% of a
perfume raw material comprising a thiol moiety; b) from about
0.00000001% to about 1% of a perfume raw material comprising a
sulfide moiety; c) from about 0.0000001% to about 1% of a perfume
raw material comprising a thiazole moiety; d) from about
0.000000005% to about 0.5% of a perfume raw material comprising a
pyrazine moiety; e) from about 0.000001% to about 2% of a perfume
raw material comprising a nitrile moiety; f) from about 0.0000001%
to about 1% of a perfume raw material comprising an indole moiety;
g) from about 0.00000001% to about 1% of a perfume raw material
comprising an oxathiane moiety; h) from about 0.000001% to about 1%
of a perfume raw material comprising an oxime moiety; i) from about
0.000001% to about 2% of a perfume raw material comprising an amine
moiety; j) from about 0.000000005% to about 0.5% of a perfume raw
material comprising an isothiocyanate; k) from about 0.000000005%
to about 0.5% of a perfume raw material comprising a diamine
moiety; l) from about 0.0000001% to about 1% of a perfume raw
material comprising oxygen, sulfur, and nitrogen; and m) mixtures
thereof. with the proviso that the sum of the percentage of said
perfume raw materials cannot exceed 100%.
11. The composition of claim 10 wherein said consumer product
material is selected from the group consisting of an antiperspirant
active, antimicrobial deodorant active, monohydric alcohol,
polyhydric alcohol, petrolatum, an emulsifier, a foaming
surfactant, a hair conditioner, gylcerine and mixtures thereof.
12. A composition comprising a consumer product material and a
perfume having: a) a two week anti-habituation index of at least 0;
b) a four week anti-habituation index of at least 0; c) a two week
anti-habituation index of 0, 1, 2, 3, or 4; and/or d) a four week
anti-habituation index of 0, 1, 2, 3, or 4.
13. A composition comprising a consumer product material and one or
more perfume raw materials, said composition having: a) a two week
anti-habituation index of at least 0; b) a four week
anti-habituation index of at least 0; c) a two week
anti-habituation index of 0, 1, 2, 3, or 4; and/or d) a four week
anti-habituation index of 0, 1, 2, 3, or 4.
14. A consumer product comprising, based on total consumer product
weight, from about 0.0001% to about 100% of a neat perfume
according to any of claims 1-8, 28-30 and/or a perfume raw material
according to claim 9, the balance of said consumer product
comprising an adjunct ingredient and/or a perfume delivery system
comprising a perfume according to any of claims 1-8, 28-30, and/or
a perfume raw material according to claim 9.
15. A deodorant comprising a perfume according to any of claims
1-8, 28-30, an encapsulate according to claim 25, a cyclic
oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9 and, based on total deodorant weight,
from about 0.01% to about 75% of an antimicrobial.
16. A deodorant according to claim 15, said deodorant comprising,
based on total deodorant weight, from about 10% to about 75%
glycol.
17. An antiperspirant comprising a perfume according to any of
claims 1-8, 28-30, an encapsulate according to claim 25, a cyclic
oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9 and, based on total composition
weight, from about 1% to about 25% of an aluminum salt
antiperspirant active.
18. A body wash/shampoo comprising a perfume according to any of
claims 1-8, 28-30, an encapsulate according to claim 25, a cyclic
oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9 and a miscellar phase and/or lamellar
phase.
19. A lotion comprising a perfume according to any of claims 1-8,
28-30, an encapsulate according to claim 25, a cyclic
oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9 and a humectant.
20. A lotion according to claim 19, said lotion comprising
glycerin.
21. A fabric care composition comprising a perfume according to any
of claims 1-8, 28-30, an encapsulate according to claim 25, a
cyclic oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9, said fabric care composition being
selected from the group consisting of detergents, fabric softeners,
and laundry additives, a) said detergent being: (i) a liquid
detergent comprising a material selected from an anti-redep
polymer, an enzyme, a structurant and mixtures thereof; (ii) a
powder or granule detergent comprising a material selected from the
group consisting of an anti-redep polymer, an enzymes, a bleach and
mixtures thereof; (iii) a unit dose comprising a material selected
from the group consisting of an anti-redep polymer, an enzymes, a
bleach, a soluble substrate/film and mixtures thereof b) said
fabric softener being a liquid, powder or sheet comprising a fabric
softener active and an optional structurant; c) said laundry
additive being: (i) a bleach additive comprising a material
selected from the group consisting of hypochlorite, hydrogen
peroxide and mixtures thereof; (ii) a pretreater comprising a
material selected from the group consisting of an effervescent, a
propellant and mixtures thereof; and (iii) an in-wash boosters
comprising a material selected from the group consisting of an
enzyme, a non-chlorine bleach and mixtures thereof.
22. A home care composition comprising a perfume according to any
of claims 1-8, 28-30, an encapsulate according to claim 25, a
cyclic oligosaccharide complex according to 26 and/or a perfume raw
material according to claim 9, said home care composition being
selected from the group consisting of an automatic dish washing
composition, a hand dish washing composition, a hard surface
cleaning composition and an air care composition, a) said automatic
dish washing composition being: (i) a liquid or gel comprising a
material selected from an anti-redep polymer, an enzyme, a
structurant, a shine/sheeting polymer and mixtures thereof; (ii) a
powder or granule comprising a material selected from the group
consisting of an anti-redep polymer, an enzyme, a bleach, a
shine/sheeting polymer and mixtures thereof; (iii) a unit dose
comprising a material selected from the group consisting of an
anti-redep polymer, an enzymes, a bleach, a shine/sheeting polymer,
a soluble substrate/film and mixtures thereof b) said hand dish
washing composition comprising a material selected from the group
consisting of a anti-bacterial, a hand/skin softener,
shine/sheeting polymers and mixtures thereof; c) said hard surface
cleaning composition comprising a material selected from the group
consisting of an anti-bacterial, a strong acid, preferably selected
from the group consisting of glycolic acid, citric acid and
mixtures thereof, etc., a strong base, preferably selected from the
group consisting of a Na hydroxides, a Li hydroxide and mixtures
thereof, an effervescent, a propellants, a shine/sheeting polymers
and mixtures thereof; d) an air care composition comprising a
malodor control composition that comprises zinc, cyclodextrin, a
propellant and/or mixtures thereof.
23. An air care device comprising one chamber, said chamber
comprising a perfume according to claims 1-8, 28-30, a perfume raw
material according to claim 9 and mixtures thereof.
24. An air care device comprising more than one chamber, one of
said chambers comprising a perfume according to claims 1-8, 28-30,
a perfume raw material according to claim 9 and mixtures
thereof.
25. An encapsulate comprising a shell and a core, said shell
encapsulating said core and said core comprising a perfume
according to any of claims 1-8, 28-30 and/or a perfume raw material
according to claim 9.
26. A cyclic oligosaccharide complex comprising a beta-cyclodextrin
that is complexed with a perfume according to any of claims 1-8,
28-30 and/or a perfume raw material according to claim 9.
27. A method of reducing fragrance habituation comprising
optionally washing and/or rinsing a situs, contacting said situs
with a perfume according to any of claims 1-8, and/or a perfume raw
material according to claim 9, a composition according to claims
10-22, a delivery system of claim 23 and/or a delivery system of
claim 24 and optionally washing and/or rinsing and/or drying said
situs.
28. A perfume composition according to claim 1 further comprising,
a) a fragrance component present in an amount of from about 1 wt %
to about 30 wt %, relative to the total weight of the composition;
and wherein: (i) the fragrance component comprises at least one low
volatile fragrance material having a vapor pressure less than 0.001
Torr; and (ii) the low volatile fragrance material is present in an
amount of from about 0.1 wt % to about 30 wt % relative to the
total weight of the fragrance component; b) at least one
non-odorous fragrance modulator formed of an alkoxylated methyl
glucoside selected from the group consisting of methyl glucoside
polyol, ethyl glucoside polyol, and propyl glucoside polyol,
preferably PPG-20 Methyl Glucose Ether, in an amount of from about
0.1 wt % to about 20 wt % relative to the total weight of the
composition.
29. A perfume composition according to claim 1, comprising a
perfume raw material selected from the group consisting of: a. a
perfume raw material comprising a sulfide moiety, preferably said
perfume raw material comprising a sulfide moiety is selected from
the group consisting of 1-butylsulfanylbutane,
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane, and
2-methyl-3-methylsulfanylpyrazine and mixtures thereof; b. a
perfume raw material comprising a thiazole moiety, preferably said
material comprising a thiazole moiety is selected from the group
consisting of 1-(1,3-thiazol-2-yl)ethanone; c. a perfume raw
material comprising a pyrazine moiety and acetyl moiety, preferably
said material comprising a pyrazine moiety and acetyl moiety is
selected from the group consisting of 1-pyrazin-2-ylethanone; d. a
perfume raw material comprising an oxime moiety, preferably said
material comprising an oxime moiety is selected from the group
consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and e. mixtures thereof.
30. A perfume composition according to claim 1, wherein said one or
more of said perfume raw materials are below their respective odor
detection thresholds.
Description
FIELD OF INVENTION
[0001] The present application relates to perfume raw materials,
perfumes, perfume delivery systems and consumer products comprising
such perfume raw materials, perfumes and/or such perfume delivery
systems, as well as processes for making and using such perfume raw
materials, perfumes, perfume delivery systems and consumer
products.
BACKGROUND OF THE INVENTION
[0002] Consumer products may comprise one or more perfumes and/or
perfume delivery systems that can provide a desired scent to such
product and/or a situs that is contacted with such a product and/or
mask an undesirable odor. While current perfumes and perfume
delivery systems provide desirable odors, consumers continue to
seek products that have scents that may be longer lasting and that
are tailored to their individual desires--unfortunately consumers
become habituated to perfume raw materials (PRMs) and perfumes. As
a result, ever increasing amounts of such PRMs and/or perfumes are
required to achieve the same effect or the consumer must switch to
a different product and/or perfume for a significant period of time
to reverse such habituation.
[0003] While not being bound by theory, Applicants believe that
habituation is a phenomenon that is grounded in the consumer's
physiology, in that the body is attempting to avoid having its
sense smell from being overwhelmed by any one stimulus after
repeated chronic exposure of said stimulus. This defense mechanism
is likely a primal, darwanistic defense mechanism. In short,
Applicants recognized that the source of habituation problem likely
laid in evolution. As a result, Applicants looked to odors that may
be associated with danger as Applicants believed that the
evolutionary path of those who became habituated to such odors
would have been cut short. Surprisingly, Applicants found that
certain chemical moieties that are associated with conditions that
may be detrimental to or important in sustaining life, are not
subject to the habituation phenomenon. Based on this recognition,
Applicants identified perfume raw materials, and developed
perfumes, perfume delivery systems and consumer products comprising
such perfume raw materials, perfumes and/or such perfume delivery
systems, as well as processes for making and using such perfume raw
materials, perfume delivery systems and consumer products that are
not as susceptible to habituation.
SUMMARY OF THE INVENTION
[0004] The present application relates to perfume raw materials,
perfumes, perfume delivery systems and consumer products comprising
such perfume raw materials, perfumes and/or such perfume delivery
systems, as well as processes for making and using such perfume raw
materials, perfume delivery systems and consumer products.
BRIEF DESCRIPTION OF THE DRAWINGS
[0005] It is believed that at least one aspect of the present
invention will be better understood from the following description
taken in conjunction with the accompanying drawings in which:
[0006] FIG. 1 is a partially fragmented schematic front view
showing one non-limiting embodiment of a device for emitting
volatile compositions.
[0007] FIG. 2 is a partially fragmented schematic side view of the
device shown in FIG. 1.
[0008] FIG. 3 is a schematic top view of the device shown in FIG.
1, showing the same adjacent to the cover plate of an electrical
outlet.
DETAILED DESCRIPTION OF THE INVENTION
Definitions
[0009] As used herein "consumer product" means baby care, beauty
care, fabric & home care, family care, feminine care, health
care, snack and/or beverage products, packaging or devices
generally intended to be used or consumed in the form in which it
is sold. Such products include but are not limited to diapers,
bibs, wipes; products for and/or methods relating to treating hair
(human, dog, and/or cat), including, bleaching, coloring, dyeing,
conditioning, shampooing, styling; deodorants and antiperspirants;
personal cleansing; cosmetics; skin care including application of
creams, lotions, and other topically applied products for consumer
use including fine fragrances; and shaving products, products for
and/or methods relating to treating fabrics, hard surfaces and any
other surfaces in the area of fabric and home care, including: air
care including air fresheners and scent delivery systems, car care,
dishwashing, fabric conditioning (including softening and/or
freshening), laundry detergency, laundry and rinse additive and/or
care, hard surface cleaning and/or treatment including floor and
toilet bowl cleaners, and other cleaning for consumer or
institutional use; products and/or methods relating to bath tissue,
facial tissue, paper handkerchiefs, and/or paper towels; tampons,
feminine napkins; products and/or methods relating to oral care
including toothpastes, tooth gels, tooth rinses, denture adhesives,
tooth whitening; over-the-counter health care including cough and
cold remedies, pain relievers, RX pharmaceuticals, pet health and
nutrition; processed food products intended primarily for
consumption between customary meals or as a meal accompaniment
(non-limiting examples include potato chips, tortilla chips,
popcorn, pretzels, corn chips, cereal bars, vegetable chips or
crisps, snack mixes, party mixes, multigrain chips, snack crackers,
cheese snacks, pork rinds, corn snacks, pellet snacks, extruded
snacks and bagel chips); and coffee.
[0010] As used herein, the term "cleaning and/or treatment
composition" is a subset of consumer products that includes, unless
otherwise indicated, beauty care, fabric & home care products.
Such products include, but are not limited to, products for
treating hair (human, dog, and/or cat), including, bleaching,
coloring, dyeing, conditioning, shampooing, styling; deodorants and
antiperspirants; personal cleansing; cosmetics; skin care including
application of creams, lotions, and other topically applied
products for consumer use including fine fragrances; and shaving
products, products for treating fabrics, hard surfaces and any
other surfaces in the area of fabric and home care, including: air
care including air fresheners and scent delivery systems, car care,
dishwashing, fabric conditioning (including softening and/or
freshening), laundry detergency, laundry and rinse additive and/or
care, hard surface cleaning and/or treatment including floor and
toilet bowl cleaners, granular or powder-form all-purpose or
"heavy-duty" washing agents, especially cleaning detergents;
liquid, gel or paste-form all-purpose washing agents, especially
the so-called heavy-duty liquid types; liquid fine-fabric
detergents; hand dishwashing agents or light duty dishwashing
agents, especially those of the high-foaming type; machine
dishwashing agents, including the various tablet, granular, liquid
and rinse-aid types for household and institutional use; liquid
cleaning and disinfecting agents, including antibacterial hand-wash
types, cleaning bars, mouthwashes, denture cleaners, dentifrice,
car or carpet shampoos, bathroom cleaners including toilet bowl
cleaners; hair shampoos and hair-rinses; shower gels, fine
fragrances and foam baths and metal cleaners; as well as cleaning
auxiliaries such as bleach additives and "stain-stick" or pre-treat
types, substrate-laden products such as dryer added sheets, dry and
wetted wipes and pads, nonwoven substrates, and sponges; as well as
sprays and mists all for consumer or/and institutional use; and/or
methods relating to oral care including toothpastes, tooth gels,
tooth rinses, denture adhesives, tooth whitening.
[0011] As used herein, the term "fabric and/or hard surface
cleaning and/or treatment composition" is a subset of cleaning and
treatment compositions that includes, unless otherwise indicated,
granular or powder-form all-purpose or "heavy-duty" washing agents,
especially cleaning detergents; liquid, gel or paste-form
all-purpose washing agents, especially the so-called heavy-duty
liquid types; liquid fine-fabric detergents; hand dishwashing
agents or light duty dishwashing agents, especially those of the
high-foaming type; machine dishwashing agents, including the
various tablet, granular, liquid and rinse-aid types for household
and institutional use; liquid cleaning and disinfecting agents,
including antibacterial hand-wash types, cleaning bars, car or
carpet shampoos, bathroom cleaners including toilet bowl cleaners;
and metal cleaners, fabric conditioning products including
softening and/or freshening that may be in liquid, solid and/or
dryer sheet form; as well as cleaning auxiliaries such as bleach
additives and "stain-stick" or pre-treat types, substrate-laden
products such as dryer added sheets, dry and wetted wipes and pads,
nonwoven substrates, and sponges; as well as sprays and mists. All
of such products which were applicable may be in standard,
concentrated or even highly concentrated form even to the extent
that such products may in certain aspect be non-aqueous.
[0012] As used herein, articles such as "a" and "an" when used in a
claim, are understood to mean one or more of what is claimed or
described.
[0013] As used herein, the terms "include", "includes" and
"including" are meant to be non-limiting.
[0014] As used herein, the term "solid" includes granular, powder,
bar and tablet product forms.
[0015] As used herein, the term "fluid" includes liquid, gel, paste
and gas product forms.
[0016] As used herein, the term "situs" includes paper products,
fabrics, garments, hard surfaces, hair and skin.
[0017] As used herein, the term "neat" when used in the context of
a perfume, means the perfume is not part of/contained in a perfume
delivery system.
[0018] The perfume raw materials disclosed, claimed and/or used in
the perfumes claimed and/or described herein encompass any
stereoisomers of such perfume raw materials.
[0019] As used herein, the term "habituating" refers an individual
or group who has decreased sensitivity to perceiving a fragrance or
fragrance material. A fragrance or fragrance material is considered
habituating when their Degree of Habituation (percent change in
ODT) is greater than 150%, greater than 300%, greater than 500%,
greater than 1000% according to the method described in the Test
Methods section of this specification.
[0020] Unless otherwise noted, all component or composition levels
are in reference to the active portion of that component or
composition, and are exclusive of impurities, for example, residual
solvents or by-products, which may be present in commercially
available sources of such components or compositions.
[0021] All percentages and ratios are calculated by weight unless
otherwise indicated. All percentages and ratios are calculated
based on the total composition unless otherwise indicated.
[0022] It should be understood that every maximum numerical
limitation given throughout this specification includes every lower
numerical limitation, as if such lower numerical limitations were
expressly written herein. Every minimum numerical limitation given
throughout this specification will include every higher numerical
limitation, as if such higher numerical limitations were expressly
written herein. Every numerical range given throughout this
specification will include every narrower numerical range that
falls within such broader numerical range, as if such narrower
numerical ranges were all expressly written herein.
Perfumes
[0023] In one aspect, a perfume comprising, based on total perfume
weight, a perfume raw material selected from the group consisting
of: [0024] a) from about 0.0000001% to about 10%, from about
0.000001% to about 5%, from about 0.000005% to about 2.5%, from
about 0.00001% to about 1%, from about 0.000025% to about 0.8%, of
a perfume raw material comprising a thiol moiety; [0025] b) from
about 0.0000001% to about 10%, from about 0.0000001% to about 5%,
from about 0.000005% to about 2.5%, from about 0.00001% to about
1%, from about 0.000025% to about 0.5%, of a perfume raw material
comprising a sulfide moiety; [0026] c) from about 0.000001% to
about 10%, from about 0.000005% to about 5%, from about 0.00001% to
about 2.5%, from about 0.0005% to about 1%, from about 0.001% to
about 0.1%, of a perfume raw material comprising a thiazole moiety;
[0027] d) from about 0.00000005% to about 5%, from about 0.0000001%
to about 2.5%, from about 0.0000005% to about 2%, from about
0.000001% to about 1%, from about 0.000005% to about 0.5%, of a
perfume raw material comprising a pyrazine moiety; [0028] e) from
about 0.00001% to about 20%, from about 0.0001% to about 15%, from
about 0.001% to about 10%, from about 0.01% to about 5%, from about
0.1% to about 2.5%, of a perfume raw material comprising a nitrile
moiety; [0029] f) from about 0.000001% to about 10%, from about
0.00001% to about 7%, from about 0.0001% to about 4%, from about
0.001% to about 2%, from about 0.01% to about 1%, of a perfume raw
material comprising an indole moiety; [0030] g) from about
0.0000001% to about 10%, from about 0.000001% to about 5%, from
about 0.000005% to about 2.5%, from about 0.00001% to about 1%,
from about 0.000025% to about 0.8%, of a perfume raw material
comprising an oxathiane moiety; [0031] h) from about 0.00001% to
about 10%, from about 0.0001% to about 7.5%, from about 0.001% to
about 5%, from about 0.005% to about 2.5%, from about 0.01% to
about 1%, of a perfume raw material comprising an oxime moiety;
[0032] i) from about 0.00001% to about 20%, from about 0.0001% to
about 15%, from about 0.001% to about 10%, from about 0.01% to
about 5%, from about 0.1% to about 2.5%, of a perfume raw material
comprising an amine moiety; [0033] j) from about 0.00000005% to
about 5%, from about 0.0000001% to about 2.5%, from about
0.0000005% to about 2%, from about 0.000001% to about 1%, from
about 0.000005% to about 0.5%, of a perfume raw material comprising
an isothiocyanate; [0034] k) from about 0.00000005% to about 5%,
from about 0.0000001% to about 2.5%, from about 0.0000005% to about
2%, from about 0.000001% to about 1%, from about 0.000005% to about
0.5%, of a perfume raw material comprising a diamine moiety; [0035]
l) from about 0.000001% to about 10%, from about 0.000005% to about
5%, from about 0.00001% to about 2.5%, from about 0.0005% to about
1%, from about 0.001% to about 0.1%, of a perfume raw material
comprising oxygen, sulfur, and nitrogen; and m) mixtures thereof,
with the proviso that the sum of the percentage of said perfume raw
materials cannot exceed 100%, is disclosed. [0036] In one aspect,
said perfume comprises, based on total perfume weight, a perfume
raw material selected from the group consisting of: items a), b)
c), d), g), h), j), k), l), m) and mixtures thereof.
[0037] In one aspect, said perfume comprises, based on total
perfume weight, a perfume raw material selected from the group
consisting of: items a), b) c), d), g), m) and mixtures
thereof.
[0038] In one aspect, of said perfume: [0039] a) said perfume raw
material comprising a thiol moiety is selected from the group
consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; methanethiol; Ethanethiol;
prop-2-ene-1-thiol; propane-2-thiol; 2-methylpropane-2-thiol;
propane-1-thiol; butane-2-thiol; butane-1-thiol;
2-methylpropane-1-thiol; methyldisulfanylmethane;
2-methylbutane-2-thiol; 3-methylbutane-2-thiol;
3-methylbutane-2-thiol; pentane-2-thiol; pentane-1-thiol;
2-methylbutane-1-thiol; cyclopentanethiol;
3-methyldisulfanylprop-1-ene; methylsulfanyldisulfanylmethane;
1-methyldisulfanylpropane; ethane-1,2-dithiol;
1-(methyldisulfanyl)prop-1-ene; 3-sulfanylbutan-2-one;
ethyldisulfanylethane; hexane-1-thiol; 1-ethyldisulfanylpropane;
thiophene-2-thiol; propane-1,3-dithiol; 3-sulfanylpentan-2-one;
2-propan-2-yldisulfanylpropane; butane-1,4-dithiol; benzenethiol;
ethylsulfanyldisulfanylethane;
3-methylsulfanyldisulfanylprop-1-ene;
1-methylsulfanyldisulfanylpropane; butane-2,3-dithiol;
4-methyl-4-sulfanylpentan-2-one; 3-prop-2-enyldisulfanylprop-1-ene;
1-methoxyhexane-3-thiol; ethyl 2-sulfanylpropanoate;
1-(prop-2-enyldisulfanyl)propane; 1-propyldisulfanylpropane;
1-(4-hydroxy-3-methoxyphenyl)ethanone butane-1,3-dithiol;
1-propyldisulfanylprop-1-ene; 2-methylbenzenethiol;
thiophen-2-ylmethanethiol; 3-sulfanylbutan-2-ol; phenylmethanethiol
pentane-1,5-dithiol; 2-ethylbenzenethiol;
3-prop-2-enylsulfanyldisulfanylprop-1-ene;
methyldisulfanyldisulfanylmethane;
1-propylsulfanyldisulfanylpropane;
2,7,7-trimethylbicyclo[3.1.1]heptane-2-thiol;
2,6-dimethylbenzenethiol; 2-phenylethanethiol; hexane-1,6-dithiol;
2-(methyldisulfanylmethyl)furan; pyridin-2-ylmethanethiol;
2-methoxybenzenethiol;
(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)methanethiol;
methyldisulfanylbenzene; 1-butyldisulfanylbutane;
(4-methoxyphenyl)methanethiol; 2-sulfanylpropanoic acid; ethyl
2-methyldisulfanylpropanoate;
(2E)-3,7-dimethylocta-2,6-diene-1-thiol;
3,7-dimethylocta-2,6-diene-1-thiol; pyrazin-2-ylmethanethiol;
methyldisulfanylmethylbenzene;
2-methyl-5-(1-sulfanylpropan-2-yl)cyclohexane-1-thiol;
octane-1,8-dithiol; 2-pyrazin-2-ylethanethiol; naphthalene-2-thiol;
2-oxo-3-sulfanylpropanoic acid; 2-thiophen-2-yldisulfanylthiophene;
cyclohexyldisulfanylcyclohexane;
2-(furan-2-ylmethyldisulfanylmethyl)furan; phenyldisulfanylbenzene;
benzyldisulfanylmethylbenzene; 8-Hydroxy-5-quinolinesulfonic acid;
bis(3-methylbutyl) 2-sulfanylbutanedioate; 2-aminoethanesulfonic
acid; 2-phenyl-3H-benzimidazole-5-sulfonic acid;
2-methyl-2-sulfanylpentan-1-ol; and mixtures thereof; [0040] b)
said perfume raw material comprising a sulfide moiety is selected
from the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan;
methylsulfanylmethane; methylsulfanylethane;
3-methylsulfanylprop-1-ene; S-methyl ethanethioate;
ethylsulfanylethane; 1-methylsulfanylpropane; S-ethyl
ethanethioate; 1-methylsulfanylbutane;
2-propan-2-ylsulfanylpropane; bis(methylsulfanyl)methane;
1-ethylsulfanylpropane; thiolane; 1-propylsulfanylpropane;
1-ethylsulfanylbutane; S-ethyl propanethioate; S-methyl
butanethioate; S-methyl 3-methylbutanethioate;
3-methylsulfanylpropanal; 3-prop-2-enylsulfanylprop-1-ene; methyl
2-methylsulfanylacetate; S-prop-2-enyl propanethioate;
1-methylsulfanylbutan-2-one; 4-methylsulfanylbutan-2-one;
3-methylsulfanylpropan-1-am; 2,4,6-trimethyl-1,3,5-trithiane;
3-methylsulfanylbutanal; 2-methyl-1,3-thiazolidine;
2-methyl-4,5-dihydro-1,3-thiazole; ethyl 2-methylsulfanylacetate;
methyl 3-methylsulfanylpropanoate; S-propan-2-yl
3-methylbutanethioate; 4-methyl-4-methylsulfanylpentan-2-one;
2-methyl-1,3-dithiolane; methyl 2-methylsulfanylbutanoate; S-methyl
furan-2-carbothioate; S-propan-2-yl 3-methylbut-2-enethioate;
thiolan-3-one; 3,5-diethyl-1,2,4-trithiolane;
methylsulfanylmethylbenzene; 3-methylsulfanylpropan-1-ol;
2-(propan-2-ylsulfanylmethyl)furan; 2-methyl-5-methylsulfanylfuran;
S-(furan-2-ylmethyl) methanethioate; 1,2,4-trithiolane;
2-methylthiolan-3-one; 4-methylsulfanylbutan-1-ol; S-butan-2-yl
3-methylbutanethioate; S-butan-2-yl 3-methylbut-2-enethioate;
S-(furan-2-ylmethyl)ethanethioate; 2-propyl-1,3-thiazolidine;
3-methyl-1,1-bis(methylsulfanyl)butane; 3-ethylsulfanylpropan-1-ol;
S-methyl benzenecarbothioate; 3,5-dimethyl-1,2,4-trithiolane;
S-butan-2-yl 2-methylbutanethioate; methylsulfanylbenzene;
1-pentylsulfanylpentane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-methyl-4-propyl-1,3-oxathiane; ethyl
2-methyl-2-methylsulfanylpropanoate; S-(furan-2-ylmethyl)
propanethioate; 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
3-methyl-1,2,4-trithiane; methylsulfanylmethyl hexanoate;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone; 3-methylsulfanylpropanoic
acid; 5-methylsulfanyl-2-(methylsulfanylmethyl)pent-2-enal;
4,5-dimethyl-2-(2-methylpropyl)-2,5-dihydro-1,3-thiazole;
3-methylsulfanylhexan-1-ol; 2-methyl-4,5-dihydrofuran-3-thiol
acetate; 4-(3-oxobutylsulfanyl)butan-2-one;
3-methylsulfanylbutanoic acid; 2-methylsulfanylpyrazine;
2-methyl-3-methylsulfanylpyrazine;
2-(furan-2-ylmethylsulfanylmethyl)furan;
2-(methylsulfanylmethyl)pyrazine;
3,5-di(propan-2-yl)-1,2,4-trithiolane; 2-methylsulfanylphenol;
2-methyl-3-methylsulfanylpyrazine; ethyl
3-(furan-2-ylmethylsulfanyl)propanoate;
2,2,4,4,6,6-hexamethyl-1,3,5-trithiane;
2-methyl-5,7-dihydrothieno[3,4-d]pyrimidine;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolan-
e]; 2,5-dimethyl-1,4-dithiane-2,5-diol; Methyl 2-thiofuroate and
mixtures thereof; [0041] c) said perfume raw material comprising a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
2,4,5-Trimethylthiazole; 2-isopropyl-4-methylthiazole;
4-vinyl-5-methylthiazole; 2,4-Dimethyl-5-acetylthiazole
1,3-thiazole; 4-methyl-1,3-thiazole; 2,4-dimethyl-1,3-thiazole;
4,5-dimethyl-1,3-thiazole; 2,5-dimethyl-1,3-thiazole;
5-ethenyl-4-methyl-1,3-thiazole; 2-ethyl-4-methyl-1,3-thiazole;
4-ethyl-2-methyl-1,3-thiazole; 2-propyl-1,3-thiazole;
2,4,5-trimethyl-1,3-thiazole; 2-ethyl-1,3-thiazole;
2-ethoxy-1,3-thiazole; 2-butan-2-yl-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole; 2-ethyl-4,5-dimethyl-1,3-thiazole;
1,3-benzothiazole; 2,5-diethyl-4-methyl-1,3-thiazole;
1-(1,3-thiazol-2-yl)propan-1-one;
4,5-dimethyl-2-(2-methylpropyl)-1,3-thiazole;
2-methyl-1,3-benzothiazole;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
4-methyl-2-propan-2-yl-1,3-thiazole; and mixtures thereof; [0042]
d) said perfume raw material comprising a pyrazine moiety is
selected from the group consisting of
2-methoxy-3-(2-methylpropyl)pyrazine; 2,3-dimethylpyrazine;
1-pyrazin-2-ylethanone; 2-methyl-3-methylsulfanylpyrazine;
Pyrazine; 2-methylpyrazine; 2-ethenylpyrazine; 2-ethylpyrazine;
2,6-dimethylpyrazine; 2,5-dimethylpyrazine;
2-prop-1-en-2-ylpyrazine; 2-propan-2-ylpyrazine; 2-methoxypyrazine;
2-ethenyl-5-methylpyrazine; 2-ethyl-5-methylpyrazine;
2-Ethyl-6-methylpyrazine; 2-Ethyl-3-Methyl-Pyrazine;
2-propylpyrazine; 2,3,5-trimethylpyrazine; 2-tert-butylpyrazine;
pyrazin-2-amine; 2-(2-methylpropyl)pyrazine;
2-methyl-5-propan-2-ylpyrazine; 2-(methoxymethyl)pyrazine;
2,3-diethylpyrazine; 2-ethyl-3,(5 OR 6)-dimethylpyrazine;
2-ethyl-3,5-dimethylpyrazine; 3-ethyl-2,5-dimethylpyrazine;
3-ethyl-2,5-dimethylpyrazine; 2-ethyl-3,5-dimethylpyrazine;
2-methyl-3-propylpyrazine; 2,3,5,6-tetramethylpyrazine;
7-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine;
2-methylsulfanylpyrazine; 2-methyl-3-methylsulfanylpyrazine;
2-ethoxy-3-ethylpyrazine; 2-Isobutyl-3-methylpyrazine;
pyrazin-2-ylmethanethiol; 3,5-dimethyl-2-propylpyrazine;
2-ethyl-3-methoxypyrazine; 2-ethoxy-3-methylpyrazine;
2-ethyl-5-methoxypyrazine; 5,6,7,8-tetrahydroquinoxaline;
2-ethoxy-3-propan-2-ylpyrazine; 2-(methylsulfanylmethyl)pyrazine;
3,5-dimethyl-2-(2-methylpropyl)pyrazine;
2,3-diethyl-5-methylpyrazine; 3,5-Diethyl-2-methylpyrazine;
2,5-dimethyl-3-(2-methylpropyl)pyrazine;
2-methyl-6-propoxypyrazine; 2-(2-methylpropoxy)pyrazine;
1-(3-methylpyrazin-2-yl)ethanone;
2-methyl-3-methylsulfanylpyrazine; 2-methoxy-3-propan-2-ylpyrazine;
quinoxaline; 3-butyl-2,5-dimethylpyrazine;
2-butyl-3,5-dimethylpyrazine; 2-pyrazin-2-ylethanethiol;
1-(3-ethylpyrazin-2-yl)ethanone;
1-(3,5-dimethylpyrazin-2-yl)ethanone;
2-butan-2-yl-3-methoxypyrazine; 2-methylquinoxaline;
5-Methylquinoxaline; 2-methoxy-3-(4-methylpentyl)pyrazine;
2,3-dimethylquinoxaline; 2-(cyclohexylmethyl)pyrazine;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine and mixtures
thereof; [0043] e) said perfume raw material comprising a nitrile
moiety is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
[0044] f) said perfume raw material comprising a indole moiety is
selected from the group consisting of 1H-indole,
3-methyl-1H-indole; and mixtures thereof; [0045] g) said perfume
raw material comprising a oxathiane moiety is selected from the
group consisting of (2R,4S)-2-methyl-4-propyl-1,3-oxathiane,
2-methyl-4-propyl-1,3-oxathiane, 2-pentyl-4-propyl-1,3-oxathiane;
and mixtures thereof; [0046] h) said perfume raw material
comprising a oxime moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
N-(5-methylheptan-3-ylidene)hydroxylamine, and mixtures thereof;
[0047] i) said perfume raw material comprising an amine moiety is
selected from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine; 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof;
[0048] In one aspect of said perfume, said perfume raw material
comprises at least one sulfur, oxygen and nitrogen atom, said
perfume raw material being selected from the group consisting of
2-(4-methyl-1,3-thiazol-5-yl)ethanol; 1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine;
2,4-Dimethyl-5-acetylthiazole; 2-ethoxy-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone;
1-(1,3-thiazol-2-yl)propan-1-one;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
8-Hydroxy-5-quinolinesulfonic acid; 2-aminoethanesulfonic acid;
2-phenyl-3H-benzimidazole-5-sulfonic acid; and mixtures
thereof.
