U.S. patent application number 12/047391 was filed with the patent office on 2009-01-15 for personal care kit having skin care compositions with a readily perceptible difference.
Invention is credited to Robert Bao Ha, Larry Richard Robinson, Paul Robert Tanner, Dean Arthur Zimmerman.
Application Number | 20090017080 12/047391 |
Document ID | / |
Family ID | 39596558 |
Filed Date | 2009-01-15 |
United States Patent
Application |
20090017080 |
Kind Code |
A1 |
Tanner; Paul Robert ; et
al. |
January 15, 2009 |
PERSONAL CARE KIT HAVING SKIN CARE COMPOSITIONS WITH A READILY
PERCEPTIBLE DIFFERENCE
Abstract
A personal care kit comprises a first series of unit-dose
packages containing a first skin care composition and a second
series of unit-doses packages containing a second skin care
composition, wherein the first skin care composition and the second
skin care composition exhibit a readily perceptible difference. The
readily perceptible difference may be a visible difference, a
tactile difference, or an olfactory difference. The first and/or
second skin care composition may comprise a skin care active. A
method for using the personal care kit is also disclosed.
Inventors: |
Tanner; Paul Robert;
(Lebanon, OH) ; Robinson; Larry Richard;
(Loveland, OH) ; Ha; Robert Bao; (Liberty, OH)
; Zimmerman; Dean Arthur; (West Chester, OH) |
Correspondence
Address: |
THE PROCTER & GAMBLE COMPANY;Global Legal Department - IP
Sycamore Building - 4th Floor, 299 East Sixth Street
CINCINNATI
OH
45202
US
|
Family ID: |
39596558 |
Appl. No.: |
12/047391 |
Filed: |
March 13, 2008 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
|
|
60918216 |
Mar 15, 2007 |
|
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Current U.S.
Class: |
424/401 |
Current CPC
Class: |
A61K 8/19 20130101; A61Q
19/08 20130101; A61K 2800/88 20130101; A61K 8/0254 20130101 |
Class at
Publication: |
424/401 |
International
Class: |
A61K 8/02 20060101
A61K008/02; A61Q 19/00 20060101 A61Q019/00 |
Claims
1. A personal care kit comprising: a) a first series of unit-dose
packages containing a first skin care composition, b) a second
series of unit-doses packages containing a second skin care
composition, wherein the first skin care composition and the second
skin care composition exhibit a readily perceptible difference.
2. The personal care kit of claim 1 wherein the perceptible
difference is a visible difference.
3. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition comprising at least
about 0.001% of colorant and the second skin care compositions
being substantially free of colorant.
4. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition comprising at least
about 1% of a platelet powder and the second skin care composition
being substantially free of a platelet powder.
5. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition comprising at least
0.3% of a powder having a refractive index of greater than about 2
and the second skin care composition being substantially free of a
powder having a refractive index of greater than about 2.
6. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition comprising at least
about 0.5% of a powder having a refractive index of less than about
1.8 and the second skin care composition being substantially free
of a powder having a refractive index of less than about 1.8.
7. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition exhibiting a percent
transmission of greater than 60% and the second skin care
composition exhibiting a percent transmission of less than 60%.
8. The personal care kit of claim 2 wherein the visible difference
is provided by the first skin care composition comprising at least
about 2% of a silicone elastomer and the second skin care
composition being substantially free of silicone elastomer.
9. The personal care kit of claim 1 wherein the perceptible
difference is a tactile difference.
10. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition having a viscosity
of less than 40,000 centipoise and the second skin care composition
having a viscosity of more than 40,000 centipoise.
11. The personal care kit of claim 10 wherein the first skin care
composition has a viscosity of less than about 30,000 centipoise
and the second skin care composition has a viscosity of more than
about 50,000 centipoise.
12. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition results in a
post-application skin temperature change of at least 1.degree. C.
and the second skin care composition results in a post-application
skin temperature change of no more than 0.25.degree. C.
13. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition comprising a
temperature sensate and the second skin care composition being
substantially free of a temperature sensate.
14. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition comprising a warming
temperature sensate and the second skin care composition comprising
a cooling temperature sensate.
15. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition comprising an
abrasive particulate material having an average particle size of
greater than about 100 .mu.m and the second skin care composition
being substantially free of an abrasive particulate material having
an average particle size of greater than about 100 .mu.m.
16. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition comprising greater
than 30% of one or more oils and the second skin care composition
comprising no more than 30% of one or more oils.
17. The personal care kit of claim 16 wherein the tactile
difference is provided by the first skin care composition
comprising greater than about 40% of one or more oils and the
second skin care composition comprising no more than about 20% of
one or more oils.
18. The personal care kit of claim 9 wherein the tactile difference
is provided by the first skin care composition comprising a first
carrier in the form of an aqueous continuous emulsion and the
second skin care composition comprising a second carrier in the
form of an oil continuous emulsion.
19. The personal care kit of claim 18 wherein the aqueous
continuous emulsion of the first carrier is a silicone-in-water
emulsion and the oil continuous emulsion of the second carrier is a
water-in-silicone emulsion.
20. The personal care kit of claim 1 wherein the perceptible
difference is an olfactory difference.
21. The personal care kit of claim 20 wherein the olfactory
difference is provided by the first skin care composition
comprising a fragrance and the second skin care composition being
substantially fragrance free.
22. The personal care kit of claim 20 wherein the olfactory
difference is provided by the first skin care composition
comprising a first fragrance and the second skin care composition
comprising a second fragrance different from the first
fragrance.
23. The personal care kit of claim 1 wherein the first skin care
composition comprises at least one skin care active which the
second skin care composition does not comprise.
24. The personal care kit of claim 23 wherein the skin care active
is selected from a group consisting of sunscreens, retinoids,
hydroxyacids, vitamins, peptides, sugar amines, oil control agents,
tanning actives, anti-acne actives, desquamation actives,
anti-cellulite actives, chelating agents, skin lightening agents,
flavonoids, protease inhibitors, non-vitamin antioxidants and
radical scavengers, hair growth regulators, anti-wrinkle actives,
anti-atrophy actives, minerals, phytosterols and/or plant hormones,
tyrosinase inhibitors, anti-inflammatory agents, N-acyl amino acid
compounds, antimicrobials, antifungals, or mixtures thereof.
25. The personal care kit of claim 1 wherein the first skin care
composition and the second skin care composition both comprise a
skin care active, wherein the first skin care composition and the
second skin care composition differ in the weight percent of the
skin care active.
26. The personal care kit of claim 1 wherein the first series of
unit-dose packages comprise a first use indicium and the second
series of unit-doses packages comprise a second use indicium.
27. The personal care kit of claim 1 wherein the first series of
unit-dose packages contain less than about 5 mL of the first skin
care composition and the second series of unit-dose packages
contain less than about 5 mL of the second skin care
composition.
28. The personal care kit of claim 1 wherein the first series of
unit-dose packages contain less than about 2 mL of the first skin
care composition and the second series of unit-dose packages
contain less than about 2 mL of the second skin care
composition.
29. A personal care kit comprising: a) a first series of unit-dose
packages having a first use marking, each unit-dose package
comprising less than about 5 mL of a first skin care composition,
said first skin care composition comprising a aqueous continuous
phase and at least one skin care active, b) a second series of
unit-doses packages having a second use marking, each unit-dose
package comprising less than about 5 mL of a second skin care
composition, said second skin care composition comprising a oily
continuous phase and at least one skin care active.
30. A method for treating the skin comprising the steps of a)
dispensing and applying a first skin care composition from a first
unit-dose package; b) repeating step a) for a plurality of times at
a first interval, c) dispensing and applying a second skin care
composition from a second unit-dose package, d) repeating step d)
at a second routine interval wherein step c) begins after the
plurality of times and wherein the first skin care composition and
the second skin care composition exhibit a readily perceptible
difference.
31. A method for treating the skin comprising the steps of a)
dispensing and applying a first skin care composition from a first
unit-dose package once a day for m number of days, b) dispensing
and applying a second skin care composition from a second unit-dose
package once a day for n number of days, wherein step b) begins
about 24 hours after the m.sup.th day and wherein the first skin
care composition and the second skin care composition exhibit a
readily perceptible difference.
32. The method of claim 31 wherein m is at least 7 and n is at
least 7.
Description
CROSS REFERENCE TO RELATED APPLICATION
[0001] This application claims the benefit under 35 USC 119(e) to
U.S. Application Ser. No. 60/918,216, filed Mar. 15, 2007.
FIELD OF THE INVENTION
[0002] The present invention relates to a personal care kit having
a first series of unit-dose packages containing a first skin care
composition and a second series of unit-doses packages containing a
second skin care composition. The first skin care composition and
the second skin care composition exhibit a readily perceptible
difference.
BACKGROUND OF THE INVENTION
[0003] Consumers are faced with an overwhelming number of skin care
compositions within the marketplace. These compositions may
comprise skin care actives that provide a benefit through
regulating and/or improving skin condition. There are numerous skin
care actives, as are well known in the art, directed to a variety
purposes such as addressing the sign of skin aging or treating
insult-affected skin and other keratinous tissue. While some skin
care actives exhibit acute benefits that are immediately
appreciable to a user, many skin care actives exhibit chronic
benefits that are realized after a period of time. Usually the
chronic benefit is achieved by routine application of the skin care
composition over several days, weeks, or months. Unfortunately,
many users do not adhere to a routine application of the skin care
composition that is necessary to achieve the chronic benefit. For
example, after a week of daily application of a skin care
composition, some users may become discouraged that a chronic
benefit is not visibly or tactily perceptible. Other users may
simply lose interest in regular application of the skin care
composition. This is particularly true if the skin care composition
is directed to regulating skin condition such that a user's skin is
maintained without degradation. In such a case, the user can not
appreciate that the skin care composition is providing a chronic
benefit since the maintenance benefit may only be appreciated by
discontinuing use and then suffering a degradation in skin
condition.
[0004] Another issue related to skin care compositions that exhibit
chronic benefits is the issue of dosing. Many skin care
compositions are provided to the user in a bulk package suitable
for several applications. Users often do not apply the idea dose.
