U.S. patent application number 11/144038 was filed with the patent office on 2006-12-07 for microstructured water having altered boiling point.
Invention is credited to David Bagley.
Application Number | 20060273282 11/144038 |
Document ID | / |
Family ID | 38325207 |
Filed Date | 2006-12-07 |
United States Patent
Application |
20060273282 |
Kind Code |
A1 |
Bagley; David |
December 7, 2006 |
Microstructured water having altered boiling point
Abstract
A composition includes microstructured water having a boiling
point higher than the boiling point of double distilled water. The
composition may include dissolved oxygen. The dissolved oxygen may
be present in an amount greater than 20 ppm. The microstructured
water may have a cluster size of 6-8 molecules, and may have a
cluster factor of about at least 30. The composition may include at
least one member selected from the group consisting of vitamins,
plant extracts, animal extracts, pharmaceutically active agents,
flavorants and colorants.
Inventors: |
Bagley; David; (Angel Fire,
NM) |
Correspondence
Address: |
FLESHNER & KIM, LLP
P.O. BOX 221200
CHANTILLY
VA
20153
US
|
Family ID: |
38325207 |
Appl. No.: |
11/144038 |
Filed: |
June 3, 2005 |
Current U.S.
Class: |
252/1 |
Current CPC
Class: |
C02F 2201/483 20130101;
C02F 2103/026 20130101; B01F 13/0006 20130101; C01B 13/10 20130101;
C02F 1/481 20130101; C02F 1/001 20130101; C02F 2301/024 20130101;
C02F 1/78 20130101; B01F 2003/04879 20130101; C01B 13/0229
20130101; C02F 1/444 20130101; B01F 5/0057 20130101; C02F 1/005
20130101; C02F 1/48 20130101; C02F 1/283 20130101; Y10S 261/39
20130101; C01B 13/02 20130101; B01F 3/0446 20130101; C02F 1/68
20130101; C02F 2301/026 20130101; C02F 1/32 20130101; C02F
2001/46195 20130101; C02F 1/727 20130101 |
Class at
Publication: |
252/001 |
International
Class: |
A23J 7/00 20060101
A23J007/00 |
Claims
1. A composition comprising microstructured water having a boiling
point higher than the boiling point of double distilled water.
2. The composition according to claim 1, wherein said composition
comprises dissolved oxygen.
3. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of 20 ppm to 150 ppm.
4. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 40 ppm.
5. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 60 ppm.
6. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 80 ppm.
7. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 100 ppm.
8. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 120 ppm.
9. The composition according to claim 2, wherein said dissolved
oxygen is present in an amount of greater than about 140 ppm.
10. The composition according to claim 1, wherein said
microstructured water has a cluster size of 6-8 molecules.
11. The composition according to claim 1, wherein said
microstructured water has a cluster factor of at least 150.
12. The composition according to claim 11, wherein said
microstructured water has a cluster factor of at least 200.
13. The composition according to claim 11, wherein said
microstructured water has a cluster factor of at least 30.
14. The composition according to claim 11, wherein said
microstructured water has a cluster factor of about 351.
15. The composition according to claim 1, wherein said composition
comprises at least one member selected from the group consisting of
vitamins, plant extracts, animal extracts, pharmaceutically active
agents, flavorants and colorants.
Description
BACKGROUND OF THE INVENTION
[0001] 1. Field of the Invention
[0002] This invention is directed to a composition that includes
microstructured water having a boiling point higher than the
boiling point of double distilled water.
[0003] 2. Background of the Related Art
[0004] Water supplies are becoming polluted at an alarming rate and
the aquifers that haven't been contaminated are now under duress.
Pristine aquifers are disappearing as demand for good, clean,
drinkable water increases. Water has been taken for granted for the
last seventy five years, and because so-called clean potable water
has been so easily and readily available from our kitchen tap, the
importance of water and water conservation has been lost to the
masses. Several of our larger cities and many smaller ones cannot
pass clean water tests. More and more chemicals are added to
municipal water supplies to enable these water supplies to pass
`safe` levels for consumption. Adequate chemical levels are
consistently being increased to accommodate the higher chemical
levels found in municipal water supplies. Mining, farming, and
industrial wastes have formed an intricate overlap of contaminants
that in most cases cannot be cleaned out of water supplies
sufficiently enough to make the water safe to bathe in, much less
drink.
[0005] Water treatment facilities inadvertently add pollutants to
their water at the same time it is being `purified`. Chlorine
reacts with organic substances in the water to form trihalomethanes
(THM's), a known group of carcinogens. In 1975, an EPA survey of
eighty cities` water supplies was the first official alarm that
there was a definite and serious problem. One particular THM,
chloroform, was found in all the samples tested, with three other
THM's found in most of the samples tested. In 1980, a study showed
that cancer rates were extremely higher in cities that chlorinated
their municipal water supplies. This was again attributed to the
influence of `THM's. People who drank chlorinated water were found
to have 53% greater chance of contracting colon cancer and up to
93% greater chance of contracting rectal cancer. These figures are
according to a report by the Presidents Council on Environmental
Quality. Also noted as a common additive to water and in the same
report, fluoride was reported to cause bone and kidney damage when
found in quantities that were considered to be much more than
adequate.
[0006] This is just the tip of the iceberg regarding clean water.
In addition, a variety of contaminants can enter municipal water
supplies as the water travels from the treatment plant to the
kitchen tap. Many water supply systems are well over one hundred
years old and are full of holes. As water mains deteriorate,
asbestos, lead, and many other toxic metals and substances are
released into the water. Inhibitors added to the water to slow down
deterioration of the pipes are sometimes themselves toxic.
Estimates indicate that there are more than 400,000 miles of
asbestos-cement/clay pipe still being used everyday in the U.S.A.
alone. An estimated 65 million people drink out of these water
systems daily. A 1979 official test survey by the EPA found twenty
percent of the cities examined had more than one million asbestos
fibers per liter of water, with eleven percent of the cities having
more than ten million fibers per liter of water. Studies in
California and Canada link the ingestion of asbestos with an
increased risk of cancer in the abdominal tract leading one to
deduce that much colon cancer could be reduced and/or prevented by
simply reducing or, even better, eliminating the amount of water
borne asbestos from municipal pipes.
[0007] The human body is composed of from 70% to 80% water and
requires a minimum of two quarts of water per day. Two quarts is
what one uses up per day through urination, defecation, evaporation
through the skin, and overall dehydration. This is the loss of
water from an inactive individual. An athlete uses at least twice
this amount or roughly at least four quarts per day. Depending on
which informational research source is used, one researcher
estimates that 75% of. Americans are dehydrated and that 37%
mistake thirst for hunger. A mere 2 percent drop in body water can
trigger fatigue and mental dysfunction.
[0008] Steven Kay of the International Bottled Water Association
said, "For this and other reasons, bottled water sales in the
United States increased from 3.1 billion in 1995 to 4.6 billion in
1999." In 2000, water sales topped 5.4 billion. The sweetheart of
water sales from 2000 to 2001 was oxygenated water, which increased
in sales by 45 percent. This culminated in over 100 million bottles
being sold by the end of 2001. This unique niche of bottled water,
with recent increased advertising and customer education on
research regarding oxygenated waters' benefits to the body, may
leave expectations of sales in the dust and push actual sales
beyond anyone's wildest dreams. Coupled with humankinds' creation
of urban deserts in many of today's cities, all water and beverage
sales are poised to skyrocket.
[0009] With over 70,000 chemicals, all created by man and in use
daily, and with an estimated 1000 new chemicals being developed
each year, it is obvious why we are living in a chemical bath of
our own creation. A recent study by the Clean Water Network
reported that one-third of our rivers, one-half of our estuaries,
and more than one-half of our lakes are not fit for fishing and
swimming forget the idea of drinking the water.
[0010] According to the Center for Disease Control, every year an
estimated 120 million Americans drink tap water contaminated with
waterborne diseases and known cancer causing chemicals. After
undertaking one of the most comprehensive water research studies
ever conducted, the Natural Resources Defense Council in 1993,
found that each year more than 900,000 people in the U.S. became
ill. As many as 900 of these people actually die from these
waterborne diseases. The United States Environmental Protection
Agency (EPA) lists over 700 toxic chemicals that can be found in
our nations' tap waters. Beginning in 1976, the EPA has monitored
the amount of toxins in the fat tissue of Americans; on a
consistent basis, thirteen very highly toxic compounds are found in
100 percent of all the people analyzed. The EPA continues to
conduct this analysis every year.
[0011] The EPA and several other governmental agencies state that
they only permit chemical levels that are considered "safe" in our
public water supplies. It is interesting that at every urban EPA
office there is always bottled water available for drinking. The
fact that our government cannot adequately protect everyone who
drinks publicly supplied water is one of the main reasons that
bottled water and in-home water filters have become such a huge
booming business.
[0012] Over the next twenty years, the Water Infrastructure Network
has estimated that $490 billion dollars will be necessary to repair
and maintain public drinking water systems throughout the United
States. What most Americans and people in general do not know about
is the disaster that has already begun in our oldest cities. The
clay pipes, many laced with asbestos to hold the clay together,
have eroded to the degree that dirt and contaminants are entering
into the water system. The asbestos has been tested at 70 parts per
million in one liter of water in several locations. It is obvious
why the bottled water business made over 7 billion dollars last
year by the peoples' effort to avert drinking water problems, some
not even discussed herein.
[0013] Oxygen, the most vital element of life itself, is also the
key to good health. We can live without water for weeks and go
without food for months, but we can survive for only minutes
without oxygen. Oxygen is the life-giving, life sustaining element.
Approximately 90% of the body's energy is created by oxygen. All of
the activities of the body, from brain function to elimination, are
regulated by oxygen. Our ability to think, feel and act comes from
the energy created by oxygen. The best way to optimize health is to
be sure that we oxygenate every cell in our body. The more oxygen
we have in our system, the more energy we produce. This is more
important today than ever before, because of a general deficiency
of oxygen intake directly related to the overall lack of exercise
for the average person.
[0014] One of the many reasons for a lack of oxygen is our polluted
atmosphere. Other reasons for oxygen depletion in the body include:
planetary deforestation; devitalized soil; processed foods and poor
diet; a clogged colon; automobile emissions; vitamin and mineral
deficiencies; lack of exercise; chlorinated water; bacterial and
fungal infections in the body; chemical pollutants; stress; poor
posture and breathing habits; and electronic smog.
