U.S. patent application number 11/886899 was filed with the patent office on 2009-01-15 for adhesive sheet.
This patent application is currently assigned to LINTEC Corporation. Invention is credited to Toshihiko Sakuma, Kouji Tabata.
Application Number | 20090017241 11/886899 |
Document ID | / |
Family ID | 37023865 |
Filed Date | 2009-01-15 |
United States Patent
Application |
20090017241 |
Kind Code |
A1 |
Sakuma; Toshihiko ; et
al. |
January 15, 2009 |
Adhesive sheet
Abstract
The present invention provide an adhesive sheet for attaching to
a plasticized vinyl chloride resin article such as a blood bag made
of a plasticized vinyl chloride resin, and having a center-line
surface roughness Ra of 1.0 .mu.m or higher, which comprises a film
substrate and a heat-sensitive adhesive layer formed on a backside
surface of the film substrate, wherein the heat-sensitive adhesive
layer is composed of a resin containing a crystalline polyester
resin as a main component. The adhesive sheet of the present
invention is excellent in adhesive property when the adhesive sheet
is attached to the article made of a plasticized vinyl chloride
resin. The adhesive strength of the adhesive sheet of the present
invention is not decreased even after an autoclave treatment or a
storage at a low temperature. At the result, the adhesive sheet of
the present invention does not cause lifting or peeling and is
excellent in blocking resistance.
Inventors: |
Sakuma; Toshihiko; (Saitama,
JP) ; Tabata; Kouji; (Saitama, JP) |
Correspondence
Address: |
SUGHRUE MION, PLLC
2100 PENNSYLVANIA AVENUE, N.W., SUITE 800
WASHINGTON
DC
20037
US
|
Assignee: |
LINTEC Corporation
Itabashi-ku
JP
|
Family ID: |
37023865 |
Appl. No.: |
11/886899 |
Filed: |
March 20, 2006 |
PCT Filed: |
March 20, 2006 |
PCT NO: |
PCT/JP2006/306051 |
371 Date: |
September 21, 2007 |
Current U.S.
Class: |
428/35.4 ;
428/349 |
Current CPC
Class: |
C09J 2467/00 20130101;
C08L 2666/18 20130101; Y10T 428/1341 20150115; C09J 167/00
20130101; C09J 2467/00 20130101; C09J 2467/00 20130101; C08L
2666/18 20130101; C09J 7/35 20180101; C08L 67/00 20130101; Y10T
428/2826 20150115; C09J 167/00 20130101 |
Class at
Publication: |
428/35.4 ;
428/349 |
International
Class: |
B32B 7/12 20060101
B32B007/12; B32B 1/02 20060101 B32B001/02; C09J 167/00 20060101
C09J167/00 |
Foreign Application Data
Date |
Code |
Application Number |
Mar 23, 2005 |
JP |
2005-084967 |
Claims
1. An adhesive sheet for attaching to a plasticized vinyl chloride
resin article, which comprises a film substrate and a
heat-sensitive adhesive layer formed on a backside surface of the
film substrate, wherein the heat-sensitive adhesive layer is
composed of a resin comprising a crystalline polyester resin as a
main component.
2. The adhesive sheet as claimed in claim 1, wherein a content
ratio of the crystalline polyester resin comprised in the resin
composing the heat-sensitive adhesive layer is 50 to 100 percent by
mass.
3. The adhesive sheet as claimed in claim 1, wherein the resin
composing the heat-sensitive adhesive layer is composed of 50 to
100 percent by mass of the crystalline polyester resin and 50 to 0
percent by mass of an amorphous polyester resin.
4. The adhesive sheet as claimed in claim 1, wherein a melting
point of the crystalline polyester resin is 50 to 200.degree.
C.
5. The adhesive sheet as claimed in claim 3, wherein a glass
transition temperature of the amorphous polyester resin is 10 to
90.degree. C.
6. The adhesive sheet as claimed in claim 1, wherein the adhesive
sheet is an adhesive sheet for attaching to a plasticized vinyl
chloride resin article having a center-line surface roughness Ra of
1.0 .mu.m or higher.
7. The adhesive sheet as claimed in claim 6, wherein the
plasticized vinyl chloride resin article is a blood bag made of a
plasticized vinyl chloride resin.
Description
TECHNICAL FIELD
[0001] The present invention relates to an adhesive sheet and
specifically an adhesive sheet having an excellent adhesive
property, which can be attached to a plasticized vinyl chloride
resin article, more particularly a blood bag made of a plasticized
vinyl chloride resin.
BACKGROUND ART
[0002] As a blood bag in which blood is put, blood bags made of a
plasticized vinyl chloride resin have widely been used to date. The
blood bag is used with a label described about information of blood
being attached thereon.