By applying too little of the skin care composition, the chronic
effect may be delayed or may never materialize. The user may become
discouraged with the skin care composition even though the
composition is effective when dosed properly. Conversely, by
applying too much of the skin care composition, materialization of
the chronic effect is not accelerated. The user may become
discouraged with quantity and cost of skin care composition being
used even though the composition is beneficial and cost effect when
dosed properly. In both cases, incorrect dosing of skin care
composition from a bulk package can impact the chronic benefit
perceived by the user. Further complicating the use of bulk
packages is variable dosing. In some situations, it is necessary to
vary the dose of skin care composition. For example, the amount of
skin care composition may be gradually increased or decreased
during the course of a dosing regimen. User compliance to variable
dosing is poor when using a bulk package.
[0005] In light of the discussion provided above, there exists a
need in the personal care industry and, more specifically, the skin
care industry for an easy to use personal care kit comprising a
plurality of skin care compositions in unit-dose packaging to
address, at least in part, the issues of improper dosing. A need
also exists for the personal care kit to comprise a plurality of
skin care compositions that exhibit a readily perceptible
difference to address, at least in part, the issue surrounding what
may be a prolonged appearance of a chronic benefit or the lack of
appreciation of the chronic benefit.
SUMMARY OF THE INVENTION
[0006] In light of the needs presented above, the present invention
in one embodiment relates a personal care kit comprising a first
series of unit-dose packages containing a first skin care
composition and a second series of unit-doses packages containing a
second skin care composition, wherein the first skin care
composition and the second skin care composition exhibit a readily
perceptible difference. The readily perceptible difference may be a
visible difference, a tactile difference, or an olfactory
difference. The first and/or second skin care composition may
comprise a skin care active.
[0007] By way of further addressing the needs presented above, the
present invention in one embodiment relates to a method for
treating the skin comprising the steps of (a) dispensing and
applying a first skin care composition from a first unit-dose
package; (b) repeating step (a) for a plurality of times at a first
interval; (c) dispensing and applying a second skin care
composition from a second unit-dose package; (d) repeating step (c)
at a second routine interval; wherein step (c) begins after the
plurality of times. The application of the skin care composition
may occur daily for a number of days such as for 7 days.
BRIEF DESCRIPTION OF THE DRAWINGS
[0008] FIGS. 1A-F are suitable embodiments of unit-dose
packages.
[0009] FIG. 2 depicts a suitable personal care kit.
[0010] FIG. 3A is a top view of a suitable personal care kit.
[0011] FIG. 3B is a cross-sectional view taken through line A-A of
FIG. 3A.
DETAILED DESCRIPTION OF THE INVENTION
[0012] As used herein, the following terms shall have the meaning
specified thereafter. It should be recognized that capitalization
of the listed terms is predicated on grammar and may not be
continued throughout the remaining of the text.
[0013] "Series" refers to a plurality of packages (e.g.,
containers, vials, vessels, cans, cartons, canisters, tubes, or
like devices) containing the same skin care composition wherein the
plurality are used in succession and without intervening use of
another, different skin care composition, wherein both skin care
compositions are provided within a personal care kit.
[0014] "Applied" or "application", unless explicitly stated
otherwise, means to spread a composition onto keratinous tissue
with one or more fingers and/or an implement, as one would be
expected to apply a cream to the facial skin.
[0015] "Perceptible difference" refers to a difference between one
skin care composition and another skin care composition that is
perceptible to a person having normal sensory abilities (e.g.,
20/20 vision, normal hearing, unimpaired tactile sensation, etc.)
under standard conditions. For example, standard lighting
conditions are at least one of the following: natural illumination
as experienced outdoors during daylight hours, the illumination of
a standard 100 watt incandescent white light bulb at a distance of
2 meters, or as defined by CIE D65 standard illuminate lighting at
800 lux to a 1964 CIE standard observer.
[0016] "Readily perceptible difference" refers to a perceptible
difference that is perceptible before, during, or immediately after
(i.e., less than 5 minutes) application of the skin care
compositions.
[0017] "Post-application skin temperature change" refers to the
absolute value of the difference between the skin temperature
measured immediately before application of a skin care composition
and the skin temperature measured 1 minute after application of the
skin care composition. Prior to application, the skin care
composition is equilibrated to the pre-application skin
temperature.
[0018] "Personal care composition" means a composition suitable for
topical application on mammalian keratinous tissue.
[0019] "Dose" refers the amount of skin care composition to be used
during application.
[0020] "Unit-dose package" refers to a package (e.g., container,
vial, vessel, ampule, pouch, can, carton, canister, capsule, tube,
substrate, wipe, pad, cup, blister pack, or like devices)
containing a single dose of a skin care composition which is to be
completely dispensed and applied.
[0021] "Bulk package" refers to a package containing a plurality of
doses of a skin care composition.
[0022] "Skin care actives," or "actives," as used herein, means
compounds that, when applied to the skin, provide a benefit or
improvement to the skin. Skin care actives may be used for
regulating skin condition, improving skin condition, It is to be
understood that skin care actives are useful not only for
application to skin, but also to hair, nails, and other mammalian
keratinous tissue.
[0023] "Keratinous tissue" refers to keratin-containing layers
disposed as the outermost protective covering of mammals which
includes, but is not limited to, skin, hair, nails, cuticles,
etc.
[0024] "Regulating skin condition" means maintaining skin
appearance and/or feel with little to no degradation in appearance
and/or feel. "Improving skin condition" means affecting a positive
change in skin appearance and/or feel. The skin appearance and/or
feel benefit may be a chronic benefit and may include one or more
of the following: thickening of keratinous tissue (e.g., building
the epidermis and/or dermis and/or sub-dermal layers of the skin,
and where applicable the keratinous layers of the nail and hair
shaft, to reduce skin, hair, or nail atrophy); increasing the
convolution of the dermal-epidermal border (also known as the rete
ridges); preventing loss of skin or hair elasticity, for example,
due to loss, damage and/or inactivation of functional skin elastin,
resulting in such conditions as elastosis, sagging, loss of skin or
hair recoil from deformation; reduction in cellulite; change in
coloration to the skin, hair, or nails, for example, under-eye
circles, blotchiness (e.g., uneven red coloration due to, for
example, rosacea), sallowness, discoloration caused by
hyperpigmentation, maintaining/improving the signs of skin aging,
and maintaining/improving insult-affected keratinous tissue.
[0025] "Signs of skin aging," include, but are not limited to, all
outward visibly and tactilely perceptible manifestations, as well
as any macro- or micro-effects, due to keratinous tissue aging.
These signs may result from processes which include, but are not
limited to, the development of textural discontinuities such as
wrinkles and coarse deep wrinkles, fine lines, skin lines,
crevices, bumps, large pores, unevenness or roughness; loss of skin
elasticity; discoloration (including undereye circles);
blotchiness; sallowness; hyperpigmented skin regions such as age
spots and freckles; keratoses; abnormal differentiation;
hyperkeratinization; elastosis; collagen breakdown, and other
histological changes in the stratum corneum, dermis, epidermis,
vascular system (e.g., telangiectasia or spider vessels), and
underlying tissues (e.g., fat and/or muscle), especially those
proximate to the skin.
[0026] "Insult-affected keratinous tissue," means keratinous tissue
which exhibits discomfort, irritation, an unpleasant or irregular
appearance, and the like, for example after exposure to a physical
and/or chemical irritant. Non-limiting examples of insult-affected
keratinous tissue include burn (e.g., sunburns, windburn, chemical
or thermal burns); rashes (e.g., diaper rash, shaving rash and
allergen-induced rashes); discoloration (e.g., bleaching, staining,
hyperpigmentation); nicks and cuts (e.g., shaving insults); and
dry, chapped or rough skin (e.g., due to exposure to example wind,
cold and/or low humidity). Non-limiting examples of insults include
radiation, wind, low humidity, allergens, pollutants, chemical and
natural irritants, bodily fluids, bodily waste, excessive moisture,
bacteria, fungi, etc.
[0027] "Safe and effective amount" means an amount of a compound or
composition sufficient to induce a positive benefit but low enough
to avoid serious side effects (i.e., provides a reasonable benefit
to risk ratio within the judgment of a skilled artisan).
[0028] "Substantially free," when used in reference to a substance
that facilitates a readily perceptible difference, refers to an
amount of the substance within a skin care composition that is
undetectable to a person having normal sensory abilities.
Substantially free by definition includes 0% of a substance.
[0029] In all embodiments of the present invention, all percentages
are by weight of the total composition, unless specifically stated
otherwise. All ratios are weight ratios, unless specifically stated
otherwise. All ranges are inclusive and combinable; therefore,
every range given throughout this specification will include every
narrower range that falls within such broader range as if such
narrower ranges were all expressly written herein. The number of
significant digits conveys neither a limitation on the indicated
amounts nor on the accuracy of the measurements. Unless explicitly
stated otherwise, all measurements are understood to be made at
25.degree. C. and at ambient conditions, where "ambient conditions"
means conditions under about one atmosphere of pressure and at
about 50% relative humidity. All such weights as they pertain to
listed ingredients are based on the active level and do not include
carriers or by-products that may be included in commercially
available materials, unless otherwise specified.
I. Personal Care Kit
[0030] The personal care kit of the present invention may be used
for the care of keratinous tissue. The personal care kit of the
present invention may be used for the care of skin of the whole
body or the face. The personal care kit of the present invention
may be used for care of discrete spots of skin. The personal care
kit may regulate and/or improve skin condition. The personal care
kit may regulate and/or improve signs of skin aging or
insult-affect keratinous tissue.
[0031] The personal care kit comprises a first series of unit-dose
packages containing a first skin care composition and a second
series of unit-dose packages containing a second skin care
composition. All of the first series is applied and used prior to
application and use of the second series; conversely, in other
embodiments, all of the second series may be applied and used first
prior to the application and use of the first series. It is further
contemplated that the first and second skin care compositions may
be used in parallel (i.e., a repeating application regime of the
first skin care composition and the second skin care composition).
The first skin care composition and the second skin care
composition exhibit a readily perceptible difference.
[0032] The particular number of unit-dose packages comprising the
first skin care composition or the second skin care composition is
not limited. In certain embodiments, the kit comprises a plurality
of unit-dose packages comprising the first skin care composition
and a plurality of unit-dose packages comprising the second skin
care composition. In other embodiments, the kit may comprise 7, 14,
or 21 unit-dose packages comprising the first skin care composition
and 7, 14, or 21 unit-dose packages comprising the second skin care
composition.
