U.S. patent application number 13/445091 was filed with the patent office on 2012-08-09 for cartridge and medical delivery system accommodating such cartridge.
This patent application is currently assigned to Novo Nordisk A/S. Invention is credited to Morten Baek Jensen, Lars Thougaard Kristensen, Lars Korsbjerg Nielsen, Kim Steengaard.
Application Number | 20120203185 13/445091 |
Document ID | / |
Family ID | 8160683 |
Filed Date | 2012-08-09 |
United States Patent
Application |
20120203185 |
Kind Code |
A1 |
Kristensen; Lars Thougaard ;
et al. |
August 9, 2012 |
Cartridge And Medical Delivery System Accommodating Such
Cartridge
Abstract
A cartridge having a distal end provided with a mechanical
coding. The coding has the form of a circular protrusion where the
circular outer diameter is dedicated a specific concentration of
insulin contained in the cartridge. The distal end of the cartridge
is fitted in to a circular contour in the housing. The outer
diameter of the protrusion on the distal end of the cartridge is
chosen as a larger diameter for a higher concentration of insulin.
In this way only a cartridge containing the correct concentration
or a lower concentration fits into a delivery system designed for a
specific concentration of insulin.
Inventors: |
Kristensen; Lars Thougaard;
(Herlev, DK) ; Nielsen; Lars Korsbjerg;
(Birkeroed, DK) ; Steengaard; Kim; (Birkeroed,
DK) ; Jensen; Morten Baek; (Naerum, DK) |
Assignee: |
Novo Nordisk A/S
Bagsvaerd
DK
|
Family ID: |
8160683 |
Appl. No.: |
13/445091 |
Filed: |
April 12, 2012 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
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12552566 |
Sep 2, 2009 |
8177767 |
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13445091 |
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11784738 |
Apr 9, 2007 |
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12552566 |
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10230428 |
Aug 23, 2002 |
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11784738 |
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60317307 |
Sep 5, 2001 |
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Current U.S.
Class: |
604/189 ;
604/404 |
Current CPC
Class: |
A61J 2205/40 20130101;
A61M 5/14566 20130101; A61M 2205/6045 20130101; A61M 5/1452
20130101; A61M 5/24 20130101 |
Class at
Publication: |
604/189 ;
604/404 |
International
Class: |
A61J 1/14 20060101
A61J001/14; A61M 5/31 20060101 A61M005/31 |
Foreign Application Data
Date |
Code |
Application Number |
Aug 27, 2001 |
DK |
PA 2001 01268 |
Claims
1. A medication delivery system for delivering medication from a
cartridge, the medication delivery system comprising: a medication
delivery device that is calibrated and designed for a specific
concentration of a medication and wherein the medication delivery
device has a cartridge receiving portion structured to accept only
cartridges having a specific mechanical coding that corresponds to
the concentration for which the device is designed and calibrated,
or a lower concentration; a cartridge containing one of a plurality
of different concentrations of medication, the cartridge containing
at least one mechanical coding selected from a plurality of
mechanical codings, the mechanical coding(s) comprising at least
one protrusion(s) shaped as a raised point, which raised point(s)
are oriented around the outer cartridge surface; and wherein the
selected mechanical coding(s) allow(s) the cartridge to be used
only in a delivery device designed and calibrated for the
concentration indicated by the selected mechanical coding(s), or a
lower concentration, wherein the mechanical coding(s) comprise
protrusion(s) having the same or different length L from a distal
surface, and wherein cartridges having a higher concentration of
medication which the device is designed and calibrated for are not
insertable into the medication delivery device.
2. The medication delivery system of claim 1, wherein the
medication is insulin and the medication delivery system is an
injection device and wherein at least one of the mechanical codings
is indicative of 100 IU per ml insulin and wherein the medication
delivery device is designed and calibrated for 100 IU per ml
medications and wherein the cartridge receiving portion of the
medication delivery device accepts cartridges having the mechanical
coding thereby allowing only specific cartridges containing 100 IU
per ml concentrations to be inserted and used with the medication
delivery system.
3. The medication delivery system of claim 2 wherein at least one
of the mechanical codings is indicative of an insulin having a
concentration of something other than IU 100 insulin.
4. The medication delivery system of claim 1, wherein the
protrusions form an asymmetric pattern around the cartridge when
viewing a cross section of the cartridge though the
protrusions.
5. The medication delivery system of claim 1, wherein the
protrusions form an symmetric pattern around the cartridge when
viewing a cross section of the cartridge though the
protrusions.