[0003] After the attached label is subjected to an autoclave
treatment or a steam sterilization at 120.degree. C. for about 30
minutes, there is an instance where plasticizers contained in a
plasticized vinyl chloride resin move into an adhesive layer to
lower the adhesive property of the label, and lifting or peeling of
the label take place. When the label is peeled off from the blood
bag, information of blood is lost, causing a serious problem.
Further, even in this case, if the label is merely peeled off, the
blood bag that the label was peeled off may be scrapped, but in the
case where a plurality of labels are peeled off without someone's
knowledge for some reason, and the labels are wrongly attached to
one of the other blood bags again, a blood bag with wrong blood
information is used, resulting in a further fatal problem.
[0004] Moreover, as a label for a blood bag, there is used a label
on which a trade name, volume, ingredient representation, and
manufacture etc. are printed. In this field, a bar-code management
system is established, the label that bar-code are printed is
required. As a label for a blood bag, conventionally a label of
paper as a substrate has been mainly used. However, when such label
is in application to a blood bag, there have been problems that in
treatment by a centrifugal separator to separate a normal blood
cell component, a blood plasma component and the other component,
due to lack of strength of the label substrate, the label cannot
endure a centrifugal force and is broken, cracked, or through
friction of the printed surface against the wall surface or the
blood bag surface, information such as bar-code becomes too unclear
to read by a bar-code reader. Therefore, there has increasingly
desired a plastic film substrate being less influenced by moisture
than a paper substrate, and resistant to rubbing and strong/tough.
However, although a plastic film substrate has the superiority
described above, it has defect that lifting or peeling occurs more
easily than a paper substrate in an autoclave treatment or a steam
sterilization treatment and a centrifugal separation treatment.
Further, when a heat sealing label is based on a plastic film
substrate of liner-less roll type, it has a defect that blocking
occurs more easily than a paper substrate.
[0005] To solve these problems, there is proposed a label for a
blood bag based on a substrate film which is a microporous plastic
film with a matrix structure surrounding pores connecting each
other so that gas can flow in said blood bag and flow out through a
region labeled (see Japanese Patent No. 3404573). Lifting and
peeling in an autoclave treatment can be suppressed, however, there
has been a problem that it is difficult to obtain the label with
excellent blocking resistance.
DISCLOSURE OF THE INVENTION
[0006] An object of the present invention is to provide, an
adhesive sheet which has superior adhesive property when the
adhesive sheet is attached to a plasticized vinyl chloride resin
article, does not decrease strength even after an autoclave
treatment or a storage at a low temperature, does not cause lifting
or peeling and has excellent blocking resistance.
[0007] The present inventors have perfected the present invention
by discovering, as a result of a diligent study carried out to
solve the above-described problems, that the above-described
problems can be solved by forming a heat-sensitive adhesive layer
composed of a resin comprising a crystalline polyester resin as a
main component, on a backside surface of the film substrate.
[0008] Thus, the present invention provides an adhesive sheet for
attaching to a plasticized vinyl chloride resin article, which
comprises a film substrate and a heat-sensitive adhesive layer
formed on a backside surface of the film substrate, wherein the
heat-sensitive adhesive layer is composed of a resin comprising a
crystalline polyester resin as a main component.
[0009] The present invention provides the adhesive sheet as
described above, wherein a content ratio of the crystalline
polyester resin comprised in the resin composing the heat-sensitive
adhesive layer is 50 to 100 percent by mass.
[0010] The present invention provides the adhesive sheet as
described above, wherein the resin composing the heat-sensitive
adhesive layer is composed of 50 to 100 percent by mass of the
crystalline polyester resin and 50 to 0 percent by mass of an
amorphous polyester resin.
[0011] Additionally, the present invention provides the adhesive
sheet as described above, wherein a melting point of the
crystalline polyester resin is 50 to 200.degree. C.
[0012] Also, the present invention provides the adhesive sheet as
described above, wherein a glass transition temperature of the
amorphous polyester resin is 10 to 90.degree. C.
[0013] Further, the present invention provides the adhesive sheet
as described above, wherein the adhesive sheet is an adhesive sheet
for attaching to a plasticized vinyl chloride resin article having
a center-line surface roughness Ra of 1.0 .mu.m or higher.
[0014] Furthermore, the present invention provides the adhesive
sheet as described above, wherein the plasticized vinyl chloride
resin article is an blood bag made of a plasticized vinyl chloride
resin.