[0049] In one aspect of said perfume: [0050] a) said perfume raw
material comprises a thiol moiety is selected from the group
consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; and mixtures thereof; [0051] b)
said perfume raw material comprises a sulfide moiety is selected
from the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan; and
mixtures thereof; [0052] c) said perfume raw material comprises a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
and mixtures thereof; [0053] d) said perfume raw material comprises
a pyrazine moiety is selected from the group consisting of
2-methoxy-3-(2-methylpropyl)pyrazine; 2,3-dimethylpyrazine;
1-pyrazin-2-ylethanone; 2-methyl-3-methylsulfanylpyrazine; and
mixtures thereof; [0054] e) said perfume raw material comprises a
nitrile moiety is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
[0055] f) said perfume raw material comprises a indole moiety is
selected from the group consisting of 1H-indole. [0056] g) said
perfume raw material comprises a oxathiane moiety is selected from
the group consisting of (2R,4S)-2-methyl-4-propyl-1,3-oxathiane.
[0057] h) said perfume raw material comprises a oxime moiety is
selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine.
[0058] i) said perfume raw material comprises a amine moiety is
selected from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine, 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof; [0059] j) said perfume raw material comprises
oxygen, sulfur, and nitrogen is selected from the group consisting
of 2-(4-methyl-1,3-thiazol-5-yl)ethanol,
1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane; and mixtures
thereof.
[0060] In one aspect of said perfume, said perfume raw material
comprises a perfume raw material selected from the group consisting
of: [0061] a) 1-butylsulfanylbutane;
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane; and
4-methoxy-2-methylbutane-2-thiol; [0062] b)
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and 7-hydroxy-3,7-dimethyloctanal;
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; [0063] c)
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
7-Oxa-1-thia-4-azaspiro[4.4]nonane; and 6-methyl-,
1-(1,3-thiazol-2-yl)ethanone; [0064] d)
2-methoxy-3-(2-methylpropyl)pyrazine; 1-pyrazin-2-ylethanone; and
2,3-dimethylpyrazine; [0065] e) 2-(methylsulfanylmethyl)furan;
ethyl 3-methylsulfanylpropanoate; and 1-butylsulfanylbutane; [0066]
f) 5-methyl-5-sulfanylhexan-3-one;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one; and
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; [0067] g)
2-methoxy-3-(2-methylpropyl)pyrazine; 3,7-dimethyloct-6-enenitrile;
and methyl 2-aminobenzoate; [0068] h)
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol; and
4-methyl-2-propan-2-yl-1,3-thiazole; [0069] i)
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; and
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and [0070] j) mixtures thereof.
[0071] In one aspect of said perfume composition, said composition
comprises a perfume raw material selected from the group consisting
of: [0072] a) a perfume raw material comprising a sulfide moiety,
in one aspect, said perfume raw material comprising a sulfide
moiety is selected from the group consisting of
1-butylsulfanylbutane, 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane,
and 2-methyl-3-methylsulfanylpyrazine and mixtures thereof; [0073]
b) a perfume raw material comprising a thiazole moiety, in one
aspect, said material comprising a thiazole moiety is selected from
the group consisting of 1-(1,3-thiazol-2-yl)ethanone; [0074] c) a
perfume raw material comprising a pyrazine moiety and acetyl
moiety, in one aspect, said material comprising a pyrazine moiety
and acetyl moiety is selected from the group consisting of
1-pyrazin-2-ylethanone; [0075] d) a perfume raw material comprising
an oxime moiety, in one aspect, said material comprising an oxime
moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and [0076] e) mixtures thereof.
[0077] In one aspect, a perfume having:
[0078] a) a two week anti-habituation index of at least 0, 1, 2, 3
or 4;
[0079] b) a four week anti-habituation index of at least 0, 1, 2,
3, or 4;
[0080] c) a two week anti-habituation index of 0, 1, 2, 3 or 4;
and/or
[0081] d) a four week anti-habituation index of 0, 1, 2, 3 or 4
is disclosed. [0082] In one aspect, said perfume composition may
contain a fragrance modulator. Fragrance modulators enhance
intensity of a fragrance profile over time, preferably so that the
volatile fragrance materials remain significantly consistent from
its initial impression to the end. Fragrance modulators are
disclosed in U.S. Provisional Patent Ser. No. 61/915,514 which is
incorporated by reference. Thus, in one aspect, said perfume
composition comprises: [0083] a) a fragrance component present in
an amount of from about 1 wt % to about 30 wt %, preferably less
than about 20 wt %, preferably less than about 15 wt %, preferably
less than about 10 wt % or preferably less than 8 wt %, relative to
the total weight of the composition; and wherein: [0084] (i) the
fragrance component comprises at least one low volatile fragrance
material having a vapor pressure less than 0.001 Torr; and [0085]
(ii) the low volatile fragrance material is present in an amount of
from about 0.1 wt % to about 30 wt %, preferably less than about 25
wt %, preferably less than about 20 wt %, or preferably less than
about 12 wt %, relative to the total weight of the fragrance
component; [0086] b) at least one non-odorous fragrance modulator
formed of an alkoxylated methyl glucoside selected from the group
consisting of methyl glucoside polyol, ethyl glucoside polyol, and
propyl glucoside polyol, preferably PPG-20 Methyl Glucose Ether, in
an amount of from about 0.1 wt % to about 20 wt %, preferably about
0.5 wt % to about 18 wt %, or more preferably about 2.5 wt % to
about 15%, relative to the total weight of the composition.
[0087] In one aspect, said low volatile fragrance material is
selected from the group consisting of: 2-Buten-1-ol,
2-methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-; Ethanone,
1-(2-naphthalenyl)-; 3-Decanone, 1-hydroxy-; Cyclopropanemethanol,
1-methyl-2-[(1,2,2-trimethylbicyclo[3.1.0]hex-3-yl)methyl]-;
Benzaldehyde, 3-ethoxy-4-hydroxy-; 2H-1,5-Benzodioxepin-3(4H)-one,
7-methyl-; 2-Butanol, 1-[[2-(1,1-dimethylethyl)cyclohexyl]oxy]-;
Spiro[5.5]undec-8-en-1-one, 2,2,7,9-tetramethyl-;
Cyclopentaneacetic acid, 3-oxo-2-pentyl-, methyl ester,
(1R,2R)-rel-; Cyclopentaneacetic acid, 3-oxo-2-pentyl-, methyl
ester; Octanal, 2-(phenylmethylene)-; Indeno[4,5-d]-1,3-dioxin,
4,4a,5,6,7,8,9,9b-octahydro-7,7,8,9,9-pentamethyl-;
Cyclopentanecarboxylic acid, 2-hexyl-3-oxo-, methyl ester;
3-Cyclopentene-1-butanol, .alpha.,.beta.,2,2,3-pentamethyl-;
Cyclopentanone, 2-(3,7-dimethyl-2,6-octadien-1-yl)-;
1,6,10-Dodecatrien-3-ol, 3,7,11-trimethyl-; 2-Pentenenitrile,
3-methyl-5-phenyl-, (2Z)--; Benzenepropanenitrile,
4-ethyl-.alpha.,.alpha.-dimethyl-; 1H-3a,7-Methanoazulen-6-ol,
octahydro-3,6,8,8-tetramethyl-, (3R,3aS,6R,7R,8aS)-; Ethanone,
1-(1,2,3,5,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)-;
Ethanone,
1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl-
)-; Propanoic acid, 2-methyl-, 4-formyl-2-methoxyphenyl ester;
1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-;
Benzoic acid, 2-hydroxy-, hexyl ester; Benzoic acid, phenyl ester;
Cyclohexanepropanol, 2,2,6-trimethyl-.alpha.-propyl-, (1R,6S)--;
Cyclohexanepropanol, 2,2,6-trimethyl-.alpha.-propyl-; Benzoic acid,
2-hydroxy-, 3-methyl-2-buten-1-yl ester;
2H-1,5-Benzodioxepin-3(4H)-one, 7-(1-methylethyl)-; Butanal,
4-(octahydro-4,7-methano-5H-inden-5-ylidene)-;
Cyclopenta[g]-2-benzopyran,
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-; Cyclopentanone,
2-[2-(4-methyl-3-cyclohexen-1-yl)propyl]-; 2(3H)-Naphthalenone,
4,4a,5,6,7,8-hexahydro-4,4-.alpha.-dimethyl-6-(1-methylethenyl)-,
(4R,4aS,6R)--; 2-Propenoic acid, 3-phenyl-, pentyl ester;
4H-Pyran-4-one, 3-hydroxy-2-methyl-; 1-Propanol,
2-methyl-3-[(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)oxy]-;
1-Naphthalenol,
1,2,3,4,4a,5,8,8.alpha.-octahydro-2,2,6,8-tetramethyl-; 2-Butenoic
acid, 2-methyl-, (2E)-3,7-dimethyl-2,6-octadien-1-yl ester, (2E)-;
1,3-Dioxane,
2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)-;
4-Penten-2-ol, 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-;
Propanoic acid, 2-methyl-, 2-methyl-4-oxo-4H-pyran-3-yl ester;
2-Buten-1-ol, 2-ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-;
1,6-Methanonaphthalen-1 (2H)-ol, octahydro-4,8a,9,9-tetramethyl-,
(1R,4S,4aS,6R,8aS)-; 2H-1,5-Benzodioxepin-3(4H)-one,
7-(1,1-dimethylethyl)-; Benzoic acid, phenylmethyl ester;
8-Cyclohexadecen-1-one; Benzoic acid, 2-hydroxy-, (3Z)-3-hexen-1-yl
ester; 4H-Pyran-4-one, 2-ethyl-3-hydroxy-; Cyclopentadecanone,
3-methyl-; Benzoic acid, 2-hydroxy-, phenylmethyl ester;
6,8-Nonadien-3-one, 2,4,4,7-tetramethyl-, oxime; Benzoic acid,
2-hydroxy-, cyclohexyl ester; Benzene,
[2-(dimethoxymethyl)-1-hepten-1-yl]-; 3-Cyclopentene-1-butanol,
.beta.,2,2,3-tetramethyl-.delta.-methylene-; 4-Penten-1-one,
1-spiro[4.5]dec-7-en-7-yl-; Acetic acid, 2-(1-oxopropoxy)-,
1-(3,3-dimethylcyclohexyl)ethyl ester; 4-Penten-2-ol,
3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-;
5,8-Methano-2H-1-benzopyran-2-one, 6-ethylideneoctahydro-;
4-Cyclopentadecen-1-one, (4Z)--; Ethanone,
1-[(3R,3aR,7R,8aS)-2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-met-
hanoazulen-5-yl]-; 1,3-Dioxolane,
2,4-dimethyl-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-;
Oxacyclohexadecan-2-one; 1-Propanol,
2-[1-(3,3-dimethylcyclohexyl)ethoxy]-2-methyl-, 1-propanoate;
5-Cyclopentadecen-1-one, 3-methyl-; 2H-1,5-Benzodioxepin-3(4H)-one,
7-(3-methylbutyl)-; Ethanone,
1-(2,6,10-trimethyl-2,5,9-cyclododecatrien-1-yl)-;
1H-3a,6-Methanoazulene-3-methanol,
octahydro-7,7-dimethyl-8-methylene-, (3S,3aR,6R,8aS)-;
Benzeneacetonitrile, .alpha.-cyclohexylidene-; Benzoic acid,
2-[(2-methylpentylidene)amino]-, methyl ester; Benzoic acid,
2-phenylethyl ester; Cyclohexanol,
4-(1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)-;
3-Cyclohexene-1-carboxaldehyde, 4-(4-hydroxy-4-methylpentyl)-;
Ethanone, 1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-;
2-Cyclopentadecen-1-one, 3-methyl-; Oxacycloheptadecan-2-one;
Benzeneacetic acid, 4-methylphenyl ester; Benzeneacetic acid,
2-phenylethyl ester; Cyclododecaneethanol, .beta.-methyl-;
2-Propenoic acid, 3-phenyl-, phenylmethyl ester; Benzoic acid,
2,4-dihydroxy-3,6-dimethyl-, methyl ester;
Naphtho[2,1-b]furan-6(7H)-one, 8,9-dihydro-1,5,8-trimethyl-,
(8R)--; Benzeneacetic acid, (4-methoxyphenyl)methyl ester; Benzene,
2-methoxy-1-(phenylmethoxy)-4-(1-propen-1-yl)-; Benzeneacetic acid,
(2E)-3,7-dimethyl-2,6-octadien-1-yl ester; Benzoic acid,
2-hydroxy-, 2-phenylethyl ester; 2-Propenoic acid, 3-phenyl-,
1-ethenyl-1,5-dimethyl-4-hexen-1-yl ester;
Oxacycloheptadec-10-en-2-one; Oxacycloheptadec-8-en-2-one, (8Z)--;
1,7-Dioxacycloheptadecan-8-one;
1,4-Dioxacyclohexadecane-5,16-dione;
1,4-Dioxacycloheptadecane-5,17-dione; Benzoic acid,
2-[(1-hydroxy-3-phenylbutyl)amino]-, methyl ester; and combinations
thereof.
[0088] In one aspect, said fragrance component comprises one or
more volatile fragrance materials, wherein: [0089] a) the volatile
fragrance material has a vapor pressure .gtoreq.0.001 Torr; [0090]
b) the volatile fragrance material is present in an amount of from
about 70 wt % to about 99.9 wt %, preferably greater than about 80
wt %, or most preferably greater than about 88%, relative to the
total weight of the fragrance component; and [0091] c) combinations
thereof. In one aspect, said volatile fragrance material is
selected from the group consisting of: [0092] a) a high volatile
fragrance material having a vapor pressure >0.1 Torr; [0093] b)
a moderate volatile fragrance material having a vapor pressure in
the range of 0.1 Torr to 0.001 Torr; and [0094] c) combinations
thereof. In one aspect, said volatile fragrance material is
selected from the group consisting of: Formic acid, methyl ester;
Methane, 1,1'-thiobis-; Acetic acid ethyl ester; Propanoic acid,
ethyl ester; Acetic acid, 2-methylpropyl ester; Butanoic acid,
ethyl ester; 1-Butanol; Butanoic acid, 2-methyl-, ethyl ester;
1-Butanol, 3-methyl-, 1-acetate; Butanoic acid, 2-methyl-,
1-methylethyl ester; 2-Heptanone; 2-Hexenal, (2E)-; 1-Butanol,
3-methyl-; 2-Buten-1-ol, 3-methyl-, 1-acetate;
1,3-Dioxolane-2-methanamine, N-methyl-; Bicyclo[3.1.1]hept-2-ene,
2,6,6-trimethyl-, (1R,5R)--; Bicyclo[2.2.1]heptane,
2,2-dimethyl-3-methylene-; 2-Butanethiol, 4-methoxy-2-methyl-;
Pentanoic acid, 2-methyl-, ethyl ester; Bicyclo[3.1.1]heptane,
6,6-dimethyl-2-methylene-; 1-Butanol, 3-methyl-, 1-propanoate;
1,6-Octadiene, 7-methyl-3-methylene-; Octanal; 2H-Pyran,
2-ethenyltetrahydro-2,6,6-trimethyl-; 2-Octanone; Hexanoic acid,
ethyl ester; 2-Oxabicyclo[2.2.2]octane, 1,3,3-trimethyl-; Benzene,
1-methyl-4-(1-methylethyl)-; Benzene, 1-methoxy-4-methyl-;
1,3,6-Octatriene, 3,7-dimethyl-; Cyclohexene,
1-methyl-4-(1-methylethenyl)-; Cyclohexene,
1-methyl-4-(1-methylethenyl)-, (4R)--; 3-Octanone; Undecanal,
2-methyl-; Acetic acid, hexyl ester; 5-Hepten-2-one, 6-methyl-;
2-Hepten-4-one, 5-methyl-; 3-Hexen-1-ol, 1-acetate, (3Z)--;
3-Hexen-1-ol, 1-acetate; Propanoic acid, 2-hydroxy-, ethyl ester;
Butanoic acid, 2-methylbutyl ester; Butanoic acid, 3-methylbutyl
ester; 1,4-Cyclohexadiene, 1-methyl-4-(1-methylethyl)-; Thiazole,
2-(2-methylpropyl)-; 3-Hexen-1-ol, (3Z)--; Benzaldehyde; Butanoic
acid, 3-oxo-, ethyl ester; 2-Hexen-1-ol, (2E)-; 2-Hexen-1-ol,
(2Z)--; Cyclohexane, 3-ethoxy-1,1,5-trimethyl-, cis-(9CI);
2-Pentanone, 4-mercapto-4-methyl-; 2,4,6-Octatriene, 2,6-dimethyl-,
(4E,6E)-; Oxirane, 2,2-dimethyl-3-(3-methyl-2,4-pentadien-1-yl)-;
4,7-Octadienoic acid, methyl ester, (4E)-; Carbonic acid,
(3Z)-3-hexen-1-yl methyl ester; Hexanoic acid, 2-propen-1-yl ester;
5-Heptenal, 2,6-dimethyl-; Heptanoic acid, ethyl ester;
3-Cyclohexene-1-carboxaldehyde, 2,4-dimethyl-; Benzene,
(2,2-dimethoxyethyl)-; 2H-Pyran,
tetrahydro-4-methyl-2-(2-methyl-1-propen-1-yl)-; 3-Nonanone;
Benzonitrile; 3-Octanol; 1-Hexanol, 3,5,5-trimethyl-, 1-acetate;
4-Heptanol, 2,6-dimethyl-, 4-acetate; Hexanoic acid, 2-methylpropyl
ester; Propanoic acid, 2-methyl-, hexyl ester;
Cyclohexanecarboxylic acid, 1,4-dimethyl-, methyl ester, trans-;
Benzeneacetaldehyde; Butanoic acid, 3-hydroxy-, ethyl ester;
Propanedioic acid, 1,3-diethyl ester; Benzoic acid, methyl ester;
1,3,5-Undecatriene; 4-Decenal, (4E)-; 1,3-Dioxane,
2-butyl-4,4,6-trimethyl-; 2-Heptanol, 2,6-dimethyl-; Ethanone,
1-phenyl-; Benzeneacetaldehyde, .alpha.-methyl-; Propanoic acid,
2-methyl-, 1,3-dimethyl-3-buten-1-yl ester; 2,6-Nonadienal,
(2E,6Z)--; Pyrazine, 2-methoxy-3-(2-methylpropyl)-; Formic acid,
phenylmethyl ester; Benzene, 1-methoxy-4-propyl-; Cyclohexanone,
5-methyl-2-(1-methylethyl)-, (2R,5R)-rel-; Cyclohexanone,
5-methyl-2-(1-methylethyl)-, (2R,5S)-rel-; 2-Nonenal;
Cyclohexanone, 2-ethyl-4,4-dimethyl-; Benzene, 1,4-dimethoxy-;
Benzene, 1-(ethoxymethyl)-2-methoxy-; Bicyclo[2.2.1]heptan-2-one,
1,7,7-trimethyl-; 2-Hexene, 6,6-dimethoxy-2,5,5-trimethyl-;
Decanal; Benzenepropanal, .beta.-methyl-; Benzenemethanol,
.alpha.-methyl-, 1-acetate; Acetic acid, nonyl ester; Ethanone,
1-(4-methylphenyl)-; 2H-Pyran, 6-butyl-3,6-dihydro-2,4-dimethyl-;
Propanoic acid, 2-methyl-, (3Z)-3-hexen-1-yl ester; Benzoic acid,
ethyl ester; 3-Octanol, 3,7-dimethyl-, 3-acetate; 1-Hexanol,
5-methyl-2-(1-methylethyl)-, 1-acetate; Cyclohexanol,
3,3,5-trimethyl-, (1R,5R)-rel-; 2-Hexenal,
5-methyl-2-(1-methylethyl)-; 7-Octen-2-ol, 2,6-dimethyl-; Acetic
acid, phenylmethyl ester; Cyclohexanone, 2-(1-methylpropyl)-;
3-Octen-1-ol, (3Z)--; Heptanoic acid, 2-propen-1-yl ester;
Benzenemethanol; Butanoic acid, 2-methyl-, hexyl ester;
2(3H)-Furanone, 5-ethyldihydro-; Cyclohexaneethanol, 1-acetate;
2-Nonenoic acid, methyl ester; Cyclohexanecarboxylic acid,
2,2-dimethyl-6-methylene-, methyl ester; Butanoic acid,
(3Z)-3-hexen-1-yl ester; 2-Octynoic acid, methyl ester;
1,3-Oxathiane, 2-methyl-4-propyl-, (2R,4S)-rel-; Heptanal,
6-methoxy-2,6-dimethyl-; Bicyclo[2.2.1]heptan-2-ol,
1,3,3-trimethyl-, 2-acetate; 1,6-Octadien-3-ol, 3,7-dimethyl-,
3-acetate; 2-Octanol, 2,6-dimethyl-; 1-Octanol;
3-Cyclohexene-1-methanethiol, .alpha.,.alpha.,4-trimethyl-;
Cyclohexanemethanol, .alpha.,.alpha.,4-trimethyl-, 1-acetate;
Cyclohexanol, 2-(1,1-dimethylethyl)-, 1-acetate; Cyclohexanol,
4-(1,1-dimethylethyl)-, 1-acetate; Pyrazine,
2-methoxy-3-(1-methylpropyl)-; Cyclohexanol,
5-methyl-2-(1-methylethenyl)-, (1R,2S,5R)--; 2-Undecanone;
Benzenepropanol, .alpha.,.alpha.-dimethyl-;
Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, 2-acetate,
(1R,2R,4R)-rel-; 1,6-Octadien-3-ol, 3,7-dimethyl-; Benzeneacetic
acid, ethyl ester; Benzeneethanol, .alpha.,.alpha.-dimethyl-;
Cyclopropanecarboxylic acid, (3Z)-3-hexen-1-yl ester;
3-Cyclohexene-1-methanol, 3,5-dimethyl-, 1-acetate; Undecanal;
Ethanone, 1-(3-cycloocten-1-yl)-; Cyclohexanone,
4-(1,1-dimethylethyl)-; 6-Nonen-1-ol, (6Z)--; Benzene,
(2-butoxyethyl)-; Cyclohexanecarboxylic acid, 2,2,6-trimethyl-,
ethyl ester, (1R,6S)-rel-; Benzeneethanol; 2,6-Octadienal,
3,7-dimethyl-, (2Z)--; 2,6-Octadienal, 3,7-dimethyl-; Cyclohexanol,
5-methyl-2-(1-methylethyl)-, 1-acetate, (1R,2S,5R)-rel-; Benzoic
acid, 2-hydroxy-, methyl ester; Benzene,
1-methoxy-4-(1E)-1-propen-1-yl-; 2,6-Octadiene,
1,1-dimethoxy-3,7-dimethyl-; Cyclohexanemethanol,
.alpha.,3,3-trimethyl-, 1-formate; 2-Decenal, (2E)-;
3-Cyclopentene-1-acetonitrile, 2,2,3-trimethyl-;
2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl)-, (5R)--;
Cyclohexanone, 4-(1,1-dimethylpropyl)-; 2-Cyclohexen-1-one,
3-methyl-5-propyl-; Benzonitrile, 4-(1-methylethyl)-;
2,6-Nonadienenitrile; Butanoic acid, 2-methyl-, (3Z)-3-hexen-1-yl
ester; Benzene, 1-(cyclopropylmethyl)-4-methoxy-; 2-Nonynoic acid,
methyl ester; Acetic acid, 2-phenylethyl ester; Cyclohexanol,
2-(1,1-dimethylethyl)-; 2,6-Nonadien-1-ol; Propanoic acid,
2-methyl-, phenylmethyl ester; Bicyclo[2.2.1]heptan-2-ol,
1,2,3,3-tetramethyl-, (1R,2R,4S)-rel-; Benzaldehyde,
4-(1-methylethyl)-; 2,5-Octadien-4-one, 5,6,7-trimethyl-, (2E)-;
3-Cyclohexen-1-ol, 4-methyl-1-(1-methylethyl)-;
3-Cyclohexene-1-methanol, 2,4,6-trimethyl-; Pentanoic acid,
(3Z)-3-hexen-1-yl ester; Bicyclo[2.2.1]heptan-2-ol,
1,7,7-trimethyl-, 2-propanoate, (1R,2R,4R)-rel-; Benzene,
1-methyl-4-(1-methylethyl)-2-(1-propen-1-yl)-; 2,4-Nonanedione,
3-methyl-; 3-Cyclohexene-1-propanal, .beta.,4-dimethyl-; 1-Hexanol,
5-methyl-2-(1-methylethyl)-, (2R)--; 3-Heptanone, 5-methyl-, oxime;
2(3H)-Furanone, 5-butyldihydro-; 1-Nonanol; Acetic acid,
2-(3-methylbutoxy)-, 2-propen-1-yl ester;
Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1S,2R,4S)--;
Bicyclo[2.2.1]heptan-2-ol, 1,7,7-trimethyl-, (1R,2R,4R)-rel-;
Cyclohexanol, 2-(1,1-dimethylpropyl)-, 1-acetate;
3-Cyclohexene-1-methanol, .alpha.,.alpha.,4-trimethyl-, 1-acetate;
Cyclohexanemethanol, .alpha.,.alpha.,4-trimethyl-; 10-Undecenal;
1-Octanol, 3,7-dimethyl-; Furan, tetrahydro-2,4-dimethyl-4-phenyl-;
Benzene, [2-(3-methylbutoxy)ethyl]-; Butanoic acid, phenylmethyl
ester; Benzoic acid, 2-hydroxy-, ethyl ester; Cyclohexanol,
4-(1,1-dimethylethyl)-; 1,6-Octadien-3-ol, 3,7-dimethyl-,
3-formate; Dodecanal; 3,6-Nonadien-1-ol, (3Z,6Z)--; Decanenitrile;
Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)--; Propanoic
acid, 2-methyl-, 4-methylphenyl ester; Propanoic acid, 2-methyl-,
(1R,2S,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl ester, rel-;
Acetaldehyde, 2-(4-methylphenoxy)-; 2-Butenoic acid, 2-methyl-,
(3Z)-3-hexen-1-yl ester, (2E)-;
Bicyclo[3.1.1]hept-2-ene-2-propanal, 6,6-dimethyl-; 2-Nonanol,
6,8-dimethyl-; Cyclohexanol, 1-methyl-3-(2-methylpropyl)-;
1H-Indole; 2-Undecenal; 2H-Pyran-2-one, 4,6-dimethyl-;
3-Cyclohexene-1-methanol, .alpha.,.alpha.,4-trimethyl-;
3-Hepten-2-one, 3,4,5,6,6-pentamethyl-, (3Z)--; 2(3H)-Furanone,
5-butyldihydro-4-methyl-; 7-Octen-2-ol, 2,6-dimethyl-, 2-acetate;
2-Propenal, 3-phenyl-; 1,6-Octadien-3-ol, 3,7-dimethyl-,
3-propanoate; 1,6-Nonadien-3-ol, 3,7-dimethyl-, 3-acetate;
Cyclopentanone, 2,2,5-trimethyl-5-pentyl-; 2,6-Octadien-1-ol,
3,7-dimethyl-, 1-acetate, (2Z)--; 2,6-Octadien-1-ol, 3,7-dimethyl-,
1-acetate, (2E)-; Undecane, 1,1-dimethoxy-2-methyl-;
Benzenemethanol, .alpha.-methylene-, 1-acetate; Benzaldehyde,
4-methoxy-; Cyclohexanol, 5-methyl-2-(1-methylethenyl)-, 1-acetate,
(1R,2S,5R)--; 6-Octenenitrile, 3,7-dimethyl-; 6-Octen-2-ol,
2,6-dimethyl-; Benzene, 1,1'-oxybis-; Benzoic acid, butyl ester;
5,8-Methano-2H-1-benzopyran, 6-ethylideneoctahydro-;
Cyclohexanepropanol, .alpha.,.alpha.-dimethyl-; Benzenepropanal,
