U.S. patent application number 12/459661 was filed with the patent office on 2010-10-28 for binding molecules capable of neutralizing rabies virus and uses thereof. This patent application is currently assigned to Crucell Holland B.V.. Invention is credited to Alexander Berthold Hendrik Bakker, Cornelis Adriaan De Kruif, Robert Arjen Kramer, Willem Egbert Marissen.
Application Number | 20100272724 12/459661 |
Document ID | / |
Family ID | 34968690 |
Filed Date | 2010-10-28 |
United States Patent Application | 20100272724 |
Kind Code | A1 |
Bakker; Alexander Berthold Hendrik ; et al. | October 28, 2010 |
The invention provides binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. The invention further provides nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. Preferably, they can be used in the post-exposure prophylaxis of rabies.
Inventors: | Bakker; Alexander Berthold Hendrik; (Hillegom, NL) ; Marissen; Willem Egbert; (Woerden, NL) ; Kramer; Robert Arjen; (Utrecht, NL) ; De Kruif; Cornelis Adriaan; (De Bilt, NL) |
Correspondence Address: |
TRASKBRITT, P.C. P.O. BOX 2550 SALT LAKE CITY UT 84110 US |
Assignee: | Crucell Holland B.V. CN Leiden NL |
Family ID: | 34968690 |
Appl. No.: | 12/459661 |
Filed: | July 6, 2009 |
Application Number | Filing Date | Patent Number | ||
---|---|---|---|---|
11590126 | Oct 31, 2006 | 7579446 | ||
12459661 | ||||
PCT/EP05/52410 | May 26, 2005 | |||
11590126 | ||||
60575023 | May 27, 2004 | |||
Current U.S. Class: | 424/139.1 ; 435/320.1; 435/366; 435/5; 435/69.6; 530/387.9; 536/23.53 |
Current CPC Class: | C07K 16/10 20130101; A61K 2039/505 20130101; A61P 31/12 20180101; C07K 2317/34 20130101; A61K 2039/507 20130101; A61P 43/00 20180101; C07K 2317/622 20130101; A61P 31/14 20180101; C07K 2317/56 20130101; C12N 2760/20122 20130101; C07K 2317/21 20130101; G01N 33/56983 20130101; C07K 14/005 20130101; C07K 2317/76 20130101 |
Class at Publication: | 424/139.1 ; 536/23.53; 530/387.9; 435/320.1; 435/366; 435/69.6; 435/5 |
International Class: | A61K 39/395 20060101 A61K039/395; C07H 21/04 20060101 C07H021/04; C07K 16/00 20060101 C07K016/00; A61P 31/14 20060101 A61P031/14; C12N 15/63 20060101 C12N015/63; C12N 5/10 20060101 C12N005/10; C12P 21/00 20060101 C12P021/00; C12Q 1/70 20060101 C12Q001/70 |
Date | Code | Application Number |
---|---|---|
May 27, 2004 | EP | PCT/EP04/50943 |
Jul 29, 2004 | EP | PCT/EP04/51661 |
Sep 23, 2004 | EP | PCT/EP04/52286 |
Nov 3, 2004 | EP | PCT/EP04/52772 |
Jan 25, 2005 | EP | PCT/EP05/50310 |
Mar 3, 2005 | EP | PCT/EP05/50953 |
Sequence CWU 1
1
74819PRTArtificial sequenceCDR3 of SC04-001 1Gly Leu Tyr Gly Glu
Leu Phe Asp Tyr1 5211PRTArtificial sequenceCDR3 of SC04-004 2Asp
Tyr Leu Tyr Pro Thr Thr Asp Phe Asp Tyr1 5 10310PRTArtificial
sequenceCDR3 of SC04-008 3Met Gly Phe Thr Gly Thr Tyr Phe Asp Tyr1
5 10414PRTArtificial sequenceCDR3 of SC04-010 4Asp Gly Leu Asp Leu
Thr Gly Thr Ile Gln Pro Phe Gly Tyr1 5 10510PRTArtificial
sequenceCDR3 of SC04-018 5Val Ser Val Thr Thr Gly Ala Phe Asn Ile1
5 10610PRTArtificial sequenceCDR3 of SC04-021 6Gly Ser Val Leu Gly
Asp Ala Phe Asp Ile1 5 10712PRTArtificial sequenceCDR3 of SC04-026
7Thr Ser Asn Trp Asn Tyr Leu Asp Arg Phe Asp Pro1 5
10810PRTArtificial sequenceCDR3 of SC04-031 8Gly Ser Val Leu Gly
Asp Ala Phe Asp Ile1 5 10910PRTArtificial sequenceCDR3 of SC04-038
9Gly Ser Val Leu Gly Asp Ala Phe Asp Ile1 5 10109PRTArtificial
sequenceCDR3 of SC04-040 10Gly Ser Lys Val Gly Asp Phe Asp Tyr1
51120PRTArtificial sequenceCDR3 of SC04-060 11Glu Lys Glu Lys Tyr
Ser Asp Arg Ser Gly Tyr Ser Tyr Tyr Tyr Tyr1 5 10 15Tyr Met Asp Val
201214PRTArtificial sequenceCDR3 of SC04-073 12Asp Gly Leu Asp Leu
Thr Gly Thr Ile Gln Pro Phe Gly Tyr1 5 101312PRTArtificial
sequenceCDR3 of SC04-097 13Thr Ala Ser Asn Leu Gly Arg Gly Gly Met
Asp Val1 5 101410PRTArtificial sequenceCDR3 of SC04-098 14Val Ala
Val Ala Gly Thr His Phe Asp Tyr1 5 101510PRTArtificial sequenceCDR3
of SC04-103 15Val Ala Val Ala Gly Glu Ser Phe Asp Ser1 5
101612PRTArtificial sequenceCDR3 of SC04-104 16Ile Val Val Val Thr
Ala Leu Asp Ala Phe Asp Ile1 5 101711PRTArtificial sequenceCDR3 of
SC04-108 17Phe Met Ile Val Ala Asp Asp Ala Phe Asp Ile1 5
10189PRTArtificial sequenceCDR3 of SC04-120 18Gly Gly Lys Thr Gly
Glu Phe Asp Tyr1 51910PRTArtificial sequenceCDR3 of SC04-125 19Ile
Ala Thr Ala Gly Thr Gly Phe Asp Tyr1 5 102010PRTArtificial
sequenceCDR3 of SC04-126 20Met Gly Phe Thr Gly Thr Tyr Phe Asp Tyr1
5 102110PRTArtificial sequenceCDR3 of SC04-140 21Val Thr Asn Pro
Gly Asp Ala Phe Asp Ile1 5 10229PRTArtificial sequenceCDR3 of
SC04-144 22Gly Gly Lys Thr Gly Glu Phe Asp Tyr1 5239PRTArtificial
sequenceCDR3 of SC04-146 23Gly Gly Lys Thr Gly Glu Phe Asp Tyr1
52410PRTArtificial sequenceCDR3 of SC04-164 24Gly Ser Val Leu Gly
Asp Ala Phe Asp Ile1 5 102518PRTArtificial sequenceCDR3 of SO57
25Glu Asn Leu Asp Asn Ser Gly Thr Tyr Tyr Tyr Phe Ser Gly Trp Phe1
5 10 15Asp Pro26117PRTArtificial sequenceHeavy chain variable
region of SC04-001 26Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val
Val Arg Pro Gly Gly1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly
Phe Thr Phe Asp Asp Tyr 20 25 30Gly Met Ser Trp Val Arg Gln Ala Pro
Gly Lys Gly Leu Glu Trp Val 35 40 45Ser Gly Ile Asn Trp Asn Gly Gly
Ser Thr Gly Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser
Arg Asp Asn Ala Lys Asn Ser Leu Tyr65 70 75 80Leu Gln Met Asn Ser
Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Leu
Tyr Gly Glu Leu Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110Leu Val
Thr Val Ser 11527118PRTArtificial sequenceHeavy chain variable
region of SC04-004 27Glu Val Gln Leu Val Glu Ser Gly Gly Gly Leu
Val Gln Pro Gly Gly1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly
Phe Thr Phe Ser Asn Tyr 20 25 30Trp Met Asn Trp Val Arg Gln Ala Pro
Gly Lys Gly Leu Glu Trp Val 35 40 45Ser Ala Ile Ser Gly Ser Gly Gly
Ser Thr Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser
Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser
Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Asp Tyr
Leu Tyr Pro Thr Thr Asp Phe Asp Tyr Trp Gly Gln 100 105 110Gly Thr
Leu Val Thr Val 11528120PRTArtificial sequenceHeavy chain variable
region of SC04-008 28Gln Val Thr Leu Lys Glu Ser Gly Pro Thr Leu
Val Lys Pro Thr Gln1 5 10 15Thr Leu Thr Leu Thr Cys Thr Phe Ser Gly
Phe Ser Leu Ser Thr Ser 20 25 30Gly Val Gly Val Gly Trp Ile Arg Gln
Pro Pro Gly Lys Ala Leu Glu 35 40 45Trp Leu Ala Arg Ile Asp Trp Asp
Asp Asp Lys Tyr Tyr Ser Thr Ser 50 55 60Leu Lys Thr Arg Leu Thr Ile
Ser Lys Asp Thr Ser Lys Asn Gln Val65 70 75 80Val Leu Thr Met Thr
Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr 85 90 95Cys Ala Arg Met
Gly Phe Thr Gly Thr Tyr Phe Asp Tyr Trp Gly Gln 100 105 110Gly Thr
Leu Val Thr Val Ser Ser 115 12029123PRTArtificial sequenceHeavy
chain variable region of SC04-010 29Gln Val Gln Leu Val Gln Ser Gly
Gly Asp Leu Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala
Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg
Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Asp Ile Ser Tyr
Asp Gly Ser Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe
Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln
Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala
Lys Asp Gly Leu Asp Leu Thr Gly Thr Ile Gln Pro Phe Gly Tyr 100 105
110Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115
12030119PRTArtificial sequenceHeavy chain variable region of
SC04-018 30Glu Val Gln Leu Val Glu Ser Gly Pro Gly Leu Val Arg Pro
Ser Gly1 5 10 15Thr Leu Ser Leu Thr Cys Ala Val Ser Gly Gly Ser Ile
Ser Ser Ser 20 25 30Asn Trp Trp Ser Trp Val Arg Gln Pro Pro Gly Lys
Gly Leu Glu Trp 35 40 45Ile Gly Glu Ile Tyr His Ser Gly Ser Thr Asn
Tyr Asn Pro Ser Leu 50 55 60Lys Ser Arg Val Thr Ile Ser Val Asp Lys
Ser Lys Asn Gln Phe Ser65 70 75 80Leu Lys Leu Ser Ser Val Thr Ala
Ala Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Arg Val Ser Val Thr Thr
Gly Ala Phe Asn Ile Trp Gly Gln Gly 100 105 110Thr Met Val Thr Val
Ser Ser 11531119PRTArtificial sequenceHeavy chain variable region
of SC04-021 31Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln
Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu Glu Trp Val 35 40 45Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys
Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Ser Val Leu
Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 100 105 110Thr Met Val Thr
Val Ser Ser 11532121PRTArtificial sequenceHeavy chain variable
region of SC04-026 32Glu Val Gln Leu Val Glu Ser Gly Ala Glu Val
Lys Lys Pro Gly Glu1 5 10 15Ser Leu Lys Ile Ser Cys Lys Gly Ser Gly
Tyr Asn Phe Pro Tyr Ser 20 25 30Trp Ile Ala Trp Val Arg Gln Met Pro
Gly Lys Gly Leu Glu Trp Met 35 40 45Gly Ile Ile Phe Pro Gly Asp Ser
Asp Thr Arg Tyr Ser Pro Pro Phe 50 55 60Gln Gly Gln Val Thr Ile Ser
Ala Asp Asn Ser Lys Ser Thr Ala Tyr65 70 75 80Leu Gln Trp Ser Ser
Leu Lys Ala Ser Asp Thr Ala Met Tyr Tyr Cys 85 90 95Ala Arg Thr Ser
Asn Trp Asn Tyr Leu Asp Arg Phe Asp Pro Trp Gly 100 105 110Gln Gly
Thr Leu Val Thr Val Ser Ser 115 12033119PRTArtificial sequenceHeavy
chain variable region of SC04-031 33Glu Val Gln Leu Val Glu Ser Gly
Gly Gly Val Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala
Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg
Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Val Ile Ser Tyr
Asp Gly Ser Asn Lys Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe
Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln
Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala
Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 100 105
110Thr Met Val Thr Val Ser Ser 11534119PRTArtificial sequenceHeavy
chain variable region of SC04-038 34Gln Val Gln Leu Val Gln Ser Gly
Gly Gly Val Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala
Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg
Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Val Ile Ser Tyr
Asp Gly Ser Ser Lys Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe
Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln
Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala
Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile Trp Gly Gln Gly 100 105
110Thr Met Val Thr Val Ser Ser 11535118PRTArtificial sequenceHeavy
chain variable region of SC04-040 35Gln Val Gln Leu Val Gln Ser Gly
Gly Gly Val Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala
Ala Ser Gly Phe Thr Phe Gly Ser Tyr 20 25 30Gly Met His Trp Val Arg
Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Thr Ile Phe Tyr
Asp Gly Ser Tyr Lys Asp Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe
Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln
Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala
Lys Gly Ser Lys Val Gly Asp Phe Asp Tyr Trp Gly Gln Gly Thr 100 105
110Leu Val Thr Val Ser Ser 11536128PRTArtificial sequenceHeavy
chain variable region of SC04-060 36Gln Val Gln Leu Val Glu Ser Gly
Pro Gly Leu Val Lys Ala Ser Glu1 5 10 15Thr Leu Ser Leu Thr Cys Thr
Val Ser Asp Gly Ser Ile Ser Ser Phe 20 25 30Tyr Trp Ser Trp Ile Arg
Gln Pro Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Gly Glu Ile Gln Asp
Thr Gly Arg Thr Asn Tyr Asn Pro Ser Leu Lys 50 55 60Ser Arg Val Thr
Ile Ser Leu Asp Thr Ser Lys Asn Gln Phe Ser Leu65 70 75 80Thr Leu
Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr Tyr Cys Ala 85 90 95Arg
Glu Lys Glu Lys Tyr Ser Asp Arg Ser Gly Tyr Ser Tyr Tyr Tyr 100 105
110Tyr Tyr Met Asp Val Trp Gly Lys Gly Thr Thr Val Thr Val Ser Ser
115 120 12537123PRTArtificial sequenceHeavy chain variable region
of SC04-073 37Gln Val Gln Leu Val Gln Ser Gly Gly Gly Val Ala Gln
Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu Glu Trp Val 35 40 45Ala Asp Ile Ser Tyr Asp Gly Ser Asn Lys
Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Asp Gly Leu Asp
Leu Thr Gly Thr Ile Gln Pro Phe Gly Tyr 100 105 110Trp Gly Gln Gly
Thr Leu Val Thr Val Ser Ser 115 12038121PRTArtificial sequenceHeavy
chain variable region of SC04-097 38Glu Val Gln Leu Val Gln Ser Gly
Gly His Leu Val Gln Pro Gly Gly1 5 10 15Ser Leu Arg Leu Ser Cys Ala
Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Ala Met Ser Trp Val Arg
Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ser Leu Ile Ile Gly
Ser Gly Arg Ser Thr Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe
Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln
Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala
Lys Thr Ala Ser Asn Leu Gly Arg Gly Gly Met Asp Val Trp Gly 100 105
110Gln Gly Thr Thr Val Thr Val Ser Ser 115 12039119PRTArtificial
sequenceHeavy chain variable region of SC04-098 39Glu Val Gln Leu
Val Gln Ser Gly Gly Gly Ala Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg
Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met
His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala
Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe Tyr Ala Asp Ser Val 50 55
60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr Leu Tyr65
70 75 80Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr
Cys 85 90 95Ala Lys Val Ala Val Ala Gly Thr His Phe Asp Tyr Trp Gly
Gln Gly 100 105 110Thr Leu Val Thr Val Ser Ser
11540119PRTArtificial sequenceHeavy chain variable region of
SC04-103 40Gln Val Gln Leu Gln Glu Ser Gly Gly Gly Val Val Gln Pro
Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe
Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly
Leu Glu Trp Val 35 40 45Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Tyr
Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn
Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala
Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Val Ala Val Ala Gly
Glu Ser Phe Asp Ser Trp Gly Arg Gly 100 105 110Thr Leu Val Thr Val
Ser Ser 11541121PRTArtificial sequenceHeavy chain variable region
of SC04-104 41Gln Val Gln Leu Gln Glu Ser Gly Gly Gly Val Val Gln
Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu Glu Trp Val 35 40 45Ala Thr Ile Ser Tyr Asp Gly Asn Val Lys
Asp Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg
Thr Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Ile Val Val Val
Thr Ala Leu Asp Ala Phe Asp Ile Trp Gly 100
105 110Gln Gly Thr Met Val Thr Val Ser Ser 115
12042120PRTArtificial sequenceHeavy chain varaible region of
SC04-108 42Glu Val Gln Leu Val Gln Ser Gly Gly Gly Leu Val Gln Pro
Gly Gly1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe
Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly
Leu Glu Trp Val 35 40 45Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe
Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn
Ser Lys Asp Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala
Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Phe Met Ile Val Ala
Asp Asp Ala Phe Asp Ile Trp Gly Gln 100 105 110Gly Thr Met Val Thr
Val Ser Ser 115 12043118PRTArtificial sequenceHeavy chain variable
region of SC04-120 43Glu Val Gln Leu Val Gln Ser Gly Gly Gly Leu
Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly
Phe Thr Phe Ser Thr Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro
Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Thr Ile Ser Tyr Asp Gly Ser
Ile Lys Asp Tyr Ala Asp Ser Glu 50 55 60Lys Gly Arg Phe Thr Ile Ser
Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser
Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Gly
Lys Thr Gly Glu Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110Leu Val
Thr Val Ser Ser 11544119PRTArtificial sequenceHeavy chain variable
region of SC04-125 44Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val
Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly
Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro
Gly Lys Gly Leu Glu Trp Val 35 40 45Ala Val Ile Ser Tyr Asp Gly Ser
Asp Lys Tyr Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser
Arg Asp Asn Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser
Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Ile Ala
Thr Ala Gly Thr Gly Phe Asp Tyr Trp Gly Gln Gly 100 105 110Thr Leu
Val Thr Val Ser Ser 11545120PRTArtificial sequenceHeavy chain
variable region of SC04-126 45Gln Val Thr Leu Lys Glu Ser Gly Pro
Thr Leu Val Asn Pro Thr Gln1 5 10 15Thr Leu Thr Leu Thr Cys Thr Phe
Ser Gly Phe Ser Leu Ser Thr Gly 20 25 30Gly Val Gly Val Gly Trp Phe
Arg Gln Pro Pro Gly Lys Ala Leu Glu 35 40 45Trp Leu Ala Arg Ile Asp
Trp Asp Asp Asp Lys Tyr Tyr Ser Thr Ser 50 55 60Leu Lys Thr Arg Leu
Thr Ile Ser Lys Asp Thr Ser Lys Ile Gln Val65 70 75 80Val Leu Thr
Met Thr Asn Met Asp Pro Val Asp Thr Ala Thr Tyr Tyr 85 90 95Cys Ala
Arg Met Gly Phe Thr Gly Thr Tyr Phe Asp Tyr Trp Gly Gln 100 105
110Gly Thr Leu Val Thr Val Ser Ser 115 12046119PRTArtificial
sequenceHeavy chain variable region of SC04-140 46Gln Met Gln Leu
Val Gln Ser Gly Gly Gly Val Val Gln Pro Gly Arg1 5 10 15Ser Leu Arg
Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25 30Gly Met
His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val 35 40 45Ala
Val Ile Leu Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala Asp Ser Val 50 55
60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Ala Leu Tyr65
70 75 80Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val Tyr Tyr
Cys 85 90 95Ala Lys Val Thr Asn Pro Gly Asp Ala Phe Asp Ile Trp Gly
Gln Gly 100 105 110Thr Met Val Thr Val Ser Ser
11547118PRTArtificial sequenceHeavy chain variable region of
SC04-144 47Gln Val Gln Leu Gln Glu Leu Gly Gly Gly Val Val Gln Pro
Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe
Gly Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly
Leu Glu Trp Val 35 40 45Ala Thr Ile Ser Tyr Asp Gly Ser Ile Lys Asp
Tyr Ala Asp Ser Glu 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn
Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala
Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Gly Lys Thr Gly
Glu Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110Leu Val Thr Val Ser
Ser 11548118PRTArtificial sequenceHeavy chain variable region of
SC04-146 48Glu Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln Pro
Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe
Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly
Leu Glu Trp Val 35 40 45Ala Thr Ile Ser Tyr Asp Gly Ser Ile Lys Asp
Tyr Ala Asp Ser Glu 50 55 60Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn
Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala
Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Gly Lys Thr Gly
Glu Phe Asp Tyr Trp Gly Gln Gly Thr 100 105 110Leu Val Thr Val Ser
Ser 11549119PRTArtificial sequenceHeavy chain variable region of
SC04-164 49Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln Pro
Gly Arg1 5 10 15Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe
Ser Ser Tyr 20 25 30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly
Leu Glu Trp Val 35 40 45Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys Tyr
Tyr Ala Asp Ser Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn
Ser Lys Asn Thr Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala
Glu Asp Thr Ala Val Tyr Tyr Cys 85 90 95Ala Lys Gly Ser Val Leu Gly
Asp Ala Phe Asp Ile Trp Gly Gln Gly 100 105 110Thr Met Val Thr Val
Ser Ser 11550108PRTArtificial sequenceLight chain variable region
of SC04-001 50Ser Ser Glu Leu Thr Gln Asp Pro Ala Val Ser Val Ala
Leu Gly Gln1 5 10 15Thr Val Arg Ile Thr Cys Gln Gly Asp Ser Leu Arg
Ser Tyr Tyr Ala 20 25 30Ser Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro
Val Leu Val Ile Tyr 35 40 45Gly Lys Asn Asn Arg Pro Ser Gly Ile Pro
Asp Arg Phe Ser Gly Ser 50 55 60Ser Ser Gly Asn Thr Ala Ser Leu Thr
Ile Thr Gly Ala Gln Ala Glu65 70 75 80Asp Glu Ala Asp Tyr Tyr Cys
Asn Ser Arg Asp Ser Ser Gly Asn His 85 90 95Val Val Phe Gly Gly Gly
Thr Lys Leu Thr Val Leu 100 10551103PRTArtificial sequenceLight
chain variable region of SC04-004 51Thr Gln Ser Pro Ser Ser Leu Ser
Ala Ser Val Gly Asp Arg Val Thr1 5 10 15Ile Thr Cys Arg Ala Ser Gln
Ser Ile Ser Ser Tyr Leu Asn Trp Tyr 20 25 30Gln Gln Lys Pro Gly Lys
Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser 35 40 45Ser Leu Gln Ser Gly
Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly 50 55 60Thr Asp Phe Thr
Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala65 70 75 80Thr Tyr
Tyr Cys Gln Gln Ser Tyr Ser Thr Pro Pro Thr Phe Gly Gln 85 90 95Gly
Thr Lys Val Glu Ile Lys 10052109PRTArtificial sequenceLight chain
variable region of SC04-008 52Gln Ala Val Leu Thr Gln Pro Ser Ser
Val Ser Val Ala Pro Gly Glu1 5 10 15Thr Ala Ser Val Thr Cys Gly Gly
Asp Asn Ile Gly Ser Lys Ser Val 20 25 30His Trp Tyr Gln Lys Lys Pro
Gly Gln Ala Pro Val Leu Val Val Phe 35 40 45Asp Asp Ser Asp Arg Pro
Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser 50 55 60Thr Ser Gly Asn Thr
Ala Ala Leu Thr Ile Ser Arg Val Glu Ala Gly65 70 75 80Asp Glu Ala
Asp Tyr Tyr Cys Gln Val Trp Asp Ser Ser Asn Asp His 85 90 95Leu Tyr
Val Phe Gly Pro Gly Thr Gln Leu Thr Val Leu 100
10553107PRTArtificial sequenceLight chain variable region of
SC04-010 53Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Arg Asn Asp 20 25 30Leu Gly Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys
Leu Gln Asp Tyr Asn Tyr Pro Arg 85 90 95Thr Phe Gly Gln Gly Thr Lys
Val Glu Ile Lys 100 10554110PRTArtificial sequenceLight chain
variable region of SC04-018 54Gln Pro Val Leu Thr Gln Pro Leu Ser
Ala Ser Gly Thr Pro Gly Gln1 5 10 15Arg Val Thr Ile Ser Cys Ser Gly
Asp Thr Ser Asn Ile Gly Ser Asn 20 25 30Thr Val His Trp Tyr Gln Arg
Leu Pro Gly Thr Ala Pro Lys Leu Leu 35 40 45Ile His Asn Asn Asn Gln
Arg Pro Ser Gly Val Pro Asp Arg Phe Ser 50 55 60Gly Ala Lys Ser Gly
Thr Ser Ala Ser Leu Ala Ile Ser Gly Leu Gln65 70 75 80Ser Glu Asp
Glu Ala Asp Tyr Phe Cys Ala Ala Trp Asp Asp Asn Leu 85 90 95Asn Gly
Tyr Val Phe Gly Thr Gly Thr Lys Val Thr Val Leu 100 105
11055107PRTArtificial sequenceLight chain variable region of
SC04-021 55Asp Ile Gln Met Thr Gln Ser Pro Phe Ser Leu Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Gly Ser Ser 20 25 30Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Phe Cys
Leu Gln His His Asp Tyr Pro Leu 85 90 95Thr Phe Gly Gly Gly Thr Lys
Leu Glu Ile Lys 100 10556112PRTArtificial sequenceLight chain
variable region of SC04-026 56Asp Val Val Met Thr Gln Ser Pro Leu
Ser Leu Pro Val Thr Pro Gly1 5 10 15Glu Pro Ala Ser Ile Ser Cys Arg
Ser Ser Gln Ser Leu Leu His Ser 20 25 30Asn Gly His Asp Tyr Leu Asp
Trp Tyr Val Gln Lys Pro Gly Gln Ser 35 40 45Pro Gln Pro Leu Ile Tyr
Leu Gly Ser Asp Arg Ala Ser Gly Val Pro 50 55 60Asp Arg Phe Ser Gly
Ser Gly Ser Gly Thr His Phe Thr Leu Asn Ile65 70 75 80Ser Arg Val
Glu Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln Ser 85 90 95Leu Gln
Thr Pro Trp Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 105
11057107PRTArtificial sequenceLight chain variable region of
SC04-031 57Asp Ile Gln Met Thr Gln Ser Pro Ser Phe Val Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Ser Ser Trp 20 25 30Leu Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys
Gln Gln Ala Asn Ser Phe Pro Leu 85 90 95Thr Phe Gly Gly Gly Thr Lys
Val Glu Ile Lys 100 10558107PRTArtificial sequenceLight chain
variable region of SC04-038 58Asp Ile Gln Leu Thr Gln Ser Pro Ser
Ser Val Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg
Ala Ser Gln Gly Ile Ser Gly Trp 20 25 30Leu Ala Trp Tyr Gln Gln Lys
Pro Glu Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu
Gln Arg Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe
Ala Thr Tyr Tyr Cys Gln Gln Ala Asn Ser Phe Pro Pro 85 90 95Thr Phe
Gly Gln Gly Thr Arg Leu Glu Ile Lys 100 10559108PRTArtificial
sequenceLight chain variable region of SC04-040 59Gln Pro Val Leu
Thr Gln Pro Pro Ser Val Ser Val Ala Pro Gly Gln1 5 10 15Thr Ala Arg
Ile Ser Cys Gly Gly Asp Asn Ile Gly Thr Asn Thr Val 20 25 30Gln Trp
Tyr Gln Gln Lys Pro Gly Gln Ala Pro Val Leu Val Val Tyr 35 40 45Asp
Asp Ser Asp Arg Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser 50 55
60Asn Ser Gly Asp Thr Ala Thr Leu Thr Ile Ser Arg Val Glu Ala Gly65
70 75 80Asp Glu Ala Asp Tyr Tyr Cys Gln Val Trp Asp Asp Ser Ser Asp
Leu 85 90 95Val Val Phe Gly Gly Gly Thr Lys Val Thr Val Leu 100
10560107PRTArtificial sequenceLight chain variable region of
SC04-060 60Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Ser Thr Tyr 20 25 30Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Asn Leu Leu Ile 35 40 45Tyr Gly Ala Ser Asn Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Glu Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys
Gln Gln Ser Phe Thr Thr Pro Arg 85 90 95Thr Phe Gly Gln Gly Thr Lys
Leu Glu Ile Lys 100 10561107PRTArtificial sequenceLight chain
variable region of SC04-073 61Asp Ile Gln Leu Thr Gln Ser Pro Ser
Phe Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg
Ala Ser His Ser Ile Ser Ser Trp 20 25 30Leu Ala Trp Tyr Gln Gln Lys
Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Lys Ala Ser Ser Leu
Glu Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe
Ala Thr Tyr Tyr Cys Leu Gln Asp Tyr Asn Tyr Pro Arg 85 90 95Thr Phe
Gly Gln Gly Thr Lys Leu Glu Ile Lys 100 10562107PRTArtificial
sequenceLight chain variable region of SC04-097 62Asp Ile Gln Leu
Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val
Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Ser Ser His 20 25 30Leu
Ala Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40
45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly
50 55 60Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln
Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Phe Asn Ser
Tyr Pro Ile 85 90 95Thr Phe Gly Gln Gly Thr Arg Leu Glu Ile Lys 100
10563107PRTArtificial sequenceLight chain variable region of
SC04-098 63Asp Ile Gln Met Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Arg Asn Asp 20 25 30Leu Gly Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys
Gln Gln Leu Asn Ser Tyr Pro Pro 85 90 95Thr Phe Gly Gly Gly Thr Lys
Val Glu Ile Lys 100 10564107PRTArtificial sequenceLight chain
variable region of SC04-103 64Asp Ile Gln Leu Thr Gln Ser Pro Ser
Ser Val Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg
Ala Ser Gln Gly Ile Ser Ser Trp 20 25 30Leu Ala Trp Tyr Gln Gln Lys
Pro Gly Lys Ala Pro Arg Ser Leu Ile 35 40 45Tyr Asp Ala Ser Ser Leu
Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe
Ala Thr Tyr Tyr Cys Gln Gln Ala Asp Ser Phe Pro Ile 85 90 95Thr Phe
Gly Gln Gly Thr Arg Leu Glu Ile Lys 100 10565109PRTArtificial
sequenceLight chain variable region of SC04-104 65Asp Ile Gln Leu
Thr Gln Ser Pro Ser Thr Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val
Thr Ile Thr Cys Arg Ala Ser Gln Ile Leu Gly His Trp 20 25 30Leu Pro
Leu Ser Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu 35 40 45Leu
Ile Ser Lys Ala Ser Ser Leu Glu Ser Gly Val Pro Pro Arg Phe 50 55
60Ser Gly Ser Gly Ser Gly Ser Asp Phe Thr Leu Thr Ile Ser Ser Leu65
70 75 80Gln Pro Asp Asp Phe Ala Thr Tyr Tyr Cys Leu Gln Tyr His Glu
Tyr 85 90 95Pro Leu Thr Phe Gly Gly Gly Thr Lys Leu Glu Ile Lys 100
10566107PRTArtificial sequenceLight chain variable region of
SC04-108 66Asp Ile Gln Leu Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser
Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile
Ser Ser His 20 25 30Leu Val Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Ser Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly 50 55 60Ser Glu Ser Ala Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe Ala Thr Tyr Tyr Cys
Gln Gln Tyr Tyr Ser Tyr Pro Ile 85 90 95Thr Phe Gly Gln Gly Thr Arg
Leu Glu Ile Lys 100 10567107PRTArtificial sequenceLight chain
variable region of SC04-120 67Asp Ile Gln Leu Thr Gln Ser Pro Ser
Thr Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg
Ala Ser Gln Gly Ile Asn Ser Tyr 20 25 30Leu Ala Trp Tyr Gln Gln Glu
Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Thr Leu
Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr
Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe
Ala Thr Tyr Tyr Cys Gln Gln Leu Asn Ser Tyr Pro Phe 85 90 95Thr Phe
Gly Pro Gly Thr Lys Val Asp Ile Lys 100 10568107PRTArtificial
sequenceLight chain variable region of SC04-125 68Asp Ile Gln Met
Thr Gln Ser Pro Ser Ser Val Ser Ala Ser Val Gly1 5 10 15Asp Arg Val
Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Ser Ser Tyr 20 25 30Leu Ala
Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr
Asp Ala Ser Ser Leu Glu Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55
60Ser Gly Ser Gly Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65
70 75 80Asp Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Leu Asn Ser Tyr Pro
Leu 85 90 95Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100
10569109PRTArtificial sequenceLight chain variable region of
SC04-126 69Gln Ser Val Leu Thr Gln Pro Pro Ser Val Ser Val Ala Pro
Gly Lys1 5 10 15Thr Ala Arg Ile Thr Cys Gly Gly Asn Asn Ile Gly Ser
Lys Ser Val 20 25 30His Trp Tyr Gln Gln Lys Pro Gly Gln Ala Pro Val
Leu Val Ile Tyr 35 40 45Tyr Asp Ser Asp Arg Pro Ser Gly Ile Pro Glu
Arg Phe Ser Gly Ser 50 55 60Asn Ser Gly Asn Thr Ala Thr Leu Thr Ile
Ser Arg Val Glu Ala Gly65 70 75 80Asp Glu Ala Asp Tyr Tyr Cys Gln
Val Trp Asp Ser Ser Ser Asp His 85 90 95Pro Tyr Val Phe Gly Thr Gly
Thr Lys Leu Thr Val Leu 100 10570107PRTArtificial sequenceLight
chain variable region of SC04-140 70Asp Ile Gln Met Thr Gln Ser Pro
Ser Ser Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys
Arg Ala Ser Gln Gly Ile Ser Ser Ala 20 25 30Leu Ala Trp Tyr Gln Gln
Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Asp Ala Ser Ser
Leu Glu Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly
Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp
Phe Ala Thr Tyr Tyr Cys Gln Gln Phe Asn Ser Tyr Pro Leu 85 90 95Thr
Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100 10571107PRTArtificial
sequenceLight chain variable region of SC04-144 71Asp Ile Gln Leu
Thr Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val
Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Ser Ser Tyr 20 25 30Leu Ala
Trp Tyr Gln Gln Lys Pro Gly Lys Gly Pro Lys Leu Leu Ile 35 40 45Tyr
Ala Ala Ser Thr Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55
60Ser Gly Ser Gly Thr Asp Phe Ser Leu Thr Ile Ser Ser Leu Gln Pro65
70 75 80Glu Asp Leu Ala Thr Tyr Tyr Cys Gln Gln Tyr Asp Ser Tyr Pro
Leu 85 90 95Thr Phe Gly Gly Gly Thr Lys Val Glu Ile Lys 100
10572107PRTArtificial sequenceLight chain variable region of
SC04-146 72Asp Val Val Met Thr Gln Ser Pro Ala Thr Leu Ser Val Ser
Pro Gly1 5 10 15Glu Ser Ala Thr Leu Phe Cys Arg Ala Ser Glu Ser Val
Tyr Ser Asn 20 25 30Leu Ala Trp Tyr Gln His Lys Pro Gly Arg Ala Pro
Arg Leu Leu Ile 35 40 45Tyr Gly Ala Ser Thr Arg Ala Thr Gly Ile Pro
Ala Arg Phe Asp Gly 50 55 60Thr Gly Ser Gly Thr Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Ser65 70 75 80Glu Asp Phe Ala Val Tyr Tyr Cys
Gln Gln Tyr Asn Asp Trp Pro Ile 85 90 95Thr Phe Gly Gln Gly Thr Arg
Leu Glu Ile Lys 100 10573107PRTArtificial sequenceLight chain
variable region of SC04-164 73Asp Ile Gln Leu Thr Gln Ser Pro Ser
Ser Val Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys Arg
Ala Ser Gln Gly Ile Ser Ser Trp 20 25 30Leu Ala Trp Tyr Gln Gln Lys
Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser Leu
Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly Thr
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp Phe
Ala Thr Tyr Tyr Cys Gln Gln Ala Asn Ser Phe Pro Leu 85 90 95Thr Phe
Gly Gly Gly Thr Lys Val Asp Ile Lys 100 10574351DNAArtificial
sequenceHeavy chain variable region SC04-001 74gaggtgcagc
tggtggagtc tgggggaggt gtggtacggc ctggggggtc cctgagactc 60tcctgtgcag
cctctggatt cacctttgat gattatggca tgagctgggt ccgccaagct
120ccagggaagg ggctggagtg ggtctctggt attaattgga atggtggtag
cacaggttat 180gcagactctg tgaagggccg attcaccatc tccagagaca
acgccaagaa ctccctgtat 240ctgcaaatga acagtctgag agccgaggac
acggccgtgt attactgtgc aaagggcctt 300tatggggagc tttttgacta
ctggggccaa ggtaccctgg tcaccgtctc g 35175354DNAArtificial
sequenceHeavy chain variable region of SC04-004 75gaggtgcagc
tggtggagtc tgggggaggc ttggtccagc ctggggggtc cctgagactc 60tcctgtgcag
cctctggatt caccttcagc aactactgga tgaactgggt ccgccaggcg
120cccgggaagg ggctggagtg ggtctcagct attagtggta gtggtggtag
cacatactac 180gcagactccg tgaagggccg gttcaccatc tccagagaca
attccaagaa cacgctgtat 240ctgcaaatga acagcctgag agccgaggac
acggctgtgt attactgtgc caaagactac 300ctctacccca ccaccgactt
cgattactgg ggccagggca ccctggtgac cgtg 35476360DNAArtificial
sequenceHeavy chain varaible region of SC04-008 76caggtcacct
tgaaggagtc tggtcctacg ctggtgaaac ccacacagac cctcacgctg 60acctgcacct
tctctgggtt ctcactcagc actagtggag tgggtgtggg ctggatccgt
120cagcccccag gaaaggccct ggagtggctt gcacgcattg attgggatga
tgataaatac 180tacagcacat ctctgaagac caggctcacc atctccaagg
acacctccaa aaaccaggtg 240gtccttacaa tgaccaacat ggaccctgtg
gacacagcca cgtattactg tgcacggatg 300ggtttcactg gaacctactt
tgactactgg ggccagggca ccctggtcac cgtctcgagc 36077369DNAArtificial
sequenceHeavy chain variable region of SC04-010 77caggtgcagc
tggtgcagtc tgggggagac ttggtccagc ctgggaggtc cctgagactc 60tcctgtgcag
cctctggatt caccttcagt agctatggca tgcactgggt ccgccaggct
120ccaggcaagg ggctggagtg ggtggcagat atatcatatg atggaagtaa
taaatactat 180gcagactccg tgaagggccg attcaccatt tccagagaca
attccaagaa cacgctgtat 240ctgcaaatga acagcctgag agctgaggac
acggctgtgt attactgtgc gaaagatggg 300ctggatttaa ctggaacgat
tcagccattt ggctactggg gccagggaac cctggtcacc 360gtctcgagc