6. A cartridge comprising: a medication storing portion suitable
for use in a medication delivery device, wherein the medication
storing portion of the cartridge is adapted to store a medicament
that is available in a plurality of concentrations; at least one
mechanical coding comprising at least one protrusion(s) shaped as a
raised point, which raised point(s) are oriented around the outer
cartridge surface; and wherein at least the specific orientation of
the protrusions are indicative of a specific concentration of the
medicament; and wherein the mechanical coding is structured to
allow the cartridge to be used only in medication delivery devices
that are configured to mechanically accept the specific orientation
of the protrusions.
7. A cartridge according to claim 6, wherein the medicament
comprises an insulin.
8. A cartridge according to claim 7, wherein the mechanical coding
is on an adapter that is disposed on an outer cylindrical wall of
the cartridge wherein the adapter is in the form of a sleeve that
jackets at least the medicaton storing portion of the
cartridge.
9. A medication cartridge adapted for use with a medication
delivery device, the cartridge comprising: a body having a
cylindrical wall around a medication storing compartment; a
medication selected from a group of medications suitable for
delivery with the medication delivery device and stored in the
medication storing compartment; and a mechanical coding; wherein
the mechanical coding comprises at least one protrusion(s) shaped
as a raised point, which raised point(s) are oriented around the
outer cartridge surface; wherein the mechanical coding is
indicative of the specific type of medication in the cartridge, and
allows the cartridge to be used only in medications delivery
devices that are configured to mechanically accept the mechanical
coding and the cartridge, and wherein cartridges having a higher
concentration of medication which the device is designed and
calibrated for are not insertable into the medication delivery
device.
10. The medication cartridge of claim 9, wherein the specific type
of medication is a 100 IU per ml concentration of medication.
11. The medication cartridge of claim 9, wherein the mechanical
coding is integral with the cylindrical wall of the cartridge.
12. The medication cartridge of claim 9, wherein the mechanical
coding is located a distance L from a distal end of the cartridge
so that the mechanical coding is located between a distal and a
proximal end of the cartridge body and wherein the protrusion has a
diameter D that is larger than the diameter of the cylindrical wall
of the body.
13. The medication cartridge of claim 9, wherein the protrusion
that forms the mechanical coding is located on an adapter sleeve
that jackets the cylindrical wall.
14. The medication cartridge of claim 13, wherein the mechanical
coding is structured to align the cartridge axially within a
cartridge receiving portion of one or more of the medication
delivery devices that have been determined in advance to be
suitable for use with the medication in the cartridge.
15. The medication cartridge of claim 14, wherein the medication is
an insulin and wherein the mechanical coding has a shape
complimentary to the shape of the cartridge receiving portion.
16. The medication cartridge of claim 9, wherein a larger diameter
mechanical coding is indicative of a higher concentration of the
medicament adapted to be stored in the medication storing
compartment.
17. A method of using a medication delivery system for delivering
medication from a cartridge, the method comprising: providing a
medication delivery device that is calibrated and designed for a
specific concentration of a medication and wherein the medication
delivery device has a cartridge receiving portion with a shape and
diameter so that the medication delivery device is structured to
accept only cartridges having a specific mechanical coding that
corresponds to the concentration for which the device is designed
and calibrated, or a lower concentration; providing a cartridge
containing one of a plurality of different concentrations of
medication, the cartridge containing at least one mechanical coding
selected from a plurality of mechanical codings, the mechanical
coding(s) comprising at least protrusion(s) shaped as a raised
point, which raised point(s) are oriented around the outer
cartridge surface that allows the cartridge to fit into the
cartridge receiving portion of the medication delivery device and;
and wherein the selected mechanical coding(s) allow(s) the
cartridge to be used only in a delivery device designed and
calibrated for the concentration indicated by the selected
mechanical coding(s), or a lower concentration, wherein the
mechanical coding(s) comprise protrusion(s) having the same or
different length L from a distal surface, and wherein cartridges
having a higher concentration of medication which the device is
designed and calibrated for are not insertable into the medication
delivery device.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation of copending U.S.
application Ser. No. 12/552,566 filed Sep. 2, 2009, which is a
continuation of U.S. application Ser. No. 11/784,738 filed Apr. 9,
2007, which is a continuation of U.S. application Ser. No.
10/230,428 filed on Aug. 23, 2002 (published as U.S. 2003-0078195
A1), and claims priority of Danish Application No. PA 2001 01268
filed Aug. 27, 2001 and U.S. Provisional Application 60/317,307
filed Sep. 5, 2001, the contents of which are fully incorporated
herein by reference.