[0033] The dosing interval of the first skin care composition and
the second skin care composition is not limited. The dosing
interval may be selected based on the composition of the skin care
composition and, if present, skin care active within in the
composition. Customary dosing intervals for topical application of
skin care composition include once daily (e.g., applied once each
day at approximately the same time) and twice daily (e.g., applied
twice each day at approximately the same time and at approximately
equal intervals). However, other dosing intervals are contemplated
(e.g., frequency of more or less than once per week). In one
embodiments, a first skin care composition from a first unit-dose
package is applied once a day for m number of says and then, after
all of the first unit-dose packages have been used, a second skin
care composition from a second unit-dose package is applied once a
day for n number of days.
[0034] The kit is not limited in construction or physical form. In
certain embodiments, the kit may be in the form of a consumer unit.
A "consumer unit" is a single entity for consumer sale that
contains the components of the kit. The consumer unit may comprise
several packages, boxes, or other like containers that are joined
to form a single entity (e.g., several smaller packages contained
within a larger container, several packages bound or adhered to for
a single entity, etc.). For example, the first series of unit-dose
packages containing a first skin care composition may be provided
in a first container, the second series of unit-dose packages
containing a second skin care composition may be provided in a
second container, and the first container and second container may
be joined to form the consumer unit.
[0035] A. Unit-Dose Package--As defined above, a unit-dose package
refers to a package containing a single dose of a skin care
composition which is to be completely dispensed and applied. The
particular form of the unit-dose package may be of any suitable
form such as, but not limited to, a container, vial, vessel,
ampule, pouch, sachet, can, carton, canister, capsule, tube,
substrate, wipe, pad, cup, blister pack, or like devices. In
certain embodiments, the unit-dose package may be gas-impermeable
and/or liquid-impermeable. In certain embodiments, the unit-dose
package is constructed to prevent inadvertent dispensation of the
skin care composition. FIG. 1A depicts one particular embodiment of
a unit-dose package (10) in the form of a tube (12) that has a
frangible seal (14) on one end and a crimped seal (16) on the
opposing end. In the aforementioned design, the frangible seal (14)
is twisted-off thereby enabling a user to dispense the composition
by squeezing on the tube. FIG. 1B depicts a unit-dose package (10)
in the form of an ampule (22) having a frangible tip (24). FIG. 1C
is another embodiment of a unit-dose package (10) in the form of a
vial (32) with a removable lid (34). FIG. 1D is another embodiment
of a unit-dose package (10) in the form of a sachet (42) formed
from two substrates that are perimeter-sealed (44) to form an inner
void (46). FIG. 1E is another embodiments of a unit-dose package
(10) in the form of a moisten wipe (52). The wipe (52) is shown as
being contained within a liquid impermeable pouch (54) with a
portion of the pouch removed to show the underlying wipe (52). In
other embodiments, the wipe (52) may be a dry wipe. Furthermore,
the wipe (52) may be container in various other overwraps or
containers. For example, a plurality of wipes (52) may be stored in
a jar or like container. Other suitable substrate-based unit-dose
packages are shown in U.S. Pat. No. 5,616,337 and in U.S.
Publication 2004/0109720. FIG. 1F depicts another embodiment of
unit-dose package (10) in the form of a dispensing applicator (62).
The dispensing applicator (62) comprises two substrates that are
perimeter-sealed (64) to form a reservoir (66). The reservoir (66)
opens to a substrate (68) joined to one end of the dispensing
applicator (62). The substrate (68) is placed in contact with the
skin to deliver the skin care composition. The substrate (68) may
be any suitable skin-friendly material such a nonwoven web, a woven
fabric, a foam, and the like. U.S. Pat. No. 6,902,335 provides
additional discussion of the dispensing applicator (62).
[0036] In another embodiment, the unit-dose package may be in the
form of a swab-type applicator such as disclosed in U.S. Pat. Nos.
3,958,571, 4,173,978, and 4,799,815. Other suitable unit-dose
packages are described in U.S. Pat. Nos. 4,257,838, 4,342,395,
4,871,091, 4,951,822, 4,979,630, 5,063,057, 5,270,054, 5,503,885,
and 5,535,885 and in U.S. Design Pat. Nos. 515,936, 505,861,
488,375, 467,336, 463,275, 446,445, 443,505, 442,078, 435,440,
425,617, 411,296, 392,184, 369,212, 362,390, 347,995, 331,009,
327,008, 324,333, 318,795, 296,869, and 288,061.
[0037] The prescribed amount of skin care composition provided in
the unit-dose package is not limited. The dose of skin care
composition contained in unit-dose package may depend on the target
area. For example, in certain embodiments, the unit-dose package
may be constructed to deliver a dose of about 30-25 mL for full
body application, about 5-1 mL for facial application, and less
than about 1 mL for spot treatment. However, a smaller or larger
dose may be delivered depending on the skin condition and
components of the skin care composition.
[0038] In one embodiment, there is a difference in the packaging
between said products. These differences may be in aesthetic for
example the color, shape or appearance of the packaging. For
example, in the tubes of the present invention it would be possible
to have a different heat seal in the end of the tube such as a
straight heat seal and a curved heat seal. The printing could also
be matte versus glossy. Furthermore the packaging could include a
number or other visual indicators that they are different including
graphics, printing, etc.
[0039] Within a series of unit-dose packages, the individual
unit-dose packages may be similar or different. Likewise, between
two or more series of unit-dose packages, the individual unit-dose
packages within the first series may be similar or different from
the individual unit-dose packages within the second series. In an
exemplary embodiment, the unit-dose packages of the first series
may be in the form of a container having an applicator such as
depicted in the aforementioned U.S. Pat. No. 6,902,335 and the
unit-dose packages of the second series may be in the form of a
tube such as depicted in the aforementioned U.S. Design Pat. No.
288,061. The unit-dose packages within the skin care kit of the
present invention may supplied separately or may be interconnected.
The unit-dose packages may be interconnected directly (i.e., one
unit-dose package is directly joined to another unit-dose package)
or indirectly (e.g., one unit-dose package is joined to a substrate
or housing that also joined one or more other unit-dose
packages).
[0040] In one embodiment of the personal care kit (200), as shown
in FIG. 2, the unit-dose packages (210) of the first series and the
second unit-dose packages (220) of the second series are housed in
a tray (230) have suitable recesses (232) to accept the unit-dose
packages (210, 220). The unit-dose packages (210) of the first
series and the second unit-dose packages (220) of the second series
may be arranged to facilitate compliance with the successive
application of the series.
[0041] In another embodiment the personal care kit (300), as shown
in FIGS. 3A-B, the unit-dose packages (310) of the first series are
joined to a first housing (312). The unit-dose packages (320) of
the second series are joined to a second housing (322). The first
housing (312) and second housing (322) may secure their respective
unit-dose packages (310, 320). The first housing (312) and second
housing (322) may be constructed to provide a recess into which the
respective unit-dose packages (310, 320) fit. The first housing
(312) and second housing (322) may prevent repositioning of the
respective unit-dose packages (310, 320) during normal shipping and
handling of the personal care kit (300). FIG. 3A shows a top-view
of the personal care kit (300). FIG. 3B shows a cross-sectional
view taken through sectional line A-A of FIG. 3A. FIG. 3B shows a
suitable arrangement of the unit-dose packages (310) of the first
series joined to the first housing (312) and unit-dose packages
(320) of the second series joined to the second housing (322). The
first and second housings (312, 322) may be disposed within tray
(330). The tray (330) may assist in maintaining the relative
position of the unit-dose packages (310, 320). The first and second
housings (312, 322) may be disposed such that the first housing
(312) is more readily accessible than the second housing (322) to a
user. As shown in FIG. 3B, the first housing (312) may be
positioned on top of the second housing (322). Such a positioning
facilities the successive use of the series. A user will most
likely use the unit-dose packages (310) of the first series and
then remove the first housing (312) thereby gaining access to the
unit-dose packages (320) of the second series. The first and second
housing (312, 322) may be discrete or integral.
[0042] In certain embodiments, the unit-dose packages of the first
series have a first indicium (410) and the unit-dose packages of
the second series have a second indicium (420) different from the
first indicium (as shown in FIGS. 2 and 3A-B). "Indicium" refers to
any type of visible identifying mark or property of the unit-dose
package. Suitable indicia include the shape, color, design, print,
graphics, text, numbers, and the like. In one embodiment, the first
series of unit-dose packages have a color different from the color
of the unit-dose packages in the second series. In another
embodiment, the first series of unit-dose packages may be printed
with a first use indicium and the second series of unit-dose
packages may be printed with a second use indicium. The first use
indicium and second use indicium are indicia that convey a sequence
such that the first use indicium precedes the second use indicium
within the sequence. Suitable first use and second use indicium
include numbers, and letters. In one embodiment as shown in FIGS. 2
and 3A-B, the first series of unit-dose packages may be printed
with a first use indicium (410) of the number "1" and the second
series of unit-dose packages may be printed with a second use
indicium (420) of the number "2".
[0043] B. Skin Care Compositions--The skin care compositions of the
present invention may comprise a dermatologically acceptable
carrier and, optionally, one or more skin care actives.
[0044] (i) Dermatologically Acceptable Carrier--The skin care
compositions of the present invention can also comprise a
dermatologically acceptable carrier ("carrier") for the
composition. In one embodiment, the carrier is present at a level
of from about 50% to about 100%, about 60% to about 99.9%, about
70% to about 98%, or, alternatively, from about 80% to about 95%,
by weight of the composition.
[0045] The carrier can be in a wide variety of forms. Non-limiting
examples include simple solutions (water or oil based), emulsions,
and solid forms (gels, sticks, flowable solids, amorphous
materials). In certain embodiments, the dermatologically acceptable
carrier is in the form of an emulsion. Emulsion may be generally
classified as having a continuous aqueous phase (e.g., oil-in-water
and water-in-oil-in-water) or a continuous oil phase (e.g.,
water-in-oil and oil-in-water-in-oil). The oil phase of the present
invention may comprise silicone oils, non-silicone oils such as
hydrocarbon oils, esters, ethers, and the like, and mixtures
thereof. For example, emulsion carriers can include, but are not
limited to, continuous water phase emulsions such as
silicone-in-water, oil-in-water, and water-in-oil-in-water
emulsion; and continuous oil phase emulsions such as water-in-oil
and water-in-silicone emulsions, and oil-in-water-in-silicone
emulsions.