.beta.-methyl-3-(1-methylethyl)-; Benzenemethanol, 4-methoxy-,
1-acetate; Phenol, 2-ethoxy-4-methyl-; Benzene,
[2-(1-propoxyethoxy)ethyl]-; 7-Octen-1-ol, 3,7-dimethyl-;
Bicyclo[4.3.1]decane, 3-methoxy-7,7-dimethyl-10-methylene-;
Propanoic acid, 2-(1,1-dimethylpropoxy)-, propyl ester, (2S)--;
Benzoic acid, 2-(methylamino)-, methyl ester; 6-Octen-1-ol,
3,7-dimethyl-, (3S)--; 7-Octen-2-ol, 2-methyl-6-methylene-;
4,6-Octadien-3-ol, 3,7-dimethyl-;
5-Oxatricyclo[8.2.0.04,6]dodecane, 4,9,12,12-tetramethyl-;
2-Cyclohexene-1-carboxylic acid, 2-ethyl-6,6-dimethyl-, ethyl
ester; 3-Buten-2-one, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,
(3E)-; 4,7-Methano-1H-inden-5-ol, octahydro-, 5-acetate; Benzoic
acid, 2-amino-, methyl ester;
Spiro[1,3-dioxolane-2,8'(5'H)-[2H-2,4a]methanonaphthalene],
hexahydro-1',1',5',5'-tetramethyl-, (2'S,4'aS,8'aS)-(9CI);
3-Buten-2-one, 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, (3E)-;
Benzeneethanol, .alpha.,.alpha.-dimethyl-, 1-acetate;
4,7-Methano-1H-inden-5-ol, 3a,4,5,6,7,7a-hexahydro-, 5-acetate;
6-Octen-1-ol, 3,7-dimethyl-, 1-acetate; 2H-Pyran,
tetrahydro-2-methyl-4-methylene-6-phenyl-; Bicyclo[3.3.1]nonane,
2-ethoxy-2,6,6-trimethyl-9-methylene-; 2,6-Octadien-1-ol,
3,7-dimethyl-, (2E)-; Bicyclo[7.2.0]undec-4-ene,
4,11,11-trimethyl-8-methylene-, (1R,4E,9S)--;
1H-3a,7-Methanoazulene, octahydro-6-methoxy-3,6,8,8-tetramethyl-,
(3R,3aS,6S,7R,8aS)-; Bicyclo[7.2.0]undec-4-ene,
4,11,11-trimethyl-8-methylene-, (1R,4E,9S)--; 1H-Inden-1-one,
2,3-dihydro-2,3,3-trimethyl-; 2-Propanol, 1,1'-oxybis-; 2-Octanol,
7-methoxy-3,7-dimethyl-; 4,9-Decadienal, 4,8-dimethyl-; 3-Hexenoic
acid, (3Z)-3-hexen-1-yl ester, (3Z)--;
Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 3-(1-methylethyl)-,
ethyl ester, (1R,2S,3S,4S)-rel-; 2-Propen-1-ol, 3-phenyl-;
Propanoic acid, 2-methyl-, 1-ethenyl-1,5-dimethyl-4-hexen-1-yl
ester; Ethanol, 2-phenoxy-, 1-propanoate; 2-Propenoic acid,
3-phenyl-, methyl ester; Benzenepropanal,
2-ethyl-.alpha.,.alpha.-dimethyl-; Propanoic acid, decyl ester;
Benzene, 1,2-dimethoxy-4-(1-propen-1-yl)-; 3-Decen-5-ol, 4-methyl-;
Phenol, 2-methoxy-4-(2-propen-1-yl)-; 1-Propanone,
1-[2-methyl-5-(1-methylethyl)-2-cyclohexen-1-yl]-;
1,3-Benzodioxole-5-carboxaldehyde; 2-Dodecenal; 2-Dodecenal, (2E)-;
Benzenepropanal, 4-methoxy-.alpha.-methyl-;
1,4-Cyclohexanedicarboxylic acid, 1,4-dimethyl ester;
2-Buten-1-one, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)-; 2-Butanone,
4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-; 2-Propenenitrile,
3-phenyl-, (2E)-; Propanoic acid, 2-methyl-, 2-phenylethyl ester;
2-Cyclopenten-1-one, 3-methyl-2-(2Z)-2-penten-1-yl-; Acetaldehyde,
2-[(3,7-dimethyl-6-octen-1-yl)oxy]-; 1-Cyclohexene-1-ethanol,
4-(1-methylethyl)-, 1-formate; 2,4-Decadienoic acid, ethyl ester,
(2E,4Z)--; 2-Propen-1-ol, 3-phenyl-, 1-acetate;
Naphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-,
(3aR,5aS,9aS,9bR)-; Benzenepropanal, 4-(1,1-dimethylethyl)-;
1,4-Methanonaphthalen-5 (1H)-one, 4,4a,6,7,8,8a-hexahydro-;
Dodecanoic acid, 12-hydroxy-, .lamda.-lactone (6CI,7CI); 1,12-;
Cyclohexanepropanoic acid, 2-propen-1-yl ester; 2(3H)-Furanone,
5-hexyldihydro-5-methyl-; 2,6-Nonadienenitrile, 3,7-dimethyl-;
10-Undecenoic acid, ethyl ester; Benzenepropanal,
.alpha.-methyl-4-(1-methylethyl)-; 1-Oxaspiro[4.5]decan-2-one,
8-methyl-; 2(3H)-Furanone, dihydro-5-pentyl-; 2(3H)-Furanone,
5-hexyldihydro-; 2-Buten-1-one,
1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, (2E)-; 2-Buten-1-one,
1-(2,4,4-trimethyl-2-cyclohexen-1-yl)-, (2E)-; 2H-Pyran-2-one,
tetrahydro-6-pentyl-; Benzenepropanal,
4-ethyl-.alpha.,.alpha.-dimethyl-; 1,3-Benzodioxole,
5-(diethoxymethyl)-; 4-Penten-1-one,
1-(5,5-dimethyl-1-cyclohexen-1-yl)-;
Bicyclo[3.1.1]hept-2-ene-2-ethanol, 6,6-dimethyl-, 2-acetate;
2-Propenoic acid, 3-phenyl-, ethyl ester; 1,3-Dioxane,
2,4,6-trimethyl-4-phenyl-; Cyclododecane, (methoxymethoxy)-;
Bicyclo[3.1.1]hept-2-ene-2-propanal,
.alpha.,.alpha.,6,6-tetramethyl-; 2(3H)-Benzofuranone,
hexahydro-3,6-dimethyl-; Benzeneacetonitrile,
4-(1,1-dimethylethyl)-; 2-Buten-1-one,
1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-;
1,4-Methanonaphthalen-6(2H)-one, octahydro-7-methyl-;
Bicyclo[3.2.1]octan-8-one, 1,5-dimethyl-, oxime; Benzenepentanol,
.gamma.-methyl-; Cyclohexene,
4-(1,5-dimethyl-4-hexen-1-ylidene)-1-methyl-; Phenol,
2-methoxy-4-propyl-; Benzoic acid, 2-hydroxy-, 2-methylpropyl
ester; 2H-1-Benzopyran-2-one, octahydro-; Cyclohexanone,
2-(1-mercapto-1-methylethyl)-5-methyl-; 2-Oxiranecarboxylic acid,
3-methyl-3-phenyl-, ethyl ester; 3-Cyclohexene-1-carboxaldehyde,
4-(4-methyl-3-penten-1-yl)-; Propanoic acid, 2-methyl-,
2-phenoxyethyl ester; Indeno[1,2-d]-1,3-dioxin,
4,4a,5,9b-tetrahydro-; 2H-Pyran-4-ol,
tetrahydro-4-methyl-2-(2-methylpropyl)-; Cyclohexanebutanal,
a,2,6,6-tetramethyl-; 1,6-Nonadien-3-ol, 3,7-dimethyl-;
3-Buten-2-one, 4-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-;
Phenol, 2-methoxy-4-(1-propen-1-yl)-; 2(3H)-Furanone,
5-hexyldihydro-4-methyl-; 1-Penten-3-one,
1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-; 2-Buten-1-one,
1-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-; 2-Cyclopenten-1-one,
2-hydroxy-3-methyl-; Propanoic acid, 2,2-dimethyl-, 2-phenylethyl
ester; Dodecanenitrile; 6-Octen-1-ol, 3,7-dimethyl-, 1-propanoate;
Benzenepentanal, .beta.-methyl-; Acetic acid, 2-phenoxy-,
2-propen-1-yl ester; Benzenepropanal,
4-(1,1-dimethylethyl)-.alpha.-methyl-;
4,7-Methano-1H-indene-2-carboxaldehyde, octahydro-5-methoxy-;
Pentitol, 1,5-anhydro-2,4-dideoxy-2-pentyl-, 3-acetate;
Cyclododecane, (ethoxymethoxy)-; 3-Buten-2-one,
4-(2,5,6,6-tetramethyl-2-cyclohexen-1-yl)-; Indeno[4,3a-b]furan,
decahydro-2,2,7,7,8,9,9-heptamethyl-; Quinoline,
6-(1-methylpropyl)-; Carbonic acid, 4-cycloocten-1-yl methyl ester;
1H-Indene-5-propanal, 2,3-dihydro-3,3-dimethyl-;
3-Cyclohexene-1-carboxaldehyde,
1-methyl-3-(4-methyl-3-penten-1-yl)-; 6-Oxabicyclo[3.2.1]octane,
5-methyl-1-(2,2,3-trimethyl-3-cyclopenten-1-yl)-; 2H-Pyran-2-one,
tetrahydro-6-(3-penten-1-yl)-; 2,4,7-Decatrienoic acid, ethyl
ester; Butanoic acid, 3-methyl-, 2-phenylethyl ester;
Spiro[1,4-methanonaphthalene-2(1H), 2'-oxirane],
3,4,4a,5,8,8a-hexahydro-3',7-dimethyl-; Ethanol,
2-[[(1R,2R,4R)-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl]oxy]-, rel-;
Phenol, 2-methoxy-4-(1-propen-1-yl)-, 1-acetate;
2H-Indeno[4,5-b]furan, decahydro-2,2,6,6,7,8,8-heptamethyl-; Acetic
acid, 2-(cyclohexyloxy)-, 2-propen-1-yl ester; Octanal,
7-hydroxy-3,7-dimethyl-; 1,6-Heptadien-3-one, 2-cyclohexyl-;
5-Thiazoleethanol, 4-methyl-; 1,4-Cyclohexanedicarboxylic acid,
1,4-diethyl ester; 2(3H)-Furanone, 5-heptyldihydro-;
1,3-Benzodioxole-5-propanal, .alpha.-methyl-; 4H-Inden-4-one,
1,2,3,5,6,7-hexahydro-1,1,2,3,3-pentamethyl-; Cyclohexanone,
4-(1-ethoxyethenyl)-3,3,5,5-tetramethyl-; Benzenepropanenitrile,
.alpha.-ethenyl-.alpha.-methyl-; 9-Undecenal, 2,6,10-trimethyl-;
Pyridine, 2-(3-phenylpropyl)-; Indeno[1,2-d]-1,3-dioxin,
4,4a,5,9b-tetrahydro-2,4-dimethyl-; Propanoic
acid, 2-methyl-, 3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-5-yl
ester; 1-Naphthalenol,
1,2,3,4,4a,7,8,8a-octahydro-2,4a,5,8a-tetramethyl-, 1-formate;
Benzenepropanol, .beta.,.beta.,3-trimethyl-; 2-Cyclohexen-1-one,
4-(2-buten-1-ylidene)-3,5,5-trimethyl-; 3-Hexen-1-ol, 1-benzoate,
(3Z)--; Benzaldehyde, 4-hydroxy-3-methoxy-;
1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-,
6-acetate, (3R,3aS,6R, 7R,8aS)-; 4,7-Methano-1H-inden-6-ol,
3a,4,5,6,7,7a-hexahydro-8,8-dimethyl-, 6-propanoate;
2-Oxiranecarboxylic acid, 3-phenyl-, ethyl ester;
4H-4a,9-Methanoazuleno[5,6-d]-1,3-dioxole,
octahydro-2,2,5,8,8,9a-hexamethyl-, (4aR,5R,7aS,9R)--;
1H-Indene-2-methanol, 2,3-dihydro-2,5-dimethyl-; Butanoic acid,
1,1-dimethyl-2-phenylethyl ester; Cyclododeca[c]furan,
1,3,3a,4,5,6,7,8,9,10,11,13a-dodecahydro-; Benzenebutanenitrile,
.alpha.,.alpha.,.gamma.-trimethyl-; 2-Butanone,
4-(1,3-benzodioxol-5-yl)-; Benzoic acid, 4-hydroxy-3-methoxy-,
methyl ester; 3-Cyclopentene-1-butanol,
.beta.,2,2,3-tetramethyl-2-Methyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)b-
utanol; 2-Butenal, 2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-;
2-Naphthalenol, decahydro-2,5,5-trimethyl-; 1,7-Octanediol,
3,7-dimethyl-; 2H-1-Benzopyran-2-one; 1,3-Dioxolane,
2-[6-methyl-8-(1-methylethyl)bicyclo[2.2.2]oct-5-en-2-yl]-;
Propanoic acid, 2,2-dimethyl-,
3a,4,5,6,7,7a-hexahydro-4,7-methano-1H-inden-6-yl ester; Butanoic
acid, (2E)-3,7-dimethyl-2,6-octadien-1-yl ester; 2-Butanone,
4-(4-hydroxyphenyl)-; 10-Undecenoic acid, butyl ester; and
combinations thereof.
[0095] In one aspect, said perfume composition comprises ethanol in
the amount of from about 50 wt % to about 80 wt %, or from about 55
wt % to about 75 wt %, relative to the total weight of the
composition.
[0096] In one aspect, said perfume composition comprises one or
more non-odorous fragrance co-modulators selected from the group
consisting of: [0097] a) Isocetyl alcohol, for example CERAPHYL
ICA; [0098] b) PPG-3 myristyl ether for example, Tegosoft APM
and/or Varonic APM; [0099] c) Neopentyl glycol diethylhexanoate for
example Schercemol NGDO; and [0100] d) mixtures thereof. wherein
the one or more non-odorous fragrance co-modulators are present in
the amount of from about 0.05 wt % to about 10 wt %, preferably
from about 0.5 wt % to about 6 wt %, relative to the total weight
of the composition.
[0101] In one aspect, said perfume composition comprises isocetyl
alcohol.
[0102] In one aspect, said perfume composition the non-odorous
fragrance modulators are formed of at least 50 wt % of PPG-20
Methyl Glucose Ether, relative to the combined weight of the
non-odorous fragrance modulators and the non-odorous fragrance
co-modulators.
[0103] In one aspect, said perfume composition, said composition
comprises: [0104] at least one low volatile fragrance material
having a vapor pressure <0.001 Torr, in the amount of from about
0.1 wt % to about 30 wt %, relative to the total weight of the
fragrance component; [0105] (i) at least one volatile fragrance
material having a vapor pressure >0.001 Torr in the amount of
from about 70 wt % to about 99.9 wt %, relative to the total weight
of the fragrance component; and [0106] (ii) a non-odorous fragrance
modulator formed of an alkoxylated methyl glucoside, preferably
PPG-20 Methyl Glucose Ether, in the amount of from about 0.1 wt %
to about 20 wt %, relative to the total weight of the
composition.
[0107] In one aspect, of said perfume composition said composition
comprises one or more non-odorous fragrance co-modulators selected
from the group consisting of Isocetyl alcohol, for example,
CERAPHYL ICA; PPG-3 myristyl ether for example, Tegosoft APM and/or
Varonic APM; Neopentyl glycol diethylhexanoate, for example,
Schercemol NGDO; or mixtures thereof, in one aspect in the amount
of from about 0.5 wt % to about 6 wt %, relative to the total
weight of the composition.
[0108] In one aspect, said perfume composition is in the form of a
perfume, an eau de toilette, an eau de parfum, a cologne, a body
splash, or a body spray.
[0109] In one aspect, a perfume raw material having a two week
anti-habituation index of at least 0, 1, 2, 3, or 4; a four week
anti-habituation index of at least 0, 1, 2, 3 or 4; a two week
anti-habituation index of 0, 1, 2, 3, or 4; and/or a four week
anti-habituation index of 0, 1, 2, 3, or 4, with the proviso that
said perfume raw material is not: [0110] a) said perfume raw
material comprising a thiol moiety is selected from the group
consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; methanethiol; Ethanethiol;
prop-2-ene-1-thiol; propane-2-thiol; 2-methylpropane-2-thiol;
propane-1-thiol; butane-2-thiol; butane-1-thiol;
2-methylpropane-1-thiol; methyldisulfanylmethane;
2-methylbutane-2-thiol; 3-methylbutane-2-thiol;
3-methylbutane-2-thiol; pentane-2-thiol; pentane-1-thiol;
2-methylbutane-1-thiol; cyclopentanethiol;
3-methyldisulfanylprop-1-ene; methylsulfanyldisulfanylmethane;
1-methyldisulfanylpropane; ethane-1,2-dithiol;
1-(methyldisulfanyl)prop-1-ene; 3-sulfanylbutan-2-one;
ethyldisulfanylethane; hexane-1-thiol; 1-ethyldisulfanylpropane;
thiophene-2-thiol; propane-1,3-dithiol; 3-sulfanylpentan-2-one;
2-propan-2-yldisulfanylpropane; butane-1,4-dithiol; benzenethiol;
ethylsulfanyldisulfanylethane;
3-methylsulfanyldisulfanylprop-1-ene;
1-methylsulfanyldisulfanylpropane; butane-2,3-dithiol;
4-methyl-4-sulfanylpentan-2-one; 3-prop-2-enyldisulfanylprop-1-ene;
1-methoxyhexane-3-thiol; ethyl 2-sulfanylpropanoate;
1-(prop-2-enyldisulfanyl)propane; 1-propyldisulfanylpropane;
1-(4-hydroxy-3-methoxyphenyl)ethanone butane-1,3-dithiol;
1-propyldisulfanylprop-1-ene; 2-methylbenzenethiol;
thiophen-2-ylmethanethiol; 3-sulfanylbutan-2-ol;
phenylmethanethiolpentane-1,5-dithiol; 2-ethylbenzenethiol;
3-prop-2-enylsulfanyldisulfanylprop-1-ene;
methyldisulfanyldisulfanylmethane;
1-propylsulfanyldisulfanylpropane;
2,7,7-trimethylbicyclo[3.1.1]heptane-2-thiol;
2,6-dimethylbenzenethiol; 2-phenylethanethiol; hexane-1,6-dithiol;
2-(methyldisulfanylmethyl)furan; pyridin-2-ylmethanethiol;
2-methoxybenzenethiol;
(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)methanethiol;
methyldisulfanylbenzene; 1-butyldisulfanylbutane;
(4-methoxyphenyl)methanethiol; 2-sulfanylpropanoic acid; ethyl
2-methyldisulfanylpropanoate;
(2E)-3,7-dimethylocta-2,6-diene-1-thiol;
3,7-dimethylocta-2,6-diene-1-thiol; pyrazin-2-ylmethanethiol;
methyldisulfanylmethylbenzene;
2-methyl-5-(1-sulfanylpropan-2-yl)cyclohexane-1-thiol;
octane-1,8-dithiol; 2-pyrazin-2-ylethanethiol; naphthalene-2-thiol;
2-oxo-3-sulfanylpropanoic acid; 2-thiophen-2-yldisulfanylthiophene;
cyclohexyldisulfanylcyclohexane;
2-(furan-2-ylmethyldisulfanylmethyl)furan; phenyldisulfanylbenzene;
benzyldisulfanylmethylbenzene; 8-Hydroxy-5-quinolinesulfonic acid;
bis(3-methylbutyl) 2-sulfanylbutanedioate; 2-aminoethanesulfonic
acid; 2-phenyl-3H-benzimidazole-5-sulfonic acid;
2-methyl-2-sulfanylpentan-1-ol; and mixtures thereof; [0111] b)
said perfume raw material comprising a sulfide moiety is selected
from the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan;
methylsulfanylmethane; methylsulfanylethane;
3-methylsulfanylprop-1-ene; S-methyl ethanethioate;
ethylsulfanylethane; 1-methylsulfanylpropane; S-ethyl
ethanethioate; 1-methylsulfanylbutane;
2-propan-2-ylsulfanylpropane; bis(methylsulfanyl)methane;
1-ethylsulfanylpropane; thiolane; 1-propylsulfanylpropane;
1-ethylsulfanylbutane; S-ethyl propanethioate; S-methyl
butanethioate; S-methyl 3-methylbutanethioate;
3-methylsulfanylpropanal; 3-prop-2-enylsulfanylprop-1-ene; methyl
2-methylsulfanylacetate; S-prop-2-enyl propanethioate;
1-methylsulfanylbutan-2-one; 4-methylsulfanylbutan-2-one;
3-methylsulfanylpropan-1-am; 2,4,6-trimethyl-1,3,5-trithiane;
3-methylsulfanylbutanal; 2-methyl-1,3-thiazolidine;
2-methyl-4,5-dihydro-1,3-thiazole; ethyl 2-methylsulfanylacetate;
methyl 3-methylsulfanylpropanoate; S-propan-2-yl
3-methylbutanethioate; 4-methyl-4-methylsulfanylpentan-2-one;
2-methyl-1,3-dithiolane; methyl 2-methylsulfanylbutanoate; S-methyl
furan-2-carbothioate; S-propan-2-yl 3-methylbut-2-enethioate;
thiolan-3-one; 3,5-diethyl-1,2,4-trithiolane;
methylsulfanylmethylbenzene; 3-methylsulfanylpropan-1-ol;
2-(propan-2-ylsulfanylmethyl)furan; 2-methyl-5-methylsulfanylfuran;
S-(furan-2-ylmethyl) methanethioate; 1,2,4-trithiolane;
2-methylthiolan-3-one; 4-methylsulfanylbutan-1-ol; S-butan-2-yl
3-methylbutanethioate; S-butan-2-yl 3-methylbut-2-enethioate;
S-(furan-2-ylmethyl)ethanethioate; 2-propyl-1,3-thiazolidine;
3-methyl-1,1-bis(methylsulfanyl)butane; 3-ethylsulfanylpropan-1-ol;
S-methyl benzenecarbothioate; 3,5-dimethyl-1,2,4-trithiolane;
S-butan-2-yl 2-methylbutanethioate; methylsulfanylbenzene;
1-pentylsulfanylpentane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-methyl-4-propyl-1,3-oxathiane; ethyl
2-methyl-2-methylsulfanylpropanoate; S-(furan-2-ylmethyl)
propanethioate; 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
3-methyl-1,2,4-trithiane; methylsulfanylmethyl hexanoate;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone; 3-methylsulfanylpropanoic
acid; 5-methylsulfanyl-2-(methylsulfanylmethyl)pent-2-enal;
4,5-dimethyl-2-(2-methylpropyl)-2,5-dihydro-1,3-thiazole;
3-methylsulfanylhexan-1-ol; 2-methyl-4,5-dihydrofuran-3-thiol
acetate; 4-(3-oxobutylsulfanyl)butan-2-one;
3-methylsulfanylbutanoic acid; 2-methylsulfanylpyrazine;
2-methyl-3-methylsulfanylpyrazine;
2-(furan-2-ylmethylsulfanylmethyl)furan;
2-(methylsulfanylmethyl)pyrazine;
3,5-di(propan-2-yl)-1,2,4-trithiolane; 2-methylsulfanylphenol;
2-methyl-3-methylsulfanylpyrazine; ethyl
3-(furan-2-ylmethylsulfanyl)propanoate;
2,2,4,4,6,6-hexamethyl-1,3,5-trithiane;
2-methyl-5,7-dihydrothieno[3,4-d]pyrimidine;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolan-
e]; 2,5-dimethyl-1,4-dithiane-2,5-diol; Methyl 2-thiofuroate and
mixtures thereof; [0112] c) said perfume raw material comprising a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
2,4,5-Trimethylthiazole; 2-isopropyl-4-methylthiazole;
4-vinyl-5-methylthiazole; 2,4-Dimethyl-5-acetylthiazole
1,3-thiazole; 4-methyl-1,3-thiazole; 2,4-dimethyl-1,3-thiazole;
4,5-dimethyl-1,3-thiazole; 2,5-dimethyl-1,3-thiazole;
5-ethenyl-4-methyl-1,3-thiazole; 2-ethyl-4-methyl-1,3-thiazole;
4-ethyl-2-methyl-1,3-thiazole; 2-propyl-1,3-thiazole;
2,4,5-trimethyl-1,3-thiazole; 2-ethyl-1,3-thiazole;
2-ethoxy-1,3-thiazole; 2-butan-2-yl-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole; 2-ethyl-4,5-dimethyl-1,3-thiazole;
1,3-benzothiazole; 2,5-diethyl-4-methyl-1,3-thiazole;
1-(1,3-thiazol-2-yl)propan-1-one;
4,5-dimethyl-2-(2-methylpropyl)-1,3-thiazole;
2-methyl-1,3-benzothiazole;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
4-methyl-2-propan-2-yl-1,3-thiazole; and mixtures thereof; [0113]
d) said perfume raw material comprising a pyrazine moiety is
selected from the group consisting of
2-methoxy-3-(2-methylpropyl)pyrazine; 2,3-dimethylpyrazine;
1-pyrazin-2-ylethanone; 2-methyl-3-methylsulfanylpyrazine;
Pyrazine; 2-methylpyrazine; 2-ethenylpyrazine; 2-ethylpyrazine;
2,6-dimethylpyrazine; 2,5-dimethylpyrazine;
2-prop-1-en-2-ylpyrazine; 2-propan-2-ylpyrazine; 2-methoxypyrazine;
2-ethenyl-5-methylpyrazine; 2-ethyl-5-methylpyrazine;
2-Ethyl-6-methylpyrazine; 2-Ethyl-3-Methyl-Pyrazine;
2-propylpyrazine; 2,3,5-trimethylpyrazine; 2-tert-butylpyrazine;
pyrazin-2-amine; 2-(2-methylpropyl)pyrazine;
2-methyl-5-propan-2-ylpyrazine; 2-(methoxymethyl)pyrazine;
2,3-diethylpyrazine; 2-ethyl-3,(5 OR 6)-dimethylpyrazine;
2-ethyl-3,5-dimethylpyrazine; 3-ethyl-2,5-dimethylpyrazine;
3-ethyl-2,5-dimethylpyrazine; 2-ethyl-3,5-dimethylpyrazine;
2-methyl-3-propylpyrazine; 2,3,5,6-tetramethylpyrazine;
7-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine;
2-methylsulfanylpyrazine; 2-methyl-3-methylsulfanylpyrazine;
2-ethoxy-3-ethylpyrazine; 2-Isobutyl-3-methylpyrazine;
pyrazin-2-ylmethanethiol; 3,5-dimethyl-2-propylpyrazine;
2-ethyl-3-methoxypyrazine; 2-ethoxy-3-methylpyrazine;
2-ethyl-5-methoxypyrazine; 5,6,7,8-tetrahydroquinoxaline;
2-ethoxy-3-propan-2-ylpyrazine; 2-(methylsulfanylmethyl)pyrazine;
3,5-dimethyl-2-(2-methylpropyl)pyrazine;
2,3-diethyl-5-methylpyrazine; 3,5-Diethyl-2-methylpyrazine;
2,5-dimethyl-3-(2-methylpropyl)pyrazine;
2-methyl-6-propoxypyrazine; 2-(2-methylpropoxy)pyrazine;
1-(3-methylpyrazin-2-yl)ethanone;
2-methyl-3-methylsulfanylpyrazine; 2-methoxy-3-propan-2-ylpyrazine;
quinoxaline; 3-butyl-2,5-dimethylpyrazine;
2-butyl-3,5-dimethylpyrazine; 2-pyrazin-2-ylethanethiol;
1-(3-ethylpyrazin-2-yl)ethanone;
1-(3,5-dimethylpyrazin-2-yl)ethanone;
2-butan-2-yl-3-methoxypyrazine; 2-methylquinoxaline;
5-Methylquinoxaline; 2-methoxy-3-(4-methylpentyl)pyrazine;
2,3-dimethylquinoxaline; 2-(cyclohexylmethyl)pyrazine;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine and mixtures
thereof; [0114] e) said perfume raw material comprising a nitrile
moiety is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
[0115] f) said perfume raw material comprising a indole moiety is
selected from the group consisting of 1H-indole,
3-methyl-1H-indole; and mixtures thereof; [0116] g) said perfume
raw material comprising a oxathiane moiety is selected from the
group consisting of (2R,4S)-2-methyl-4-propyl-1,3-oxathiane,
2-methyl-4-propyl-1,3-oxathiane, 2-pentyl-4-propyl-1,3-oxathiane;
and mixtures thereof; [0117] h) said perfume raw material
comprising a oxime moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
N-(5-methylheptan-3-ylidene)hydroxylamine, and mixtures thereof;
[0118] i) said perfume raw material comprising a amine moiety is
selected from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine; 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof
[0119] is disclosed.