PREFERRED EMBODIMENTS FOR CARRYING OUT THE INVENTION
[0015] The film substrate in the present invention includes films
or sheets of plastics of polyolefin resins such as polyethylene
resin and polypropylene; polyester resins such as polybutylene
terephthalate resin and polyethylene terephthalate resin; acetate
resins; ABS resins; polystyrene resins; vinyl chloride resins and
the like. Among them, films or sheets of vinyl chloride resins and
polyester resins are preferable.
[0016] The film substrate may be formed in either a single layer or
multiple layers having two or more layers. The film substrate can
be not oriented, or can be oriented into uniaxial direction or
biaxial direction such as longitudinal direction or cross
direction. The thickness of the film substrate is not limited, but
the thickness may usually be 10 to 250 .mu.m, and is preferably 25
to 200 .mu.m.
[0017] The flow direction breaking strength of the film substrate
is preferably 10 N/15 mm to 220 N/15 mm and the cross direction
breaking strength of the film substrate is preferably 10 N/15 mm to
220 N/15 mm. By controlling the breaking strength of the film
substrate in the above range, the breaking of the film substrate
becomes more difficult. Further the breaking strength of the film
substrate becomes smaller than the adhesive strength of the
heat-sensitive adhesive layer to the plasticized vinyl chloride
resin article, therefore, if the adhesive sheet is forced to be
peeled off from the plasticized vinyl chloride resin article
against the adhesive strength, the film substrate is broken before
the film substrate is peeled off from the plasticized vinyl
chloride resin article. Accordingly, it becomes difficult to
replace the adhesive sheet from the plasticized vinyl chloride
resin article for attaching to the other plasticized vinyl chloride
resin article intentionally. The breaking strength was measured
pursuant to JIS K7127.
[0018] The film substrate can be colored or colorless transparent.
A printing, a character printing or the like can be provided on the
surface or the backside surface of the film substrate. Therefore, a
heat-sensitive recording layer, a layer for receiving printing
image which can provide a heat transfer printing, an inkjet
printing, a laser printing or the like, a layer for improving
printability, an layer for adhering ink easily or the like can be
formed on the surface or the backside surface of the film
substrate.
[0019] Also, in order to improve the adhesion strength (keying
strength) of the film substrate to the heat-sensitive adhesive
layer, a primer treatment, a corona discharge treatment, or the
like can be provided on the backside surface of the film substrate
composing the heat-sensitive adhesive layer.
[0020] In the present invention, the heat-sensitive adhesive layer
is composed of a resin comprising a crystalline polyester resin as
a main component.
[0021] The crystalline polyester resin has a heat of melting
crystal of 5 to 50 J/g in measuring by a differential scanning
calorimeter. When the heat of melting crystal is low, the
crystalline polyester resin becomes nearly amorphous, the resin
strength becomes lower, the adhesive strength decreases, and also,
the blocking resistance is inferior. When the heat of melting
crystal is high, the crystallization rate becomes faster, the open
time becomes shorter, and the crystal shrinking becomes larger, so
that the adhesive strength is decreased. The heat of melting
crystal is preferably 10 to 45 J/g, and more preferably 15 to 40
J/g.
[0022] The crystalline polyester resin has a melting point of
preferably 50 to 200.degree. C., and more preferably 70 to
150.degree. C. The crystalline polyester resin has a glass
transition temperature of preferably -30 to 70.degree. C., and more
preferably -20 to 50.degree. C.
[0023] The content ratio of the crystalline polyester resin
comprised in the resin composing the heat-sensitive adhesive layer
is preferably 50 to 100 percent by mass, more preferably 60 to 100
percent by mass, furthermore preferably 70 to 100 percent by mass
and most preferably 80 to 100 percent by mass.
[0024] The resin composing the heat-sensitive adhesive layer can
contain the other resins other than the crystalline polyester
resin. The other resins include various resins, but preferably
amorphous polyester resins.
[0025] The amorphous polyester resin has excellent wettability and
excellent followability to the surface of the article when the
adhesive sheet is attached to the plasticized vinyl chloride resin
article. In particular, when the surface of the article is rough,
the amorphous polyester resin has excellent wettability and
excellent followability of the adhesive sheet to the surface of the
article.
[0026] The amorphous polyester resin has a glass transition
temperature of preferably 10 to 90.degree. C., and more preferably
30 to 80.degree. C. When the glass transition temperature of the
amorphous polyester resin is less than 10.degree. C., the blocking
resistance trends to decrease easily. When the glass transition
temperature of the amorphous polyester resin is more than
90.degree. C., it takes long time to melt, and therefore, there is
an instance that the heat sealing property becomes worse.