[0046] The aqueous phase typically comprises water. However, in
other embodiments, the aqueous phase may comprise components other
than water (non-water components), including but not limited to
water-soluble moisturizing agents, conditioning agents,
anti-microbials, humectants and/or other water-soluble skin care
actives, to impart an increased benefit to the keratinous tissue.
In one embodiment, the non-water component of the composition
comprises a humectant such as glycerin and/or other polyols.
However, it should be recognized that the carrier may be
substantially (i.e., less than 1% water) or fully anhydrous.
[0047] A skilled artisan will select a suitable carrier to yield a
desired product form. Furthermore, a skilled artisan will select a
suitable carrier to for any given skin care active or other
component will distribute primarily into either the water or oil
phase, depending on the water solubility/dispensability of the
component in the composition. In one embodiment, oil-in-water
emulsions are especially preferred.
[0048] Emulsions may further comprise an emulsifier. The skin care
composition may comprise from about 0.1% to about 10% or about 0.2%
to about 5% of an emulsifier, based on the weight of the
composition. Emulsifiers may be nonionic, anionic or cationic.
Suitable emulsifiers are disclosed in, for example, U.S. Pat. No.
3,755,560, U.S. Pat. No. 4,421,769, and McCutcheon's Detergents and
Emulsifiers, North American Edition, pages 317-324 (1986). Suitable
emulsions may have a wide range of viscosities, depending on the
desired product form.
[0049] The carrier may further comprise a thickening agent as are
well known in the art to provide a skin care compositions yielding
a suitable viscosity and rheological character.
[0050] (ii) Skin Care Active--The skin care composition of the
present invention may comprise a safe and effective amount of one
or more skin care active ("active") useful for regulating and/or
improving skin condition. Suitable actives include, but are not
limited to, vitamins, peptides, sugar amines, sunscreens, oil
control agents, tanning actives, anti-acne actives, desquamation
actives, anti-cellulite actives, chelating agents, skin lightening
agents, flavonoids, protease inhibitors, non-vitamin antioxidants
and radical scavengers, hair growth regulators, anti-wrinkle
actives, anti-atrophy actives, minerals, phytosterols and/or plant
hormones, tyrosinase inhibitors, anti-inflammatory agents, N-acyl
amino acid compounds, antimicrobials, and antifungals. The skin
care composition may comprise of the
[0051] "Vitamins" means vitamins, pro-vitamins, and their salts,
isomers and derivatives. Non-limiting examples of suitable vitamins
include: vitamin B compounds (including B1 compounds, B2 compounds,
B3 compounds such as niacinamide, niacinnicotinic acid, tocopheryl
nicotinate, C1-C18 nicotinic acid esters, and nicotinyl alcohol; B5
compounds, such as panthenol or "pro-B5", pantothenic acid,
pantothenyl; B6 compounds, such as pyroxidine, pyridoxal,
pyridoxamine; carnitine, thiamine, riboflavin); vitamin A
compounds, and all natural and/or synthetic analogs of Vitamin A,
including retinoids, retinol, retinyl acetate, retinyl palmitate,
retinoic acid, retinaldehyde, retinyl propionate, carotenoids
(pro-vitamin A), and other compounds which possess the biological
activity of Vitamin A; vitamin D compounds; vitamin K compounds;
vitamin E compounds, or tocopherol, including tocopherol sorbate,
tocopherol acetate, other esters of tocopherol and tocopheryl
compounds; vitamin C compounds, including ascorbate, ascorbyl
esters of fatty acids, and ascorbic acid derivatives, for example,
ascorbyl phosphates such as magnesium ascorbyl phosphate and sodium
ascorbyl phosphate, ascorbyl glucoside, and ascorbyl sorbate; and
vitamin F compounds, such as saturated and/or unsaturated fatty
acids.
[0052] The compositions of the present invention may comprise one
or more peptides. Herein, "peptide" refers to peptides containing
ten or fewer amino acids, their derivatives, isomers, and complexes
with other species such as metal ions (for example, copper, zinc,
manganese, and magnesium). As used herein, peptide refers to both
naturally occurring and synthesized peptides. In one embodiment,
the peptides are di-, tri-, tetra-, penta-, and hexa-peptides,
their salts, isomers, derivatives, and mixtures thereof. Suitable
peptides include, but are not limited to, peptides derived from soy
proteins, carnosine, palmitoyl-lysine-threonine (pal-KT) and
palmitoyl-lysine-threonine-threonine-lysine-serine (pal-KTTKS,
available in a composition known as MATRIXYL.RTM.),
palmitoyl-glycine-glutamine-proline-arginine (pal-GQPR, available
in a composition known as RIGIN.RTM.), these three being available
from Sederma, France,
acetyl-glutamate-glutamate-methionine-glutamine-arginine-arginine
(Ac-EEMQRR; Argireline.RTM.), and Cu-histidine-glycine-glycine
(Cu-HGG, also known as IAMIN.RTM.).
[0053] The compositions of the present invention may comprise a
sugar amine, also known as amino sugars, and their salts, isomers,
tautomers and derivatives. Sugar amines can be synthetic or natural
in origin and can be used as pure compounds or as mixtures of
compounds (e.g., extracts from natural sources or mixtures of
synthetic materials). Sugar amine compounds useful in the present
invention include, for example, N-acetyl-glucosamine, and also
those described in PCT Publication WO 02/076423 and U.S. Pat. No.
6,159,485.
[0054] The compositions of the subject invention may comprise one
or more sunscreen actives (or sunscreen agents). Herein, suitable
sunscreen actives include oil-soluble sunscreens, insoluble
sunscreens, and water-soluble sunscreens. Non-limiting examples of
suitable oil-soluble sunscreens are disclosed in The Cosmetic,
Toiletry, and Fragrance Association's The International Cosmetic
Ingredient Dictionary and Handbook, 10.sup.th Ed., Gottschalck, T.
E. and McEwen, Jr., Eds. (2004), p. 2267 and pp. 2292-93 and
include benzophenone-3, bis-ethylhexyloxyphenol methoxyphenyl
triazine, butyl methoxydibenzoyl-methane, diethylamino
hydroxy-benzoyl hexyl benzoate, drometrizole trisiloxane,
ethylhexyl methoxy-cinnamate, ethylhexyl salicylate, ethylhexyl
triazone, octocrylene, homosalate, polysilicone-15, and derivatives
and mixtures thereof. Non-limiting examples of suitable insoluble
sunscreens include methylene bis-benzotriazolyl
tetramethylbutyl-phenol, titanium dioxide, zinc cerium oxide, zinc
oxide, and derivatives and mixtures thereof. Non-limiting examples
of suitable water-soluble sunscreens include phenylbenzimidazole
sulfonic acid (PBSA), terephthalylidene dicamphor sulfonic acid,
(Mexoryl.TM. SX), benzophenone-4, benzophenone-5, benzylidene
camphor sulfonic acid, cinnamidopropyl-trimonium chloride,
methoxycinnamido-propyl ethyldimonium chloride ether, disodium
bisethylphenyl triaminotriazine stilbenedisulfonate, disodium
distyrylbiphenyl disulfonate, disodium phenyl dibenzimidazole
tetrasulfonate, methoxycinnamido-propyl hydroxysultaine,
methoxycinnamido-propyl laurdimonium tosylate, PEG-25 PABA
(p-aminobenzoic acid), polyquaternium-59, TEA-salicylate, and
salts, derivatives and mixtures thereof.
[0055] The compositions of the present invention may comprise one
or more compounds for regulating the production of skin oil, or
sebum, and for improving the appearance of oily skin. Examples of
suitable oil control agents include salicylic acid, dehydroacetic
acid, benzoyl peroxide, vitamin B3 compounds (for example,
niacinamide or tocopheryl nicotinate), their isomers, esters, salts
and derivatives, and mixtures thereof.
[0056] The compositions of the present invention may comprise a
tanning active such as dihydroxyacetone, which is also known as DHA
or 1,3-dihydroxy-2-propanone.
[0057] The compositions of the present invention may comprise a
safe and effective amount of one or more anti-acne actives.
Examples of useful anti-acne actives include resorcinol, sulfur,
salicylic acid, erythromycin, zinc, etc. Suitable anti-acne actives
are described in further detail in U.S. Pat. No. 5,607,980.
[0058] The compositions of the present invention may comprise a
safe and effective amount of a desquamation system such as
sulfhydryl compounds and zwitterionic surfactants as described in
U.S. Pat. No. 5,681,852. Another suitable desquamation system
comprises salicylic acid and zwitterionic surfactants and is
described in U.S. Pat. No. 5,652,228.
[0059] The compositions of the present invention may comprise a
safe and effective amount of an anti-cellulite agent including, but
are not limited to, xanthine compounds (e.g., caffeine,
theophylline, theobromine, and aminophylline).
[0060] The compositions of the present invention may comprise a
safe and effective amount of a chelating agent as disclosed in U.S.
Pat. No. 5,487,884. A suitable chelator is furildioxime and
derivatives.
[0061] The compositions of the present invention may comprise a
skin lightening agent including kojic acid, arbutin, tranexamic
acid, ascorbic acid and derivatives (e.g., magnesium ascorbyl
phosphate or sodium ascorbyl phosphate or other salts of ascorbyl
phosphate), ascorbyl glucoside, undecylenoyl phenylalanine
(Sepiwhite.RTM. from SEPPIC), aloesin, Actiwhite.RTM. (Cognis), and
Emblica.RTM. (Rona).
[0062] The compositions of the present invention may comprise a
flavonoid. The flavonoid can be synthetic materials or obtained as
extracts from natural sources, which also further may be
derivatized. Examples of classes of suitable flavonoids are
disclosed in U.S. Pat. No. 6,235,773.
[0063] The compositions of the present invention may comprise
protease inhibitors including, but are not limited to, hexamidine
(including salts and derivates thereof), vanillin acetate, menthyl
anthranilate, soybean trypsin inhibitor, Bowman-Birk inhibitor, and
mixtures thereof.
[0064] The compositions of the present invention may other optional
components such as non-vitamin antioxidants and radical scavengers,
hair growth regulators, anti-wrinkle actives, anti-atrophy actives,
minerals, phytosterols and/or plant hormones, tyrosinase
inhibitors, anti-inflammatory agents, N-acyl amino acid compounds,
antimicrobial or antifungal actives, and other useful skin care
actives, which are described in further detail in U.S. application
publication No. US2006/0275237A1 and US2004/0175347A1.