36978357DNAArtificial sequenceHeavy chain variable region of
SC04-018 78gaggtgcagc tggtggagtc tggcccagga ctggtgaggc cttcggggac
cctgtccctc 60acctgcgctg tctctggtgg ctccatcagc agtagtaact ggtggagttg
ggtccgccag 120cccccaggga aggggctgga gtggattggg gaaatctatc
atagtgggag caccaactac 180aacccgtccc tcaagagtcg agtcaccata
tcagtagaca agtccaagaa ccagttctcc 240ctgaagctga gctctgtgac
cgccgcggac acggccgtgt attactgtgc gagagtttct 300gtgactacgg
gtgcttttaa tatctggggc caagggacaa tggtcaccgt ctcgagc
35779357DNAArtificial sequenceHeavy chain varaible region SC04-021
79gaggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc
60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt ccgccaggct
120ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagtag
taaatattat 180gcagactccg tgaagggccg attcaccatc tccagagaca
attccaagaa cacgctgtat 240ctgcaaatga acagcctgag agctgaggac
acggctgtgt attactgtgc gaaagggtcc 300gtcctcggtg atgcttttga
tatctggggc caagggacaa tggtcaccgt ctcgagc 35780363DNAArtificial
sequenceHeavy chain variable region of SC04-026 80gaggtgcagc
tggtggagtc tggagcagag gtgaagaagc cgggggaatc tctgaagatc 60tcctgtaagg
gttctggata caactttccc tactcctgga tcgcctgggt gcgccagatg
120cccgggaaag gcctggagtg gatggggatc atctttcctg gtgactctga
caccagatat 180agtccgccct tccaaggcca ggtcaccatc tcagccgaca
actccaaaag caccgcctac 240ctgcagtgga gtagcctgaa ggcctcggac
accgccatgt attactgtgc gcggacctcg 300aactggaact atttggaccg
gttcgacccc tggggccagg gcaccctggt caccgtctcg 360agc
36381357DNAArtificial sequenceHeavy chain varaible region of
SC04-031 81gaggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atatcatatg
atggaagtaa taaatactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggtcc 300gtcctcggtg
atgcttttga tatctggggc caagggacaa tggtcaccgt ctcgagc
35782357DNAArtificial sequenceHeavy chain varaible region of
SC04-038 82caggtgcagc tggtgcaatc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atatcatatg
atggaagtag taaatattat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggtcc 300gtcctcggtg
atgcttttga tatctggggc caagggacaa tggtcaccgt ctcgagc
35783354DNAArtificial sequenceHeavy chain variable region of
SC04-040 83caggtgcagc tggtgcagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcggt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcaact atattctatg
atggaagtta taaagactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaaggcagt 300aaggtaggcg
actttgacta ctggggccag ggaaccctgg tcaccgtctc gagc
35484384DNAArtificial sequenceHeavy chain variable region of
SC04-060 84caggtgcagc tggtggagtc tggcccagga ctggtgaagg cttcggagac
cctgtccctc 60acttgcacgg tctctgatgg ctccatcagt agtttctact ggagctggat
ccggcagccc 120cccgggaagg gactggagtg ggttggggaa atccaggaca
ctgggaggac caattacaac 180ccctccctca agagtcgagt cactatatca
ctagacacgt ccaagaacca gttctccctg 240acgttgagct ctgtgaccgc
tgcggacacg gccgtgtatt actgcgcgag agagaaggag 300aaatactctg
atagaagcgg ttattcgtac tactactatt acatggacgt ctggggcaaa
360gggaccacgg tcaccgtctc gagc 38485369DNAArtificial sequenceHeavy
chain variable region of SC04-073 85caggtgcagc tggtgcagtc
tgggggaggc gtggcccagc ctgggaggtc cctgagactc 60tcctgtgcag cgtctggatt
caccttcagt agttatggca tgcactgggt ccgccaggct 120ccaggcaagg
ggctggagtg ggtggcagat atatcatatg atggaagtaa taaatactat
180gcagactccg tgaagggccg attcaccatt tccagagaca attccaagaa
cacgctgtat 240ctgcaaatga acagcctgag agctgaggac acggctgtgt
attactgtgc gaaagatggg 300ctggatttaa ctggaacgat tcagccattt
ggctactggg gccagggcac cctggtcacc 360gtctcgagc 36986369DNAArtificial
sequenceHeavy chain variable region of SC04-097 86caggtgcagc
tggtgcagtc tgggggagac ttggtccagc ctgggaggtc cctgagactc 60tcctgtgcag
cctctggatt caccttcagt agctatggca tgcactgggt ccgccaggct
120ccaggcaagg ggctggagtg ggtggcagat atatcatatg atggaagtaa
taaatactat 180gcagactccg tgaagggccg attcaccatt tccagagaca
attccaagaa cacgctgtat 240ctgcaaatga acagcctgag agctgaggac
acggctgtgt attactgtgc gaaagatggg 300ctggatttaa ctggaacgat
tcagccattt ggctactggg gccagggaac cctggtcacc 360gtctcgagc
36987357DNAArtificial sequenceHeavy chain variable region of
SC04-098 87gaagtgcagc tggtgcagtc tgggggaggc gcggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggctgtt atattatatg
atggaagtga taaattctat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcagatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagtagca 300gtggctggta
cgcactttga ctactggggc cagggaaccc tggtcaccgt ctcgagc
35788357DNAArtificial sequenceHeavy chain variable region of
SC04-103 88caggtgcagc tgcaggagtc ggggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atattatatg
atggaagtga taaatactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagtcgct 300gtggctgggg
aaagctttga ctcctggggc cggggcaccc tggtcaccgt ctcgagc
35789363DNAArtificial sequenceHeavy chain variable region of
SC04-104 89caggtgcagc tgcaggagtc ggggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcaact atatcatatg
atggaaatgt taaagactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca
attccaagaa cacgctgtat 240ctgcaaatga acagcctgag aactgaggac
acggctgtgt attactgtgc gaaaatagtg 300gtggtgaccg ccctcgatgc
ttttgatatc tggggccaag ggacaatggt caccgtctcg 360agc
36390360DNAArtificial sequenceHeavy chain varaible region of
SC04-108 90gaagtgcagc tggtgcagtc tgggggaggc ttggtacagc ctggggggtc
cctgagactc 60tcctgtgcag cgtctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atattatatg
atggaagtga taagttctat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagga cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaatttatg 300atagtagcag
atgatgcttt tgatatctgg ggccaaggga caatggtcac cgtctcgagc
36091354DNAArtificial sequenceHeavy chain variable region of
SC04-120 91gaggtgcagc tggtgcagtc tgggggaggc ttggtacagc ctggcaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt acctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcaact atatcatatg
atggaagtat taaagactat 180gcagactccg agaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggggg 300aagactggag
agtttgacta ctggggccag ggaaccctgg tcaccgtctc gagc
35492357DNAArtificial sequenceHeavy chain variable region of
SC04-125 92caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atatcatatg
atggaagtga taaatactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctctat 240ctgcaaatga acagcttgag
agctgaggac acggctgtgt attactgtgc gaagatagca 300acagctggta
ccgggtttga ctactggggc cagggaaccc tggtcaccgt ctcgagc
35793360DNAArtificial sequenceHeavy chain variable region of
SC04-126 93caggtcacct tgaaggagtc tggtcccacg ctggtgaacc ccacacagac
cctcacgttg 60acctgcacct tctctgggtt ctcgctcagc actggtggag tgggtgtggg
ctggttccgt 120cagcccccag ggaaggccct ggagtggctt gcacgcattg
attgggatga tgataaatac 180tacagcacat ctctgaagac caggctcacc
atctccaagg acacctccaa aatccaggtg 240gtccttacaa tgaccaacat
ggaccctgtg gacacagcca cgtattactg tgcacggatg 300ggtttcactg
gaacctactt tgactactgg ggccagggca ccctggtcac cgtctcgagc
36094357DNAArtificial sequenceHeavy chain variable region of
SC04-140 94cagatgcagc tggtgcagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atattatatg
atggaagtaa taaatactat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cgcgttgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaggtgacc 300aaccccggag
atgcttttga tatctggggc caagggacca tggtcaccgt ctcgagc
35795354DNAArtificial sequenceHeavy chain variable region of
SC04-144 95caggtgcagc tgcaggagtt ggggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcggt agctatggca tgcactgggt
ccgccaggct 120ccgggcaagg ggctggagtg ggtggcaact atatcatatg
atggaagtat taaagactat 180gcagactccg agaagggccg attcaccatc
tccagagaca attccaagaa cacactgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggggg 300aagactggag
agtttgacta ctggggccag ggaaccctgg tcaccgtctc gagc
35496354DNAArtificial sequenceHeavy chain variable region of
SC04-146 96gaagtgcagc tggtgcagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccgggcaagg ggctggagtg ggtggcaact atatcatatg
atggaagtat taaagactat 180gcagactccg aggagggccg attcaccatc
tccagagaca attccaagaa cacactgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggggg 300aagactggag
agtttgacta ctggggccag ggcaccctgg tcaccgtctc gagc
35497357DNAArtificial sequenceHeavy chain variable region of
SC04-164 97gaggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggcagtt atatcatatg
atggaagcag taaatactac 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcaaatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagggtcc 300gtcctcggtg
atgcttttga tatctggggc caagggacaa tggtcaccgt ctcgagc
35798324DNAArtificial sequenceLight chain varaible region of
SC04-001 98tcgtctgagc tgactcagga ccctgctgtg tctgtggcct tgggacagac
agtcaggatc 60acatgccaag gagacagcct cagaagctat tatgcaagct ggtaccagca
gaagccagga 120caggcccctg tacttgtcat ctatggtaaa aacaaccggc
cctcagggat cccagaccga 180ttctctggct ccagctcagg aaacacagct
tccttgacca tcactggggc tcaggcggaa 240gatgaggctg actattactg
taactcccgg gacagcagtg gtaaccatgt ggtattcggc 300ggagggacca
agctgaccgt ccta 32499309DNAArtificial sequenceLight chain variable
region of SC04-004 99acccagtctc catcctccct gtctgcatct gtaggagaca
gagtcaccat cacttgccgg 60gcaagtcaga gcattagcag ctacttaaat tggtatcagc
agaaaccagg gaaagcccct 120aagctcctga tctatgctgc atccagtttg
caaagtgggg tcccatcaag gttcagtggc 180agtggatctg ggacagattt
cactctcacc atcagcagtc tgcaacctga agattttgca 240acttactact
gtcaacagag ttacagtacc cctccaacgt tcggccaagg gaccaaggtg 300gagatcaaa
309100327DNAArtificial sequenceLight chain variable region of
SC04-008 100caggctgtgc tgactcagcc gtcctcggtg tcagtggccc caggagagac
ggccagcgtt 60acctgtgggg gagacaacat tgggagtaag agtgtgcact ggtaccaaaa
gaagccaggc 120caggcccctg tgctggtcgt ctttgatgat agcgaccggc
cctcagggat ccctgagcga 180ttctctggct ccacctctgg gaacacggcc
gccctgacca tcagcagggt cgaagccggg 240gatgaggccg actattactg
tcaggtgtgg gatagtagta atgatcatct ttatgtcttc 300ggacccggga
cccagctcac cgtttta 327101321DNAArtificial sequenceLight chain
variable region of SC04-010 101gacatccaga tgacccagtc tccatcctcc
ctgtctgcat ctgtaggaga cagagtcacc 60atcacttgcc gggcaagtca gggcattaga
aatgatttag gctggtatca gcagaaacca 120gggaaagccc ctaagctcct
gatctatgct gcatccagtt tacaaagtgg ggtcccatca 180aggttcagcg
gcagtggatc tggcacagat ttcactctca ccatcagcag cctgcagcct
240gaagattttg caacttatta ctgtctacaa gattacaatt accctcggac
gttcggccaa 300gggaccaagg tggagatcaa a 321102330DNAArtificial
sequenceLight chain variable region of SC04-018 102cagcctgtgc
tgactcagcc cctctcagcg tctgggaccc ccgggcagag ggtcaccatc 60tcttgttctg
gagacacctc caacatcgga agtaatactg tacactggta ccagcgcctc
120ccaggaacgg cccccaaact cctcatccat aataataatc agcggccctc
aggggtccct 180gaccggttct ctggcgccaa gtctggcacc tcagcctccc
tggccatcag tgggctccag 240tctgaggatg aggctgatta tttctgtgca
gcatgggatg acaacctgaa tggttatgtc 300ttcggaactg ggaccaaggt
caccgtccta 330103321DNAArtificial sequenceLight chain variablre
region of SC04-021 103gacatccaga tgacccagtc tccattctcc ctgtctgctt
ctgtcggaga cagagttacc 60atcacttgcc gggccagtca gggcattggc agttccttag
cctggtatca gcaaaaacca 120gggaaagccc ctaaactcct gatctacgct
gcatccagtt tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagat ttcactctca ccatcagcag cctgcagcct 240gaagattttg
caacttattt ctgtctgcag catcatgatt acccgctcac tttcggcgga
300gggaccaagc tggagatcaa a 321104336DNAArtificial sequenceLight
chain variable region of SC04-026 104gatgttgtga tgactcagtc
tccactctcc ctgcccgtca cccctggaga gccggcctcc 60atctcctgca ggtctagtca
gagcctcctg catagtaatg gacatgatta cttggattgg 120tacgtgcaga
agccagggca gtctccacag cccctgatct atttgggttc tgatcgggcc
180tccggggtcc ctgacaggtt cagtggcagt ggatcaggca cacattttac
actgaatatc 240agcagagtgg aggctgagga tgttggggtt tattactgca
tgcaatctct acaaactcct 300tggacttttg gccaggggac caagctggag atcaaa
336105321DNAArtificial sequenceLight chain variable region of
SC04-031 105gacatccaga tgacccagtc tccatctttc gtgtctgcat ctgtaggaga
cagagtcacc 60atcacttgtc gggcgagtca gggtattagc agttggttag cctggtatca
gcagaaacca 120gggaaagccc ctaagctcct gatctatgct gcatccagtt
tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc tgggacagat
ttcactctca ccatcagcag cctgcagcct 240gaagattttg caacttacta
ttgtcaacag gctaacagtt tcccactcac tttcggcgga 300gggaccaagg
tggagatcaa a 321106321DNAArtificial sequenceLight chain variable
region of SC04-038 106gacatccagt tgactcagtc tccatcttcc gtgtctgcat
ctgtaggaga cagagtcacc 60atcacttgtc gggcgagtca gggtattagc ggctggttag
cctggtatca gcagaaacca 120gagaaagccc ctaagctcct gatctatgcg
gcatccagtt tgcaacgtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagat ttcactctca ccatcagcag cctgcagcct 240gaagattttg
caacttacta ttgtcaacag gctaacagtt tcccccccac cttcggccaa
300gggacacgac tggagattaa a 321107324DNAArtificial sequenceLight
chain variable region of SC04-040 107cagcctgtgc tgactcagcc
cccctcggtg tcagtggccc caggacagac ggccaggatt 60tcctgtgggg gagacaacat
tggaactaat actgtgcagt ggtaccagca gaagccaggc 120caggcccctg
tcctggtcgt ctatgatgat agcgaccggc cctcagggat ccctgagcga
180ttctctggct ccaactctgg ggacacggcc accctgacca tcagcagggt
cgaggccggg 240gatgaggccg attattactg tcaggtgtgg gatgacagta
gtgatctggt ggtattcggc 300ggagggacca aggtcaccgt ccta
324108321DNAArtificial sequenceLight chain variable region of
SC04-060 108gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
cagagtcacc 60atcacttgcc gggcaagtca gggcattagc acctatttaa attggtatca
gcagaaacca 120gggaaagccc ctaacctcct gatctacggt gcatctaatt
tgcaaagtgg ggtcccatca 180aggttcagtg gcagtgaatc tgggacagat
ttcactctca ccatcagcag tctacaacct 240gaagattttg caacttacta
ctgtcagcag agtttcacta cccctcgcac gttcggccaa 300gggaccaagc
tggagatcaa a 321109321DNAArtificial sequenceLight chain variable
region of SC04-073 109gacatccagt tgacccagtc gccatccttc ctgtctgcat
ctgtaggaga cagagtcacc 60atcacttgcc gggccagtca cagtattagt agctggttgg
cctggtatca gcagaaacca 120gggaaagccc ctaagctcct gatctataag
gcatctagtt tagaaagtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagat ttcactctca ccatcagcag cctgcagcct 240gaagattttg
caacttatta ctgtctacaa gattacaatt accctcggac gttcggccaa
300gggaccaagc tggagatcaa a 321110321DNAArtificial sequenceLight
chain variable region of SC04-097 110gacatccaga tgacccagtc
tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60atcacttgcc gggcaagtca
gggcattaga aatgatttag gctggtatca gcagaaacca 120gggaaagccc
ctaagctcct gatctatgct gcatccagtt tacaaagtgg ggtcccatca
180aggttcagcg gcagtggatc tggcacagat ttcactctca ccatcagcag
cctgcagcct 240gaagattttg caacttatta ctgtctacaa gattacaatt
accctcggac gttcggccaa 300gggaccaagg tggagatcaa a
321111321DNAArtificial sequenceLight chain variable region of
SC04-098 111gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
cagagtcacc 60atcacttgcc gggcaagtca gggcattaga aatgatttag gctggtatca
gcagaaacca 120gggaaagccc ctaagctcct gatctatgct gcatccagtt
tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc tgggacagat
ttcactctca ccatcagcag cctgcagcct 240gaagattttg caacttatta
ctgtcaacag cttaatagtt accctcccac tttcggcgga 300gggaccaagg
tggaaatcaa a 321112321DNAArtificial sequenceLight chain variable
region of SC04-103 112gacatccagt tgacccagtc tccatcttcc gtgtctgcat
ctgtaggaga cagagtcacc 60atcacttgtc gggcgagtca gggtattagc agctggttag
cctggtatca gcagaagcca 120gggaaagccc ctaggtccct gatctatgat
gcatccagtt tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagac tttactctca ccatcagcag cctgcagcct 240gaagattttg
caacttacta ttgtcaacag gctgacagtt tcccgatcac cttcggccaa
300gggacacgac tggagattaa a 321113327DNAArtificial sequenceLight
chain variable region of SC04-104 113gacatccagt tgacccagtc
tccttccacc ctgtctgcat ctgtaggaga cagagtcacc 60atcacttgcc gggccagtca
gattcttggt cactggttgc ccttgtcctg gtatcagcag 120aaaccaggta
aagcccctaa actcctgatc tctaaggcgt ctagtttaga aagtggagtc
180ccaccaaggt tcagcggcag tggatctggg tcagatttca ctctcaccat
cagcagcctg 240cagcccgatg attttgcaac ttattactgc ctccaatatc
atgagtaccc gctcaccttc 300ggcggaggga ccaagctgga gatcaaa
327114321DNAArtificial sequenceLight chain variable region of
SC04-108 114gacatccagt tgacccagtc tccatcctca ctgtctgcat ctgtaggaga
cagagtcacc 60atcacttgtc gggcgagtca gggcattagc agtcatttag tctggtatca
gcagaaacca 120gggaaagccc ctaagtccct gatctatgct gcatccagtt
tgcaaagtgg ggtcccatca 180aggttcagcg gcagtgaatc tgcgacagat
ttcactctca ccatcagcag cctgcagcct 240gaagattttg caacttatta
ctgccaacag tattacagtt accctatcac cttcggccaa 300gggacacgac
tggagattaa a 321115321DNAArtificial sequenceLight chain variable
region of SC04-120 115gacatccagt tgacccagtc tccttccacc ctgtctgcat
ctgtaggaga cagagtcacc 60atcacttgcc gggccagtca gggcattaac agttatttag
cctggtatca gcaagaacca 120gggaaagccc ctaaactcct gatctatgct
gcatccactt tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagaa ttcactctca caatcagcag cctgcagcct 240gaagattttg
caacttatta ctgtcaacag cttaatagtt accccttcac tttcggccct
300gggaccaaag tggatatcaa a 321116321DNAArtificial sequenceLight
chain variable region of SC04-125 116gacatccaga tgacccagtc
tccatcttcc gtgtctgcat ctgtaggaga cagagtcacc 60atcacttgtc gggcgagtca
gggcattagc agttatttag cctggtatca gcaaaaacca 120gggaaagccc
ctaagctcct gatctatgat gcctccagtt tggaaagtgg ggtcccatca
180aggttcagcg gcagtggatc tgggacagaa ttcactctca ccatcagcag
cctgcagcct 240gatgattttg caacttatta ctgtcaacaa cttaacagtt
acccactcac tttcggcgga 300gggaccaagg tggagatcaa a
321117327DNAArtificial sequenceLight chain variable region of
SC04-126 117cagtctgtgc tgactcagcc accctcagtg tcagtggccc caggaaagac
ggccaggatt 60acctgtgggg gaaacaacat tggaagtaaa agtgtgcact ggtaccagca
gaagccaggc 120caggcccctg tgctggtcat ctattatgat agcgaccggc
cctcagggat ccctgagcga 180ttctctggct ccaactctgg gaacacggcc
accctgacca tcagcagggt cgaagccggg 240gatgaggctg actattactg
tcaggtgtgg gatagtagta gtgatcatcc ctatgtcttc 300ggaactggga
ccaagctgac cgtccta 327118321DNAArtificial sequenceLight chain
variable region of SC04-140 118gacatccaga tgacccagtc tccatcctcc
ctgtctgcat ctgtcggaga cagagtcacc 60atcacttgcc gggcaagtca gggcattagc
agtgctttag cctggtatca gcagaaacca 120gggaaagctc ctaagctcct
gatctatgat gcctccagtt tggaaagtgg ggtcccatca 180aggttcagcg
gcagtggatc tgggacagat ttcactctca ccatcagcag cctgcagcct
240gaagattttg caacttatta ctgtcaacag tttaatagtt acccgctcac
tttcggcgga 300gggaccaagg tggaaatcaa a 321119321DNAArtificial
sequenceLight chain variable region of SC04-144 119gacatccagt
tgacgcagtc tccatcctcc ctgtctgcat ctgtaggaga cagagtcacc 60atcacttgcc
gggccagtca gggcattagc agttatttag cctggtatca gcaaaaacca
120gggaaaggcc ctaagctcct gatctatgct gcatccactt tacaaagtgg
ggtcccatca 180aggttcagcg gcagtggatc tgggacagac ttcagtctca
ccatcagtag cctgcagcct 240gaagatttag caacttatta ctgccaacag
tatgatagtt accctctcac tttcggcgga 300gggaccaagg tggaaatcaa a
321120321DNAArtificial sequenceLight chain variable region of
SC04-146 120gatgttgtga tgactcagtc tccagccacc ctgtctgtgt ctccagggga
aagcgccaca 60ctcttctgca gggccagtga gagtgtttat agcaacttgg cctggtatca
gcacaaacct 120ggccgggctc ccaggctcct catctatggt gcatccacca
gggccactgg tatcccagcc 180aggttcgatg gcactgggtc tgggacagac
ttcacactca ccatcagcag cctgcagtct 240gaagattttg cagtttatta
ctgtcagcaa tataatgact ggccgatcac cttcggccaa 300gggacacgac
tggagattaa a 321121321DNAArtificial sequenceLight chain variable
region of SC04-164 121gacatccagt tgacccagtc tccatcttct gtgtctgcat
ctgtaggaga cagagtcacc 60atcacttgtc gggcgagtca gggtattagc agctggttag
cctggtatca gcagaaacca 120gggaaagccc ctaagctcct gatctatgct
gcatccagtt tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc
tgggacagat ttcactctca ctatcagcag cctgcagcct 240gaagattttg
caacttacta ttgtcaacag gctaacagtt tcccgctcac tttcggcgga
300gggaccaaag tggatatcaa a 3211222107DNAArtificial sequenceHeavy
chain CR57 122caggtgcagc tggtgcagag cggagccgag gtgaagaagc
ccggcagcag cgtgaaggtg 60agctgcaagg ccagcggcgg caccttcaac aggtacaccg
tgaactgggt gagacaggcc 120ccaggccagg gcctggagtg gatgggcggc
atcatcccta tcttcggcac cgccaactac 180gcccagagat tccagggcag
gctcaccatc accgccgacg agagcaccag caccgcctac 240atggagctga
gcagcctgag aagcgatgac accgccgtgt acttctgcgc cagggagaac
300ctggataaca gcggcaccta ctactacttc agcggctggt tcgacccctg
gggccagggc 360accctggtga ccgtgagctc aggtgagtgc ggccgcgagc
ccagacactg gacgctgaac 420ctcgcggaca gttaagaacc caggggcctc
tgcgccctgg gcccagctct gtcccacacc 480gcggtcacat ggcaccacct
ctcttgcagc ctccaccaag ggcccatcgg tcttccccct 540ggcaccctcc
tccaagagca cctctggggg cacagcggcc ctgggctgcc tggtcaagga
600ctacttcccc gaaccggtga cggtgtcgtg gaactcaggc gccctgacca
gcggcgtgca 660caccttcccg gctgtcctac agtcctcagg actctactcc
ctcagcagcg tggtgaccgt 720gccctccagc agcttgggca cccagaccta
catctgcaac gtgaatcaca agcccagcaa 780caccaaggtg gacaagagag
ttggtgagag gccagcacag ggagggaggg tgtctgctgg 840aagccaggct
cagcgctcct gcctggacgc atcccggcta tgcagtccca gtccagggca
900gcaaggcagg ccccgtctgc ctcttcaccc ggaggcctct gcccgcccca
ctcatgctca 960gggagagggt cttctggctt tttccccagg ctctgggcag
gcacaggcta ggtgccccta 1020acccaggccc tgcacacaaa ggggcaggtg
ctgggctcag acctgccaag agccatatcc 1080gggaggaccc tgcccctgac
ctaagcccac cccaaaggcc aaactctcca ctccctcagc 1140tcggacacct
tctctcctcc cagattccag taactcccaa tcttctctct gcagagccca
1200aatcttgtga caaaactcac acatgcccac cgtgcccagg taagccagcc
caggcctcgc 1260cctccagctc aaggcgggac aggtgcccta gagtagcctg
catccaggga caggccccag 1320ccgggtgctg acacgtccac ctccatctct
tcctcagcac ctgaactcct
ggggggaccg 1380tcagtcttcc tcttcccccc aaaacccaag gacaccctca
tgatctcccg gacccctgag 1440gtcacatgcg tggtggtgga cgtgagccac
gaagaccctg aggtcaagtt caactggtac 1500gtggacggcg tggaggtgca
taatgccaag acaaagccgc gggaggagca gtacaacagc 1560acgtaccgtg
tggtcagcgt cctcaccgtc ctgcaccagg actggctgaa tggcaaggag
1620tacaagtgca aggtctccaa caaagccctc ccagccccca tcgagaaaac
catctccaaa 1680gccaaaggtg ggacccgtgg ggtgcgaggg ccacatggac
agaggccggc tcggcccacc 1740ctctgccctg agagtgaccg ctgtaccaac
ctctgtccct acagggcagc cccgagaacc 1800acaggtgtac accctgcccc
catcccggga ggagatgacc aagaaccagg tcagcctgac 1860ctgcctggtc
aaaggcttct atcccagcga catcgccgtg gagtgggaga gcaatgggca
1920gccggagaac aactacaaga ccacgcctcc cgtgctggac tccgacggct
ccttcttcct 1980ctatagcaag ctcaccgtgg acaagagcag gtggcagcag
gggaacgtct tctcatgctc 2040cgtgatgcat gaggctctgc acaaccacta
cacgcagaag agcctctccc tgtctccggg 2100taaatga
2107123457PRTArtificial sequenceHeavy chain CR57 123Gln Val Gln Leu
Val Gln Ser Gly Ala Glu Val Lys Lys Pro Gly Ser1 5 10 15Ser Val Lys
Val Ser Cys Lys Ala Ser Gly Gly Thr Phe Asn Arg Tyr 20 25 30Thr Val
Asn Trp Val Arg Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45Gly
Gly Ile Ile Pro Ile Phe Gly Thr Ala Asn Tyr Ala Gln Arg Phe 50 55
60Gln Gly Arg Leu Thr Ile Thr Ala Asp Glu Ser Thr Ser Thr Ala Tyr65
70 75 80Met Glu Leu Ser Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Phe
Cys 85 90 95Ala Arg Glu Asn Leu Asp Asn Ser Gly Thr Tyr Tyr Tyr Phe
Ser Gly 100 105 110Trp Phe Asp Pro Trp Gly Gln Gly Thr Leu Val Thr
Val Ser Ser Ala 115 120 125Ser Thr Lys Gly Pro Ser Val Phe Pro Leu
Ala Pro Ser Ser Lys Ser 130 135 140Thr Ser Gly Gly Thr Ala Ala Leu
Gly Cys Leu Val Lys Asp Tyr Phe145 150 155 160Pro Glu Pro Val Thr
Val Ser Trp Asn Ser Gly Ala Leu Thr Ser Gly 165 170 175Val His Thr
Phe Pro Ala Val Leu Gln Ser Ser Gly Leu Tyr Ser Leu 180 185 190Ser
Ser Val Val Thr Val Pro Ser Ser Ser Leu Gly Thr Gln Thr Tyr 195 200
205Ile Cys Asn Val Asn His Lys Pro Ser Asn Thr Lys Val Asp Lys Arg
210 215 220Val Glu Pro Lys Ser Cys Asp Lys Thr His Thr Cys Pro Pro
Cys Pro225 230 235 240Ala Pro Glu Leu Leu Gly Gly Pro Ser Val Phe
Leu Phe Pro Pro Lys 245 250 255Pro Lys Asp Thr Leu Met Ile Ser Arg
Thr Pro Glu Val Thr Cys Val 260 265 270Val Val Asp Val Ser His Glu
Asp Pro Glu Val Lys Phe Asn Trp Tyr 275 280 285Val Asp Gly Val Glu
Val His Asn Ala Lys Thr Lys Pro Arg Glu Glu 290 295 300Gln Tyr Asn
Ser Thr Tyr Arg Val Val Ser Val Leu Thr Val Leu His305 310 315
320Gln Asp Trp Leu Asn Gly Lys Glu Tyr Lys Cys Lys Val Ser Asn Lys
325 330 335Ala Leu Pro Ala Pro Ile Glu Lys Thr Ile Ser Lys Ala Lys
Gly Gln 340 345 350Pro Arg Glu Pro Gln Val Tyr Thr Leu Pro Pro Ser
Arg Glu Glu Met 355 360 365Thr Lys Asn Gln Val Ser Leu Thr Cys Leu
Val Lys Gly Phe Tyr Pro 370 375 380Ser Asp Ile Ala Val Glu Trp Glu
Ser Asn Gly Gln Pro Glu Asn Asn385 390 395 400Tyr Lys Thr Thr Pro
Pro Val Leu Asp Ser Asp Gly Ser Phe Phe Leu 405 410 415Tyr Ser Lys
Leu Thr Val Asp Lys Ser Arg Trp Gln Gln Gly Asn Val 420 425 430Phe
Ser Cys Ser Val Met His Glu Ala Leu His Asn His Tyr Thr Gln 435 440
445Lys Ser Leu Ser Leu Ser Pro Gly Lys 450 455124859DNAArtificial
sequenceLight chain of CR57 124cagagcgccc tcacccagcc cagaagcgtg
agcggcagcc ctggccagag cgtgaccatc 60agctgcaccg gcaccagcag cgacatcggc
ggctacaact tcgtgagctg gtatcagcag 120caccccggca aggcccctaa
gctcatgatc tacgacgcca ccaagagacc cagcggcgtg 180cccgacagat
tcagcggcag caagagcggc aacaccgcca gcctcaccat cagcggactg
240caggccgagg acgaggccga ctactactgc tgcagctacg ccggcgacta
cacccctggc 300gtggtgttcg gcggaggcac caagcttacc gtcctaggta
agtgcacttt gcggccgcta 360ggaagaaact caaaacatca agattttaaa
tacgcttctt ggtctccttg ctataattat 420ctgggataag catgctgttt
tctgtctgtc cctaacatgc cctgtgatta tccgcaaaca 480acacacccaa
gggcagaact ttgttactta aacaccatcc tgtttgcttc tttcctcagg
540acagcccaag gctgcaccat ctgtgaccct gttccccccc tcctccgagg
agctgcaggc 600caacaaggcc accctggtgt gcctcatcag cgacttctac
cctggcgccg tgaccgtggc 660ctggaaggcc gacagcagcc ccgtgaaggc
cggcgtggag accaccaccc ccagcaagca 720gagcaacaac aagtacgccg
ccagcagcta cctgagcctc acccccgagc agtggaagag 780ccaccggagc
tacagctgcc aggtgaccca cgagggcagc accgtggaga agaccgtggc
840ccccaccgag tgcagctag 859125218PRTArtificial sequenceLight chain
of CR57 125Gln Ser Ala Leu Thr Gln Pro Arg Ser Val Ser Gly Ser Pro
Gly Gln1 5 10 15Ser Val Thr Ile Ser Cys Thr Gly Thr Ser Ser Asp Ile
Gly Gly Tyr 20 25 30Asn Phe Val Ser Trp Tyr Gln Gln His Pro Gly Lys
Ala Pro Lys Leu 35 40 45Met Ile Tyr Asp Ala Thr Lys Arg Pro Ser Gly
Val Pro Asp Arg Phe 50 55 60Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser
Leu Thr Ile Ser Gly Leu65 70 75 80Gln Ala Glu Asp Glu Ala Asp Tyr
Tyr Cys Cys Ser Tyr Ala Gly Asp 85 90 95Tyr Thr Pro Gly Val Val Phe
Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105 110Gly Gln Pro Lys Ala
Ala Pro Ser Val Thr Leu Phe Pro Pro Ser Ser 115 120 125Glu Glu Leu
Gln Ala Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp 130 135 140Phe
Tyr Pro Gly Ala Val Thr Val Ala Trp Lys Ala Asp Ser Ser Pro145 150
155 160Val Lys Ala Gly Val Glu Thr Thr Thr Pro Ser Lys Gln Ser Asn
Asn 165 170 175Lys Tyr Ala Ala Ser Ser Tyr Leu Ser Leu Thr Pro Glu
Gln Trp Lys 180 185 190Ser His Arg Ser Tyr Ser Cys Gln Val Thr His
Glu Gly Ser Thr Val 195 200 205Glu Lys Thr Val Ala Pro Thr Glu Cys
Ser 210 2151262089DNAArtificial sequenceHeavy chain of CRJB
126cagatcaccc tgaaggagac cggccccacc ctggtgaagc ccacccagac
cctcaccctc 60acctgcacct tcagcggctt cagcctgagc accagcggcg tgggcgtggg
ctggatcaga 120cagccccctg gcaaggccct ggagtgggtg accctcatct
actgggacga cgacaagaga 180tacagcccca gcctggagaa cagggtgacc
atccggaagg acaccagcaa gaaccaggtg 240gccctcacca tgaccaacat
ggaccccctg gataccggca cctactactg cgcccacagg 300cagcacatca
gcagcttccc ctggttcgac agctggggcc agggcacact ggtgaccgtg
360agctcaggtg agtgcggccg cgagcccaga cactggacgc tgaacctcgc
ggacagttaa 420gaacccaggg gcctctgcgc cctgggccca gctctgtccc
acaccgcggt cacatggcac 480cacctctctt gcagcctcca ccaagggccc
atcggtcttc cccctggcac cctcctccaa 540gagcacctct gggggcacag
cggccctggg ctgcctggtc aaggactact tccccgaacc 600ggtgacggtg
tcgtggaact caggcgccct gaccagcggc gtgcacacct tcccggctgt
660cctacagtcc tcaggactct actccctcag cagcgtggtg accgtgccct
ccagcagctt 720gggcacccag acctacatct gcaacgtgaa tcacaagccc
agcaacacca aggtggacaa 780gagagttggt gagaggccag cacagggagg
gagggtgtct gctggaagcc aggctcagcg 840ctcctgcctg gacgcatccc
ggctatgcag tcccagtcca gggcagcaag gcaggccccg 900tctgcctctt
cacccggagg cctctgcccg ccccactcat gctcagggag agggtcttct
960ggctttttcc ccaggctctg ggcaggcaca ggctaggtgc ccctaaccca
ggccctgcac 1020acaaaggggc aggtgctggg ctcagacctg ccaagagcca
tatccgggag gaccctgccc 1080ctgacctaag cccaccccaa aggccaaact
ctccactccc tcagctcgga caccttctct 1140cctcccagat tccagtaact
cccaatcttc tctctgcaga gcccaaatct tgtgacaaaa 1200ctcacacatg
cccaccgtgc ccaggtaagc cagcccaggc ctcgccctcc agctcaaggc
1260gggacaggtg ccctagagta gcctgcatcc agggacaggc cccagccggg
tgctgacacg 1320tccacctcca tctcttcctc agcacctgaa ctcctggggg
gaccgtcagt cttcctcttc 1380cccccaaaac ccaaggacac cctcatgatc
tcccggaccc ctgaggtcac atgcgtggtg 1440gtggacgtga gccacgaaga
ccctgaggtc aagttcaact ggtacgtgga cggcgtggag 1500gtgcataatg
ccaagacaaa gccgcgggag gagcagtaca acagcacgta ccgtgtggtc
1560agcgtcctca ccgtcctgca ccaggactgg ctgaatggca aggagtacaa
gtgcaaggtc 1620tccaacaaag ccctcccagc ccccatcgag aaaaccatct
ccaaagccaa aggtgggacc 1680cgtggggtgc gagggccaca tggacagagg
ccggctcggc ccaccctctg ccctgagagt 1740gaccgctgta ccaacctctg
tccctacagg gcagccccga gaaccacagg tgtacaccct 1800gcccccatcc
cgggaggaga tgaccaagaa ccaggtcagc ctgacctgcc tggtcaaagg
1860cttctatccc agcgacatcg ccgtggagtg ggagagcaat gggcagccgg
agaacaacta 1920caagaccacg cctcccgtgc tggactccga cggctccttc
ttcctctata gcaagctcac 1980cgtggacaag agcaggtggc agcaggggaa
cgtcttctca tgctccgtga tgcatgaggc 2040tctgcacaac cactacacgc
agaagagcct ctccctgtct ccgggtaaa 2089127452PRTArtificial
sequenceHeavy chain of CRJB 127Gln Ile Thr Leu Lys Glu Thr Gly Pro
Thr Leu Val Lys Pro Thr Gln1 5 10 15Thr Leu Thr Leu Thr Cys Thr Phe
Ser Gly Phe Ser Leu Ser Thr Ser 20 25 30Gly Val Gly Val Gly Trp Ile
Arg Gln Pro Pro Gly Lys Ala Leu Glu 35 40 45Trp Val Thr Leu Ile Tyr
Trp Asp Asp Asp Lys Arg Tyr Ser Pro Ser 50 55 60Leu Glu Asn Arg Val
Thr Ile Arg Lys Asp Thr Ser Lys Asn Gln Val65 70 75 80Ala Leu Thr
Met Thr Asn Met Asp Pro Leu Asp Thr Gly Thr Tyr Tyr 85 90 95Cys Ala
His Arg Gln His Ile Ser Ser Phe Pro Trp Phe Asp Ser Trp 100 105
110Gly Gln Gly Thr Leu Val Thr Val Ser Ser Ala Ser Thr Lys Gly Pro
115 120 125Ser Val Phe Pro Leu Ala Pro Ser Ser Lys Ser Thr Ser Gly
Gly Thr 130 135 140Ala Ala Leu Gly Cys Leu Val Lys Asp Tyr Phe Pro
Glu Pro Val Thr145 150 155 160Val Ser Trp Asn Ser Gly Ala Leu Thr
Ser Gly Val His Thr Phe Pro 165 170 175Ala Val Leu Gln Ser Ser Gly
Leu Tyr Ser Leu Ser Ser Val Val Thr 180 185 190Val Pro Ser Ser Ser
Leu Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn 195 200 205His Lys Pro
Ser Asn Thr Lys Val Asp Lys Arg Val Glu Pro Lys Ser 210 215 220Cys
Asp Lys Thr His Thr Cys Pro Pro Cys Pro Ala Pro Glu Leu Leu225 230
235 240Gly Gly Pro Ser Val Phe Leu Phe Pro Pro Lys Pro Lys Asp Thr
Leu 245 250 255Met Ile Ser Arg Thr Pro Glu Val Thr Cys Val Val Val
Asp Val Ser 260 265 270His Glu Asp Pro Glu Val Lys Phe Asn Trp Tyr
Val Asp Gly Val Glu 275 280 285Val His Asn Ala Lys Thr Lys Pro Arg
Glu Glu Gln Tyr Asn Ser Thr 290 295 300Tyr Arg Val Val Ser Val Leu
Thr Val Leu His Gln Asp Trp Leu Asn305 310 315 320Gly Lys Glu Tyr
Lys Cys Lys Val Ser Asn Lys Ala Leu Pro Ala Pro 325 330 335Ile Glu
Lys Thr Ile Ser Lys Ala Lys Gly Gln Pro Arg Glu Pro Gln 340 345
350Val Tyr Thr Leu Pro Pro Ser Arg Glu Glu Met Thr Lys Asn Gln Val
355 360 365Ser Leu Thr Cys Leu Val Lys Gly Phe Tyr Pro Ser Asp Ile
Ala Val 370 375 380Glu Trp Glu Ser Asn Gly Gln Pro Glu Asn Asn Tyr
Lys Thr Thr Pro385 390 395 400Pro Val Leu Asp Ser Asp Gly Ser Phe
Phe Leu Tyr Ser Lys Leu Thr 405 410 415Val Asp Lys Ser Arg Trp Gln
Gln Gly Asn Val Phe Ser Cys Ser Val 420 425 430Met His Glu Ala Leu
His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu 435 440 445Ser Pro Gly
Lys 450128841DNAArtificial sequenceLight chain of CRJB
128agctacgtgc tcacccagcc ccccagcgtg agcgtggccc ctggcaagac
cgccagaatc 60aactgcggcg gcaacaacat cgagtaccgg agcgtgcact ggtatcagca
gaagagcggc 120caggcccccg tggccgtgat ctacgacaac agcgacagac
ctagcggcat ccccgagaga 180ttcagcggca gcaagagcgg caacaccgcc
accctcacca tcagcagagt ggaggccggc 240gacgaggccg actactactg
ccaggtgtgg gacatcagca gcgatgtggt gttcggcgga 300ggcaccaagc
ttaccgtcct aggtaagtgc actttgcggc cgctaggaag aaactcaaaa
360catcaagatt ttaaatacgc ttcttggtct ccttgctata attatctggg
ataagcatgc 420tgttttctgt ctgtccctaa catgccctgt gattatccgc
aaacaacaca cccaagggca 480gaactttgtt acttaaacac catcctgttt
gcttctttcc tcaggacagc ccaaggctgc 540accatctgtg accctgttcc
ccccctcctc cgaggagctg caggccaaca aggccaccct 600ggtgtgcctc
atcagcgact tctaccctgg cgccgtgacc gtggcctgga aggccgacag
660cagccccgtg aaggccggcg tggagaccac cacccccagc aagcagagca
acaacaagta 720cgccgccagc agctacctga gcctcacccc cgagcagtgg
aagagccacc ggagctacag 780ctgccaggtg acccacgagg gcagcaccgt
ggagaagacc gtggccccca ccgagtgcag 840c 841129213PRTArtificial
sequenceLight chain of CRJB 129Ser Tyr Val Leu Thr Gln Pro Pro Ser
Val Ser Val Ala Pro Gly Lys1 5 10 15Thr Ala Arg Ile Asn Cys Gly Gly
Asn Asn Ile Glu Tyr Arg Ser Val 20 25 30His Trp Tyr Gln Gln Lys Ser
Gly Gln Ala Pro Val Ala Val Ile Tyr 35 40 45Asp Asn Ser Asp Arg Pro
Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser 50 55 60Lys Ser Gly Asn Thr
Ala Thr Leu Thr Ile Ser Arg Val Glu Ala Gly65 70 75 80Asp Glu Ala
Asp Tyr Tyr Cys Gln Val Trp Asp Ile Ser Ser Asp Val 85 90 95Val Phe
Gly Gly Gly Thr Lys Leu Thr Val Leu Gly Gln Pro Lys Ala 100 105
110Ala Pro Ser Val Thr Leu Phe Pro Pro Ser Ser Glu Glu Leu Gln Ala
115 120 125Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp Phe Tyr Pro
Gly Ala 130 135 140Val Thr Val Ala Trp Lys Ala Asp Ser Ser Pro Val
Lys Ala Gly Val145 150 155 160Glu Thr Thr Thr Pro Ser Lys Gln Ser
Asn Asn Lys Tyr Ala Ala Ser 165 170 175Ser Tyr Leu Ser Leu Thr Pro
Glu Gln Trp Lys Ser His Arg Ser Tyr 180 185 190Ser Cys Gln Val Thr
His Glu Gly Ser Thr Val Glu Lys Thr Val Ala 195 200 205Pro Thr Glu
Cys Ser 21013012DNARabies virusmisc_featurePart of glycoprotein of
CVS-11, E57A2, E57B1, E57B2, E57B3 and E57C3 130atacaccatc tc
1213112DNARabies virusmisc_featurePart of glycoprotein of E57A3
131atacaacatc tc 1213218DNARabies virusmisc_featurePart of
glycoprotein of CVS-11 132ctcaagttat gtggagtt 1813318DNARabies
virusmisc_featurePart of glycoprotein of E57A2 133ctcaagttat
gtgaagtt 1813418DNARabies virusmisc_featurePart of glycoprotein of
E57A3, E57B1 and E57B3 134ctcgagttat gtggagtt 1813518DNARabies