[0027] The content ratio of the amorphous polyester resin comprised
in the resin composing the heat-sensitive adhesive layer is
preferably 50 to 0 percent by mass, more preferably 40 to 0 percent
by mass, furthermore preferably 30 to 0 percent by mass and most
preferably 20 to 0 percent by mass. When the amorphous polyester
resin is comprised in the resin composing the heat-sensitive
adhesive layer, the lower limit value of the content is preferably
not less than 0.1 percent by mass, more preferably not less than
0.5 percent by mass, and most preferably not less than 1 percent by
mass.
[0028] The polyester resin as described above can be produced by
usually polymerizing a polyol and a polyhydric carboxylic acid.
[0029] The polyol includes diethylene glycol, dipropylene glycol,
polyether polyols such as triethylene glycol and polyethylene
glycol, polyester polyols, ethylene glycol, propylene glycol, 1,
4-butanediol, 1, 3-pentanediol, neopentyl glycol, 1, 6-hexanediol,
cyclohexanediol, 2, 2, 4-trimethyl-1,3-pentanediol, glycerol,
glycerol monoallyl ether, trimethylol ethane, trimethylol propane,
and pentaerythritol. The polyol can be utilized singly or in
combination of 2 or more members.
[0030] The polyhydric carboxylic acid includes malonic acid,
phthalic acid, terephthalic acid, isophthalic acid, tetrahydro
phathalic acid, methyl tetrahydro phthalic acid, hexahydro phthalic
acid, methyl hexahydro phthalic acid, succinic acid, glutaric acid,
hexachloro endomethylene tetrahydrophthalic acid, endomethylene
tetrahydrophthalic acid, endomethylene hexahydrophthalic acid,
adipic acid, sebasic acid, azelaic acid, dimmer acid,
decadicarboxylic acid, cycrohexane-dicarboxylic acid, trimellitic
acid, pyromellitic acid, trimesic acid, and cycropentane
dicarboxylic acid. The polyhydric carboxylic acid can be utilized
singly or in combination of 2 or more members.
[0031] The combination of the polyol and the polyhydric carboxylic
acid can be properly selected to produce the crystalline polyester
resin or the amorphous polyester resins and to control the glass
transition temperature to be in the range described above.
[0032] The polyester resin can be utilized singly or in combination
of 2 or more members.
[0033] The heat sensitive adhesive layer is preferably cured by
adding a crosslinking agent. By crosslinking the crosslinking
agent, the heat sensitive adhesive layer can have strong adhesive
strength, strong cohesive force and more excellent blocking
resistance. The crosslinking agent includes polyisocyanate
compounds, epoxy compounds, aluminium chelate compounds and
ethylene imine compounds. Preferable crosslinking agent is
polyisocyanate compounds. Most preferable crosslinking agent
includes aliphatic or alicyclic polyisocyanate compounds in view of
the weather resistance. The polyisocyanate compounds include
polyisocyanate compounds having two or more isocyanate groups per
one molecule, and, for example, various polyisocyanate compounds
such as di-isocyanate compounds, tri-isocyanate compounds,
tetra-isocyanate compounds, penta-isocyanate compounds and
hexa-isocyanate compounds.
[0034] Examples of the polyisocyanate compounds include aromatic
polyisocyanates such as tolylene diisocyanate, xylylene
di-isocyanate, diphenylmethane di-isocyanate, biphenyl
di-isocyanate, 3,3'-dimethyl-4,4'-biphenylene di-isocyanate,
methylene-bis(phenylisocyanate), isophorone di-isocyanate, and
alicyclic polyisocyantes such as hydrogenated tolylene
diisocyanate, hydrogenated xylylene di-isocyanate and hydrogenated
diphenylmethane di-isocyanate, and aliphatic polyisocyanates such
as 1,4-tetra-methylene di-isocyanate, hexamethylene diisocyanate
and 2,2,4-trimethylhexamethylene diisocyanate.
[0035] When crosslinking agent is used, a crosslinking promoting
agent is preferably added.
[0036] The crosslinking promoting agent includes, for example,
amine compounds such as triethylamine and tetramethylbutanediamine,
and metal compounds such as stannous chloride, dimethyl dichloro
tin, trimethyl tin hydroxide, di-n-butyl tin dilaurate, dibutyl tin
diacetate, dibutyl tin sulfide, ferric chloride, ferric
acetylacetate, cobalt naphthenate, bismuth nitrate, lead oleate and
amtimony trichloride.
[0037] When the crosslinking agent is used, the used polyester
resin has preferably a hydroxyl value of 1 or more mgKOH/g. The
upper limit of the hydroxyl value of the polyester resin can be
selected properly and is preferably not more than 50 mgKOH/g, and
more preferably not more than 20 mgKOH/g. The most preferable range
of the hydroxyl value of the polyester resin is 2 to 10 mgKOH/g.
Among the polyester resins, the crystalline polyester resin has
most preferably the hydroxyl value of the range described
above.