[0065] C. Readily Perceptible Difference--The personal care kit of
the present invention comprises a first series of unit-dose
packages containing a first skin care composition and a second
series of unit-dose packages containing a second skin care
composition wherein the first skin care composition and the second
skin care composition exhibit a readily perceptible difference. A
readily perceptible difference may be any difference between the
first skin care composition and the second skin care composition
that is perceptible to a person having normal sensory abilities
before, during, or immediately after (i.e., less than 5 minutes)
application of the skin care compositions. The readily perceptible
difference may be appreciable before application such as by visual
inspection of the skin care compositions with the unit-dose
packages. The readily perceptible difference may be appreciable
during application such as when the skin care composition is
dispensed on a user's fingers or area of skin targeted for
application. The readily perceptible difference may be appreciable
immediately after application of the skin care composition to the
area of skin targeted for application. In certain embodiments, the
readily perceptible difference is a tactile difference, a visible
difference, an olfactory difference, or any combination thereof.
The following readily perceptible differences represent suitable
embodiments of the present invention; however, the present
invention further contemplates any combination of two or more of
the following readily perceptible differences.
[0066] (i) Tactile Differences--The personal care kit of the
present invention comprises a first series of unit-dose packages
containing a first skin care composition and a second series of
unit-dose packages containing a second skin care composition
wherein the first skin care composition and the second skin care
composition exhibit a readily perceptible tactile difference. The
tactile difference may be any difference between the first skin
care composition and the second skin care composition that is
appreciable by the sense of touch (including pressure, hardness,
temperature, smoothness, greasiness, etc.). Exemplary tactile
differences are provided below.
[0067] (a) Viscosity--The first skin care composition may have a
higher or lower viscosity than the second skin care composition.
The resulting tactile difference is of one composition feeling thin
and the other composition feeling thick. In certain embodiments,
the two skin care compositions differ by at least about 5,000
centipoise (cP), 10,000 cP, or, alternatively, 20,000 cP. In one
embodiment, the first skin care composition exhibits a viscosity of
less than 40,000 cP and the second skin care composition exhibits a
viscosity of more than 40,000 cP. In another embodiment, the first
skin care composition exhibits a viscosity of less than 30,000 cP
and the second skin care composition exhibits a viscosity of more
than 50,000 cP.
[0068] (b) Skin Temperature--The first and second skin care
compositions may exhibit a tactile difference via a
post-application skin temperature change. In one embodiment, the
first skin care composition results in a post-application skin
temperature change of at least about 1.degree. C., about 2.degree.
C., or, alternatively, about 5.degree. C.; whereas the second skin
care composition results in a post-application skin temperature
change of less than about 0.25.degree. C. or about 0.10.degree. C.
or no change.
[0069] In other embodiments, the first skin care composition may
exhibit a post-application skin temperature increase of at least
about 1.degree. C., about 2.degree. C., or, alternatively, about
5.degree. C. and the second skin care composition may exhibit a
post-application skin temperature decrease of at least about
1.degree. C., about 2.degree. C., or, alternatively, about
5.degree. C.
[0070] Skin temperatures are measured using a high precision
hand-held infrared thermographic scanner such as the DermaTemp
DT-1001 available from Exergen Corp., Watertown, Mass. The skin
temperature measurements may be performed on any two symmetrically
opposing (i.e., sinister and dexter) skin surfaces ("sample site").
For example, the skin temperatures may be measured on the left and
right temple, cheek, forearm, shoulder, etc. A 1 inch by 1 inch
sample site is delineated (e.g., indelible ink or medical tape) on
the left and right skin surface. A pre-application skin temperature
is recorded for the left and right sample sites approximately 5
minutes prior to application of the skin care compositions. A dose
of the first skin care composition is applied to one sample site
and the second skin care composition is applied to the other sample
site. The skin care compositions are equilibrated to a temperature
of 75.degree. F. prior to application. One minute after
application, a post-application skin temperature is recorded for
the left and right sample sites. The post-application skin
temperature change is calculated by taking the absolute value of
the difference of the post-application skin temperature and the
pre-application skin temperature (i.e., |post-pre|). However, a
post-application skin temperature increase and post-application
skin temperature decrease are calculated by as the difference
between the post-application skin temperature and the
pre-application skin temperature (i.e., post-pre). The skin care
compositions may comprise about 5% to about 60% of metal chlorides
(e.g., calcium chloride, magnesium chloride, aluminum chloride,
ferric chloride), metal sulfates (e.g., calcium sulfate, magnesium
sulfate, aluminum sulfate, ferric sulfate), dry alum, calcium
oxide, and other as described in U.S. Publication 2004/0022823,
which may provide a post-application temperature change.
[0071] (c) Sensates--The skin care compositions may exhibit a
tactile difference through the use of warming sensates or cooling
senates. Sensates provide the sensation of heating or cooling to a
user, but may or may not yield a change in skin temperature. The
sensation may be instantaneous or may be delayed, but, generally,
is appreciable within 5 minutes of application of the skin care
composition.
[0072] Suitable warming sensates include vanillyl alcohol
derivatives including of vanillyl alcohol n-butyl ether, vanillyl
alcohol npropyl ether, vanillyl alcohol isopropyl ether, vanillyl
alcohol isobutyl ether, vanillyl alcohol n-amino ether, vanillyl
alcohol isoamyl ether, vanillyl alcohol n-hexyl ether, vanillyl
alcohol methyl ether and vanillyl alcohol ethyl ether; and
phosphate derivatives comprising the aforementioned vanillyl
alcohol derivatives such as vanillyl alcohol isoamyl ether
monophosphate, vanillyl alcohol n-butyl ether monophosphate,
vanillyl alcohol n-hexyl ether monophosphate. Other suitable
warming sensates include ethyl alcohol, niacin, jambu, nicotinic
acid, zingerone, vanillyl alcohol n-butyl ether, vanillyl alcohol
n-propyl ether, vanillyl alcohol isopropyl ether, vanillyl alcohol
isobutyl ether, vanillyl alcohol n-amino ether, vanillyl alcohol
isoamyl ether, vanillyl alcohol n-hexyl ether, vanillyl alcohol
methyl ether, vanillyl alcohol ethyl ether, gingerol, methyl
salicylate, shogaol paradol, zingerone, capsaicin,
dihydrocapsaicin, nordihydrocapsaicin, homocapsaicin,
homodihydrocapsaicin, ethanol, tincture capsicum, oleoresin ginger
alcohol extraction, eucalyptus oil, capsaicin, cinnamic aldehyde,
chloroform, ether, iso-Amyl alcohol, benzyl alcohol, allyl
isothiocyanate, ethyl acetate, glycerine, limonene, menthol,
4-hydroxy-4-methyl-cyclohexen-2-one-1, and mixtures thereof.
Further suitable warming sensates include fluid extracts,
hydro-alcohol extracts, essential oils, oleoresins, concretes or
distillates of mustard seed, ginger, horseradish, chillies,
jalapeno, pepper, capsicum, clove, cassia, and mixtures thereof.
Any mixture of the aforementioned warming sensates may also be
used.
[0073] Suitable cooling sensates include menthol, isopulegole,
3-(1-menthoxy)propan-1,2-diol, p-menthan-3,8-diol,
6-isopropyl-9-methyl-1,4-dioxaspiro-(4,5)-decane-2-methanol,
menthyl succinate, alkaline earth salts of menthyl succinate,
trimethyl cyclohexanol, N-ethyl-2-isopropyl-5-methylcyclohexane
carboxamide and other carboxamides as described in U.S. Pat. Nos.
4,136,163 and 4,230,688, 3-(1-menthoxy)-2-methyl-propan-1,2-diol,
mint oil, peppermint oil, wintergreen, menthone, menthone glycerin
ketal and other glycerol ketals described in U.S. Pat. No.
5,266,592, menthyl lactate,
2-(5'-methyl-2-(methylethyl)cyclohexyloxy)ethan-1-ol,
3-(5'-methyl-2'-(methylethyl)cyclohexyloxy)propan-1-ol,
4-(5'-methyl-2'-(methyl ethyl)cyclohexyloxy)butan-1-ol, and
spearmint. Other cooling sensates include p-menth-3-yl n-butyl
sulphoxide, n-butyl 1-isobutylcyclohexyl sulphoxide, n-hexyl
1-isobutylcyclohexyl sulphoxide, n-butyl 1-isoamylcyclohexyl
sulphoxide and n-hexyl 1,2-diethylcyclohexyl sulphoxide, and other
cyclic sulphoxides and sulphones as described in U.S. Pat. No.
4,032,661.
[0074] The skin care compositions may comprise from about 0.001% to
about 25% of one or more warming sensates or cooling sensates. In
one embodiment of the present invention, the first skin care
composition may comprise one or more warming sensates or one or
more cooling sensates and the second skin care composition is
substantially free of a warming sensate or cooling sensate. In
another embodiment of the present invention, the first skin care
composition may comprise one or more warming sensates and the
second skin care composition comprises one or more cooling
sensates.
[0075] (d) Abrasives--The skin care compositions may exhibit a
tactile difference through the use of particulate material having a
prescribed average particle size. The resulting tactile difference
is of one composition feeling abrasive or gritty and the other
composition feeling smooth. In a suitable embodiment, the first
skin care composition comprises an abrasive particulate material
having an average particle size of greater than about 100 .mu.m and
the second skin care composition is substantially free of an
abrasive particulate material having an average particle size of
greater than about 100 .mu.m. In other embodiments, the first skin
care composition comprises an abrasive particulate material having
an average particle size of greater than about 150 .mu.m, 200
.mu.m, or 250 .mu.m and the second skin care composition is
substantially free of an abrasive particulate material having an
average particle size of greater than about 100 .mu.m. In certain
embodiments, the skin care composition may comprise from about 0.1%
to about 20% of the abrasive particulate material that provides the
abrasive sensation.
[0076] Particulate materials useful herein include but are not
limited to bismuth oxychloride, sericite, mica, mica treated with
barium sulfate or other materials, zeolite, kaolin, silica, boron
nitride, lauroyl lysine, polyamide (e.g., nylon-12 and Orgasol.TM.