[0120] In one aspect, any of said perfume raw materials disclosed
herein may be present in a perfume or a composition comprising said
perfume at a level below their respective odor detection
thresholds. In short, perfumes and compositions comprising same may
comprise one or more, for example 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10
etc., of the anti-habituating perfume raw materials at levels below
the respective odor detection thresholds of such anti-habituating
perfume raw materials.
Suitable perfumes include perfumes A through G in Table 1
below:
TABLE-US-00001 Perfume Raw Material Perfume A Perfume B Perfume C
Perfume D Perfume E Perfume F Perfume G 4-Tertiary Butyl 2.50%
2.50% 3.00% 3.00% 3.50% 3.50% 3.50% Cyclohexyl Acetate Allyl
Caproate 0.20% 0.10% 0.10% 0.20% 0.10% 0.20% 0.20% Allyl
Cyclohexane 1.25% 2.00% 1.25% 2.00% 2.00% 2.00% 2.00% Propionate
Allyl Heptoate 3.50% 2.90% 3.50% 3.50% 4.00% 3.00% 3.00% Benzyl
Acetate 3.00% 3.00% 3.00% 2.00% 2.00% 2.00% 3.00% Benzyl Salicylate
5.00% 5.00% 5.00% 5.00% 5.00% 5.00% 5.00% Beta Gamma Hexenol 0.20%
0.15% 0.10% 0.20% 0.15% 0.10% 0.20% Castech 1.00% 0.90% 1.00% 0.95%
1.25% 0.90% 0.85% Cis 3 Hexenyl Acetate 0.10% 0.20% 0.10% 0.10%
0.20% 0.10% 0.10% Cis Jasmone 0.10% 0.10% 0.10% 0.20% 0.10% 0.10%
0.10% Cyclopentol Hc 937165 0.20% 0.20% 0.40% 0.40% 0.20% 0.40%
0.40% Delta Damascone 0.10% 0.20% 0.10% 0.20% 0.10% 0.10% 0.10%
Dihydro Iso Jasmonate 1.00% 1.00% 1.25% 0.75% 1.50% 1.50% 0.79%
Dihydro Myrcenol 2.50% 3.00% 2.50% 2.50% 3.00% 3.00% 2.00% Dimethyl
Benzyl 4.00% 2.00% 5.00% 1.00% 3.50% 3.00% 2.00% Carbinyl Acetate
Dimethyl Benzyl 1.00% 2.00% 1.00% 1.00% 0.70% 1.00% 2.00% Carbinyl
Butyrate Ethyl 2 Methyl 0.20% 0.10% 0.15% 0.10% 0.15% 0.20% 0.40%
Pentanoate Ethyl Acetoacetate 1.50% 2.50% 2.50% 1.40% 1.75% 1.50%
2.00% Ethyl Butyrate 0.10% 0.10% 0.25% 0.25% 0.20% 0.20% 0.10%
Ethyl Caproate FCC 0.50% 0.40% 0.40% 0.50% 0.50% 0.50% 0.50% Ethyl
Maltol 0.75% 0.50% 0.75% 0.50% 0.50% 1.00% 1.00% Ethyl Oenanthate
0.50% 0.20% 0.15% 0.15% 0.20% 0.50% 0.40% Ethyl-2-Methyl 0.50%
0.75% 0.50% 0.50% 0.75% 0.75% 0.75% Butyrate Ethylene Brassylate
3.00% 4.00% 4.00% 5.00% 3.00% 3.00% 3.00% Florhydral 0.25% 0.25%
0.25% 0.50% 0.50% 0.50% 0.25% Gamma Decalactone 0.50% 1.00% 1.25%
0.78% 0.50% 0.40% 0.65% Grapefruit Zest #925 0.15% 0.30% 0.20%
0.25% 0.35% 0.35% 0.50% (C-Citrus&Allied) Hexamethylindanopyran
10.00% 8.00% 8.00% 8.00% 8.00% 10.00% 10.00% Hexyl Acetate 1.25%
1.75% 1.75% 1.50% 1.00% 0.50% 0.50% Hexyl Cinnamic 7.00% 8.50%
10.00% 10.00% 5.00% 5.00% 7.00% Aldehyde Indolene 0.10% 0.10% 0.10%
0.20% 0.10% 0.10% 0.20% Ionone Beta 2.00% 1.50% 1.25% 1.25% 1.50%
1.50% 1.00% Iso E Super Or Wood 2.50% 2.00% 1.50% 2.00% 2.00% 3.00%
2.50% Italian Mandarin Oil 0.50% 1.00% 0.50% 1.00% 0.50% 1.08%
0.50% Yellow #10567 Jasmal 0.50% 0.40% 0.40% 0.50% 0.40% 0.50%
0.40% Labienoxime 10 Opt 0.85% 0.75% 0.70% 1.00% 0.80% 1.00% 0.75%
Ligustral Or Triplal 0.20% 0.20% 0.40% 0.25% 0.35% 0.35% 0.20%
Linalool 6.00% 6.00% 6.00% 6.00% 6.00% 6.50% 7.00% Linalyl Acetate
2.00% 2.00% 1.00% 2.00% 2.00% 3.00% 1.00% Linalyl Benzoate 0.50%
1.00% 0.40% 0.40% 1.00% 0.50% 0.50% Methyl Dihydro 5.00% 5.00%
5.00% 5.00% 5.00% 5.00% 5.00% Jasmonate Methyl Iso Butenyl 0.05%
0.02% 0.02% 0.02% 0.05% 0.02% 0.01% Tetrahydro Pyran Methyl Phenyl
0.68% 0.75% 1.50% 1.50% 1.00% 1.00% 0.60% Carbinyl Acetate Nectaryl
2.00% 1.00% 1.00% 1.00% 2.00% 2.00% 1.00% Nonalactone 0.50% 0.50%
0.75% 0.25% 0.75% 0.20% 0.20% Oil Lemon Brazilcp 2.00% 3.00% 2.50%
2.00% 3.00% 2.50% 2.50% Select Fcc Enh 15130 Oil Pink Grapefruit
6.50% 7.00% 5.50% 7.00% 5.50% 6.50% 6.00% California Fcc 15029
Phenoxy Ethyl Iso 3.00% 3.00% 2.00% 3.00% 5.00% 2.00% 5.00%
Butyrate Prenyl Acetate 0.20% 0.25% 0.40% 0.25% 0.35% 0.45% 0.40%
Sandalore 0.50% 0.50% 0.50% 0.75% 1.00% 1.00% 1.00% Synambran R 50%
In 0.22% 0.18% 0.18% 0.20% 0.40% 0.50% 0.20% IPM Undecalactone
7.00% 4.50% 4.50% 5.00% 5.00% 4.50% 5.00% Undecavertol 0.10% 0.50%
0.10% 0.50% 0.10% 1.00% 0.50% Veloutone 0.25% 0.25% 0.25% 0.50%
0.50% 0.50% 0.25% Verdox 5.00% 5.00% 6.00% 6.00% 6.00% 5.00% 6.00%
TOTALS: 100% 100% 100% 100% 100% 100% 100%
Thus, a perfume selected from the group consisting of Table 1
perfumes A through G is disclosed.
[0121] Suitable perfume raw materials may be obtained from: Symrise
GmbH, with offices located at Muhlenfeldstrasse 1, Holzminden,
37603, Germany; International Flavors & Fragrances Inc., a New
York corporation having an address at 521 W 57th Street, New York,
N.Y. 10019; Givaudan Suisse SA a Swiss corporation having an
address at 1214 Vernier, Switzerland; Firmenich Inc., with offices
located at 250 Plainsboro Rd., Plainsboro Township, N.J. 08536,
United States; and Takasago International Corporation (USA), with
offices located at 4 Volvo Drive, Rockleigh, N.J. 07647, United
States.
Compositions
[0122] The perfumes disclosed in the present specification may be
used in any combination in any type of consumer product, cleaning
and/or treatment composition, fabric and hard surface cleaning
and/or treatment composition, detergent, and highly compact
detergent.
In one aspect, composition comprising a consumer product material
and, based on total composition weight, a perfume raw material
selected from the group consisting of: [0123] a) from about
0.00000001% to about 1%, from about 0.0000001% to about 0.5%, from
about 0.0000005% to about 0.25%, from about 0.000001% to about
0.1%, from about 0.0000025% to about 0.08%, of a perfume raw
material comprising a thiol moiety; [0124] b) from about
0.00000001% to about 1%, from about 0.00000001% to about 0.5%, from
about 0.0000005% to about 0.25%, from about 0.000001% to about
0.1%, from about 0.0000025% to about 0.05%, of a perfume raw
material comprising a sulfide moiety; [0125] c) from about
0.0000001% to about 1%, from about 0.0000005% to about 0.5%, from
about 0.000001% to about 0.25%, from about 0.00050% to about 0.1%,
from about 0.0001% to about 0.01%, of a perfume raw material
comprising a thiazole moiety; [0126] d) from about 0.000000005% to
about 0.5%, from about 0.00000001% to about 0.25%, from about
0.00000005% to about 0.2%, from about 0.0000001% to about 0.1%,
from about 0.0000005% to about 0.05%, of a perfume raw material
comprising a pyrazine moiety; [0127] e) from about 0.000001% to
about 2%, from about 0.00001% to about 1.5%, from about 0.0001% to
about 1%, from about 0.001% to about 0.5%, from about 0.01% to
about 0.25%, of a perfume raw material comprising a nitrile moiety;
[0128] f) from about 0.0000001% to about 1%, from about 0.000001%
to about 0.7%, from about 0.00001% to about 0.4%, from about
0.0001% to about 0.2%, from about 0.001% to about 0.1%, of a
perfume raw material comprising an indole moiety; [0129] g) from
about 0.00000001% to about 1%, from about 0.0000001% to about 0.5%,
from about 0.0000005% to about 0.25%, from about 0.000001% to about
0.1%, from about 0.0000025% to about 0.08%, of a perfume raw
material comprising an oxathiane moiety; [0130] h) from about
0.000001% to about 1%, from about 0.00001% to about 0.75%, from
about 0.0001% to about 0.5%, from about 0.0005% to about 0.25%,
from about 0.001% to about 0.1%, of a perfume raw material
comprising an oxime moiety; [0131] i) from about 0.000001% to about
2%, from about 0.00001% to about 1.5%, from about 0.0001% to about
1%, from about 0.001% to about 0.5%, from about 0.01% to about
0.25%, of a perfume raw material comprising an amine moiety; [0132]
j) from about 0.000000005% to about 0.5%, from about 0.00000001% to
about 0.25%, from about 0.00000005% to about 0.2%, from about
0.0000001% to about 0.1%, from about 0.0000005% to about 0.05%, of
a perfume raw material comprising an isothiocyanate; [0133] k) from
about 0.000000005% to about 0.5%, from about 0.00000001% to about
0.25%, from about 0.00000005% to about 0.2%, from about 0.0000001%
to about 0.1%, from about 0.0000005% to about 0.05%, of a perfume
raw material comprising a diamine moiety; [0134] l) from about
0.0000001% to about 1%, from about 0.0000005% to about 0.5%, from
about 0.000001% to about 0.25%, from about 0.00005% to about 0.1%,
from about 0.0001% to about 0.01%, of a perfume raw material
comprising oxygen, sulfur, and nitrogen; and [0135] m) mixtures
thereof, with the proviso that the sum of the percentage of said
perfume raw materials cannot exceed 100%, is disclosed.
[0136] In one aspect, of said composition, said consumer product
material is selected from the group consisting of an antiperspirant
active, antimicrobial deodorant active, monohydric alcohol,
polyhydric alcohol, petrolatum, an emulsifier, a foaming
surfactant, a hair conditioner, gylcerine and mixtures thereof.
[0137] In one aspect, a composition comprising a consumer product
material and a perfume having:
[0138] a) a two week anti-habituation index of at least 0, 1, 2, 3
or 4;
[0139] b) a four week anti-habituation index of at least 0, 1, 2, 3
or 4;
[0140] c) a two week anti-habituation index of 0, 1, 2, 3, or 4;
and/or
[0141] d) a four week anti-habituation index of 0, 1, 2, 3 or 4
is disclosed.
[0142] In one aspect, a composition comprising a consumer product
material and one or more perfume raw materials, said composition
having:
[0143] a) a two week anti-habituation index of at least 0, 1, 2, 3,
or 4;
[0144] b) a four week anti-habituation index of at least 0, 1, 2, 3
or 4;
[0145] c) a two week anti-habituation index of 0, 1, 2, 3 or 4;
and/or
[0146] d) a four week anti-habituation index of 0, 1, 2, 3 or 4
is disclosed.
[0147] In one aspect, a consumer product comprising, based on total
consumer product weight, from about 0.0001% to about 100% of a neat
perfume and/or perfume raw disclosed herein, the balance of said
consumer product comprising an adjunct ingredient and/or a perfume
delivery system comprising a perfume, an encapsulate disclosed
herein, a cyclic oligosaccharide complex disclosed herein and/or a
perfume raw material disclosed herein, is disclosed.
[0148] In one aspect, a cleaning and/or treatment composition
comprising based on total cleaning and treatment products weight
from about 0.0001% to about 25% of a perfume, an encapsulate
disclosed herein, a cyclic oligosaccharide complex disclosed herein
and/or perfume raw disclosed herein and an adjunct ingredient is
disclosed.
[0149] In one aspect, a fabric and/or hard surface cleaning and/or
treatment composition comprising, based on total fabric and/or hard
surface cleaning and/or treatment composition weight of from about
0.00001% to about 25% of a perfume an encapsulate disclosed herein,
a cyclic oligosaccharide complex disclosed herein and/or perfume
raw disclosed herein and an adjunct ingredient, is disclosed.
[0150] In one aspect, a detergent comprising, based on total fabric
and/or hard surface cleaning and/or treatment composition weight of
from about 0.00001% to about 25% of a perfume, an encapsulate
disclosed herein, a cyclic oligosaccharide complex disclosed herein
and/or perfume raw disclosed herein and an adjunct ingredient, is
disclosed.
[0151] In one aspect, a highly compacted consumer product
comprising, based on total highly compacted consumer product
composition weight, from about 0.00001% to about 25% of a perfume,
an encapsulate disclosed herein, a cyclic oligosaccharide complex
disclosed herein and/or perfume raw disclosed herein and an adjunct
ingredient, is disclosed.
[0152] In one aspect, a consumer product comprising, based on total
consumer product weight, from about 0.0001% to about 100% of a neat
perfume, and/or perfume raw disclosed herein, the balance of said
consumer product comprising an adjunct ingredient and/or a perfume
delivery system comprising a perfume and/or perfume raw disclosed
herein, is disclosed.
[0153] In one aspect, a cleaning and/or treatment composition
comprising based on total cleaning and treatment composition weight
from about 0.0001% to about 25% of a perfume, and/or perfume raw
disclosed herein and an adjunct ingredient, is disclosed.
[0154] In one aspect, a fabric and/or hard surface cleaning and/or
treatment composition comprising, based on total fabric and/or hard
surface cleaning and/or treatment composition weight, from about
0.00001% to about 25% of a perfume, and/or perfume raw disclosed
herein and an adjunct ingredient, is disclosed.
[0155] In one aspect, a detergent comprising based on total
detergent weight of from about 0.00001% to about 25% of a perfume,
and/or perfume raw disclosed herein and an adjunct ingredient, is
disclosed.
[0156] In one aspect, a highly compacted consumer product
comprising, based on total highly compacted consumer product
weight, from about 0.00001% to about 25% of a perfume, and/or
perfume raw disclosed herein and an adjunct ingredient, is
disclosed.
[0157] In one aspect, a deodorant comprising a perfume, an
encapsulate disclosed herein, a cyclic oligosaccharide complex
disclosed herein and/or perfume raw disclosed herein and, based on
total deodorant weight, from about 0.01% to about 75% of an
antimicrobial, is disclosed.
[0158] In one aspect, said deodorant comprises, based on total
deodorant weight, from about 10% to about 75% glycol.
[0159] In one aspect, an antiperspirant comprising a perfume, an
encapsulate disclosed herein, a cyclic oligosaccharide complex
disclosed herein and/or perfume raw disclosed herein and, based on
total composition weight, from about 1% to about 25% of an aluminum
salt antiperspirant active, is disclosed.
[0160] In one aspect, a body wash/shampoo comprising a perfume, an
encapsulate disclosed herein, a cyclic oligosaccharide complex
disclosed herein and/or perfume raw disclosed herein and a
miscellar phase and/or lamellar phase, is disclosed.
[0161] In one aspect, a lotion comprising a perfume, an encapsulate
disclosed herein, a cyclic oligosaccharide complex disclosed herein
and/or perfume raw disclosed herein and a humectants, is
disclosed.
[0162] In one aspect, said lotion comprises glycerin.
[0163] In one aspect, a fabric care composition comprising a
perfume, an encapsulate disclosed herein, a cyclic oligosaccharide
complex disclosed herein and/or perfume raw disclosed herein, said
fabric care composition being selected from the group consisting of
detergents, fabric softeners, and laundry additives, [0164] a) said
detergent being: [0165] (i) a liquid detergent comprising a
material selected from an anti-redep polymer, an enzyme, a
structurant and mixtures thereof; [0166] (ii) a powder or granule
detergent comprising a material selected from the group consisting
of an anti-redep polymer, an enzymes, a bleach and mixtures
thereof; [0167] (iii) a unit dose comprising a material selected
from the group consisting of an anti-redep polymer, an enzymes, a
bleach, a soluble substrate/film and mixtures thereof [0168] b)
said fabric softener being a liquid, powder or sheet comprising a
fabric softener active and an optional structurant; [0169] c) said
laundry additive being: [0170] (i) a bleach additive comprising a
material selected from the group consisting of hypochlorite,
hydrogen peroxide and mixtures thereof; [0171] (ii) a pretreater
comprising a material selected from the group consisting of an
effervescent, a propellant and mixtures thereof; and [0172] (iii)
an in-wash boosters comprising a material selected from the group
consisting of an enzyme, a non-chlorine bleach and mixtures thereof
[0173] is disclosed.
[0174] In one aspect, a home care composition comprising a perfume,
an encapsulate disclosed herein, a cyclic oligosaccharide complex
disclosed herein and/or perfume raw disclosed herein, said home
care composition being selected from the group consisting of an
automatic dish washing composition, a hand dish washing
composition, a hard surface cleaning composition and an air care
composition, [0175] a) said automatic dish washing composition
being: [0176] (i) a liquid or gel comprising a material selected
from an anti-redep polymer, an enzyme, a structurant, a
shine/sheeting polymer and mixtures thereof; [0177] (ii) a powder
or granule comprising a material selected from the group consisting
of an anti-redep polymer, an enzyme, a bleach, a shine/sheeting
polymer and mixtures thereof; [0178] (iii) a unit dose comprising a
material selected from the group consisting of an anti-redep
polymer, an enzymes, a bleach, a shine/sheeting polymer, a soluble
substrate/film and mixtures thereof [0179] b) said hand dish
washing composition comprising a material selected from the group
consisting of a anti-bacterial, a hand/skin softener,
shine/sheeting polymers and mixtures thereof; [0180] c) said hard
surface cleaning composition comprising a material selected from
the group consisting of an anti-bacterial, a strong acid,
preferably selected from the group consisting of glycolic acid,
citric acid and mixtures thereof, etc., a strong base, preferably
selected from the group consisting of a Na hydroxides, a Li
hydroxide and mixtures thereof, an effervescent, a propellants, a
shine/sheeting polymers and mixtures thereof; [0181] d) an air care
composition comprising a malodor control composition that comprises
zinc, cyclodextrin, a propellant and/or mixtures thereof [0182] is
disclosed.
[0183] A consumer product comprising, based on total consumer
product weight, from about 0.0001% to about 100% of a neat perfume
selected from the group consisting of Table 1 perfumes A through G,
the balance of consumer product comprising an adjunct ingredient,
and/or a perfume delivery system comprising a Table 1 perfume is
also disclosed.
[0184] A cleaning and/or treatment composition comprising based on
total cleaning and treatment products weight from about 0.0001% to
about 25% of a perfume selected from the group consisting of Table
1 perfumes A through G and an adjunct ingredient is also
disclosed.
[0185] A fabric and/or hard surface cleaning and/or treatment
composition comprising, based on total fabric and/or hard surface
cleaning and/or treatment composition weight of from about 0.00001%
to about 25% of a perfume selected from the group consisting of
Table 1 perfumes A through G and an adjunct ingredient is also
disclosed.
[0186] A detergent comprising, based on total fabric and/or hard
surface cleaning and/or treatment composition weight of from about
0.00001% to about 25% of a perfume selected from the group
consisting of Table 1 perfumes A through G and an adjunct
ingredient is also disclosed.
[0187] A highly compacted consumer product comprising, based on
total highly compacted consumer product composition weight, from
about 0.00001% to about 25% of a perfume selected from the group
consisting of Table 1 perfumes A through G and an adjunct
ingredient is also disclosed.
[0188] A consumer product comprising, based on total consumer
product weight, from about 0.0001% to about 100% of a neat perfume
selected from the group consisting of Table 1 perfumes A through G,
the balance of said consumer product comprising an adjunct
ingredient, and/or a perfume delivery system comprising a one or
more Table 1 perfume raw materials is also disclosed.
[0189] A cleaning and/or treatment composition comprising based on
total composition weight, from about 0.0001% to about 25% of a
perfume selected from the group consisting of Table 1 perfumes A
through G and an adjunct ingredient is also disclosed.
[0190] A fabric and/or hard surface cleaning and/or treatment
composition comprising, based on total composition weight, from
about 0.00001% to about 25% of a perfume selected from the group
consisting of Table 1 perfumes A through G and an adjunct
ingredient is also disclosed.
[0191] A detergent comprising, based on total detergent weight,
from about 0.00001% to about 25% of a perfume selected from the
group consisting of Table 1 perfumes A through G and an adjunct
ingredient is also disclosed.
[0192] A highly compacted consumer product comprising, based on
total highly compacted consumer product composition weight, from
about 0.00001% to about 25% of a perfume selected from the group
consisting of Table 1 perfumes A through G and an adjunct
ingredient is also disclosed.
[0193] A deodorant comprising, based on total deodorant weight,
from about 0.01% to about 75% of an antimicrobial and a perfume
selected from the group consisting of Table 1 perfumes A through G
is also disclosed. In one aspect, said deodorant comprises, based
on total deodorant weight, from about 10% to about 75% glycol.
[0194] An antiperspirant comprising based on total antiperspirant
weight, from about 1% to about 25% of an aluminum salt
antiperspirant active and a perfume selected from the group
consisting of Table 1 perfumes A through G is also disclosed.
[0195] A body wash/shampoo comprising a perfume selected from the
group consisting of Table 1 perfumes A through G and a miscellar
phase and/or lamellar phase is also disclosed.
[0196] A lotion comprising a perfume selected from the group
consisting of Table 1 perfumes A through G and a humectant is also
disclosed. In one aspect, said humectant comprises glycerin.