virusmisc_featurePart of glycoprotein of E57B2 and E57C3
135ctcaatttat gtggagtt 1813616PRTRabies virusMISC_FEATUREPart of
glycoprotein of CVS-11, E57A2, E57B1, E57B2, E57B3 and E57C3 136Gly
Pro Trp Ser Pro Ile Asp Ile His His Leu Ser Cys Pro Asn Asn1 5 10
1513716PRTRabies virusMISC_FEATUREPart of glycoprotein of E57A3
137Gly Pro Trp Ser Pro Ile Asp Ile Gln His Leu Ser Cys Pro Asn Asn1
5 10 1513823PRTRabies virusMISC_FEATUREPart of glycoprotein of
CVS-11 138Ser Leu Lys Gly Ala Cys Arg Leu Lys Leu Cys Gly Val Leu
Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp 2013923PRTRabies
virusMISC_FEATUREPart of glycoprotein of E57A2 139Ser Leu Lys Gly
Ala Cys Arg Leu Lys Leu Cys Glu Val Leu Gly Leu1 5 10 15Arg Leu Met
Asp Gly Thr Trp 2014023PRTRabies virusMISC_FEATUREPart of
glycoprotein of E57A3, E57B1 and E57B3 140Ser Leu Lys Gly Ala Cys
Arg Leu Glu Leu Cys Gly Val Leu Gly Leu1 5 10 15Arg Leu Met Asp Gly
Thr Trp 2014123PRTRabies virusMISC_FEATUREPart of glycoprotein of
E57B2 and E57C3 141Ser Leu Lys Gly Ala Cys Arg Leu Asn Leu Cys Gly
Val Leu Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp
2014215DNARabies
virusmisc_featurePart of glycoprotein of CVS-11 142cccgagaatc cgaga
1514315DNARabies virusmisc_featurePart of glycoprotein of EJB2B,
EJB2C, EJB2D, EJB2E, EJB2F and EJB3F 143cccgaggatc cgaga
1514415DNARabies virusmisc_featurePart of glycoprotein of CVS-11
144tgtggagttc ttgga 1514515DNARabies virusmisc_featurePart of
glycoprotein of EJB2B, EJB2C and EJB2F 145tgtgaagttc ctgga
1514615DNARabies virusmisc_featurePart of glycoprotein of EJB2D,
EJB2E and EJB3F 146tgtggagttc ctgga 1514713PRTRabies
virusMISC_FEATUREPart of glycoprotein of CVS-11 147Tyr Thr Ile Trp
Met Pro Glu Asn Pro Arg Leu Gly Met1 5 1014813PRTRabies
virusMISC_FEATUREPart of glycoprotein of EJB2B, EJB2C, EJB2D,
EJB2E, EJB2F and EJB3F 148Tyr Thr Ile Trp Met Pro Glu Asp Pro Arg
Leu Gly Met1 5 1014923PRTRabies virusMISC_FEATUREPart of
glycoprotein of CVS-11 149Ser Leu Lys Gly Ala Cys Arg Leu Lys Leu
Cys Gly Val Leu Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp
2015023PRTRabies virusMISC_FEATUREPart of glycoprotein of EJB2B,
EJB2C and EJB2F 150Ser Leu Lys Gly Ala Cys Arg Leu Lys Leu Cys Glu
Val Pro Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp
2015123PRTRabies virusMISC_FEATUREPart of glycoprotein of EJB2D,
EJB2E and EJB3F 151Ser Leu Lys Gly Ala Cys Arg Leu Lys Leu Cys Gly
Val Pro Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp
2015224DNAArtificial sequenceAnti-sense primer HuCkappa
152acactctccc ctgttgaagc tctt 2415323DNAArtificial
sequenceAnti-sense primer HuClambda2 153tgaacattct gtaggggcca ctg
2315423DNAArtificial sequenceAnti-sense primer HuClambda7
154agagcattct gcaggggcca ctg 231554941DNAArtificial sequenceVector
PDV-C06 155aagcttgcat gcaaattcta tttcaaggag acagtcataa tgaaatacct
attgcctacg 60gcagccgctg gattgttatt actcgcggcc cagccggcca tggccgaggt
gtttgactaa 120tggggcgcgc ctcagggaac cctggtcacc gtctcgagcg
gtacgggcgg ttcaggcgga 180accggcagcg gcactggcgg gtcgacggaa
attgtgctca cacagtctcc agccaccctg 240tctttgtctc caggggaaag
agccaccctc tcctgcaggg ccagtcagag tgttagcagc 300tacttagcct
ggtaccaaca gaaacctggc caggctccca ggctcctcat ctatgatgca
360tccaacaggg ccactggcat cccagccagg ttcagtggca gtgggtctgg
gacagacttc 420actctcacca tcagcagcct agagcctgaa gattttgcag
tttattactg tcagcagcgt 480agcaactggc ctccggcttt cggcggaggg
accaaggtgg agatcaaacg tgcggccgca 540catcatcatc accatcacgg
ggccgcatat accgatattg aaatgaaccg cctgggcaaa 600ggggccgcat
agactgttga aagttgttta gcaaaacctc atacagaaaa ttcatttact
660aacgtctgga aagacgacaa aactttagat cgttacgcta actatgaggg
ctgtctgtgg 720aatgctacag gcgttgtggt ttgtactggt gacgaaactc
agtgttacgg tacatgggtt 780cctattgggc ttgctatccc tgaaaatgag
ggtggtggct ctgagggtgg cggttctgag 840ggtggcggtt ctgagggtgg
cggtactaaa cctcctgagt acggtgatac acctattccg 900ggctatactt
atatcaaccc tctcgacggc acttatccgc ctggtactga gcaaaacccc
960gctaatccta atccttctct tgaggagtct cagcctctta atactttcat
gtttcagaat 1020aataggttcc gaaataggca gggtgcatta actgtttata
cgggcactgt tactcaaggc 1080actgaccccg ttaaaactta ttaccagtac
actcctgtat catcaaaagc catgtatgac 1140gcttactgga acggtaaatt
cagagactgc gctttccatt ctggctttaa tgaggatcca 1200ttcgtttgtg
aatatcaagg ccaatcgtct gacctgcctc aacctcctgt caatgctggc
1260ggcggctctg gtggtggttc tggtggcggc tctgagggtg gcggctctga
gggtggcggt 1320tctgagggtg gcggctctga gggtggcggt tccggtggcg
gctccggttc cggtgatttt 1380gattatgaaa aaatggcaaa cgctaataag
ggggctatga ccgaaaatgc cgatgaaaac 1440gcgctacagt ctgacgctaa
aggcaaactt gattctgtcg ctactgatta cggtgctgct 1500atcgatggtt
tcattggtga cgtttccggc cttgctaatg gtaatggtgc tactggtgat
1560tttgctggct ctaattccca aatggctcaa gtcggtgacg gtgataattc
acctttaatg 1620aataatttcc gtcaatattt accttctttg cctcagtcgg
ttgaatgtcg cccttatgtc 1680tttggcgctg gtaaaccata tgaattttct
attgattgtg acaaaataaa cttattccgt 1740ggtgtctttg cgtttctttt
atatgttgcc acctttatgt atgtattttc gacgtttgct 1800aacatactgc
gtaataagga gtcttaataa gaattcactg gccgtcgttt tacaacgtcg
1860tgactgggaa aaccctggcg ttacccaact taatcgcctt gcagcacatc
cccctttcgc 1920cagctggcgt aatagcgaag aggcccgcac cgatcgccct
tcccaacagt tgcgcagcct 1980gaatggcgaa tggcgcctga tgcggtattt
tctccttacg catctgtgcg gtatttcaca 2040ccgcatacgt caaagcaacc
atagtacgcg ccctgtagcg gcgcattaag cgcggcgggt 2100gtggtggtta
cgcgcagcgt gaccgctaca cttgccagcg ccctagcgcc cgctcctttc
2160gctttcttcc cttcctttct cgccacgttc gccggctttc cccgtcaagc
tctaaatcgg 2220gggctccctt tagggttccg atttagtgct ttacggcacc
tcgaccccaa aaaacttgat 2280ttgggtgatg gttcacgtag tgggccatcg
ccctgataga cggtttttcg ccctttgacg 2340ttggagtcca cgttctttaa
tagtggactc ttgttccaaa ctggaacaac actcaaccct 2400atctcgggct
attcttttga tttataaggg attttgccga tttcggccta ttggttaaaa
2460aatgagctga tttaacaaaa atttaacgcg aattttaaca aaatattaac
gtttacaatt 2520ttatggtgca ctctcagtac aatctgctct gatgccgcat
agttaagcca gccccgacac 2580ccgccaacac ccgctgacgc gccctgacgg
gcttgtctgc tcccggcatc cgcttacaga 2640caagctgtga ccgtctccgg
gagctgcatg tgtcagaggt tttcaccgtc atcaccgaaa 2700cgcgcgagac
gaaagggcct cgtgatacgc ctatttttat aggttaatgt catgataata
2760atggtttctt agacgtcagg tggcactttt cggggaaatg tgcgcggaac
ccctatttgt 2820ttatttttct aaatacattc aaatatgtat ccgctcatga
gacaataacc ctgataaatg 2880cttcaataat attgaaaaag gaagagtatg
agtattcaac atttccgtgt cgcccttatt 2940cccttttttg cggcattttg
ccttcctgtt tttgctcacc cagaaacgct ggtgaaagta 3000aaagatgctg
aagatcagtt gggtgcacga gtgggttaca tcgaactgga tctcaacagc
3060ggtaagatcc ttgagagttt tcgccccgaa gaacgttttc caatgatgag
cacttttaaa 3120gttctgctat gtggcgcggt attatcccgt attgacgccg
ggcaagagca actcggtcgc 3180cgcatacact attctcagaa tgacttggtt
gagtactcac cagtcacaga aaagcatctt 3240acggatggca tgacagtaag
agaattatgc agtgctgcca taaccatgag tgataacact 3300gcggccaact
tacttctgac aacgatcgga ggaccgaagg agctaaccgc ttttttgcac
3360aacatggggg atcatgtaac tcgccttgat cgttgggaac cggagctgaa
tgaagccata 3420ccaaacgacg agcgtgacac cacgatgcct gtagcaatgg
caacaacgtt gcgcaaacta 3480ttaactggcg aactacttac tctagcttcc
cggcaacaat taatagactg gatggaggcg 3540gataaagttg caggaccact
tctgcgctcg gcccttccgg ctggctggtt tattgctgat 3600aaatctggag
ccggtgagcg tgggtctcgc ggtatcattg cagcactggg gccagatggt
3660aagccctccc gtatcgtagt tatctacacg acggggagtc aggcaactat
ggatgaacga 3720aatagacaga tcgctgagat aggtgcctca ctgattaagc
attggtaact gtcagaccaa 3780gtttactcat atatacttta gattgattta
aaacttcatt tttaatttaa aaggatctag 3840gtgaagatcc tttttgataa
tctcatgacc aaaatccctt aacgtgagtt ttcgttccac 3900tgagcgtcag
accccgtaga aaagatcaaa ggatcttctt gagatccttt ttttctgcgc
3960gtaatctgct gcttgcaaac aaaaaaacca ccgctaccag cggtggtttg
tttgccggat 4020caagagctac caactctttt tccgaaggta actggcttca
gcagagcgca gataccaaat 4080actgtccttc tagtgtagcc gtagttaggc
caccacttca agaactctgt agcaccgcct 4140acatacctcg ctctgctaat
cctgttacca gtggctgctg ccagtggcga taagtcgtgt 4200cttaccgggt
tggactcaag acgatagtta ccggataagg cgcagcggtc gggctgaacg
4260gggggttcgt gcacacagcc cagcttggag cgaacgacct acaccgaact
gagataccta 4320cagcgtgagc tatgagaaag cgccacgctt cccgaaggga
gaaaggcgga caggtatccg 4380gtaagcggca gggtcggaac aggagagcgc
acgagggagc ttccaggggg aaacgcctgg 4440tatctttata gtcctgtcgg
gtttcgccac ctctgacttg agcgtcgatt tttgtgatgc 4500tcgtcagggg
ggcggagcct atggaaaaac gccagcaacg cggccttttt acggttcctg
4560gccttttgct ggccttttgc tcacatgttc tttcctgcgt tatcccctga
ttctgtggat 4620aaccgtatta ccgcctttga gtgagctgat accgctcgcc
gcagccgaac gaccgagcgc 4680agcgagtcag tgagcgagga agcggaagag
cgcccaatac gcaaaccgcc tctccccgcg 4740cgttggccga ttcattaatg
cagctggcac gacaggtttc ccgactggaa agcgggcagt 4800gagcgcaacg
caattaatgt gagttagctc actcattagg caccccaggc tttacacttt
4860atgcttccgg ctcgtatgtt gtgtggaatt gtgagcggat aacaatttca
cacaggaaac 4920agctatgacc atgattacgc c 494115624DNAArtificial
sequenceAnti-sense primer HuCIgG 156gtccaccttg gtgttgctgg gctt
24157741DNAArtificial sequenceSC04-001 157gcc atg gcc gag gtg cag
ctg gtg gag tct ggg gga ggt gtg gta cgg 48Ala Met Ala Glu Val Gln
Leu Val Glu Ser Gly Gly Gly Val Val Arg1 5 10 15cct ggg ggg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttt 96Pro Gly Gly Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30gat gat tat ggc
atg agc tgg gtc cgc caa gct cca ggg aag ggg ctg 144Asp Asp Tyr Gly
Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtc
tct ggt att aat tgg aat ggt ggt agc aca ggt tat gca 192Glu Trp Val
Ser Gly Ile Asn Trp Asn Gly Gly Ser Thr Gly Tyr Ala 50 55 60gac tct
gtg aag ggc cga ttc acc atc tcc aga gac aac gcc aag aac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ala Lys Asn65 70 75
80tcc ctg tat ctg caa atg aac agt ctg aga gcc gag gac acg gcc gtg
288Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gca aag ggc ctt tat ggg gag ctt ttt gac tac tgg
ggc 336Tyr Tyr Cys Ala Lys Gly Leu Tyr Gly Glu Leu Phe Asp Tyr Trp
Gly 100 105 110caa ggt acc ctg gtc acc gtc tcg aga ggt gga ggc ggt
tca ggc gga 384Gln Gly Thr Leu Val Thr Val Ser Arg Gly Gly Gly Gly
Ser Gly Gly 115 120 125ggt ggc tct ggc ggt ggc gga tcg tct gag ctg
act cag gac cct gct 432Gly Gly Ser Gly Gly Gly Gly Ser Ser Glu Leu
Thr Gln Asp Pro Ala 130 135 140gtg tct gtg gcc ttg gga cag aca gtc
agg atc aca tgc caa gga gac 480Val Ser Val Ala Leu Gly Gln Thr Val
Arg Ile Thr Cys Gln Gly Asp145 150 155 160agc ctc aga agc tat tat
gca agc tgg tac cag cag aag cca gga cag 528Ser Leu Arg Ser Tyr Tyr
Ala Ser Trp Tyr Gln Gln Lys Pro Gly Gln 165 170 175gcc cct gta ctt
gtc atc tat ggt aaa aac aac cgg ccc tca ggg atc 576Ala Pro Val Leu
Val Ile Tyr Gly Lys Asn Asn Arg Pro Ser Gly Ile 180 185 190cca gac
cga ttc tct ggc tcc agc tca gga aac aca gct tcc ttg acc 624Pro Asp
Arg Phe Ser Gly Ser Ser Ser Gly Asn Thr Ala Ser Leu Thr 195 200
205atc act ggg gct cag gcg gaa gat gag gct gac tat tac tgt aac tcc
672Ile Thr Gly Ala Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Asn Ser
210 215 220cgg gac agc agt ggt aac cat gtg gta ttc ggc gga ggg acc
aag ctg 720Arg Asp Ser Ser Gly Asn His Val Val Phe Gly Gly Gly Thr
Lys Leu225 230 235 240acc gtc cta ggt gcg gcc gca 741Thr Val Leu
Gly Ala Ala Ala 245158247PRTArtificial sequenceSynthetic Construct
158Ala Met Ala Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Arg1
5 10 15Pro Gly Gly Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe 20 25 30Asp Asp Tyr Gly Met Ser Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu 35 40 45Glu Trp Val Ser Gly Ile Asn Trp Asn Gly Gly Ser Thr
Gly Tyr Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ala Lys Asn65 70 75 80Ser Leu Tyr Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly Leu Tyr Gly
Glu Leu Phe Asp Tyr Trp Gly 100 105 110Gln Gly Thr Leu Val Thr Val
Ser Arg Gly Gly Gly Gly Ser Gly Gly 115 120 125Gly Gly Ser Gly Gly
Gly Gly Ser Ser Glu Leu Thr Gln Asp Pro Ala 130 135 140Val Ser Val
Ala Leu Gly Gln Thr Val Arg Ile Thr Cys Gln Gly Asp145 150 155
160Ser Leu Arg Ser Tyr Tyr Ala Ser Trp Tyr Gln Gln Lys Pro Gly Gln
165 170 175Ala Pro Val Leu Val Ile Tyr Gly Lys Asn Asn Arg Pro Ser
Gly Ile 180 185 190Pro Asp Arg Phe Ser Gly Ser Ser Ser Gly Asn Thr
Ala Ser Leu Thr 195 200 205Ile Thr Gly Ala Gln Ala Glu Asp Glu Ala
Asp Tyr Tyr Cys Asn Ser 210 215 220Arg Asp Ser Ser Gly Asn His Val
Val Phe Gly Gly Gly Thr Lys Leu225 230 235 240Thr Val Leu Gly Ala
Ala Ala 245159741DNAArtificial sequenceSC04-004 159tcc atg gct gag
gtg cag ctg gtg gag tct ggg gga ggc ttg gtc cag 48Ser Met Ala Glu
Val Gln Leu Val Glu Ser Gly Gly Gly Leu Val Gln1 5 10 15cct ggg ggg
tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Gly
Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agc aac
tac tgg atg aac tgg gtc cgc cag gcg ccc ggg aag ggg ctg 144Ser Asn
Tyr Trp Met Asn Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag
tgg gtc tca gct att agt ggt agt ggt ggt agc aca tac tac gca 192Glu
Trp Val Ser Ala Ile Ser Gly Ser Gly Gly Ser Thr Tyr Tyr Ala 50 55
60gac tcc gtg aag ggc cgg ttc acc atc tcc aga gac aat tcc aag aac
240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80acg ctg tat ctg caa atg aac agc ctg aga gcc gag gac
acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95tat tac tgt gcc aaa gac tac ctc tac ccc acc acc
gac ttc gat tac 336Tyr Tyr Cys Ala Lys Asp Tyr Leu Tyr Pro Thr Thr
Asp Phe Asp Tyr 100 105 110tgg ggc cag ggc acc ctg gtg acc gtg ctc
gag ggt acc gga ggt tcc 384Trp Gly Gln Gly Thr Leu Val Thr Val Leu
Glu Gly Thr Gly Gly Ser 115 120 125ggc gga acc ggg tct ggg act ggt
acg agc gag ctc acc cag tct cca 432Gly Gly Thr Gly Ser Gly Thr Gly
Thr Ser Glu Leu Thr Gln Ser Pro 130 135 140tcc tcc ctg tct gca tct
gta gga gac aga gtc acc atc act tgc cgg 480Ser Ser Leu Ser Ala Ser
Val Gly Asp Arg Val Thr Ile Thr Cys Arg145 150 155 160gca agt cag
agc att agc agc tac tta aat tgg tat cag cag aaa cca 528Ala Ser Gln
Ser Ile Ser Ser Tyr Leu Asn Trp Tyr Gln Gln Lys Pro 165 170 175ggg
aaa gcc cct aag ctc ctg atc tat gct gca tcc agt ttg caa agt 576Gly
Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu Gln Ser 180 185
190ggg gtc cca tca agg ttc agt ggc agt gga tct ggg aca gat ttc act
624Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe Thr
195 200 205ctc acc atc agc agt ctg caa cct gaa gat ttt gca act tac
tac tgt 672Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr
Tyr Cys 210 215 220caa cag agt tac agt acc cct cca acg ttc ggc caa
ggg acc aag gtg 720Gln Gln Ser Tyr Ser Thr Pro Pro Thr Phe Gly Gln
Gly Thr Lys Val225 230 235 240gag atc aaa cgt gcg gcc gca 741Glu
Ile Lys Arg Ala Ala Ala 245160247PRTArtificial sequenceSynthetic
Construct 160Ser Met Ala Glu Val Gln Leu Val Glu Ser Gly Gly Gly
Leu Val Gln1 5 10 15Pro Gly Gly Ser Leu Arg Leu Ser Cys Ala Ala Ser
Gly Phe Thr Phe 20 25 30Ser Asn Tyr Trp Met Asn Trp Val Arg Gln Ala
Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ser Ala Ile Ser Gly Ser Gly
Gly Ser Thr Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile
Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn
Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Asp
Tyr Leu Tyr Pro Thr Thr Asp Phe Asp Tyr 100 105 110Trp Gly Gln Gly
Thr Leu Val Thr Val Leu Glu Gly Thr Gly Gly Ser 115 120 125Gly Gly
Thr Gly Ser Gly Thr Gly Thr Ser Glu Leu Thr Gln Ser Pro 130 135
140Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr Cys
Arg145 150 155 160Ala Ser Gln Ser Ile Ser Ser Tyr Leu Asn Trp Tyr
Gln Gln Lys Pro 165 170 175Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala
Ala Ser Ser Leu Gln Ser 180 185 190Gly Val Pro Ser Arg Phe Ser Gly
Ser Gly Ser Gly Thr Asp Phe Thr 195 200 205Leu Thr Ile Ser Ser Leu
Gln Pro Glu Asp Phe Ala Thr Tyr Tyr Cys 210 215 220Gln Gln Ser Tyr
Ser Thr Pro Pro Thr Phe Gly Gln Gly Thr Lys Val225 230 235 240Glu
Ile Lys Arg Ala Ala Ala
245161756DNAArtificial sequenceSC04-008 161gcc atg gcc cag gtc acc
ttg aag gag tct ggt cct acg ctg gtg aaa 48Ala Met Ala Gln Val Thr
Leu Lys Glu Ser Gly Pro Thr Leu Val Lys1 5 10 15ccc aca cag acc ctc
acg ctg acc tgc acc ttc tct ggg ttc tca ctc 96Pro Thr Gln Thr Leu
Thr Leu Thr Cys Thr Phe Ser Gly Phe Ser Leu 20 25 30agc act agt gga
gtg ggt gtg ggc tgg atc cgt cag ccc cca gga aag 144Ser Thr Ser Gly
Val Gly Val Gly Trp Ile Arg Gln Pro Pro Gly Lys 35 40 45gcc ctg gag
tgg ctt gca cgc att gat tgg gat gat gat aaa tac tac 192Ala Leu Glu
Trp Leu Ala Arg Ile Asp Trp Asp Asp Asp Lys Tyr Tyr 50 55 60agc aca
tct ctg aag acc agg ctc acc atc tcc aag gac acc tcc aaa 240Ser Thr
Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Asp Thr Ser Lys65 70 75
80aac cag gtg gtc ctt aca atg acc aac atg gac cct gtg gac aca gcc
288Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala
85 90 95acg tat tac tgt gca cgg atg ggt ttc act gga acc tac ttt gac
tac 336Thr Tyr Tyr Cys Ala Arg Met Gly Phe Thr Gly Thr Tyr Phe Asp
Tyr 100 105 110tgg ggc cag ggc acc ctg gtc acc gtc tcg agc ggt acg
ggc ggt tca 384Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr
Gly Gly Ser 115 120 125ggc gga acc ggc agc ggc act ggc ggg tcg acg
cag gct gtg ctg act 432Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr
Gln Ala Val Leu Thr 130 135 140cag ccg tcc tcg gtg tca gtg gcc cca
gga gag acg gcc agc gtt acc 480Gln Pro Ser Ser Val Ser Val Ala Pro
Gly Glu Thr Ala Ser Val Thr145 150 155 160tgt ggg gga gac aac att
ggg agt aag agt gtg cac tgg tac caa aag 528Cys Gly Gly Asp Asn Ile
Gly Ser Lys Ser Val His Trp Tyr Gln Lys 165 170 175aag cca ggc cag
gcc cct gtg ctg gtc gtc ttt gat gat agc gac cgg 576Lys Pro Gly Gln
Ala Pro Val Leu Val Val Phe Asp Asp Ser Asp Arg 180 185 190ccc tca
ggg atc cct gag cga ttc tct ggc tcc acc tct ggg aac acg 624Pro Ser
Gly Ile Pro Glu Arg Phe Ser Gly Ser Thr Ser Gly Asn Thr 195 200
205gcc gcc ctg acc atc agc agg gtc gaa gcc ggg gat gag gcc gac tat
672Ala Ala Leu Thr Ile Ser Arg Val Glu Ala Gly Asp Glu Ala Asp Tyr
210 215 220tac tgt cag gtg tgg gat agt agt aat gat cat ctt tat gtc
ttc gga 720Tyr Cys Gln Val Trp Asp Ser Ser Asn Asp His Leu Tyr Val
Phe Gly225 230 235 240ccc ggg acc cag ctc acc gtt tta agt gcg gcc
gca 756Pro Gly Thr Gln Leu Thr Val Leu Ser Ala Ala Ala 245
250162252PRTArtificial sequenceSynthetic Construct 162Ala Met Ala
Gln Val Thr Leu Lys Glu Ser Gly Pro Thr Leu Val Lys1 5 10 15Pro Thr
Gln Thr Leu Thr Leu Thr Cys Thr Phe Ser Gly Phe Ser Leu 20 25 30Ser
Thr Ser Gly Val Gly Val Gly Trp Ile Arg Gln Pro Pro Gly Lys 35 40
45Ala Leu Glu Trp Leu Ala Arg Ile Asp Trp Asp Asp Asp Lys Tyr Tyr
50 55 60Ser Thr Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Asp Thr Ser
Lys65 70 75 80Asn Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val
Asp Thr Ala 85 90 95Thr Tyr Tyr Cys Ala Arg Met Gly Phe Thr Gly Thr
Tyr Phe Asp Tyr 100 105 110Trp Gly Gln Gly Thr Leu Val Thr Val Ser
Ser Gly Thr Gly Gly Ser 115 120 125Gly Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Gln Ala Val Leu Thr 130 135 140Gln Pro Ser Ser Val Ser
Val Ala Pro Gly Glu Thr Ala Ser Val Thr145 150 155 160Cys Gly Gly
Asp Asn Ile Gly Ser Lys Ser Val His Trp Tyr Gln Lys 165 170 175Lys
Pro Gly Gln Ala Pro Val Leu Val Val Phe Asp Asp Ser Asp Arg 180 185
190Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser Thr Ser Gly Asn Thr
195 200 205Ala Ala Leu Thr Ile Ser Arg Val Glu Ala Gly Asp Glu Ala
Asp Tyr 210 215 220Tyr Cys Gln Val Trp Asp Ser Ser Asn Asp His Leu
Tyr Val Phe Gly225 230 235 240Pro Gly Thr Gln Leu Thr Val Leu Ser
Ala Ala Ala 245 250163759DNAArtificial sequenceSC04-010 163gcc atg
gcc cag gtg cag ctg gtg cag tct ggg gga gac ttg gtc cag 48Ala Met
Ala Gln Val Gln Leu Val Gln Ser Gly Gly Asp Leu Val Gln1 5 10 15cct
ggg agg tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro
Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25
30agt agc tat ggc atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg
144Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu
35 40 45gag tgg gtg gca gat ata tca tat gat gga agt aat aaa tac tat
gca 192Glu Trp Val Ala Asp Ile Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr
Ala 50 55 60gac tcc gtg aag ggc cga ttc acc att tcc aga gac aat tcc
aag aac 240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser
Lys Asn65 70 75 80acg ctg tat ctg caa atg aac agc ctg aga gct gag
gac acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu
Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa gat ggg ctg gat tta act
gga acg att cag cca 336Tyr Tyr Cys Ala Lys Asp Gly Leu Asp Leu Thr
Gly Thr Ile Gln Pro 100 105 110ttt ggc tac tgg ggc cag gga acc ctg
gtc acc gtc tcg agc ggt acg 384Phe Gly Tyr Trp Gly Gln Gly Thr Leu
Val Thr Val Ser Ser Gly Thr 115 120 125ggc ggt tca ggc gga acc ggc
agc ggc act ggc ggg tcg acg gac atc 432Gly Gly Ser Gly Gly Thr Gly
Ser Gly Thr Gly Gly Ser Thr Asp Ile 130 135 140cag atg acc cag tct
cca tcc tcc ctg tct gca tct gta gga gac aga 480Gln Met Thr Gln Ser
Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg145 150 155 160gtc acc
atc act tgc cgg gca agt cag ggc att aga aat gat tta ggc 528Val Thr
Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Asp Leu Gly 165 170
175tgg tat cag cag aaa cca ggg aaa gcc cct aag ctc ctg atc tat gct
576Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala
180 185 190gca tcc agt tta caa agt ggg gtc cca tca agg ttc agc ggc
agt gga 624Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly
Ser Gly 195 200 205tct ggc aca gat ttc act ctc acc atc agc agc ctg
cag cct gaa gat 672Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu
Gln Pro Glu Asp 210 215 220ttt gca act tat tac tgt cta caa gat tac
aat tac cct cgg acg ttc 720Phe Ala Thr Tyr Tyr Cys Leu Gln Asp Tyr
Asn Tyr Pro Arg Thr Phe225 230 235 240ggc caa ggg acc aag gtg gag
atc aaa cgt gcg gcc gca 759Gly Gln Gly Thr Lys Val Glu Ile Lys Arg
Ala Ala Ala 245 250164253PRTArtificial sequenceSynthetic Construct
164Ala Met Ala Gln Val Gln Leu Val Gln Ser Gly Gly Asp Leu Val Gln1
5 10 15Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe 20 25 30Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu 35 40 45Glu Trp Val Ala Asp Ile Ser Tyr Asp Gly Ser Asn Lys
Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Asp Gly Leu Asp
Leu Thr Gly Thr Ile Gln Pro 100 105 110Phe Gly Tyr Trp Gly Gln Gly
Thr Leu Val Thr Val Ser Ser Gly Thr 115 120 125Gly Gly Ser Gly Gly
Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile 130 135 140Gln Met Thr
Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg145 150 155
160Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile Arg Asn Asp Leu Gly
165 170 175Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile
Tyr Ala 180 185 190Ala Ser Ser Leu Gln Ser Gly Val Pro Ser Arg Phe
Ser Gly Ser Gly 195 200 205Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser
Ser Leu Gln Pro Glu Asp 210 215 220Phe Ala Thr Tyr Tyr Cys Leu Gln
Asp Tyr Asn Tyr Pro Arg Thr Phe225 230 235 240Gly Gln Gly Thr Lys
Val Glu Ile Lys Arg Ala Ala Ala 245 250165756DNAArtificial
sequenceSC04-018 165gcc atg gcc gag gtg cag ctg gtg gag tct ggc cca
gga ctg gtg agg 48Ala Met Ala Glu Val Gln Leu Val Glu Ser Gly Pro
Gly Leu Val Arg1 5 10 15cct tcg ggg acc ctg tcc ctc acc tgc gct gtc
tct ggt ggc tcc atc 96Pro Ser Gly Thr Leu Ser Leu Thr Cys Ala Val
Ser Gly Gly Ser Ile 20 25 30agc agt agt aac tgg tgg agt tgg gtc cgc
cag ccc cca ggg aag ggg 144Ser Ser Ser Asn Trp Trp Ser Trp Val Arg
Gln Pro Pro Gly Lys Gly 35 40 45ctg gag tgg att ggg gaa atc tat cat
agt ggg agc acc aac tac aac 192Leu Glu Trp Ile Gly Glu Ile Tyr His
Ser Gly Ser Thr Asn Tyr Asn 50 55 60ccg tcc ctc aag agt cga gtc acc
ata tca gta gac aag tcc aag aac 240Pro Ser Leu Lys Ser Arg Val Thr
Ile Ser Val Asp Lys Ser Lys Asn65 70 75 80cag ttc tcc ctg aag ctg
agc tct gtg acc gcc gcg gac acg gcc gtg 288Gln Phe Ser Leu Lys Leu
Ser Ser Val Thr Ala Ala Asp Thr Ala Val 85 90 95tat tac tgt gcg aga
gtt tct gtg act acg ggt gct ttt aat atc tgg 336Tyr Tyr Cys Ala Arg
Val Ser Val Thr Thr Gly Ala Phe Asn Ile Trp 100 105 110ggc caa ggg
aca atg gtc acc gtc tcg agc ggt acg ggc ggt tca ggc 384Gly Gln Gly
Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly 115 120 125gga
acc ggc agc ggc act ggc ggg tcg acg cag cct gtg ctg act cag 432Gly
Thr Gly Ser Gly Thr Gly Gly Ser Thr Gln Pro Val Leu Thr Gln 130 135
140ccc ctc tca gcg tct ggg acc ccc ggg cag agg gtc acc atc tct tgt
480Pro Leu Ser Ala Ser Gly Thr Pro Gly Gln Arg Val Thr Ile Ser
Cys145 150 155 160tct gga gac acc tcc aac atc gga agt aat act gta
cac tgg tac cag 528Ser Gly Asp Thr Ser Asn Ile Gly Ser Asn Thr Val
His Trp Tyr Gln 165 170 175cgc ctc cca gga acg gcc ccc aaa ctc ctc
atc cat aat aat aat cag 576Arg Leu Pro Gly Thr Ala Pro Lys Leu Leu
Ile His Asn Asn Asn Gln 180 185 190cgg ccc tca ggg gtc cct gac cgg
ttc tct ggc gcc aag tct ggc acc 624Arg Pro Ser Gly Val Pro Asp Arg
Phe Ser Gly Ala Lys Ser Gly Thr 195 200 205tca gcc tcc ctg gcc atc
agt ggg ctc cag tct gag gat gag gct gat 672Ser Ala Ser Leu Ala Ile
Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp 210 215 220tat ttc tgt gca
gca tgg gat gac aac ctg aat ggt tat gtc ttc gga 720Tyr Phe Cys Ala
Ala Trp Asp Asp Asn Leu Asn Gly Tyr Val Phe Gly225 230 235 240act
ggg acc aag gtc acc gtc cta ggt gcg gcc gca 756Thr Gly Thr Lys Val
Thr Val Leu Gly Ala Ala Ala 245 250166252PRTArtificial
sequenceSynthetic Construct 166Ala Met Ala Glu Val Gln Leu Val Glu
Ser Gly Pro Gly Leu Val Arg1 5 10 15Pro Ser Gly Thr Leu Ser Leu Thr
Cys Ala Val Ser Gly Gly Ser Ile 20 25 30Ser Ser Ser Asn Trp Trp Ser
Trp Val Arg Gln Pro Pro Gly Lys Gly 35 40 45Leu Glu Trp Ile Gly Glu
Ile Tyr His Ser Gly Ser Thr Asn Tyr Asn 50 55 60Pro Ser Leu Lys Ser
Arg Val Thr Ile Ser Val Asp Lys Ser Lys Asn65 70 75 80Gln Phe Ser
Leu Lys Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Arg Val Ser Val Thr Thr Gly Ala Phe Asn Ile Trp 100 105
110Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly
115 120 125Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Gln Pro Val Leu
Thr Gln 130 135 140Pro Leu Ser Ala Ser Gly Thr Pro Gly Gln Arg Val
Thr Ile Ser Cys145 150 155 160Ser Gly Asp Thr Ser Asn Ile Gly Ser
Asn Thr Val His Trp Tyr Gln 165 170 175Arg Leu Pro Gly Thr Ala Pro
Lys Leu Leu Ile His Asn Asn Asn Gln 180 185 190Arg Pro Ser Gly Val
Pro Asp Arg Phe Ser Gly Ala Lys Ser Gly Thr 195 200 205Ser Ala Ser
Leu Ala Ile Ser Gly Leu Gln Ser Glu Asp Glu Ala Asp 210 215 220Tyr
Phe Cys Ala Ala Trp Asp Asp Asn Leu Asn Gly Tyr Val Phe Gly225 230
235 240Thr Gly Thr Lys Val Thr Val Leu Gly Ala Ala Ala 245
250167747DNAArtificial sequenceSC04-021 167gcc atg gcc gag gtg cag
ctg gtg gag tct ggg gga ggc gtg gtc cag 48Ala Met Ala Glu Val Gln
Leu Val Glu Ser Gly Gly Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc
atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly
Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg
gca gtt ata tca tat gat gga agt agt aaa tat tat gca 192Glu Trp Val
Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys Tyr Tyr Ala 50 55 60gac tcc
gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac acg gct gtg
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa ggg tcc gtc ctc ggt gat gct ttt gat atc
tgg 336Tyr Tyr Cys Ala Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile
Trp 100 105 110ggc caa ggg aca atg gtc acc gtc tcg agc ggt acg ggc
ggt tca ggc 384Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly
Gly Ser Gly 115 120 125gga acc ggc agc ggc act ggc ggg tcg acg gac
atc cag atg acc cag 432Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp
Ile Gln Met Thr Gln 130 135 140tct cca ttc tcc ctg tct gct tct gtc
gga gac aga gtt acc atc act 480Ser Pro Phe Ser Leu Ser Ala Ser Val
Gly Asp Arg Val Thr Ile Thr145 150 155 160tgc cgg gcc agt cag ggc
att ggc agt tcc tta gcc tgg tat cag caa 528Cys Arg Ala Ser Gln Gly
Ile Gly Ser Ser Leu Ala Trp Tyr Gln Gln 165 170 175aaa cca ggg aaa
gcc cct aaa ctc ctg atc tac gct gca tcc agt ttg 576Lys Pro Gly Lys
Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185 190caa agt
ggg gtc cca tca agg ttc agc ggc agt gga tct ggg aca gat 624Gln Ser
Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200
205ttc act ctc acc atc agc agc ctg cag cct gaa gat ttt gca act tat
672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr
210 215 220ttc tgt ctg cag cat cat gat tac ccg ctc act ttc ggc gga
ggg acc 720Phe Cys Leu Gln His His Asp Tyr Pro Leu Thr Phe Gly Gly
Gly Thr225 230 235 240aag ctg gag atc aaa cgt gcg gcc gca 747Lys
Leu Glu Ile Lys Arg Ala Ala Ala 245168249PRTArtificial
sequenceSynthetic Construct 168Ala Met Ala Glu Val Gln Leu Val Glu
Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu
35 40 45Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys Tyr Tyr
Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser
Lys Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu
Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly Ser Val Leu Gly Asp
Ala Phe Asp Ile Trp 100 105 110Gly Gln Gly Thr Met Val Thr Val Ser
Ser Gly Thr Gly Gly Ser Gly 115 120 125Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Asp Ile Gln Met Thr Gln 130 135 140Ser Pro Phe Ser Leu
Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160Cys Arg
Ala Ser Gln Gly Ile Gly Ser Ser Leu Ala Trp Tyr Gln Gln 165 170
175Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu
180 185 190Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly
Thr Asp 195 200 205Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp
Phe Ala Thr Tyr 210 215 220Phe Cys Leu Gln His His Asp Tyr Pro Leu
Thr Phe Gly Gly Gly Thr225 230 235 240Lys Leu Glu Ile Lys Arg Ala
Ala Ala 245169768DNAArtificial sequenceSC04-026 169gcc atg gcc gag
gtg cag ctg gtg gag tct gga gca gag gtg aag aag 48Ala Met Ala Glu
Val Gln Leu Val Glu Ser Gly Ala Glu Val Lys Lys1 5 10 15ccg ggg gaa
tct ctg aag atc tcc tgt aag ggt tct gga tac aac ttt 96Pro Gly Glu
Ser Leu Lys Ile Ser Cys Lys Gly Ser Gly Tyr Asn Phe 20 25 30ccc tac
tcc tgg atc gcc tgg gtg cgc cag atg ccc ggg aaa ggc ctg 144Pro Tyr
Ser Trp Ile Ala Trp Val Arg Gln Met Pro Gly Lys Gly Leu 35 40 45gag
tgg atg ggg atc atc ttt cct ggt gac tct gac acc aga tat agt 192Glu
Trp Met Gly Ile Ile Phe Pro Gly Asp Ser Asp Thr Arg Tyr Ser 50 55
60ccg ccc ttc caa ggc cag gtc acc atc tca gcc gac aac tcc aaa agc
240Pro Pro Phe Gln Gly Gln Val Thr Ile Ser Ala Asp Asn Ser Lys
Ser65 70 75 80acc gcc tac ctg cag tgg agt agc ctg aag gcc tcg gac
acc gcc atg 288Thr Ala Tyr Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp
Thr Ala Met 85 90 95tat tac tgt gcg cgg acc tcg aac tgg aac tat ttg
gac cgg ttc gac 336Tyr Tyr Cys Ala Arg Thr Ser Asn Trp Asn Tyr Leu
Asp Arg Phe Asp 100 105 110ccc tgg ggc cag ggc acc ctg gtc acc gtc
tcg agc ggt acg ggc ggt 384Pro Trp Gly Gln Gly Thr Leu Val Thr Val
Ser Ser Gly Thr Gly Gly 115 120 125tca ggc gga acc ggc agc ggc act
ggc ggg tcg acg gat gtt gtg atg 432Ser Gly Gly Thr Gly Ser Gly Thr
Gly Gly Ser Thr Asp Val Val Met 130 135 140act cag tct cca ctc tcc
ctg ccc gtc acc cct gga gag ccg gcc tcc 480Thr Gln Ser Pro Leu Ser
Leu Pro Val Thr Pro Gly Glu Pro Ala Ser145 150 155 160atc tcc tgc
agg tct agt cag agc ctc ctg cat agt aat gga cat gat 528Ile Ser Cys
Arg Ser Ser Gln Ser Leu Leu His Ser Asn Gly His Asp 165 170 175tac
ttg gat tgg tac gtg cag aag cca ggg cag tct cca cag ccc ctg 576Tyr
Leu Asp Trp Tyr Val Gln Lys Pro Gly Gln Ser Pro Gln Pro Leu 180 185
190atc tat ttg ggt tct gat cgg gcc tcc ggg gtc cct gac agg ttc agt
624Ile Tyr Leu Gly Ser Asp Arg Ala Ser Gly Val Pro Asp Arg Phe Ser
195 200 205ggc agt gga tca ggc aca cat ttt aca ctg aat atc agc aga
gtg gag 672Gly Ser Gly Ser Gly Thr His Phe Thr Leu Asn Ile Ser Arg
Val Glu 210 215 220gct gag gat gtt ggg gtt tat tac tgc atg caa tct
cta caa act cct 720Ala Glu Asp Val Gly Val Tyr Tyr Cys Met Gln Ser
Leu Gln Thr Pro225 230 235 240tgg act ttt ggc cag ggg acc aag ctg
gag atc aaa cgt gcg gcc gca 768Trp Thr Phe Gly Gln Gly Thr Lys Leu
Glu Ile Lys Arg Ala Ala Ala 245 250 255170256PRTArtificial
sequenceSynthetic Construct 170Ala Met Ala Glu Val Gln Leu Val Glu
Ser Gly Ala Glu Val Lys Lys1 5 10 15Pro Gly Glu Ser Leu Lys Ile Ser
Cys Lys Gly Ser Gly Tyr Asn Phe 20 25 30Pro Tyr Ser Trp Ile Ala Trp
Val Arg Gln Met Pro Gly Lys Gly Leu 35 40 45Glu Trp Met Gly Ile Ile
Phe Pro Gly Asp Ser Asp Thr Arg Tyr Ser 50 55 60Pro Pro Phe Gln Gly
Gln Val Thr Ile Ser Ala Asp Asn Ser Lys Ser65 70 75 80Thr Ala Tyr
Leu Gln Trp Ser Ser Leu Lys Ala Ser Asp Thr Ala Met 85 90 95Tyr Tyr
Cys Ala Arg Thr Ser Asn Trp Asn Tyr Leu Asp Arg Phe Asp 100 105
110Pro Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr Gly Gly
115 120 125Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Val
Val Met 130 135 140Thr Gln Ser Pro Leu Ser Leu Pro Val Thr Pro Gly
Glu Pro Ala Ser145 150 155 160Ile Ser Cys Arg Ser Ser Gln Ser Leu
Leu His Ser Asn Gly His Asp 165 170 175Tyr Leu Asp Trp Tyr Val Gln
Lys Pro Gly Gln Ser Pro Gln Pro Leu 180 185 190Ile Tyr Leu Gly Ser
Asp Arg Ala Ser Gly Val Pro Asp Arg Phe Ser 195 200 205Gly Ser Gly
Ser Gly Thr His Phe Thr Leu Asn Ile Ser Arg Val Glu 210 215 220Ala
Glu Asp Val Gly Val Tyr Tyr Cys Met Gln Ser Leu Gln Thr Pro225 230
235 240Trp Thr Phe Gly Gln Gly Thr Lys Leu Glu Ile Lys Arg Ala Ala
Ala 245 250 255171747DNAArtificial sequenceSC04-031 171gcc atg gcc
gag gtg cag ctg gtg gag tct ggg gga ggc gtg gtc cag 48Ala Met Ala
Glu Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln1 5 10 15cct ggg
agg tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly
Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt
agc tat ggc atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45gag tgg gtg gca gtt ata tca tat gat gga agt aat aaa tac tat gca
192Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala
50 55 60gac tcc gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag
aac 240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac
acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95tat tac tgt gcg aaa ggg tcc gtc ctc ggt gat gct
ttt gat atc tgg 336Tyr Tyr Cys Ala Lys Gly Ser Val Leu Gly Asp Ala
Phe Asp Ile Trp 100 105 110ggc caa ggg aca atg gtc acc gtc tcg agc
ggt acg ggc ggt tca ggc 384Gly Gln Gly Thr Met Val Thr Val Ser Ser
Gly Thr Gly Gly Ser Gly 115 120 125gga acc ggc agc ggc act ggc ggg
tcg acg gac atc cag atg acc cag 432Gly Thr Gly Ser Gly Thr Gly Gly
Ser Thr Asp Ile Gln Met Thr Gln 130 135 140tct cca tct ttc gtg tct
gca tct gta gga gac aga gtc acc atc act 480Ser Pro Ser Phe Val Ser
Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160tgt cgg gcg
agt cag ggt att agc agt tgg tta gcc tgg tat cag cag 528Cys Arg Ala
Ser Gln Gly Ile Ser Ser Trp Leu Ala Trp Tyr Gln Gln 165 170 175aaa
cca ggg aaa gcc cct aag ctc ctg atc tat gct gca tcc agt ttg 576Lys
Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185
190caa agt ggg gtc cca tca agg ttc agc ggc agt gga tct ggg aca gat
624Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp
195 200 205ttc act ctc acc atc agc agc ctg cag cct gaa gat ttt gca
act tac 672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala
Thr Tyr 210 215 220tat tgt caa cag gct aac agt ttc cca ctc act ttc
ggc gga ggg acc 720Tyr Cys Gln Gln Ala Asn Ser Phe Pro Leu Thr Phe
Gly Gly Gly Thr225 230 235 240aag gtg gag atc aaa cga gcg gcc gca
747Lys Val Glu Ile Lys Arg Ala Ala Ala 245172249PRTArtificial
sequenceSynthetic Construct 172Ala Met Ala Glu Val Gln Leu Val Glu
Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Val Ile
Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile Trp 100 105
110Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly
115 120 125Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Met
Thr Gln 130 135 140Ser Pro Ser Phe Val Ser Ala Ser Val Gly Asp Arg
Val Thr Ile Thr145 150 155 160Cys Arg Ala Ser Gln Gly Ile Ser Ser
Trp Leu Ala Trp Tyr Gln Gln 165 170 175Lys Pro Gly Lys Ala Pro Lys
Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185 190Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200 205Phe Thr Leu
Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr 210 215 220Tyr
Cys Gln Gln Ala Asn Ser Phe Pro Leu Thr Phe Gly Gly Gly Thr225 230
235 240Lys Val Glu Ile Lys Arg Ala Ala Ala 245173747DNAArtificial
sequenceSC04-038 173gcc atg gcc cag gtg cag ctg gtg caa tct ggg gga
ggc gtg gtc cag 48Ala Met Ala Gln Val Gln Leu Val Gln Ser Gly Gly
Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcc
tct gga ttc acc ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala
Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc atg cac tgg gtc cgc cag
gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln
Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg gca gtt ata tca tat gat
gga agt agt aaa tat tat gca 192Glu Trp Val Ala Val Ile Ser Tyr Asp
Gly Ser Ser Lys Tyr Tyr Ala 50 55 60gac tcc gtg aag ggc cga ttc acc
atc tcc aga gac aat tcc aag aac 240Asp Ser Val Lys Gly Arg Phe Thr
Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80acg ctg tat ctg caa atg
aac agc ctg aga gct gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met
Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa
ggg tcc gtc ctc ggt gat gct ttt gat atc tgg 336Tyr Tyr Cys Ala Lys
Gly Ser Val Leu Gly Asp Ala Phe Asp Ile Trp 100 105 110ggc caa ggg
aca atg gtc acc gtc tcg agc ggt acg ggc ggt tca ggc 384Gly Gln Gly
Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly 115 120 125gga
acc ggc agc ggc act ggc ggg tcg acg gac atc cag ttg act cag 432Gly
Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu Thr Gln 130 135
140tct cca tct tcc gtg tct gca tct gta gga gac aga gtc acc atc act
480Ser Pro Ser Ser Val Ser Ala Ser Val Gly Asp Arg Val Thr Ile
Thr145 150 155 160tgt cgg gcg agt cag ggt att agc ggc tgg tta gcc
tgg tat cag cag 528Cys Arg Ala Ser Gln Gly Ile Ser Gly Trp Leu Ala
Trp Tyr Gln Gln 165 170 175aaa cca gag aaa gcc cct aag ctc ctg atc
tat gcg gca tcc agt ttg 576Lys Pro Glu Lys Ala Pro Lys Leu Leu Ile
Tyr Ala Ala Ser Ser Leu 180 185 190caa cgt ggg gtc cca tca agg ttc
agc ggc agt gga tct ggg aca gat 624Gln Arg Gly Val Pro Ser Arg Phe
Ser Gly Ser Gly Ser Gly Thr Asp 195 200 205ttc act ctc acc atc agc
agc ctg cag cct gaa gat ttt gca act tac 672Phe Thr Leu Thr Ile Ser
Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr 210 215 220tat tgt caa cag
gct aac agt ttc ccc ccc acc ttc ggc caa ggg aca 720Tyr Cys Gln Gln
Ala Asn Ser Phe Pro Pro Thr Phe Gly Gln Gly Thr225 230 235 240cga
ctg gag att aaa cgt gcg gcc gca 747Arg Leu Glu Ile Lys Arg Ala Ala
Ala 245174249PRTArtificial sequenceSynthetic Construct 174Ala Met
Ala Gln Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15Pro
Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25
30Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu
35 40 45Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys Tyr Tyr
Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser
Lys Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu
Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly Ser Val Leu Gly Asp
Ala Phe Asp Ile Trp 100 105 110Gly Gln Gly Thr Met Val Thr Val Ser
Ser Gly Thr Gly Gly Ser Gly 115 120 125Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Asp Ile Gln Leu Thr Gln 130 135 140Ser Pro Ser Ser Val
Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160Cys Arg
Ala Ser Gln Gly Ile Ser Gly Trp Leu Ala Trp Tyr Gln Gln 165 170
175Lys Pro Glu Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu
180 185 190Gln Arg Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly
Thr Asp 195 200 205Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp
Phe Ala Thr Tyr 210 215 220Tyr Cys Gln Gln Ala Asn Ser Phe Pro Pro
Thr Phe Gly Gln Gly Thr225 230 235 240Arg Leu Glu Ile Lys Arg Ala
Ala Ala 245175747DNAArtificial sequenceSC04-040 175gcc atg gcc cag
gtg cag ctg gtg cag tct ggg gga ggc gtg gtc cag 48Ala Met Ala Gln
Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15cct ggg agg
tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg
Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30ggt agc
tat ggc atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Gly Ser
Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag
tgg gtg gca act ata ttc tat gat gga agt tat aaa gac tat gca 192Glu
Trp Val Ala Thr Ile Phe Tyr Asp Gly Ser Tyr Lys Asp Tyr Ala 50 55
60gac tcc gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac
240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac
acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95tat tac tgt gcg aaa ggc agt aag gta ggc gac ttt
gac tac tgg ggc 336Tyr Tyr Cys Ala Lys Gly Ser Lys Val Gly Asp Phe
Asp Tyr Trp Gly 100 105 110cag gga acc ctg gtc acc gtc tcg agc ggt
acg ggc ggt tca ggc gga 384Gln Gly Thr Leu Val Thr Val Ser Ser Gly
Thr Gly Gly Ser Gly Gly 115 120 125acc ggc agc ggc act ggc ggg tcg
acg cag cct gtg ctg act cag ccc 432Thr Gly Ser Gly Thr Gly Gly Ser
Thr Gln Pro Val Leu Thr Gln Pro 130 135 140ccc tcg gtg tca gtg gcc
cca gga cag acg gcc agg att tcc tgt ggg 480Pro Ser Val Ser Val Ala
Pro Gly Gln Thr Ala Arg Ile Ser Cys Gly145
150 155 160gga gac aac att gga act aat act gtg cag tgg tac cag cag
aag cca 528Gly Asp Asn Ile Gly Thr Asn Thr Val Gln Trp Tyr Gln Gln
Lys Pro 165 170 175ggc cag gcc cct gtc ctg gtc gtc tat gat gat agc
gac cgg ccc tca 576Gly Gln Ala Pro Val Leu Val Val Tyr Asp Asp Ser
Asp Arg Pro Ser 180 185 190ggg atc cct gag cga ttc tct ggc tcc aac
tct ggg gac acg gcc acc 624Gly Ile Pro Glu Arg Phe Ser Gly Ser Asn
Ser Gly Asp Thr Ala Thr 195 200 205ctg acc atc agc agg gtc gag gcc
ggg gat gag gcc gat tat tac tgt 672Leu Thr Ile Ser Arg Val Glu Ala
Gly Asp Glu Ala Asp Tyr Tyr Cys 210 215 220cag gtg tgg gat gac agt
agt gat ctg gtg gta ttc ggc gga ggg acc 720Gln Val Trp Asp Asp Ser
Ser Asp Leu Val Val Phe Gly Gly Gly Thr225 230 235 240aag gtc acc
gtc cta ggt gcg gcc gca 747Lys Val Thr Val Leu Gly Ala Ala Ala
245176249PRTArtificial sequenceSynthetic Construct 176Ala Met Ala
Gln Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly
Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Gly
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ala Thr Ile Phe Tyr Asp Gly Ser Tyr Lys Asp Tyr Ala
50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly Ser Lys Val Gly Asp Phe
Asp Tyr Trp Gly 100 105 110Gln Gly Thr Leu Val Thr Val Ser Ser Gly
Thr Gly Gly Ser Gly Gly 115 120 125Thr Gly Ser Gly Thr Gly Gly Ser
Thr Gln Pro Val Leu Thr Gln Pro 130 135 140Pro Ser Val Ser Val Ala
Pro Gly Gln Thr Ala Arg Ile Ser Cys Gly145 150 155 160Gly Asp Asn
Ile Gly Thr Asn Thr Val Gln Trp Tyr Gln Gln Lys Pro 165 170 175Gly
Gln Ala Pro Val Leu Val Val Tyr Asp Asp Ser Asp Arg Pro Ser 180 185
190Gly Ile Pro Glu Arg Phe Ser Gly Ser Asn Ser Gly Asp Thr Ala Thr
195 200 205Leu Thr Ile Ser Arg Val Glu Ala Gly Asp Glu Ala Asp Tyr
Tyr Cys 210 215 220Gln Val Trp Asp Asp Ser Ser Asp Leu Val Val Phe
Gly Gly Gly Thr225 230 235 240Lys Val Thr Val Leu Gly Ala Ala Ala
245177774DNAArtificial sequenceSC04-060 177gcc atg gcc cag gtg cag
ctg gtg gag tct ggc cca gga ctg gtg aag 48Ala Met Ala Gln Val Gln
Leu Val Glu Ser Gly Pro Gly Leu Val Lys1 5 10 15gct tcg gag acc ctg
tcc ctc act tgc acg gtc tct gat ggc tcc atc 96Ala Ser Glu Thr Leu
Ser Leu Thr Cys Thr Val Ser Asp Gly Ser Ile 20 25 30agt agt ttc tac
tgg agc tgg atc cgg cag ccc ccc ggg aag gga ctg 144Ser Ser Phe Tyr
Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 35 40 45gag tgg gtt
ggg gaa atc cag gac act ggg agg acc aat tac aac ccc 192Glu Trp Val
Gly Glu Ile Gln Asp Thr Gly Arg Thr Asn Tyr Asn Pro 50 55 60tcc ctc
aag agt cga gtc act ata tca cta gac acg tcc aag aac cag 240Ser Leu
Lys Ser Arg Val Thr Ile Ser Leu Asp Thr Ser Lys Asn Gln65 70 75
80ttc tcc ctg acg ttg agc tct gtg acc gct gcg gac acg gcc gtg tat
288Phe Ser Leu Thr Leu Ser Ser Val Thr Ala Ala Asp Thr Ala Val Tyr
85 90 95tac tgc gcg aga gag aag gag aaa tac tct gat aga agc ggt tat
tcg 336Tyr Cys Ala Arg Glu Lys Glu Lys Tyr Ser Asp Arg Ser Gly Tyr
Ser 100 105 110tac tac tac tat tac atg gac gtc tgg ggc aaa ggg acc
acg gtc acc 384Tyr Tyr Tyr Tyr Tyr Met Asp Val Trp Gly Lys Gly Thr
Thr Val Thr 115 120 125gtc tcg agc ggt acg ggc ggt tca ggc gga acc
ggc agc ggc act ggc 432Val Ser Ser Gly Thr Gly Gly Ser Gly Gly Thr
Gly Ser Gly Thr Gly 130 135 140ggg tcg acg gac atc cag atg acc cag
tct cca tcc tcc ctg tct gca 480Gly Ser Thr Asp Ile Gln Met Thr Gln
Ser Pro Ser Ser Leu Ser Ala145 150 155 160tct gta gga gac aga gtc
acc atc act tgc cgg gca agt cag ggc att 528Ser Val Gly Asp Arg Val
Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile 165 170 175agc acc tat tta
aat tgg tat cag cag aaa cca ggg aaa gcc cct aac 576Ser Thr Tyr Leu
Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Asn 180 185 190ctc ctg
atc tac ggt gca tct aat ttg caa agt ggg gtc cca tca agg 624Leu Leu
Ile Tyr Gly Ala Ser Asn Leu Gln Ser Gly Val Pro Ser Arg 195 200
205ttc agt ggc agt gaa tct ggg aca gat ttc act ctc acc atc agc agt
672Phe Ser Gly Ser Glu Ser Gly Thr Asp Phe Thr Leu Thr Ile Ser Ser
210 215 220cta caa cct gaa gat ttt gca act tac tac tgt cag cag agt
ttc act 720Leu Gln Pro Glu Asp Phe Ala Thr Tyr Tyr Cys Gln Gln Ser
Phe Thr225 230 235 240acc cct cgc acg ttc ggc caa ggg acc aag ctg
gag atc aaa cgt gcg 768Thr Pro Arg Thr Phe Gly Gln Gly Thr Lys Leu
Glu Ile Lys Arg Ala 245 250 255gcc gca 774Ala
Ala178258PRTArtificial sequenceSynthetic Construct 178Ala Met Ala
Gln Val Gln Leu Val Glu Ser Gly Pro Gly Leu Val Lys1 5 10 15Ala Ser
Glu Thr Leu Ser Leu Thr Cys Thr Val Ser Asp Gly Ser Ile 20 25 30Ser
Ser Phe Tyr Trp Ser Trp Ile Arg Gln Pro Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Gly Glu Ile Gln Asp Thr Gly Arg Thr Asn Tyr Asn Pro
50 55 60Ser Leu Lys Ser Arg Val Thr Ile Ser Leu Asp Thr Ser Lys Asn
Gln65 70 75 80Phe Ser Leu Thr Leu Ser Ser Val Thr Ala Ala Asp Thr
Ala Val Tyr 85 90 95Tyr Cys Ala Arg Glu Lys Glu Lys Tyr Ser Asp Arg
Ser Gly Tyr Ser 100 105 110Tyr Tyr Tyr Tyr Tyr Met Asp Val Trp Gly
Lys Gly Thr Thr Val Thr 115 120 125Val Ser Ser Gly Thr Gly Gly Ser
Gly Gly Thr Gly Ser Gly Thr Gly 130 135 140Gly Ser Thr Asp Ile Gln
Met Thr Gln Ser Pro Ser Ser Leu Ser Ala145 150 155 160Ser Val Gly
Asp Arg Val Thr Ile Thr Cys Arg Ala Ser Gln Gly Ile 165 170 175Ser
Thr Tyr Leu Asn Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro Asn 180 185
190Leu Leu Ile Tyr Gly Ala Ser Asn Leu Gln Ser Gly Val Pro Ser Arg
195 200 205Phe Ser Gly Ser Glu Ser Gly Thr Asp Phe Thr Leu Thr Ile
Ser Ser 210 215 220Leu Gln Pro Glu Asp Phe Ala Thr Tyr Tyr Cys Gln
Gln Ser Phe Thr225 230 235 240Thr Pro Arg Thr Phe Gly Gln Gly Thr
Lys Leu Glu Ile Lys Arg Ala 245 250 255Ala Ala179759DNAArtificial
sequenceSC04-073 179gcc atg gcc cag gtg cag ctg gtg cag tct ggg gga
ggc gtg gcc cag 48Ala Met Ala Gln Val Gln Leu Val Gln Ser Gly Gly
Gly Val Ala Gln1 5 10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcg
tct gga ttc acc ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala
Ser Gly Phe Thr Phe 20 25 30agt agt tat ggc atg cac tgg gtc cgc cag
gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln
Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg gca gat ata tca tat gat
gga agt aat aaa tac tat gca 192Glu Trp Val Ala Asp Ile Ser Tyr Asp
Gly Ser Asn Lys Tyr Tyr Ala 50 55 60gac tcc gtg aag ggc cga ttc acc
att tcc aga gac aat tcc aag aac 240Asp Ser Val Lys Gly Arg Phe Thr
Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80acg ctg tat ctg caa atg
aac agc ctg aga gct gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met
Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa
gat ggg ctg gat tta act gga acg att cag cca 336Tyr Tyr Cys Ala Lys
Asp Gly Leu Asp Leu Thr Gly Thr Ile Gln Pro 100 105 110ttt ggc tac
tgg ggc cag ggc acc ctg gtc acc gtc tcg agc ggt acg 384Phe Gly Tyr
Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr 115 120 125ggc
ggt tca ggc gga acc ggc agc ggc act ggc ggg tcg acg gac atc 432Gly
Gly Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile 130 135
140cag ttg acc cag tcg cca tcc ttc ctg tct gca tct gta gga gac aga
480Gln Leu Thr Gln Ser Pro Ser Phe Leu Ser Ala Ser Val Gly Asp
Arg145 150 155 160gtc acc atc act tgc cgg gcc agt cac agt att agt
agc tgg ttg gcc 528Val Thr Ile Thr Cys Arg Ala Ser His Ser Ile Ser
Ser Trp Leu Ala 165 170 175tgg tat cag cag aaa cca ggg aaa gcc cct
aag ctc ctg atc tat aag 576Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile Tyr Lys 180 185 190gca tct agt tta gaa agt ggg gtc
cca tca agg ttc agc ggc agt gga 624Ala Ser Ser Leu Glu Ser Gly Val
Pro Ser Arg Phe Ser Gly Ser Gly 195 200 205tct ggg aca gat ttc act
ctc acc atc agc agc ctg cag cct gaa gat 672Ser Gly Thr Asp Phe Thr
Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp 210 215 220ttt gca act tat
tac tgt cta caa gat tac aat tac cct cgg acg ttc 720Phe Ala Thr Tyr
Tyr Cys Leu Gln Asp Tyr Asn Tyr Pro Arg Thr Phe225 230 235 240ggc
caa ggg acc aag ctg gag atc aaa cgt gcg gcc gca 759Gly Gln Gly Thr
Lys Leu Glu Ile Lys Arg Ala Ala Ala 245 250180253PRTArtificial
sequenceSynthetic Construct 180Ala Met Ala Gln Val Gln Leu Val Gln
Ser Gly Gly Gly Val Ala Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Asp Ile
Ser Tyr Asp Gly Ser Asn Lys Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Asp Gly Leu Asp Leu Thr Gly Thr Ile Gln Pro 100 105
110Phe Gly Tyr Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr
115 120 125Gly Gly Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr
Asp Ile 130 135 140Gln Leu Thr Gln Ser Pro Ser Phe Leu Ser Ala Ser
Val Gly Asp Arg145 150 155 160Val Thr Ile Thr Cys Arg Ala Ser His
Ser Ile Ser Ser Trp Leu Ala 165 170 175Trp Tyr Gln Gln Lys Pro Gly
Lys Ala Pro Lys Leu Leu Ile Tyr Lys 180 185 190Ala Ser Ser Leu Glu
Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly 195 200 205Ser Gly Thr
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp 210 215 220Phe
Ala Thr Tyr Tyr Cys Leu Gln Asp Tyr Asn Tyr Pro Arg Thr Phe225 230
235 240Gly Gln Gly Thr Lys Leu Glu Ile Lys Arg Ala Ala Ala 245
250181753DNAArtificial sequenceSC04-097 181gcc atg gcc gaa gtg cag
ctg gtg cag tct ggg gga cac ttg gta cag 48Ala Met Ala Glu Val Gln
Leu Val Gln Ser Gly Gly His Leu Val Gln1 5 10 15cct ggg ggg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttt 96Pro Gly Gly Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agc agc tat gcc
atg agc tgg gtc cgc cag gct cca ggg aag ggg ctg 144Ser Ser Tyr Ala
Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtc
tca ctt att att ggt agc ggt cgt agc aca tac tac gca 192Glu Trp Val
Ser Leu Ile Ile Gly Ser Gly Arg Ser Thr Tyr Tyr Ala 50 55 60gac tcc
gtg aag ggc cgg ttc acc atc tcc aga gac aat tcc aag aac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gcc gag gac acg gcc gta
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa acc gcg agt aat ctt gga agg ggg ggt atg
gac 336Tyr Tyr Cys Ala Lys Thr Ala Ser Asn Leu Gly Arg Gly Gly Met
Asp 100 105 110gtc tgg ggc caa ggg acc acg gtc acc gtc tcg agc ggt
acg ggc ggt 384Val Trp Gly Gln Gly Thr Thr Val Thr Val Ser Ser Gly
Thr Gly Gly 115 120 125tca ggc gga acc ggc agc ggc act ggc ggg tcg
acg gac att cag ttg 432Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser
Thr Asp Ile Gln Leu 130 135 140acc cag tct cca tcc tcc ctg tct gca
tct gtg gga gac aga gtc act 480Thr Gln Ser Pro Ser Ser Leu Ser Ala
Ser Val Gly Asp Arg Val Thr145 150 155 160atc act tgc cgg gcc agt
cag ggc att agc agt cat tta gcc tgg tat 528Ile Thr Cys Arg Ala Ser
Gln Gly Ile Ser Ser His Leu Ala Trp Tyr 165 170 175cag caa aaa cca
ggg aaa gcc cct aag ctc ctg atc tat gct gca tcc 576Gln Gln Lys Pro
Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser 180 185 190agt ttg
caa agt ggg gtc cca tca agg ttc agc ggc agt gga tct ggg 624Ser Leu
Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly 195 200
205aca gaa ttc act ctc acc atc agc agc ctg cag cct gaa gat ttt gca
672Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala
210 215 220act tat tac tgt caa cag ttt aat agt tac ccg atc acc ttc
ggc caa 720Thr Tyr Tyr Cys Gln Gln Phe Asn Ser Tyr Pro Ile Thr Phe
Gly Gln225 230 235 240ggg aca cga ctg gag att aaa cgt gcg gcc gca
753Gly Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala 245
250182251PRTArtificial sequenceSynthetic Construct 182Ala Met Ala
Glu Val Gln Leu Val Gln Ser Gly Gly His Leu Val Gln1 5 10 15Pro Gly
Gly Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser
Ser Tyr Ala Met Ser Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ser Leu Ile Ile Gly Ser Gly Arg Ser Thr Tyr Tyr Ala
50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Thr Ala Ser Asn Leu Gly Arg
Gly Gly Met Asp 100 105 110Val Trp Gly Gln Gly Thr Thr Val Thr Val
Ser Ser Gly Thr Gly Gly 115 120 125Ser Gly Gly Thr Gly Ser Gly Thr
Gly Gly Ser Thr Asp Ile Gln Leu 130 135 140Thr Gln Ser Pro Ser Ser
Leu Ser Ala Ser Val Gly Asp Arg Val Thr145 150 155 160Ile Thr Cys
Arg Ala Ser Gln Gly Ile Ser Ser His Leu Ala Trp Tyr 165 170 175Gln
Gln Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser 180 185
190Ser Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly
195 200 205Thr Glu Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp
Phe Ala 210 215 220Thr Tyr Tyr Cys Gln Gln Phe Asn Ser Tyr Pro Ile
Thr Phe Gly Gln225 230 235 240Gly Thr Arg Leu Glu Ile Lys Arg Ala
Ala Ala 245 250183747DNAArtificial sequenceSC04-098 183gcc atg gcc
gaa gtg cag ctg gtg cag tct ggg gga ggc gcg gtc cag 48Ala Met Ala
Glu Val Gln Leu Val Gln Ser Gly Gly Gly Ala Val Gln1 5
10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc
ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe 20 25 30agt agc tat ggc atg cac tgg gtc cgc cag gct cca ggc aag
ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu 35 40 45gag tgg gtg gct gtt ata tta tat gat gga agt gat aaa
ttc tat gca 192Glu Trp Val Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys
Phe Tyr Ala 50 55 60gac tcc gtg aag ggc cga ttc acc atc tcc aga gac
aat tcc aag aac 240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn65 70 75 80acg ctg tat ctg cag atg aac agc ctg aga
gct gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa gta gca gtg gct
ggt acg cac ttt gac tac tgg 336Tyr Tyr Cys Ala Lys Val Ala Val Ala
Gly Thr His Phe Asp Tyr Trp 100 105 110ggc cag gga acc ctg gtc acc
gtc tcg agc ggt acg ggc ggt tca ggc 384Gly Gln Gly Thr Leu Val Thr
Val Ser Ser Gly Thr Gly Gly Ser Gly 115 120 125gga acc ggc agc ggc
act ggc ggg tcg acg gac atc cag atg acc cag 432Gly Thr Gly Ser Gly
Thr Gly Gly Ser Thr Asp Ile Gln Met Thr Gln 130 135 140tct cca tcc
tcc ctg tct gca tct gta gga gac aga gtc acc atc act 480Ser Pro Ser
Ser Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155
160tgc cgg gca agt cag ggc att aga aat gat tta ggc tgg tat cag cag
528Cys Arg Ala Ser Gln Gly Ile Arg Asn Asp Leu Gly Trp Tyr Gln Gln
165 170 175aaa cca ggg aaa gcc cct aag ctc ctg atc tat gct gca tcc
agt ttg 576Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser
Ser Leu 180 185 190caa agt ggg gtc cca tca agg ttc agc ggc agt gga
tct ggg aca gat 624Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly
Ser Gly Thr Asp 195 200 205ttc act ctc acc atc agc agc ctg cag cct
gaa gat ttt gca act tat 672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro
Glu Asp Phe Ala Thr Tyr 210 215 220tac tgt caa cag ctt aat agt tac
cct ccc act ttc ggc gga ggg acc 720Tyr Cys Gln Gln Leu Asn Ser Tyr
Pro Pro Thr Phe Gly Gly Gly Thr225 230 235 240aag gtg gaa atc aaa
cgt gcg gcc gca 747Lys Val Glu Ile Lys Arg Ala Ala Ala
245184249PRTArtificial sequenceSynthetic Construct 184Ala Met Ala
Glu Val Gln Leu Val Gln Ser Gly Gly Gly Ala Val Gln1 5 10 15Pro Gly
Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe Tyr Ala
50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Val Ala Val Ala Gly Thr His
Phe Asp Tyr Trp 100 105 110Gly Gln Gly Thr Leu Val Thr Val Ser Ser
Gly Thr Gly Gly Ser Gly 115 120 125Gly Thr Gly Ser Gly Thr Gly Gly
Ser Thr Asp Ile Gln Met Thr Gln 130 135 140Ser Pro Ser Ser Leu Ser
Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160Cys Arg Ala
Ser Gln Gly Ile Arg Asn Asp Leu Gly Trp Tyr Gln Gln 165 170 175Lys
Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185
190Gln Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp
195 200 205Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala
Thr Tyr 210 215 220Tyr Cys Gln Gln Leu Asn Ser Tyr Pro Pro Thr Phe
Gly Gly Gly Thr225 230 235 240Lys Val Glu Ile Lys Arg Ala Ala Ala
245185747DNAArtificial sequenceSC04-103 185gcc atg gcc cag gtg cag
ctg cag gag tcg ggg gga ggc gtg gtc cag 48Ala Met Ala Gln Val Gln
Leu Gln Glu Ser Gly Gly Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc
atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly
Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg
gca gtt ata tta tat gat gga agt gat aaa tac tat gca 192Glu Trp Val
Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Tyr Tyr Ala 50 55 60gac tcc
gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac acg gct gtg
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa gtc gct gtg gct ggg gaa agc ttt gac tcc
tgg 336Tyr Tyr Cys Ala Lys Val Ala Val Ala Gly Glu Ser Phe Asp Ser
Trp 100 105 110ggc cgg ggc acc ctg gtc acc gtc tcg agc ggt acg ggc
ggt tca ggc 384Gly Arg Gly Thr Leu Val Thr Val Ser Ser Gly Thr Gly
Gly Ser Gly 115 120 125gga acc ggc agc ggc act ggc ggg tcg acg gac
atc cag ttg acc cag 432Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp
Ile Gln Leu Thr Gln 130 135 140tct cca tct tcc gtg tct gca tct gta
gga gac aga gtc acc atc act 480Ser Pro Ser Ser Val Ser Ala Ser Val
Gly Asp Arg Val Thr Ile Thr145 150 155 160tgt cgg gcg agt cag ggt
att agc agc tgg tta gcc tgg tat cag cag 528Cys Arg Ala Ser Gln Gly
Ile Ser Ser Trp Leu Ala Trp Tyr Gln Gln 165 170 175aag cca ggg aaa
gcc cct agg tcc ctg atc tat gat gca tcc agt ttg 576Lys Pro Gly Lys
Ala Pro Arg Ser Leu Ile Tyr Asp Ala Ser Ser Leu 180 185 190caa agt
ggg gtc cca tca agg ttc agc ggc agt gga tct ggg aca gac 624Gln Ser
Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200
205ttt act ctc acc atc agc agc ctg cag cct gaa gat ttt gca act tac
672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr
210 215 220tat tgt caa cag gct gac agt ttc ccg atc acc ttc ggc caa
ggg aca 720Tyr Cys Gln Gln Ala Asp Ser Phe Pro Ile Thr Phe Gly Gln
Gly Thr225 230 235 240cga ctg gag att aaa cgt gcg gcc gca 747Arg
Leu Glu Ile Lys Arg Ala Ala Ala 245186249PRTArtificial
sequenceSynthetic Construct 186Ala Met Ala Gln Val Gln Leu Gln Glu
Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Val Ile
Leu Tyr Asp Gly Ser Asp Lys Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Val Ala Val Ala Gly Glu Ser Phe Asp Ser Trp 100 105
110Gly Arg Gly Thr Leu Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly
115 120 125Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu
Thr Gln 130 135 140Ser Pro Ser Ser Val Ser Ala Ser Val Gly Asp Arg
Val Thr Ile Thr145 150 155 160Cys Arg Ala Ser Gln Gly Ile Ser Ser
Trp Leu Ala Trp Tyr Gln Gln 165 170 175Lys Pro Gly Lys Ala Pro Arg
Ser Leu Ile Tyr Asp Ala Ser Ser Leu 180 185 190Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200 205Phe Thr Leu
Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr 210 215 220Tyr
Cys Gln Gln Ala Asp Ser Phe Pro Ile Thr Phe Gly Gln Gly Thr225 230
235 240Arg Leu Glu Ile Lys Arg Ala Ala Ala 245187759DNAArtificial
sequenceSC04-104 187gcc atg gcc cag gtg cag ctg cag gag tcg ggg gga
ggc gtg gtc cag 48Ala Met Ala Gln Val Gln Leu Gln Glu Ser Gly Gly
Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcc
tct gga ttc acc ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala
Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc atg cac tgg gtc cgc cag
gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln
Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg gca act ata tca tat gat
gga aat gtt aaa gac tat gca 192Glu Trp Val Ala Thr Ile Ser Tyr Asp
Gly Asn Val Lys Asp Tyr Ala 50 55 60gac tcc gtg aag ggc cga ttc acc
atc tcc aga gac aat tcc aag aac 240Asp Ser Val Lys Gly Arg Phe Thr
Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80acg ctg tat ctg caa atg
aac agc ctg aga act gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met
Asn Ser Leu Arg Thr Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa
ata gtg gtg gtg acc gcc ctc gat gct ttt gat 336Tyr Tyr Cys Ala Lys
Ile Val Val Val Thr Ala Leu Asp Ala Phe Asp 100 105 110atc tgg ggc
caa ggg aca atg gtc acc gtc tcg agc ggt acg ggc ggt 384Ile Trp Gly
Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly 115 120 125tca
ggc gga acc ggc agc ggc act ggc ggg tcg acg gac atc cag ttg 432Ser
Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu 130 135
140acc cag tct cct tcc acc ctg tct gca tct gta gga gac aga gtc acc
480Thr Gln Ser Pro Ser Thr Leu Ser Ala Ser Val Gly Asp Arg Val
Thr145 150 155 160atc act tgc cgg gcc agt cag att ctt ggt cac tgg
ttg ccc ttg tcc 528Ile Thr Cys Arg Ala Ser Gln Ile Leu Gly His Trp
Leu Pro Leu Ser 165 170 175tgg tat cag cag aaa cca ggt aaa gcc cct
aaa ctc ctg atc tct aag 576Trp Tyr Gln Gln Lys Pro Gly Lys Ala Pro
Lys Leu Leu Ile Ser Lys 180 185 190gcg tct agt tta gaa agt gga gtc
cca cca agg ttc agc ggc agt gga 624Ala Ser Ser Leu Glu Ser Gly Val
Pro Pro Arg Phe Ser Gly Ser Gly 195 200 205tct ggg tca gat ttc act
ctc acc atc agc agc ctg cag ccc gat gat 672Ser Gly Ser Asp Phe Thr
Leu Thr Ile Ser Ser Leu Gln Pro Asp Asp 210 215 220ttt gca act tat
tac tgc ctc caa tat cat gag tac ccg ctc acc ttc 720Phe Ala Thr Tyr
Tyr Cys Leu Gln Tyr His Glu Tyr Pro Leu Thr Phe225 230 235 240ggc
gga ggg acc aag ctg gag atc aaa cgt gcg gcc gca 759Gly Gly Gly Thr
Lys Leu Glu Ile Lys Arg Ala Ala Ala 245 250188253PRTArtificial
sequenceSynthetic Construct 188Ala Met Ala Gln Val Gln Leu Gln Glu
Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Thr Ile
Ser Tyr Asp Gly Asn Val Lys Asp Tyr Ala 50 55 60Asp Ser Val Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Thr Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Ile Val Val Val Thr Ala Leu Asp Ala Phe Asp 100 105
110Ile Trp Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly
115 120 125Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile
Gln Leu 130 135 140Thr Gln Ser Pro Ser Thr Leu Ser Ala Ser Val Gly
Asp Arg Val Thr145 150 155 160Ile Thr Cys Arg Ala Ser Gln Ile Leu
Gly His Trp Leu Pro Leu Ser 165 170 175Trp Tyr Gln Gln Lys Pro Gly
Lys Ala Pro Lys Leu Leu Ile Ser Lys 180 185 190Ala Ser Ser Leu Glu
Ser Gly Val Pro Pro Arg Phe Ser Gly Ser Gly 195 200 205Ser Gly Ser
Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Asp Asp 210 215 220Phe
Ala Thr Tyr Tyr Cys Leu Gln Tyr His Glu Tyr Pro Leu Thr Phe225 230
235 240Gly Gly Gly Thr Lys Leu Glu Ile Lys Arg Ala Ala Ala 245
250189750DNAArtificial sequenceSC04-108 189gcc atg gcc gaa gtg cag
ctg gtg cag tct ggg gga ggc ttg gta cag 48Ala Met Ala Glu Val Gln
Leu Val Gln Ser Gly Gly Gly Leu Val Gln1 5 10 15cct ggg ggg tcc ctg
aga ctc tcc tgt gca gcg tct gga ttc acc ttc 96Pro Gly Gly Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc
atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly
Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg
gca gtt ata tta tat gat gga agt gat aag ttc tat gca 192Glu Trp Val
Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe Tyr Ala 50 55 60gac tcc
gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag gac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asp65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac acg gct gtg
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa ttt atg ata gta gca gat gat gct ttt gat
atc 336Tyr Tyr Cys Ala Lys Phe Met Ile Val Ala Asp Asp Ala Phe Asp
Ile 100 105 110tgg ggc caa ggg aca atg gtc acc gtc tcg agc ggt acg
ggc ggt tca 384Trp Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr
Gly Gly Ser 115 120 125ggc gga acc ggc agc ggc act ggc ggg tcg acg
gac atc cag ttg acc 432Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr
Asp Ile Gln Leu Thr 130 135 140cag tct cca tcc tca ctg tct gca tct
gta gga gac aga gtc acc atc 480Gln Ser Pro Ser Ser Leu Ser Ala Ser
Val Gly Asp Arg Val Thr Ile145 150 155 160act tgt cgg gcg agt cag
ggc att agc agt cat tta gtc tgg tat cag 528Thr Cys Arg Ala Ser Gln
Gly Ile Ser Ser His Leu Val Trp Tyr Gln 165 170 175cag aaa cca ggg
aaa gcc cct aag tcc ctg atc tat gct gca tcc agt 576Gln Lys Pro Gly
Lys Ala Pro Lys Ser Leu Ile Tyr Ala Ala Ser Ser 180 185 190ttg caa
agt ggg gtc cca tca agg ttc agc ggc agt gaa tct gcg aca 624Leu Gln
Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Glu Ser Ala Thr 195 200
205gat ttc act ctc acc atc agc agc ctg cag cct gaa gat ttt gca act
672Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr
210 215 220tat tac tgc caa cag tat tac agt tac cct atc acc ttc ggc
caa ggg 720Tyr Tyr Cys Gln Gln Tyr Tyr Ser Tyr Pro Ile Thr Phe Gly
Gln Gly225 230 235 240aca cga ctg gag att aaa cgt gcg gcc gca
750Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala 245
250190250PRTArtificial sequenceSynthetic Construct 190Ala Met Ala
Glu Val Gln Leu Val Gln Ser Gly Gly Gly Leu Val Gln1 5 10 15Pro Gly
Gly Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe Tyr Ala
50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asp65 70 75 80Thr Leu Tyr Leu
Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr Cys
Ala Lys Phe Met Ile Val Ala Asp Asp Ala Phe Asp Ile 100 105 110Trp
Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser 115 120
125Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu Thr
130 135 140Gln Ser Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val
Thr Ile145 150 155 160Thr Cys Arg Ala Ser Gln Gly Ile Ser Ser His
Leu Val Trp Tyr Gln 165 170 175Gln Lys Pro Gly Lys Ala Pro Lys Ser
Leu Ile Tyr Ala Ala Ser Ser 180 185 190Leu Gln Ser Gly Val Pro Ser
Arg Phe Ser Gly Ser Glu Ser Ala Thr 195 200 205Asp Phe Thr Leu Thr
Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr 210 215 220Tyr Tyr Cys
Gln Gln Tyr Tyr Ser Tyr Pro Ile Thr Phe Gly Gln Gly225 230 235
240Thr Arg Leu Glu Ile Lys Arg Ala Ala Ala 245
250191744DNAArtificial sequenceSC04-120 191gcc atg gcc gag gtg cag
ctg gtg cag tct ggg gga ggc ttg gta cag 48Ala Met Ala Glu Val Gln
Leu Val Gln Ser Gly Gly Gly Leu Val Gln1 5 10 15cct ggc agg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt acc tat ggc
atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser Thr Tyr Gly
Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg
gca act ata tca tat gat gga agt att aaa gac tat gca 192Glu Trp Val
Ala Thr Ile Ser Tyr Asp Gly Ser Ile Lys Asp Tyr Ala 50 55 60gac tcc
gag aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac 240Asp Ser
Glu Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac acg gct gtg
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa ggg ggg aag act gga gag ttt gac tac tgg
ggc 336Tyr Tyr Cys Ala Lys Gly Gly Lys Thr Gly Glu Phe Asp Tyr Trp
Gly 100 105 110cag gga acc ctg gtc acc gtc tcg agc ggt acg ggc ggt
tca ggc gga 384Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr Gly Gly
Ser Gly Gly 115 120 125acc ggc agc ggc act ggc ggg tcg acg gac atc
cag ttg acc cag tct 432Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile
Gln Leu Thr Gln Ser 130 135 140cct tcc acc ctg tct gca tct gta gga
gac aga gtc acc atc act tgc 480Pro Ser Thr Leu Ser Ala Ser Val Gly
Asp Arg Val Thr Ile Thr Cys145 150 155 160cgg gcc agt cag ggc att