[0015] There is less oxygen today (on an average) in our bodies'
systems to enable production of vital metabolic energy than ever
recorded. It is extremely important that we increase our intake of
oxygen if we are going to function on a level that gives our brain
and body a chance to operate at peak levels.
[0016] The power of added oxygen in water was first evidenced over
twenty years ago when European athletes dominated the world sports
arena with the Soviet Union clearly leading the pack. Chilled water
with oxygen added under pressure enabled the Soviet athletes to
increase the oxygen level in their bloodstream and lower pulse
rates by as much as 2 to 15 beats per minute. In addition, these
athletes increased overall energy levels, biological performance,
and stamina. When oxygen content is low in the body, the body
becomes tired, weaker, and endurance is compromised. The Soviets
outperformed the American athletes and we did not know how this was
achieved at the time. It took several years for us to catch up to
what the Soviets knew in the early 1970's. Knowledge of oxygenation
and water structure are the keys to understanding water's
biological behavior.
[0017] Blood plasma holds approximately three percent dissolved
oxygen and red blood cells (hemoglobin) hold ninety seven percent.
From the red blood cells the oxygen passes out into the plasma and
is transferred to cells that need oxygen during metabolic
processes. These cells pass C02 back to the plasma where it is then
picked up by the red blood cells. Free oxygen in the blood then
becomes the purging agent to clean and purify the blood. However,
there must be enough free oxygen in the blood to enable this
process. Many times, there is too much environmental pollution to
allow for this excess free oxygen in the blood, and this is where
OSIRIS water/liquid has a tremendous place in the market of
oxygenated water (virtually including almost every person in the
world).
SUMMARY OF THE INVENTION
[0018] An object of the invention is to solve at least the above
problems and/or disadvantages and to provide at least the
advantages described hereinafter.
[0019] To adequately and sufficiently oxygenate and structure water
insofar that when consumed, whether by internal or external
absorption, there is a distinct and definite increase in hydration,
oxygenation and healthy metabolic changes regarding organic life
processes.
[0020] In various embodiments, a composition includes
microstructured water having a boiling point higher than the
boiling point of double distilled water.
[0021] In various embodiments, the composition may include
dissolved oxygen. The dissolved oxygen may be present in an amount
greater than 20 ppm.
[0022] In various embodiments, the microstructured water has a
cluster size of 6-8 molecules.
[0023] In various embodiments, the microstructured water has a
cluster factor of about at least 30.
[0024] In various embodiments, the composition may include at least
one member selected from the group consisting of vitamins, plant
extracts, animal extracts, pharmaceutically active agents,
flavorants and colorants.
[0025] Additional advantages, objects, and features of the
invention will be set forth in part in the description which
follows and in part will become apparent to those having ordinary
skill in the art upon examination of the following or may be
learned from practice of the invention. The objects and advantages
of the invention may be realized and attained as particularly
pointed out in the appended claims.
BRIEF DESCRIPTION OF THE DRAWINGS
[0026] The invention will be described in detail with reference to
the following drawings in which like reference numerals refer to
like elements wherein:
[0027] FIG. 1A is a block diagram of a system for making and tuning
super-oxygenated and structured water, in accordance with an
embodiment of the invention;
[0028] FIGS. 1B-1C are flow charts of methods for making
super-oxygenated and structured water, in accordance with an
embodiment of the invention;
[0029] FIG. 1D is a flow chart of a method for tuning
super-oxygenated and structured water, in accordance with an
embodiment of the invention;
[0030] FIG. 2A is a block diagram of a system for preparing water
with a stable negative ORP, in accordance with an embodiment of the
invention;
[0031] FIG. 2B is a flow chart of a method for preparing water with
a stable negative ORP, in accordance with an embodiment of the
invention;
[0032] FIG. 2C is a block diagram of a water preconditioning
system, in accordance with an embodiment of the invention;
[0033] FIG. 2D is a flow chart of a method for preconditioning
water, in accordance with an embodiment of the invention;
[0034] FIG. 3A is a schematic side view of a magnetic structuring
stage for a water preconditioning system, in accordance with an
embodiment of the invention;
[0035] FIG. 3B is a graph of magnetic field strength versus
location for donut rings of a magnetic structuring stage, in
accordance with an embodiment of the invention;
[0036] FIG. 4A is a block diagram of an oxygen/water combining
system, in accordance with an embodiment of the invention;
[0037] FIG. 4B is a flow chart of an oxygen/water combining method,
in accordance with an embodiment of the invention;
[0038] FIG. 5A is a block diagram of a structured oxygen generating
machine, in accordance with an embodiment of the invention;
[0039] FIG. 5B is a flow chart of a method for producing structured
oxygen, in accordance with an embodiment of the invention;
[0040] FIG. 5C is a perspective/cross sectional view of the oxygen
enhancer shown in FIG. 4A, in accordance with an embodiment of the
invention;
[0041] FIG. 5D is a front view of a screen shown in FIG. 5C;
[0042] FIGS. 5E-5G are front and side views of a ring shown in FIG.
5C;
[0043] FIG. 6A is a schematic side view of a first magnetic
structuring stage for a structured oxygen generating machine, in
accordance with an embodiment of the invention;
[0044] FIG. 6B is a schematic side view of a second magnetic
structuring stage for a structured oxygen generating machine, in
accordance with an embodiment of the invention;
[0045] FIG. 7A is a schematic block diagram of a cone system, in
accordance with an embodiment of the invention;
[0046] FIG. 7B is a schematic side view of an exemplary cone
structure, in accordance with an embodiment of the invention;
[0047] FIG. 7C is a schematic top view of the cone structure of
FIG. 7B;
[0048] FIG. 7D is a flow chart of a method for spinning oxygen
using a cone system, in accordance with an embodiment of the
invention;
[0049] FIG. 8A is a schematic side view of a coil system, in
accordance with an embodiment of the invention;
[0050] FIG. 8B is a schematic top view of the coil system of FIG.
8A;
[0051] FIG. 8C is a flow chart of a method of using the coil system
of FIGS. 8A-8B;
[0052] FIGS. 9A and 9B are, respectively, schematic top and side
views of a multi-coil system, in accordance with an embodiment of
the invention;
[0053] FIG. 9C is a schematic side view of the multi-coil system of
FIG. 9A;
[0054] FIGS. 9D and 9E are schematic plan and side views of a pipe
entry point into a coil set, according to an embodiment of the
invention;
[0055] FIG. 9F is a flow chart of a method of using the multi-coil
system of FIGS. 9A-9C;
[0056] FIG. 10A is a block diagram of a structured ozone machine,
in accordance with an embodiment of the invention;
[0057] FIG. 10B is a flow chart of a method structuring ozone, in
accordance with an embodiment of the invention.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
[0058] The process and apparatus of the present invention are also
suitable for use in aerobic processes and other processes such as
therapeutic processes advantageously employing oxygen containing
liquids.
[0059] As used throughout the specification and the claims,
reference to an "aerobic" process generally includes all chemical
and microbiological processes in which such a process is carried
out or is promoted in a liquid medium in the presence of oxygen. As
used,throughout the specification and the claims "therapeutic"
processes involve the oxygenation of the body or its parts by
treatment with an agent in a liquid vehicle containing dissolved
oxygen.
[0060] Suitably aerobic processes in which water oxygenated in
accordance with the present invention can be employed include, for
example, processes in which heretofore water has been aerated such
as by bubbling air thereinto, and also in situ or ex situ
bioremediation of contaminated (e.g. with petroleum products)
surface and ground waters; wastewater, sludge, and animal waste
treatment, both by fixed film and by suspended growth methods;
rehabilitation of atrophying lakes; biochemical oxygen demand (BOD)
measurement techniques; fresh water aquaculture (e.g. fish
farming); odor suppression barriers for anaerobic processes; and
insolubilization of dissolved contaminants (e.g. Fe., and Mn ions)
for removal by filtration or sedimentation.
[0061] In view of the particularly good oxygen retention of liquids
oxygenated by the present invention kept in containers, a
particularly advantageous new aerobic use of those liquids was
discovered. In accordance with a further feature of the present
invention, such oxygenated liquids can be advantageously employed
as the fermentation liquor of all kinds of fermentation processes,
such as drug production or food processing by microorganisms.
[0062] Microorganisms, such as bacteria, consume massive quantities
of oxygen in the process of assimilating or breaking down waste.
The rate at which oxygen can be introduced into the biomass is a
substantial limiting factor on how quickly a breakdown by
oxygenation can be achieved. The problem with known process
technologies is that oxygen introduction by aeration is highly
inefficient because air contains only 21% percent oxygen. Thus, 79%
percent of the energy used by aerators is wasted in pumping useless
nitrogen. Therefore, the use of highly oxygenated water, in
accordance with the present invention, in such aerobic processes is
expected to be about 5 times more efficient, also to obtain thereby
a like extent of energy efficiency improvement. The dissolved
oxygen content of water treated with embodiments of the present
invention can be greater than 20 ppm, can be greater than 40 ppm,
can be greater than 60 ppm, can be greater than 80 ppm, can be
greater than 100, ppm, can be greater than 120 ppm, and can be
greater than 140 ppm. Thus, the infusion of water with 40-50 mg/l
of oxygen allows for a considerably more efficient and much more
rapid aerobic treatment, compared to 7-10 mg/l for the normal
oxygen content of water, and just slightly more when a conventional
bubbling aerator is used with 20% oxygen containing air.
Furthermore, as the equilibrium oxygen content of water is used up,
its dissolved oxygen content rapidly decreases.
[0063] Another property of embodiments of the water involves its
increased density. The increased density can be described using the
term "cluster factor", that can be defined by relative density to
double distilled water minus 1.0, then multiplied by 100,000. The
cluster factor of water treated with embodiments of the present
invention can be greater than 150, can be greater than 200, can be
greater than 250, can be greater than 300, and can be greater than
350.
[0064] Another property of embodiments of the water involves its
pH. The pH of water treated with embodiments of the present
invention, as measured by litmus paper, can be between 7.5 and 8.5.
The pH of water treated with embodiments of the present invention,
as measured by a standard glass electrode pH meter, can be between
9.2 and 9.5.
[0065] Suitable therapeutic processes in which liquids made in
accordance with the present invention can be advantageously
employed include, for example, increasing the oxygen content of
blood and tissues; oxygenation of wounds to increase the rate of
healing and to reduce infections; oxygenated organ transplant
storage media; tumor oxygenation for radiation therapy and
chemotherapy; lung bypass by oxygenated liquids in case of
pulmonary deficiencies; carbon monoxide poisoning; mouthwashes;
dentifrices; topical, including cosmetic, treatment media; contact
lens treating solutions; and cell level therapeutic
applications.