[0197] A fabric care composition comprising a perfume selected from
the group consisting of Table 1 perfumes A through G, said fabric
care composition being selected from the group consisting of
detergents, fabric softeners, and laundry additives, [0198] a) said
detergent being: [0199] (i) a liquid detergent comprising a
material selected from an anti-redep polymer, an enzyme, a
structurant and mixtures thereof; [0200] (ii) a powder or granule
detergent comprising a material selected from the group consisting
of an anti-redep polymer, an enzymes, a bleach and mixtures
thereof; [0201] (iii) a unit dose comprising a material selected
from the group consisting of an anti-redep polymer, an enzymes, a
bleach, a soluble substrate/film and mixtures thereof; [0202] b)
said fabric softener being a liquid, powder or sheet comprising a
fabric softener active and an optional structurant; [0203] c) said
laundry additive being: [0204] (i) a bleach additive comprising a
material selected from the group consisting of hypochlorite,
hydrogen peroxide and mixtures thereof; [0205] (ii) a pretreater
comprising a material selected from the group consisting of an
effervescent, a propellant and mixtures thereof; and [0206] (iii)
an in-wash boosters comprising a material selected from the group
consisting of an enzyme, a non-chlorine bleach and mixtures
thereof
[0207] is also disclosed.
[0208] A home care composition comprising a perfume selected from
the group consisting of Table 1 perfumes A through G, said home
care composition being selected from the group consisting of an
automatic dish washing composition, a hand dish washing
composition, a hard surface cleaning composition and an air care
composition, [0209] a) said automatic dish washing composition
being: [0210] (i) a liquid or gel comprising a material selected
from an anti-redep polymer, an enzyme, a structurant, a
shine/sheeting polymer and mixtures thereof; [0211] (ii) a powder
or granule comprising a material selected from the group consisting
of an anti-redep polymer, an enzyme, a bleach, a shine/sheeting
polymer and mixtures thereof; [0212] (iii) a unit dose comprising a
material selected from the group consisting of an anti-redep
polymer, an enzymes, a bleach, a shine/sheeting polymer, a soluble
substrate/film and mixtures thereof [0213] b) said hand dish
washing composition comprising a material selected from the group
consisting of a anti-bacterial, a hand/skin softener,
shine/sheeting polymers and mixtures thereof; [0214] c) said hard
surface cleaning composition comprising a material selected from
the group consisting of an anti-bacterial, a strong acid,
preferably selected from the group consisting of glycolic acid,
citric acid and mixtures thereof, etc., a strong base, preferably
selected from the group consisting of Na hydroxides, a Li hydroxide
and mixtures thereof, an effervescent, a propellants, a
shine/sheeting polymers and mixtures thereof; [0215] d) an air care
composition comprising a malodor control composition that comprises
zinc, cyclodextrin, a propellant and/or mixtures thereof
[0216] is also disclosed.
[0217] Air Care Devices
[0218] As the perfumes disclosed herein are not habituating, such
perfumes may be used without resorting to switching the perfumes as
is common in air care devices so that the consumer does not become
habituated. The present invention relates to an apparatus for the
delivery of a volatile material to the atmosphere. It is
contemplated that the apparatus may be configured for use in a
variety of applications to deliver volatile materials to the
atmosphere. Suitable devices include those devices disclosed in
USPA 2012/0228402 A1 and USPA 2010/0308130 A1 both publications
which are herein expressly incorporated by reference.
[0219] For example, the apparatus may be configured for use with an
energized device. An exemplary energized device may be an
electrical heating device. More particularly, the device may be an
electrical wall plug air freshener as described in U.S. Pat. No.
7,223,361; a battery powered heating device; or other heating
devices (e.g. devices powered by chemical reactions such as
catalyst fuel systems; solar powered devices, etc.). In such
devices, the volatile material delivery engine may be placed next
to the heating surface to diffuse the volatile material. The
volatile material formula may be adjusted to include an overall
lower vapor pressure formula.
[0220] The apparatus may also be configured for use with an air
purifying system to deliver both purified air and volatile
materials to the atmosphere. Non-limiting examples include air
purifying systems using ionization and/or filtration technology for
use in small spaces (e.g. bedrooms, bathrooms, automobiles, etc.),
and whole house central air conditioning/heating systems (e.g.
HVAC).
[0221] The apparatus may also be configured for use with an aerosol
or non-aerosol air spray. In this embodiment, the delivery engine
can deliver volatile materials upon user demand or programmed to
automatically deliver volatile materials to the atmosphere.
[0222] The apparatus may also be configured for use with a fan to
deliver volatile materials to the atmosphere.
[0223] In one aspect, an apparatus for delivering a volatile
material comprising a delivery engine having a liquid reservoir for
containing a volatile material comprising a single opening; a
rupturable substrate enclosing the single opening; a rupture
element; a collection basin in fluid communication with the liquid
reservoir upon rupturing the rupturable substrate; and a breathable
membrane enclosing the liquid reservoir, rupturable substrate,
rupture element, and collection basin is disclosed. The breathable
membrane has an evaporative surface area of about 2 cm.sup.2 to
about 35 cm.sup.2 and has an average pore size of about 0.02
microns. The apparatus also comprises a housing for receiving and
releasably engaging the delivery system. The housing has a rib for
guiding the delivery engine and a notch for compressing the rupture
element upon insertion of the delivery engine into the housing.
[0224] FIGS. 1-3 depict an air care device that is suitable for use
with the perfumes and compositions disclosed herein. As shown in
FIGS. 1-3, the device 20 comprises a housing 22, and the housing 22
is supported on an electrical outlet 24 by a plug 26 that is at
least indirectly joined to the housing 22. The device 20 further
comprises at least one container. In the embodiment shown in FIGS.
1-3, the device 20 comprises two containers 28 and 30. The
containers 28 and 30 contain at least a first volatile composition
32 and a second volatile composition 34. The housing 22 may serve
as a holder for the containers 28 and 30 and any of the other
components of the device described below.
[0225] In one aspect, an air care device that comprises one chamber
said chamber comprising a perfume and/or a perfume raw material
disclosed herein is disclosed. In one aspect, an air care device
that comprises more than one chamber, at least one of said chambers
comprising a perfume and/or a perfume raw material disclosed herein
is disclosed.
Perfume Delivery Systems
[0226] Certain perfume delivery systems, methods of making certain
perfume delivery systems and the uses of such perfume delivery
systems are disclosed in USPA 2007/0275866 A1. The perfumes and
PRMs disclosed herein may be used in such perfume delivery systems.
Such perfume delivery systems include:
I. Polymer Assisted Delivery (PAD):
[0227] This perfume delivery technology uses polymeric materials to
deliver perfume materials. Classical coacervation, water soluble or
partly soluble to insoluble charged or neutral polymers, liquid
crystals, hot melts, hydrogels, perfumed plastics, microcapsules,
nano- and micro-latexes, polymeric film formers, and polymeric
absorbents, polymeric adsorbents, etc. are some examples. PAD
includes but is not limited to: [0228] a.) Matrix Systems: The
fragrance is dissolved or dispersed in a polymer matrix or
particle. Perfumes, for example, may be 1) dispersed into the
polymer prior to formulating into the product or 2) added
separately from the polymer during or after formulation of the
product. Diffusion of perfume from the polymer is a common trigger
that allows or increases the rate of perfume release from a
polymeric matrix system that is deposited or applied to the desired
surface (situs), although many other triggers are know that may
control perfume release. Absorption and/or adsorption into or onto
polymeric particles, films, solutions, and the like are aspects of
this technology. Nano- or micro-particles composed of organic
materials (e.g., latexes) are examples. Suitable particles include
a wide range of materials including, but not limited to polyacetal,
polyacrylate, polyacrylic, polyacrylonitrile, polyamide,
polyaryletherketone, polybutadiene, polybutylene, polybutylene
terephthalate, polychloroprene, poly ethylene, polyethylene
terephthalate, polycyclohexylene dimethylene terephthalate,
polycarbonate, polychloroprene, polyhydroxyalkanoate, polyketone,
polyester, polyethylene, polyetherimide, polyethersulfone,
polyethylenechlorinates, polyimide, polyisoprene, polylactic acid,
polymethylpentene, polyphenylene oxide, polyphenylene sulfide,
polyphthalamide, polypropylene, polystyrene, polysulfone, polyvinyl
acetate, polyvinyl chloride, as well as polymers or copolymers
based on acrylonitrile-butadiene, cellulose acetate, ethylene-vinyl
acetate, ethylene vinyl alcohol, styrene-butadiene, vinyl
acetate-ethylene, and mixtures thereof. [0229] "Standard" systems
refer to those that are "pre-loaded" with the intent of keeping the
pre-loaded perfume associated with the polymer until the moment or
moments of perfume release. Such polymers may also suppress the
neat product odor and provide a bloom and/or longevity benefit
depending on the rate of perfume release. One challenge with such
systems is to achieve the ideal balance between 1) in-product
stability (keeping perfume inside carrier until you need it) and 2)
timely release (during use or from dry situs). Achieving such
stability is particularly important during in-product storage and
product aging. This challenge is particularly apparent for
aqueous-based, surfactant-containing products, such as heavy duty
liquid laundry detergents. Many "Standard" matrix systems available
effectively become "Equilibrium" systems when formulated into
aqueous-based products. One may select an "Equilibrium" system or a
Reservoir system, which has acceptable in-product diffusion
stability and available triggers for release (e.g., friction).
"Equilibrium" systems are those in which the perfume and polymer
may be added separately to the product, and the equilibrium
interaction between perfume and polymer leads to a benefit at one
or more consumer touch points (versus a free perfume control that
has no polymer-assisted delivery technology). The polymer may also
be pre-loaded with perfume; however, part or all of the perfume may
diffuse during in-product storage reaching an equilibrium that
includes having desired perfume raw materials (PRMs) associated
with the polymer. The polymer then carries the perfume to the
surface, and release is typically via perfume diffusion. The use of
such equilibrium system polymers has the potential to decrease the
neat product odor intensity of the neat product (usually more so in
the case of pre-loaded standard system). Deposition of such
polymers may serve to "flatten" the release profile and provide
increased longevity. As indicated above, such longevity would be
achieved by suppressing the initial intensity and may enable the
formulator to use more high impact or low odor detection threshold
(ODT) or low Kovats Index (KI) PRMs to achieve FMOT benefits
without initial intensity that is too strong or distorted. It is
important that perfume release occurs within the time frame of the
application to impact the desired consumer touch point or touch
points. Suitable micro-particles and micro-latexes as well as
methods of making same may be found in USPA 2005/0003980 A1. Matrix
systems also include hot melt adhesives and perfume plastics. In
addition, hydrophobically modified polysaccharides may be
formulated into the perfumed product to increase perfume deposition
and/or modify perfume release. All such matrix systems, including
for example polysaccharides and nanolatexes may be combined with
other PDTs, including other PAD systems such as PAD reservoir
systems in the form of a perfume microcapsule (PMC). Polymer
Assisted Delivery (PAD) matrix systems may include those described
in the following references: US Patent Application 2004/0110648 A1
and U.S. Pat. No. 6,531,444. [0230] Silicones are also examples of
polymers that may be used as PDT, and can provide perfume benefits
in a manner similar to the polymer-assisted delivery "matrix
system". Such a PDT is referred to as silicone-assisted delivery
(SAD). One may pre-load silicones with perfume, or use them as an
equilibrium system as described for PAD. Suitable silicones as well
as making same may be found in USPA 20050143282A1. Functionalized
silicones may also be used as described in USPA 2006/003913 A1.
Examples of silicones include polydimethylsiloxane and
polyalkyldimethylsiloxanes. Other examples include those with amine
functionality, which may be used to provide benefits associated
with amine-assisted delivery (AAD) and/or polymer-assisted delivery
(PAD) and/or amine-reaction products (ARP). Other such examples may
be found in USPA 2005/0003980 A1. [0231] b.) Reservoir Systems:
Reservoir systems are also known as a core-shell type technology,
or one in which the fragrance is surrounded by a perfume release
controlling membrane, which may serve as a protective shell. The
material inside the microcapsule is referred to as the core,
internal phase, or fill, whereas the wall is sometimes called a
shell, coating, or membrane. Microparticles or pressure sensitive
capsules or microcapsules are examples of this technology.
Microcapsules of the current invention are formed by a variety of
procedures that include, but are not limited to, coating,
extrusion, spray-drying, interfacial, in-situ and matrix
polymerization. The possible shell materials vary widely in their
stability toward water. Among the most stable are
polyoxymethyleneurea (PMU)-based materials, which may hold certain
PRMs for even long periods of time in aqueous solution (or
product). Such systems include but are not limited to
urea-formaldehyde and/or melamine-formaldehyde. Gelatin-based
microcapsules may be prepared so that they dissolve quickly or
slowly in water, depending for example on the degree of
cross-linking. Many other capsule wall materials are available and
vary in the degree of perfume diffusion stability observed. Without
wishing to be bound by theory, the rate of release of perfume from
a capsule, for example, once deposited on a surface is typically in
reverse order of in-product perfume diffusion stability. As such,
urea-formaldehyde and melamine-formaldehyde microcapsules for
example, typically require a release mechanism other than, or in
addition to, diffusion for release, such as mechanical force (e.g.,
friction, pressure, shear stress) that serves to break the capsule
and increase the rate of perfume (fragrance) release. Other
triggers include melting, dissolution, hydrolysis or other chemical
reaction, electromagnetic radiation, and the like. Suitable capsule
wall materials include, in addition to aminoplasts, polyvinyl
alcohol, polyvinyl pyrrolidone, polyethylene glycol,
polysaccharides and modified polysaccharides, gel forming proteins,
modified celluloses such as carboxymethylcelluloses and
hydroxyethylcelluloses, polyacrylates, polyureas, polyurethanes and
mixtures thereof. The capsules may be further coated with an
additional coating that can improve the deposition and/or retention
of the capsule on the desired surface. Suitable coating materials
include a cationic polymer selected from the group consisting of
selected from the group consisting of polysaccharides, cationically
modified starch, cationically modified guar, polysiloxanes, poly
diallyl dimethyl ammonium halides, copolymers of poly diallyl
dimethyl ammonium chloride and vinyl pyrrolidone, acrylamides,
imidazoles, imidazolinium halides, imidazolium halides, poly vinyl
amine, copolymers of poly vinyl amine and N-vinyl formamide to the
surface of the capsule to form a cationically coated polymer
encapsulated material. Typical capsules have a diameter of 1 micron
to 500 microns. The use of pre-loaded microcapsules requires the
proper ratio of in-product stability and in-use and/or on-surface
(on-situs) release, as well as proper selection of PRMs.
Microcapsules that are based on urea-formaldehyde and/or
melamine-formaldehyde are relatively stable, especially in near
neutral aqueous-based solutions. These materials may require a
friction trigger which may not be applicable to all product
applications. Other microcapsule materials (e.g., gelatin) may be
unstable in aqueous-based products and may even provide reduced
benefit (versus free perfume control) when in-product aged.
II. Molecule-Assisted Delivery (MAD):
[0232] Non-polymer materials or molecules may also serve to improve
the delivery of perfume. Without wishing to be bound by theory,
perfume may non-covalently interact with organic materials,
resulting in altered deposition and/or release. Non-limiting
examples of such organic materials include but are not limited to
hydrophobic materials such as organic oils, waxes, mineral oils,
petrolatum, fatty acids or esters, sugars, surfactants, liposomes
and even other perfume raw material (perfume oils), as well as
natural oils, including body and/or other soils. Perfume fixatives
are yet another example. In one aspect, non-polymeric materials or
molecules have a CLogP greater than about 2. Molecule-Assisted
Delivery (MAD) may also include those described in U.S. Pat. No.
7,119,060.
III. Fiber-Assisted Delivery (FAD):
[0233] The choice or use of a situs itself may serve to improve the
delivery of perfume. In fact, the situs itself may be a perfume
delivery technology. For example, different fabric types such as
cotton or polyester will have different properties with respect to
ability to attract and/or retain and/or release perfume. The amount
of perfume deposited on or in fibers may be altered by the choice
of fiber, and also by the history or treatment of the fiber, as
well as by any fiber coatings or treatments. Fibers may be woven
and non-woven as well as natural or synthetic. Natural fibers
include those produced by plants, animals, and geological
processes, and include but are not limited to cellulose materials
such as cotton, linen, hemp jute, flax, ramie, and sisal, and
fibers used to manufacture paper and cloth. Fiber-Assisted Delivery
may consist of the use of wood fiber, such as thermomechanical pulp
and bleached or unbleached kraft or sulfite pulps. Animal fibers
consist largely of particular proteins, such as silk, sinew, catgut
and hair (including wool). Polymer fibers based on synthetic
chemicals include but are not limited to polyamide nylon, PET or
PBT polyester, phenol-formaldehyde (PF), polyvinyl alcohol fiber
(PVOH), polyvinyl chloride fiber (PVC), polyolefins (PP and PE),
and acrylic polymers. All such fibers may be pre-loaded with a
perfume, and then added to a product that may or may not contain
free perfume and/or one or more perfume delivery technologies. In
one aspect, the fibers may be added to a product prior to being
loaded with a perfume, and then loaded with a perfume by adding a
perfume that may diffuse into the fiber, to the product. Without
wishing to be bound by theory, the perfume may absorb onto or be
adsorbed into the fiber, for example, during product storage, and
then be released at one or more moments of truth or consumer touch
points.
IV. Amine Assisted Delivery (AAD):
[0234] The amine-assisted delivery technology approach utilizes
materials that contain an amine group to increase perfume
deposition or modify perfume release during product use. There is
no requirement in this approach to pre-complex or pre-react the
perfume raw material(s) and amine prior to addition to the product.
In one aspect, amine-containing AAD materials suitable for use
herein may be non-aromatic; for example, polyalkylimine, such as
polyethyleneimine (PEI), or polyvinylamine (PVAm), or aromatic, for
example, anthranilates. Such materials may also be polymeric or
non-polymeric. In one aspect, such materials contain at least one
primary amine. This technology will allow increased longevity and
controlled release also of low ODT perfume notes (e.g., aldehydes,
ketones, enones) via amine functionality, and delivery of other
PRMs, without being bound by theory, via polymer-assisted delivery
for polymeric amines. Without technology, volatile top notes can be
lost too quickly, leaving a higher ratio of middle and base notes
to top notes. The use of a polymeric amine allows higher levels of
top notes and other PRMS to be used to obtain freshness longevity
without causing neat product odor to be more intense than desired,
or allows top notes and other PRMs to be used more efficiently. In
one aspect, AAD systems are effective at delivering PRMs at pH
greater than about neutral. Without wishing to be bound by theory,
conditions in which more of the amines of the AAD system are
deprotonated may result in an increased affinity of the
deprotonated amines for PRMs such as aldehydes and ketones,
including unsaturated ketones and enones such as damascone. In
another aspect, polymeric amines are effective at delivering PRMs
at pH less than about neutral. Without wishing to be bound by
theory, conditions in which more of the amines of the AAD system
are protonated may result in a decreased affinity of the protonated
amines for PRMs such as aldehydes and ketones, and a strong
affinity of the polymer framework for a broad range of PRMs. In
such an aspect, polymer-assisted delivery may be delivering more of
the perfume benefit; such systems are a subspecies of AAD and may
be referred to as Amine-Polymer-Assisted Delivery or APAD. In some
cases when the APAD is employed in a composition that has a pH of
less than seven, such APAD systems may also be considered
Polymer-Assisted Delivery (PAD). In yet another aspect, AAD and PAD
systems may interact with other materials, such as anionic
surfactants or polymers to form coacervate and/or coacervates-like
systems. In another aspect, a material that contains a heteroatom
other than nitrogen, for example sulfur, phosphorus or selenium,
may be used as an alternative to amine compounds. In yet another
aspect, the aforementioned alternative compounds can be used in
combination with amine compounds. In yet another aspect, a single
molecule may comprise an amine moiety and one or more of the
alternative heteroatom moieties, for example, thiols, phosphines
and selenols. Suitable AAD systems as well as methods of making
same may be found in U.S. Pat. No. 6,103,678.
V. Cyclodextrin Delivery System (CD):
[0235] This technology approach uses a cyclic oligosaccharide or
cyclodextrin to improve the delivery of perfume. Typically a
perfume and cyclodextrin (CD) complex is formed. Such complexes may
be preformed, formed in-situ, or formed on or in the situs. Without
wishing to be bound by theory, loss of water may serve to shift the
equilibrium toward the CD-Perfume complex, especially if other
adjunct ingredients (e.g., surfactant) are not present at high
concentration to compete with the perfume for the cyclodextrin
cavity. A bloom benefit may be achieved if water exposure or an
increase in moisture content occurs at a later time point. In
addition, cyclodextrin allows the perfume formulator increased
flexibility in selection of PRMs. Cyclodextrin may be pre-loaded
with perfume or added separately from perfume to obtain the desired
perfume stability, deposition or release benefit. Suitable CDs as
well as methods of making same may be found in USPA 2006/0263313
A1.
VI. Starch Encapsulated Accord (SEA):
[0236] The use of a starch encapsulated accord (SEA) technology
allows one to modify the properties of the perfume, for example, by
converting a liquid perfume into a solid by adding ingredients such
as starch. The benefit includes increased perfume retention during
product storage, especially under non-aqueous conditions. Upon
exposure to moisture, a perfume bloom may be triggered. Benefits at
other moments of truth may also be achieved because the starch
allows the product formulator to select PRMs or PRM concentrations
that normally cannot be used without the presence of SEA. Another
technology example includes the use of other organic and inorganic
materials, such as silica to convert perfume from liquid to solid.
Suitable SEAs as well as methods of making same may be found in
U.S. Pat. No. 6,458,754 B1.
VII. Inorganic Carrier Delivery System (ZIC):
[0237] This technology relates to the use of porous zeolites or
other inorganic materials to deliver perfumes. Perfume-loaded
zeolite may be used with or without adjunct ingredients used for
example to coat the perfume-loaded zeolite (PLZ) to change its
perfume release properties during product storage or during use or
from the dry situs. Suitable zeolite and inorganic carriers as well
as methods of making same may be found in USPA 2005/0003980 A1.
Silica is another form of ZIC. Another example of a suitable
inorganic carrier includes inorganic tubules, where the perfume or
other active material is contained within the lumen of the nano- or
micro-tubules. Preferably, the perfume-loaded inorganic tubule (or
Perfume-Loaded Tubule or PLT) is a mineral nano- or micro-tubule,
such as halloysite or mixtures of halloysite with other inorganic
materials, including other clays. The PLT technology may also
comprise additional ingredients on the inside and/or outside of the
tubule for the purpose of improving in-product diffusion stability,
deposition on the desired situs or for controlling the release rate
of the loaded perfume. Monomeric and/or polymeric materials,
including starch encapsulation, may be used to coat, plug, cap, or
otherwise encapsulate the PLT. Suitable PLT systems as well as
methods of making same may be found in U.S. Pat. No. 5,651,976.
VIII. Pro-Perfume (PP):
[0238] This technology refers to perfume technologies that result
from the reaction of perfume materials with other substrates or
chemicals to form materials that have a covalent bond between one
or more PRMs and one or more carriers. The PRM is converted into a
new material called a pro-PRM (i.e., pro-perfume), which then may
release the original PRM upon exposure to a trigger such as water
or light. Pro-perfumes may provide enhanced perfume delivery
properties such as increased perfume deposition, longevity,
stability, retention, and the like. Pro-perfumes include those that
are monomeric (non-polymeric) or polymeric, and may be pre-formed
or may be formed in-situ under equilibrium conditions, such as
those that may be present during in-product storage or on the wet
or dry situs. Nonlimiting examples of pro-perfumes include Michael
adducts (e.g., beta-amino ketones), aromatic or non-aromatic imines
(Schiffs Bases), oxazolidines, beta-keto esters, and orthoesters.
Another aspect includes compounds comprising one or more beta-oxy
or beta-thio carbonyl moieties capable of releasing a PRM, for
example, an alpha, beta-unsaturated ketone, aldehyde or carboxylic
ester. The typical trigger for perfume release is exposure to
water; although other triggers may include enzymes, heat, light, pH
change, autoxidation, a shift of equilibrium, change in
concentration or ionic strength and others. For aqueous-based
products, light-triggered pro-perfumes are particularly suited.
Such photo-pro-perfumes (PPPs) include but are not limited to those
that release coumarin derivatives and perfumes and/or pro-perfumes
upon being triggered. The released pro-perfume may release one or
more PRMs by means of any of the above mentioned triggers. In one
aspect, the photo-pro-perfume releases a nitrogen-based pro-perfume
when exposed to a light and/or moisture trigger. In another aspect,
the nitrogen-based pro-perfume, released from the
photo-pro-perfume, releases one or more PRMs selected, for example,
from aldehydes, ketones (including enones) and alcohols. In still
another aspect, the PPP releases a dihydroxy coumarin derivative.
The light-triggered pro-perfume may also be an ester that releases
a coumarin derivative and a perfume alcohol. In one aspect the
pro-perfume is a dimethoxybenzoin derivative as described in USPA
2006/0020459 A1. In another aspect the pro-perfume is a
3',5'-dimethoxybenzoin (DMB) derivative that releases an alcohol
upon exposure to electromagnetic radiation. In yet another aspect,
the pro-perfume releases one or more low ODT PRMs, including
tertiary alcohols such as linalool, tetrahydrolinalool, or
dihydromyrcenol. Suitable pro-perfumes and methods of making same
can be found in U.S. Pat. No. 7,018,978 B2. [0239] a.) Amine
Reaction Product (ARP): For purposes of the present application,
ARP is a subclass or species of PP. One may also use "reactive"
polymeric amines in which the amine functionality is pre-reacted
with one or more PRMs to form an amine reaction product (ARP).
Typically the reactive amines are primary and/or secondary amines,
and may be part of a polymer or a monomer (non-polymer). Such ARPs
may also be mixed with additional PRMs to provide benefits of
polymer-assisted delivery and/or amine-assisted delivery.
Nonlimiting examples of polymeric amines include polymers based on
polyalkylimines, such as polyethyleneimine (PEI), or polyvinylamine
(PVAm). Nonlimiting examples of monomeric (non-polymeric) amines
include hydroxylamines, such as 2-aminoethanol and its alkyl
substituted derivatives, and aromatic amines such as anthranilates.
The ARPs may be premixed with perfume or added separately in
leave-on or rinse-off applications. In another aspect, a material
that contains a heteroatom other than nitrogen, for example oxygen,
sulfur, phosphorus or selenium, may be used as an alternative to
amine compounds. In yet another aspect, the aforementioned
alternative compounds can be used in combination with amine
compounds. In yet another aspect, a single molecule may comprise an
amine moiety and one or more of the alternative heteroatom
moieties, for example, thiols, phosphines and selenols. The benefit
may include improved delivery of perfume as well as controlled
perfume release. Suitable ARPs as well as methods of making same
can be found in U.S. Pat. No. 6,413,920 B1. [0240] b.)
Sulfur-containing Pro-perfume Compound
[0241] The embodiments of the perfumes disclosed herein can be used
as the perfume component pro-perfume compounds that contain sulfur.
The term "pro-perfume compound" herein refers to compounds
resulting from the chemical bonding of perfume raw materials (PRMs)
with materials that comprise sulfur. The pro-perfume compound can
release the original PRM (i.e., pre-converted) upon exposure to a
trigger such as water or light or atmospheric oxygen. Suitable
methods of making the same can be found in U.S. Pat. No.
7,018,978.
[0242] Amounts of Perfumes and PRMs Used In Delivery Systems
[0243] In one aspect, the perfumes and PRM disclosed herein,
including those in Table 1, and stereoisomers thereof are suitable
for use, in perfume delivery systems at levels, based on total
perfume delivery system weight, of from 0.001% to about 50%, from
0.005% to 30%, from 0.01% to about 10%, from 0.025% to about 5%, or
even from 0.025% to about 1%.
[0244] In one aspect, the perfume delivery systems disclosed herein
are suitable for use in consumer products, cleaning and treatment
compositions and fabric and hard surface cleaning and/or treatment
compositions, detergents, and highly compacted consumer products,
including highly compacted fabric and hard surface cleaning and/or
treatment compositions, for example highly compacted detergents
that may be solids or fluids, at levels, based on total consumer
product weight, from about 0.001% to about 20%, from about 0.01% to
about 10%, from about 0.05% to about 5%, from about 0.1% to about
0.5%.
[0245] In one aspect, the amount of the perfumes and PRM disclosed
herein, including those Table 1 PRMs, based on the total
microcapsules and/or nanocapsules (Polymer Assisted Delivery (PAD)
Reservoir System) weight, may be from about 0.1% to about 99%, from
25% to about 95%, from 30 to about 90%, from 45% to about 90%, from
65% to about 90%.
[0246] In one aspect, the amount of total perfume based on total
weight of starch encapsulates and starch agglomerates (Starch
Encapsulated Accord (SEA)) ranges from 0.1% to about 99%, from 25%
to about 95%, from 30 to about 90%, from 45% to about 90%, from 65%
to about 90%. In one aspect, the perfumes and PRM disclosed herein,
including those disclosed in Table 1, and stereoisomers thereof are
suitable for use, in such starch encapsulates and starch
agglomerates. Such perfumes, PRMs and stereoisomers thereof may be
used in combination in such starch encapsulates and starch
agglomerates.