aac agt tat tta gcc tgg tat cag caa gaa 528Arg Ala Ser Gln Gly Ile
Asn Ser Tyr Leu Ala Trp Tyr Gln Gln Glu 165 170 175cca ggg aaa gcc
cct aaa ctc ctg atc tat gct gca tcc act ttg caa 576Pro Gly Lys Ala
Pro Lys Leu Leu Ile Tyr Ala Ala Ser Thr Leu Gln 180 185 190agt ggg
gtc cca tca agg ttc agc ggc agt gga tct ggg aca gaa ttc 624Ser Gly
Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Glu Phe 195 200
205act ctc aca atc agc agc ctg cag cct gaa gat ttt gca act tat tac
672Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr Tyr
210 215 220tgt caa cag ctt aat agt tac ccc ttc act ttc ggc cct ggg
acc aaa 720Cys Gln Gln Leu Asn Ser Tyr Pro Phe Thr Phe Gly Pro Gly
Thr Lys225 230 235 240gtg gat atc aaa cgt gcg gcc gca 744Val Asp
Ile Lys Arg Ala Ala Ala 245192248PRTArtificial sequenceSynthetic
Construct 192Ala Met Ala Glu Val Gln Leu Val Gln Ser Gly Gly Gly
Leu Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser
Gly Phe Thr Phe 20 25 30Ser Thr Tyr Gly Met His Trp Val Arg Gln Ala
Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Thr Ile Ser Tyr Asp Gly
Ser Ile Lys Asp Tyr Ala 50 55 60Asp Ser Glu Lys Gly Arg Phe Thr Ile
Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn
Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly
Gly Lys Thr Gly Glu Phe Asp Tyr Trp Gly 100 105 110Gln Gly Thr Leu
Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly Gly 115 120 125Thr Gly
Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu Thr Gln Ser 130 135
140Pro Ser Thr Leu Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr
Cys145 150 155 160Arg Ala Ser Gln Gly Ile Asn Ser Tyr Leu Ala Trp
Tyr Gln Gln Glu 165 170 175Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr
Ala Ala Ser Thr Leu Gln 180 185 190Ser Gly Val Pro Ser Arg Phe Ser
Gly Ser Gly Ser Gly Thr Glu Phe 195 200 205Thr Leu Thr Ile Ser Ser
Leu Gln Pro Glu Asp Phe Ala Thr Tyr Tyr 210 215 220Cys Gln Gln Leu
Asn Ser Tyr Pro Phe Thr Phe Gly Pro Gly Thr Lys225 230 235 240Val
Asp Ile Lys Arg Ala Ala Ala 245193747DNAArtificial sequenceSC04-125
193gcc atg gcc cag gtg cag ctg gtg gag tct ggg gga ggc gtg gtc cag
48Ala Met Ala Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln1
5 10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc
ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr
Phe 20 25 30agt agc tat ggc atg cac tgg gtc cgc cag gct cca ggc aag
ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys
Gly Leu 35 40 45gag tgg gtg gca gtt ata tca tat gat gga agt gat aaa
tac tat gca 192Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys
Tyr Tyr Ala 50 55 60gac tcc gtg aag ggc cga ttc acc atc tcc aga gac
aat tcc aag aac 240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp
Asn Ser Lys Asn65 70 75 80acg ctc tat ctg caa atg aac agc ttg aga
gct gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg
Ala Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aag ata gca aca gct
ggt acc ggg ttt gac tac tgg 336Tyr Tyr Cys Ala Lys Ile Ala Thr Ala
Gly Thr Gly Phe Asp Tyr Trp 100 105 110ggc cag gga acc ctg gtc acc
gtc tcg agc ggt acg ggc ggt tca ggc 384Gly Gln Gly Thr Leu Val Thr
Val Ser Ser Gly Thr Gly Gly Ser Gly 115 120 125gga acc ggc agc ggc
act ggc ggg tcg acg gac atc cag atg acc cag 432Gly Thr Gly Ser Gly
Thr Gly Gly Ser Thr Asp Ile Gln Met Thr Gln 130 135 140tct cca tct
tcc gtg tct gca tct gta gga gac aga gtc acc atc act 480Ser Pro Ser
Ser Val Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155
160tgt cgg gcg agt cag ggc att agc agt tat tta gcc tgg tat cag caa
528Cys Arg Ala Ser Gln Gly Ile Ser Ser Tyr Leu Ala Trp Tyr Gln Gln
165 170 175aaa cca ggg aaa gcc cct aag ctc ctg atc tat gat gcc tcc
agt ttg 576Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser
Ser Leu 180 185 190gaa agt ggg gtc cca tca agg ttc agc ggc agt gga
tct ggg aca gaa 624Glu Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly
Ser Gly Thr Glu 195 200 205ttc act ctc acc atc agc agc ctg cag cct
gat gat ttt gca act tat 672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro
Asp Asp Phe Ala Thr Tyr 210 215 220tac tgt caa caa ctt aac agt tac
cca ctc act ttc ggc gga ggg acc 720Tyr Cys Gln Gln Leu Asn Ser Tyr
Pro Leu Thr Phe Gly Gly Gly Thr225 230 235 240aag gtg gag atc aaa
cgt gcg gcc gca 747Lys Val Glu Ile Lys Arg Ala Ala Ala
245194249PRTArtificial sequenceSynthetic Construct 194Ala Met Ala
Gln Val Gln Leu Val Glu Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly
Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ala Val Ile Ser Tyr Asp Gly Ser Asp Lys Tyr Tyr Ala
50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Ile Ala Thr Ala Gly Thr Gly
Phe Asp Tyr Trp 100 105 110Gly Gln Gly Thr Leu Val Thr Val Ser Ser
Gly Thr Gly Gly Ser Gly 115 120 125Gly Thr Gly Ser Gly Thr Gly Gly
Ser Thr Asp Ile Gln Met Thr Gln 130 135 140Ser Pro Ser Ser Val Ser
Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160Cys Arg Ala
Ser Gln Gly Ile Ser Ser Tyr Leu Ala Trp Tyr Gln Gln 165 170 175Lys
Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Ser Leu 180 185
190Glu Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Glu
195 200 205Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Asp Asp Phe Ala
Thr Tyr 210 215 220Tyr Cys Gln Gln Leu Asn Ser Tyr Pro Leu Thr Phe
Gly Gly Gly Thr225 230 235 240Lys Val Glu Ile Lys Arg Ala Ala Ala
245195756DNAArtificial sequenceSC04-126 195gcc atg gcc cag gtc acc
ttg aag gag tct ggt ccc acg ctg gtg aac 48Ala Met Ala Gln Val Thr
Leu Lys Glu Ser Gly Pro Thr Leu Val Asn1 5 10 15ccc aca cag acc ctc
acg ttg acc tgc acc ttc tct ggg ttc tcg ctc 96Pro Thr Gln Thr Leu
Thr Leu Thr Cys Thr Phe Ser Gly Phe Ser Leu 20 25 30agc act ggt gga
gtg ggt gtg ggc tgg ttc cgt cag ccc cca ggg aag 144Ser Thr Gly Gly
Val Gly Val Gly Trp Phe Arg Gln Pro Pro Gly Lys 35 40 45gcc ctg gag
tgg ctt gca cgc att gat tgg gat gat gat aaa tac tac 192Ala Leu Glu
Trp Leu Ala Arg Ile Asp Trp Asp Asp Asp Lys Tyr Tyr 50 55 60agc aca
tct ctg aag acc agg ctc acc atc tcc aag gac acc tcc aaa 240Ser Thr
Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Asp Thr Ser Lys65 70 75
80atc cag gtg gtc ctt aca atg acc aac atg gac cct gtg gac aca gcc
288Ile Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val Asp Thr Ala
85 90 95acg tat tac tgt gca cgg atg ggt ttc act gga acc tac ttt gac
tac 336Thr Tyr Tyr Cys Ala Arg Met Gly Phe Thr Gly Thr Tyr Phe Asp
Tyr 100 105 110tgg ggc cag ggc acc ctg gtc acc gtc tcg agc ggt acg
ggc ggt tca 384Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr
Gly Gly Ser 115 120 125ggc gga acc ggc agc ggc act ggc ggg tcg acg
cag tct gtg ctg act 432Gly Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr
Gln Ser Val Leu Thr 130 135 140cag cca ccc tca gtg tca gtg gcc cca
gga aag acg gcc agg att acc 480Gln Pro Pro Ser Val Ser Val Ala Pro
Gly Lys Thr Ala Arg Ile Thr145 150 155 160tgt ggg gga aac aac att
gga agt aaa agt gtg cac tgg tac cag cag 528Cys Gly Gly Asn Asn Ile
Gly Ser Lys Ser Val His Trp Tyr Gln Gln 165 170 175aag cca ggc cag
gcc cct gtg ctg gtc atc tat tat gat agc gac cgg 576Lys Pro Gly Gln
Ala Pro Val Leu Val Ile Tyr Tyr Asp Ser Asp Arg 180 185 190ccc tca
ggg atc cct gag cga ttc tct ggc tcc aac tct ggg aac acg 624Pro Ser
Gly Ile Pro Glu Arg Phe Ser Gly Ser Asn Ser Gly Asn Thr 195 200
205gcc acc ctg acc atc agc agg gtc gaa gcc ggg gat gag gct gac tat
672Ala Thr Leu Thr Ile Ser Arg Val Glu Ala Gly Asp Glu Ala Asp Tyr
210 215 220tac tgt cag gtg tgg gat agt agt agt gat cat ccc tat gtc
ttc gga 720Tyr Cys Gln Val Trp Asp Ser Ser Ser Asp His Pro Tyr Val
Phe Gly225 230 235 240act ggg acc aag ctg acc gtc cta ggt gcg gcc
gca 756Thr Gly Thr Lys Leu Thr Val Leu Gly Ala Ala Ala 245
250196252PRTArtificial sequenceSynthetic Construct 196Ala Met Ala
Gln Val Thr Leu Lys Glu Ser Gly Pro Thr Leu Val Asn1 5 10 15Pro Thr
Gln Thr Leu Thr Leu Thr Cys Thr Phe Ser Gly Phe Ser Leu 20 25 30Ser
Thr Gly Gly Val Gly Val Gly Trp Phe Arg Gln Pro Pro Gly Lys 35 40
45Ala Leu Glu Trp Leu Ala Arg Ile Asp Trp Asp Asp Asp Lys Tyr Tyr
50 55 60Ser Thr Ser Leu Lys Thr Arg Leu Thr Ile Ser Lys Asp Thr Ser
Lys65 70 75 80Ile Gln Val Val Leu Thr Met Thr Asn Met Asp Pro Val
Asp Thr Ala 85 90 95Thr Tyr Tyr Cys Ala Arg Met Gly Phe Thr Gly Thr
Tyr Phe Asp Tyr 100 105 110Trp Gly Gln Gly Thr Leu Val Thr Val Ser
Ser Gly Thr Gly Gly Ser 115 120 125Gly Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Gln Ser Val Leu Thr 130 135 140Gln Pro Pro Ser Val Ser
Val Ala Pro Gly Lys Thr Ala Arg Ile Thr145 150 155 160Cys Gly Gly
Asn Asn Ile Gly Ser Lys Ser Val His Trp Tyr Gln Gln 165 170 175Lys
Pro Gly Gln Ala Pro Val Leu Val Ile Tyr Tyr Asp Ser Asp Arg 180 185
190Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly Ser Asn Ser Gly Asn Thr
195 200 205Ala Thr Leu Thr Ile Ser Arg Val Glu Ala Gly Asp Glu Ala
Asp Tyr 210 215 220Tyr Cys Gln Val Trp Asp Ser Ser Ser Asp His Pro
Tyr Val Phe Gly225 230 235 240Thr Gly Thr Lys Leu Thr Val Leu Gly
Ala Ala Ala 245 250197747DNAArtificial sequenceSC04-140 197gcc atg
gcc cag atg cag ctg gtg cag tct ggg gga ggc gtg gtc cag 48Ala Met
Ala Gln Met Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15cct
ggg agg tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro
Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25
30agt agc tat ggc atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg
144Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu
35 40 45gag tgg gtg gca gtt ata tta tat gat gga agt aat aaa tac tat
gca 192Glu Trp Val Ala Val Ile Leu Tyr Asp Gly Ser Asn Lys Tyr Tyr
Ala 50 55 60gac tcc gtg aag ggc cga ttc acc atc tcc aga gac aat tcc
aag aac 240Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser
Lys Asn65 70 75 80gcg ttg tat ctg caa atg aac agc ctg aga gct gag
gac acg gct gtg 288Ala Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu
Asp Thr Ala Val 85 90 95tat tac tgt gcg aag gtg acc aac ccc gga gat
gct ttt gat atc tgg 336Tyr Tyr Cys Ala Lys Val Thr Asn Pro Gly Asp
Ala Phe Asp Ile Trp 100 105 110ggc caa ggg acc atg gtc acc gtc tcg
agc ggt acg ggc ggt tca ggc 384Gly Gln Gly Thr Met Val Thr Val Ser
Ser Gly Thr Gly Gly Ser Gly 115 120 125gga acc ggc agc ggc act ggc
ggg tcg acg gac atc cag atg acc cag 432Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Asp Ile Gln Met Thr Gln 130 135 140tct cca tcc tcc ctg
tct gca tct gtc gga gac aga gtc acc atc act 480Ser Pro Ser Ser Leu
Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160tgc cgg
gca agt cag ggc att agc agt gct tta gcc tgg tat cag cag 528Cys Arg
Ala Ser Gln Gly Ile Ser Ser Ala Leu Ala Trp Tyr Gln Gln 165 170
175aaa cca ggg aaa gct cct aag ctc ctg atc tat gat gcc tcc agt ttg
576Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile
Tyr Asp Ala Ser Ser Leu 180 185 190gaa agt ggg gtc cca tca agg ttc
agc ggc agt gga tct ggg aca gat 624Glu Ser Gly Val Pro Ser Arg Phe
Ser Gly Ser Gly Ser Gly Thr Asp 195 200 205ttc act ctc acc atc agc
agc ctg cag cct gaa gat ttt gca act tat 672Phe Thr Leu Thr Ile Ser
Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr 210 215 220tac tgt caa cag
ttt aat agt tac ccg ctc act ttc ggc gga ggg acc 720Tyr Cys Gln Gln
Phe Asn Ser Tyr Pro Leu Thr Phe Gly Gly Gly Thr225 230 235 240aag
gtg gaa atc aaa cgt gcg gcc gca 747Lys Val Glu Ile Lys Arg Ala Ala
Ala 245198249PRTArtificial sequenceSynthetic Construct 198Ala Met
Ala Gln Met Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15Pro
Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25
30Ser Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu
35 40 45Glu Trp Val Ala Val Ile Leu Tyr Asp Gly Ser Asn Lys Tyr Tyr
Ala 50 55 60Asp Ser Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser
Lys Asn65 70 75 80Ala Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu
Asp Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Val Thr Asn Pro Gly Asp
Ala Phe Asp Ile Trp 100 105 110Gly Gln Gly Thr Met Val Thr Val Ser
Ser Gly Thr Gly Gly Ser Gly 115 120 125Gly Thr Gly Ser Gly Thr Gly
Gly Ser Thr Asp Ile Gln Met Thr Gln 130 135 140Ser Pro Ser Ser Leu
Ser Ala Ser Val Gly Asp Arg Val Thr Ile Thr145 150 155 160Cys Arg
Ala Ser Gln Gly Ile Ser Ser Ala Leu Ala Trp Tyr Gln Gln 165 170
175Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile Tyr Asp Ala Ser Ser Leu
180 185 190Glu Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly
Thr Asp 195 200 205Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp
Phe Ala Thr Tyr 210 215 220Tyr Cys Gln Gln Phe Asn Ser Tyr Pro Leu
Thr Phe Gly Gly Gly Thr225 230 235 240Lys Val Glu Ile Lys Arg Ala
Ala Ala 245199744DNAArtificial sequenceSC04-144 199gcc atg gcc cag
gtg cag ctg cag gag ttg ggg gga ggc gtg gtc cag 48Ala Met Ala Gln
Val Gln Leu Gln Glu Leu Gly Gly Gly Val Val Gln1 5 10 15cct ggg agg
tcc ctg aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg
Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30ggt agc
tat ggc atg cac tgg gtc cgc cag gct ccg ggc aag ggg ctg 144Gly Ser
Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag
tgg gtg gca act ata tca tat gat gga agt att aaa gac tat gca 192Glu
Trp Val Ala Thr Ile Ser Tyr Asp Gly Ser Ile Lys Asp Tyr Ala 50 55
60gac tcc gag aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac
240Asp Ser Glu Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80aca ctg tat ctg caa atg aac agc ctg aga gct gag gac
acg gct gtg 288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95tat tac tgt gcg aaa ggg ggg aag act gga gag ttt
gac tac tgg ggc 336Tyr Tyr Cys Ala Lys Gly Gly Lys Thr Gly Glu Phe
Asp Tyr Trp Gly 100 105 110cag gga acc ctg gtc acc gtc tcg agc ggt
acg ggc ggt tca ggc gga 384Gln Gly Thr Leu Val Thr Val Ser Ser Gly
Thr Gly Gly Ser Gly Gly 115 120 125acc ggc agc ggc act ggc ggg tcg
acg gac atc cag ttg acg cag tct 432Thr Gly Ser Gly Thr Gly Gly Ser
Thr Asp Ile Gln Leu Thr Gln Ser 130 135 140cca tcc tcc ctg tct gca
tct gta gga gac aga gtc acc atc act tgc 480Pro Ser Ser Leu Ser Ala
Ser Val Gly Asp Arg Val Thr Ile Thr Cys145 150 155 160cgg gcc agt
cag ggc att agc agt tat tta gcc tgg tat cag caa aaa 528Arg Ala Ser
Gln Gly Ile Ser Ser Tyr Leu Ala Trp Tyr Gln Gln Lys 165 170 175cca
ggg aaa ggc cct aag ctc ctg atc tat gct gca tcc act tta caa 576Pro
Gly Lys Gly Pro Lys Leu Leu Ile Tyr Ala Ala Ser Thr Leu Gln 180 185
190agt ggg gtc cca tca agg ttc agc ggc agt gga tct ggg aca gac ttc
624Ser Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe
195 200 205agt ctc acc atc agt agc ctg cag cct gaa gat tta gca act
tat tac 672Ser Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Leu Ala Thr
Tyr Tyr 210 215 220tgc caa cag tat gat agt tac cct ctc act ttc ggc
gga ggg acc aag 720Cys Gln Gln Tyr Asp Ser Tyr Pro Leu Thr Phe Gly
Gly Gly Thr Lys225 230 235 240gtg gaa atc aaa cgt gcg gcc gca
744Val Glu Ile Lys Arg Ala Ala Ala 245200248PRTArtificial
sequenceSynthetic Construct 200Ala Met Ala Gln Val Gln Leu Gln Glu
Leu Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Gly Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Thr Ile
Ser Tyr Asp Gly Ser Ile Lys Asp Tyr Ala 50 55 60Asp Ser Glu Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Gly Gly Lys Thr Gly Glu Phe Asp Tyr Trp Gly 100 105
110Gln Gly Thr Leu Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly Gly
115 120 125Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu Thr
Gln Ser 130 135 140Pro Ser Ser Leu Ser Ala Ser Val Gly Asp Arg Val
Thr Ile Thr Cys145 150 155 160Arg Ala Ser Gln Gly Ile Ser Ser Tyr
Leu Ala Trp Tyr Gln Gln Lys 165 170 175Pro Gly Lys Gly Pro Lys Leu
Leu Ile Tyr Ala Ala Ser Thr Leu Gln 180 185 190Ser Gly Val Pro Ser
Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp Phe 195 200 205Ser Leu Thr
Ile Ser Ser Leu Gln Pro Glu Asp Leu Ala Thr Tyr Tyr 210 215 220Cys
Gln Gln Tyr Asp Ser Tyr Pro Leu Thr Phe Gly Gly Gly Thr Lys225 230
235 240Val Glu Ile Lys Arg Ala Ala Ala 245201744DNAArtificial
sequenceSC04-146 201gcc atg gcc gaa gtg cag ctg gtg cag tct ggg gga
ggc gtg gtc cag 48Ala Met Ala Glu Val Gln Leu Val Gln Ser Gly Gly
Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg aga ctc tcc tgt gca gcc
tct gga ttc acc ttc 96Pro Gly Arg Ser Leu Arg Leu Ser Cys Ala Ala
Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc atg cac tgg gtc cgc cag
gct ccg ggc aag ggg ctg 144Ser Ser Tyr Gly Met His Trp Val Arg Gln
Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg gca act ata tca tat gat
gga agt att aaa gac tat gca 192Glu Trp Val Ala Thr Ile Ser Tyr Asp
Gly Ser Ile Lys Asp Tyr Ala 50 55 60gac tcc gag gag ggc cga ttc acc
atc tcc aga gac aat tcc aag aac 240Asp Ser Glu Glu Gly Arg Phe Thr
Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80aca ctg tat ctg caa atg
aac agc ctg aga gct gag gac acg gct gtg 288Thr Leu Tyr Leu Gln Met
Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95tat tac tgt gcg aaa
ggg ggg aag act gga gag ttt gac tac tgg ggc 336Tyr Tyr Cys Ala Lys
Gly Gly Lys Thr Gly Glu Phe Asp Tyr Trp Gly 100 105 110cag ggc acc
ctg gtc acc gtc tcg agc ggt acg ggc ggt tca ggc gga 384Gln Gly Thr
Leu Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly Gly 115 120 125acc
ggc agc ggc act ggc ggg tcg acg gat gtt gtg atg act cag tct 432Thr
Gly Ser Gly Thr Gly Gly Ser Thr Asp Val Val Met Thr Gln Ser 130 135
140cca gcc acc ctg tct gtg tct cca ggg gaa agc gcc aca ctc ttc tgc
480Pro Ala Thr Leu Ser Val Ser Pro Gly Glu Ser Ala Thr Leu Phe
Cys145 150 155 160agg gcc agt gag agt gtt tat agc aac ttg gcc tgg
tat cag cac aaa 528Arg Ala Ser Glu Ser Val Tyr Ser Asn Leu Ala Trp
Tyr Gln His Lys 165 170 175cct ggc cgg gct ccc agg ctc ctc atc tat
ggt gca tcc acc agg gcc 576Pro Gly Arg Ala Pro Arg Leu Leu Ile Tyr
Gly Ala Ser Thr Arg Ala 180 185 190act ggt atc cca gcc agg ttc gat
ggc act ggg tct ggg aca gac ttc 624Thr Gly Ile Pro Ala Arg Phe Asp
Gly Thr Gly Ser Gly Thr Asp Phe 195 200 205aca ctc acc atc agc agc
ctg cag tct gaa gat ttt gca gtt tat tac 672Thr Leu Thr Ile Ser Ser
Leu Gln Ser Glu Asp Phe Ala Val Tyr Tyr 210 215 220tgt cag caa tat
aat gac tgg ccg atc acc ttc ggc caa ggg aca cga 720Cys Gln Gln Tyr
Asn Asp Trp Pro Ile Thr Phe Gly Gln Gly Thr Arg225 230 235 240ctg
gag att aaa cgt gcg gcc gca 744Leu Glu Ile Lys Arg Ala Ala Ala
245202248PRTArtificial sequenceSynthetic Construct 202Ala Met Ala
Glu Val Gln Leu Val Gln Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly
Arg Ser Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser
Ser Tyr Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40
45Glu Trp Val Ala Thr Ile Ser Tyr Asp Gly Ser Ile Lys Asp Tyr Ala
50 55 60Asp Ser Glu Glu Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys
Asn65 70 75 80Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp
Thr Ala Val 85 90 95Tyr Tyr Cys Ala Lys Gly Gly Lys Thr Gly Glu Phe
Asp Tyr Trp Gly 100 105 110Gln Gly Thr Leu Val Thr Val Ser Ser Gly
Thr Gly Gly Ser Gly Gly 115 120 125Thr Gly Ser Gly Thr Gly Gly Ser
Thr Asp Val Val Met Thr Gln Ser 130 135 140Pro Ala Thr Leu Ser Val
Ser Pro Gly Glu Ser Ala Thr Leu Phe Cys145 150 155 160Arg Ala Ser
Glu Ser Val Tyr Ser Asn Leu Ala Trp Tyr Gln His Lys 165 170 175Pro
Gly Arg Ala Pro Arg Leu Leu Ile Tyr Gly Ala Ser Thr Arg Ala 180 185
190Thr Gly Ile Pro Ala Arg Phe Asp Gly Thr Gly Ser Gly Thr Asp Phe
195 200 205Thr Leu Thr Ile Ser Ser Leu Gln Ser Glu Asp Phe Ala Val
Tyr Tyr 210 215 220Cys Gln Gln Tyr Asn Asp Trp Pro Ile Thr Phe Gly
Gln Gly Thr Arg225 230 235 240Leu Glu Ile Lys Arg Ala Ala Ala
245203747DNAArtificial sequenceSC04-164 203gcc atg gcc gag gtg cag
ctg gtg gag tct ggg gga ggc gtg gtc cag 48Ala Met Ala Glu Val Gln
Leu Val Glu Ser Gly Gly Gly Val Val Gln1 5 10 15cct ggg agg tcc ctg
aga ctc tcc tgt gca gcc tct gga ttc acc ttc 96Pro Gly Arg Ser Leu
Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30agt agc tat ggc
atg cac tgg gtc cgc cag gct cca ggc aag ggg ctg 144Ser Ser Tyr Gly
Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45gag tgg gtg
gca gtt ata tca tat gat gga agc agt aaa tac tac gca 192Glu Trp Val
Ala Val Ile Ser Tyr Asp Gly Ser Ser Lys Tyr Tyr Ala 50 55 60gac tcc
gtg aag ggc cga ttc acc atc tcc aga gac aat tcc aag aac 240Asp Ser
Val Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75
80acg ctg tat ctg caa atg aac agc ctg aga gct gag gac acg gct gtg
288Thr Leu Tyr Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val
85 90 95tat tac tgt gcg aaa ggg tcc gtc ctc ggt gat gct ttt gat atc
tgg 336Tyr Tyr Cys Ala Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile
Trp 100 105 110ggc caa ggg aca atg gtc acc gtc tcg agc ggt acg ggc
ggt tca ggc 384Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly
Gly Ser Gly 115 120 125gga acc ggc agc ggc act ggc ggg tcg acg gac
atc cag ttg acc cag 432Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp
Ile Gln Leu Thr Gln 130 135 140tct cca tct tct gtg tct gca tct gta
gga gac aga gtc acc atc act 480Ser Pro Ser Ser Val Ser Ala Ser Val
Gly Asp Arg Val Thr Ile Thr145 150 155 160tgt cgg gcg agt cag ggt
att agc agc tgg tta gcc tgg tat cag cag 528Cys Arg Ala Ser Gln Gly
Ile Ser Ser Trp Leu Ala Trp Tyr Gln Gln 165 170 175aaa cca ggg aaa
gcc cct aag ctc ctg atc tat gct gca tcc agt ttg 576Lys Pro Gly Lys
Ala Pro Lys Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185 190caa agt
ggg gtc cca tca agg ttc agc ggc agt gga tct ggg aca gat 624Gln Ser
Gly Val Pro Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200
205ttc act ctc act atc agc agc ctg cag cct gaa gat ttt gca act tac
672Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr
210 215 220tat tgt caa cag gct aac agt ttc ccg ctc act ttc ggc gga
ggg acc 720Tyr Cys Gln Gln Ala Asn Ser Phe Pro Leu Thr Phe Gly Gly
Gly Thr225 230 235 240aaa gtg gat atc aaa cgt gcg gcc gca 747Lys
Val Asp Ile Lys Arg Ala Ala Ala 245204249PRTArtificial
sequenceSynthetic Construct 204Ala Met Ala Glu Val Gln Leu Val Glu
Ser Gly Gly Gly Val Val Gln1 5 10 15Pro Gly Arg Ser Leu Arg Leu Ser
Cys Ala Ala Ser Gly Phe Thr Phe 20 25 30Ser Ser Tyr Gly Met His Trp
Val Arg Gln Ala Pro Gly Lys Gly Leu 35 40 45Glu Trp Val Ala Val Ile
Ser Tyr Asp Gly Ser Ser Lys Tyr Tyr Ala 50 55 60Asp Ser Val Lys Gly
Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn65 70 75 80Thr Leu Tyr
Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala Val 85 90 95Tyr Tyr
Cys Ala Lys Gly Ser Val Leu Gly Asp Ala Phe Asp Ile Trp 100 105
110Gly Gln Gly Thr Met Val Thr Val Ser Ser Gly Thr Gly Gly Ser Gly
115 120 125Gly Thr Gly Ser Gly Thr Gly Gly Ser Thr Asp Ile Gln Leu
Thr Gln 130 135 140Ser Pro Ser Ser Val Ser Ala Ser Val Gly Asp Arg
Val Thr Ile Thr145 150 155 160Cys Arg Ala Ser Gln Gly Ile Ser Ser
Trp Leu Ala Trp Tyr Gln Gln 165 170 175Lys Pro Gly Lys Ala Pro Lys
Leu Leu Ile Tyr Ala Ala Ser Ser Leu 180 185 190Gln Ser Gly Val Pro
Ser Arg Phe Ser Gly Ser Gly Ser Gly Thr Asp 195 200 205Phe Thr Leu
Thr Ile Ser Ser Leu Gln Pro Glu Asp Phe Ala Thr Tyr 210 215 220Tyr
Cys Gln Gln Ala Asn Ser Phe Pro Leu Thr Phe Gly Gly Gly Thr225 230
235 240Lys Val Asp Ile Lys Arg Ala Ala Ala 245205786DNAArtificial
sequenceSO57 205gcc atg gcc cag gtg cag ctg gtg cag agc gga gcc gag
gtg aag aag 48Ala Met Ala Gln Val Gln Leu Val Gln Ser Gly Ala Glu
Val Lys Lys1 5 10 15ccc ggc agc agc gtg aag gtg agc tgc aag gcc agc
ggc ggc acc ttc 96Pro Gly Ser Ser Val Lys Val Ser Cys Lys Ala Ser
Gly Gly Thr Phe 20 25 30aac agg tac acc gtg aac tgg gtg aga cag gcc
cca ggc cag ggc ctg 144Asn Arg Tyr Thr Val Asn Trp Val Arg Gln Ala
Pro Gly Gln Gly Leu 35 40 45gag tgg atg ggc ggc atc atc cct atc ttc
ggc acc gcc aac tac gcc 192Glu Trp Met Gly Gly Ile Ile Pro Ile Phe
Gly Thr Ala Asn Tyr Ala 50 55 60cag aga ttc cag ggc agg ctc acc atc
acc gcc gac gag agc acc agc 240Gln Arg Phe Gln Gly Arg Leu Thr Ile
Thr Ala Asp Glu Ser Thr Ser65
70 75 80acc gcc tac atg gag ctg agc agc ctg aga agc gat gac acc gcc
gtg 288Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg Ser Asp Asp Thr Ala
Val 85 90 95tac ttc tgc gcc agg gag aac ctg gat aac agc ggc acc tac
tac tac 336Tyr Phe Cys Ala Arg Glu Asn Leu Asp Asn Ser Gly Thr Tyr
Tyr Tyr 100 105 110ttc agc ggc tgg ttc gac ccc tgg ggc cag ggc acc
ctg gtg acc gtc 384Phe Ser Gly Trp Phe Asp Pro Trp Gly Gln Gly Thr
Leu Val Thr Val 115 120 125tcg agc ggt acg ggc ggt tca ggc gga acc
ggc agc ggc act ggc ggg 432Ser Ser Gly Thr Gly Gly Ser Gly Gly Thr
Gly Ser Gly Thr Gly Gly 130 135 140tcg acg cag agc gcc ctc acc cag
ccc aga agc gtg agc ggc agc cct 480Ser Thr Gln Ser Ala Leu Thr Gln
Pro Arg Ser Val Ser Gly Ser Pro145 150 155 160ggc cag agc gtg acc
atc agc tgc acc ggc acc agc agc gac atc ggc 528Gly Gln Ser Val Thr
Ile Ser Cys Thr Gly Thr Ser Ser Asp Ile Gly 165 170 175ggc tac aac
ttc gtg agc tgg tat cag cag cac ccc ggc aag gcc cct 576Gly Tyr Asn
Phe Val Ser Trp Tyr Gln Gln His Pro Gly Lys Ala Pro 180 185 190aag
ctc atg atc tac gac gcc acc aag aga ccc agc ggc gtg ccc gac 624Lys
Leu Met Ile Tyr Asp Ala Thr Lys Arg Pro Ser Gly Val Pro Asp 195 200
205aga ttc agc ggc agc aag agc ggc aac acc gcc agc ctc acc atc agc
672Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr Ala Ser Leu Thr Ile Ser
210 215 220gga ctg cag gcc gag gac gag gcc gac tac tac tgc tgc agc
tac gcc 720Gly Leu Gln Ala Glu Asp Glu Ala Asp Tyr Tyr Cys Cys Ser
Tyr Ala225 230 235 240ggc gac tac acc cct ggc gtg gtg ttc ggc gga
ggc acc aag ctt acc 768Gly Asp Tyr Thr Pro Gly Val Val Phe Gly Gly
Gly Thr Lys Leu Thr 245 250 255gtg cta ggt gcg gcc gca 786Val Leu
Gly Ala Ala Ala 260206262PRTArtificial sequenceSynthetic Construct
206Ala Met Ala Gln Val Gln Leu Val Gln Ser Gly Ala Glu Val Lys Lys1
5 10 15Pro Gly Ser Ser Val Lys Val Ser Cys Lys Ala Ser Gly Gly Thr
Phe 20 25 30Asn Arg Tyr Thr Val Asn Trp Val Arg Gln Ala Pro Gly Gln
Gly Leu 35 40 45Glu Trp Met Gly Gly Ile Ile Pro Ile Phe Gly Thr Ala
Asn Tyr Ala 50 55 60Gln Arg Phe Gln Gly Arg Leu Thr Ile Thr Ala Asp
Glu Ser Thr Ser65 70 75 80Thr Ala Tyr Met Glu Leu Ser Ser Leu Arg
Ser Asp Asp Thr Ala Val 85 90 95Tyr Phe Cys Ala Arg Glu Asn Leu Asp
Asn Ser Gly Thr Tyr Tyr Tyr 100 105 110Phe Ser Gly Trp Phe Asp Pro
Trp Gly Gln Gly Thr Leu Val Thr Val 115 120 125Ser Ser Gly Thr Gly
Gly Ser Gly Gly Thr Gly Ser Gly Thr Gly Gly 130 135 140Ser Thr Gln
Ser Ala Leu Thr Gln Pro Arg Ser Val Ser Gly Ser Pro145 150 155
160Gly Gln Ser Val Thr Ile Ser Cys Thr Gly Thr Ser Ser Asp Ile Gly
165 170 175Gly Tyr Asn Phe Val Ser Trp Tyr Gln Gln His Pro Gly Lys
Ala Pro 180 185 190Lys Leu Met Ile Tyr Asp Ala Thr Lys Arg Pro Ser
Gly Val Pro Asp 195 200 205Arg Phe Ser Gly Ser Lys Ser Gly Asn Thr
Ala Ser Leu Thr Ile Ser 210 215 220Gly Leu Gln Ala Glu Asp Glu Ala
Asp Tyr Tyr Cys Cys Ser Tyr Ala225 230 235 240Gly Asp Tyr Thr Pro
Gly Val Val Phe Gly Gly Gly Thr Lys Leu Thr 245 250 255Val Leu Gly
Ala Ala Ala 260207524PRTRabies virusMISC_FEATUREG protein of rabies
virus ERA strain 207Met Val Pro Gln Ala Leu Leu Phe Val Pro Leu Leu
Val Phe Pro Leu1 5 10 15Cys Phe Gly Lys Phe Pro Ile Tyr Thr Ile Leu
Asp Lys Leu Gly Pro 20 25 30Trp Ser Pro Ile Asp Ile His His Leu Ser
Cys Pro Asn Asn Leu Val 35 40 45Val Glu Asp Glu Gly Cys Thr Asn Leu
Ser Gly Phe Ser Tyr Met Glu 50 55 60Leu Lys Val Gly Tyr Ile Leu Ala
Ile Lys Met Asn Gly Phe Thr Cys65 70 75 80Thr Gly Val Val Thr Glu
Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr 85 90 95Val Thr Thr Thr Phe
Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala 100 105 110Cys Arg Ala
Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu 115 120 125Glu
Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val 130 135
140Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala
Asp145 150 155 160Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val
Phe Pro Ser Gly 165 170 175Lys Cys Ser Gly Val Ala Val Ser Ser Thr
Tyr Cys Ser Thr Asn His 180 185 190Asp Tyr Thr Ile Trp Met Pro Glu
Asn Pro Arg Leu Gly Met Ser Cys 195 200 205Asp Ile Phe Thr Asn Ser
Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu 210 215 220Thr Cys Gly Phe
Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly225 230 235 240Ala
Cys Lys Leu Lys Leu Cys Gly Val Leu Gly Leu Arg Leu Met Asp 245 250
255Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro
260 265 270Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu
Ile Glu 275 280 285His Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu
Glu Cys Leu Asp 290 295 300Ala Leu Glu Ser Ile Met Thr Thr Lys Ser
Val Ser Phe Arg Arg Leu305 310 315 320Ser His Leu Arg Lys Leu Val
Pro Gly Phe Gly Lys Ala Tyr Thr Ile 325 330 335Phe Asn Lys Thr Leu
Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg 340 345 350Thr Trp Asn
Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly 355 360 365Arg
Cys His Pro His Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu 370 375
380Gly Pro Asp Gly Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu
Leu385 390 395 400Gln Gln His Met Glu Leu Leu Glu Ser Ser Val Ile
Pro Leu Val His 405 410 415Pro Leu Ala Asp Pro Ser Thr Val Phe Lys
Asp Gly Asp Glu Ala Glu 420 425 430Asp Phe Val Glu Val His Leu Pro
Asp Val His Asn Gln Val Ser Gly 435 440 445Val Asp Leu Gly Leu Pro
Asn Trp Gly Lys Tyr Val Leu Leu Ser Ala 450 455 460Gly Ala Leu Thr
Ala Leu Met Leu Ile Ile Phe Leu Met Thr Cys Cys465 470 475 480Arg
Arg Val Asn Arg Ser Glu Pro Thr Gln His Asn Leu Arg Gly Thr 485 490
495Gly Arg Glu Val Ser Val Thr Pro Gln Ser Gly Lys Ile Ile Ser Ser
500 505 510Trp Glu Ser His Lys Ser Gly Gly Glu Thr Arg Leu 515
52020823DNAArtificial sequencePrimer HuVlambda1A 208cagtctgtgc
tgactcagcc acc 2320923DNAArtificial sequencePrimer HuVlambda1B
209cagtctgtgy tgacgcagcc gcc 2321023DNAArtificial sequencePrimer
HuVlambda1C 210cagtctgtcg tgacgcagcc gcc 2321121DNAArtificial
sequencePrimer HuVlambda2 211cartctgccc tgactcagcc t
2121223DNAArtificial sequencePrimer HuVlambda3A 212tcctatgwgc
tgactcagcc acc 2321323DNAArtificial sequencePrimer HuVlambda3B
213tcttctgagc tgactcagga ccc 2321423DNAArtificial sequencePrimer
HuVlambda4 214cacgttatac tgactcaacc gcc 2321523DNAArtificial
sequencePrimer HuVlambda5 215caggctgtgc tgactcagcc gtc
2321623DNAArtificial sequencePrimer HuVlambda6 216aattttatgc
tgactcagcc cca 2321723DNAArtificial sequencePrimer HuVlambda7/8
217cagrctgtgg tgacycagga gcc 2321823DNAArtificial sequencePrimer
HuVlambda9 218cwgcctgtgc tgactcagcc mcc 2321923DNAArtificial
sequencePrimer HuVkappa1B 219gacatccagw tgacccagtc tcc
2322023DNAArtificial sequencePrimer HuVkappa2 220gatgttgtga
tgactcagtc tcc 2322123DNAArtificial sequencePrimer HuVkappa3
221gaaattgtgw tgacrcagtc tcc 2322223DNAArtificial sequencePrimer
HuVkappa4 222gatattgtga tgacccacac tcc 2322323DNAArtificial
sequencePrimer HuVkappa5 223gaaacgacac tcacgcagtc tcc
2322423DNAArtificial sequencePrimer HuVkappa6 224gaaattgtgc
tgactcagtc tcc 2322541DNAArtificial sequencePrimer HuVkappa1B-SalI
225tgagcacaca ggtcgacgga catccagwtg acccagtctc c
4122641DNAArtificial sequencePrimer HuVkappa2-SalI 226tgagcacaca
ggtcgacgga tgttgtgatg actcagtctc c 4122741DNAArtificial
sequencePrimer HuVkappa3B-SalI 227tgagcacaca ggtcgacgga aattgtgwtg
acrcagtctc c 4122841DNAArtificial sequencePrimer HuVkappa4B-SalI
228tgagcacaca ggtcgacgga tattgtgatg acccacactc c
4122941DNAArtificial sequencePrimer HuVkappa5-SalI 229tgagcacaca
ggtcgacgga aacgacactc acgcagtctc c 4123041DNAArtificial
sequencePrimer HuVkappa6-SalI 230tgagcacaca ggtcgacgga aattgtgctg
actcagtctc c 4123148DNAArtificial sequencePrimer HuJkappa1-NotI
231gagtcattct cgacttgcgg ccgcacgttt gatttccacc ttggtccc
4823248DNAArtificial sequencePrimer HuJkappa2-NotI 232gagtcattct
cgacttgcgg ccgcacgttt gatctccagc ttggtccc 4823348DNAArtificial
sequencePrimer HuJkappa3-NotI 233gagtcattct cgacttgcgg ccgcacgttt
gatatccact ttggtccc 4823448DNAArtificial sequencePrimer
HuJkappa4-NotI 234gagtcattct cgacttgcgg ccgcacgttt gatctccacc
ttggtccc 4823548DNAArtificial sequencePrimer HuJkappa5-NotI
235gagtcattct cgacttgcgg ccgcacgttt aatctccagt cgtgtccc
4823641DNAArtificial sequencePrimer HuVlambda1A-SalI 236tgagcacaca
ggtcgacgca gtctgtgctg actcagccac c 4123741DNAArtificial
sequencePrimer HuVlambda1B-SalI 237tgagcacaca ggtcgacgca gtctgtgytg
acgcagccgc c 4123841DNAArtificial sequencePrimer HuVlambda1C-SalI
238tgagcacaca ggtcgacgca gtctgtcgtg acgcagccgc c
4123939DNAArtificial sequencePrimer HuVlambda2-SalI 239tgagcacaca
ggtcgacgca rtctgccctg actcagcct 3924041DNAArtificial sequencePrimer
HuVlambda3A-SalI 240tgagcacaca ggtcgacgtc ctatgwgctg actcagccac c
4124141DNAArtificial sequencePrimer HuVlambda3B-SalI 241tgagcacaca
ggtcgacgtc ttctgagctg actcaggacc c 4124241DNAArtificial
sequencePrimer HuVlambda4-SalI 242tgagcacaca ggtcgacgca cgttatactg
actcaaccgc c 4124341DNAArtificial sequencePrimer HuVlambda5-SalI
243tgagcacaca ggtcgacgca ggctgtgctg actcagccgt c
4124441DNAArtificial sequencePrimer HuVlambda6-SalI 244tgagcacaca
ggtcgacgaa ttttatgctg actcagcccc a 4124541DNAArtificial
sequencePrimer HuVlambda7/8-SalI 245tgagcacaca ggtcgacgca
grctgtggtg acycaggagc c 4124641DNAArtificial sequencePrimer
HuVlambda9-SalI 246tgagcacaca ggtcgacgcw gcctgtgctg actcagccmc c
4124748DNAArtificial sequencePrimer HuJlambda1-NotI 247gagtcattct
cgacttgcgg ccgcacctag gacggtgacc ttggtccc 4824848DNAArtificial
sequencePrimer HuJlambda2/3-NotI 248gagtcattct cgacttgcgg
ccgcacctag gacggtcagc ttggtccc 4824948DNAArtificial sequencePrimer
HuJlambda4/5-NotI 249gagtcattct cgacttgcgg ccgcacytaa aacggtgagc
tgggtccc 4825023DNAArtificial sequencePrimer HuVH1B/7A
250cagrtgcagc tggtgcartc tgg 2325123DNAArtificial sequencePrimer
HuVH1C 251saggtccagc tggtrcagtc tgg 2325223DNAArtificial
sequencePrimer HuVH2B 252saggtgcagc tggtggagtc tgg
2325323DNAArtificial sequencePrimer HuVH3B 253saggtgcagc tggtggagtc
tgg 2325423DNAArtificial sequencePrimer HuVH3C 254gaggtgcagc