[0038] The adding amount of the crosslinking agente is preferably
0.01 to 10 parts by mass, and more preferably 0.1 to 5 parts by
mass to 100 parts by mass of the polyester resin.
[0039] Additionally, one or more additives can be contained in the
heat-sensitive adhesive layer, according to needs. The additives
include fillers, dyes, pigments, antioxidants and ultraviolet
absorbers. The fillers include inorganic fillers such as titanium
dioxide, silica, calcium carbonate, barium sulfate and talc, and
organic fillers such as starch. The antioxidants include anilide
antioxidants, phenol antioxidants, phosphite antioxidants, and
thioester antioxidants. The ultraviolet absorbers include
benzophenone ultraviolet absorbers and benzotriazole ultraviolet
absorbers.
[0040] The heat-sensitive adhesive layer can be formed by applying
a heat-sensitive adhesive on the backside surface of the film
substrate, which is a mixture prepared by mixing the components
described above, and optionally mixing a diluent additionally to
control a proper viscosity, and optionally drying and/or
crosslinking, or can be formed by applying the heat-sensitive
adhesive on a surface of a release base, optionally drying and/or
crosslinking, and then laminating the backside surface of the film
substrate on the surface of the applied layer.
[0041] The diluents contained in the heat-sensitive adhesive or
added later, include aromatic hydrocarbons such as benzene, toluene
and xylene; aliphatic hydrocarbons such as hexane, heptane, octane,
nonane and decane; ketones such as methyl ethyl ketone, diethyl
ketone and diisopropyl ketone. The formulating amount of the
diluent can be selected properly to control the demanded
viscosity.
[0042] The thickness of the heat-sensitive adhesive layer is not
limited particularly, but usually 5 to 40 .mu.m, and preferably 10
to 25 .mu.m.
[0043] In the present invention, a printing or a character printing
can be provided on the surface of the heat-sensitive adhesive
layer.
[0044] And, the surface of the heat-sensitive adhesive layer can be
covered with a release liner.
[0045] The release liner is made of a support base having release
property on at least one surface. The support base can have the
surface having release property obtained by applying a release
agent, or the surface without applying a release agent.
[0046] The support base of the release liner includes, for example,
papers, synthetic papers and plastic films. The papers include, for
example, glassine paper and polyethylene laminated paper. The
plastic films include, for example, films of plastics such as
polyolefine resin of polyethylene resin, polypropylene resin or the
like, polyester resin of polybutylene terephthalate resin,
polyethylene terephthalate resin or the like, acetate resin,
polystyrene resin and vinyl chloride resin. The proper examples of
the release liner having the surface without applying a release
agent, include polyolefin resin film such as polyethylene resin
film, polypropylene resin film and the like, and films obtained by
laminating the polyolefin resin film on the paper or the other
films.
[0047] The thickness of the support base of the release liner is
not limited particularly, and the thickness is generally 15 to 300
.mu.m.
[0048] The release agent used in the release liner includes a
silicone-based resin, an alkyd resin, a fluorine-based resin and a
long-chain alkyl based resin.
[0049] The thickness of the adhesive sheet laminated with the film
substrate, the heat-sensitive adhesive layer and the release liner,
is preferably a thickness which can introduce into a printer or the
like, and generally a level of about 50 to 300 .mu.m.
[0050] The adhesive sheet of the present invention can be a flat
sheet, or a sheet wound in a roll shape.
[0051] The adhesive sheet of the present invention can be used in
various uses for attaching the heat-sensitive adhesive layer. The
adhesive sheet is useful particularly when an adherend is an
article made of a plasticized vinyl chloride resin. The adhesive
sheet of the present invention does not cause lifting or peeling,
even if a sterilization treatment is conducted after attaching to a
blood bag made of a plasticized vinyl chloride resin. Therefore,
the adhesive sheet of the present invention is particularly useful
in the use as an indication label or a management label of the
blood bag. The adhesive sheet of the present invention can
particularly operate effectively when the adherend made of the
plasticized vinyl chloride resin has a rough surface. The
center-line surface roughness of the adherend made of the
plasticized vinyl chloride resin is preferably 1 .mu.m or more, and
more preferably 1.5 .mu.m or more.
[0052] The center-line surface roughness of the adherend made of
the plasticized vinyl chloride resin is not limited particularly,
but it is preferably not more than 20 .mu.m, and more preferably
not more than 10 .mu.m.
[0053] The adhesive sheet for attaching to the blood bag is printed
on the surface of the film substrate with the information such as a
blood type and collecting date and time of blood. The attaching of
the adhesive sheet to the blood bag is conducted before charging
the blood into the blood bag.