2002D Nat C05 available from Atofina), polyolefins including
polyethylene (e.g., Microthene.TM. line available from Equistar and
PFL (500-850 .mu.m), PFM (250-500 .mu.m), and PFS (100-250 .mu.m)
colored scrubbing beads from Kobo) and polypropylene, talc,
styrene, polystyrene (e.g., Dynospheres.TM. available from Dyno
Particles), ethylene/acrylic acid copolymer, sericite, aluminum
oxide, silicone resin, barium sulfate, calcium carbonate, cellulose
acetate, polytetrafluoroethylene (PTFE), polyacrylates (e.g.,
ethylene acrylate copolymer, sold under the name FloBead.TM. EA209
available from Kobo), polymethyl methacrylate (e.g., Micropearl.TM.
M 100 available from Seppic), starch, modified starches such as
aluminum starch octenyl succinate, silk, glass, fibers, ground
seeds, pumice, and mixtures thereof.
[0077] (e) Oil Content--The first skin care composition may
comprise a higher or lower oil content than that of the second skin
care composition. The resulting tactile difference is of one
composition feeling oily or greasy compared to the other
composition. In one embodiment, the first skin care composition has
an oil content of at least 30% and the second skin care content has
an oil content of less than 30%. In other embodiments, the first
skin care composition may have an oil content of at least 40%, 50%,
or 60% and the second skin care content has an oil content of less
than 25%, 20%, or 15%. The oil content is weight percentage, based
on the total weight of the composition, of all silicone oils and
non-silicone oils such as hydrocarbon oils, esters, and ethers
within the composition.
[0078] (f) Carrier--As discussed above, the skin care compositions
of the present invention may comprise a carrier. The first skin
care composition may comprise a first carrier and the second skin
care composition may comprise a second carrier wherein the first
and second carriers provide a readily perceptible tactile
difference. For example, the first skin care composition may
comprise a first carrier in the form of a continuous aqueous phase
emulsion and the second skin care composition may comprise a second
carrier in the form of a continuous oil phase emulsion. The
resulting tactile difference is that the first skin care
composition may feel less oily or greasy compared to the other
composition. In one embodiment, the first skin care composition
comprises a first carrier in the form of a silicone-in-water
emulsion and the second skin care composition comprises a second
carrier in the form of a water-in-silicone emulsion.
[0079] (g) Tightening--The skin care compositions may provide a
tightening sensation of the skin of a user. The tightening
sensation may be provided by suitable firming agents. In a suitable
embodiment, the first skin care composition comprises a firming
agent and the second skin care composition is substantially free of
a firming agent. The skin care composition may comprise a
sufficient quantity of the firming agent to yield the tightening
effect. In certain embodiments, the firming agents may be present
in concentrations ranging from about 0.01% to about 40%, from about
0.1% to about 10%, or, alternatively, from about 1% to about 5% of
the skin care composition.
[0080] Suitable firming agents include hydrolyzed proteins,
partially-hydrolyzed proteins, and mixtures thereof. These proteins
may be chemically modified with quaternary groups, fatty groups,
fatty alkyl quaternary groups, silicone groups, or may be a protein
copolymer. The source of the protein is not limited. Plant derived
proteins include soya proteins, wheat proteins, almond protein,
potato protein, oat proteins, pea proteins, sun flower proteins,
corn proteins, cottonseed proteins, peanut proteins, and wheat germ
protein. Other non-limiting examples include compounds containing
hydrolyzed vegetable protein (and) hydrolyzed vegetable starch such
as CROPEPTIDE W, hydrolyzed vegetable protein polysiloxane
copolymers such as CRODASONE W, and hydrolyzed vegetable protein
polyvinylpyrrolidone copolymers such as Hydrotriticum PVP; all
available from Croda, Inc., Edison, N.J. Animal derived proteins
include milk proteins, such as .beta.-lactoglobulin, casein, or
whey; serum proteins, such as horse serum; placental proteins;
albumen; amylase; collagen; crystalline; cytochrome C; elastin;
fibronectin; gelatin; gliadin; keratin; lipase; and serum albumin.
Other suitable firming agents include polyurethane-14 and
AMP-Acrylates copolymer mixture (such as the DynamX line from
National Starch & Chemical Company, Bridgewater, N.J.), sodium
polystyrene sulfonate (such as the Flexan line from National
Starch), modified corn starch (such as the Amaze line from National
Starch), polyimide-1 (such as AquaflexXL-30 from International
Specialty Products, Wayne, N.J.), and
vinylpyrrolidone/acrylates/lauryl methacrylate copolymer (such as
Styleze 2000 from International Specialty Products).
[0081] (ii) Visible Differences--The personal care kit of the
present invention comprises a first series of unit-dose packages
containing a first skin care composition and a second series of
unit-dose packages containing a second skin care composition
wherein the first skin care composition and the second skin care
composition exhibit a readily perceptible visible difference. The
tactile difference may be any difference between the first skin
care composition and the second skin care composition that is
appreciable by the sense of sight (including color, shape,
translucency, gloss, etc.). Exemplary tactile differences are
provided below.
[0082] (a) Colorants--The first skin care composition may exhibit a
color different than that of the second skin care composition. In
one embodiment, the first skin care composition may comprise one or
more colorants and the second skin care composition is
substantially free of a colorant. The skin care composition may
comprise a sufficient quantity of the colorant to yield the
tightening effect. The present skin care composition from about
0.001% to about 25%, from about 0.01% to about 20%, or,
alternatively, from about 0.1%% to about 15% of a colorant. In
certain embodiments, the skin care composition is substantially
free of a colorant when comprising less than 0.001%, less than
about 0.0001%, or, alternatively, less than about 0.00001% of a
colorant.
[0083] Suitable colorants may include inorganic or organic pigments
and powders. Organic pigments can include natural colorants and
synthetic monomeric and polymeric colorants. Organic pigments
include various aromatic types such as azo, indigoid,
triphenylmethane, anthraquinone, and xanthine dyes which are
designated as D&C and FD&C blues, browns, greens, oranges,
reds, yellows, etc. Organic pigments may consist of insoluble
metallic salts of certified color additives, referred to as the
Lakes. Inorganic pigments include iron oxides, ferric ammonium
ferrocyanide, manganese violet, ultramarines, chromium, chromium
hydroxide colors, and mixtures thereof. The pigments may be coated
with one or more ingredients that cause the pigments to be
hydrophobic. Suitable coating materials that will render the
pigments more lipophilic in nature include silicones, lecithin,
amino acids, phospholipids, inorganic and organic oils,
polyethylene, and other polymeric materials. Suitable silicone
treated pigments as disclosed in U.S. Pat. No. 5,143,722. Inorganic
white or uncolored pigments include TiO2, ZnO, or ZrO2, which are
commercially available from a number of sources. Other suitable
colorants are identified in U.S. Pat. No. 7,166,279.
[0084] (b) Percent Transmission--The skin care compositions may be
opaque (i.e., turbid) or translucent. The presence of colorants,
insoluble particles, gas bubbles, large internal phase domains, and
the like can affect the turbidity/translucency of a skin care
composition. Opacity and translucency may be quantitatively
determined by the percent transmission. Skin care compositions
yielding a percent transmission of greater than or equal to 60% are
considered translucent. Skin care composition yielding a percent
transmission of less than 60%, 55%, 50%, 40%, or, alternatively,
30% are considered opaque. In one embodiment, the first skin care
comprising is translucent and the second skin care composition is
opaque.
[0085] Percent transmission involves measuring the transmission of
light through a collagen film to which the skin care composition
has been applied, relative to a control film. The methodology
requires a light source sufficiently powerful for sample
illumination, a camera and video frame grabber for capturing the
image of the sample on the collagen surface and a computer with
video imaging software for data analysis and for viewing on a video
monitor. Suitable image capture and analysis software includes
Optimas 5.2 from Optimas Corp., Washington (refer to Image Analysis
Software guide Volume I), the software and guide being incorporated
herein by reference.
[0086] Using a collagen film (such as IMS #1192 or equivalent
available from IMS Inc., Milford, Conn.) mounted in a suitable
holder, apply 40 microliters (using a Microman M50 pipette) of
product and spread evenly by hand on the film surface using 10
finger rotations. Optionally, the sample is mounted on a Zeiss
SV-11 microscope (or equivalent) equipped with a 1.times. lens (the
microscope is useful for enlarging the image which the camera is
capturing; the effective magnification of this system is about 5
microns/pixel). A mounting template can optionally be employed to
aid in repositioning the sample for multiple measurements. The
SV-11 should be set up so that maximum light is being transmitted
to the camera (e.g., a Sony 760-MD CCD 3 Camera). To insure proper
positioning and a clear image, the equipment is set in the
following manner. Camera controls are set so that the Gamma and
Linear matrix switches are off. The camera control box settings are
further defined as follows: Gain=0, White/Black balance on auto,
iris- auto, mode-camera, detail-12 o'clock position, phase-0
degrees, SC-3 o'clock position, H-12 o'clock position, Color temp
-3200K, shutter off. The camera should be allowed to warm up for 15
minutes before adjusting white and black balance. Press the button
labeled "white" to adjust the white balance, and adjust black
balance by pulling the black adjustment rod and pushing the button
that says black. Computer cables are connected to the RGB I and
Composite Sync.ports on the camera. The microscope Iris is set to
completely open and a frosted glass plate is positioned in the
microscope base for a uniformly lit field. A clear glass plate may
optionally be used to adjust the sample height. Open the Optimas
5.2 program on the computer. Use a sample cup which is partially
covered with black tape in the light path to adjust gain and offset
(brightness). The reflecting mirror at the base of the microscope
is set for maximum reflection into the microscope. The mean of the
light source should be 245 to 254.5. The STD Deviation should be
less than 3. If the mean is out of specifications check the light
bulb alignment and mirror adjustment.
[0087] For the control, an untreated piece of collagen film (such
as IMS #1192 available from IMS Inc., Milford, Conn.), is mounted
on a sample cup which is placed on the microscope such that the
film lies in the center of the light path. The film is focused and
light transmission through the film is measured using the image
capture and analysis software. Multiple measurements are taken from
separate areas of the sample, repositioning and refocusing the film
for each measurement (seven or more measurements are taken). The
histogram mean and standard deviation are determined using the
image capture and analysis software.
[0088] For measuring light transmission by the test product, a
piece of collagen film is first pre-hydrated with distilled water
to insure flexibility. 40 microliters of test product is then
dispensed on the film (e.g., using a Microman M50 pipette or
equivalent), and spread evenly over its surface to produce an even
film covering the surface of the collagen (generally by lightly
spreading the material by applying 10 rotations of the finger,
wearing a clean, latex finger cot, to the material). After waiting
for a period of 5 minutes, the sample is mounted on the microscope
base. Light transmission measurements through the film and product
are then taken in the manner described for the control. Least
significant differences can be performed on the data using
Fischer's LSD method.