THE TECHNICAL FIELD OF THE INVENTION
[0002] The invention relates to ampoules or cartridges for medical
delivery systems. Such cartridges are commonly shaped as a glass or
plastic tube being at one end closed by a piston, which may be
pressed into the tube to expel the content of the tube at the other
end of the tube. This other end is often formed as a bottleneck,
the outer end of which may be pierced by a conduit such as an
injection needle or a catheter through which the content is
expelled.
[0003] The invention furthermore relates to a medical delivery
system accommodating such a cartridge.
DESCRIPTION OF RELATED ART
[0004] Cartridges are widely known for various medical delivery
systems. They are especially used for insulin delivery systems, and
are usually supplied pre-filled with either 1.5 ml of insulin or
3.0 ml of insulin.
[0005] The typical diabetes patient will require a certain amount
of insulin either injected or infused into their body every day.
The patient loads a cartridge containing the insulin into either an
injection system or a pump system and injects or infuses the
insulin into their body at a prescribed rate, either through an
injection needle or through a catheter having one end inserted into
their body. The injection needle or the catheter is at the other
end connected to the cartridge. Once the cartridge is empty it is
disposed of and a new cartridge is loaded into the delivery
system.
[0006] Glass is the most preferred material for cartridges
containing insulin, however cartridges moulded from plastic such as
shown in WO 98.56438 is on the verge of a break through.
[0007] A prior art glass cartridge is disclosed in EP 0 549 694.
This glass cartridge has an adapter mounted on the distal end of
the glass cartridge. The adapter has a bore for receiving the neck
part of the glass cartridge, which neck part is closed of by a
metal cover. The inner wall of the bore is provided with gripping
elements for gripping behind the edge of the metal cover when the
neck part is mounted in the bore.
DESCRIPTION OF THE INVENTION
[0008] Traditionally, cartridges containing fluid medication have
been used with medical delivery systems worldwide for invasive
delivery of various types of fluid medicines. However, in typical
medical delivery systems a cartridge is simply inserted into the
delivery system without the system having any method of determining
if the medicament contained in the cartridge is the correct type of
medication for that specific delivery system. The user must
manually check the cartridge to make sure that the medication is
the correct one. This is quit important, since the administration
of a incorrect kind of medication or of an incorrect dosage could
result in injury or death.
[0009] In order to overcome the drawbacks of the prior art it is
here suggested to provide the cartridge with a mechanical coding,
which mechanical coding has to fit into a specific contour in the
medical delivery system in order to allow correct mounting of the
cartridge in the medical delivery system.
[0010] By providing the cartridge with a mechanical coding it is
ensured that the specific cartridge will only fit into a medical
delivery system having a cartridge receiving part with a contour
conforming to the shape of the mechanical coding of the
cartridge.
[0011] In some medical delivery systems however, the conduit
delivering the medication into the body of the patient are
connected directly to the cartridge. The connecting part of the
conduit, which are usually referred to as the conduit connector can
then be made with an interior contour, which fits over the specific
contour of the mechanical coding of the cartridge.
[0012] The shape of the contour of the cartridge and the
corresponding part of the medical delivery system or the conduit
connector can be any geometrical shape wanted, e.g. triangular,
square or any other polygon.
[0013] In this way the manufacture of the medicament can ensure
that a specific medicament contained in a cartridge having a
mechanical coding only can be dispensed from a specific medical
delivery system and/or through a specific conduit.
[0014] The mechanical coding can either be moulded as an integral
part of the cartridge, or it can be added to the cartridge in the
form of e.g. an adapter, a sleeve or a jacket connected to the
cartridge. The mechanical coding could also be provided as a part
of the cartridge sealing.
[0015] The mechanical coding could also be provided as one or more
depressions provided either in the cartridge or in the adapter. The
medical delivery system would then be provided with a stud, which
has to fit into the depression or depressions in order to allow the
cartridge to be connected to the medical delivery system.
[0016] When the mechanical coding is made as one or more
protrusions extending radial outwards from the outer cartridge
surface, which is cylindrical, the cartridge can perform like a key
while the cartridge receiving part of the medical delivery system
or the conduit connector receiving the cartridge can perform as a
key hole.
[0017] Instead of providing the outer cartridge surface with the
mechanical coding, an adapter carrying the mechanical coding can be
mounted on the cartridge at its distal end. This solution is to be
preferred for glass cartridges.