[0054] The attaching of the adhesive sheet to the adherend, is
generally conducted by superimposing the heat-sensitive adhesive
layer directly on the surface of the adherend and then heating and
pressing. The heating temperature is preferably 80 to 160.degree.
C. in general, more preferably 100 to 150.degree. C. and most
preferably 120 to 140.degree. C. The pressure for the pressing is
generally 0.5 to 10 kg/cm.sup.2. The time for the pressing is
preferably 0.1 to 5 seconds and more preferably 0.5 to 3
seconds.
[0055] The adhesive sheet of the present invention does not
decrease in the strength even after an autoclave treatment or a
storage at a low temperature, does not cause lifting or peeling,
has excellent adhesive property for the long time, and is excellent
in blocking resistance. The adhesive sheet of the present invention
is extremely excellent in practicability.
EXAMPLES
[0056] In the following, the present invention is explained in more
detail by Examples. Further, the present invention is not limited
at all by these Examples.
[0057] The adhesive strength measuring test in the Examples was
conducted according to the following methods.
[0058] (1) Adhesive Strength Measuring Test
[0059] On the surface having a center-line surface roughness Ra of
6.3 .mu.m of a blood bag made of a plasticized vinyl chloride
resin, a surface of a heat-sensitive adhesive layer of an adhesive
sheet was attached by heat sealing at a temperature of 130.degree.
C. for a pressing time of 2 seconds under a pressure of 3
kg/cm.sup.3 with a heat sealer (manufactured by TESTER SANGYO Co.
LTD., trade name "HEAT SEAL TESTER TP-701"). The adhesive sheets
attached to the blood bag were respectively peeled off at a pull
speed of 300 mm/min by a 180.degree. peeling method, at a condition
after 30 minutes from the heat sealing (Condition 1) and at a
condition after autoclave treatment for 40 minutes with a high
pressure sterilization machine (manufactured by HIRAYAMA
MANUFACTURING CORPORATION, trade name "AUTO HIGH PRESSURE
STERILIZATION MACHINE HA-24 TYPE") after 30 minutes from the heat
sealing (Condition 2). The peeled states of the adhesive sheet and
the blood bag in condition 1 or condition 2 were observed by
visual. The peeled states were evaluated on the basis of the
following standards.
.circleincircle.: The blood bag made of plasticized vinyl chloride
resin or the film substrate of the adhesive sheet was broken.
.largecircle.: A part of the blood bag made of plasticized vinyl
chloride resin or a part of the film substrate of the adhesive
sheet was broken. X: The blood bag made of plasticized vinyl
chloride resin or the film substrate of the adhesive sheet was not
broken, and the adhesive sheet was peeled off.
[0060] (2) Autoclave Applicability
[0061] On the surface having a center-line surface roughness Ra of
6.3 .mu.m of a blood bag made of a plasticized vinyl chloride
resin, a surface of a heat-sensitive adhesive layer of an adhesive
sheet was attached by heat sealing at a temperature of 130.degree.
C. for a pressing time of 2 seconds under a pressure of 3
kg/cm.sup.3 with a heat sealer (manufactured by TESTER SANGYO Co.
LTD., trade name "HEAT SEAL TESTER TP-701"). After 30 minutes from
the heat sealing, an autoclave treatment was conducted for 40
minutes with a high pressure sterilization treatment machine
(manufactured by HIRAYAMA MANUFACTURING CORPORATION, trade name
"AUTO HIGH PRESSURE STERILIZATION MACHINE"). Lifting or peeling of
the adhesive sheet was observed by visual. The results were
evaluated on the basis of the following standards.
.largecircle.: Lifting or peeling was not caused in the adhesive
sheet. X: Lifting or peeling was caused in the adhesive sheet.
[0062] (3) Blocking Test
[0063] The heat-sensitive adhesive layer of the adhesive sheet was
superposed on the backside surface of the heat-sensitive adhesive
layer of the adhesive sheet. The superposed adhesive sheet was left
for 120 hours in the environment of 60.degree. C. with application
of a load of 20 g/cm.sup.2. And then, the backside surface of the
adhesive sheet was observed by visual whether there is blocking or
not. The results were evaluated on the basis of the following
standards.
.circleincircle.: The adhesive sheet was peeled off without
resistance. .largecircle.: The adhesive sheet was peeled off with
making some noise. .DELTA.: The heat sealing agent or a part of the
film substrate was left on the backside surface of the
heat-sensitive adhesive layer of the adhesive sheet. X : The film
substrate was broken.