[0247] In one aspect, the amount of total perfume based on total
weight of [cyclodextrin-perfume] complexes (Cyclodextrin (CD))
ranges from 0.1% to about 99%, from 2.5% to about 75%, from 5% to
about 60%, from 5% to about 50%, from 5% to about 25%. In one
aspect, the perfumes and PRM disclosed herein, including those
disclosed in Table 1, and stereoisomers thereof are suitable for
use in such [cyclodextrin-perfume] complexes. Such perfumes, PRMs
and stereoisomers thereof may be used in combination in such
[cyclodextrin-perfume] complexes.
[0248] In one aspect, the amount of total perfume based on total
weight of Polymer Assisted Delivery (PAD) Matrix Systems (including
Silicones) ranges from 0.1% to about 99%, from 2.5% to about 75%,
from 5% to about 60%, from 5% to about 50%, from 5% to about 25%.
In one aspect, the amount of total perfume based on total weight of
a hot melt perfume delivery system/perfume loaded plastic Matrix
System and ranges from 1% to about 99%, from 2.5% to about 75%,
from 5% to about 60%, from 5% to about 50%, from 10% to about 50%.
In one aspect, the perfumes and PRM disclosed herein, including
those disclosed in Table 1, and stereoisomers thereof, are suitable
for use, in such Polymer Assisted Delivery (PAD) Matrix Systems,
including hot melt perfume delivery system/perfume loaded plastic
Matrix Systems. Such perfumes, PRMs and stereoisomers thereof may
be used in combination in such Polymer Assisted Delivery (PAD)
Matrix Systems (including hot melt perfume delivery system/perfume
loaded plastic Matrix Systems).
[0249] In one aspect, the amount of total perfume based on total
weight of Amine Assisted Delivery (AAD) (including Aminosilicones)
ranges from 1% to about 99%, from 2.5% to about 75%, from 5% to
about 60%, from 5% to about 50%, from 5% to about 25%. In one
aspect, the perfumes and PRM disclosed herein, including those
disclosed in Table 1, and stereoisomers thereof are suitable for
use, in such Amine Assisted Delivery (AAD) systems.
[0250] In one aspect, the amount of total perfume based on total
weight of Pro-Perfume (PP) Amine Reaction Product (ARP) system
ranges from 0.1% to about 99%, from about 1% to about 99%, from 5%
to about 90%, from 10% to about 75%, from 20% to about 75%, from
25% to about 60%. In one aspect, the perfumes and PRM disclosed
herein, including those disclosed in Table 1, and stereoisomers
thereof are suitable for use, in such Pro-Perfume (PP) Amine
Reaction Product (ARP) systems.
[0251] The perfume delivery technologies also known as perfume
delivery systems that are disclosed in the present specification
may be used in any combination in any type of consumer product,
cleaning and/or treatment composition, fabric and hard surface
cleaning and/or treatment composition, detergent, and highly
compact detergent.
[0252] In one aspect, an encapsulate comprising a shell and a core,
said shell encapsulating said core and said core comprising a
perfume and/or perfume raw disclosed herein, is disclosed.
[0253] In one aspect, an encapsulate comprising shell and a core,
said core comprising a perfume selected from the group consisting
of the perfumes and PRM disclosed herein, including those in Table
1 A through G, is disclosed.
In one aspect, of the encapsulates provided in the aspects above,
said encapsulates' shells may comprise: [0254] (i) an aminoplast
polymer, in one aspect, said aminoplast polymer comprises a
material selected from the group consisting of a reaction product
of melamine and formaldehyde, a reaction product of urea and
formaldehyde and mixtures thereof, in one aspect, a material
selected from the group consisting of methylol melamine, methylated
methylol melamine, dimethylol urea, methylated dimethylol urea and
mixtures thereof [0255] (ii) a material selected from the group
consisting of a polyacrylate, a polyethylene glycol acrylate, a
polyurethane acrylate, an epoxy acrylate, a polymethacrylate, a
polyethylene glycol methacrylate, a polyurethane methacrylate, an
epoxy methacrylate and mixtures thereof; [0256] (iii) a reaction
product of one or more aromatic alcohols and one or materials
comprising at least one aldehyde moiety in one aspect said aromatic
alcohols may be phenols that comprise two or more hydroxyl groups,
in one aspect, said aromatic alcohols are selected from the group
consisting of brenzcatechin (pyrocatechol), resorcinol,
hydroquinone, 1,4 naphthohydroxyquinone, phloroglucinol,
pyrrogallol, hydroxyhydroquinone and mixtures thereof. In one
aspect, said materials comprising one or more aldehyde moieties
comprise two, three, or four free aldehyde moieties per molecule,
in one aspect, said materials comprising one or more aldehyde
moieties is selected from the group consisting of glyoxal,
gluteraldehyde, succindialdehyde; and/or [0257] (iv) the reaction
product of melamine or a methylenediamine which has the structure
CH.sub.2(NH.sub.2).sub.2, a material comprising one or more
aldehyde moieties, an alkoxy ethanol and an acid, in one aspect,
said material comprising one or more aldehyde moieties is selected
from the group consisting of glyoxal, a
C(4,6)-2,2-dialkoxy-ethanal, in one aspect, 2,2-dimethoxy-ethanal,
or 2,2-diethoxy-ethanal, or mixtures thereof, a glyoxalate and
mixtures thereof.
[0258] In one aspect, a cyclic oligosaccharide complex comprising a
beta-cyclodextrin that is complexed with a perfume and/or perfume
raw disclosed herein, is disclosed.
[0259] A cyclic oligosaccharide complex comprising a
beta-cyclodextrin that is complexed with a perfume selected from
the group consisting of the perfumes and PRM disclosed herein,
including those Table 1 perfumes A through G, is also
disclosed.
Adjunct Ingredients
[0260] For the purposes of the present invention, the non-limiting
list of adjuncts illustrated hereinafter are suitable for use in
the instant compositions and may be desirably incorporated in
certain aspects of the invention, for example to assist or enhance
performance, for treatment of the substrate to be cleaned, or to
modify the aesthetics of the composition as is the case with
perfumes, colorants, dyes or the like. It is understood that such
adjuncts are in addition to the components that are supplied via
Applicants' perfumes and/or perfume systems. The precise nature of
these additional components, and levels of incorporation thereof,
will depend on the physical form of the composition and the nature
of the operation for which it is to be used. Suitable additional
materials include, but are not limited to, bleach activators,
antimicrobial, surfactants, builders, chelating agents, dye
transfer inhibiting agents, dispersants, enzymes, and enzyme
stabilizers, catalytic materials, bleach activators, polymeric
dispersing agents, clay soil removal/anti-redeposition agents,
brighteners, suds suppressors, dyes, structure elasticizing agents,
fabric softeners, carriers, hydrotropes, antiperspirant actives,
processing aids and/or pigments. In addition to the disclosure
below, suitable examples of such other adjuncts and levels of use
are found in U.S. Pat. No. 6,326,348 B1.
[0261] Each adjunct ingredients is not essential to Applicants'
compositions. Thus, certain embodiments of Applicants' compositions
do not contain one or more of the following adjuncts materials:
bleach activators, antimicrobial, surfactants, builders, chelating
agents, dye transfer inhibiting agents, dispersants, enzymes, and
enzyme stabilizers, catalytic metal complexes, polymeric dispersing
agents, clay and soil removal/anti-redeposition agents,
brighteners, suds suppressors, dyes, structure elasticizing agents,
fabric softeners, carriers, hydrotropes, antiperspirant actives,
processing aids and/or pigments. However, when one or more adjuncts
are present, such one or more adjuncts may be present as detailed
below:
[0262] Antimicrobials--Suitable antimicrobials can include, but are
not limited to, metals (e.g., Zn, Cu, Al, Ti, Sn, Bi, and Ag),
metal salts (e.g., zinc carbonate, copper sulfate, and zinc
gluconate), metal pyrithione salts (e.g., ZPT and CuPT), zeolites,
metal zeolites, quaternary ammonium (quat) compounds (e.g., cetyl
pyridinium chloride, and benzylalkonium chloride), quat bound
clays, metal bound clays, and PolyAspirin. Other suitable
antimicrobials can include salicylic acid, polyvinyl amines, coal
tar, sulfur, whitfield's ointment, castellani's paint, aluminum
chloride, gentian violet, octopirox (piroctone olamine), ciclopirox
olamine, undecylenic acid and it's metal salts, potassium
permanganate, selenium sulfide, sodium thiosulfate, propylene
glycol, oil of bitter orange, urea preparations, griseofulvin,
8-Hydroxyquinoline ciloquinol, thiobendazole, thiocarbamates,
haloprogin, polyenes, hydroxypyridone, morpholine, benzylamine,
allylamines (such as terbinafine), tea tree oil, clove leaf oil,
coriander, palmarosa, berberine, thyme red, cinnamon oil, cinnamic
aldehyde, citronellic acid, hinokitol, ichthyol pale, Sensiva
SC-50, Elestab HP-100, azelaic acid, lyticase, iodopropynyl
butylcarbamate (IPBC), Glycols (such as propylene glycol;
dipropylene glycol & hexylene glycol); diols (such as
hexanediol), triclosan, triclocarban, isothiazalinones such as
octyl isothiazalinone and azoles, and combinations thereof.
Suitable antibacterial agents are described in U.S. Pat. No.
6,488,943 and U.S. Patent Application Publication No.
2008/0138441.
[0263] Surfactants--The compositions according to the present
invention can comprise a surfactant or surfactant system wherein
the surfactant can be selected from nonionic and/or anionic and/or
cationic surfactants and/or ampholytic and/or zwitterionic and/or
semi-polar nonionic surfactants. The surfactant is typically
present at a level of from about 0.1%, from about 1%, or even from
about 5% by weight of the cleaning compositions to about 99.9%, to
about 80%, to about 35%, or even to about 30% by weight of the
cleaning compositions.
[0264] Builders--The compositions of the present invention can
comprise one or more detergent builders or builder systems. When
present, the compositions will typically comprise at least about 1%
builder, or from about 5% or 10% to about 80%, 50%, or even 30% by
weight, of said builder. Builders include, but are not limited to,
the alkali metal, ammonium and alkanolammonium salts of
polyphosphates, alkali metal silicates, alkaline earth and alkali
metal carbonates, aluminosilicate builders polycarboxylate
compounds. ether hydroxypolycarboxylates, copolymers of maleic
anhydride with ethylene or vinyl methyl ether,
1,3,5-trihydroxybenzene-2,4,6-trisulphonic acid, and
carboxymethyl-oxysuccinic acid, the various alkali metal, ammonium
and substituted ammonium salts of polyacetic acids such as
ethylenediamine tetraacetic acid and nitrilotriacetic acid, as well
as polycarboxylates such as mellitic acid, succinic acid,
oxydisuccinic acid, polymaleic acid, benzene 1,3,5-tricarboxylic
acid, carboxymethyloxysuccinic acid, and soluble salts thereof.
[0265] Chelating Agents--The compositions herein may also
optionally contain one or more copper, iron and/or manganese
chelating agents. If utilized, chelating agents will generally
comprise from about 0.1% by weight of the compositions herein to
about 15%, or even from about 3.0% to about 15% by weight of the
compositions herein.
[0266] Dye Transfer Inhibiting Agents--The compositions of the
present invention may also include one or more dye transfer
inhibiting agents. Suitable polymeric dye transfer inhibiting
agents include, but are not limited to, polyvinylpyrrolidone
polymers, polyamine N-oxide polymers, copolymers of
N-vinylpyrrolidone and N-vinylimidazole, polyvinyloxazolidones and
polyvinylimidazoles or mixtures thereof. When present in the
compositions herein, the dye transfer inhibiting agents are present
at levels from about 0.0001%, from about 0.01%, from about 0.05% by
weight of the cleaning compositions to about 10%, about 2%, or even
about 1% by weight of the cleaning compositions.
[0267] Dispersants--The compositions of the present invention can
also contain dispersants. Suitable water-soluble organic materials
are the homo- or co-polymeric acids or their salts, in which the
polycarboxylic acid may comprise at least two carboxyl radicals
separated from each other by not more than two carbon atoms.
[0268] Enzymes--The compositions can comprise one or more detergent
enzymes which provide cleaning performance and/or fabric care
benefits. Examples of suitable enzymes include, but are not limited
to, hemicellulases, peroxidases, proteases, cellulases, xylanases,
lipases, phospholipases, esterases, cutinases, pectinases,
keratanases, reductases, oxidases, phenoloxidases, lipoxygenases,
ligninases, pullulanases, tannases, pentosanases, malanases,
.beta.-glucanases, arabinosidases, hyaluronidase, chondroitinase,
laccase, and amylases, or mixtures thereof. A typical combination
is a cocktail of conventional applicable enzymes like protease,
lipase, cutinase and/or cellulase in conjunction with amylase.
[0269] Enzyme Stabilizers--Enzymes for use in compositions, for
example, detergents can be stabilized by various techniques. The
enzymes employed herein can be stabilized by the presence of
water-soluble sources of calcium and/or magnesium ions in the
finished compositions that provide such ions to the enzymes.
[0270] Catalytic Metal Complexes--Applicants' compositions may
include catalytic metal complexes. One type of metal-containing
bleach catalyst is a catalyst system comprising a transition metal
cation of defined bleach catalytic activity, such as copper, iron,
titanium, ruthenium, tungsten, molybdenum, or manganese cations, an
auxiliary metal cation having little or no bleach catalytic
activity, such as zinc or aluminum cations, and a sequestrate
having defined stability constants for the catalytic and auxiliary
metal cations, particularly ethylenediaminetetraacetic acid,
ethylenediaminetetra (methyl-enephosphonic acid) and water-soluble
salts thereof. Such catalysts are disclosed in U.S. Pat. No.
4,430,243.
[0271] If desired, the compositions herein can be catalyzed by
means of a manganese compound. Such compounds and levels of use are
well known in the art and include, for example, the manganese-based
catalysts disclosed in U.S. Pat. No. 5,576,282.
[0272] Cobalt bleach catalysts useful herein are known. Such cobalt
catalysts are readily prepared by known procedures, such as taught
for example in U.S. Pat. No. 5,597,936.
[0273] Compositions herein may also suitably include a transition
metal complex of a macropolycyclic rigid ligand--abbreviated as
"MRL". As a practical matter, and not by way of limitation, the
compositions and cleaning processes herein can be adjusted to
provide on the order of at least one part per hundred million of
the benefit agent MRL species in the aqueous washing medium, and
may provide from about 0.005 ppm to about 25 ppm, from about 0.05
ppm to about 10 ppm, or even from about 0.1 ppm to about 5 ppm, of
the MRL in the wash liquor.
[0274] Suitable transition-metals in the instant transition-metal
bleach catalyst include manganese, iron and chromium. Suitable
MRL's herein are a special type of ultra-rigid ligand that is
cross-bridged such as
5,12-diethyl-1,5,8,12-tetraazabicyclo[6.6.2]hexa-decane.
[0275] Suitable transition metal MRLs are readily prepared by known
procedures, such as taught for example in U.S. Pat. No.
6,225,464.
[0276] The antiperspirant active for use in the anhydrous
antiperspirant compositions of the present invention may include
any compound, composition or other material having antiperspirant
activity. More specifically, the antiperspirant actives may include
astringent metallic salts, especially inorganic and organic salts
of aluminum, zirconium and zinc, as well as mixtures thereof. Even
more specifically, the antiperspirant actives may include
aluminum-containing and/or zirconium-containing salts or materials,
such as, for example, aluminum halides, aluminum chlorohydrate,
aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl
hydroxyhalides, and mixtures thereof.
Method of Use and Use
[0277] Certain of the consumer products disclosed herein can be
used to clean or treat a situs inter alia a surface or fabric.
Typically at least a portion of the situs is contacted with an
embodiment of Applicants' composition, in neat form or diluted in a
liquor, for example, a wash liquor and then the situs may be
optionally washed and/or rinsed. In one aspect, a situs is
optionally washed and/or rinsed, contacted with a particle
according to the present invention or composition comprising said
particle and then optionally washed and/or rinsed. For purposes of
the present invention, washing includes but is not limited to,
scrubbing, and mechanical agitation. The fabric may comprise most
any fabric capable of being laundered or treated in normal consumer
use conditions. Liquors that may comprise the disclosed
compositions may have a pH of from about 3 to about 11.5. Such
compositions are typically employed at concentrations of from about
500 ppm to about 15,000 ppm in solution. When the wash solvent is
water, the water temperature typically ranges from about 5.degree.
C. to about 90.degree. C. and, when the situs comprises a fabric,
the water to fabric ratio is typically from about 1:1 to about
30:1.
[0278] In one aspect, a method of reducing fragrance habituation
comprising optionally washing and/or rinsing a situs, contacting
said situs with any composition disclosed herein that comprises a
perfume and/or perfume raw disclosed herein and mixtures thereof
and optionally washing and/or rinsing and/or drying said situs, is
disclosed.
[0279] In addition to the disclosure above, a method of reducing
fragrance habituation comprising: [0280] a) optionally washing
and/or rinsing a situs; [0281] b) contacting said situs with the
any composition comprising a perfume selected from the group
consisting of Table 1 perfumes A through G and/or a perfume
selected from the group consisting of Table 1 perfumes A through G
and mixtures thereof; and [0282] c) optionally washing and/or
rinsing and/or drying, in one aspect via lined drying and/or
machine drying, said situs is disclosed.
[0283] In one aspect, the use of one or more perfume raw materials
disclosed herein to impart ant-habituation properties to a perfume
and/or consumer product that results in an improved freshness over
time of such perfume and/or consumer is disclosed.
[0284] In one aspect, the use of one or more perfume raw materials
disclosed herein to impart ant-habituation properties to a perfume
and/or consumer product that results in an improved freshness over
time of such perfume and/or consumer, wherein such perfume raw
materials are selected from the group consisting of
a) perfume raw materials comprising a thiol moiety is selected from
the group consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; methanethiol; Ethanethiol;
prop-2-ene-1-thiol; propane-2-thiol; 2-methylpropane-2-thiol;
propane-1-thiol; butane-2-thiol; butane-1-thiol;
2-methylpropane-1-thiol; methyldisulfanylmethane;
2-methylbutane-2-thiol; 3-methylbutane-2-thiol;
3-methylbutane-2-thiol; pentane-2-thiol; pentane-1-thiol;
2-methylbutane-1-thiol; cyclopentanethiol;
3-methyldisulfanylprop-1-ene; methylsulfanyldisulfanylmethane;
1-methyldisulfanylpropane; ethane-1,2-dithiol;
1-(methyldisulfanyl)prop-1-ene; 3-sulfanylbutan-2-one;
ethyldisulfanylethane; hexane-1-thiol; 1-ethyldisulfanylpropane;
thiophene-2-thiol; propane-1,3-dithiol; 3-sulfanylpentan-2-one;
2-propan-2-yldisulfanylpropane; butane-1,4-dithiol; benzenethiol;
ethylsulfanyldisulfanylethane;
3-methylsulfanyldisulfanylprop-1-ene;
1-methylsulfanyldisulfanylpropane; butane-2,3-dithiol;
4-methyl-4-sulfanylpentan-2-one; 3-prop-2-enyldisulfanylprop-1-ene;
1-methoxyhexane-3-thiol; ethyl 2-sulfanylpropanoate;
1-(prop-2-enyldisulfanyl)propane; 1-propyldisulfanylpropane;
1-(4-hydroxy-3-methoxyphenyl)ethanone butane-1,3-dithiol;
1-propyldisulfanylprop-1-ene; 2-methylbenzenethiol;
thiophen-2-ylmethanethiol; 3-sulfanylbutan-2-ol; phenylmethanethiol
pentane-1,5-dithiol; 2-ethylbenzenethiol;
3-prop-2-enylsulfanyldisulfanylprop-1-ene;
methyldisulfanyldisulfanylmethane;
1-propylsulfanyldisulfanylpropane;
2,7,7-trimethylbicyclo[3.1.1]heptane-2-thiol;
2,6-dimethylbenzenethiol; 2-phenylethanethiol; hexane-1,6-dithiol;
2-(methyldisulfanylmethyl)furan; pyridin-2-ylmethanethiol;
2-methoxybenzenethiol;
(7,7-dimethyl-2-bicyclo[3.1.1]heptanyl)methanethiol;
methyldisulfanylbenzene; 1-butyldisulfanylbutane;
(4-methoxyphenyl)methanethiol; 2-sulfanylpropanoic acid; ethyl
2-methyldisulfanylpropanoate;
(2E)-3,7-dimethylocta-2,6-diene-1-thiol;
3,7-dimethylocta-2,6-diene-1-thiol; pyrazin-2-ylmethanethiol;
methyldisulfanylmethylbenzene;
2-methyl-5-(1-sulfanylpropan-2-yl)cyclohexane-1-thiol;
octane-1,8-dithiol; 2-pyrazin-2-ylethanethiol; naphthalene-2-thiol;
2-oxo-3-sulfanylpropanoic acid; 2-thiophen-2-yldisulfanylthiophene;
cyclohexyldisulfanylcyclohexane;
2-(furan-2-ylmethyldisulfanylmethyl)furan; phenyldisulfanylbenzene;
benzyldisulfanylmethylbenzene; 8-Hydroxy-5-quinolinesulfonic acid;
bis(3-methylbutyl) 2-sulfanylbutanedioate; 2-aminoethanesulfonic
acid; 2-phenyl-3H-benzimidazole-5-sulfonic acid;
2-methyl-2-sulfanylpentan-1-ol; and mixtures thereof; b) perfume
raw materials comprising a sulfide moiety is selected from the
group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan;
methylsulfanylmethane; methylsulfanylethane;
3-methylsulfanylprop-1-ene; S-methyl ethanethioate;
ethylsulfanylethane; 1-methylsulfanylpropane; S-ethyl
ethanethioate; 1-methylsulfanylbutane;
2-propan-2-ylsulfanylpropane; bis(methylsulfanyl)methane;
1-ethylsulfanylpropane; thiolane; 1-propylsulfanylpropane;
1-ethylsulfanylbutane; S-ethyl propanethioate; S-methyl
butanethioate; S-methyl 3-methylbutanethioate;
3-methylsulfanylpropanal; 3-prop-2-enylsulfanylprop-1-ene; methyl
2-methylsulfanylacetate; S-prop-2-enyl propanethioate;
1-methylsulfanylbutan-2-one; 4-methylsulfanylbutan-2-one;
3-methylsulfanylpropan-1-am; 2,4,6-trimethyl-1,3,5-trithiane;
3-methylsulfanylbutanal; 2-methyl-1,3-thiazolidine;
2-methyl-4,5-dihydro-1,3-thiazole; ethyl 2-methylsulfanylacetate;
methyl 3-methylsulfanylpropanoate; S-propan-2-yl
3-methylbutanethioate; 4-methyl-4-methylsulfanylpentan-2-one;
2-methyl-1,3-dithiolane; methyl 2-methylsulfanylbutanoate; S-methyl
furan-2-carbothioate; S-propan-2-yl 3-methylbut-2-enethioate;
thiolan-3-one; 3,5-diethyl-1,2,4-trithiolane;
methylsulfanylmethylbenzene; 3-methylsulfanylpropan-1-ol;
2-(propan-2-ylsulfanylmethyl)furan; 2-methyl-5-methylsulfanylfuran;
S-(furan-2-ylmethyl) methanethioate; 1,2,4-trithiolane;
2-methylthiolan-3-one; 4-methylsulfanylbutan-1-ol; S-butan-2-yl
3-methylbutanethioate; S-butan-2-yl 3-methylbut-2-enethioate;
S-(furan-2-ylmethyl)ethanethioate; 2-propyl-1,3-thiazolidine;
3-methyl-1,1-bis(methylsulfanyl)butane; 3-ethylsulfanylpropan-1-ol;
S-methyl benzenecarbothioate; 3,5-dimethyl-1,2,4-trithiolane;
S-butan-2-yl 2-methylbutanethioate; methylsulfanylbenzene;
1-pentylsulfanylpentane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-methyl-4-propyl-1,3-oxathiane; ethyl
2-methyl-2-methylsulfanylpropanoate; S-(furan-2-ylmethyl)
propanethioate; 4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
3-methyl-1,2,4-trithiane; methylsulfanylmethyl hexanoate;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone; 3-methylsulfanylpropanoic
acid; 5-methylsulfanyl-2-(methylsulfanylmethyl)pent-2-enal;
4,5-dimethyl-2-(2-methylpropyl)-2,5-dihydro-1,3-thiazole;
3-methylsulfanylhexan-1-ol; 2-methyl-4,5-dihydrofuran-3-thiol
acetate; 4-(3-oxobutylsulfanyl)butan-2-one;
3-methylsulfanylbutanoic acid; 2-methylsulfanylpyrazine;
2-methyl-3-methylsulfanylpyrazine;
2-(furan-2-ylmethylsulfanylmethyl)furan;
2-(methylsulfanylmethyl)pyrazine;
3,5-di(propan-2-yl)-1,2,4-trithiolane; 2-methylsulfanylphenol;
2-methyl-3-methylsulfanylpyrazine; ethyl
3-(furan-2-ylmethylsulfanyl)propanoate;
2,2,4,4,6,6-hexamethyl-1,3,5-trithiane;
2-methyl-5,7-dihydrothieno[3,4-d]pyrimidine;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
2',3a-dimethylspiro[6,6a-dihydro-5H-[1,3]dithiolo[4,5-b]furan-2,3'-oxolan-
e]; 2,5-dimethyl-1,4-dithiane-2,5-diol; Methyl 2-thiofuroate and
mixtures thereof; c) perfume raw materials comprising a thiazole
moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
2,4,5-Trimethylthiazole; 2-isopropyl-4-methylthiazole;
4-vinyl-5-methylthiazole; 2,4-Dimethyl-5-acetylthiazole
1,3-thiazole; 4-methyl-1,3-thiazole; 2,4-dimethyl-1,3-thiazole;
4,5-dimethyl-1,3-thiazole; 2,5-dimethyl-1,3-thiazole;
5-ethenyl-4-methyl-1,3-thiazole; 2-ethyl-4-methyl-1,3-thiazole;
4-ethyl-2-methyl-1,3-thiazole; 2-propyl-1,3-thiazole;
2,4,5-trimethyl-1,3-thiazole; 2-ethyl-1,3-thiazole;
2-ethoxy-1,3-thiazole; 2-butan-2-yl-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole; 2-ethyl-4,5-dimethyl-1,3-thiazole;
1,3-benzothiazole; 2,5-diethyl-4-methyl-1,3-thiazole;
1-(1,3-thiazol-2-yl)propan-1-one;
4,5-dimethyl-2-(2-methylpropyl)-1,3-thiazole;
2-methyl-1,3-benzothiazole;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
4-methyl-2-propan-2-yl-1,3-thiazole; and mixtures thereof; d) said
perfume raw material comprising a pyrazine moiety is selected from
the group consisting of 2-methoxy-3-(2-methylpropyl)pyrazine;
2,3-dimethylpyrazine; 1-pyrazin-2-ylethanone;
2-methyl-3-methylsulfanylpyrazine; Pyrazine; 2-methylpyrazine;
2-ethenylpyrazine; 2-ethylpyrazine; 2,6-dimethylpyrazine;
2,5-dimethylpyrazine; 2-prop-1-en-2-ylpyrazine;
2-propan-2-ylpyrazine; 2-methoxypyrazine;
2-ethenyl-5-methylpyrazine; 2-ethyl-5-methylpyrazine;
2-Ethyl-6-methylpyrazine; 2-Ethyl-3-Methyl-Pyrazine;
2-propylpyrazine; 2,3,5-trimethylpyrazine; 2-tert-butylpyrazine;
pyrazin-2-amine; 2-(2-methylpropyl)pyrazine;
2-methyl-5-propan-2-ylpyrazine; 2-(methoxymethyl)pyrazine;
2,3-diethylpyrazine; 2-ethyl-3,(5 OR 6)-dimethylpyrazine;
2-ethyl-3,5-dimethylpyrazine; 3-ethyl-2,5-dimethylpyrazine;
3-ethyl-2,5-dimethylpyrazine; 2-ethyl-3,5-dimethylpyrazine;
2-methyl-3-propylpyrazine; 2,3,5,6-tetramethylpyrazine;
7-methyl-6,7-dihydro-5H-cyclopenta[b]pyrazine;
2-methylsulfanylpyrazine; 2-methyl-3-methylsulfanylpyrazine;
2-ethoxy-3-ethylpyrazine; 2-Isobutyl-3-methylpyrazine;
pyrazin-2-ylmethanethiol; 3,5-dimethyl-2-propylpyrazine;
2-ethyl-3-methoxypyrazine; 2-ethoxy-3-methylpyrazine;
2-ethyl-5-methoxypyrazine; 5,6,7,8-tetrahydroquinoxaline;
2-ethoxy-3-propan-2-ylpyrazine; 2-(methylsulfanylmethyl)pyrazine;
3,5-dimethyl-2-(2-methylpropyl)pyrazine;
2,3-diethyl-5-methylpyrazine; 3,5-Diethyl-2-methylpyrazine;
2,5-dimethyl-3-(2-methylpropyl)pyrazine;
2-methyl-6-propoxypyrazine; 2-(2-methylpropoxy)pyrazine;
1-(3-methylpyrazin-2-yl)ethanone;
2-methyl-3-methylsulfanylpyrazine; 2-methoxy-3-propan-2-ylpyrazine;
quinoxaline; 3-butyl-2,5-dimethylpyrazine;
2-butyl-3,5-dimethylpyrazine; 2-pyrazin-2-ylethanethiol;
1-(3-ethylpyrazin-2-yl)ethanone;
1-(3,5-dimethylpyrazin-2-yl)ethanone;
2-butan-2-yl-3-methoxypyrazine; 2-methylquinoxaline;
5-Methylquinoxaline; 2-methoxy-3-(4-methylpentyl)pyrazine;
2,3-dimethylquinoxaline; 2-(cyclohexylmethyl)pyrazine;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine and mixtures
thereof; e) perfume raw materials comprising a nitrile moiety is
selected from the group consisting of 3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
f) perfume raw materials comprising a indole moiety is selected
from the group consisting of 1H-indole, 3-methyl-1H-indole; and
mixtures thereof; g) perfume raw materials comprising a oxathiane
moiety is selected from the group consisting of
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane,
2-methyl-4-propyl-1,3-oxathiane, 2-pentyl-4-propyl-1,3-oxathiane;
and mixtures thereof; h) perfume raw materials comprising a oxime
moiety is selected from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
N-(5-methylheptan-3-ylidene)hydroxylamine, and mixtures thereof; i)
perfume raw materials comprising a amine moiety is selected from
the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine; 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof;
[0285] In one aspect, said perfume raw materials comprise at least
one sulfur, oxygen and nitrogen atom, said perfume raw material
being selected from the group consisting of
2-(4-methyl-1,3-thiazol-5-yl)ethanol; 1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
2-[(furan-2-ylmethyl)sulfanyl]-5-methylpyrazine;
2,4-Dimethyl-5-acetylthiazole; 2-ethoxy-1,3-thiazole;
5-methoxy-2-methyl-1,3-thiazole;
1-(4,5-dihydro-1,3-thiazol-2-yl)ethanone;
1-(1,3-thiazol-2-yl)propan-1-one;
1-(2,4-dimethyl-1,3-thiazol-5-yl)ethanone;
2-amino-4-methylsulfanylbutanoic acid;
(2S)-2-amino-4-methylsulfanylbutanoic acid;
8-Hydroxy-5-quinolinesulfonic acid; 2-aminoethanesulfonic acid;
2-phenyl-3H-benzimidazole-5-sulfonic acid; and mixtures
thereof;
[0286] In one aspect:
a) said perfume raw materials comprising a thiol moiety is selected
from the group consisting of 5-methyl-5-sulfanylhexan-3-one;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one;
4,7,7-trimethyl-6-thiabicyclo[3.2.1]octane;
4-methoxy-2-methylbutane-2-thiol; and mixtures thereof; b) said
perfume raw materials comprising a sulfide moiety is selected from
the group consisting of 1-butylsulfanylbutane; ethyl
3-methylsulfanylpropanoate; 2-(methylsulfanylmethyl)furan; and
mixtures thereof; c) said perfume raw materials comprising a
thiazole moiety is selected from the group consisting of
2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
4-methyl-2-propan-2-yl-1,3-thiazole;
4-methyl-2-propan-2-yl-1,3-thiazole; 1-(1,3-thiazol-2-yl)ethanone;
and mixtures thereof; d) said perfume raw materials comprising a
pyrazine moiety is selected from the group consisting of
2-methoxy-3-(2-methylpropyl)pyrazine; 2,3-dimethylpyrazine;
1-pyrazin-2-ylethanone; 2-methyl-3-methylsulfanylpyrazine; and
mixtures thereof; e) said perfume raw materials comprising a
nitrile moiety is selected from the group consisting of
3,7-dimethyloct-6-enenitrile,
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; and mixtures thereof;
f) said perfume raw materials comprising a indole moiety is
selected from the group consisting of 1H-indole. g) said perfume
raw materials comprising a oxathiane moiety is selected from the
group consisting of (2R,4S)-2-methyl-4-propyl-1,3-oxathiane. h)
said perfume raw materials comprising a oxime moiety is selected
from the group consisting of
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine.