[0066] In view of the especially good oxygen retention of liquids
oxygenated by the present invention kept in containers, a
particularly advantageous new therapeutic product of those liquids
was discovered. In accordance with a further feature of the present
invention, such oxygenated liquids can be employed as solvents for
physiological saline isotonic solutions, especially when kept in
sealed, sterile containers.
[0067] In cosmetics and toiletries, the liquids of the present
invention may be incorporated into a beauty product in process by
addition, mixing, wetting and other methods in the course of
production of the beauty product.
[0068] In this case, the state and form of the cosmetics and
toiletries are not specifically limited. For example, the liquids
of the present invention may be used as is, may be used in a state
diluted with double distilled water, alcohol or the like, and may
be used in a gel or paste state obtained by adding a thickener,
which processing are conducted for improvement on handle-ability,
and in other states and forms in use. The water may be mixed into a
beauty product in a liquid state as is, or it may be diluted or
concentrated prior to the use as desired.
[0069] The state and form as a commodity of a beauty product in the
present invention is not specifically limited as far as the beauty
product is a beauty product into which a liquid of the present
invention is mixed, and a beauty product of the present invention
has only to be processed in a similar state and form to those of a
known beauty product. Concrete examples thereof in which the liquid
can be used include a non-drug product, a skin-care product, a
makeup product, a hair care product, fragrance, a body care
product, an oral care product and the like.
[0070] Examples thereof further include a face cleansing cream, a
toilet lotion, a milky lotion, cream, gel, essence, pack, mask,
foundations, lip sticks, cheek rouges, a brow, eye beauty product,
manicure enamels, a shaving lotion, a hair washing product, a hair
raising agent, a hair makeup product, a perfume, cologne, soap, a
liquid body cleaning agent, a sun care product, a hand care
product, a bath product, a tooth paste, and an oral cleaning
agent.
[0071] The cosmetics and toiletries of the present invention
contain a liquid of the present invention mixed therein as a
feature, while no specific limitation is placed on other
components, and additives currently used in cosmetics and
toiletries can be properly mixed in.
[0072] Concrete examples of other components include hydrocarbons,
such as squalane, liquid paraffin and the like; animal/vegetable
oils, such as olive oil, beef tallow and the like; esters, such as
isopropyl myristate, cetyl octate and the like; natural
animal/vegetable waxes, such as carnauba wax, beeswax and the like;
surfactants, such as glycelyl stearate, and sorbitan stearate;
silicone oils, such as dimethylpolysiloxane,
methylphenylpolysiloxane and derivative thereof; fluorine
containing resins, such as perfluoropolyether and the like;
alcohols, such as ethanol, ethylene glycol, glycerin and the like;
water-soluble polymers, such as carboxyvinyl polymer, carrageenan,
carboxymethyl cellulose sodium and the like; proteins, such as
collagen, elastin and the like and hydrolyzates thereof; powders of
titanium dioxide, zinc oxide, talk, mica, silicic anhydride, nylon
powder, alkyl polyacrlylate, powder of alumina, iron oxide and the
like; an ultraviolet absorbent; vitamines; an antiphlogistic agent;
amino acids and derivative thereof; lecithin; a colorant; a
perfume; an antiseptic agent; an antioxidant and the like.
[0073] The extent of cosmetics and toiletries in the sense of words
has been extended because of recent diverse requirements therefor,
and cosmetics and toiletries of the present invention are not
necessarily strictly restricted in respect of the definition
thereof. That is, cosmetics and toiletries of the present invention
means cosmetics and toiletries in a general sense into which an
activating agent of the present invention is properly mixed.
Therefore, cosmetics and toiletries of the present invention
include all products by which a liquid of the present invention is
taken ;into the body of an organism in a manner of transdermal or
endermic absorption.
[0074] Food additives related to the present invention are
characterized by that in which a liquid of the present invention is
mixed thereinto and a food additive is added, mixed or incorporated
by wetting or similar method into a food or a beverage in the
course of production of the food or the beverage for the purpose of
processing or preservation of the food or the beverage. A state and
a form of a food additive is not specifically restricted to a
particular pair and, for example, the water may be used in mixing
into a sweetner, a sourness flavoring, a bitterness flavoring, a
deliciousness flavoring, an oiliness flavoring and the like at a
proper content. The water may also be used in a gel or paste state
processed by adding a thickener or the like for improvement on
handle-ability, may be used in a liquid state of 100%, or may be
used in a dilute or concentrated state as well.
[0075] To be more detailed, a food additive related to the present
invention can be to satisfy a person's preference and to prevent
modification, or rotting of a food. That is, the food additives may
be; necessary for production, improvement on quality, preservation
of quality and nutrition enhancement, while a state and a form in
processing may be similar to those of known food additives.
Concrete examples thereof include flavorings, such as a saline
solution, salt, a sauce, drips, a soupe, an original broth and the
like; a preserving agent; a production auxiliary; a filtering
auxiliary; a clarificant; a quality sustaining agent; a sterilizing
agent; an antimicrobial agent; a disinfectant and the like.
[0076] Note that in order to further improve a quality of a food
additive of the present invention, the inventive water agent is
preferably processed into the food additive in a working condition,
in which the intermediate is brought into contact to the external
air (oxygen) on the lowest possible level or in a low temperature
condition. For example, the processing is preferably conducted in a
condition in which no activity of mineral components is degraded,
such as in a nitrogen atmosphere, at a low temperature or in a
freeze drying condition. The food additive as processed is
preferably immediately and in a short time packed, so as to be
brought into contact with oxygen on the lowest possible level, for
example in a vacuum package, in a nitrogen-filled package or in
gas-tight package with an antioxidant therein. Such packages are
preferably adopted, since the beneficial effects of the inventive
water can be sustained over a long term.
[0077] A food related to the present invention is a food in which a
liquid or a food additive of the present invention is added as a
feature. Since foods can be mixed with a liquid or a food additive
under various categories, such as an agricultural food, a livestock
food, a fishery food, a fermented food, a canned food, an instant
food and the like, according to states and forms of respective food
additives described above, no specific limitation is imposed on a
kind, and state and form of food related to the present invention.
Concrete examples of foods that can be named include breads,
noodles, bean curd, a dairy product, a meat processed product, soy
source, miso, edible fat and oil, an oil and fat processed product,
a fish paste product, sweet stuff, vegetables, pickles and the
like. Concrete examples of addition methods and products applied
therewith that can be named include: soy source obtained by mixing
inventive water into soybean, wheat and seed koji to ferment them
and miso obtained by mixing processed inventive water into soybean,
rice and barley to ferment them.
[0078] Further examples of foods of the present invention include
bean curd obtained by using the inventive water as a brine for
coagulation of soybean milk, pickles obtained by using the
inventive water as a salty component in a solution, a food added
with an inventive liquid or a food additive for retaining freshness
and a food immersed in an inventive liquid or a food additive for
retaining freshness.
[0079] Still further examples of foods of the present invention
include nutritional supplements and the like such as health foods
in states and forms including liquid, powder, a tablet, a capsule,
in which the inventive liquid or food additive is incorporated.
[0080] A beverage related to the present invention is a beverage in
which a water of the present invention and/or a food additive of
the present invention is added as a feature. Since, as to a kind,
state and form of beverages related to the present invention, a
inventive liquid or a food additive can be added to various, kinds
of beverages according,to a kind, state and form thereof, no
specific limitation is imposed on a kind, state and form of
beverage. Examples thereof that can be named include alcoholic
beverages such as brewed sake, synthetic sake, shochu, sweet sake,
beer, whisky, liqueur, fruit liquor and the like, and favorite soft
beverages or refreshing beverages such as fruit juice, concentrated
fruit juice, nectar, soda pop, cola beverage, teas, coffee, black
tea and the like.
[0081] Note that in order to further improve a quality of a food
and a beverage related to the present invention, the inventive
liquid is preferably processed into foods or beverages in a working
condition in which the intermediate is brought into contact to the
external air (oxygen) on the lowest possible level or in a low
temperature condition. For example, the processing is preferably
conducted in a condition in which no activity of mineral components
is degraded, such as in a nitrogen atmosphere, at a low temperature
or in a freeze drying condition. Preferably, the food additive as
processed is immediately and in a short time packed so as to be
brought into contact with oxygen on the lowest possible level, for
example in vacuum package, in nitrogen-filled package or in
gas-tight package with an antioxidant therein. Such packages are
preferably adopted since the benefits of the inventive liquid can
be sustained over a long term.
[0082] The boundaries between a food additive, a food and a
beverage in the sense of words have been ambiguous because of
recent diverse requirements for foods. For example, since miso, soy
source and the like are flavorings (food additives) and foods, sake
classified in alcoholic beverages is a food and a beverage, and
sweet sake classified in alcoholic beverage is also flavoring (food
additive). Therefore, the boundaries in a food additive, a food and
a beverage related to the present invention are not necessarily
strictly restricted in respect of the definition thereof. That is,
food additives, and foods and beverages of the present invention in
principle means food compositions in a general sense into which a
liquid of the present invention is properly mixed. Accordingly,
food compositions of the present invention include all products
through which an inventive liquid is taken into the body of an
organism in a manner of oral uptake.
[0083] It will be recognized by those skilled in the art that the
water/liquids of the present invention can be further modified in
any number of ways. For example, following formation of structured
water, the water may be oxygenated as described herein, further
purified, flavored, distilled, irradiated, or any number of further
modifications known in the art and which will become apparent
depending on the final use of the water.
[0084] In another embodiment, the present invention provides
methods of modulating the cellular performance of a tissue or
subject. The inventive water (e.g., oxygenated microcluster water)
can be designed as a delivery system to deliver hydration,
oxygenation, nutrition, medications and increasing overall cellular
performance and exchanging liquids in the cell and removing
edema.
[0085] It is also contemplated that the water of the present
invention provides beneficial effects upon consumption by a
subject. The subject can be any mammal (e.g, equine, bovine,
porcine, murine, feline, canine) and is preferably human. The
dosage of the water (or oxygenated water) will depend upon many
factors recognized in the art, which are commonly modified and
adjusted. Such factors include, age, weight, activity, dehydration,
body fat, etc. Typically 0.5 liters/day of the water of the
invention provide beneficial results. In addition, it is
contemplated that the water of the invention may be administered in
any number of ways known in the art including, for example, orally,
topically, buccally, sublingually, parenterally, intramuscularly or
intravenously, either alone or mixed with other agents, compounds
and chemicals. It is also contemplated that the water of the
invention may be useful to irrigate wounds or at the site of a
surgical incision. The water of the invention can have use in the
treatment of infections. For example, infections by anaerobic
organisms may be beneficially treated with the oxygenated forms of
the water. In another embodiment, the water of the invention can be
used to lower free radical levels and, thereby, inhibit free
radical damage in cells.