[0018] When the mechanical coding is made as one or more
protrusions extending radial outwards from the outer adapter
surface, which is cylindrical, the outer adapter mounted on the
cartridge can perform like a key while the cartridge receiving part
of the medical delivery system or the conduit connector receiving
the cartridge can perform as a key hole.
[0019] By letting the protrusion or protrusions located on the
outer surface of the cartridge or the adapter form a substantial
circular protrusion, the outer surface of either the cartridge or
the adapter can be made rotational symmetrical.
[0020] The protrusions can be formed as one circular protrusion
covering substantially 360 degrees of the outer surface, or as a
number of individual protrusions preferably located along a circle
on the outer periphery of the outer surface of the cartridge or the
adapter, such that the outer surface is rotational symmetrical,
hence the location of the cartridge or the adapter in relation to
the cartridge receiving part of the medical delivery system or the
conduit connector receiving the cartridge is of importance.
[0021] The mating key hole of the cartridge receiving part of the
medical delivery system or
[0022] the conduit connector needs in its simplest form just be a
hole having an inside contour conforming to the outside diameter of
the circular protrusion.
[0023] Cartridges can then be made to fit specific delivery systems
simply by mating the outside diameter of the circular protrusion
with the inside contour of the cartridge receiving part of the
medical delivery system or with the inside contour of the conduit
connector.
[0024] The circular protrusion can either be made as one or a few
protrusions substantially covering 360 degrees of the outer
cartridge surface or the outer adapter surface, or it can be made
as a number of raised islands located along the outer cartridge
surface or the outer adapter surface. The number of raised island
can vary from one and up.
[0025] The diameter of the circular protrusion can be utilized to
indicate a parameter of the medicament contained in the specific
cartridge. The parameter could e.g. be the type of medicament or it
could be the concentration of the medicament.
[0026] When the cartridge contains insulin for treating diabetes it
is to be preferred that the specific diameter of the circular
protrusion is dedicated a specific concentration of insulin. Most
insulin sold today has a concentration of 100 International Units
(IU) pr. millilitre of insulin. Recently insulin with a
concentration of 200 IU pr. ml. has emerged.
[0027] If a patient by accident loads a cartridge containing
insulin with a concentration of 200 IU pr. ml. into a medical
delivery system which are designed for use with insulin having a
concentration of 100 IU pr. ml the patient will inject twice the
number of International Units needed while the medical delivery
systems normally are designed to expel a given quantity of insulin.
The consequences of this could be fatal.
[0028] It is therefore of the outmost importance that cartridges
containing insulin with a concentration of 200 IU pr. ml are
effectively prevented from being used in medical delivery systems
designed to handle insulin with 100 IU pr. ml.
[0029] This is done by providing cartridges containing insulin with
a concentration of 200 IU pr. ml. with a circular protrusion with a
larger diameter than a cartridge containing insulin with only 100
IU pr. ml. When at the same time the inside contour of the
cartridge receiving part of the medical delivery system or the
conduit connector for a 100 IU pr. ml system is made to fit the
diameter of the circular protrusion of the adapter of a cartridge
containing insulin with a 100 IU pr. ml, it is ensured that a
cartridge containing insulin with a concentration of 200 IU pr. ml
can not be used in such a delivery system while the diameter of the
circular protrusion of this cartridge is to large to fit into the
inside contour of the cartridge receiving part of the medical
delivery system or the conduit connector of a 100 IU pr. ml
system.
[0030] This system can be expanded to also encompass insulin with
even higher concentrations, such as 300 or 400 IU pr. ml simply by
moulding the circular protrusions carried on the cartridges of
these higher concentrations with larger diameters, such that the
circular protrusion of a cartridge containing insulin with a
specific concentration do not fit into the cartridge receiving part
of a medical delivery system and/or into a conduit connector for a
medical delivery system designed for a lower concentration of
insulin.
[0031] When using cartridges with circular protrusions with larger
diameters for higher concentrations of insulin it will however be
possible for a patient to fit a cartridge containing insulin with a
lower concentration into the cartridge receiving part of a medical
delivery system and/or into a conduit connector of system designed
for a higher concentration of insulin. The result of this is that
the patient does not get insulin enough for the correct treatment,
which is a major inconvenience for that individual patient, but
which is not a fatal incident, and which the patient will discover
next time the blood glucose level is measured.
[0032] It is furthermore an object of the present invention to
provide a medical delivery system accommodating a cartridge
carrying a mechanical coding.