tggtggagwc ygg 2325523DNAArtificial sequencePrimer HuVH4B
255caggtgcagc tacagcagtg ggg 2325623DNAArtificial sequencePrimer
HuVH4C 256cagstgcagc tgcaggagtc sgg 2325723DNAArtificial
sequencePrimer HuVH5B 257gargtgcagc tggtgcagtc tgg
2325823DNAArtificial sequencePrimer HuVH6A 258caggtacagc tgcagcagtc
agg 2325956DNAArtificial sequencePrimer HuVH1B/7A-SfiI
259gtcctcgcaa ctgcggccca gccggccatg gcccagrtgc agctggtgca rtctgg
5626056DNAArtificial sequencePrimer HuVH1C-SfiI 260gtcctcgcaa
ctgcggccca gccggccatg gccsaggtcc agctggtrca gtctgg
5626156DNAArtificial sequencePrimer HuVH2B-SfiI 261gtcctcgcaa
ctgcggccca gccggccatg gcccagrtca ccttgaagga gtctgg
5626256DNAArtificial sequencePrimer HuVH3B-SfiI 262gtcctcgcaa
ctgcggccca gccggccatg gccsaggtgc agctggtgga gtctgg
5626356DNAArtificial sequencePrimer HuVH3C-SfiI 263gtcctcgcaa
ctgcggccca gccggccatg gccgaggtgc agctggtgga gwcygg
5626456DNAArtificial sequencePrimer HuVH4B-SfiI 264gtcctcgcaa
ctgcggccca gccggccatg gcccaggtgc agctacagca gtgggg
5626556DNAArtificial sequencePrimer HuVH4C-SfiI 265gtcctcgcaa
ctgcggccca gccggccatg gcccagstgc agctgcagga gtcsgg
5626656DNAArtificial sequencePrimer HuVH5B-SfiI 266gtcctcgcaa
ctgcggccca gccggccatg gccgargtgc agctggtgca gtctgg
5626756DNAArtificial sequencePrimer HuVH6A-SfiI 267gtcctcgcaa
ctgcggccca gccggccatg gcccaggtac agctgcagca gtcagg
5626836DNAArtificial sequencePrimer HuJH1/2-XhoI 268gagtcattct
cgactcgaga cggtgaccag ggtgcc 3626936DNAArtificial sequencePrimer
HuJH3-XhoI 269gagtcattct cgactcgaga cggtgaccat tgtccc
3627036DNAArtificial sequencePrimer HuJH4/5-XhoI 270gagtcattct
cgactcgaga cggtgaccag ggttcc 3627136DNAArtificial sequencePrimer
HuJH6-XhoI 271gagtcattct cgactcgaga cggtgaccgt ggtccc
36272381DNAArtificial sequenceHeavy chain variable region of CR57
272caggtgcagc tggtgcagag cggagccgag gtgaagaagc ccggcagcag
cgtgaaggtg 60agctgcaagg ccagcggcgg caccttcaac aggtacaccg tgaactgggt
gagacaggcc 120ccaggccagg gcctggagtg gatgggcggc atcatcccta
tcttcggcac cgccaactac 180gcccagagat tccagggcag gctcaccatc
accgccgacg agagcaccag caccgcctac 240atggagctga gcagcctgag
aagcgatgac accgccgtgt acttctgcgc cagggagaac 300ctggataaca
gcggcaccta ctactacttc agcggctggt tcgacccctg gggccagggc
360accctggtga ccgtgagctc a 381273127PRTArtificial sequenceHeavy
chain variable region of CR57 273Gln Val Gln Leu Val Gln Ser Gly
Ala Glu Val Lys Lys Pro Gly Ser1 5 10 15Ser Val Lys Val Ser Cys Lys
Ala Ser Gly Gly Thr Phe Asn Arg Tyr 20 25 30Thr Val Asn Trp Val Arg
Gln Ala Pro Gly Gln Gly Leu Glu Trp Met 35 40 45Gly Gly Ile Ile Pro
Ile Phe Gly Thr Ala Asn Tyr Ala Gln Arg Phe 50 55 60Gln Gly Arg Leu
Thr Ile Thr Ala Asp Glu Ser Thr Ser Thr Ala Tyr65 70 75 80Met Glu
Leu Ser Ser Leu Arg Ser Asp Asp Thr Ala Val Tyr Phe Cys 85 90 95Ala
Arg Glu Asn Leu Asp Asn Ser Gly Thr Tyr Tyr Tyr Phe Ser Gly 100 105
110Trp Phe Asp Pro Trp Gly Gln Gly Thr Leu Val Thr Val Ser Ser 115
120 125274336DNAArtificial sequenceLight chain variable region of
CR57 274cagagcgccc tcacccagcc cagaagcgtg agcggcagcc ctggccagag
cgtgaccatc
60agctgcaccg gcaccagcag cgacatcggc ggctacaact tcgtgagctg gtatcagcag
120caccccggca aggcccctaa gctcatgatc tacgacgcca ccaagagacc
cagcggcgtg 180cccgacagat tcagcggcag caagagcggc aacaccgcca
gcctcaccat cagcggactg 240caggccgagg acgaggccga ctactactgc
tgcagctacg ccggcgacta cacccctggc 300gtggtgttcg gcggaggcac
caagcttacc gtccta 336275112PRTArtificial sequenceLight chain
variable region of CR57 275Gln Ser Ala Leu Thr Gln Pro Arg Ser Val
Ser Gly Ser Pro Gly Gln1 5 10 15Ser Val Thr Ile Ser Cys Thr Gly Thr
Ser Ser Asp Ile Gly Gly Tyr 20 25 30Asn Phe Val Ser Trp Tyr Gln Gln
His Pro Gly Lys Ala Pro Lys Leu 35 40 45Met Ile Tyr Asp Ala Thr Lys
Arg Pro Ser Gly Val Pro Asp Arg Phe 50 55 60Ser Gly Ser Lys Ser Gly
Asn Thr Ala Ser Leu Thr Ile Ser Gly Leu65 70 75 80Gln Ala Glu Asp
Glu Ala Asp Tyr Tyr Cys Cys Ser Tyr Ala Gly Asp 85 90 95Tyr Thr Pro
Gly Val Val Phe Gly Gly Gly Thr Lys Leu Thr Val Leu 100 105
11027612PRTArtificial sequenceCDR3 of CRJB 276Arg Gln His Ile Ser
Ser Phe Pro Trp Phe Asp Ser1 5 102776778DNAArtificial
sequenceVector pSyn-C03-HCgamma1 277gacggatcgg gagatctccc
gatcccctat ggtgcactct cagtacaatc tgctctgatg 60ccgcatagtt aagccagtat
ctgctccctg cttgtgtgtt ggaggtcgct gagtagtgcg 120cgagcaaaat
ttaagctaca acaaggcaag gcttgaccga caattgcatg aagaatctgc
180ttagggttag gcgttttgcg ctgcttcgct aggtggtcaa tattggccat
tagccatatt 240attcattggt tatatagcat aaatcaatat tggctattgg
ccattgcata cgttgtatcc 300atatcataat atgtacattt atattggctc
atgtccaaca ttaccgccat gttgacattg 360attattgact agttattaat
agtaatcaat tacggggtca ttagttcata gcccatatat 420ggagttccgc
gttacataac ttacggtaaa tggcccgcct ggctgaccgc ccaacgaccc
480ccgcccattg acgtcaataa tgacgtatgt tcccatagta acgccaatag
ggactttcca 540ttgacgtcaa tgggtggagt atttacggta aactgcccac
ttggcagtac atcaagtgta 600tcatatgcca agtacgcccc ctattgacgt
caatgacggt aaatggcccg cctggcatta 660tgcccagtac atgaccttat
gggactttcc tacttggcag tacatctacg tattagtcat 720cgctattacc
atggtgatgc ggttttggca gtacatcaat gggcgtggat agcggtttga
780ctcacgggga tttccaagtc tccaccccat tgacgtcaat gggagtttgt
tttggcacca 840aaatcaacgg gactttccaa aatgtcgtaa caactccgcc
ccattgacgc aaatgggcgg 900taggcgtgta cggtgggagg tctatataag
cagagctcgt ttagtgaacc gtcagatcgc 960ctggagacgc catccacgct
gttttgacct ccatagaaga caccgggacc gatccagcct 1020ccgcggccgg
gaacggtgca ttggaagctg gcctggatgg cctgactctc ttaggtagcc
1080ttgcagaagt tggtcgtgag gcactgggca ggtaagtatc aaggttacaa
gacaggttta 1140aggagatcaa tagaaactgg gcttgtcgag acagagaaga
ctcttgcgtt tctgataggc 1200acctattggt cttactgaca tccactttgc
ctttctctcc acaggtgtcc actcccagtt 1260caattacagc tcgccaccat
ggcctgcccc ggcttcctgt gggccctggt gatcagcacc 1320tgcctggaat
tcagcatgag cagcgctagc accaagggcc ccagcgtgtt ccccctggcc
1380cccagcagca agagcaccag cggcggcaca gccgccctgg gctgcctggt
gaaggactac 1440ttccccgagc ccgtgaccgt gagctggaac agcggcgcct
tgaccagcgg cgtgcacacc 1500ttccccgccg tgctgcagag cagcggcctg
tacagcctga gcagcgtggt gaccgtgccc 1560agcagcagcc tgggcaccca
gacctacatc tgcaacgtga accacaagcc cagcaacacc 1620aaggtggaca
aacgcgtgga gcccaagagc tgcgacaaga cccacacctg ccccccctgc
1680cctgcccccg agctgctggg cggaccctcc gtgttcctgt tcccccccaa
gcccaaggac 1740accctcatga tcagccggac ccccgaggtg acctgcgtgg
tggtggacgt gagccacgag 1800gaccccgagg tgaagttcaa ctggtacgtg
gacggcgtgg aggtgcacaa cgccaagacc 1860aagccccggg aggagcagta
caacagcacc taccgggtgg tgagcgtgct caccgtgctg 1920caccaggact
ggctgaacgg caaggagtac aagtgcaagg tgagcaacaa ggccctgcct
1980gcccccatcg agaagaccat cagcaaggcc aagggccagc cccgggagcc
ccaggtgtac 2040accctgcccc ccagccggga ggagatgacc aagaaccagg
tgtccctcac ctgtctggtg 2100aagggcttct accccagcga catcgccgtg
gagtgggaga gcaacggcca gcccgagaac 2160aactacaaga ccaccccccc
tgtgctggac agcgacggca gcttcttcct gtacagcaag 2220ctcaccgtgg
acaagagccg gtggcagcag ggcaacgtgt tcagctgcag cgtgatgcac
2280gaggccctgc acaaccacta cacccagaag agcctgagcc tgagccccgg
caagtgataa 2340tctagagggc ccgtttaaac ccgctgatca gcctcgactg
tgccttctag ttgccagcca 2400tctgttgttt gcccctcccc cgtgccttcc
ttgaccctgg aaggtgccac tcccactgtc 2460ctttcctaat aaaatgagga
aattgcatcg cattgtctga gtaggtgtca ttctattctg 2520gggggtgggg
tggggcagga cagcaagggg gaggattggg aagacaatag caggcatgct
2580ggggatgcgg tgggctctat ggcttctgag gcggaaagaa ccagctgggg
ctctaggggg 2640tatccccacg cgccctgtag cggcgcatta agcgcggcgg
gtgtggtggt tacgcgcagc 2700gtgaccgcta cacttgccag cgccctagcg
cccgctcctt tcgctttctt cccttccttt 2760ctcgccacgt tcgccggctt
tccccgtcaa gctctaaatc gggggctccc tttagggttc 2820cgatttagtg
ctttacggca cctcgacccc aaaaaacttg attagggtga tggttcacgt
2880agtgggccat cgccctgata gacggttttt cgccctttga cgttggagtc
cacgttcttt 2940aatagtggac tcttgttcca aactggaaca acactcaacc
ctatctcggt ctattctttt 3000gatttataag ggattttgcc gatttcggcc
tattggttaa aaaatgagct gatttaacaa 3060aaatttaacg cgaattaatt
ctgtggaatg tgtgtcagtt agggtgtgga aagtccccag 3120gctccccagc
aggcagaagt atgcaaagca tgcatctcaa ttagtcagca accaggtgtg
3180gaaagtcccc aggctcccca gcaggcagaa gtatgcaaag catgcatctc
aattagtcag 3240caaccatagt cccgccccta actccgccca tcccgcccct
aactccgccc agttccgccc 3300attctccgcc ccatggctga ctaatttttt
ttatttatgc agaggccgag gccgcctctg 3360cctctgagct attccagaag
tagtgaggag gcttttttgg aggcctaggc ttttgcaaaa 3420agctcccggg
agcttgtata tccattttcg gatctgatca agagacagga tgaggatcgt
3480ttcgcatgat tgaacaagat ggattgcacg caggttctcc ggccgcttgg
gtggagaggc 3540tattcggcta tgactgggca caacagacaa tcggctgctc
tgatgccgcc gtgttccggc 3600tgtcagcgca ggggcgcccg gttctttttg
tcaagaccga cctgtccggt gccctgaatg 3660aactgcagga cgaggcagcg
cggctatcgt ggctggccac gacgggcgtt ccttgcgcag 3720ctgtgctcga
cgttgtcact gaagcgggaa gggactggct gctattgggc gaagtgccgg
3780ggcaggatct cctgtcatct caccttgctc ctgccgagaa agtatccatc
atggctgatg 3840caatgcggcg gctgcatacg cttgatccgg ctacctgccc
attcgaccac caagcgaaac 3900atcgcatcga gcgagcacgt actcggatgg
aagccggtct tgtcgatcag gatgatctgg 3960acgaagagca tcaggggctc
gcgccagccg aactgttcgc caggctcaag gcgcgcatgc 4020ccgacggcga
ggatctcgtc gtgacccatg gcgatgcctg cttgccgaat atcatggtgg
4080aaaatggccg cttttctgga ttcatcgact gtggccggct gggtgtggcg
gatcgctatc 4140aggacatagc gttggctacc cgtgatattg ctgaagagct
tggcggcgaa tgggctgacc 4200gcttcctcgt gctttacggt atcgccgctc
ccgattcgca gcgcatcgcc ttctatcgcc 4260ttcttgacga gttcttctga
gcgggactct ggggttcgaa atgaccgacc aagcgacgcc 4320caacctgcca
tcacgagatt tcgattccac cgccgccttc tatgaaaggt tgggcttcgg
4380aatcgttttc cgggacgccg gctggatgat cctccagcgc ggggatctca
tgctggagtt 4440cttcgcccac cccaacttgt ttattgcagc ttataatggt
tacaaataaa gcaatagcat 4500cacaaatttc acaaataaag catttttttc
actgcattct agttgtggtt tgtccaaact 4560catcaatgta tcttatcatg
tctgtatacc gtcgacctct agctagagct tggcgtaatc 4620atggtcatag
ctgtttcctg tgtgaaattg ttatccgctc acaattccac acaacatacg
4680agccggaagc ataaagtgta aagcctgggg tgcctaatga gtgagctaac
tcacattaat 4740tgcgttgcgc tcactgcccg ctttccagtc gggaaacctg
tcgtgccagc tgcattaatg 4800aatcggccaa cgcgcgggga gaggcggttt
gcgtattggg cgctcttccg cttcctcgct 4860cactgactcg ctgcgctcgg
tcgttcggct gcggcgagcg gtatcagctc actcaaaggc 4920ggtaatacgg
ttatccacag aatcagggga taacgcagga aagaacatgt gagcaaaagg
4980ccagcaaaag gccaggaacc gtaaaaaggc cgcgttgctg gcgtttttcc
ataggctccg 5040cccccctgac gagcatcaca aaaatcgacg ctcaagtcag
aggtggcgaa acccgacagg 5100actataaaga taccaggcgt ttccccctgg
aagctccctc gtgcgctctc ctgttccgac 5160cctgccgctt accggatacc
tgtccgcctt tctcccttcg ggaagcgtgg cgctttctca 5220tagctcacgc
tgtaggtatc tcagttcggt gtaggtcgtt cgctccaagc tgggctgtgt
5280gcacgaaccc cccgttcagc ccgaccgctg cgccttatcc ggtaactatc
gtcttgagtc 5340caacccggta agacacgact tatcgccact ggcagcagcc
actggtaaca ggattagcag 5400agcgaggtat gtaggcggtg ctacagagtt
cttgaagtgg tggcctaact acggctacac 5460tagaagaaca gtatttggta
tctgcgctct gctgaagcca gttaccttcg gaaaaagagt 5520tggtagctct
tgatccggca aacaaaccac cgctggtagc ggtttttttg tttgcaagca
5580gcagattacg cgcagaaaaa aaggatctca agaagatcct ttgatctttt
ctacggggtc 5640tgacgctcag tggaacgaaa actcacgtta agggattttg
gtcatgagat tatcaaaaag 5700gatcttcacc tagatccttt taaattaaaa
atgaagtttt aaatcaatct aaagtatata 5760tgagtaaact tggtctgaca
gttaccaatg cttaatcagt gaggcaccta tctcagcgat 5820ctgtctattt
cgttcatcca tagttgcctg actccccgtc gtgtagataa ctacgatacg
5880ggagggctta ccatctggcc ccagtgctgc aatgataccg cgagacccac
gctcaccggc 5940tccagattta tcagcaataa accagccagc cggaagggcc
gagcgcagaa gtggtcctgc 6000aactttatcc gcctccatcc agtctattaa
ttgttgccgg gaagctagag taagtagttc 6060gccagttaat agtttgcgca
acgttgttgc cattgctaca ggcatcgtgg tgtcacgctc 6120gtcgtttggt
atggcttcat tcagctccgg ttcccaacga tcaaggcgag ttacatgatc
6180ccccatgttg tgcaaaaaag cggttagctc cttcggtcct ccgatcgttg
tcagaagtaa 6240gttggccgca gtgttatcac tcatggttat ggcagcactg
cataattctc ttactgtcat 6300gccatccgta agatgctttt ctgtgactgg
tgagtactca accaagtcat tctgagaata 6360gtgtatgcgg cgaccgagtt
gctcttgccc ggcgtcaata cgggataata ccgcgccaca 6420tagcagaact
ttaaaagtgc tcatcattgg aaaacgttct tcggggcgaa aactctcaag
6480gatcttaccg ctgttgagat ccagttcgat gtaacccact cgtgcaccca
actgatcttc 6540agcatctttt actttcacca gcgtttctgg gtgagcaaaa
acaggaaggc aaaatgccgc 6600aaaaaaggga ataagggcga cacggaaatg
ttgaatactc atactcttcc tttttcaata 6660ttattgaagc atttatcagg
gttattgtct catgagcgga tacatatttg aatgtattta 6720gaaaaataaa
caaatagggg ttccgcgcac atttccccga aaagtgccac ctgacgtc
67782786283DNAArtificial sequenceVector pSyn-C04-Clambda
278gacggatcgg gagatctccc gatcccctat ggtgcactct cagtacaatc
tgctctgatg 60ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt ggaggtcgct
gagtagtgcg 120cgagcaaaat ttaagctaca acaaggcaag gcttgaccga
caattgttaa ttaacatgaa 180gaatctgctt agggttaggc gttttgcgct
gcttcgctag gtggtcaata ttggccatta 240gccatattat tcattggtta
tatagcataa atcaatattg gctattggcc attgcatacg 300ttgtatccat
atcataatat gtacatttat attggctcat gtccaacatt accgccatgt
360tgacattgat tattgactag ttattaatag taatcaatta cggggtcatt
agttcatagc 420ccatatatgg agttccgcgt tacataactt acggtaaatg
gcccgcctgg ctgaccgccc 480aacgaccccc gcccattgac gtcaataatg
acgtatgttc ccatagtaac gccaataggg 540actttccatt gacgtcaatg
ggtggagtat ttacggtaaa ctgcccactt ggcagtacat 600caagtgtatc
atatgccaag tacgccccct attgacgtca atgacggtaa atggcccgcc
660tggcattatg cccagtacat gaccttatgg gactttccta cttggcagta
catctacgta 720ttagtcatcg ctattaccat ggtgatgcgg ttttggcagt
acatcaatgg gcgtggatag 780cggtttgact cacggggatt tccaagtctc
caccccattg acgtcaatgg gagtttgttt 840tggcaccaaa atcaacggga
ctttccaaaa tgtcgtaaca actccgcccc attgacgcaa 900atgggcggta
ggcgtgtacg gtgggaggtc tatataagca gagctcgttt agtgaaccgt
960cagatcgcct ggagacgcca tccacgctgt tttgacctcc atagaagaca
ccgggaccga 1020tccagcctcc gcggccggga acggtgcatt ggaatcgatg
actctcttag gtagccttgc 1080agaagttggt cgtgaggcac tgggcaggta
agtatcaagg ttacaagaca ggtttaagga 1140gatcaataga aactgggctt
gtcgagacag agaagactct tgcgtttctg ataggcacct 1200attggtctta
ctgacatcca ctttgccttt ctctccacag gtgtccactc ccagttcaat
1260tacagctcgc caccatggcc tgccccggct tcctgtgggc cctggtgatc
agcacctgcc 1320tcgagatccc cggaccgcgg ccgcaagctt accgtgctgg
gccagcccaa ggccgctccc 1380agcgtgaccc tgttcccccc ctcctccgag
gagctgcagg ccaacaaggc caccctggtg 1440tgcctcatca gcgacttcta
ccctggcgcc gtgaccgtgg cctggaaggc cgacagcagc 1500cccgtgaagg
ccggcgtgga gaccaccacc cccagcaagc agagcaacaa caagtacgcc
1560gccagcagct acctgagcct cacccccgag cagtggaaga gccaccggag
ctacagctgc 1620caggtgaccc acgagggcag caccgtggag aagaccgtgg
cccccaccga gtgcagctaa 1680tagacttaag tttaaaccgc tgatcagcct
cgactgtgcc ttctagttgc cagccatctg 1740ttgtttgccc ctcccccgtg
ccttccttga ccctggaagg tgccactccc actgtccttt 1800cctaataaaa
tgaggaaatt gcatcgcatt gtctgagtag gtgtcattct attctggggg
1860gtggggtggg gcaggacagc aagggggagg attgggaaga caatagcagg
catgctgggg 1920atgcggtggg ctctatggct tctgaggcgg aaagaaccag
ctggggctct agggggtatc 1980cccacgcgcc ctgtagcggc gcattaagcg
cggcgggtgt ggtggttacg cgcagcgtga 2040ccgctacact tgccagcgcc
ctagcgcccg ctcctttcgc tttcttccct tcctttctcg 2100ccacgttcgc
cggctttccc cgtcaagctc taaatcgggg gctcccttta gggttccgat
2160ttagtgcttt acggcacctc gaccccaaaa aacttgatta gggtgatggt
tcacgtagtg 2220ggccatcgcc ctgatagacg gtttttcgcc ctttgacgtt
ggagtccacg ttctttaata 2280gtggactctt gttccaaact ggaacaacac
tcaaccctat ctcggtctat tcttttgatt 2340tataagggat tttggccatt
tcggcctatt ggttaaaaaa tgagctgatt taacaaaaat 2400ttaacgcgaa
ttaattctgt ggaatgtgtg tcagttaggg tgtggaaagt ccccaggctc
2460cccagcaggc agaagtatgc aaagcatgca tctcaattag tcagcaacca
ggtgtggaaa 2520gtccccaggc tccccagcag gcagaagtat gcaaagcatg
catctcaatt agtcagcaac 2580catagtcccg cccctaactc cgcccatccc
gcccctaact ccgcccagtt ccgcccattc 2640tccgccccat ggctgactaa
ttttttttat ttatgcagag gccgaggccg cctctgcctc 2700tgagctattc
cagaagtagt gaggaggctt ttttggaggc ctaggctttt gcaaaaagct
2760cccgggagct tgtatatcca ttttcggatc tgatcagcac gtgatgaaaa
agcctgaact 2820caccgcgacg tctgtcgaga agtttctgat cgaaaagttc
gacagcgtct ccgacctgat 2880gcagctctcg gagggcgaag aatctcgtgc
tttcagcttc gatgtaggag ggcgtggata 2940tgtcctgcgg gtaaatagct
gcgccgatgg tttctacaaa gatcgttatg tttatcggca 3000ctttgcatcg
gccgcgctcc cgattccgga agtgcttgac attggggaat tcagcgagag
3060cctgacctat tgcatctccc gccgtgcaca gggtgtcacg ttgcaagacc
tgcctgaaac 3120cgaactgccc gctgttctgc agccggtcgc ggaggccatg
gatgcgatcg ctgcggccga 3180tcttagccag acgagcgggt tcggcccatt
cggaccgcaa ggaatcggtc aatacactac 3240atggcgtgat ttcatatgcg
cgattgctga tccccatgtg tatcactggc aaactgtgat 3300ggacgacacc
gtcagtgcgt ccgtcgcgca ggctctcgat gagctgatgc tttgggccga
3360ggactgcccc gaagtccggc acctcgtgca cgcggatttc ggctccaaca
atgtcctgac 3420ggacaatggc cgcataacag cggtcattga ctggagcgag
gcgatgttcg gggattccca 3480atacgaggtc gccaacatct tcttctggag
gccgtggttg gcttgtatgg agcagcagac 3540gcgctacttc gagcggaggc
atccggagct tgcaggatcg ccgcggctcc gggcgtatat 3600gctccgcatt
ggtcttgacc aactctatca gagcttggtt gacggcaatt tcgatgatgc
3660agcttgggcg cagggtcgat gcgacgcaat cgtccgatcc ggagccggga
ctgtcgggcg 3720tacacaaatc gcccgcagaa gcgcggccgt ctggaccgat
ggctgtgtag aagtactcgc 3780cgatagtgga aaccgacgcc ccagcactcg
tccgagggca aaggaatagc acgtgctacg 3840agatttcgat tccaccgccg
ccttctatga aaggttgggc ttcggaatcg ttttccggga 3900cgccggctgg
atgatcctcc agcgcgggga tctcatgctg gagttcttcg cccaccccaa
3960cttgtttatt gcagcttata atggttacaa ataaagcaat agcatcacaa
atttcacaaa 4020taaagcattt ttttcactgc attctagttg tggtttgtcc
aaactcatca atgtatctta 4080tcatgtctgt ataccgtcga cctctagcta
gagcttggcg taatcatggt catagctgtt 4140tcctgtgtga aattgttatc
cgctcacaat tccacacaac atacgagccg gaagcataaa 4200gtgtaaagcc
tggggtgcct aatgagtgag ctaactcaca ttaattgcgt tgcgctcact
4260gcccgctttc cagtcgggaa acctgtcgtg ccagctgcat taatgaatcg
gccaacgcgc 4320ggggagaggc ggtttgcgta ttgggcgctc ttccgcttcc
tcgctcactg actcgctgcg 4380ctcggtcgtt cggctgcggc gagcggtatc
agctcactca aaggcggtaa tacggttatc 4440cacagaatca ggggataacg
caggaaagaa catgtgagca aaaggccagc aaaaggccag 4500gaaccgtaaa
aaggccgcgt tgctggcgtt tttccatagg ctccgccccc ctgacgagca
4560tcacaaaaat cgacgctcaa gtcagaggtg gcgaaacccg acaggactat
aaagatacca 4620ggcgtttccc cctggaagct ccctcgtgcg ctctcctgtt
ccgaccctgc cgcttaccgg 4680atacctgtcc gcctttctcc cttcgggaag
cgtggcgctt tctcatagct cacgctgtag 4740gtatctcagt tcggtgtagg
tcgttcgctc caagctgggc tgtgtgcacg aaccccccgt 4800tcagcccgac
cgctgcgcct tatccggtaa ctatcgtctt gagtccaacc cggtaagaca
4860cgacttatcg ccactggcag cagccactgg taacaggatt agcagagcga
ggtatgtagg 4920cggtgctaca gagttcttga agtggtggcc taactacggc
tacactagaa gaacagtatt 4980tggtatctgc gctctgctga agccagttac
cttcggaaaa agagttggta gctcttgatc 5040cggcaaacaa accaccgctg
gtagcggttt ttttgtttgc aagcagcaga ttacgcgcag 5100aaaaaaagga
tctcaagaag atcctttgat cttttctacg gggtctgacg ctcagtggaa
5160cgaaaactca cgttaaggga ttttggtcat gagattatca aaaaggatct
tcacctagat 5220ccttttaaat taaaaatgaa gttttaaatc aatctaaagt
atatatgagt aaacttggtc 5280tgacagttac caatgcttaa tcagtgaggc
acctatctca gcgatctgtc tatttcgttc 5340atccatagtt gcctgactcc
ccgtcgtgta gataactacg atacgggagg gcttaccatc 5400tggccccagt
gctgcaatga taccgcgaga cccacgctca ccggctccag atttatcagc
5460aataaaccag ccagccggaa gggccgagcg cagaagtggt cctgcaactt
tatccgcctc 5520catccagtct attaattgtt gccgggaagc tagagtaagt
agttcgccag ttaatagttt 5580gcgcaacgtt gttgccattg ctacaggcat
cgtggtgtca cgctcgtcgt ttggtatggc 5640ttcattcagc tccggttccc
aacgatcaag gcgagttaca tgatccccca tgttgtgcaa 5700aaaagcggtt
agctccttcg gtcctccgat cgttgtcaga agtaagttgg ccgcagtgtt
5760atcactcatg gttatggcag cactgcataa ttctcttact gtcatgccat
ccgtaagatg 5820cttttctgtg actggtgagt actcaaccaa gtcattctga
gaatagtgta tgcggcgacc 5880gagttgctct tgcccggcgt caatacggga
taataccgcg ccacatagca gaactttaaa 5940agtgctcatc attggaaaac
gttcttcggg gcgaaaactc tcaaggatct taccgctgtt 6000gagatccagt
tcgatgtaac ccactcgtgc acccaactga tcttcagcat cttttacttt
6060caccagcgtt tctgggtgag caaaaacagg aaggcaaaat gccgcaaaaa
agggaataag 6120ggcgacacgg aaatgttgaa tactcatact cttccttttt
caatattatt gaagcattta 6180tcagggttat tgtctcatga gcggatacat
atttgaatgt atttagaaaa ataaacaaat 6240aggggttccg cgcacatttc
cccgaaaagt gccacctgac gtc 62832796267DNAArtificial sequenceVector
pSyn-C05-Ckappa 279gacggatcgg gagatctccc gatcccctat ggtgcactct
cagtacaatc tgctctgatg 60ccgcatagtt aagccagtat ctgctccctg cttgtgtgtt
ggaggtcgct gagtagtgcg 120cgagcaaaat ttaagctaca acaaggcaag
gcttgaccga caattgttaa ttaacatgaa 180gaatctgctt agggttaggc
gttttgcgct gcttcgctag gtggtcaata ttggccatta 240gccatattat
tcattggtta tatagcataa atcaatattg gctattggcc attgcatacg
300ttgtatccat atcataatat gtacatttat attggctcat gtccaacatt
accgccatgt 360tgacattgat tattgactag ttattaatag taatcaatta
cggggtcatt agttcatagc 420ccatatatgg agttccgcgt tacataactt
acggtaaatg gcccgcctgg ctgaccgccc 480aacgaccccc gcccattgac
gtcaataatg acgtatgttc ccatagtaac gccaataggg 540actttccatt
gacgtcaatg ggtggagtat ttacggtaaa ctgcccactt ggcagtacat
600caagtgtatc atatgccaag tacgccccct attgacgtca atgacggtaa
atggcccgcc 660tggcattatg
cccagtacat gaccttatgg gactttccta cttggcagta catctacgta
720ttagtcatcg ctattaccat ggtgatgcgg ttttggcagt acatcaatgg
gcgtggatag 780cggtttgact cacggggatt tccaagtctc caccccattg
acgtcaatgg gagtttgttt 840tggcaccaaa atcaacggga ctttccaaaa
tgtcgtaaca actccgcccc attgacgcaa 900atgggcggta ggcgtgtacg
gtgggaggtc tatataagca gagctcgttt agtgaaccgt 960cagatcgcct
ggagacgcca tccacgctgt tttgacctcc atagaagaca ccgggaccga
1020tccagcctcc gcggccggga acggtgcatt ggaatcgatg actctcttag
gtagccttgc 1080agaagttggt cgtgaggcac tgggcaggta agtatcaagg
ttacaagaca ggtttaagga 1140gatcaataga aactgggctt gtcgagacag
agaagactct tgcgtttctg ataggcacct 1200attggtctta ctgacatcca
ctttgccttt ctctccacag gtgtccactc ccagttcaat 1260tacagctcgc
caccatggcc tgccccggct tcctgtgggc cctggtgatc agcacctgcc
1320tcgagttcag cggccctaag cggaccgtgg ccgctcccag cgtgttcatc
ttccccccct 1380ccgacgagca gctgaagagc ggcaccgcca gcgtggtgtg
cctgctgaac aacttctacc 1440cccgggaggc caaggtgcag tggaaggtgg
acaacgccct gcagagcggc aacagccagg 1500agagcgtgac cgagcaggac
agcaaggact ccacctacag cctgagcagc accctcaccc 1560tgagcaaggc
cgactacgag aagcacaagg tgtacgcctg cgaggtgacc caccagggcc
1620tgagcagccc cgtgaccaag agcttcaacc ggggcgagtg ttaatagact
taagtttaaa 1680ccgctgatca gcctcgactg tgccttctag ttgccagcca
tctgttgttt gcccctcccc 1740cgtgccttcc ttgaccctgg aaggtgccac
tcccactgtc ctttcctaat aaaatgagga 1800aattgcatcg cattgtctga
gtaggtgtca ttctattctg gggggtgggg tggggcagga 1860cagcaagggg
gaggattggg aagacaatag caggcatgct ggggatgcgg tgggctctat
1920ggcttctgag gcggaaagaa ccagctgggg ctctaggggg tatccccacg
cgccctgtag 1980cggcgcatta agcgcggcgg gtgtggtggt tacgcgcagc
gtgaccgcta cacttgccag 2040cgccctagcg cccgctcctt tcgctttctt
cccttccttt ctcgccacgt tcgccggctt 2100tccccgtcaa gctctaaatc
gggggctccc tttagggttc cgatttagtg ctttacggca 2160cctcgacccc
aaaaaacttg attagggtga tggttcacgt agtgggccat cgccctgata
2220gacggttttt cgccctttga cgttggagtc cacgttcttt aatagtggac
tcttgttcca 2280aactggaaca acactcaacc ctatctcggt ctattctttt
gatttataag ggattttggc 2340catttcggcc tattggttaa aaaatgagct
gatttaacaa aaatttaacg cgaattaatt 2400ctgtggaatg tgtgtcagtt
agggtgtgga aagtccccag gctccccagc aggcagaagt 2460atgcaaagca
tgcatctcaa ttagtcagca accaggtgtg gaaagtcccc aggctcccca
2520gcaggcagaa gtatgcaaag catgcatctc aattagtcag caaccatagt
cccgccccta 2580actccgccca tcccgcccct aactccgccc agttccgccc
attctccgcc ccatggctga 2640ctaatttttt ttatttatgc agaggccgag
gccgcctctg cctctgagct attccagaag 2700tagtgaggag gcttttttgg
aggcctaggc ttttgcaaaa agctcccggg agcttgtata 2760tccattttcg
gatctgatca gcacgtgatg aaaaagcctg aactcaccgc gacgtctgtc
2820gagaagtttc tgatcgaaaa gttcgacagc gtctccgacc tgatgcagct
ctcggagggc 2880gaagaatctc gtgctttcag cttcgatgta ggagggcgtg
gatatgtcct gcgggtaaat 2940agctgcgccg atggtttcta caaagatcgt
tatgtttatc ggcactttgc atcggccgcg 3000ctcccgattc cggaagtgct
tgacattggg gaattcagcg agagcctgac ctattgcatc 3060tcccgccgtg
cacagggtgt cacgttgcaa gacctgcctg aaaccgaact gcccgctgtt
3120ctgcagccgg tcgcggaggc catggatgcg atcgctgcgg ccgatcttag
ccagacgagc 3180gggttcggcc cattcggacc acaaggaatc ggtcaataca
ctacatggcg tgatttcata 3240tgcgcgattg ctgatcccca tgtgtatcac
tggcaaactg tgatggacga caccgtcagt 3300gcgtccgtcg cgcaggctct
cgatgagctg atgctttggg ccgaggactg ccccgaagtc 3360cggcacctcg
tgcacgcgga tttcggctcc aacaatgtcc tgacggacaa tggccgcata
3420acagcggtca ttgactggag cgaggcgatg ttcggggatt cccaatacga
ggtcgccaac 3480atcttcttct ggaggccgtg gttggcttgt atggagcagc
agacgcgcta cttcgagcgg 3540aggcatccgg agcttgcagg atcgccgcgg
ctccgggcgt atatgctccg cattggtctt 3600gaccaactct atcagagctt
ggttgacggc aatttcgatg atgcagcttg ggcgcagggt 3660cgatgcgacg
caatcgtccg atccggagcc gggactgtcg ggcgtacaca aatcgcccgc
3720agaagcgcgg ccgtctggac cgatggctgt gtagaagtac tcgccgatag
tggaaaccga 3780cgccccagca ctcgtccgag ggcaaaggaa tagcacgtgc
tacgagattt cgattccacc 3840gccgccttct atgaaaggtt gggcttcgga
atcgttttcc gggacgccgg ctggatgatc 3900ctccagcgcg gggatctcat
gctggagttc ttcgcccacc ccaacttgtt tattgcagct 3960tataatggtt
acaaataaag caatagcatc acaaatttca caaataaagc atttttttca
4020ctgcattcta gttgtggttt gtccaaactc atcaatgtat cttatcatgt
ctgtataccg 4080tcgacctcta gctagagctt ggcgtaatca tggtcatagc
tgtttcctgt gtgaaattgt 4140tatccgctca caattccaca caacatacga
gccggaagca taaagtgtaa agcctggggt 4200gcctaatgag tgagctaact
cacattaatt gcgttgcgct cactgcccgc tttccagtcg 4260ggaaacctgt
cgtgccagct gcattaatga atcggccaac gcgcggggag aggcggtttg
4320cgtattgggc gctcttccgc ttcctcgctc actgactcgc tgcgctcggt
cgttcggctg 4380cggcgagcgg tatcagctca ctcaaaggcg gtaatacggt
tatccacaga atcaggggat 4440aacgcaggaa agaacatgtg agcaaaaggc
cagcaaaagg ccaggaaccg taaaaaggcc 4500gcgttgctgg cgtttttcca
taggctccgc ccccctgacg agcatcacaa aaatcgacgc 4560tcaagtcaga
ggtggcgaaa cccgacagga ctataaagat accaggcgtt tccccctgga
4620agctccctcg tgcgctctcc tgttccgacc ctgccgctta ccggatacct
gtccgccttt 4680ctcccttcgg gaagcgtggc gctttctcat agctcacgct
gtaggtatct cagttcggtg 4740taggtcgttc gctccaagct gggctgtgtg
cacgaacccc ccgttcagcc cgaccgctgc 4800gccttatccg gtaactatcg
tcttgagtcc aacccggtaa gacacgactt atcgccactg 4860gcagcagcca
ctggtaacag gattagcaga gcgaggtatg taggcggtgc tacagagttc
4920ttgaagtggt ggcctaacta cggctacact agaagaacag tatttggtat
ctgcgctctg 4980ctgaagccag ttaccttcgg aaaaagagtt ggtagctctt
gatccggcaa acaaaccacc 5040gctggtagcg gtttttttgt ttgcaagcag
cagattacgc gcagaaaaaa aggatctcaa 5100gaagatcctt tgatcttttc
tacggggtct gacgctcagt ggaacgaaaa ctcacgttaa 5160gggattttgg
tcatgagatt atcaaaaagg atcttcacct agatcctttt aaattaaaaa
5220tgaagtttta aatcaatcta aagtatatat gagtaaactt ggtctgacag
ttaccaatgc 5280ttaatcagtg aggcacctat ctcagcgatc tgtctatttc
gttcatccat agttgcctga 5340ctccccgtcg tgtagataac tacgatacgg
gagggcttac catctggccc cagtgctgca 5400atgataccgc gagacccacg
ctcaccggct ccagatttat cagcaataaa ccagccagcc 5460ggaagggccg
agcgcagaag tggtcctgca actttatccg cctccatcca gtctattaat
5520tgttgccggg aagctagagt aagtagttcg ccagttaata gtttgcgcaa
cgttgttgcc 5580attgctacag gcatcgtggt gtcacgctcg tcgtttggta
tggcttcatt cagctccggt 5640tcccaacgat caaggcgagt tacatgatcc
cccatgttgt gcaaaaaagc ggttagctcc 5700ttcggtcctc cgatcgttgt
cagaagtaag ttggccgcag tgttatcact catggttatg 5760gcagcactgc
ataattctct tactgtcatg ccatccgtaa gatgcttttc tgtgactggt
5820gagtactcaa ccaagtcatt ctgagaatag tgtatgcggc gaccgagttg
ctcttgcccg 5880gcgtcaatac gggataatac cgcgccacat agcagaactt
taaaagtgct catcattgga 5940aaacgttctt cggggcgaaa actctcaagg
atcttaccgc tgttgagatc cagttcgatg 6000taacccactc gtgcacccaa
ctgatcttca gcatctttta ctttcaccag cgtttctggg 6060tgagcaaaaa
caggaaggca aaatgccgca aaaaagggaa taagggcgac acggaaatgt
6120tgaatactca tactcttcct ttttcaatat tattgaagca tttatcaggg
ttattgtctc 6180atgagcggat acatatttga atgtatttag aaaaataaac
aaataggggt tccgcgcaca 6240tttccccgaa aagtgccacc tgacgtc
626728046DNAArtificial sequenceOligonucleotide 5H-B 280acctgtcttg
aattctccat ggccgaggtg cagctggtgg agtctg 4628147DNAArtificial
sequenceOligonucleotide 5H-C 281acctgtcttg aattctccat ggcccaggtg
cagctggtgg agtctgg 4728249DNAArtificial sequenceOligonucleotide
5H-C-long 282acctgtcttg aattctccat ggcccaggtg cagctggtgg agtctgggg
4928350DNAArtificial sequenceOligonucleotide 5H-F 283acctgtcttg
aattctccat ggcccaggtg cagctgcagg agtccggccc 5028447DNAArtificial
sequenceOligonucleotide 5H-H 284acctgtcttg aattctccat ggccgaggtg
cagctggtgc agtctgg 4728547DNAArtificial sequenceOligonucleotide
5H-I 285acctgtcttg aattctccat ggccgaggtg cagctgctgg agtctgg
4728647DNAArtificial sequenceOligonucleotide 5H-M 286acctgtcttg
aattctccat ggcccaggtg accttgaagg agtctgg 4728747DNAArtificial
sequenceOligonucleotide sy3H-A 287gcccttggtg ctagcgctgg agacggtcac
cagggtgccc tggcccc 4728847DNAArtificial sequenceOligonucleotide
sy3H-C 288gcccttggtg ctagcgctgg agacggtcac ggtggtgccc tggcccc
4728954DNAArtificial sequenceOligonucleotide sy3H-C-long
289gcccttggtg ctagcgctgg agacggtcac ggtggtgccc ttgccccaga cgtc
5429047DNAArtificial sequenceOligonucleotide sy3H-D 290gcccttggtg
ctagcgctgg acacggtcac catggtgccc tggcccc 4729147DNAArtificial
sequenceOligonucleotide sy3H-E 291gcccttggtg ctagcgctgg acacggtcac
cagggtgccc cggcccc 4729244DNAArtificial sequenceOligonucleotide
3L-B 292ttttccttag cggccgcgac tcacctagga cggtcagctt ggtc
4429344DNAArtificial sequenceOligonucleotide 5K-B 293acctgtctcg
agttttccat ggctgacatc cagatgaccc agtc 4429455DNAArtificial
sequenceOligonucleotide 5K-C 294acctgtctcg agttttccat ggctgacatc
cagatgaccc agtctccatc ctccc 5529547DNAArtificial
sequenceOligonucleotide 5K-G 295acctgtctcg agttttccat ggctgacatc
gtgatgaccc agtctcc 4729647DNAArtificial sequenceOligonucleotide
5K-K 296acctgtctcg agttttccat ggctgccatc cagatgaccc agtctcc
4729744DNAArtificial sequenceOligonucleotide 5K-M 297acctgtctcg
agttttccat ggctgacatc cagctgaccc agtc 4429844DNAArtificial
sequenceOligonucleotide 5K-N 298acctgtctcg agttttccat ggctgacatc
cagatgactc agtc 4429944DNAArtificial sequenceOligonucleotide 5K-O
299acctgtctcg agttttccat ggctgccatc cagctgaccc agtc
4430044DNAArtificial sequenceOligonucleotide 5K-Q 300acctgtctcg
agttttccat ggctgagatc gtgatgactc agtc 4430145DNAArtificial
sequenceOligonucleotide 5L-E 301acctgtctcg agttttccat ggcttcctac
gtgctgactc agccg 4530244DNAArtificial sequenceOligonucleotide 5L-F
302acctgtctcg agttttccat ggctcagtcc gtgctgactc agcc
4430344DNAArtificial sequenceOligoucleotide 5L-G 303acctgtctcg
agttttccat ggcttcctac gtgctgactc agcc 4430442DNAArtificial
sequenceOligonucleotide sy3K-F 304gctgggggcg gccacggtcc gcttgatctc
caccttggtc cc 4230542DNAArtificial sequenceOligonucleotide sy3K-I
305gctgggggcg gccacggtcc gcttgatctc cagccgtgtc cc
4230642DNAArtificial sequenceOligonucleotide sy3K-J 306gctgggggcg
gccacggtcc gcttgatctc cagcttggtc cc 4230742DNAArtificial
sequenceOligonucleotide sy3K-K 307gctgggggcg gccacggtcc gcttgatgtc
caccttggtc cc 4230843DNAArtificial sequenceOligonucleotide sy3L-A
308ccagcacggt aagcttcagc acggtcacct tggtgccagt tcc
4330943DNAArtificial sequenceOligonucleotide sy3L-C 309ccagcacggt
aagcttcagc acggtcagct tggtgcctcc gcc 4331037DNAArtificial
sequenceOligonucleotide sy3L-D 310ccagcacggt aagcttcaac acggtcagct
gggtccc 3731152DNAArtificial sequenceOligonucleotide sy5L-A
311acctgtctcg agttttccat ggcttcctcc gagctgaccc aggaccctgc tg
52312756DNAArtificial sequencescFv SOJB 312gccatggccc agatcaccct
gaaggagacc ggccccaccc tggtgaagcc cacccagacc 60ctcaccctca cctgcacctt
cagcggcttc agcctgagca ccagcggcgt gggcgtgggc 120tggatcagac
agccccctgg caaggccctg gagtgggtga ccctcatcta ctgggacgac
180gacaagagat acagccccag cctggagaac agggtgacca tccggaagga
caccagcaag 240aaccaggtgg ccctcaccat gaccaacatg gaccccctgg
ataccggcac ctactactgc 300gcccacaggc agcacatcag cagcttcccc
tggttcgaca gctggggcca gggcacactg 360gtgaccgtct cgagcggtac
gggcggttca ggcggaaccg gcagcggcac tggcgggtcg 420acgagctacg
tgctcaccca gccccccagc gtgagcgtgg cccctggcaa gaccgccaga
480atcaactgcg gcggcaacaa catcgagtac cggagcgtgc actggtatca
gcagaagagc 540ggccaggccc ccgtggccgt gatctacgac aacagcgaca
gacctagcgg catccccgag 600agattcagcg gcagcaagag cggcaacacc
gccaccctca ccatcagcag agtggaggcc 660ggcgacgagg ccgactacta
ctgccaggtg tgggacatca gcagcgatgt ggtgttcggc 720ggaggcacca
agcttaccgt gctaggtgcg gccgca 756313252PRTArtificial sequencescFv
SOJB 313Ala Met Ala Gln Ile Thr Leu Lys Glu Thr Gly Pro Thr Leu Val
Lys1 5 10 15Pro Thr Gln Thr Leu Thr Leu Thr Cys Thr Phe Ser Gly Phe
Ser Leu 20 25 30Ser Thr Ser Gly Val Gly Val Gly Trp Ile Arg Gln Pro
Pro Gly Lys 35 40 45Ala Leu Glu Trp Val Thr Leu Ile Tyr Trp Asp Asp
Asp Lys Arg Tyr 50 55 60Ser Pro Ser Leu Glu Asn Arg Val Thr Ile Arg
Lys Asp Thr Ser Lys65 70 75 80Asn Gln Val Ala Leu Thr Met Thr Asn
Met Asp Pro Leu Asp Thr Gly 85 90 95Thr Tyr Tyr Cys Ala His Arg Gln
His Ile Ser Ser Phe Pro Trp Phe 100 105 110Asp Ser Trp Gly Gln Gly
Thr Leu Val Thr Val Ser Ser Gly Thr Gly 115 120 125Gly Ser Gly Gly
Thr Gly Ser Gly Thr Gly Gly Ser Thr Ser Tyr Val 130 135 140Leu Thr
Gln Pro Pro Ser Val Ser Val Ala Pro Gly Lys Thr Ala Arg145 150 155
160Ile Asn Cys Gly Gly Asn Asn Ile Glu Tyr Arg Ser Val His Trp Tyr
165 170 175Gln Gln Lys Ser Gly Gln Ala Pro Val Ala Val Ile Tyr Asp
Asn Ser 180 185 190Asp Arg Pro Ser Gly Ile Pro Glu Arg Phe Ser Gly
Ser Lys Ser Gly 195 200 205Asn Thr Ala Thr Leu Thr Ile Ser Arg Val
Glu Ala Gly Asp Glu Ala 210 215 220Asp Tyr Tyr Cys Gln Val Trp Asp
Ile Ser Ser Asp Val Val Phe Gly225 230 235 240Gly Gly Thr Lys Leu
Thr Val Leu Gly Ala Ala Ala 245 25031415PRTArtificial
sequencePeptide 314Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys Gly
Val Leu Gly1 5 10 1531515PRTArtificial sequencePeptide 315Leu Lys
Gly Ala Cys Lys Leu Lys Leu Cys Gly Val Leu Gly Leu1 5 10
1531615PRTArtificial sequencePeptide 316Lys Gly Ala Cys Lys Leu Lys
Leu Cys Gly Val Leu Gly Leu Arg1 5 10 1531715PRTArtificial
sequencePeptide 317Gly Ala Cys Lys Leu Lys Leu Cys Gly Val Leu Gly
Leu Arg Leu1 5 10 1531815PRTArtificial sequencePeptide 318Ala Cys
Lys Leu Lys Leu Cys Gly Val Leu Gly Leu Arg Leu Met1 5 10
1531915PRTArtificial sequencePeptide 319Cys Lys Leu Lys Leu Cys Gly
Val Leu Gly Leu Arg Leu Met Asp1 5 10 1532015PRTArtificial
sequencePeptide 320Lys Leu Lys Leu Cys Gly Val Leu Gly Leu Arg Leu
Met Asp Gly1 5 10 1532115PRTArtificial sequencePeptide 321Leu Lys
Leu Cys Gly Val Leu Gly Leu Arg Leu Met Asp Gly Thr1 5 10