i) said perfume raw materials comprising a amine moiety is selected
from the group consisting of methyl 2-aminobenzoate,
pentane-1,5-diamine, 6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane;
and mixtures thereof; j) said perfume raw materials comprising
oxygen, sulfur, and nitrogen is selected from the group consisting
of 2-(4-methyl-1,3-thiazol-5-yl)ethanol,
1-(1,3-thiazol-2-yl)ethanone;
6-methyl-7-Oxa-1-thia-4-azaspiro[4.4]nonane; and mixtures
thereof;
[0287] In one aspect, said perfume raw material comprises perfume
raw materials selected from the group consisting of:
a) 1-butylsulfanylbutane; (2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
and 4-methoxy-2-methylbutane-2-thiol; b)
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and 7-hydroxy-3,7-dimethyloctanal;
3-(4-ethylphenyl)-2,2-dimethylpropanenitrile; c)
2-(4-methyl-1,3-thiazol-5-yl)ethanol;
7-Oxa-1-thia-4-azaspiro[4.4]nonane; and 6-methyl-,
1-(1,3-thiazol-2-yl)ethanone; d)
2-methoxy-3-(2-methylpropyl)pyrazine; 1-pyrazin-2-ylethanone; and
2,3-dimethylpyrazine; e) 2-(methylsulfanylmethyl)furan; ethyl
3-methylsulfanylpropanoate; and 1-butylsulfanylbutane; f)
5-methyl-5-sulfanylhexan-3-one;
5-methyl-2-(2-sulfanylpropan-2-yl)cyclohexan-1-one; and
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; g)
2-methoxy-3-(2-methylpropyl)pyrazine; 3,7-dimethyloct-6-enenitrile;
and methyl 2-aminobenzoate; h) 2-(2-methylpropyl)-1,3-thiazole;
2-(4-methyl-1,3-thiazol-5-yl)ethanol; and
4-methyl-2-propan-2-yl-1,3-thiazole; i)
(2R,4S)-2-methyl-4-propyl-1,3-oxathiane;
2-(4-methyl-1-cyclohex-3-enyl)propane-2-thiol; and
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine;
and j) mixtures thereof; is disclosed.
[0288] In one aspect, a method to enhance the fragrance profile of
a composition, preferably improve the longevity of an aroma,
preferably a floral aroma, of a composition, comprising bringing
into contact or mixing at least one non-odorous fragrance modulator
with at least one low volatile fragrance material according to a
composition as defined herein previously is disclosed. In one
aspect, said floral aroma is selected from the group consisting of
a lavender-type note, a rose-type note, a lily of the valley type
note, a muguet type note, a magnolia type note, a cyclamen type
note, a hyacinth type note, a lilac type note, and combinations
thereof.
[0289] In one aspect, a method for producing a consumer product
comprising bringing into contact or mixing into the product an
organoleptically active quantity of a perfume composition disclosed
herein, said perfume composition comprising a fragrance modulator,
is disclosed.
[0290] In one aspect, a method of modifying or enhancing the odour
properties of a body surface, comprising contacting or treating the
body surface with a perfume composition disclosed herein, said
perfume composition comprising a fragrance modulator, is
disclosed.
Test Methods
[0291] The Degree of Habituation to a perfume, PRM or product
comprising such materials, is determined via human panel testing
with daily exposures to the scent over a four week period, and is
calculated at both the week two and week four time points, relative
to the initial baseline time point.
[0292] For each exposure panel test, more than 15 panelists are
recruited, then exposed to the test scent in a manner, frequency,
and concentration indicated by the intended product end use, but
including at least one exposure per day every day for four
consecutive weeks. The perfume exposure must be sufficient that the
panelists can detect the perfume of interest being delivered from
the product or perfume delivery system contained within the
product. The criteria for recruitment onto the exposure panel
requires that panelists be typical consumers of the product in
question, who agree to use the scent being tested, are non-smokers,
and free of nasal congestion and allergies. The degree of
habituation is calculated and reported as the percent change in the
Odor Detection Threshold (ODT) value at week 2 and at week 4,
versus the initial baseline ODT value. Since the degree of
habituation is a relative measure, it accommodates the variation in
absolute ODT values which can arise between different testing
laboratories.
[0293] Raw materials and finished products comprising them may be
used together in conjunction in order to determine the degree of
habituation. For example, daily exposures to the panelists may
involve the use of a finished product while the ODT test
measurements may involve the use of the respective neat perfume or
PRM. The conditions selected for use in either the daily exposures
or in the ODT testing must be applied uniformly across all
panelists, and remain unchanged for the entirety of the four week
testing period. When the test perfume materials are available in
their simple forms i.e., PRM, neat perfume, or fine fragrance,
unincorporated into complex products or delivery systems, then the
ODT test is to be conducted with these simple forms via an
olfactometer, as this is the preferred method. When these simple
forms of the test perfume materials are inaccessible for testing,
then the ODT test may be conducted with finished products or
complex formulations comprising the test perfume materials.
Presentation devices other than an olfactometer may be required
when conducting the ODT testing on finished products or complex
formulations, and may include devices such as sniff cups, headspace
chambers and capped bottles, as allowed for in the test method ASTM
E679-04 described below.
[0294] The ODT value for each panelist is determined at each of
three time points the during four week daily exposure period,
namely; at initial baseline, at two weeks, and at four weeks. The
ODT values are always to be determined in accordance with test
method ASTM E679-04 (Standard Practice for Determination of Odor
and Taste Thresholds by a Forced-Choice Ascending Concentration
Series of Limits) as reapproved in 2011 except, the following
replaces the protocol of such test method's Sub-articles 4.4, 8.2
and 8.3.
[0295] Sub-article 4.4, Individual best-estimate values of the
threshold are derived from the pattern of correct/incorrect
responses produced separately by each panelist. The group average
ODT value at a given time point is derived by fitting the entire
data set from all panelists at that time point to a Log Logistic
Regression Model.
[0296] Sub-article 8.2, If the concentration range has been
correctly selected, it is not necessary that all panelists judge
correctly within the range of concentration steps provided. Thus,
the representation of the panelists' judgments as in 8.1 need not
terminate with two or more consecutive plusses (+).
[0297] Sub-article 8.3, Since there is a finite probability that a
correct answer will occur by chance alone, it is important that a
panelist repeat the test three times. Panelists who fail the test
at the highest concentration, are deemed anosmic to the test
material and their response is removed from the data set.
[0298] Additionally, the following selections are made in
accordance with the test method's sub-articles 1.3, 1.4, 1.6, 1.7,
and 4.1, and specified here as per sub-article 9.3.
[0299] Sub-article 1.3, The threshold is characterized as being a)
only detection (awareness) that a very small amount of added
substance is present but not necessarily recognizable.
[0300] Sub-article 1.4, When the preferred method is being
conducted, namely using a simple perfume form presented via
olfactometer, then the presentation medium can be an air, pure
nitrogen, or a mixture of the two. When testing finished or complex
products, alternative presentation media may be used, such as
air.
[0301] Sub-article 1.6, When the preferred method is being
conducted, namely using a simple perfume form presented via
olfactometer, then the physical method of presentation is at a rate
of 40 L/min.
[0302] When testing finished or complex products, alternative
presentation devices may be used, including but not limited to
sniff cups, headspace chambers or capped bottles.
[0303] Sub-article 1.7, Presentation is made to a panel of greater
than 15 panelists, who are participating in the daily exposure
panel.
[0304] Sub-article 4.1, Eight scale steps are used, with each step
having an individual predetermined dilution factor suitable for the
stimuli being tested, at a temperature of 35.degree. C. PRM or neat
perfume stimuli are typically introduced to the olfactometer system
in the neat form via a pump syringe. Sometimes a dilution of the
stimuli with ethanol is needed.
[0305] The group average ODT values from the three time points are
used to calculate the degree of habituation. The degree of
habituation is reported for 2 specific time points, as the percent
change in group average ODT at one time point, relative to the
group average ODT at the initial baseline time point. The degree of
habituation is determined at the time points of: 2 weeks and 4
weeks, of the four week daily exposure period, using the following
formula:
Degree of Habituation (percent change in ODT) at Time X=((Group
Average ODT.sub.(Time X)-Group Average ODT.sub.(Baseline))/Group
Average ODT.sub.(Baseline)).times.100
where Time X is either 2 weeks, or 4 weeks, of repeated daily
exposure.
Anti-Habituation Index
[0306] A perfume is considered to have an anti-habituation index
of:
[0307] For a two week test [0308] Zero (0) when the Degree of
Habituation after 2 weeks of exposure to said perfume is from about
150% to 25% [0309] One (1) when the Degree of Habituation after 2
weeks of exposure to said perfume is less than 25% but greater than
10%; [0310] Two (2) when the Degree of Habituation after 2 weeks of
exposure to said perfume is from 10% to 0%; or [0311] Three (3)
when the Degree of Habituation after 2 weeks of exposure to said
perfume is less than 0% to about -25%. [0312] Four (4) when the
Degree of Habituation after 2 weeks of exposure to said perfume is
less than -25% to about -500%
[0313] For a four week test [0314] Zero (0) when the Degree of
Habituation after 4 weeks of exposure to said perfume is from about
150% to 25% [0315] One (1) when the Degree of Habituation after 4
weeks of exposure to said perfume is less than 25% but greater than
10%; [0316] Two (2) when the Degree of Habituation after 4 weeks of
exposure to said perfume is from 10% to 0%; or [0317] Three (3)
when the Degree of Habituation after 4 weeks of exposure to said
perfume is less than 0% to about -25%. [0318] Four (4) when the
Degree of Habituation after 4 weeks of exposure to said perfume is
less than -25% to about -500%
EXAMPLES
[0319] While particular embodiments of the present invention have
been illustrated and described, it would be obvious to those
skilled in the art that various other changes and modifications can
be made without departing from the spirit and scope of the
invention. It is therefore intended to cover in the appended claims
all such changes and modifications that are within the scope of
this invention.
Example 1
Example Anhydrous Stick Compositions that Resist Habituation,
Excluding Formula IV
TABLE-US-00002 [0320] Formula Formula Formula Formula Formula I II
III IV Formula V VI Invisible Invisible Invisible Soft Soft Soft
Solid Solid Solid Solid Solid Solid Aluminum 24 24 24 26.5 26.5
26.5 Zirconium Trichlorohydrex Glycine Powder Cyclopentasiloxane
Q.S Q.S. Q.S. Q.S. Q.S. Q.S. Dimethicone -- -- -- 5 5 5 CO-1897
Stearyl 14 14 14 -- -- -- Alcohol NF Hydrogenated 3.85 3.85 3.85 --
-- -- Castor Oil MP80 Deodorized Behenyl Alcohol 0.2 0.2 0.2 -- --
-- Tribehenin -- -- -- 4.5 4.5 4.5 C 18-36 acid -- -- -- 1.125
1.125 1.125 triglyceride C12-15 Alkyl 9.5 9.5 5 -- -- -- Benzoate
PPG-14 Butyl 6.5 6.5 -- 0.5 0.5 0.5 Ether Phenyl 3 -- 3 -- -- --
Trimethicone White Petrolatum 3 -- -- 3 3 3 Mineral Oil 1.0 1.0 1.0
-- -- -- Typical Perfume 0.5 -- -- 0.9 -- -- Marketed -- -- -- --
-- 0.75 Perfume Perfume Table 1 0.5 1.1 0.9 -- 1.0 --
Beta-Cyclodextrin -- 3.0 -- -- -- 3.0 complexed with perfume Table
1 Talc Imperial 250 3.0 3.0 3.0 -- -- -- USP Polyacrylate -- -- 1.9
-- -- -- Microcapsule loaded with perfume Table 1 QS - indicates
that this material is used to bring the total to 100%.
[0321] With the exception of Formula IV, the formulations defined
above contain perfume from table 1 at various levels, optionally
using various perfume delivery systems. Formula III contains
Perfume from Table 1 contained in a polyacrylate microcapsule, as
described above in Polymer Assisted Deliver, Reservoir Systems.
Formula VI contained perfume from table 1, as described above in
Cyclodextrin Delivery Systems.
[0322] Test subjects were recruited for the following study, based
on their acceptance of the scent of the products in formulas IV, V,
and VI above. Approximately 20 test subjects per usage group were
recruited for the study. The test subjects placed in the study were
assessed for their baseline threshold intensity according to the
Odor Detection Threshold (ODT) method defined above for the perfume
of interest that was in the product. Test subjects were placed in
three study groups with an antiperspirant/deodorant according to
formulas IV, V, and VI and instructed to apply 2 clicks per
underarm (approximately 0.4 g per underarm) throughout the four
week study period, using no other underarm products throughout the
duration of the study. Their Odor Detection Threshold (ODT) was
measured again after 2 weeks of usage, and again after 4 weeks of
usage. The average Odor Detection Threshold was calculated for each
usage group. Results are shown below.
[0323] The results indicate that the Odor Detection Threshold
increases significantly above baseline (test subjects are less
sensitive) for the usage group using Formula IV (comparative
perfume) after 4 weeks of usage, indicating habituation. The
surprising result is that the Odor Detection Threshold remains
below baseline for each usage group using formula V and formula VI
that contain the perfume from table 1, indicating that they did not
become habituated to the scent of the product over time. Therefore,
the perfume used in formula V and VI is has an anti-habituation
index of 4 and 3 respectively when tested in a two week test and an
anti-habituation index of 4 and 4 respectively when tested in a
four week test.
TABLE-US-00003 Degree of Habituation (% change in group average
ODT) Results: % Change % Change Type of Perfume Run in ODT in ODT
Product Used in the ODT test at Week 2 at Week 4 Formula IV from
Comparative Perfume 41% 634% Example 1 Formula V from Perfume from
Table 1 -86% -29% Example 1 Formula VI from Perfume from Table 1
-24% -91% Example 1
Example 2
Anhydrous Stick Compositions that Resist Habituation
TABLE-US-00004 [0324] TABLE 2 Base Perfume Formulation PD
Ingredient Percent CAS# 2 6 Nonadienol 10% In DPG 0.20% Allyl Amyl
Glycolate 0.10% 67634-00-8 Allyl Cyclohexane Propionate 0.50%
2705-87-5 Allyl Heptoate 1.00% 142-19-8 Ambrettolide 0.50%
28645-51-4 Anisic Aldehyde 0.10% 123-11-5 Benzaldehyde 0.05%
100-52-7 Benzoin Siam Resinoid 50% Mpg Ref A 0.20% 9000-72-0 Benzyl
Acetate 3.00% 140-11-4 Benzyl Salicylate 5.00% 118-58-1 Beta Gamma
Hexenol 0.20% 928-96-1 Cashmeran 0.20% 33704-61-9 Cinnamic Alcohol
0.10% 104-54-1 Cis 3 Hexenyl Acetate 0.30% 3681-71-8 Cis-3-Hexenyl
Salicylate 1.00% 65405-77-8 Cis-6-Nonen-1-OL FCC 0.05% 35854-86-5
Citronellol 0.30% 106-22-9 Citronellyl Acetate 0.10% 150-84-5
Citronellyl Oxyacetaldehyde 0.04% 7492-67-3 Cyclo Galbanate 0.10%
68901-15-5 Cymal 4.00% 103-95-7 Delta Damascone 0.20% 57378-68-4
Delta Muscenone 962191 0.10% 63314-79-4 Dihydro Myrcenol 2.00%
18479-58-8 Dimethyl Benzyl Carbinyl Acetate 0.50% 151-05-3 Ethyl 2
Methyl Pentanoate 0.30% 39255-32-8 Ethyl Acetoacetate 0.50%
141-97-9 Ethyl Maltol 0.40% 4940-11-8 Ethyl-2-Methyl Butyrate 0.10%
7452-79-1 Ethylene Brassylate 7.00% 105-95-3 Floralozone 0.50%
67634-15-5 Gamma Decalactone 0.50% 706-14-9 Geranyl Acetate 0.20%
105-87-3 Helional 1.00% 1205-17-0 Heliotropin 0.10% 120-57-0
Hexamethylindanopyran 10.00% 1222-05-5 Hexyl Acetate 0.50% 142-92-7
Hexyl Cinnamic Aldehyde 7.00% 101-86-0 Hydroxycitronellal 3.00%
107-75-5 Indolene 0.20% 68908-82-7 Ionone Gamma Methyl 5.00%
127-51-5 Iso E Super Or Wood 10.00% 54464-57-2 Iso Eugenol 0.05%
97-54-1 Jasmolactone 0.10% 32764-98-0 Laevo Trisandol 2.00%
28219-61-6 Liffarome 0.40% 67633-96-9 Ligustral Or Triplal 0.20%
68039-49-6 Linalool 5.00% 78-70-6 Linalyl Acetate 3.00% 115-95-7
Lyral 2.00% 31906-04-4 Melonal 0.20% 106-72-9 Methyl Dihydro
Jasmonate 10.00% 24851-98-7 Methyl Pamplemousse 0.30% 67674-46-8
Methyl Phenyl Carbinyl Acetate 0.40% 93-92-5 Methyl-2-Nonenoate
0.10% 111-79-5 Nerolidol 0.50% 7212-44-4 Oil Lemon Brazilcp Select
Fcc Enh 1.00% 8008-56-8 15130 Orivone 0.20% 16587-71-6 Para Hydroxy
Phenyl Butanone 1.00% 5471-51-2 Phenyl Ethyl Alcohol 0.50% 60-12-8
Phenyl Ethyl Phenyl Acetate 0.05% 102-20-5 Pino Acetaldehyde 0.05%
33885-51-7 Polysantol 0.20% 107898-54-4 Precyclemone B 0.30%
52475-86-2 Prenyl Acetate 0.20% 1191-16-8 Prunella 0.10% Synambran
R 50% In IPM* 0.20% Undecalactone 2.00% 104-67-6 Undecavertol 0.50%
81782-77-6 Undecylenic Aldehyde 0.01% 112-44-7 Vanillin 0.30%
121-33-5 Verdox 3.00% 88-41-5 *Supplied by Symrise GmbH, with
offices located at Muhlenfeldstrasse 1, Holzminden, 37603,
Germany
TABLE-US-00005 TABLE 3 Control Perfume Formulation PD with
additional perfume raw materials Perfume Perfume Perfume Perfume
2.A 2.B 2.C 2.D Base Control Perfume 99.9987% 98.99999% 99.94%
93.5% Formulation PD from Table 2 5-Mercapto-5-Methyl-3- 0.001%
hexanone P-Mentha-8-Thiol-3-One 0.00025% 1-para-menthene-8-thiol
0.00005% 2-methoxy-3-(2- 0.00001% methylpropyl)pyrazine
3,7-dimethyloct-6-enenitrile 0.5% methyl 2-aminobenzoate 0.5%
2-(4-methyl-1,3-thiazol-5- 0.05% yl)ethanol 2-(2-methylpropyl)-1,3-
0.005% thiazol 4-methyl-2-propan-2-yl- 0.005% 1,3-thiazole
(1R,2S,5R)-5-methyl-2- 5.0% propan-2-ylcyclohexan-1-ol
[(1R,2S,5R)-5-methyl-2- 1.0% propan-2-ylcyclohexyl] acetate
(2R,5R)-5-methyl-2- 0.5% (propan-2-yl)cyclohexanone
TABLE-US-00006 TABLE 4 Soft Solid Antiperspirant Compositions
Formula Formula Formula Formula VII Soft VIII Soft IX Soft Formula
X XI Soft Solid Solid Solid Soft Solid Solid Aluminum 26.5 26.5
26.5 26.5 26.5 Zirconium Trichlorohydrex Glycine Powder
Cyclopentasiloxane Q.S. Q.S. Q.S. Q.S. Q.S. Dimethicone 5 5 5 5 5
Tribehenin 4.5 4.5 4.5 4.5 4.5 C 18-36 acid 1.125 1.125 1.125 1.125
1.125 triglyceride PPG-14 Butyl Ether 0.5 0.5 0.5 0.5 0.5 White
Petrolatum 3 3 3 3 3 Base Control 0.8 -- -- -- -- Perfume
Formulation Perfume 2.A -- 0.8 -- -- -- Perfume 2.B -- -- 0.8 -- --
Perfume 2.C -- -- -- 0.8 -- Perfume 2.D -- -- -- -- 0.8 QS -
indicates that this material is used to bring the total to
100%.
[0325] The formulations defined above various perfume formulations.
Formula VII contains a base control perfume formulation PD.
Formulas VIII, IX, X, and XI each contain additional components.
More specifically, formula VIII containing Perfume 2.A includes a
three component perfume accord composed of perfume raw materials
containing a thiol moiety. Formula IX containing Perfume 2.B
includes a three component perfume accord composed of perfume raw
materials containing pyrazine, nitrile and amine moieties. Formula
X containing Perfume 2.C includes a three component perfume accord
composed of perfume raw materials containing a thiazole moiety.
Formula XI containing Perfume 2.D includes a three component
perfume accord composed of perfume raw materials consisting of
menthol and menthol derivatives.
[0326] Approximately 20 test subjects per usage group were
recruited for the study. The test subjects placed in the study were
assessed for their baseline threshold intensity according to the
Odor Detection Threshold (ODT) method defined above for the perfume
of interest that was in the product. Test subjects were placed in
five study groups with an antiperspirant/deodorant according to
formulas VII, VIII, IX, X, and XI and instructed to apply 2 clicks
per underarm (approximately 0.4 g per underarm) throughout the four
week study period, using no other underarm products throughout the
duration of the study. Their Odor Detection Threshold (ODT) was
measured again after 2 weeks of usage, and again after 4 weeks of
usage. The average Odor Detection Threshold was calculated for each
usage group. Results are shown below.
[0327] The results indicate that the Odor Detection Threshold
remains unchanged for the usage group using Formula VII
(comparative perfume) after 4 weeks of usage. The Odor Detection
Threshold increases significantly above baseline (test subjects are
less sensitive) for the usage group using Formula XI (perfume
containing menthol and menthol derivatives) after 4 weeks of usage,
indicating habituation. One surprising result is that the base
perfume's (Formula VII) anti-habituation index of two (2) from the
two week test moved, when antihabituation materials were added
(formulations VIII, IX and X) to an anti-habituation indices for
such formulas of, 4, 4 and 3 respectively under the two week test
when the additional perfume raw materials(s) as specified in
Perfume 2.A, Perfume 2.B and Perfume 2.C are added. Another
surprising result is that the base perfume's (Formula VII)
anti-habituation index of three (3) from the four week test moved,
when antihabituation materials were added (formulations VIII, IX
and X) to an anti-habituation indices for such formulas of, 4, 4
and 4 respectively under the four week test when the additional
perfume raw materials(s) as specified in Perfume 2.A, Perfume 2.B
and Perfume 2.C are added. Such materials were a thiol accord,
pyrazine-nitrile-amine accord, and thiazole accord.
TABLE-US-00007 TABLE 5 Degree of Habituation (% change in group
average ODT) Results: % Change % Change Product Type of Perfume Run
in the ODT in ODT at in ODT at Used Test Week 2 Week 4 Formula VII
Base Perfume Formulation PD 2% -2% Formula VIII Perfume 2.A - -86%
-93% Base Control Perfume Formulation PD comprising Thiol Accord
Formula IX Perfume 2.B - -94% -90% Base Control Perfume Formulation
PD comprising pyrazine-nitrile- amine Accord Formula X Perfume 2.C
-6% -62% Base Control Perfume Formulation PD comprising Thiazole
Accord Formula XI Perfume 2.D 96% 1052% Base Control Perfume
Formulation PD comprising menthol and menthol derivative Accord
[0328] The above formulations VII, VIII, IX, X, and XI were rated
by consumers in a usage test. 10 independent test groups of
approximately 20 panelists were instructed to use the product as
they normally would. 5 of the test groups, each using one of the
formulas VII, VIII, IX, X, and XI were instructed to use the
product for a single day, and rate their overall opinion of the
product after using the product based on a 5 point scale.
(100=Excellent, 75=Very Good, 50=Good, 25=Fair, 0=Poor).
Separately, the other 5 test groups, each using one of the formulas
VII, VIII, IX, X, and XI were instructed to use the product for a
four week period, and rate their overall opinion of the product
based on the same 5 point scale defined above. Results indicate
that formulas are rated parity after a single day usage, but the
resistance to habituation shown in table 5 yields an improved usage
rating, only after a four week period.