[0033] Such a medical delivery system may have a housing for
accommodating a cartridge with an inside shape conforming to the
outside shape of the mechanical coding, such that only cartridges
that are suitable for use with the medical delivery system are
capable of being received by the medical delivery system.
[0034] In some medical delivery systems, the conduit delivering the
fluent medicament is connected directly to the cartridge by use of
a conduit connector located at one end of the conduit. This conduit
connector will then have a contour conforming to the mechanical
coding on the outer cartridge surface or the adapter surface, such
that only cartridges containing a fluid medicament suitable for the
specific medical delivery system can be connected to the conduit of
that specific medical delivery system.
[0035] The medicament contained in the cartridge is preferably
insulin, the mechanical coding is a circular protrusion and the
specific outside diameter of the circular protrusion is dedicated a
specific concentration of insulin and the outside diameter is
chosen as a larger diameter for a higher concentration.
[0036] In this way it is ensured that only insulin with
concentrations suitable for or lower than the insulin concentration
a specific insulin delivery system or conduit is designed for can
actually be used in that specific insulin delivery system or with
that specific conduit.
Definitions
[0037] In the present context, the term "Medical delivery system"
is taken to mean any system for invasive bringing a fluid
medicament into a human body. The most commonly used medical
delivery system is an injection system or an infusion system. In an
injection system a predetermined quantity of the medicament are
brought into the human body at one time through a conduit such as
an injection needle temporarily inserted in the body. In an
infusion system a quantity of the medicament is pumped via a pump
system into the human body at a small constant rate through a
conduit such as a catheter constantly inserted in the human
body.
[0038] Although the wording "human body" is used through out this
application, the medical delivery system could as well be used on
any other mammal body without dispersing from the scope of the
claims.
[0039] It is to be understood that the wording "protrusion", refers
to an element or a part that protrudes from a surface disregarding
the form or the shape of the element or the part, while the term
"circular protrusion" refers to a part which continuously protrudes
from a circular surface substantially at all 360 degrees round the
surface. The circular protrusion can however be made from a number
of raised points located at a circle at the periphery of the
surface without dispersing from the scope of the claims.
[0040] In the present context, the term "Conduit connector" is
taken to mean a part or an element which is connected to the
conduit or moulded as an integral part of the conduit, and which
can be connected directly to either the cartridge, to the adapter
or to the medical delivery system.
BRIEF DESCRIPTION OF THE DRAWINGS
[0041] The invention will be explained more fully below in
connection with a preferred embodiment and with reference to the
drawings in which:
[0042] FIG. 1 Shows an adapter mounted on a cartridge.
[0043] FIG. 2 Shows the adapter of FIG. 1 seen from above
[0044] FIG. 3 Shows an adapter with two circular protrusions
protruding from the outer adapter surface.
[0045] FIG. 4 Shows an adapter with a number of raised islands
protruding forming the outer adapter surface.
[0046] FIG. 5 Shows an adapter where the protrusion has the same
width as the extension of the outer adapter surface.
[0047] FIG. 6 Shows an adapter, which can be horizontally mounted
on the cartridge.
[0048] The figures are schematic and simplified for clarity, and
they just show details, which are essential to the understanding of
the invention, while other details are left out. Throughout, the
same reference numerals are used for identical or corresponding
parts.
DETAILED DESCRIPTION OF EMBODIMENTS:
[0049] Initially it may be convenient to define that, the term
"distal end" of the cartridge 2 or the adapter 1 is meant to refer
to the end carrying the conduit through which the medicine is
expelled, whereas the term "proximal end" is meant to refer to the
opposite end.
[0050] FIG. 1 shows the adapter 1 mounted on a cartridge 2. The
cartridge 2 is closed of by a metal cover 3 which are folded over
the bottleneck of the cartridge 2 and beaded at the lower edge. The
adapter 1 has a distal end surface 4, a proximal end surface 5 and
an outer adapter surface 6 there between. The adapter 1 further has
a longitudinal bore conforming the outer diameter of the metal
cover 3. The adapter 1 is mounted on the cartridge 2 simply by
pushing the adapter 1 over the metal cover 3. This is possible
since the inside bore of the adapter has a diameter larger than the
outside diameter of the metal cover 3. The inside surface 7 of this
bore is provided with a number of gripping elements 8, usually
there are three such gripping elements 8 located with a 120 degrees
displacement. The diameter formed by these three gripping elements
8 are smaller than the diameter of the metal cover 3, such that the
gripping elements 8 will grip behind the beaded end of the metal
cover 3 when the adapter 1 is mounted on the cartridge 2.