1532215PRTArtificial sequencePeptide 322Lys Leu Cys Gly Val Leu Gly
Leu Arg Leu Met Asp Gly Thr Trp1 5 10 1532315PRTArtificial
sequencePeptide 323Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn Lys Thr
Leu Met Glu1 5 10 1532415PRTArtificial sequencePeptide 324Phe Gly
Lys Ala Tyr Thr Ile Phe Asn Lys Thr Leu Met Glu Ala1 5 10
1532515PRTArtificial sequencePeptide 325Gly Lys Ala Tyr Thr Ile Phe
Asn Lys Thr Leu Met Glu Ala Asp1 5 10 1532615PRTArtificial
sequencePeptide 326Lys Ala Tyr Thr Ile Phe Asn Lys Thr Leu Met Glu
Ala Asp Ala1 5 10 1532715PRTArtificial sequencePeptide 327Ala Tyr
Thr Ile Phe Asn Lys Thr Leu Met Glu Ala Asp Ala His1 5 10
1532815PRTArtificial sequencePeptide 328Tyr Thr Ile Phe Asn Lys Thr
Leu Met Glu Ala Asp Ala His Tyr1 5 10 1532915PRTArtificial
sequencePeptide 329Thr Ile Phe Asn Lys Thr Leu Met Glu Ala Asp Ala
His Tyr Lys1 5 10 1533015PRTArtificial sequencePeptide 330Ile Phe
Asn Lys Thr Leu Met Glu Ala Asp Ala His Tyr Lys Ser1 5 10
1533115PRTArtificial sequencePeptide 331Phe Asn Lys Thr Leu Met Glu
Ala Asp Ala His Tyr Lys Ser Val1 5 10 1533223PRTArtificial
sequencePeptide 332Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys Gly
Val Leu Gly Leu1 5 10 15Arg Leu Met Asp Gly Thr Trp
2033323PRTArtificial sequencePeptide 333Gly Phe Gly Lys Ala Tyr Thr
Ile Phe Asn Lys Thr Leu Met Glu Ala1 5 10 15Asp Ala His Tyr Lys Ser
Val 203342083DNAArtificial sequenceHeavy chain of CR04-098
334caggtgcagc tggtggagtc tgggggaggc gcggtccagc ctgggaggtc
cctgagactc 60tcctgtgcag cctctggatt caccttcagt agctatggca tgcactgggt
ccgccaggct 120ccaggcaagg ggctggagtg ggtggctgtt atattatatg
atggaagtga taaattctat 180gcagactccg tgaagggccg attcaccatc
tccagagaca attccaagaa cacgctgtat 240ctgcagatga acagcctgag
agctgaggac acggctgtgt attactgtgc gaaagtagca 300gtggctggta
cgcactttga ctactggggc cagggcaccc tggtgaccgt cagctcaggt
360gagtgcggcc gcgagcccag acactggacg ctgaacctcg cggacagtta
agaacccagg 420ggcctctgcg ccctgggccc agctctgtcc cacaccgcgg
tcacatggca ccacctctct 480tgcagcctcc
accaagggcc catcggtctt ccccctggca ccctcctcca agagcacctc
540tgggggcaca gcggccctgg gctgcctggt caaggactac ttccccgaac
cggtgacggt 600gtcgtggaac tcaggcgccc tgaccagcgg cgtgcacacc
ttcccggctg tcctacagtc 660ctcaggactc tactccctca gcagcgtggt
gaccgtgccc tccagcagct tgggcaccca 720gacctacatc tgcaacgtga
atcacaagcc cagcaacacc aaggtggaca agagagttgg 780tgagaggcca
gcacagggag ggagggtgtc tgctggaagc caggctcagc gctcctgcct
840ggacgcatcc cggctatgca gtcccagtcc agggcagcaa ggcaggcccc
gtctgcctct 900tcacccggag gcctctgccc gccccactca tgctcaggga
gagggtcttc tggctttttc 960cccaggctct gggcaggcac aggctaggtg
cccctaaccc aggccctgca cacaaagggg 1020caggtgctgg gctcagacct
gccaagagcc atatccggga ggaccctgcc cctgacctaa 1080gcccacccca
aaggccaaac tctccactcc ctcagctcgg acaccttctc tcctcccaga
1140ttccagtaac tcccaatctt ctctctgcag agcccaaatc ttgtgacaaa
actcacacat 1200gcccaccgtg cccaggtaag ccagcccagg cctcgccctc
cagctcaagg cgggacaggt 1260gccctagagt agcctgcatc cagggacagg
ccccagccgg gtgctgacac gtccacctcc 1320atctcttcct cagcacctga
actcctgggg ggaccgtcag tcttcctctt ccccccaaaa 1380cccaaggaca
ccctcatgat ctcccggacc cctgaggtca catgcgtggt ggtggacgtg
1440agccacgaag accctgaggt caagttcaac tggtacgtgg acggcgtgga
ggtgcataat 1500gccaagacaa agccgcggga ggagcagtac aacagcacgt
accgtgtggt cagcgtcctc 1560accgtcctgc accaggactg gctgaatggc
aaggagtaca agtgcaaggt ctccaacaaa 1620gccctcccag cccccatcga
gaaaaccatc tccaaagcca aaggtgggac ccgtggggtg 1680cgagggccac
atggacagag gccggctcgg cccaccctct gccctgagag tgaccgctgt
1740accaacctct gtccctacag ggcagccccg agaaccacag gtgtacaccc
tgcccccatc 1800ccgggaggag atgaccaaga accaggtcag cctgacctgc
ctggtcaaag gcttctatcc 1860cagcgacatc gccgtggagt gggagagcaa
tgggcagccg gagaacaact acaagaccac 1920gcctcccgtg ctggactccg
acggctcctt cttcctctat agcaagctca ccgtggacaa 1980gagcaggtgg
cagcagggga acgtcttctc atgctccgtg atgcatgagg ctctgcacaa
2040ccactacacg cagaagagcc tctccctgtc tccgggtaaa tga
2083335449PRTArtificial sequenceHeavy chain of CR04-098 335Gln Val
Gln Leu Val Glu Ser Gly Gly Gly Ala Val Gln Pro Gly Arg1 5 10 15Ser
Leu Arg Leu Ser Cys Ala Ala Ser Gly Phe Thr Phe Ser Ser Tyr 20 25
30Gly Met His Trp Val Arg Gln Ala Pro Gly Lys Gly Leu Glu Trp Val
35 40 45Ala Val Ile Leu Tyr Asp Gly Ser Asp Lys Phe Tyr Ala Asp Ser
Val 50 55 60Lys Gly Arg Phe Thr Ile Ser Arg Asp Asn Ser Lys Asn Thr
Leu Tyr65 70 75 80Leu Gln Met Asn Ser Leu Arg Ala Glu Asp Thr Ala
Val Tyr Tyr Cys 85 90 95Ala Lys Val Ala Val Ala Gly Thr His Phe Asp
Tyr Trp Gly Gln Gly 100 105 110Thr Leu Val Thr Val Ser Ser Ala Ser
Thr Lys Gly Pro Ser Val Phe 115 120 125Pro Leu Ala Pro Ser Ser Lys
Ser Thr Ser Gly Gly Thr Ala Ala Leu 130 135 140Gly Cys Leu Val Lys
Asp Tyr Phe Pro Glu Pro Val Thr Val Ser Trp145 150 155 160Asn Ser
Gly Ala Leu Thr Ser Gly Val His Thr Phe Pro Ala Val Leu 165 170
175Gln Ser Ser Gly Leu Tyr Ser Leu Ser Ser Val Val Thr Val Pro Ser
180 185 190Ser Ser Leu Gly Thr Gln Thr Tyr Ile Cys Asn Val Asn His
Lys Pro 195 200 205Ser Asn Thr Lys Val Asp Lys Arg Val Glu Pro Lys
Ser Cys Asp Lys 210 215 220Thr His Thr Cys Pro Pro Cys Pro Ala Pro
Glu Leu Leu Gly Gly Pro225 230 235 240Ser Val Phe Leu Phe Pro Pro
Lys Pro Lys Asp Thr Leu Met Ile Ser 245 250 255Arg Thr Pro Glu Val
Thr Cys Val Val Val Asp Val Ser His Glu Asp 260 265 270Pro Glu Val
Lys Phe Asn Trp Tyr Val Asp Gly Val Glu Val His Asn 275 280 285Ala
Lys Thr Lys Pro Arg Glu Glu Gln Tyr Asn Ser Thr Tyr Arg Val 290 295
300Val Ser Val Leu Thr Val Leu His Gln Asp Trp Leu Asn Gly Lys
Glu305 310 315 320Tyr Lys Cys Lys Val Ser Asn Lys Ala Leu Pro Ala
Pro Ile Glu Lys 325 330 335Thr Ile Ser Lys Ala Lys Gly Gln Pro Arg
Glu Pro Gln Val Tyr Thr 340 345 350Leu Pro Pro Ser Arg Glu Glu Met
Thr Lys Asn Gln Val Ser Leu Thr 355 360 365Cys Leu Val Lys Gly Phe
Tyr Pro Ser Asp Ile Ala Val Glu Trp Glu 370 375 380Ser Asn Gly Gln
Pro Glu Asn Asn Tyr Lys Thr Thr Pro Pro Val Leu385 390 395 400Asp
Ser Asp Gly Ser Phe Phe Leu Tyr Ser Lys Leu Thr Val Asp Lys 405 410
415Ser Arg Trp Gln Gln Gly Asn Val Phe Ser Cys Ser Val Met His Glu
420 425 430Ala Leu His Asn His Tyr Thr Gln Lys Ser Leu Ser Leu Ser
Pro Gly 435 440 445Lys 336847DNAArtificial sequenceLight chain of
CR04-098 336gacatccaga tgacccagtc tccatcctcc ctgtctgcat ctgtaggaga
cagagtcacc 60atcacttgcc gggcaagtca gggcattaga aatgatttag gctggtatca
gcagaaacca 120gggaaagccc ctaagctcct gatctatgct gcatccagtt
tgcaaagtgg ggtcccatca 180aggttcagcg gcagtggatc tgggacagat
ttcactctca ccatcagcag cctgcagcct 240gaagattttg caacttatta
ctgtcaacag cttaatagtt accctcccac tttcggcgga 300gggaccaagg
tggagatcaa acgtaagtgc actttgcggc cgctaggaag aaactcaaaa
360catcaagatt ttaaatacgc ttcttggtct ccttgctata attatctggg
ataagcatgc 420tgttttctgt ctgtccctaa catgccctgt gattatccgc
aaacaacaca cccaagggca 480gaactttgtt acttaaacac catcctgttt
gcttctttcc tcaggaactg tggctgcacc 540atctgtcttc atcttcccgc
catctgatga gcagttgaaa tctggaactg cctctgttgt 600gtgcctgctg
aataacttct atcccagaga ggccaaagta cagtggaagg tggataacgc
660cctccaatcg ggtaactccc aggagagtgt cacagagcag gacagcaagg
acagcaccta 720cagcctcagc agcaccctga cgctgagcaa agcagactac
gagaaacaca aagtctacgc 780ctgcgaagtc acccatcagg gcctgagctc
gcccgtcaca aagagcttca acaggggaga 840gtgttag 847337213PRTArtificial
sequenceLight chain of CR04-098 337Asp Ile Gln Met Thr Gln Ser Pro
Ser Ser Leu Ser Ala Ser Val Gly1 5 10 15Asp Arg Val Thr Ile Thr Cys
Arg Ala Ser Gln Gly Ile Arg Asn Asp 20 25 30Leu Gly Trp Tyr Gln Gln
Lys Pro Gly Lys Ala Pro Lys Leu Leu Ile 35 40 45Tyr Ala Ala Ser Ser
Leu Gln Ser Gly Val Pro Ser Arg Phe Ser Gly 50 55 60Ser Gly Ser Gly
Thr Asp Phe Thr Leu Thr Ile Ser Ser Leu Gln Pro65 70 75 80Glu Asp
Phe Ala Thr Tyr Tyr Cys Gln Gln Leu Asn Ser Tyr Pro Pro 85 90 95Thr
Phe Gly Gly Gly Thr Lys Val Glu Ile Lys Thr Val Ala Ala Pro 100 105
110Ser Val Phe Ile Phe Pro Pro Ser Asp Glu Gln Leu Lys Ser Gly Thr
115 120 125Ala Ser Val Val Cys Leu Leu Asn Asn Phe Tyr Pro Arg Glu
Ala Lys 130 135 140Val Gln Trp Lys Val Asp Asn Ala Leu Gln Ser Gly
Asn Ser Gln Glu145 150 155 160Ser Val Thr Glu Gln Asp Ser Lys Asp
Ser Thr Tyr Ser Leu Ser Ser 165 170 175Thr Leu Thr Leu Ser Lys Ala
Asp Tyr Glu Lys His Lys Val Tyr Ala 180 185 190Cys Glu Val Thr His
Gln Gly Leu Ser Ser Pro Val Thr Lys Ser Phe 195 200 205Asn Arg Gly
Glu Cys 21033815PRTArtificial Sequence15 contiguous and consecutive
amino acids from the extracellular domain of glycoprotein G of
rabies virus strain ERA (SEQ ID NO207), wherein the extracellular
domain of glycoprotein G consists of amino acids 20-458 of SEQ ID
NO207. 338Lys Phe Pro Ile Tyr Thr Ile Leu Asp Lys Leu Gly Pro Trp
Ser1 5 10 1533915PRTArtificial Sequence15 contiguous and
consecutive amino acids from the extracellular domain of
glycoprotein G of rabies virus strain ERA (SEQ ID NO207), wherein
the extracellular domain of glycoprotein G consists of amino acids
20-458 of SEQ ID NO207. 339Phe Pro Ile Tyr Thr Ile Leu Asp Lys Leu
Gly Pro Trp Ser Pro1 5 10 1534015PRTArtificial Sequence15
contiguous and consecutive amino acids from the extracellular
domain of glycoprotein G of rabies virus strain ERA (SEQ ID NO207),
wherein the extracellular domain of glycoprotein G consists of
amino acids 20-458 of SEQ ID NO207. 340Pro Ile Tyr Thr Ile Leu Asp
Lys Leu Gly Pro Trp Ser Pro Ile1 5 10 1534115PRTArtificial
Sequence15 contiguous and consecutive amino acids from the
extracellular domain of glycoprotein G of rabies virus strain ERA
(SEQ ID NO207), wherein the extracellular domain of glycoprotein G
consists of amino acids 20-458 of SEQ ID NO207. 341Ile Tyr Thr Ile
Leu Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp1 5 10
1534215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
342Tyr Thr Ile Leu Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile1 5
10 1534315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
343Thr Ile Leu Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile His1 5
10 1534415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
344Ile Leu Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile His His1 5
10 1534515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
345Leu Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile His His Leu1 5
10 1534615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
346Asp Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile His His Leu Ser1 5
10 1534715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
347Lys Leu Gly Pro Trp Ser Pro Ile Asp Ile His His Leu Ser Cys1 5
10 1534815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
348Leu Gly Pro Trp Ser Pro Ile Asp Ile His His Leu Ser Cys Pro1 5
10 1534915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
349Gly Pro Trp Ser Pro Ile Asp Ile His His Leu Ser Cys Pro Asn1 5
10 1535015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
350Pro Trp Ser Pro Ile Asp Ile His His Leu Ser Cys Pro Asn Asn1 5
10 1535115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
351Trp Ser Pro Ile Asp Ile His His Leu Ser Cys Pro Asn Asn Leu1 5
10 1535215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
352Ser Pro Ile Asp Ile His His Leu Ser Cys Pro Asn Asn Leu Val1 5
10 1535315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
353Pro Ile Asp Ile His His Leu Ser Cys Pro Asn Asn Leu Val Val1 5
10 1535415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
354Ile Asp Ile His His Leu Ser Cys Pro Asn Asn Leu Val Val Glu1 5
10 1535515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
355Asp Ile His His Leu Ser Cys Pro Asn Asn Leu Val Val Glu Asp1 5
10 1535615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
356Ile His His Leu Ser Cys Pro Asn Asn Leu Val Val Glu Asp Glu1 5
10 1535715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
357His His Leu Ser Cys Pro Asn Asn Leu Val Val Glu Asp Glu Gly1 5
10 1535815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
358His Leu Ser Cys Pro Asn Asn Leu Val Val Glu Asp Glu Gly Cys1 5
10 1535915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
359Leu Ser Cys Pro Asn Asn Leu Val Val Glu Asp Glu Gly Cys Thr1 5
10 1536015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
360Ser Cys Pro Asn Asn Leu Val Val Glu Asp Glu Gly Cys Thr Asn1 5
10 1536115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
361Cys Pro Asn Asn Leu Val Val Glu Asp Glu Gly Cys Thr Asn Leu1 5
10 1536215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
362Pro Asn Asn Leu Val Val Glu Asp Glu Gly Cys Thr Asn Leu Ser1 5
10 1536315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus
strain ERA (SEQ ID NO207), wherein the extracellular domain of
glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
363Asn Asn Leu Val Val Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly1 5
10 1536415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
364Asn Leu Val Val Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe1 5
10 1536515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
365Leu Val Val Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser1 5
10 1536615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
366Val Val Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr1 5
10 1536715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
367Val Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met1 5
10 1536815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
368Glu Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu1 5
10 1536915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
369Asp Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu1 5
10 1537015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
370Glu Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys1 5
10 1537115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
371Gly Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys Val1 5
10 1537215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
372Cys Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys Val Gly1 5
10 1537315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
373Thr Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr1 5
10 1537415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
374Asn Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile1 5
10 1537515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
375Leu Ser Gly Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu1 5
10 1537615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
376Ser Gly Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu Ala1 5
10 1537715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
377Gly Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile1 5
10 1537815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
378Phe Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys1 5
10 1537915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
379Ser Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys Met1 5
10 1538015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
380Tyr Met Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys Met Asn1 5
10 1538115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
381Met Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly1 5
10 1538215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
382Glu Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe1 5
10 1538315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
383Leu Lys Val Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe Thr1 5
10 1538415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
384Lys Val Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe Thr Cys1 5
10 1538515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
385Val Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe Thr Cys Thr1 5
10 1538615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
386Gly Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe Thr Cys Thr Gly1 5
10 1538715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
387Tyr Ile Leu Ala Ile Lys Met Asn Gly Phe Thr Cys Thr Gly Val1 5
10 1538815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
388Ile Leu Ala Ile Lys Met Asn Gly Phe Thr Cys Thr Gly Val Val1 5
10 1538915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
389Leu Ala Ile Lys Met Asn Gly Phe Thr Cys Thr Gly Val Val Thr1 5
10 1539015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
390Ala Ile Lys Met Asn Gly Phe Thr Cys Thr Gly Val Val Thr Glu1 5
10 1539115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
391Ile Lys Met Asn Gly Phe Thr Cys Thr Gly Val Val Thr Glu Ala1 5
10 1539215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
392Lys Met Asn Gly Phe Thr Cys Thr Gly Val Val Thr Glu Ala Glu1 5
10 1539315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
393Met Asn Gly Phe Thr Cys Thr Gly Val Val Thr Glu Ala Glu Asn1 5
10 1539415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
394Asn Gly Phe Thr Cys Thr Gly Val Val Thr Glu Ala Glu Asn Tyr1 5
10 1539515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
395Gly Phe Thr Cys Thr Gly Val Val Thr Glu Ala Glu Asn Tyr Thr1 5
10 1539615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
396Phe Thr Cys Thr Gly Val Val Thr Glu Ala Glu Asn Tyr Thr Asn1 5
10 1539715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
397Thr Cys Thr Gly Val Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe1 5
10 1539815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
398Cys Thr Gly Val Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val1 5
10 1539915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
399Thr Gly Val Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly1 5
10 1540015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
400Gly Val Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr1 5
10 1540115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
401Val Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val1 5
10 1540215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
402Val Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr1 5
10 1540315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
403Thr Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr1 5
10 1540415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
404Glu Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr Thr1 5
10 1540515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
405Ala Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr Thr Phe1 5
10 1540615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
406Glu Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr Thr Phe Lys1 5
10 1540715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
407Asn Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr Thr Phe Lys Arg1 5
10 1540815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
408Tyr Thr Asn Phe Val Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys1 5
10
1540915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
409Thr Asn Phe Val Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys His1 5
10 1541015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
410Asn Phe Val Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys His Phe1 5
10 1541115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
411Phe Val Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys His Phe Arg1 5
10 1541215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
412Val Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys His Phe Arg Pro1 5
10 1541315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
413Gly Tyr Val Thr Thr Thr Phe Lys Arg Lys His Phe Arg Pro Thr1 5
10 1541415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
414Tyr Val Thr Thr Thr Phe Lys Arg Lys His Phe Arg Pro Thr Pro1 5
10 1541515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
415Val Thr Thr Thr Phe Lys Arg Lys His Phe Arg Pro Thr Pro Asp1 5
10 1541615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
416Thr Thr Thr Phe Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala1 5
10 1541715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
417Thr Thr Phe Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala Cys1 5
10 1541815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
418Thr Phe Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala Cys Arg1 5
10 1541915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
419Phe Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala1 5
10 1542015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
420Lys Arg Lys His Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala1 5
10 1542115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
421Arg Lys His Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr1 5
10 1542215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
422Lys His Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn1 5
10 1542315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
423His Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp1 5
10 1542415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
424Phe Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys1 5
10 1542515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
425Arg Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met1 5
10 1542615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
426Pro Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala1 5
10 1542715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
427Thr Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly1 5
10 1542815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
428Pro Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp1 5
10 1542915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
429Asp Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro1 5
10 1543015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
430Ala Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg1 5
10 1543115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
431Cys Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr1 5
10 1543215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
432Arg Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu1 5
10 1543315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
433Ala Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu1 5
10 1543415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
434Ala Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser1 5
10 1543515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
435Tyr Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu1 5
10 1543615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
436Asn Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu His1 5
10 1543715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
437Trp Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu His Asn1 5
10 1543815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
438Lys Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu His Asn Pro1 5
10 1543915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
439Met Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr1 5
10 1544015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
440Ala Gly Asp Pro Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro1 5
10 1544115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
441Gly Asp Pro Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro Asp1 5
10 1544215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
442Asp Pro Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr1 5
10 1544315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
443Pro Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg1 5
10 1544415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
444Arg Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp1 5
10 1544515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
445Tyr Glu Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu1 5
10 1544615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
446Glu Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg1 5
10 1544715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
447Glu Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr1 5
10 1544815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
448Ser Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val1 5
10 1544915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
449Leu His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys1 5
10 1545015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
450His Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys Thr1 5
10 1545115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
451Asn Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys Thr Thr1 5
10 1545215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
452Pro Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys Thr Thr Lys1 5
10 1545315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
453Tyr Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys Thr Thr Lys Glu1 5
10 1545415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids
20-458 of SEQ ID NO207. 454Pro Asp Tyr Arg Trp Leu Arg Thr Val Lys
Thr Thr Lys Glu Ser1 5 10 1545515PRTArtificial Sequence15
contiguous and consecutive amino acids from the extracellular
domain of glycoprotein G of rabies virus strain ERA (SEQ ID NO207),
wherein the extracellular domain of glycoprotein G consists of
amino acids 20-458 of SEQ ID NO207. 455Asp Tyr Arg Trp Leu Arg Thr
Val Lys Thr Thr Lys Glu Ser Leu1 5 10 1545615PRTArtificial
Sequence15 contiguous and consecutive amino acids from the
extracellular domain of glycoprotein G of rabies virus strain ERA
(SEQ ID NO207), wherein the extracellular domain of glycoprotein G
consists of amino acids 20-458 of SEQ ID NO207. 456Tyr Arg Trp Leu
Arg Thr Val Lys Thr Thr Lys Glu Ser Leu Val1 5 10
1545715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
457Arg Trp Leu Arg Thr Val Lys Thr Thr Lys Glu Ser Leu Val Ile1 5
10 1545815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
458Trp Leu Arg Thr Val Lys Thr Thr Lys Glu Ser Leu Val Ile Ile1 5
10 1545915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
459Leu Arg Thr Val Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser1 5
10 1546015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
460Arg Thr Val Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro1 5
10 1546115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
461Thr Val Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser1 5
10 1546215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
462Val Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val1 5
10 1546315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
463Lys Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala1 5
10 1546415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
464Thr Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala Asp1 5
10 1546515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
465Thr Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala Asp Leu1 5
10 1546615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
466Lys Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala Asp Leu Asp1 5
10 1546715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
467Glu Ser Leu Val Ile Ile Ser Pro Ser Val Ala Asp Leu Asp Pro1 5
10 1546815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
468Ser Leu Val Ile Ile Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr1 5
10 1546915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
469Leu Val Ile Ile Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp1 5
10 1547015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
470Val Ile Ile Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg1 5
10 1547115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
471Ile Ile Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser1 5
10 1547215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
472Ile Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu1 5
10 1547315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
473Ser Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu His1 5
10 1547415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
474Pro Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu His Ser1 5
10 1547515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
475Ser Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg1 5
10 1547615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
476Val Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val1 5
10 1547715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
477Ala Asp Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val Phe1 5
10 1547815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
478Asp Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val Phe Pro1 5
10 1547915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
479Leu Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val Phe Pro Ser1 5
10 1548015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
480Asp Pro Tyr Asp Arg Ser Leu His Ser Arg Val Phe Pro Ser Gly1 5
10 1548115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
481Pro Tyr Asp Arg Ser Leu His Ser Arg Val Phe Pro Ser Gly Lys1 5
10 1548215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
482Tyr Asp Arg Ser Leu His Ser Arg Val Phe Pro Ser Gly Lys Cys1 5
10 1548315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
483Asp Arg Ser Leu His Ser Arg Val Phe Pro Ser Gly Lys Cys Ser1 5
10 1548415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
484Arg Ser Leu His Ser Arg Val Phe Pro Ser Gly Lys Cys Ser Gly1 5
10 1548515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
485Ser Leu His Ser Arg Val Phe Pro Ser Gly Lys Cys Ser Gly Val1 5
10 1548615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
486Leu His Ser Arg Val Phe Pro Ser Gly Lys Cys Ser Gly Val Ala1 5
10 1548715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
487His Ser Arg Val Phe Pro Ser Gly Lys Cys Ser Gly Val Ala Val1 5
10 1548815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
488Ser Arg Val Phe Pro Ser Gly Lys Cys Ser Gly Val Ala Val Ser1 5
10 1548915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
489Arg Val Phe Pro Ser Gly Lys Cys Ser Gly Val Ala Val Ser Ser1 5
10 1549015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
490Val Phe Pro Ser Gly Lys Cys Ser Gly Val Ala Val Ser Ser Thr1 5
10 1549115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
491Phe Pro Ser Gly Lys Cys Ser Gly Val Ala Val Ser Ser Thr Tyr1 5
10 1549215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
492Pro Ser Gly Lys Cys Ser Gly Val Ala Val Ser Ser Thr Tyr Cys1 5
10 1549315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
493Ser Gly Lys Cys Ser Gly Val Ala Val Ser Ser Thr Tyr Cys Ser1 5
10 1549415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
494Gly Lys Cys Ser Gly Val Ala Val Ser Ser Thr Tyr Cys Ser Thr1 5
10 1549515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
495Lys Cys Ser Gly Val Ala Val Ser Ser Thr Tyr Cys Ser Thr Asn1 5
10 1549615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
496Cys Ser Gly Val Ala Val Ser Ser Thr Tyr Cys Ser Thr Asn His1 5
10 1549715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
497Ser Gly Val Ala Val Ser Ser Thr Tyr Cys Ser Thr Asn His Asp1 5
10 1549815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
498Gly Val Ala Val Ser Ser Thr Tyr Cys Ser Thr Asn His Asp Tyr1 5
10 1549915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
499Val Ala Val Ser Ser Thr Tyr Cys Ser Thr Asn His Asp Tyr Thr1 5
10 1550015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain
of glycoprotein G of rabies virus strain ERA (SEQ ID NO207),
wherein the extracellular domain of glycoprotein G consists of
amino acids 20-458 of SEQ ID NO207. 500Ala Val Ser Ser Thr Tyr Cys
Ser Thr Asn His Asp Tyr Thr Ile1 5 10 1550115PRTArtificial
Sequence15 contiguous and consecutive amino acids from the
extracellular domain of glycoprotein G of rabies virus strain ERA
(SEQ ID NO207), wherein the extracellular domain of glycoprotein G
consists of amino acids 20-458 of SEQ ID NO207. 501Val Ser Ser Thr
Tyr Cys Ser Thr Asn His Asp Tyr Thr Ile Trp1 5 10
1550215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
502Ser Ser Thr Tyr Cys Ser Thr Asn His Asp Tyr Thr Ile Trp Met1 5
10 1550315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
503Ser Thr Tyr Cys Ser Thr Asn His Asp Tyr Thr Ile Trp Met Pro1 5
10 1550415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
504Thr Tyr Cys Ser Thr Asn His Asp Tyr Thr Ile Trp Met Pro Glu1 5
10 1550515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
505Tyr Cys Ser Thr Asn His Asp Tyr Thr Ile Trp Met Pro Glu Asn1 5
10 1550615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
506Cys Ser Thr Asn His Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro1 5
10 1550715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
507Ser Thr Asn His Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg1 5
10 1550815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
508Thr Asn His Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg Leu1 5
10 1550915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
509Asn His Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg Leu Gly1 5
10 1551015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
510His Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg Leu Gly Met1 5
10 1551115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
511Asp Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg Leu Gly Met Ser1 5