Example 1
[0064] A solution obtained by mixing 100 parts by mass (as solid
component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM", a heat of melting
crystal of 26.99 J/g measured by a differential scanning
calorimeter) and 100 parts by mass of a diluent which is toluene,
was applied on a backside surface (non-treatment surface) of a film
substrate composed of a polyester film sheet having a layer for
adhering ink easily on the surface (produced by TOYOBO CO., LTD.,
trade name "CRISPER K2311" , a thickness of 50 .mu.m, flow
direction breaking strength of 94 N/15 mm, cross direction breaking
strength of 118 N/15 mm) in an amount to form a heat-sensitive
adhesive layer having a dried thickness of 12 .mu.m and dried. And
then, on the surface of the formed heat-sensitive adhesive layer, a
release liner composed of a polyethylene terephthalate film having
a silicone resin layer on one surface (manufactured by LINTEC
Corporation, trade name "SP-PET38CL", a thickness of 38 .mu.m) was
laminated to make an adhesive sheet.
[0065] On the surface of the film substrate of the adhesive sheet,
blood information was printed. Next, the printed adhesive sheet was
cut in a label size and then the release liner was peeled off. The
obtained adhesive sheet was heat sealed at a temperature of
130.degree. C. for a pressing time of 2 seconds under a pressure of
3 kg/cm.sup.3 on the surface having a center-line surface roughness
Ra of 6.3 .mu.m of a blood bag made of a plasticized vinyl chloride
resin to attach. When the adhesive sheet was attached, peeling or
slipping was not observed.
[0066] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Example 2
[0067] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 100 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM") and 100 parts by
mass of a diluent which is toluene, was applied on a backside
surface (non-treatment surface) of the film substrate and was dried
to form a heat-sensitive adhesive layer.
[0068] The obtained adhesive sheet was heat sealed at a temperature
of 130.degree. C. for a pressing time of 2 seconds under a pressure
of 3 kg/cm.sup.3 on the surface having a center-line surface
roughness Ra of 2 .mu.m of a blood bag made of a plasticized vinyl
chloride resin to attach. When the adhesive sheet was attached,
peeling or moving was not observed.
[0069] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Example 3
[0070] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 90 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM"), 10 parts by mass
(as solid component) of an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") and 100 parts by mass of a diluent which is toluene, was
applied on a backside surface (non-treatment surface) of the film
substrate and was dried to form a heat-sensitive adhesive
layer.
[0071] The obtained adhesive sheet was heat sealed at a temperature
of 130.degree. C. for a pressing time of 2 seconds under a pressure
of 3 kg/cm.sup.3 on the surface having a center-line surface
roughness Ra of 2 .mu.m of a blood bag made of a plasticized vinyl
chloride resin to attach. When the adhesive sheet was attached,
peeling or moving was not observed.
[0072] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Example 4
[0073] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 60 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM"), 40 parts by mass
(as solid component) of an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") and 100 parts by mass of a diluent which is toluene, was
applied on a backside surface (non-treatment surface) of the film
substrate and was dried to form a heat-sensitive adhesive
layer.
[0074] The obtained adhesive sheet was heat sealed at a temperature
of 130.degree. C. for a pressing time of 2 seconds under a pressure
of 3 kg/cm.sup.3 on the surface having a center-line surface
roughness Ra of 2 .mu.m of a blood bag made of a plasticized vinyl
chloride resin to attach. When the adhesive sheet was attached,
peeling or moving was not observed.
[0075] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Example 5
[0076] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 90 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM"), 10 parts by mass
(as solid component) of an amorphous polyester resin having a glass
transition temperature of 40.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-219
S30TO") and 100 parts by mass of a diluent which is toluene, was
applied on a backside surface (non-treatment surface) of the film
substrate and was dried to form a heat-sensitive adhesive
layer.
[0077] The obtained adhesive sheet was heat sealed at a temperature
of 130.degree. C. for a pressing time of 2 seconds under a pressure
of 3 kg/cm.sup.3 on the surface having a center-line surface
roughness Ra of 2 .mu.m of a blood bag made of a plasticized vinyl
chloride resin to attach. When the adhesive sheet was attached,
peeling or moving was not observed.
[0078] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Example 6
[0079] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 100 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM", a hydroxyl value of
8 mgKOH/g), 0.5 parts by mass (as solid component) of a
crosslinking agent (aromatic polyisocyanate compound, manufactured
by TOYO INK MFG. Co. Ltd., trade name "BHS8515") and 100 parts by
mass of a diluent which is toluene, was applied on a backside
surface (non-treatment surface) of the film substrate and was dried
to form a heat-sensitive adhesive layer.
[0080] The obtained adhesive sheet was heat sealed at a temperature
of 130.degree. C. for a pressing time of 2 seconds under a pressure
of 3 kg/cm.sup.3 on the surface having a center-line surface
roughness Ra of 2 .mu.m of a blood bag made of a plasticized vinyl
chloride resin to attach. When the adhesive sheet was attached,
peeling or moving was not observed.