TABLE-US-00008 TABLE 6 Formula Formula Formula VII VIII IX Formula
X Formula XI Overall 64 57 60 65 66 Rating Single Day Use Overall
66 69 75 80 70 Rating 4 Week Use Delta of +2 +12 +15 +15 +4 single
day vs. 4 week ratings
Example 3
Anhydrous Stick Compositions that Resist Habituation
TABLE-US-00009 [0329] TABLE 7 Soft Solid Antiperspirant
Compositions Formula XII Formula XIII Formula XIV Soft Solid Soft
Solid Soft Solid Aluminum Zirconium 26.5 26.5 26.5 Trichlorohydrex
Glycine Powder Cyclopentasiloxane Q.S. Q.S. Q.S. Dimethicone 5 5 5
Tribehenin 4.5 4.5 4.5 C18-36 acid 1.125 1.125 1.125 triglyceride
PPG-14 Butyl Ether 0.5 0.5 0.5 White Petrolatum 3 3 3
Beta-Cyclodextrin -- -- 3 complexed with perfume Perfume (defined
in 0.9 -- -- following table) Comparative Perfume A -- 0.9 --
Comparative Perfume C -- -- 1.5% QS - indicates that this material
is used to bring the total to 100%.
TABLE-US-00010 TABLE 8 Base Perfume CAS Number Percent of Anti-
Formulation of Anti- habituating Example PD Level from habituating
Material in Number Table 2 Anti-habituating Material Material
perfume XII.A 100% -- -- -- XII.B 99.998 Sauvignone 100*
851768-51-9 0.00002 XII.C 99.98 Sauvignone 100* 851768-51-9 0.0002
XII.D 99.8 Sauvignone 100* 851768-51-9 0.002 XII.E 99.5
4,7,7-trimethyl-6- 68398-18-5 0.5 thiabicyclo[3.2.1]octane XII.F
99.998 1-butylsulfanylbutane 544-40-1 0.002 XII.G 99.98
1-butylsulfanylbutane 544-40-1 0.02 XII.H 99.9 1-(1,3-thiazol-2-
24295-03-2 0.1 yl)ethanone XII.I 99.98 (2R,4S)-2-methyl-4-
59323-76-1 0.02 propyl-1,3-oxathiane XII.J 99.9 (2R,4S)-2-methyl-4-
59323-76-1 0.2 propyl-1,3-oxathiane XII.K 99.9975 2-methyl-3-
67952-65-2 0.0025 methylsulfanylpyrazine XII.L 99.99
1-pyrazin-2-ylethanone 22047-25-2 0.01 XII.M 99.5
3,7-dimethyloct-6- 51566-62-2 0.5 enenitrile XII.N 99.7 1H-indole
120-72-9 0.3 XII.O 99.6 Labienoxime** 81783-01-9 0.04 XII.P 99.9999
2-methoxy-3-(2- 24683-00-9 0.0001 methylpropyl)pyrazine XII.Q
99.9998 2-methoxy-3-(2- 24683-00-9 0.0002 methylpropyl)pyrazine
*Sauvignone 100 is supplied as a 1% active containing
5-methyl-5-sulfanylhexan-3-one **Labienxoxime is supplied as a 10%
active containing
(NE)-N-[(6E)-2,4,4,7-tetramethylnona-6,8-dien-3-ylidene]hydroxylamine
[0330] The formulations defined in Table 8 are various perfume
formulations to be used in Formula XII. Seventeen unique formulas
were made from Formula XII, each containing 0.9% of one of the
perfumes from example number XII.A through XII.Q, as defined in
Table 8.
[0331] Approximately 20 test subjects per usage group were
recruited for the study. The test subjects placed in the study were
assessed for their baseline threshold intensity according to the
Odor Detection Threshold (ODT) method defined above for the perfume
of interest that was in the product. Test subjects were placed in
nineteen study groups with an antiperspirant/deodorant and
instructed to apply 2 clicks per underarm (approximately 0.4 g per
underarm) throughout the four week study period, using no other
underarm products throughout the duration of the study. Their Odor
Detection Threshold (ODT) was measured again after 4 weeks of
usage. The average Odor Detection Threshold was calculated for each
usage group. Results are shown below.
[0332] The results indicate that the Odor Detection Threshold
increases significantly above baseline (test subjects are less
sensitive) for the usage group using the formula containing the
base perfume PD only, which was void of all sulfur and nitrogen
PRM's after 4 weeks of usage, indicating habituation. Surprisingly,
all components containing sulfur or nitrogen chemistry showed
improvement relative to the control. The data further suggests that
molecules containing sulfur or nitrogen having a sulfide moiety,
thiazole moiety, oxime moiety, or acetyl group produce the highest
resistance to habituation, therefore have the highest
anti-habituation index at levels below and above threshold
TABLE-US-00011 TABLE 9 Degree of Habituation (% change in group
average ODT) Results: Chemical Pink Daisy Perfume + Moiety of
Anti-habituation Antihabituating material Antihabituating % Change
in Index for four Product Used defined below for ODT Test Material
ODT at Week 4 week test Formula XII -- 3554 Highly containing
Habituating, thus XII.A no index Formula XII Sauvignone 100 (below
Thiol 166 Habituating, thus containing XII.B threshold) no index
Formula XII Sauvignone 100 (above Thiol 728 Habituating, thus
containing XII.C threshold) no index Formula XII Sauvignone 100
(saturation Thiol 364 Habituating, thus containing point) no index
XII.D Formula XII 4,7,7-trimethyl-6- Sulfide -61 4 containing XII.E
thiabicyclo[3.2.1]octane (above threshold) Formula XII
1-butylsulfanylbutane (below Sulfide -63 4 containing XII.F
threshold) Formula XII 1-butylsulfanylbutane (above Sulfide -31 4
containing threshold) XII.G Formula XII
1-(1,3-thiazol-2-yl)ethanone Thiazole -59 4 containing (above
threshold) XII.H Formula XII (2R,4S)-2-methyl-4-propyl- Oxathiane
413 Habituating, thus containing XII.I 1,3-oxathiane (below no
index threshold) Formula XII (2R,4S)-2-methyl-4-propyl- Oxathiane
218 Habituating, thus containing XII.J 1,3-oxathiane (above no
index threshold) Formula XII 2-methyl-3- Pyrazine -88 4 containing
methylsulfanylpyrazine comprising a XII.K (above threshold) Sulfide
moiety Formula XII 1-pyrazin-2-ylethanone Pyrazine -84 4 containing
XII.L (above threshold) comprising an acetyl moiety Formula XII
3,7-dimethyloct-6-enenitrile Nitrile 221 Habituating, thus
containing (above threshold) no index XII.M Formula XII 1H-indole
(above threshold) Indole 208 Habituating, thus containing no index
XII.N Formula XII Labienoxime (above Oxime -69 4 containing
threshold) XII.O Formula XII 2-methoxy-3-(2- Pyrazine 110 0
containing XII.P methylpropyl)pyrazine (below threshold) Formula
XII 2-methoxy-3-(2- Pyrazine 339 Habituating, thus containing
methylpropyl)pyrazine (above no index XII.Q threshold) Formula XIII
Contains Comparative 111 0 Perfume A Only Formula XIV Contains
Comparative 405 Habituating, thus Perfume C Only no index
[0333] It is believed that the differences seen from Example 2, in
which the base perfume had an anti-habituation index of 3 in the
four week test, vs. Example 3, in which the base perfume had
significant increase in ODT is beyond what is expected of
individual variation among panelists and were related to the
difference in perfume level (0.8% vs. 0.9%). Further, it is
believed that the base perfume would be habituating, even at a
lower perfume level if the test subjects used the product for a
longer duration. The addition of sulfur and nitrogen PRM's
consistently showed greater resistance to habituation as compared
to the control--regardless of perfume level tested.
Example 4
TABLE-US-00012 [0334] TABLE 10 Example Body Wash Compositions
Formula Formula Formula XV XVI XVII Body Wash Body Wash Body Wash
Sodium Laureth-3 Sulfate 27.85% 27.85% 27.85% (as 28% active) Water
Q.S. Q.S. Q.S. Sodium Lauryl Sulfate 10.34 10.34 10.34 (as 29%
active) Cocamidopropyl Betaine B 4.01 4.01 4.01 (30% active) Citric
Acid 0.18 0.18 0.18 Sodium Benzoate 0.3 0.3 0.3 Disodium EDTA 0.12
0.12 0.12 Methylchloroisothiazolinone/ 0.04 0.04 0.04
Methylisothiazolinone Sodium Chloride 2.35% 1.7% 1.6% Comparative
Perfume A 1.25% -- -- Comparative Perfume B -- 1.25% -- Perfume
Table 1 -- -- 1.25% QS - indicates that this material is used to
bring the total to 100%.
[0335] The formulations defined above contain various perfume
formulations. Formula XVII contains Perfume from Table 1. Formula
XV and XVI contain comparative perfumes.
[0336] Approximately 20 test subjects per usage group were
recruited for the study. The test subjects placed in the study were
assessed for their baseline threshold intensity according to the
Odor Detection Threshold (ODT) method defined above for the perfume
of interest that was in the product. Test subjects were placed in
three study groups with a body wash according to formulas XV, XVI,
and XVII and instructed to use the product daily, as they normally
would use their current cleansing product throughout the four week
study period, using no other cleansing products throughout the
duration of the study. Their Odor Detection Threshold (ODT) was
measured again after 2 weeks of usage, and again after 4 weeks of
usage. The average Odor Detection Threshold was calculated for each
usage group. Results are shown below.
[0337] The results indicate that the Odor Detection Threshold
increases significantly above baseline (test subjects are less
sensitive) for the usage group using Formula XV (comparative
perfume A) after 4 weeks of usage, indicating habituation. The
surprising result is that the test group using the body wash
containing the perfume from table 1 had the lowest degree of
habituation after 4 weeks of usage, indicating that they did not
become habituated to the scent of the product over time. Therefore,
the perfume used in formula XVII is has an anti-habituation index
of 0 when tested in a two week test and an anti-habituation index
of 4 when tested in a four week test.
TABLE-US-00013 TABLE 11 Degree of Habituation (% change in group
average ODT) Results: Type of Perfume Run % Change in % Change in
Product Used in the ODT test ODT at Week 2 ODT at Week 4 Formula XV
Comparative 554% 2948% from Example 3 Perfume A Formula XVI
Comparative -73% -4% from Example 3 Perfume B Formula XVII Perfume
from 121 -93% from Example 3 Table 1
Example 2
Preformed Amine Reaction Product
[0338] The following ingredients are weighted off in a glass vial:
[0339] 50% of the perfume material comprising one or more off the
perfumes claimed herein, for example, Table 1 perfumes A through G
[0340] 50% of Lupasol WF (CAS#09002-98-6) from BASF, is put at
60.degree. C. in warm water bath for 1 hour before use. Mixing of
the two ingredients is done by using the Ultra-Turrax T25 Basic
equipment (from IKA) during 5 minutes. When the mixing is finished
the sample is put in a warm water bath at 60.degree. C. for .+-.12
hours. A homogenous, viscous material is obtained.
[0341] In the same way as described above different ratios between
the components can be used:
TABLE-US-00014 Weight % Perfume Material 40 50 60 70 80 Lupasol WF
60 50 40 30 20
Example 3
84 wt % Core/16 wt % Wall Melamine Formaldehyde (MF) Capsule (PAD
Reservoir System
[0342] 25 grams of butyl acrylate-acrylic acid copolymer emulsifier
(Colloid C351, 25% solids, pka 4.5-4.7, (Kemira Chemicals, Inc.
Kennesaw, Ga. U.S.A.) is dissolved and mixed in 200 grams deionized
water. The pH of the solution is adjusted to pH of 4.0 with sodium
hydroxide solution. 8 grams of partially methylated methylol
melamine resin (Cymel 385, 80% solids, (Cytec Industries West
Paterson, N.J., U.S.A.)) is added to the emulsifier solution. 200
grams of one or more off the perfumes claimed herein, for example,
Table 1 perfumes A through G is added to the previous mixture under
mechanical agitation and the temperature is raised to 50.degree. C.
After mixing at higher speed until a stable emulsion is obtained,
the second solution and 4 grams of sodium sulfate salt are added to
the emulsion. This second solution contains 10 grams of butyl
acrylate-acrylic acid copolymer emulsifier (Colloid C351, 25%
solids, pka 4.5-4.7, Kemira), 120 grams of distilled water, sodium
hydroxide solution to adjust pH to 4.8, 25 grams of partially
methylated methylol melamine resin (Cymel 385, 80% solids, Cytec).
This mixture is heated to 70.degree. C. and maintained overnight
with continuous stirring to complete the encapsulation process. 23
grams of acetoacetamide (Sigma-Aldrich, Saint Louis, Mo., U.S.A.)
is added to the suspension. An average capsule size of 30 um is
obtained as analyzed by a Model 780 Accusizer.
Example 4
Process of Making a Polymer Assisted Delivery (PAD) Matrix
System
[0343] A mixture comprising 50% of one or more off the perfumes
claimed herein, for example, Table 1 perfumes A through G, 40% of
carboxyl-terminated Hycar.RTM.1300.times.18 (CAS#0068891-50-9) from
Noveon, (put at 60.degree. C. in warm water bath for 1 hour before
mixing) and 10% of Lupasol.RTM. WF(CAS#09002-98-6) from BASF (put
at 60.degree. C. in warm water bath for 1 hour before mixing).
Mixing is achieved by mixing for five minutes using a Ultra-Turrax
T25 Basic equipment (from IKA). After mixing, the mixture is put in
a warm water bath at 60.degree. C. for .+-.12 hours. A homogenous,
viscous and sticky material is obtained.
[0344] In the same way as described above different ratios between
the components can be used:
TABLE-US-00015 Weight % Table 1 Perfume 40 50 60 70 80 Lupasol
.RTM. WF 12 10 8 6 4 Hycar .RTM. 48 40 32 24 16 CTBN1300X18
TABLE-US-00016 Weight % Perfume composition 50 50 50 50 50 50 50 50
Lupasol .RTM. WF 2.5 5 7.5 10 12.5 15 17.5 20 Hycar .RTM. CTBN 47.5
45 42.5 40 37.5 35 32.5 30 1300X18
Example 5
Product Formulation--Fabric Softener
[0345] Non-limiting examples of product formulations containing
PRMs disclosed in the present specification perfume and amines
summarized in the following table.
TABLE-US-00017 EXAMPLES (% wt) XI XII XIII XIV XV XVI XVII XVIII
XIX XX FSA.sup.a 14 16.47 14 12 12 16.47 -- -- 5 5 FSA.sup.b --
3.00 -- -- -- FSA.sup.c -- -- 6.5 -- -- Ethanol 2.18 2.57 2.18 1.95
1.95 2.57 -- -- 0.81 0.81 Isopropyl -- -- -- -- -- -- 0.33 1.22 --
-- Alcohol Starch.sup.d 1.25 1.47 2.00 1.25 -- 2.30 0.5 0.70 0.71
0.42 Amine* 0.6 0.75 0.6 0.75 0.37 0.60 0.37 0.6 0.37 0.37 Perfume
X.sup.e 0.40 0.13 0.065 0.25 0.03 0.030 0.030 0.065 0.03 0.03 Phase
0.21 0.25 0.21 0.21 0.14 -- -- 0.14 -- -- Stabilizing Polymer.sup.f
Suds -- -- -- -- -- -- -- 0.1 -- -- Suppressor.sup.g Calcium 0.15
0.176 0.15 0.15 0.30 0.176 -- 0.1-0.15 -- -- Chloride DTPA.sup.h
0.017 0.017 0.017 0.017 0.007 0.007 0.20 -- 0.002 0.002
Preservative 5 5 5 5 5 5 -- 250.sup.j 5 5 (ppm).sup.i,j
Antifoam.sup.k 0.015 0.018 0.015 0.015 0.015 0.015 -- -- 0.015
0.015 Dye 40 40 40 40 40 40 11 30-300 30 30 (ppm) Ammonium 0.100
0.118 0.100 0.100 0.115 0.115 -- -- -- -- Chloride HCl 0.012 0.014
0.012 0.012 0.028 0.028 0.016 0.025 0.011 0.011 Structurant.sup.1
0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 0.01 Additional 0.8
0.7 0.9 0.5 1.2 0.5 1.1 0 1.0 0.9 Adjunct Perfume Deionized
.dagger. .dagger. .dagger. .dagger. .dagger. .dagger. .dagger.
.dagger. .dagger. .dagger. Water
.sup.aN,N-di(tallowoyloxyethyl)-N,N-dimethylammonium chloride.
.sup.bMethyl bis(tallow amidoethyl)2-hydroxyethyl ammonium methyl
sulfate. .sup.cReaction product of Fatty acid with
Methyldiethanolamine in a molar ratio 1.5:1, quaternized with
Methylchloride, resulting in a 1:1 molar mixture of
N,N-bis(stearoyl-oxy-ethyl) N,N-dimethyl ammonium chloride and
N-(stearoyl-oxy-ethyl) N,-hydroxyethyl N,N dimethyl ammonium
chloride. .sup.dCationic high amylose maize starch available from
National Starch under the trade name CATO .RTM.. .sup.ePerfume from
Table 1. .sup.fCopolymer of ethylene oxide and terephthalate having
the formula described in U.S. Pat. No. 5,574,179 at col.15, lines
1-5, wherein each X is methyl, each n is 40, u is 4, each R1 is
essentially 1,4-phenylene moieties, each R2 is essentially
ethylene, 1,2-propylene moieties, or mixtures thereof. .sup.gSE39
from Wacker .sup.hDiethylenetriaminepentaacetic acid. .sup.iKATHON
.RTM. CG available from Rohm and Haas Co. "PPM" is "parts per
million." .sup.jGluteraldehyde .sup.kSilicone antifoam agent
available from Dow Corning Corp. under the trade name DC2310.
.sup.1Hydrophobically-modified ethoxylated urethane available from
Rohm and Haas under the tradename Aculan 44. *One or more materials
comprising an amine moiety as disclosed in the present
specification. .dagger. balance
Example 6
Dry Laundry Formulations
TABLE-US-00018 [0346] % w/w granular laundry detergent composition
Component A B C D E F G Brightener 0.1 0.1 0.1 0.2 0.1 0.2 0.1 Soap
0.6 0.6 0.6 0.6 0.6 0.6 0.6 Ethylenediamine disuccinic acid 0.1 0.1
0.1 0.1 0.1 0.1 0.1 Acrylate/maleate copolymer 1.5 1.5 1.5 1.5 1.5
1.5 1.5 Hydroxyethane di(methylene 0.4 0.4 0.4 0.4 0.4 0.4 0.4
phosphonic acid) Mono-C.sub.12-14 alkyl, di-methyl, 0.5 0.5 0.5 0.5
0.5 0.5 0.5 mono-hydroyethyl quaternary ammonium chloride Linear
alkyl benzene 0.1 0.1 0.2 0.1 0.1 0.2 0.1 Linear alkyl benzene
sulphonate 10.3 10.1 19.9 14.7 10.3 17 10.5 Magnesium sulphate 0.4
0.4 0.4 0.4 0.4 0.4 0.4 Sodium carbonate 19.5 19.2 10.1 18.5 29.9
10.1 16.8 Sodium sulphate 29.6 29.8 38.8 15.1 24.4 19.7 19.1 Sodium
Chloride 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Zeolite 9.6 9.4 8.1 18 10 13.2
17.3 Photobleach particle 0.1 0.1 0.2 0.1 0.2 0.1 0.2 Blue and red
carbonate speckles 1.8 1.8 1.8 1.8 1.8 1.8 1.8 Ethoxylated Alcohol
AE7 1 1 1 1 1 1 1 Tetraacetyl ethylene diamine 0.9 0.9 0.9 0.9 0.9
0.9 0.9 agglomerate (92 wt % active) Citric acid 1.4 1.4 1.4 1.4
1.4 1.4 1.4 PDMS/clay agglomerates (9.5% 10.5 10.3 5 15 5.1 7.3
10.2 wt % active PDMS) Polyethylene oxide 0.2 0.2 0.2 0.2 0.2 0.2
0.2 Enzymes e.g. Protease (84 mg/g 0.2 0.3 0.2 0.1 0.2 0.1 0.2
active), Amylase (22 mg/g active) Suds suppressor agglomerate 0.2
0.2 0.2 0.2 0.2 0.2 0.2 (12.4 wt % active) Sodium percarbonate
(having 7.2 7.1 4.9 5.4 6.9 19.3 13.1 from 12% to 15% active AvOx)
Additional Adjunct Perfume** 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Amine* 0.1
0.5 0.0 0.01 0.02 0.00 0.07 Perfume Delivery System As 0.05 0.0 0.1
0.0 0.2 0.4 0.0 Disclosed In The Present Specification Including
Examples 2-4 Perfume Table 1 0.3 0.4 0.01 0.02 0.04 0.1 0.1 Water
1.4 1.4 1.4 1.4 1.4 1.4 1.4 Misc 0.1 0.1 0.1 0.1 0.1 0.1 0.1 Total
Parts 100 100 100 100 100 100 100 *One or more materials comprising
an amine moiety as disclosed in the present specification.
**Optional
Example 7
Liquid Laundry Formulations (HDLs)
TABLE-US-00019 [0347] Ingredient HDL 1 HDL 2 HDL3 HDL4 HDL 5 HDL 6
Alkyl Ether Sulphate 0.00 0.50 12.0 12.0 6.0 7.0 Dodecyl Benzene
8.0 8.0 1.0 1.0 2.0 3.0 Sulphonic Acid Ethoxylated Alcohol 8.0 6.0
5.0 7.0 5.0 3.0 Citric Acid 5.0 3.0 3.0 5.0 2.0 3.0 Fatty Acid 3.0
5.0 5.0 3.0 6.0 5.0 Ethoxysulfated 1.9 1.2 1.5 2.0 1.0 1.0
hexamethylene diamine quaternized Diethylene triamine penta 0.3 0.2
0.2 0.3 0.1 0.2 methylene phosphonic acid Enzymes 1.20 0.80 0 1.2 0
0.8 Brightener (disulphonated 0.14 0.09 0 0.14 0.01 0.09 diamino
stilbene based FWA) Cationic hydroxyethyl 0 0 0.10 0 0.200 0.30
cellulose Poly(acrylamide-co- 0 0 0 0.50 0.10 0
diallyldimethylammonium chloride) Hydrogenated Castor Oil 0.50 0.44
0.2 0.2 0.3 0.3 Structurant Boric acid 2.4 1.5 1.0 2.4 1.0 1.5
Ethanol 0.50 1.0 2.0 2.0 1.0 1.0 1,2 propanediol 2.0 3.0 1.0 1.0
0.01 0.01 Glutaraldehyde 0 0 19 ppm 0 13 ppm 0 Diethyleneglycol
(DEG) 1.6 0 0 0 0 0 2,3-Methyl-1,3- 1.0 1.0 0 0 0 0 propanediol (M
pdiol) Mono Ethanol Amine 1.0 0.5 0 0 0 0 NaOH Sufficient To pH 8
pH 8 pH 8 pH 8 pH 8 pH 8 Provide Formulation pH of: Sodium Cumene
2.00 0 0 0 0 0 Sulphonate (NaCS) Silicone (PDMS) emulsion 0.003
0.003 0.003 0.003 0.003 0.003 Additional Adjunct 0.7 0.5 0.8 0.6
0.6 0.5 Perfume** Amine* 0.01 0.10 0.0 0.10 0.20 0.05 Perfume from
Table 1 0.02 0.15 0.10 0.2 0.3 0.05 Perfume Delivery System 0.2
0.02 0.4 0.0 0.0 0.0 As Disclosed In The Present Specification
Including Examples 2-4 Water Balance Balance Balance Balance
Balance Balance *One or more materials comprising an amine moiety
as disclosed in the present specification. **Optional.
Example 8
Deodorant Compositions
TABLE-US-00020 [0348] Ingredient VI VII VIII IX X Product Solid
Solid Solid Solid Aerosol Form Deodorant Deodorant Deodorant
Deodorant Deodorant or Body Spray dipropylene 45 22 20 30 20 glycol
propylene 22 45 22 glycol tripopylene 25 glycol Glycerine 10 PEG-8
20 ethanol QS Water QS QS QS QS sodium 5.5 5.5 5.5 5.5 stearate
tetra sodium 0.05 0.05 0.05 0.05 EDTA sodium 0.04 0.04 0.04 0.04
hydroxide triclosan 0.3 0.3 0.3 0.3 Perfume 0.5 1.0 1.0 0.5 1.5
Table 1 Propellant 40 (1,1 difluoro- ethane) QS - indicates that
this material is used to bring the total to 100%.
Shampoo Compositions
TABLE-US-00021 [0349] EXAMPLE COMPOSITION 20 21 Ammonium Laureth
Sulfate (AE.sub.3S) 6.00 6.00 Ammonium Lauryl Sulfate (ALS) 10.00
10.00 Laureth-4 Alcohol 0.90 0.90
Trimethylammoniopropylmethacrylamide 0.25 -- chloride-N-Acrylamide
copolymer.sup.(25) Trihydroxystearin.sup.(7) 0.10 0.10 Perfume
Table 1 0.60 0.60 Sodium Chloride 0.40 0.40 Citric Acid 0.04 0.04
Sodium Citrate 0.40 0.40 Sodium Benzoate 0.25 0.25 Ethylene Diamine
Tetra Acetic Acid 0.10 0.10 Dimethicone.sup.(9,10,11) 1.00.sup.(9)
1.00.sup.(9) Water and Minors Q.S. Q.S.
Lotion Example:
TABLE-US-00022 [0350] Example 1 Example 2 Example 3 Water Phase:
Water qs qs qs Glycerin 5.0 5.0 5.0 Disodium EDTA 0.1 0.1 0.1
Methylparaben 0.2 0.2 0.2 Niacinamide 4.0 4.0 4.0 D-panthenol 0.5
0.5 0.5 Phenylbenzimidazole Sulfonic 1.0 1.0 1.0 Acid Pentylene
Glycol 1.0 1.0 1.0 Benzyl alcohol 0.25 0.25 0.25 Triethanolamine
0.64 0.64 0.64 Oil Phase: Isopropyl Isostearate 1.33 1.33 1.33
Octisalate 4.0 4.0 4.0 Octocrylene 1.0 1.0 -- Avobenzone 2.0 2.0 --
Petrolatum 2 2 2 Shea Butter 0.5 0.5 0.5 Vitamin E Acetate 0.1 0.1
0.1 Ethylparaben 0.2 0.2 0.2 Propylparaben 0.2 0.2 0.2 Cetyl
alcohol 0.3 0.3 0.3 Stearyl alcohol 0.4 0.4 0.4 Behenyl alcohol 0.4
0.4 0.4 Cetearyl Glucoside/Cetearyl 0.3 0.3 0.3 Alcohol.sup.1
PEG-100 stearate 0.3 0.3 0.3 Tinosorb S.sup.5 -- 1 2 Synovea
DOI.sup.6 4.0 5.0 6.0 Thickener: Sepigel .TM. 305.sup.2 2.25 2.25
2.25 Additional Ingredients: Perfume Table 1 1.0 0.75 1.25
Microthene FN510.sup.3 1.0 1.0 1.0 Polysorbate 20 0.5 0.5 0.5 Dow
Corning .TM. 1503.sup.4 2.0 2.0 2.0 Total: 100% 100% 100%
.sup.1Emulgade .TM. PL68/50 from Cognis .TM. .sup.2Polyacrylamide,
C13-14 isoparaffin, and laureth-7 from Seppic .TM.
.sup.3Polyethylene homopolymer spheres from Equistar .TM.
.sup.4Dimethicone and dimethiconol from Dow Corning .TM.
.sup.5Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine from BASF .TM.
.sup.6Dioctanoyl Isosorbide from Syntheon .TM.
[0351] In a suitable vessel, the water phase ingredients are
combined and heated to 75.degree. C. In a separate suitable vessel,
the oil phase ingredients are combined and heated to 75.degree. C.
Next the oil phase is added to the water phase and the resulting
emulsion is milled (eg., with a Tekmar T-25). The thickener is then
added to the emulsion and the emulsion is cooled to 45.degree. C.
while stirring. At 45.degree. C., the remaining additional
ingredients are added. The product is then cooled with stirring to
30.degree. C., milled again, and then poured into suitable
containers.
[0352] The dimensions and values disclosed herein are not to be
understood as being strictly limited to the exact numerical values
recited. Instead, unless otherwise specified, each such dimension
is intended to mean both the recited value and a functionally
equivalent range surrounding that value. For example, a dimension
disclosed as "40 mm" is intended to mean "about 40 mm".
[0353] All documents cited in the Detailed Description of the
Invention are, in relevant part, incorporated herein by reference;
the citation of any document is not to be construed as an admission
that it is prior art with respect to the present invention. To the
extent that any meaning or definition of a term in this document
conflicts with any meaning or definition of the same term in a
document incorporated by reference, the meaning or definition
assigned to that term in this document shall govern.
[0354] While particular embodiments of the present invention have
been illustrated and described, it would be obvious to those
skilled in the art that various other changes and modifications can
be made without departing from the spirit and scope of the
invention. It is therefore intended to cover in the appended claims
all such changes and modifications that are within the scope of
this invention.
* * * * *