[0086] In one embodiment, the water may contain a sweetener (i.e.,
a compound that imparts a sweet taste but does not increase the
blood glucose levels of the patient). Examples include a sugar
alcohol and non-nutritive sugars. As used herein, the term sugar
alcohol refers to reduced sugars. The preferred sugar alcohol are
mono-saccharide alcohols and disaccharide alcohols. The
monosaccharide alcohols have the formula HO--CH.sub.2
(CHOH)n-CH2OH, wherein n is 2-5. They also include tetritols,
pentitols, hexitols and heptitols. Examples of sugar alcohols
include erythritol, theritol, ribitol, arabinitol, xylitol,
allitol, dulcitol, glucitol, sorbitol, mannitol, altritol, iditol,
maltitol, lactitol, isomalt, hydrogenated starch hydrolysate and
the like. The sugar alcohols, especially the monosaccharide
alcohols, may be utilized as a racemic mixture or in the D or L
form.
[0087] The non nutritive sweeteners are patentably sweet but are
non-caloric. Examples include L-sugars, aspartame, alitame,
acesulfame-K, cyclamate, stevioside, glycyrrhizin, sucralose,
neohesperidin, dihydrochalcone, thaumatin saccharin and its
pharmaceutically acceptable salts (e.g., calcium), and the
like.
[0088] In one embodiment of the present invention, it is preferred
that the sweetener be present in the water in amounts ranging from
about 40% to about 80% by weight and more preferably from about 50%
to about 70% and most preferably from about 55% to about 65%. In
addition, it is preferred that the weight ratio of sweetener to
alkyl hydroxyethyl cellulose, when present, ranges from about 400
to about 800, and, most preferably, from about 500 to about
600.
[0089] Other optional ingredients which may be present in certain
waters of the present invention include buffers, such as citric
acid or its corresponding salts or acetic acids and its salts,
flavoring agents, such as peppermint, oil of wintergreen, orange,
or cherry flavoring, and the like, surfactants, thickeners,
preservatives, such as methyl and propyl parabens, and the like,
anti-oxidants, such as benzoate salts, and the like, chelating
agents, such as EDTA and its salts and the like.
[0090] In certain embodiments, the waters of the present invention
can be administered to a mammal in need thereof by topical,
systemic, subscleral, transscleral, or intravitreal delivery.
Intravitreal delivery may include single or multiple intravitreal
injections, or via an implantable intravitreal device that releases
the water in a sustained capacity. Intravitreal delivery may also
include delivery during surgical manipulations in treatment for
retinal detachments, diabetic retinopathy, or macular degenerations
as either an adjunct to the intraocular irrigation solution or
applied directly to the vitreous during the surgical procedure.
[0091] Minimally invasive transscleral delivery can be used to
deliver an effective amount of the water to the retina with
negligible systemic absorption. Transscleral delivery utilizes the
sclera's large and accessible surface area, high degree of
hydration that renders it conductive to water-soluble substances,
hypocellularity with an attendant paucity of proteolytic enzymes
and protein-binding site, and permeability that does not
appreciably decline with age. An osmotic pump loaded with the
inventive water can be implanted in a subject so that the active
compounds are transsclerally delivered to the retina in a
slow-release mode. (Ambati, et al., Invest. Ophthalmol. Vis. Sci.,
41: 1186-91 (2000)).
[0092] The inventive waters may also be administered topically by
administering the active compounds to a patient by any suitable
means, but are preferably administered by a liquid or gel
suspension of the water in the form of drops, spray or gel.
Alternatively, the water may be applied, for example to the eye,
via liposomes. Further, the water may be infused into the tear film
via a pump-catheter system. Another embodiment of the present
invention involves the water contained within a continuous or
selective-release device, for example, polymeric ocular inserts for
the administration of drugs. (Alza Corp., Palo Alto, Calif.), or in
the intra-vitreal implant for the gradual release of
pharmaceuticals for the treatment of eye conditions (Bausch &
Lomb, Claremont, Calif.).
[0093] As an additional embodiment, the inventive water can be
contained within, carried by, or attached to contact lenses that
are placed on the eye. Another embodiment of the present invention
involves the water contained within a swab or sponge that can be
applied to the desired surface. Another embodiment of the present
invention involves the water contained within a liquid spray that
can be applied to any desired surface, such as the ocular
surface.
[0094] The inventive water may be administered systemically. The
term "systemic" as used herein includes subcutaneous injection,
intravenous, intramuscular, intraesternal injection, infusion,
inhalation, transdermal administration, oral administration, and
intra-operative instillation.
[0095] Liquid formulations containing water of the present
invention may be sterile and non-sterile injectable formulations.
For instance, the formulation may be an aqueous or oleaginous
suspension. The suspensions may be formulated according to
techniques known in the art using suitable dispersing or wetting
agents and suspending agents.
[0096] The injectable formulation may also be a sterile injectable
solution or suspension in a non-toxic parenterally-acceptible
diluent or solvent. Suitable diluents and solvents for injectable
formulations include 1,3-butanediol, Ringer's solution and isotonic
sodium chloride solution. Sterile, fixed oils are conventionally
employed as a solvent or suspending medium. Suitable fixed oils
include, but are not limited to, synthetic mono- or di-glycerides,
fatty acids, such as oleic acid and its glyceride derivatives, and
natural pharmaceutically-acceptable oils, such as olive oil, castor
oil, and polyoxyethylated derivatives thereof. (Sigma Chemical Co.;
Fisher Scientific) According to a preferred embodiment, oil
containing injectable formulations contain a long-chain alcohol
diluent.
[0097] Topical formulations of the present invention are typically
in the form of an ointment or suspension. Such formulations may be
administered for diseases of the eye, the skin, and the lower
intestinal tract. Suitable suspending agents, diluents, and dosing
vehicles for such formulations include, but are not limited to,
mineral oil, liquid petrolatum, white petrolatum, propylene glycol,
polyoxyethylene, polyoxypropylene compound and emulsifying wax.
(Sigma Chemical Co.; Fisher Scientific) Alternatively, the topical
formulation can be in the form of a lotion or cream. Suitable
suspending agents, diluents, and dosing vehicles for such
formulations include, but are not limited to, mineral oil, sorbitan
monostearate, polysorbate 60 cetyl esters wax, cetearyl alcohol,
2-octyldodecanol, and benzyl alcohol. (Sigma Chemical Co.; Fisher
Scientific) Topical application for the lower intestinal tract can
be effected in a rectal suppository formulation or in a suitable
enema formulation. The formulation may also be administered via a
transdermal patch as known in the art.
[0098] The liquid formulation containing the inventive water may
also be applied ophthalmically. A preferred ophthalmic formulation
of the present invention is a micronized suspension in isotonic, pH
adjusted sterile saline. A preservative, such as benzalkonium
chloride, may be included in the formulation but is not necessary
as a preservative due to the nature of the invention.
Alternatively, the ophthalmic formulation is in an ointment, for
example, containing petrolatum.
[0099] Nasal aerosol and inhalation formulations of the invention
may be prepared by any method in the art. Such formulations may
include dosing vehicles, such as saline, preservatives, such as
benzyl alcohol, absorption promoters to enhance bioavailability,
fluorocarbons used in the delivery systems, e.g., nebulizers, etc.,
solubilizing agents, dispersing agents, or any combination of any
of the foregoing.
[0100] The formulations of the present invention may be
administered systemically., The term "systemic" as used herein
includes parenteral, topical, oral, spray inhalation, rectal,
nasal, bucal, and vaginal administration. The term "parenteral" as
used herein includes subcutaneous, intravenous, intramuscular,
intra-articular, intra-synovial, intrasternal, intrathecal,
intrahepatic, intralesional and intracranial administration.
Preferably, the compositions are administered orally,
intraperitoneally or intravenously.
[0101] One systemic method involves an aerosol suspension of
respirable particles comprising the inventive water, which the
subject inhales. The water would be absorbed into the bloodstream
via the lungs, and subsequently contact the lacrimal glands in a
pharmaceutically effective amount. The respirable particles are
preferably liquid, with a particle size sufficiently small to pass
through the mouth and larynx upon inhalation. In general, particles
ranging from about 1 to 10 microns, but more preferably 1-5
microns, in size are considered respirable.
[0102] Another method of systemically administering the active
compounds to the eyes of a subject involves administering a
liquid/liquid suspension in the form of eye drops or eye wash or
nasal drops of a liquid formulation, or a nasal spray of respirable
particles that the subject inhales. Liquid pharmaceutical
compositions containing the inventive water for producing a nasal
spray or nasal or eye drops may be prepared by combining the
inventive water with a suitable vehicle, such as sterile pyrogen
free water or sterile saline by techniques known to those skilled
in the art.
[0103] The inventive water may also be systemically administered to
eyes through absorption by the skin using transdermal patches or
pads. In this embodiment, the inventive water is absorbed into the
bloodstream through the skin.
[0104] Other methods of systemic administration of the inventive
water involves oral administration, in which compositions
containing the inventive water are in the form of lozenges, aqueous
or oily suspensions, viscous gels, chewable gums, emulsion, soft
capsules, or syrups or elixirs. Additional means of systemic
administration of the inventive water to the eyes of the subject
would involve a suppository form of the water, such that a
therapeutically effective amount reaches the eyes via systemic
absorption and circulation.
[0105] Further means of systemic administration of the inventive
water involve direct intra-operative instillation of a gel, cream,
or liquid suspension form of a therapeutically effective amount of
the water.
[0106] For topical application, a solution containing the inventive
water may contain a physiologically compatible vehicle, as those
skilled in the ophthalmic art can select, using conventional
criteria. The vehicles may be selected from the known ophthalmic
vehicles which include, but are not limited to, saline solution,
polyethers such as polyethylene glycol, polyvinyls such as
polyvinyl alcohol and povidone, cellulose derivatives such as
methylcellulose and hydroxypropyl methylcellulose, petroleum
derivatives such as mineral oil and white petrolatum, animal fats
such as lanolin, polymers of acrylic acid such as
carboxypolymethylene gel, vegetable fats such as peanut oil,
polysaccharides such as dextrans, glycosaminoglycans such as sodium
hyaluronate, and salts such as sodium chloride and potassium
chloride.