[0081] After the adhesive sheet was left for 3 months in the state,
the adhesive condition of the adhesive sheet was observed by
visual. Lifting or peeling was not observed. The adhesive strength
measuring test, the autoclave applicability and the blocking test
were conducted. The results are shown in Table 1.
Comparative Example 1
[0082] An adhesive sheet was prepared in the same manner as Example
1 except that an ethylene-vinyl acetate copolymer resin
(manufactured by TOYO-MORTON Co. Ltd., trade name "AD-1790-15") was
used instead of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C.
[0083] The obtained adhesive sheet was attached on the surface
having a center-line surface roughness Ra of 6.3 .mu.m of a blood
bag made of a plasticized vinyl chloride resin in the same manner
as Example 1.
[0084] The adhesive strength measuring test, the autoclave
applicability and the blocking test were conducted. The results are
shown in Table 1.
Comparative Example 2
[0085] An adhesive sheet was prepared in the same manner as Example
1 except that an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") was used instead of a crystalline polyester resin having a
glass transition temperature of 10.degree. C. and a melting point
of 110.degree. C.
[0086] The obtained adhesive sheet was attached on the surface
having a center-line surface roughness Ra of 6.3 .mu.m of a blood
bag made of a plasticized vinyl chloride resin in the same manner
as Example 1.
[0087] The adhesive strength measuring test, the autoclave
applicability and the blocking test were conducted. The results are
shown in Table 1.
Comparative Example 3
[0088] An adhesive sheet was prepared in the same manner as Example
1 except that an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") was used instead of a crystalline polyester resin having a
glass transition temperature of 10.degree. C. and a melting point
of 110.degree. C.
[0089] The obtained adhesive sheet was attached on the surface
having a center-line surface roughness Ra of 2 .mu.m of a blood bag
made of a plasticized vinyl chloride resin in the same manner as
Example 1.
[0090] The adhesive strength measuring test, the autoclave
applicability and the blocking test were conducted. The results are
shown in Table 1.
Comparative Example 4
[0091] An adhesive sheet was prepared in the same manner as Example
1 except that an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") was used instead of a crystalline polyester resin having a
glass transition temperature of 10.degree. C. and a melting point
of 110.degree. C.
[0092] The obtained adhesive sheet was attached on the surface
having a center-line surface roughness Ra of 0.8 .mu.m of a blood
bag made of a plasticized vinyl chloride resin in the same manner
as Example 1.
[0093] The adhesive strength measuring test, the autoclave
applicability and the blocking test were conducted. The results are
shown in Table 1.
[0094] Comparative Example 5
[0095] An adhesive sheet was prepared in the same manner as Example
1 except that a solution obtained by mixing 10 parts by mass (as
solid component) of a crystalline polyester resin having a glass
transition temperature of 10.degree. C. and a melting point of
110.degree. C. (manufactured by Nippon Synthetic Chemical Industry
Co. Ltd., trade name "POLYESTAR SP-180 S20TM"), 90 parts by mass
(as solid component) of an amorphous polyester resin having a glass
transition temperature of 65.degree. C. (manufactured by Nippon
Synthetic Chemical Industry Co. Ltd., trade name "POLYESTAR TP-235
S20TM") and 100 parts by mass of a diluent which is toluene, was
applied on a backside surface (non-treatment surface) of the film
substrate and was dried to form a heat-sensitive adhesive
layer.
[0096] The obtained adhesive sheet was attached on the surface
having a center-line surface roughness Ra of 6.3 .mu.m of a blood
bag made of a plasticized vinyl chloride resin in the same manner
as Example 1.
[0097] The adhesive strength measuring test, the autoclave
applicability and the blocking test were conducted. The results are
shown in Table 1.
TABLE-US-00001 TABLE 1 Adhesive property Condition Condition
Autoclrave Blocking 1 2 applicability test Example 1
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Example 2 .circleincircle. .circleincircle. .largecircle.
.largecircle. Example 3 .circleincircle. .circleincircle.
.largecircle. .largecircle. Example 4 .circleincircle.
.largecircle. .largecircle. .largecircle. Example 5
.circleincircle. .circleincircle. .largecircle. .largecircle.
Example 6 .circleincircle. .circleincircle. .largecircle.
.circleincircle. Comparative X X X .largecircle. Example 1
Comparative .largecircle. X X X Example 2 Comparative .largecircle.
X X X Example 3 Comparative .largecircle. .largecircle.
.largecircle. X Example 4 Comparative .largecircle. .largecircle.
.largecircle. .DELTA. Example 5
* * * * *