10 1551215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
512Tyr Thr Ile Trp Met Pro Glu Asn Pro Arg Leu Gly Met Ser Cys1 5
10 1551315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
513Thr Ile Trp Met Pro Glu Asn Pro Arg Leu Gly Met Ser Cys Asp1 5
10 1551415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
514Ile Trp Met Pro Glu Asn Pro Arg Leu Gly Met Ser Cys Asp Ile1 5
10 1551515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
515Trp Met Pro Glu Asn Pro Arg Leu Gly Met Ser Cys Asp Ile Phe1 5
10 1551615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
516Met Pro Glu Asn Pro Arg Leu Gly Met Ser Cys Asp Ile Phe Thr1 5
10 1551715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
517Pro Glu Asn Pro Arg Leu Gly Met Ser Cys Asp Ile Phe Thr Asn1 5
10 1551815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
518Glu Asn Pro Arg Leu Gly Met Ser Cys Asp Ile Phe Thr Asn Ser1 5
10 1551915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
519Asn Pro Arg Leu Gly Met Ser Cys Asp Ile Phe Thr Asn Ser Arg1 5
10 1552015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
520Pro Arg Leu Gly Met Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly1 5
10 1552115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
521Arg Leu Gly Met Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys1 5
10 1552215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
522Leu Gly Met Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg1 5
10 1552315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
523Gly Met Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala1 5
10 1552415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
524Met Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser1 5
10 1552515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
525Ser Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys1 5
10 1552615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
526Cys Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly1 5
10 1552715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
527Asp Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser1 5
10 1552815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
528Ile Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu1 5
10 1552915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
529Phe Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr1 5
10 1553015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
530Thr Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys1 5
10 1553115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
531Asn Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly1 5
10 1553215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
532Ser Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe1 5
10 1553315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
533Arg Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe Val1 5
10 1553415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
534Gly Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe Val Asp1 5
10 1553515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
535Lys Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe Val Asp Glu1 5
10 1553615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
536Arg Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe Val Asp Glu Arg1 5
10 1553715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
537Ala Ser Lys Gly Ser Glu Thr Cys Gly Phe Val Asp Glu Arg Gly1 5
10 1553815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
538Ser Lys Gly Ser Glu Thr Cys Gly Phe Val Asp Glu Arg Gly Leu1 5
10 1553915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
539Lys Gly Ser Glu Thr Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr1 5
10 1554015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
540Gly Ser Glu Thr Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys1 5
10 1554115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
541Ser Glu Thr Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser1 5
10 1554215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
542Glu Thr Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu1 5
10 1554315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
543Thr Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys1 5
10 1554415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
544Cys Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly1 5
10 1554515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
545Gly Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala1
5
10 1554615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
546Phe Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys1 5
10 1554715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
547Val Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys1 5
10 1554815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
548Asp Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu1 5
10 1554915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
549Glu Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys1 5
10 1555015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
550Arg Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu1 5
10 1555115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
551Gly Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys1 5
10 1555215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
552Leu Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys Gly1 5
10 1555315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
553Tyr Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys Gly Val1 5
10 1555415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
554Lys Ser Leu Lys Gly Ala Cys Lys Leu Lys Leu Cys Gly Val Leu1 5
10 1555515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
555Leu Cys Gly Val Leu Gly Leu Arg Leu Met Asp Gly Thr Trp Val1 5
10 1555615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
556Cys Gly Val Leu Gly Leu Arg Leu Met Asp Gly Thr Trp Val Ala1 5
10 1555715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
557Gly Val Leu Gly Leu Arg Leu Met Asp Gly Thr Trp Val Ala Met1 5
10 1555815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
558Val Leu Gly Leu Arg Leu Met Asp Gly Thr Trp Val Ala Met Gln1 5
10 1555915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
559Leu Gly Leu Arg Leu Met Asp Gly Thr Trp Val Ala Met Gln Thr1 5
10 1556015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
560Gly Leu Arg Leu Met Asp Gly Thr Trp Val Ala Met Gln Thr Ser1 5
10 1556115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
561Leu Arg Leu Met Asp Gly Thr Trp Val Ala Met Gln Thr Ser Asn1 5
10 1556215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
562Arg Leu Met Asp Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu1 5
10 1556315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
563Leu Met Asp Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr1 5
10 1556415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
564Met Asp Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys1 5
10 1556515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
565Asp Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp1 5
10 1556615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
566Gly Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys1 5
10 1556715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
567Thr Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro1 5
10 1556815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
568Trp Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro1 5
10 1556915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
569Val Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp1 5
10 1557015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
570Ala Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln1 5
10 1557115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
571Met Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu1 5
10 1557215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
572Gln Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu Val1 5
10 1557315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
573Thr Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu Val Asn1 5
10 1557415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
574Ser Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu Val Asn Leu1 5
10 1557515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
575Asn Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu Val Asn Leu His1 5
10 1557615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
576Glu Thr Lys Trp Cys Pro Pro Asp Gln Leu Val Asn Leu His Asp1 5
10 1557715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
577Thr Lys Trp Cys Pro Pro Asp Gln Leu Val Asn Leu His Asp Phe1 5
10 1557815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
578Lys Trp Cys Pro Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg1 5
10 1557915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
579Trp Cys Pro Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser1 5
10 1558015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
580Cys Pro Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp1 5
10 1558115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
581Pro Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu1 5
10 1558215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
582Pro Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu Ile1 5
10 1558315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
583Asp Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu Ile Glu1 5
10 1558415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
584Gln Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu Ile Glu His1 5
10 1558515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
585Leu Val Asn Leu His Asp Phe Arg Ser Asp Glu Ile Glu His Leu1 5
10 1558615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
586Val Asn Leu His Asp Phe Arg Ser Asp Glu Ile Glu His Leu Val1 5
10 1558715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
587Asn Leu His Asp Phe Arg Ser Asp Glu Ile Glu His Leu Val Val1 5
10 1558815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
588Leu His Asp Phe Arg Ser Asp Glu Ile Glu His Leu Val Val Glu1 5
10 1558915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
589His Asp Phe Arg Ser Asp Glu Ile Glu His Leu Val Val Glu Glu1 5
10 1559015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
590Asp Phe Arg Ser Asp Glu Ile Glu His Leu Val Val Glu Glu Leu1 5
10 1559115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of
glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
591Phe Arg Ser Asp Glu Ile Glu His Leu Val Val Glu Glu Leu Val1 5
10 1559215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
592Arg Ser Asp Glu Ile Glu His Leu Val Val Glu Glu Leu Val Arg1 5
10 1559315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
593Ser Asp Glu Ile Glu His Leu Val Val Glu Glu Leu Val Arg Lys1 5
10 1559415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
594Asp Glu Ile Glu His Leu Val Val Glu Glu Leu Val Arg Lys Arg1 5
10 1559515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
595Glu Ile Glu His Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu1 5
10 1559615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
596Ile Glu His Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu Glu1 5
10 1559715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
597Glu His Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu Glu Cys1 5
10 1559815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
598His Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu Glu Cys Leu1 5
10 1559915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
599Leu Val Val Glu Glu Leu Val Arg Lys Arg Glu Glu Cys Leu Asp1 5
10 1560015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
600Val Val Glu Glu Leu Val Arg Lys Arg Glu Glu Cys Leu Asp Ala1 5
10 1560115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
601Val Glu Glu Leu Val Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu1 5
10 1560215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
602Glu Glu Leu Val Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu1 5
10 1560315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
603Glu Leu Val Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser1 5
10 1560415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
604Leu Val Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile1 5
10 1560515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
605Val Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile Met1 5
10 1560615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
606Arg Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile Met Thr1 5
10 1560715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
607Lys Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile Met Thr Thr1 5
10 1560815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
608Arg Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile Met Thr Thr Lys1 5
10 1560915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
609Glu Glu Cys Leu Asp Ala Leu Glu Ser Ile Met Thr Thr Lys Ser1 5
10 1561015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
610Glu Cys Leu Asp Ala Leu Glu Ser Ile Met Thr Thr Lys Ser Val1 5
10 1561115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
611Cys Leu Asp Ala Leu Glu Ser Ile Met Thr Thr Lys Ser Val Ser1 5
10 1561215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
612Leu Asp Ala Leu Glu Ser Ile Met Thr Thr Lys Ser Val Ser Phe1 5
10 1561315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
613Asp Ala Leu Glu Ser Ile Met Thr Thr Lys Ser Val Ser Phe Arg1 5
10 1561415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
614Ala Leu Glu Ser Ile Met Thr Thr Lys Ser Val Ser Phe Arg Arg1 5
10 1561515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
615Leu Glu Ser Ile Met Thr Thr Lys Ser Val Ser Phe Arg Arg Leu1 5
10 1561615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
616Glu Ser Ile Met Thr Thr Lys Ser Val Ser Phe Arg Arg Leu Ser1 5
10 1561715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
617Ser Ile Met Thr Thr Lys Ser Val Ser Phe Arg Arg Leu Ser His1 5
10 1561815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
618Ile Met Thr Thr Lys Ser Val Ser Phe Arg Arg Leu Ser His Leu1 5
10 1561915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
619Met Thr Thr Lys Ser Val Ser Phe Arg Arg Leu Ser His Leu Arg1 5
10 1562015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
620Thr Thr Lys Ser Val Ser Phe Arg Arg Leu Ser His Leu Arg Lys1 5
10 1562115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
621Thr Lys Ser Val Ser Phe Arg Arg Leu Ser His Leu Arg Lys Leu1 5
10 1562215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
622Lys Ser Val Ser Phe Arg Arg Leu Ser His Leu Arg Lys Leu Val1 5
10 1562315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
623Ser Val Ser Phe Arg Arg Leu Ser His Leu Arg Lys Leu Val Pro1 5
10 1562415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
624Val Ser Phe Arg Arg Leu Ser His Leu Arg Lys Leu Val Pro Gly1 5
10 1562515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
625Ser Phe Arg Arg Leu Ser His Leu Arg Lys Leu Val Pro Gly Phe1 5
10 1562615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
626Phe Arg Arg Leu Ser His Leu Arg Lys Leu Val Pro Gly Phe Gly1 5
10 1562715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
627Arg Arg Leu Ser His Leu Arg Lys Leu Val Pro Gly Phe Gly Lys1 5
10 1562815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
628Arg Leu Ser His Leu Arg Lys Leu Val Pro Gly Phe Gly Lys Ala1 5
10 1562915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
629Leu Ser His Leu Arg Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr1 5
10 1563015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
630Ser His Leu Arg Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr1 5
10 1563115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
631His Leu Arg Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile1 5
10 1563215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
632Leu Arg Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe1 5
10 1563315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
633Arg Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn1 5
10 1563415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
634Lys Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn Lys1 5
10 1563515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
635Leu Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn Lys Thr1 5
10 1563615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
636Val Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn Lys Thr Leu1 5
10 1563715PRTArtificial Sequence15 contiguous and consecutive amino
acids
from the extracellular domain of glycoprotein G of rabies virus
strain ERA (SEQ ID NO207), wherein the extracellular domain of
glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
637Pro Gly Phe Gly Lys Ala Tyr Thr Ile Phe Asn Lys Thr Leu Met1 5
10 1563815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
638Asn Lys Thr Leu Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg1 5
10 1563915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
639Lys Thr Leu Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg Thr1 5
10 1564015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
640Thr Leu Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg Thr Trp1 5
10 1564115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
641Leu Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg Thr Trp Asn1 5
10 1564215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
642Met Glu Ala Asp Ala His Tyr Lys Ser Val Arg Thr Trp Asn Glu1 5
10 1564315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
643Glu Ala Asp Ala His Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile1 5
10 1564415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
644Ala Asp Ala His Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile Leu1 5
10 1564515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
645Asp Ala His Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile Leu Pro1 5
10 1564615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
646Ala His Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile Leu Pro Ser1 5
10 1564715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
647His Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys1 5
10 1564815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
648Tyr Lys Ser Val Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly1 5
10 1564915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
649Lys Ser Val Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys1 5
10 1565015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
650Ser Val Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu1 5
10 1565115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
651Val Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg1 5
10 1565215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
652Arg Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val1 5
10 1565315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
653Thr Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly1 5
10 1565415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
654Trp Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly1 5
10 1565515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
655Asn Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly Arg1 5
10 1565615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
656Glu Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly Arg Cys1 5
10 1565715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
657Ile Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly Arg Cys His1 5
10 1565815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
658Leu Pro Ser Lys Gly Cys Leu Arg Val Gly Gly Arg Cys His Pro1 5
10 1565915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
659Pro Ser Lys Gly Cys Leu Arg Val Gly Gly Arg Cys His Pro His1 5
10 1566015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
660Ser Lys Gly Cys Leu Arg Val Gly Gly Arg Cys His Pro His Val1 5
10 1566115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
661Lys Gly Cys Leu Arg Val Gly Gly Arg Cys His Pro His Val Asn1 5
10 1566215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
662Gly Cys Leu Arg Val Gly Gly Arg Cys His Pro His Val Asn Gly1 5
10 1566315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
663Cys Leu Arg Val Gly Gly Arg Cys His Pro His Val Asn Gly Val1 5
10 1566415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
664Leu Arg Val Gly Gly Arg Cys His Pro His Val Asn Gly Val Phe1 5
10 1566515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
665Arg Val Gly Gly Arg Cys His Pro His Val Asn Gly Val Phe Phe1 5
10 1566615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
666Val Gly Gly Arg Cys His Pro His Val Asn Gly Val Phe Phe Asn1 5
10 1566715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
667Gly Gly Arg Cys His Pro His Val Asn Gly Val Phe Phe Asn Gly1 5
10 1566815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
668Gly Arg Cys His Pro His Val Asn Gly Val Phe Phe Asn Gly Ile1 5
10 1566915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
669Arg Cys His Pro His Val Asn Gly Val Phe Phe Asn Gly Ile Ile1 5
10 1567015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
670Cys His Pro His Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu1 5
10 1567115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
671His Pro His Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu Gly1 5
10 1567215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
672Pro His Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu Gly Pro1 5
10 1567315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
673His Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp1 5
10 1567415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
674Val Asn Gly Val Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly1 5
10 1567515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
675Asn Gly Val Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn1 5
10 1567615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
676Gly Val Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn Val1 5
10 1567715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
677Val Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn Val Leu1 5
10 1567815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
678Phe Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn Val Leu Ile1 5
10 1567915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
679Phe Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn Val Leu Ile Pro1 5
10 1568015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
680Asn Gly Ile Ile Leu Gly Pro Asp Gly Asn Val Leu Ile Pro Glu1 5
10 1568115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
681Gly Ile Ile Leu Gly Pro Asp Gly Asn Val Leu Ile Pro Glu Met1 5
10 1568215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
682Ile Ile Leu Gly Pro Asp Gly Asn Val Leu Ile
Pro Glu Met Gln1 5 10 1568315PRTArtificial Sequence15 contiguous
and consecutive amino acids from the extracellular domain of
glycoprotein G of rabies virus strain ERA (SEQ ID NO207), wherein
the extracellular domain of glycoprotein G consists of amino acids
20-458 of SEQ ID NO207. 683Ile Leu Gly Pro Asp Gly Asn Val Leu Ile
Pro Glu Met Gln Ser1 5 10 1568415PRTArtificial Sequence15
contiguous and consecutive amino acids from the extracellular
domain of glycoprotein G of rabies virus strain ERA (SEQ ID NO207),
wherein the extracellular domain of glycoprotein G consists of
amino acids 20-458 of SEQ ID NO207. 684Leu Gly Pro Asp Gly Asn Val
Leu Ile Pro Glu Met Gln Ser Ser1 5 10 1568515PRTArtificial
Sequence15 contiguous and consecutive amino acids from the
extracellular domain of glycoprotein G of rabies virus strain ERA
(SEQ ID NO207), wherein the extracellular domain of glycoprotein G
consists of amino acids 20-458 of SEQ ID NO207. 685Gly Pro Asp Gly
Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu1 5 10
1568615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
686Pro Asp Gly Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu Leu1 5
10 1568715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
687Asp Gly Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu Leu Gln1 5
10 1568815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
688Gly Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu Leu Gln Gln1 5
10 1568915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
689Asn Val Leu Ile Pro Glu Met Gln Ser Ser Leu Leu Gln Gln His1 5
10 1569015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
690Val Leu Ile Pro Glu Met Gln Ser Ser Leu Leu Gln Gln His Met1 5
10 1569115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
691Leu Ile Pro Glu Met Gln Ser Ser Leu Leu Gln Gln His Met Glu1 5
10 1569215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
692Ile Pro Glu Met Gln Ser Ser Leu Leu Gln Gln His Met Glu Leu1 5
10 1569315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
693Pro Glu Met Gln Ser Ser Leu Leu Gln Gln His Met Glu Leu Leu1 5
10 1569415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
694Glu Met Gln Ser Ser Leu Leu Gln Gln His Met Glu Leu Leu Glu1 5
10 1569515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
695Met Gln Ser Ser Leu Leu Gln Gln His Met Glu Leu Leu Glu Ser1 5
10 1569615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
696Gln Ser Ser Leu Leu Gln Gln His Met Glu Leu Leu Glu Ser Ser1 5
10 1569715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
697Ser Ser Leu Leu Gln Gln His Met Glu Leu Leu Glu Ser Ser Val1 5
10 1569815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
698Ser Leu Leu Gln Gln His Met Glu Leu Leu Glu Ser Ser Val Ile1 5
10 1569915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
699Leu Leu Gln Gln His Met Glu Leu Leu Glu Ser Ser Val Ile Pro1 5
10 1570015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
700Leu Gln Gln His Met Glu Leu Leu Glu Ser Ser Val Ile Pro Leu1 5
10 1570115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
701Gln Gln His Met Glu Leu Leu Glu Ser Ser Val Ile Pro Leu Val1 5
10 1570215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
702Gln His Met Glu Leu Leu Glu Ser Ser Val Ile Pro Leu Val His1 5
10 1570315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
703His Met Glu Leu Leu Glu Ser Ser Val Ile Pro Leu Val His Pro1 5
10 1570415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
704Met Glu Leu Leu Glu Ser Ser Val Ile Pro Leu Val His Pro Leu1 5
10 1570515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
705Glu Leu Leu Glu Ser Ser Val Ile Pro Leu Val His Pro Leu Ala1 5
10 1570615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
706Leu Leu Glu Ser Ser Val Ile Pro Leu Val His Pro Leu Ala Asp1 5
10 1570715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
707Leu Glu Ser Ser Val Ile Pro Leu Val His Pro Leu Ala Asp Pro1 5
10 1570815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
708Glu Ser Ser Val Ile Pro Leu Val His Pro Leu Ala Asp Pro Ser1 5
10 1570915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
709Ser Ser Val Ile Pro Leu Val His Pro Leu Ala Asp Pro Ser Thr1 5
10 1571015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
710Ser Val Ile Pro Leu Val His Pro Leu Ala Asp Pro Ser Thr Val1 5
10 1571115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
711Val Ile Pro Leu Val His Pro Leu Ala Asp Pro Ser Thr Val Phe1 5
10 1571215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
712Ile Pro Leu Val His Pro Leu Ala Asp Pro Ser Thr Val Phe Lys1 5
10 1571315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
713Pro Leu Val His Pro Leu Ala Asp Pro Ser Thr Val Phe Lys Asp1 5
10 1571415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
714Leu Val His Pro Leu Ala Asp Pro Ser Thr Val Phe Lys Asp Gly1 5
10 1571515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
715Val His Pro Leu Ala Asp Pro Ser Thr Val Phe Lys Asp Gly Asp1 5
10 1571615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
716His Pro Leu Ala Asp Pro Ser Thr Val Phe Lys Asp Gly Asp Glu1 5
10 1571715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
717Pro Leu Ala Asp Pro Ser Thr Val Phe Lys Asp Gly Asp Glu Ala1 5
10 1571815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
718Leu Ala Asp Pro Ser Thr Val Phe Lys Asp Gly Asp Glu Ala Glu1 5
10 1571915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
719Ala Asp Pro Ser Thr Val Phe Lys Asp Gly Asp Glu Ala Glu Asp1 5
10 1572015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
720Asp Pro Ser Thr Val Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe1 5
10 1572115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
721Pro Ser Thr Val Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe Val1 5
10 1572215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
722Ser Thr Val Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe Val Glu1 5
10 1572315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
723Thr Val Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe Val Glu Val1 5
10 1572415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
724Val Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe Val Glu Val His1 5
10 1572515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
725Phe Lys Asp Gly Asp Glu Ala Glu Asp Phe Val Glu Val His Leu1 5
10 1572615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
726Lys Asp Gly Asp Glu Ala Glu Asp Phe Val Glu Val His Leu Pro1 5
10 1572715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
727Asp Gly Asp Glu Ala Glu Asp Phe Val Glu Val His Leu Pro Asp1 5
10 1572815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein
the extracellular domain of glycoprotein G consists of amino acids
20-458 of SEQ ID NO207. 728Gly Asp Glu Ala Glu Asp Phe Val Glu Val
His Leu Pro Asp Val1 5 10 1572915PRTArtificial Sequence15
contiguous and consecutive amino acids from the extracellular
domain of glycoprotein G of rabies virus strain ERA (SEQ ID NO207),
wherein the extracellular domain of glycoprotein G consists of
amino acids 20-458 of SEQ ID NO207. 729Asp Glu Ala Glu Asp Phe Val
Glu Val His Leu Pro Asp Val His1 5 10 1573015PRTArtificial
Sequence15 contiguous and consecutive amino acids from the
extracellular domain of glycoprotein G of rabies virus strain ERA
(SEQ ID NO207), wherein the extracellular domain of glycoprotein G
consists of amino acids 20-458 of SEQ ID NO207. 730Glu Ala Glu Asp
Phe Val Glu Val His Leu Pro Asp Val His Asn1 5 10
1573115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
731Ala Glu Asp Phe Val Glu Val His Leu Pro Asp Val His Asn Gln1 5
10 1573215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
732Glu Asp Phe Val Glu Val His Leu Pro Asp Val His Asn Gln Val1 5
10 1573315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
733Asp Phe Val Glu Val His Leu Pro Asp Val His Asn Gln Val Ser1 5
10 1573415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
734Phe Val Glu Val His Leu Pro Asp Val His Asn Gln Val Ser Gly1 5
10 1573515PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
735Val Glu Val His Leu Pro Asp Val His Asn Gln Val Ser Gly Val1 5
10 1573615PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
736Glu Val His Leu Pro Asp Val His Asn Gln Val Ser Gly Val Asp1 5
10 1573715PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
737Val His Leu Pro Asp Val His Asn Gln Val Ser Gly Val Asp Leu1 5
10 1573815PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
738His Leu Pro Asp Val His Asn Gln Val Ser Gly Val Asp Leu Gly1 5
10 1573915PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
739Leu Pro Asp Val His Asn Gln Val Ser Gly Val Asp Leu Gly Leu1 5
10 1574015PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
740Pro Asp Val His Asn Gln Val Ser Gly Val Asp Leu Gly Leu Pro1 5
10 1574115PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
741Asp Val His Asn Gln Val Ser Gly Val Asp Leu Gly Leu Pro Asn1 5
10 1574215PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
742Val His Asn Gln Val Ser Gly Val Asp Leu Gly Leu Pro Asn Trp1 5
10 1574315PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
743His Asn Gln Val Ser Gly Val Asp Leu Gly Leu Pro Asn Trp Gly1 5
10 1574415PRTArtificial Sequence15 contiguous and consecutive amino
acids from the extracellular domain of glycoprotein G of rabies
virus strain ERA (SEQ ID NO207), wherein the extracellular domain
of glycoprotein G consists of amino acids 20-458 of SEQ ID NO207.
744Asn Gln Val Ser Gly Val Asp Leu Gly Leu Pro Asn Trp Gly Lys1 5
10 1574521DNARabies virus - part of glycoprotein of CVS-11
745cggacctgga atgagatcat c 2174621DNARabies virus - part of
glycoprotein of E98-2, 4, 5, 6, 7 746cggacctggg atgagatcat c
2174718PRTRabies virus - part of glycoprotein of CVS-11 747His Tyr
Lys Ser Val Arg Thr Trp Asn Glu Ile Ile Pro Ser Lys Gly1 5 10 15Cys
Leu74818PRTRabies virus - part of glycoprotein of E98-2, 4, 5, 6, 7
748His Tyr Lys Ser Val Arg Thr Trp Asp Glu Ile Ile Pro Ser Lys Gly1
5 10 15Cys Leu
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