[0107] For systemic administration, such as injection and infusion,
the pharmaceutical formulation is prepared in a sterile medium. The
inventive water, depending on the vehicle and concentration used,
can either be suspended or dissolved in the vehicle. Adjuvants such
as local anaesthetics, preservatives and buffering agents can also
be dissolved in the vehicle. The sterile injectable preparation may
be a sterile injectable solution or suspension in a non-toxic
acceptable diluent or solvent. Among the acceptable vehicles and
solvents that may be employed are saline solution or Ringer's
solution.
[0108] For oral use, an aqueous suspension may be prepared by
addition of the inventive water to dispersible powders and granules
with a dispersing or wetting agent, suspending agent, one or more
preservatives, and other excipients. Suspending agents include, for
example, sodium carboxymethylcellulose, methylcellulose and sodium
alginate. Dispersing or wetting agents include naturally-occurring
phosphatides, condensation products of an allylene oxide with fatty
acids, condensation products of ethylene oxide with long chain
aliphatic alcohols, condensation products of ethylene oxide with
partial esters from fatty acids and a hexitol, and condensation
products of ethylene oxide with partial esters derived from fatty
acids and hexitol anydrides. Preservatives include, for example,
ethyl, and n-propyl p-hydroxybenzoate. Other excipients include
sweetening agents (e.g., sucrose, saccharin), flavoring agents and
coloring agents. Those skilled in the art will recognize the many
specific excipients and wetting agents encompassed by the general
description above.
[0109] Formulations for oral use may also be presented as soft
gelatin capsules wherein the inventive water is administered alone
or mixed with an oil medium, for example, peanut oil, liquid
paraffin or olive oil. Formulation for oral use may also be
presented as chewable gums by embedding the active ingredient in
gums so that the inventive water is slowly released upon
chewing.
[0110] For rectal administration, the compositions in the form of
suppositories can be prepared by mixing the inventive water with a
suitable non-irritating excipient that is solid at ordinary
temperatures but liquid at the rectal temperature and will
therefore melt in the rectum to release the water. Such excipients
include cocoa butter and polyethylene glycols.
[0111] FIG. 1A is a block diagram of a system for making and tuning
super-oxygenated and structured water, in accordance with one
embodiment of the present invention. The system 1 includes system
10 for producing or making super-oxygenated and structured water
coupled via pipe 27 to a system 20 for tuning super-oxygenated and
structured water. The term pipe refers to any component configured
to provide fluid or gaseous communication between two components.
The pipe may be, for example, a PVC pipe, a crystal pipe, flexible
tubing, or other type of conduit.
[0112] System 10 includes a water preparation system 103 coupled to
an oxygen/water combining system 113 via a holding tank 109.
Oxygen/water combining system 113 is in turn coupled to a cone
system 121 via holding tank 109. System 20 for tuning
super-oxygenated and structured water includes a coil system 123
coupled to a structured ozone machine 125 and multi-coil system
127.
[0113] Water preparation system 103 includes a water
preconditioning system 100 and an electrolysis machine 101 coupled
by a pipe 75, which together comprise a system for preparing water
with a stable negative oxidation reduction potential (ORP). Output
of system 103, in particular, from electrolysis machine 101, is
either alkaline water, which is output via a pipe 105 to holding
tank 109, or acidic water, which is output via a pipe 107 to an
acid water tank 110. Both the alkaline water output via pipe 105
and the acidic water output via pipe 107 have a stable negative
oxidation reduction potential (ORP). The alkaline water is input to
holding tank 109, which is in turn output via a pipe 111 to the
oxygen/water combining system 113. Holding tank 109 may be a single
tank or a plurality of tanks, for example, three tanks arranged in
series. A pump 523 and pressure gauge 519 are preferably provided
between the holding tank 109 and the oxygen/water combining system
113 to control the flow of water from the holding tank 109 to the
oxygen/water combining system 113.
[0114] The oxygen/water combining system 113 includes a structured
oxygen generating machine 600 and a diffusion chamber 115. The
structured oxygen generating machine 600 outputs oxygen via a pipe
117, which is coupled to pipe 111 and pipe 118 by a valve 119.
Water and oxygen flow together from valve 119 to the diffusion
chamber 115 via pipe 118. The oxygen/water combining system 113
outputs oxygen enriched water to cone system 121 via pipe 25.
[0115] As set forth above, the system for tuning super-oxygenated
and structured water 20 is coupled to the system for producing
super-oxygenated and structured water 10 via pipe 27. The system
for tuning super-oxygenated and structured water 20 includes coil
system 123, structured ozone machine 125, and multi-coil system
127. Coil system 123 receives the oxygen enriched water from system
10 via pipe 27, and combines and outputs oxygen enriched water via
a pipe 29. Structured ozone machine 125 outputs structured ozone
via a pipe 31, which is coupled to pipe 29 and pipe 35 by a valve
33. The structured ozone from structured ozone machine 125 is
combined with the super-oxygenated and structured water in pipe 29
at valve 33 and the combination of structured ozone and
super-oxygenated and structured water is directed via pipe 35 to
multi-coil system 127.
[0116] Coil system 123 tunes water received via pipe 27, and
multi-coil system 127 tunes the combined water and ozone received
via pipe 35 to yield super-oxygenated and structured water that is
output via pipe 37. Pipe 37 returns the super-oxygenated and
structured water to holding tank 109, from which the water may be,
for example, bottled for human consumption or other uses.
[0117] Water preconditioning system 100, oxygen/water combining
system 113, including structured oxygen generating machine 600 and
diffusion chamber 115, cone system 121, coil system 123, structured
ozone machine 125, and multi-coil system 127 will be described in
more detail below.
[0118] FIG. 1B is a flow chart of a method for producing
super-oxygenated and structured water, in accordance with one
embodiment of, the present invention, and FIG. 1C is a flow chart
of a more detailed method for producing super-oxygenated and
structured water, in accordance with one embodiment of the present
invention. Referring to FIG. 1B, step S202 involves receiving water
from pipe 148 by system 103 for preparing water with stable
negative ORP. Water preconditioning system 100 in system 103
preconditions water for electrolysis at step S204. Electrolysis
machine 101 performs electrolysis at step S206. System 103 for
preparing water with a stable negative ORP outputs alkaline water
with its stable negative ORP via pipe 105 into holding tank 109 at
step S208. At step S210 water with a stable negative ORP is
received from holding tank 109 and is combined with oxygen at
oxygen/water combining system 113. At step S212, the combined
oxygen/water is received and spun by cone system 121. Finally, at
step S214, oxygen enriched structured water is output from cone
system 121.
[0119] FIG. 1C is a flow chart of a more detailed method for
producing super-oxygenated and structured water, in accordance with
one embodiment of the present invention. In particular, step S204
from FIG. 1A includes two substeps S204a and S204b for
preconditioning water. In particular, step S204 for preconditioning
water involves adding ozone to the water at step S204a, followed by
subjecting the water to magnetic fields at step S204b.
[0120] Step S210 of FIG. 1B, during which water is combined with
oxygen, is subdivided in FIG. 1C into step S210a, in which ozone
treated alkaline water is combined with oxygen, followed by step
S210b, in which oxygen enriched ozone treated alkaline water is
forced through the diffusion chamber 115.
[0121] Step 212 of FIG. 1B, during which water is spun, is shown in
FIG. 1C as step S212', in which oxygen enriched structured water is
received from the diffusion chamber 115 and input into the cone
system 101.
[0122] The system for tuning super-oxygenated and structured water
20 performs the steps shown in FIG. 1D as follows. At step S224
spun water is received from the system for producing
super-oxygenated and structured water 10, and is input into coil
system 123. The water output from the coil system 123 via pipe 29
is then combined with structured ozone received from structured
ozone machine 125 via pipe 31 at step S228. The combination of
water from coil system 123 and the structured ozone from structured
ozone machine 125 is input to multi-coil system 127 via pipe 35 at
step S232. Finally, at step S236, super-oxygenated, tuned, and
structured water is output from the system 20 and, in particular,
from multi-coil system 127.
[0123] FIG. 2A is a block diagram of the system for preparing water
with a stable negative ORP 103. System 103 includes water
preconditioning system 100 and electrolysis machine 101. As
discussed above, water preconditioning system 100 outputs water
preconditioned for electrolysis machine 101 via pipe 75. A cut off
valve 75A may be provided on pipe 75 to control the flow of the
water. The preconditioned water is, in turn, received by
electrolysis machine 101, and electrolysis is performed thereon to
yield both alkaline water output through pipe 105 to holding tank
109 and acidic water output through pipe 107 to acidic water tank
110. As discussed above, both the alkaline water and acidic water
have a stable negative ORP.
[0124] The acidic water output via pipe 107 is not designed for
consumption, but it has many other uses and advantages. For
example, acidic water can be used for cleaning many things, such as
pipes, etc. It can also be mixed with hair rinse. The mixture can
vary from pH 4.0 to pH 6.5 (6.7) and preferably between .about.4
parts per volume of water to .about.1 part per volume of hair rinse
all the way to .about.1 part per volume of water to .about.4 parts
per volume of hair rinse, and more preferably .about.1 part per
volume of water with .about.1 part per volume of hair rinse. It can
also be used in the same manner mixed with shampoo because it acts
as a reagent and helps clean oils out of hair.
[0125] Typically, when water is output from an electrolysis system,
the negative ORP that is created does not stay very long. It
typically only remains for minutes, at a time. The negative ORP of
water treated with embodiments of the present invention can be less
than -100. For both the alkaline and-the acidic water at pipes 105
and 107, respectively, typically the negative ORP begins at
.about.183 ORP. However, as the water settles out, some of the
electrons are given off due to a variety of reasons, and it
ultimately settles out at approximately .about.-170 ORP to
.about.-173 ORP. Both the alkaline and acidic water can maintain
.about.-170 to .about.-173 ORP for 6 months to up to .about.2 years
or more depending on the electromagnetic environment next to or
near the storage area. Water in this state gives a multitude of
free electrons which then can become an antioxidant in the blood.
At this point the water, both the alkaline water and the acidic
water, have structure. If the water in holding tank 109 is not
processed within .about.24 hours, the structure begins to
deteriorate, although the negative ORP remains, as discussed above.