[0051] The outer adapter surface 6 is provided with one or more
protrusions 9, which protrusion 9 extends radial outwards from the
outer adapter surface. The protrusion 9 can as shown in FIG. 2 have
a circular form covering 360 degrees of the outer adapter surface
6.
[0052] The circular protrusion 9 has an outer diameter, which can
be different from one adapter 1 to another adapter 1 as indicated
with dotted lines 10.
[0053] The cartridge receiving part 11 is provided with a circular
bore 13, which receives the adapter 1 when the cartridge 2 is
mounted in the cartridge receiving part 11. For other types of
cartridge receiving parts 12 indicated with dotted lines, the bore
14 could have a different diameter.
[0054] Referring to FIGS. 1 and 6, a specific outside diameter of
the circular protrusion 9, 10 is dedicated to a specific
concentration of the insulin contained in the cartridge 2. The
cartridge 2 containing the lowest concentration is provided with an
adapter 1 having only a small outside diameter of the circular
protrusion 9, while the larger concentrations are provided with an
adapter 1 having a larger diameter of the circular protrusion
10.
[0055] The same is the case for the diameter of the bore of the
cartridge receiving part 11. The cartridge receiving part 11 on a
medical delivery system designed for low concentrations has the
smallest diameter of the bore 13, while the cartridge receiving
part 12 on a medical delivery system for handling larger
concentrations has a larger bore 14.
[0056] As illustrated in FIG. 6 a cartridge receiving part 11 on a
medical delivery system designed for 100 IU pr. ml can only receive
the adapter 1 of an cartridge 2 containing insulin with a 100 IU
pr. ml. concentration, which is indicated by the outside diameter
of the circular protrusion 9, while the cartridge receiving part 12
on a system designed for 200 IU pr. ml. can receive both the
adapter 1 of a cartridge 2 containing insulin with a concentration
of 100 IU pr. ml and the adapter 1 of a cartridge 2 containing
insulin with a concentration of 200 IU pr. ml, indicated by a
circular protrusion 10 having a larger outside diameter.
[0057] Although the 100 IU cartridge 2 of FIG. 6 is described as
being a cartridge 2 with an adapter 1 mounted thereto, it could as
well be a cartridge 2 moulded from plastic with the protrusion 9
moulded as an integral part of the cartridge 2.
[0058] The cartridge receiving part 15 of medical delivery system
designed for 300 IU pr. ml is able of handle both the previous
mentioned adapters 1 having circular protrusions 9, 10 as well as
an adapter of a cartridge having a circular protrusion 16 with an
even larger diameter containing insulin with a concentration of 300
IU pr. ml.
[0059] FIGS. 3 to 5 show different configurations of adapters 1.
The adapter 1 of FIG. 3 is provided with two protrusions 9, 17 both
covering 360 degrees of the outer surface 6. The first protrusion 9
is shown as having a width W.
[0060] The adapter 1 shown in FIG. 4 is provided with a number of
protrusions 18 which are shaped as a number of raised points, and
which raised points are provided on a circle covering substantially
360 degrees of the outer surface 6 of the adapter 1.
[0061] The circular protrusion or protrusions can have a width W
that equals the longitudinal extension of the outer adapter surface
6 as shown in FIG. 5, in which case there in fact is no protrusions
but simply a relatively large diameter D of the entire outer
adapter surface 6.
[0062] The circular protrusion 9 shown in FIG. 3 is located in a
specific distance L from the distal end surface 4. Instead of
providing the circular protrusion 9 with different diameters, the
general idea of the present invention could also be realised by
providing the circular protrusion 9 in different distances L from
the distal end surface 4 for different insulin concentrations. It
is apparent that only one circular protrusion 9 is needed in this
case. The distance L could e.g. be chosen as a little distance for
an insulin with a concentration of 200 IU pr. ml. and a greater
distance for an insulin with a concentration of 100 IU pr. ml. The
cartridge receiving part 11, 12 of the medical delivery system
could then be made with an inside located neck or shoulder with a
narrow diameter preventing the cartridge 2 containing insulin with
a concentration on 200 IU pr. ml. to fully enter the cartridge
receiving part of a medical deliver system designed for insulin
with a concentration on 100 IU pr. ml.
[0063] Some preferred embodiments have been shown in the foregoing,
but it should be stressed that the invention is not limited to
these, but may be embodied in other ways within the subject matter
defined in the following claims.
* * * * *