[0089] The coverage index and % transmission are calculated as
follows:
Coverage Index = Control Mean - Test Product Mean Control Mean
.times. 100 ##EQU00001## Percent Transmission = 100 - Coverage
Index ##EQU00001.2##
[0090] (c) Matting Effect--A skin care composition can provide a
matting effect (e.g., non-shiny) to the skin. The matting effect
may help hide imperfections such as large pores, fine lines and
wrinkles, and uneven skin tone while maintaining the natural
appearance of the skin (e.g., without unacceptable skin whitening
or discoloration). In one embodiment, the first skin care provides
a matting effect and the second skin care composition does not.
[0091] The matting effect may be provided through the use of a
requisite amount of silicone elastomer. In one embodiment, the
first skin care composition comprises greater than about 1% of a
silicone elastomer (on a solids basis as measured without carriers
or other solvents) and the second skin care composition is
substantially free of silicone elastomer. In other embodiments, the
first skin care composition may comprise greater than about 2%, 3%,
or, alternatively, 5% of a silicone elastomer. In certain
embodiments, the second skin care composition may comprises less
than about 0.1%, about 0.01%, or, alternatively, about 0.001% of a
silicone elastomer.
[0092] Suitable silicone elastomers include crosslinked
organopolysiloxane (or siloxane) elastomers, as described in U.S.
patent publication 2003/0049212A1. The silicone elastomers may be
emulsifying (e.g., having at least one polyoxyalkylene or
polyglycerin moiety) or non-emulsifying silicone elastomers (e.g.,
essentially free of polyoxyalkylene or polyglycerin moieties).
[0093] Suitable non-emulsifying silicone elastomers include the
CTFA (Cosmetic, Toiletry, and Fragrance Association International
Cosmetic Ingredient Dictionary and Handbook, 11.sup.th ed.)
designated dimethicone/vinyl dimethicone crosspolymers such as
supplied by Dow Corning.TM. (DC 9506), General Electric.TM. (SFE
839), Shin Etsu.TM. (KSG 15 and 16), and Grant Industries (GRANSIL
RPS-NA) and dimethicone/phenyl vinyl dimethicone crosspolymer such
as KSG 18 available from Shin Etsu.TM.. Other exemplary silicone
elastomers include the CTFA designated dimethicone crosspolymers
including Dow Corning.TM. (DC 9040, DC 9041, DC 9045).
[0094] Suitable emulsifying silicone elastomers include CTFA
designated dimethicone/PEG-10 crosspolymers such as KSG 24;
dimethicone/PEG-10 crosspolymers such as KSG 21 and KSG 210;
PEG-15/lauryl dimethicone crosspolymers such as KSG 31, KSG 32, KSG
33, KSG 310, KSG 320, KSG 330; PEG-15/lauryl dimethicone
crosspolymers and PEG-10/lauryl dimethicone crosspolymers such as
KSG 34 and KSG 340; dimethicone/polyglycerine-3 crosspolymers such
as KSG-710; and lauryl dimethicone/polyglycerine-3 crosspolymers
such as KSG 810, KSG 820, KSG 830, and KSG 840. All KSG materials
are available from Shin Etsu.TM..
[0095] The matting effect may be provided through the use of a
requisite amount of matting particles. In one embodiment, the first
skin care composition comprises greater than about 3% of a matting
particle and the second skin care composition is substantially free
of silicone elastomer. In other embodiments, the first skin care
composition may comprise greater than about 5%, about 10%, or,
alternatively, about 15% of the matting particle. In certain
embodiments, the second skin care composition may comprises less
than about 1%, about 0.1%, or, alternatively, about 0.01% of the
matting particles.
[0096] Matting particles have a refractive index of less than about
1.7. In other embodiments, the matting particles have a refractive
index from about 1.3 to about 1.6 as this range closely matches the
refractive index of skin. The matting particles may have an average
particle size of from about 0.1 to about 40 .mu.m. The average
particle size is measured when the particulate material is in the
neat form (i.e., in the essentially pure, powder form prior to
combination with a carrier). Refractive index can be determined by
conventional methods. The matting particles may have a
substantially spherical shape or a non-platelet shape (i.e., no one
dimension of the particle is at least 5-times smaller than the
other two dimensions).
[0097] Suitable organic matting particles include those made of
polymethylsilsesquioxane (e.g., Tospearl.RTM. 145 from GE Toshiba
Silicone Co., Ltd., which has a median particle size of about 4.5
.mu.m), polyamide (e.g., Orgasol.RTM. 2002 D NAT COS available from
Elf Atochem SA), polythene, polyacrylonitrile, polyacrylic acid,
polymethacrylic acid, polystyrene, polytetrafluoroethylene (PTFE)
and poly(vinylidene chloride). Copolymers derived from monomers of
the aforementioned materials can also be used (e.g., EA-209.RTM.
from Kobo Products, Inc., which is an ethylene/acrylic acid
copolymer having a median particle size of about 10 .mu.m).
Suitable inorganic matting particles include silica and boron
nitride.
[0098] (d) Luminescent Effect--A skin care composition can provide
a shine, glow, or a luminescent-effect. In one embodiment, the
first skin care provides the shine, glow, or a luminescent-effect
and the second skin care composition does not.
[0099] In one embodiment, the luminescent effect may be provided by
a skin care composition having a requisite percentage of
non-volatile oils. "Non-volatile," as used herein, means a material
that exhibit a vapor pressure of no more than about 0.2 mm Hg at
25.degree. C. at one atmosphere and/or a material that has a
boiling point at one atmosphere of at least about 300.degree. C. In
one embodiment, the first skin care composition comprises greater
than 10% of non-volatile oils and the second skin care composition
comprises less than 10% of non-volatile oils. In other embodiments,
the first skin care composition may comprise greater than about
15%, about 20%, or, alternatively, about 25% of non-volatile oils
and the second skin care composition comprises less than about 5%,
about 1%, or, alternatively, about 0.1% of non-volatile oils.
[0100] Suitable non-volatile, polar oils include, but are not
limited to, silicone oils, hydrocarbon oils; fatty alcohols, fatty
acids, esters of mono and dibasic carboxylic acids with mono and
polyhydric alcohols, polyoxyethylenes, polyoxypropylenes,
polyoxyethylene and/or polyoxypropylene ethers of fatty alcohols,
and mixtures thereof. Suitable non-volatile, non-polar oils
include, but are not limited to, non-volatile polysiloxanes,
paraffinic hydrocarbon oils, and mixtures thereof. Suitable
polysiloxanes include polyalkylsiloxanes, polyarylsiloxanes,
polyalkylarylsiloxanes, poly-ethersiloxane copolymers, and mixtures
thereof. Exemplary polysiloxanes include Viscasil.TM. series
(General Electric), Dow Corning 200 series (Dow Corning Corp.), SF
1075 methyl-phenyl fluid (General Electric), and 556 Cosmetic Grade
Fluid (Dow Corning Corp.). Suitable non-volatile paraffinic
hydrocarbon oils are described in U.S. Pat. No. 5,019,375 and in
U.S. Publication No. 2003/0049212A1 and include mineral oils and
branched-chain hydrocarbons such as Permethyl.TM. 102A, 103A and
104A (Permethyl Corporation), and Ethylflo.TM. 364 (Ethyl
Corp.).
[0101] The luminescent effect may be provided by a skin care
composition comprising platelet particles. The skin care
composition may comprise a sufficient quantity of the platelet
particles to yield the luminescent effect. In certain embodiments,
the first skin care composition comprises at least about 2% of
platelet particles and the second skin care composition is
substantially free of platelet particle. In other embodiments, the
first skin care composition may comprise at least about 5% of
platelet particles. In one embodiment, second skin care composition
comprises less than about 0.5%, 0.1%, or, alternatively, 0.01% of
platelet particles.
[0102] Platelet particles are particles having one dimension that
is at much smaller than in the other two dimensions. In certain
embodiments, platelet particles have one dimension at least 5-times
smaller than the other two dimensions and have a mean particle size
of at least about 5 .mu.m. The platelet shape allows the particle
to provide specular reflection. Specular reflection refers to the
phenomena where an incident beam of light is reflected at the equal
and opposite angle to the angle of incidence. Platelets can for
example be made of natural or synthetic mica, silica, alumina,
glass, boron nitride, and bismuth oxychloride. As well these
platelets can be coated with one or more layers of other
ingredients, such as metal oxides (e.g., tin oxide, titanium
dioxide, iron oxides), silica, and organic materials such as
various silicones, soaps, etc. These coating may function to alter
the optical properties of the material such as titanium dioxide
coated micas that produce colored interference effects. The
coatings may alter the polarity (e.g., hydrophilicity or
hydrophobicity) of the particles. Further discussion of platelet
particles is provided in U.S. Publication No. US2004/0234565A1.
[0103] (iii) Olfactory Differences--The personal care kit of the
present invention comprises a first series of unit-dose packages
containing a first skin care composition and a second series of
unit-dose packages containing a second skin care composition
wherein the first skin care composition and the second skin care
composition exhibit a readily perceptible olfactory difference. The
olfactory difference may be any difference between the first skin
care composition and the second skin care composition that is
appreciable by the sense of smell. In one suitable embodiment, the
first skin care composition comprises a first fragrance and the
second skin care composition is substantially fragrance free. In
another embodiment, the first skin care composition comprises a
first fragrance and the second skin care composition comprises a
second fragrance different from the first.
[0104] D. Other Secondary Differences--While the present invention
is directed, in part, to a personal care kit comprising a first
skin care composition and a second skin care composition exhibiting
a readily perceptible difference, other secondary differences may
exist between the first and second skin care composition. In some
embodiments, these secondary differences may be chronic differences
that would not be readily appreciable to a user but may become
appreciable over time. In other embodiments, the secondary
differences may not become appreciable to a user.
[0105] In certain embodiments, the secondary difference may be a
difference in the skin actives present within the skin care
compositions. For example, a personal care kit may comprise a first
skin care composition comprising a safe and effective amount (e.g.,
from about 1% to about 20%) of a sunscreen active and a second skin
care composition substantially free of a sunscreen active. In
another example, a personal care kit may comprise a first skin care
composition comprising a skin active that may irritate the skin
such as by having greater than about 0.05% of a retinoid and/or
greater than 1% of a hydroxyacid and a second skin care composition
substantially free of the skin active irritant.