Accordingly, for structure purposes, it is advantageous to continue
processing the alkaline water in holding tank 109 as quickly as
possible. That is, it is advantageous to proceed to output the
alkaline water in holding tank 109 via pipe 111 to the oxygen/water
combining system 113 as quickly as possible.
[0126] FIG. 2B is a flow chart of a method for preparing water with
a stable negative ORP, in accordance with one embodiment of the
present invention. System 103 for preparing water with a stable
negative ORP performs the following steps:
[0127] At step S412, water is preconditioned for electrolysis, and
at step S414 electrolysis is performed before outputting alkaline
and/or acidic water at step S416. Water preconditioning system 100
performs step S412 and electrolysis machine 101 performs step S414.
At step S412, system 103 outputs alkaline water to holding tank 109
via pipe 105 and acidic water to acid water tank 110 via pipe 107.
Step S412 for preconditioning water involves performing steps S402,
S404, S406, S408, and S410, discussed below in connection with FIG.
2D.
[0128] FIG. 2C shows a water preconditioning system 100 for
conditioning water for electrolysis, according to one embodiment of
the present invention. Water preconditioning system 100 includes a
filter system 104, a UV system 108, a circulating tank 112, an
ozone machine 116, and a magnetic structuring stage 120.
[0129] System 100 for preconditioning water operates generally as
follows. First, high quality water is received by filter system
104. High quality water may be water received from water source
152, for example, an aquafier well, preferably an aquafier well
located in certain geographic areas throughout the world, such as
northern New Mexico and, more specifically, New Mexico, Missouri
and Hawaii.
[0130] For example, a pump 140, such as a pressure pump, can be
used to pump the water from a well house 144 to filter system 104
via a pipe 148. The aquafier well 152 may be deep, for example,
.about.850 feet deep.
[0131] Water received by filter system 104 via pipe 148 is then
filtered by filter system 104 and output via a pipe 156 to UV
system 108. Water output from UV system. 108 via pipe 146 is then
input to circulating tank 112, which in turn is coupled via a pipe
136 to an ozone machine 116. Pipe 1063 is provided to allow water
to circulate between the circulating tank 112, the ozone machine
116 and the magnetic structuring stage 120.
[0132] The ozone machine 116 is selectively activatable. A valve
186 and bypass pipe 1062 are provided for selective bypass of the
magnetic structuring stage 120. After passing through magnetic
structuring stage 120, preconditioned water may be output via a
pipe 164.
[0133] Filter system 104 may be, for example, a four-stage
filtering system which includes a .about.10 .mu.m filter 124,
followed by a .about.5 .mu.m filter 128, followed by a .about.0.5
.mu.m filter 132, followed by a carbon filter 134.
[0134] UV system 108 preferably includes a UV chamber carbon block
filter (10'' 0.5 micron), and a UV #10 lamp (120V, 0.420 amp
unit).
[0135] The operation of system 100 will be explained with reference
to FIG. 2D, which is a flow chart of a method for preconditioning
water. Water from water source 152 is received by system 100 for
preconditioning water at step S402. The water is filtered by
filtering system 104 at step S404. Step S406 involves subjecting
the water to ultraviolet radiation with UV system 108. Steps
S408-S410 involve circulating water between circulating tank 112,
ozone machine 116 to add ozone to the water, and magnetic
structuring stage 120 to preferably subject the water to a series
of magnetic fields. Ozone machine 116 can be set between 1 mm/liter
10 SCFH and 1.2 mm/liter 15 SCFH, and the water is preferably
exposed to ozone less than .about.15 seconds per .about.100 gallons
to prevent burning, more preferably approximately between
.about.two and 10 seconds per .about.100 gallons, and most
preferably .about.5-8 seconds per 100 gallons. Step S412 involves
outputting water from magnetic structuring stage 120 as
preconditioned water, which can then be input to electrolysis
machine 101. A residual of 0.1-0.4 PPM of ozone is typically left
in the treated water.
[0136] As discussed above, circulating tank 112 is coupled via pipe
136 to ozone machine 116, which is in turn coupled to magnetic
structuring stage 120 via pipe 160. Pipe 1063 connects magnetic
structuring stage 120 to circulating tank 112 to form a complete
circulation loop.
[0137] As discussed above, ozone machine 116 is preferably operated
for .about.5-8 seconds for every .about.100 gallons contained in
circulating tank 112. However, ozone machine 116 may operate for up
to .about.15 seconds for every .about.100 gallons in circulating
tank 112. However, operation should not exceed .about.15 seconds
for every .about.100 gallons of water in circulating tank 112 in
order to prevent burning. This essentially saturates and shocks the
water. Typical ozone machine operations are between .about.0.08 to
.about.0.8 mm per liter, which is not sufficient to saturate/shock
the water. Exceeding .about.15 mm per liter results in essentially
"burning" the water as mentioned above, so that the water tastes as
if it were boiled. Burned water has an unnatural taste and, when
one drinks it, is so caustic that it can strip out saliva from the
mouth. It has utility in that it can "clear out" one's pipes and
has very powerful antibacterial effect in that it can strip
bacteria out that most people have a difficult time ridding from
their system. For example, iron bacteria in domestic wells is a
significant problem. Many believe that the only way to kill them is
with excessive chlorine, but that really does not do a complete
job. With this system, .about.12 seconds per 100 gallons of
ozonated water kills iron bacteria.
[0138] Magnetic structuring stage 120 is shown in FIG. 3A. Water
flows from pipe 160 into pipe 162 at location 200 and flows out at
location 204. Pipe 162 includes a series of magnetic donut rings
163. According to a preferred embodiment of the invention, other
magnet shapes might include north pole bar magnets or other
magnets. In this embodiment, there are preferably 14 such donut
rings 163a-163n evenly spaced over a distance "d" of approximately
7 feet, such that their central longitudinal axis are spaced apart
a distance "a" of .about.6.46''. Donut ring 163a preferably has a
magnetic field strength of .about.350 Gauss, while the magnetic
field strength of donut ring 163b linearly increases by a
difference of .about.91.66 Gauss to .about.441 Gauss. Further, the
magnetic field strength of each subsequent donut ring preferably
increases by the same amount linearly until it reaches a maximum
value of .about.900 Gauss. The magnetic field strength of donut
rings 163g and 163h are both preferably .about.900 Gauss. The
remaining magnets 163i through 163n preferably have magnetic field
strengths or flux that are also linearly decreased by .about.91
Gauss.
[0139] FIG. 3B is a graph showing the magnetic flux of the magnetic
donut rings of an exemplary magnetic structuring stage plotted
versus distance or position of the donut rings. In FIG. 3B, the
lowest value "LGauss" of magnetic flux for a donut ring is
.about.350 Gauss, while the highest value "HGauss" of magnetic flux
is .about.900 Gauss. However, HGauss value can be varied, for
example to .about.1200 Gauss. When HGauss is .about.1200 Gauss, the
water can become too clarifying to the colon. In another embodiment
of the invention, HGauss can be varied as high as .about.1800
Gauss. The value of HGauss depends on the flow rate of the water
through pipe 162. As HGauss is increased, the maximum flow rate is
preferably decreased. If the flow rate is too slow, the water
breaks down.
[0140] The purpose of magnetic structuring stage 120 is to
structure the water as it passes through the series of magnets 163.
The number and shape of magnets 163 can be varied. The flow rate is
controlled by the pressure of the water entering location 200 of
pipe 162, which pressure can vary anywhere from .about.22 psi up to
.about.30 psi. At .about.31 psi, there is a break over point. Water
output at location 204 is considered structured water. When HGauss
is .about.1200 Gauss, the water can hold more oxygen. The flow rate
of the water preferably increases as the value of HGauss is
increased in order to maintain equilibrium pressure/gauss.
[0141] FIG. 4A is a block diagram of an oxygen/water combining
system, according to one embodiment of the present invention. Ozone
treated alkaline water input to holding tank 109 via pipe 105 is
then output from holding tank 109 to oxygen/water combining system
113 via pipe 111. A pump 523 and pressure gauge 519 are preferably
provided on pipe 111 to control water flow.
[0142] Oxygen/water combining system 113 includes a structured
oxygen generator 600, which outputs structured oxygen via pipe 117,
which is combined and coupled to pipe 111 at valve 119. The ozone
treated alkaline water is mixed with the structured oxygen from
pipe 117 at valve 119, and both are then directed via pipe 118 to
diffusion chamber 115.
[0143] Structured oxygen generating machine 600 outputs high
pressure oxygen at pipe 117. For example, structured oxygen
generating machine 600 may output structured oxygen at up to
.about.300 PSI changing pressures change electron ring formulation
in molecule via pipe 117 before combining with the ozone treated
alkaline water in pipe 111. Pipe 111 may be, for example, an
.about.1 inch pipe.
[0144] The combination of water and oxygen in pipe 118 is then
sprayed into the diffusion chamber 115 via a pipe 504 in fluid
communication with a spray nozzle 503. The spray nozzle 503 has a
very small orifice, for example, less than .about.0.1 inches and
preferably less than .about.0.01 inches and more preferably
.about.0.0078 inches in diameter.
[0145] Diffusion chamber 115 includes a cylinder 507 capable of
generating a type of tornado or vortex 511 in diffusion chamber
115. Diffusion chamber 115 may be, for example, a modified water
filter rated to 250 psi with the top of the water filter replaced
with a small set of fittings, for example, .about.3/8 inch brass
fittings, that go through a .about.1 inch orifice, where a pipe for
the water filter would normally be located. At the end of pipe 504
is spray nozzle 503. Spray nozzle 503 may be -1/4 inch in diameter
and preferably has a spray fan which is designed to have a spray
fan angle that creates a strong vortex of the oxygen-water
combination in chamber 115. The resulting spray fan angle is
preferably .about.15.degree.. The oxygen-water combination at the
input of pipe 504 is preferably under a pressure of .about.60
PSI.
[0146] The tornado 511 is essentially a clockwise vortex that is
created in cylinder 507. The tornado 511 has a cream-like
appearance due to the fine oxygen bubbles. That is, the tornado 511
is essentially white because all of the oxygen is pulled into the
center of the vortex. The width of the tornado or vortex 511 is
preferably .about.3/4 inch and extends all the way to the bottom of
the preferably 18'' to 24'' cylinder 507. At the bottom of cylinder
507 is a pressure escape valve 513 which is coupled to a pipe 515A
which, in a preferred embodiment, is .about.1/2 inch in diameter.
The pipe 515A which is coupled to holding tank 109. Pipe 515B also
couples diffusion chamber 115 to holding tank 109. Pipe 25 connects
oxygen/water combining system 113 to cone system 121, with a
pressure gauge 25A and cut off valve 25B (See FIG. 1A) provided on
pipe 25 to control water flow. Pressure escape valve 513 and pipe
515A provide pressure relief for the system.
[0147] Oxygen is mixed with water at location 119. It is desirable
to saturate the water with oxygen so that there is an abundance of
oxygen. Because there, is a saturation of oxygen, it can actually
add oxygen to the water rather than pull oxygen out of the
water.
[0148] FIG. 4B is a flow chart of an oxygen/water combining method,
according to one embodiment of the present invention, performed by
the oxygen/water combining system 113. Step S531 involves receiving
ozone treated alkaline water via pipe 111. Step S533 involves
mixing oxygen with ozone treated alkaline water at valve 119. Step
S535 involves forcing the mixture of oxygen and ozone treated
alkaline water through spray nozzle 503 in diffusion chamber 115 to
create tornado/vortex 511. Step S537 involves outputting oxygen
enriched structured water from diffusion chamber 115. Step S539
involves outputting the oxygen enriched structured water from
oxygen/water combining system 113 via pipe 25.
[0149] FIG. 5A is a block diagram of a structured oxygen generating
machine 600 according to one embodiment of the present invention.
Structured oxygen generating machine 600 includes a compressor 604,
which is coupled via a pipe 608 to an oxygen generator 612.
Compressor 604 may be, for example, a .about.25 horsepower
compressor which outputs refrigerated and cleaned air at .about.250
PSI to oxygen generator 612. Oxygen generator 612 may be, for
example, an OGS oxygen generator. Oxygen generator 612 outputs
oxygen via a pipe 614 at, for example, .about.70 PSI to an oxygen
storage tank 616. Oxygen storage tank 616 in turn outputs oxygen at
high pressure (up to .about.300 PSI) through a high pressure pipe
620 to an oxygen enhancer 622. The oxygen is then directed to a
valve 624, which in turn directs the oxygen through either a first
magnetic structuring stage 628 or a second magnetic structuring
stage 632. When valve 624 is in a first position, oxygen output
from oxygen enhancer 622 passes through pipe 626 to first magnetic
structuring stage 628, shown in more detail in FIG. 6A. That is,
oxygen from oxygen enhancer 622 is input to first magnetic
structuring stage 628 via pipe 626 and, after passing through first
magnetic structuring stage 628, is output through pipe 631 to pipe
117 as structured oxygen. When valve 624 is in a second position,
oxygen from oxygen enhancer 622 passes through pipe 630 to the
second magnetic structuring stage 632, shown in more detail in FIG.
6B. That is, oxygen from oxygen enhancer 622 is input to second
magnetic structuring stage 632 via pipe 630 and is output via pipe
634 to pipe 117 as structured oxygen.
[0150] FIG. 5B is a flow chart of a method for producing structured
oxygen, according to one embodiment of the present invention. At
step S670, refrigerated and cleaned air is input to the oxygen
generator 612 under pressure. Oxygen generator 612, in turn,
outputs highly pressurized oxygen to oxygen storage tank 616 via
pipe 614 at step S674. At step S678, highly pressurized oxygen is
input to either first magnetic structuring stage 628 or second
magnetic structuring stage 632. At step S682, magnetically
structured oxygen is output from either the first magnetic
structuring stage 628 or the second magnetic structuring stage
632.
[0151] FIG. 5C is a longitudinal cross sectional view of the oxygen
enhancer 622 shown in FIG. 5A. The oxygen enhancer 622 preferably
has a substantially tubular body portion 6200, and is preferably
formed of a non-conductive material, such as, for example, high
pressure plastic. In one embodiment of the present invention, the
body portion 6200 may be between 14 and 17 inches long, and
approximately 3 inches in diameter. However, other dimensions for
the body portion 6200 may also be used. Ends of the body portion
6200 are preferably tapered so as to form an inlet 6210 and an
outlet 6220, which accommodate incoming and outgoing pipes 6215 and
6225, respectively. In one embodiment of the present invention, the
incoming and outgoing pipes 6215 and 6225 preferably have a 1/2
inch diameter, and some length thereof (e.g., 1/2 inch) may extend
into the body portion 6200. However, other diameters may also be
used.
[0152] Ring type devices 6230 and 6240, such as, for example, a
washer, are preferably positioned at the inlet 6210 and outlet 6220
to secure and properly align the pipes 6215 and 6225, respectively,
in place. The body portion 6200 are preferably filled with a
filtering material 6250, such as, for example, carbon, to scrub the
oxygen processed therethrough and absorb any contaminants that may
be present. The carbon chips 6250 may vary in size, and preferably
fall within an average size of between 1/8 and 1/32 inch. Carbon
creates a pure, clean oxygen that is readily accepted into the
water.
[0153] First and second mesh screens 6270 and 6280, respectively,
are preferably positioned in the body portion 6200 as shown in FIG.
5C, preferably with a void 6290 formed therebetween. The screens
6270 and 6280 may be made of any type of suitable metallic
material, such as silver, platinum or gold. In one embodiment of
the present invention, the screens 6270 and 6280 are preferably
made of a gold mesh material. However, other materials, such as,
for example, copper and brass, could also be used. The mesh size of
the screens 6270 and 6280 may also be varied. In one embodiment of
the present invention, the mesh size may preferably fall within a
range of between 150 and 200 microns, and is most preferably 200
microns.
[0154] A plurality of magnets are provided on each of the first and
second screens 6270 and 6280, with a first set of magnets 6275
preferably provided on a surface of the first screen 6270 facing
the inlet 6210, and a second set of magnets 6285 preferably
provided on a surface of the second screen 6280 facing the outlet
6220. Wires 6260, preferably made of a conductive material, such
as, for example, copper, extend from the first set of magnets 6275
to the inlet ring 6230, and from the second set of magnets 6285 to
the outlet ring 6240. The wires 6260 may be attached to the rings
6230 and 6240 by any suitable means such as, for example,
soldering.
[0155] A front view of an exemplary mesh screen 6300 is shown in
FIG. 5D. This exemplary mesh screen 6300 is shown with nine magnets
attached thereto, with a center magnet 6310 being preferably
slightly larger than surrounding magnets 6320. However, other
numbers of magnets, relative sizes, strengths, and arrangements on
the mesh screen 6300 may also be used. The magnets may be made of
any appropriate magnetic material. In one embodiment of the present
invention, the magnets are preferably button magnets, and most
preferably germanium button magnets, that are less than 1/2 inch in
diameter, and preferably 3/8 inch in diameter, and with a strength
of between 300 and 550 Gauss. Based on this type of magnet
arrangement on each of the first and second screens 6270 and 6280
shown in FIG. 5C, an appropriate width for the void 6290 is
approximately 1/2 inch. However, the number, arrangement, and
strength of the magnets may be varied, and an appropriate width of
the void 6290 may be determined based on the resulting strength of
the magnetic flux produced by the magnets.
[0156] In FIG. 5C, the first set of magnets 6275 is preferably
oriented with a north side 6276 facing the inlet 6210, and a south
side 6277 adjacent the first screen 6270, while the second set of
magnets 6285 is preferably oriented with a north side 6286 facing
the outlet 6220, and a south side 6287 adjacent the second screen
6280. This opposing polarity arrangement causes the oxygen to
"snap" as it passes through the void 6290, thus initiating the
structuring process by aligning and preparing the oxygen for
further structuring as it subsequently passes through either the
first or second structuring stages 628 or 632.
[0157] FIGS. 5E and 5F are front and side views, respectively, of a
ring 6291 which is preferably positioned within the void 6290. The
ring 6291 preferably includes a plurality of magnets 6292
positioned along a circumference of the ring 6291, adhered to the
ring 6291 by any suitable means. In one embodiment of the present
invention, fourteen germanium magnets 6292 are preferably adhered
along a circumference of the ring 6291 with a silicone based
compound. In this embodiment, each of the magnets 6292 may be
between 1/2 and 3/8 inch in diameter, and each have a strength of
approximately 200 Gauss. However, it should be understood that many
other combinations of type, number, and strength of the magnets may
be used to provide a suitable effect. Similarly, a width W of the
ring 6291 may be varied based on a corresponding width of the void
6290 formed between the screens 6270 and 6280.
[0158] As shown in FIGS. 5E-5G, a south pole S of each of the
magnets 6292 is preferably flush with an outer circumference 6293
of the ring 6291, while a north pole N of each of the magnets 6292
preferably extends from an inner circumference 6294 of the ring
6291 and toward the center of the ring 6291. Accordingly, when
configured as such and positioned in the void 6290 formed between
the screens 6270 and 6280, the south poles S of the magnets 6292
and the outer circumference 6293 of the ring 6291 contacts an inner
surface of the body portion 6200, while the left and right faces
6295 and 6296, respectively, of the ring 6291 contact the screens
6270 and 6280, respectively. In one embodiment of the invention,
the width W of the ring 6291 is approximately 1/2 inch to match the
corresponding width of the void 6290.
[0159] FIG. 6A is a schematic side view of a first magnetic
structuring stage for a structured oxygen generating machine,
according to one embodiment of the present invention. First
magnetic structuring stage 628 includes N donut magnets 1, 2, 3 . .
. N all arranged along pipe 626. Each of the donut magnets
1.about.N preferably has a strength of up to .about.3,300 Gauss.
The spacing between central longitudinal axes of the donut magnets
1 and 2 of first magnetic structuring stage 628 is preferably
.about.2 inches, and gradually increases to the middle 636 of first
magnetic structuring stage 628 at which point the spacing is
preferably .about.12 inches, and then the spacing between the
subsequent donut magnets decreases until the spacing between
central longitudinal axes of donut magnets N-1 and N is preferably
.about.2 inches. The middle 636 of first magnetic structuring stage
628 is preferably located .about.4.5 feet from each end of the
first magnetic structuring stage 628.
[0160] Alternatively, as discussed above, oxygen can be directed by
the valve 624 to the second magnetic structuring stage 632. FIG. 6B
is a schematic side view of the second magnetic structure stage for
a structured oxygen generating machine, in accordance with one
embodiment of the present invention. In this embodiment, there are
M central longitudinal axes of donut magnets which are spaced apart
distances D1, D2 . . . D.sub.M, where distances D.sub.i all
represent a Fibonacci sequence in inches. Hence, D.sub.i=1, 1, 2,
3, 5, 8, 13, . . . , whereby D.sub.i=D.sub.j-2+D.sub.j-1. In a
preferred embodiment, M is an integer between 1 and 21.