[0106] In certain embodiments, the secondary difference may be a
difference in the percent composition of a skin care active between
skin care compositions. For example, a personal care kit may
comprise a first skin care composition comprising a first weight
percent of a skin active (e.g., 2% niacinamide) and a second skin
care composition comprising a second weight percent (e.g., 1% or 4%
niacinamide) of the skin care active, wherein the second weight
percent is higher or lower than the first weight percent.
[0107] In certain embodiments, the secondary difference may be a
difference in a device that is utilized during application. For
example, a personal care kit may comprise a first series of
unit-dose packages containing a first skin care composition that is
applied with a first device and a second series of unit-doses
packages containing a second skin care composition that is applied
by hand or by a second device different from the first device.
Suitable devices include microdermabrasion devices such as the
Neutrogena Advanced Solutions At Home Microdermabrasion System.
EXAMPLES
[0108] The following formulations are non-limiting examples of
suitable skin care compositions that provide one or more of the
above mentioned readily perceptible differences. Where applicable,
ingredients are given in CTFA name. The skin care compositions are
not specifically identified as a first or second skin care
composition since a skilled artisan will readily recognize that
various combinations of the Examples exist and may be used in the
kit of the present invention. While particular embodiments of the
subject invention have been described, it will be obvious to those
skilled in the art that various changes and modifications to the
subject invention can be made without departing from the spirit and
scope of the invention. The Examples may be slightly modified by
omitting key components that provide for the readily perceptible
difference (e.g., Example 5 contains colorants FD&C Red 40 and
Blue 1 which could be omitted to yield a colorant free examples).
Specifically, one or more of components listed in boldface may be
omitted to yield alternate examples.
TABLE-US-00001 (values are weight %) Ex. 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5
Ex. 6 Ex. 7 Ex. 8 Ex. 9 Ex. 10 PHASE A DC-9040 *1 5.10 13.5 50.7
DC-9045 *2 15 32.75 14.0 14.0 PEG-4 q.s to 100 Dimethicone 4.10 6
5.2 5.2 Polymethylsilsesquioxane *3 4.10 7.5 0.5 0.5 Polyethylene
beads *4 2.0 2.0 Cyclomethicone 11.40 23.5 15 10.0 1.05 1.05
KSG-210 *5 5.40 2.5 KSG-310 *6 20.0 Polyethylene wax *7 2.05
DC-2503 Cosmetic Wax *8 3.77 1.5 Abil EM97 *9 0.45 0.45 KF 6017 *10
0.375 Cetyl Ricinoleate 0.25 KTZ Fine TiO.sub.2 coated Mica *11
1.00 Dow Corning 1503 *12 3 3.5 3.5 Octisalate 4.0 Homosalate 4.0
Octocrylene 1.5 Avobenzene 2.0 Isopropyl Lauroylsarcosinate 7.5
Tospearl 145A *13 10 Prestige Fire Red 11S2 *14 0.1 Microthene
FN-510 *15 9 10.0 10.0 Petrolatum 0.5 Isohexadecane 3.0 3.0
Isopropyl Isostearate 1.0 1.0 Stearic Acid 0.4 0.4 Cetearyl
Glucoside 0.2 0.5 0.2 Cetyl Alcohol 1.0 1.3 1.0 Stearyl Alcohol
20.0 Magnesium Sulfate Anhydrous 3.0 PEG/PEG-300/55 Copolymer 2.0
Tego Care CP *16 1.78 Econol TM-22 *17 0.80 Distearyldimonium
chloride 0.25 Hydroxypropylcellulose Petrolatum 0.5 0.15 Fragrance
0.10 0.2 PHASE B Glycerin 10.00 10.00 11 10 10.0 2.0 10.0 2.0
Panthenol 0.5 1.00 0.7 1.0 1.0 1.0 Pentylene Glycol 3.00 Propylene
Glycol 1.00 1.0 1.0 1.0 Butylene Glycol 1.00 1.0 1.0 1.0 Tocopherol
Acetate 0.50 0.2 0.5 0.5 0.5 0.5 0.5 N-Acetyl Glucosamine 0.50 2.0
Hexamidine Diisethanoate *18 0.10 Niacinamide 5.00 4.00 5.00 5 5.0
2.5 5.0 2.5 Methylparaben 0.20 0.10 0.1 Ethylparaben 0.05 0.10 0.1
0.1 0.1 Benzyl Alcohol 0.25 0.50 0.4 0.4 0.4 0.1 Propyl Paraben
0.10 0.1 0.1 Disodium EDTA 0.10 0.05 0.1 0.1 0.1 Polysorbate 20 0.6
0.8 0.8 Glydant Plus Liquid *19 0.3 Laureth-4 0.2 0.2 0.2 Sucrose
Polycottonseedate 0.5 Allantoin 0.1 0.2 0.2 Prodew 400 *20
GLW75CAP-MP *21 0.35 0.35 Hydrolyzed wheat protein 2.0 Menthol 0.5
Vanillyl alcohol isoamyl ether 0.05 monophosphate Sodium Chloride
0.50 FD&C Red No. 40 .00025 FD&C Blue 1 .00011 Water q.s to
q.s to q.s to q.s to q.s to q.s to q.s to q.s to 100 100 100 100
100 100 100 100 Thickener Sepigel 305 *22 1.6 1.5 1.5 1.5 1.5 *1
12.5% Dimethicone Crosspolymer in Cyclopentasiloxane. Available
from Dow Corning. *2 Dimethicone Crosspolymer in
Cyclopentasiloxane. Available from Dow Corning. *3 E.g., Tospearl
145A or Tospearl 2000. Available from GE Toshiba Silicone *4 PFM
(250-500 .mu.m) colored beads from Kobo. *5 25% Dimethicone
PEG-10/15 Crosspolymer in Dimethicone. Available from Shin-Etsu *6
PEG-15/Lauryl Dimethicone Crosspolymer in Mineral Oil from
Shin-Etsu. *7 Jeenate 3H polyethylene wax. Available from Jeen *8
Stearyl Dimethicone. Available from Dow Corning. *9
Bis-PEG/PPG-14/14 Dimethicone. Available from Degussa *10 PEG-10
Dimethicone. Available from Shin-Etsu. *11 Hydrophobically modified
TiO.sub.2 coated Mica. Available from Kobo. *12
Dimethicone/Dimethiconol blend from Dow Corning. *13
Polymethylsilsesquioxane from General Electric. *14 Mica and iron
oxides from Eckart. *15 Polyethylene powder available from
Equistar. *16 Dioleoylethyl hydroxyethylmonium methosulfate mixture
available from Degussa Care & Surface Specialties, Hopewell,
VA. *17 Behenyltrimethylammonium chloride in carrier available from
Sanyo Performance Chemicals, JP. *18 Hexamidine diisethionate,
availabile from Laboratoires Serobiologiques. *19 DMDM Hydrantoin
and Iodopropynyl Butylcarbamate blend available from Lonza, Inc.
*20 Available from Ajinomoto U.S.A., Inc., Paramus NJ. *21
TiO.sub.2 with water, glycerine, polyacrylate, and methylparaben
available from Kobo Products. *22 Polyacrylamide, C13-14
Isoparaffin, and Laureth-7 blend from Seppic.
[0109] For example 1, combine the ingredients of Phase A in a
suitable container. In a separate suitable container, combine the
ingredients of Phase B. Heat each phase to 75-80.degree. C. while
mixing each phase using a suitable mixer (e.g., Anchor blade,
propeller blade) until each reaches temperature and is homogenous.
Slowly add Phase B to Phase A while continuing to mix Phase A.
Continue mixing until batch is uniform. Homogenize product with
Ultra-Turrax homogenizer (IKA, Inc) or equivalent and pour product
into suitable containers at 75-80.degree. C. Store the containers
at room temperature without disturbing for at least 12 hours.
[0110] For examples 2 and 5, in a suitable container, combine the
ingredients of Phase A and mix with a suitable mixer until
homogenous. In a separate container, combine the ingredients of
Phase B and mix until homogenous. Slowly add Phase B to Phase A
while continuing to mix Phase A. Continue mixing until batch is
uniform. Homogenize product with Ultra-Turrax homogenizer (IKA,
Inc) or equivalent and pour product into suitable containers.
[0111] For examples 3, 6-8, and 10, in a suitable vessel, the water
phase ingredients are combined and mixed until uniform; the water
phase may be warmed to dissolve all ingredients. In a separate
suitable container, the silicone/oil phase ingredients are combined
and mixed until uniform; the silicone/oil phase may be warmed to
dissolve all ingredients. Half the thickener and then the
silicone/oil phase is added to the water phase and the resulting
emulsion is milled (e.g., with a Tekmar T-25). The remainder of the
thickener and then the remaining ingredients are then added to the
emulsion while stirring. Once the composition is uniform, the
product is poured into suitable containers.
[0112] For examples 4 and 9, in a suitable vessel, the ingredients
are combined and mixed until uniform; the composition may be warmed
to dissolve all ingredients. Once the composition is uniform, the
product is poured into suitable containers.
[0113] A suitable unit-dose package for all of the examples may be
a unidose plastic tube with tear-open tamper-proof closure
available from CEBAL Tubes Europe.
[0114] The dimensions and values disclosed herein are not to be
understood as being strictly limited to the exact numerical values
recited. Instead, unless otherwise specified, each such dimension
is intended to mean both the recited value and a functionally
equivalent range surrounding that value. For example, a dimension
disclosed as "40 mm" is intended to mean "about 40 mm."
[0115] All documents cited in the Detailed Description of the
Invention are, in relevant part, incorporated herein by reference;
the citation of any document is not to be construed as an admission
that it is prior art with respect to the present invention. To the
extent that any meaning or definition of a term in this document
conflicts with any meaning or definition of the same term in a
document incorporated by reference, the meaning or definition
assigned to that term in this document shall govern.
[0116] While particular embodiments of the present invention have
been illustrated and described, it would be obvious to those
skilled in the art that various other changes and modifications can
be made without departing from the spirit and scope of the
invention. It is therefore intended to cover in the appended claims
all such changes and modifications that are within the scope of
this invention.
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