[0161] The structured oxygen, which is output from either the first
magnetic structuring stage 628 or the second magnetic structuring
stage 632, may be used to enrich water with oxygen according to
processes described herein. When the structured oxygen output from
first magnetic structuring stage 628 is mixed with properly
prepared water, the resulting water may provide energy to the
person or mammal that ingests the water. On the other hand,
structured oxygen output from second magnetic structuring stage
632, when used to enrich water, yields oxygen enriched water which
may produce a sedating effect for people or mammals that ingest the
oxygen enriched water.
[0162] FIG. 7A is a block diagram of a cone system, in accordance
with one embodiment of the present invention. Combined oxygen/water
is input via pipe 25 to cone system 121. A medical grade oxygen
machine 803 is coupled to pipe 25 via a pipe 805 at a valve 807.
Medical grade oxygen is output from the medical grade oxygen
machine 803 and mixed with the combined oxygen/water from the
system 10 at valve 807, and together are directed via a pipe 523 to
a series of cones 809. The series of cones 809 are shown in FIG. 7A
to be 6 cones 811, 813, 815, 817, 819 and 821, according to one
embodiment of the present invention. However, the number of cones
in the series of cones 809 can vary from 1 to N where N can be as
high as 24. The combined water/oxygen from system 10 and the
medical grade oxygen 803 are mixed by each of cones 811 through
821, which individually spin the combination, and output a
resulting spun water via pipe 27. In this embodiment, cone 811 is
coupled to cone 813 by a pipe 812, cone 813 is coupled to cone 815
by a pipe 814, cone 815 is coupled to cone 817 by a pipe 816, cone
817 is coupled to cone 819 by a pipe 818, and cone 819 is coupled
to cone 821 by a pipe 820.
[0163] FIG. 7B is a schematic side view of an exemplary cone 811,
and FIG. 7C is a schematic top view of the exemplary cone 811.
Referring to FIG. 7B, pipe 523 is coupled to a tube 831, for
example, a double-bent tube, near the top of cone 811. In this
embodiment, tube 831 is preferably a crystal tube. Tube 831
preferably includes two .about.90.degree. bends 833 and 835. Bends
833 and 835 are preferably -90.degree., but can vary by plus or
minus 45.degree.. Also, bends 833 and 835 are preferably configured
so as to impart a clockwise spin 837 in cone 811. The combination
of oxygen and water input to tube 831 is under high pressure of at
least .about.30 PSI and more preferably of at least .about.34 PSI
in order to create clockwise spin 837 inc cone 811. Pipe 812 is
coupled to cone 813 in the same manner as pipe 523 is coupled to
cone 811, and this is also true for cones 813 through 821 as
well.
[0164] Clockwise spin vortex 837 of the oxygen/water combination
will be referred to herein as a clockwise vortex spin 837. The
ratio of the oxygen from medical grade oxygen machine 803 and the
oxygen/water combination, together with the water pressure at tube
831, determines the efficiency of the mixing of oxygen with water
at cone 811, as well as the rest of cones 813-821. Lines 841 in
vortex 837 disappear if oxygen from medical grade oxygen machine
803 is turned off. That is, clockwise vortex spin 837 remains but
lines 841 disappear.
[0165] In the embodiment discussed above, the inner diameter of
tube 523 is preferably .about.1/4'' and the outer diameter is
preferably .about.1/2'', the inner diameter of tube 831 is
preferably .about.1/8'' and the outer diameter is preferably
.about.1/4''. The tube 831 is preferably .about.1 3/4'' long and
preferably extends to a position .about.3/8'' from the edge of cone
811, and is preferably attached to cone 811 by, for example, a
solder joint 811A. Further, cone 811 preferably has a diameter
D.sub.i at a top portion of .about.6'' and a diameter D.sub.b at a
bottom portion of .about.1/8''.
[0166] FIG. 7D is a flow chart of a method for spinning water with
oxygen using a cone system, according to one embodiment of the
present invention. Step S861 involves receiving the oxygen/water
combination. Step S863 involves combining the oxygen/water
combination with medical grade oxygen. Step S865 involves inputting
the combination of oxygen/water and the medical grade oxygen into
cone series 809. Finally, step S867 involves outputting spun water
as super-oxygenated and structured water, with its negative ORP
further enhanced and locked into the water.
[0167] FIG. 8A is a schematic side view and FIG. 8B is a schematic
top view of a coil system, according to one embodiment of the
present invention. Coil system 123 includes a coil 871 with an
outer diameter D. In this embodiment, coil 871 is preferably a
crystal coil. The outer diameter D of coil 871 can vary from
.about.4'' to .about.12'', and is preferably between .about.5'' and
.about.9'', and more preferably .about.7 inches. Pipe 27 is coupled
to tube 871 to form a bend 875 with an angle between
.about.45.degree. and .about.130.degree. and preferably between
.about.65.degree. and .about.95.degree. and more preferably
.about.90.degree.. In particular, pipe 27 is coupled to tube 871 to
form bend 875 and water flows through pipe 27 until it reaches bend
875 at which point it is abruptly redirected to the right to begin
a clockwise flow down tube 871 until it is output at pipe 29, as
shown in FIG. 8A.
[0168] In this embodiment, tube 871 is preferably cylindrical with
a round cross-section. However, other shapes, such as octagonal,
hexagonal, or oval, for example, can also be used.
[0169] A crystal 881 is preferably arranged approximately in the
center of coil 871, as shown in FIG. 8A. The size of crystal 881 is
preferably 3'' or 12'', but is more preferably 7''. However, other
crystal sizes may be used. The crystal 881 is arranged in a
container 883, which may contain a tincture or solution 885. A
battery 887 is preferably coupled via a wire 889 to crystal 881 and
the other pole of battery 887 is preferably grounded in tincture or
solution 885 via a wire 891. As the water travels in a clockwise
pattern down coil 871 it cuts through magnetic flux lines 893
created by the battery 887 and crystal 889 combination. The right
hand or clockwise flow of the water pulls electrons into its orbit.
If coil 871 is reversed, so as to provide a counterclockwise flow
or a left hand spin of the water, then the left hand spin throws
electrons out of the orbit. The water resulting from a left hand
spin is beneficial for a short time because of detoxifying effects
in the body. Independent of crystal 881, a motion of the water in
either a clockwise or counterclockwise fashion creates an
electromagnetic field which can be measured, such as any charged
particle in motion would create an electromagnetic field. In this
embodiment, crystal 881 is preferably a vogel crystal. Solution 885
may contain herbs or any substance depending on the tint for the
water. By placing different substances in solution 885 or by
changing solution 885, water output from pipe 29 can be tuned to
that particular substance or solution. "Tune" can refer to the
modification of the structure, character and/or property of the
water.
[0170] Crystal 881 oscillates at a particular resonance frequency,
which can modify the water. These frequencies can vary from
.about.5 to .about.9 Hz, and preferably from .about.6 to .about.8
Hz, and more preferably from .about.6.8 to .about.7.8 Hz, and even
more preferably from .about.7.2 to .about.7.8 Hz.
[0171] FIG. 8C is a flow chart of a method performed by the coil
system of FIGS. 8A-8B. In particular, FIG. 8C shows step S893,
which involves creating a magnetic flux, and step S895, which
involves passing water in a spiral fashion through the magnetic
flux. The magnetic flux is preferably created using a crystal, as
discussed with respect to FIG. 8A. Also, as water is passed in a
spiral fashion, it can be passed in a clockwise spiral fashion
through the magnetic flux in order to maintain free electrons in
the water or in a counterclockwise fashion in order to give off
electrons from the water.
[0172] FIGS. 9A and 9C are, respectively, schematic top and side
views of a multi-coil system, according to one embodiment of the
present invention. Multi-coil system 127 preferably includes coil
sets 901, 903, 905, and 907. Coil sets 901 and 907 are preferably
single coils, while coil sets 903 and 905 preferably contain inner
coils 903a and 905a, respectively, and outer coils 903b and 905b,
respectively.
[0173] Super-oxygenated and structured water mixed with structured
ozone is input via pipe 35 to multi-coil system 127. A series of
magnets 912 may be optionally placed on pipe 35 prior to entry into
multi-coil system 127. These magnets can be any shape, but are
preferably donut magnets and preferably north field magnets
surrounding or placed directly on the pipe 35.
[0174] As shown in FIG. 9A, coil set 901 is coupled to coil set 905
via a pipe 914, coil set 905 is coupled to coil set 907 via pipe
916, and coil set 907 is coupled to coil set 903 via pipe 918. In
this embodiment, water preferably enters coil set or coil 901 at a
top portion, spirals down to a bottom portion of coil 901 and then
passes via pipe 914 to coil set 905. At coil set 905, water
preferably enters a bottom portion of inner coil 905a and spirals
up against gravity to a top portion of inner coil 905a. The water
then passes into outer coil 905b and spirals down outer coil 905b
to a bottom portion, where it exits coil set 905 via pipe 916. The
water then preferably passes into a top portion of coil set or coil
907 and spirals downward to a bottom portion, where it exits coil
907 via pipe 918. The water next preferably enters coil set 903 at
a bottom portion of inner coil 903a, spirals up (against gravity)
to a top portion of inner coil 903a, where it passes into outer
coil 903b before spiraling downward to a bottom portion of 903b,
where it exits coil set 903 and multi-coil system 127 via pipe 37.
The super-oxygenated, tuned and structured water is then directed
to holding tank 109 via pipe 37.
[0175] As shown in FIG. 9C, multi-coil system 127 includes an outer
box 941 and an inner box 943 with mica 945 contained in between
inner box 943 and outer box 941. Coil sets 901-907 are preferably
between .about.5'' and .about.17'' inches wide and preferably
between .about.14'' and .about.33 inches long, and more preferably
.about.7 inches wide and .about.17 inches long. Inner coils 903a
and 905a preferably have a diameter in the range of .about.2'' to
.about.9'', and more preferably between .about.3'' and .about.5'',
and most preferably ''3''.
[0176] FIG. 9B is a schematic side view of coil set 905 of FIG. 9A.
Coil set 905, includes outer coil 905b and inner coil 905a. As
viewed from the top, the water spirals up the inner coil 905a in a
clockwise fashion until it reaches a top portion and then spirals
down the outer coil 905b where it exits the coil system 905. Inner
coil 905a is preferably supported by one or more supports 1070A,
preferably two dowel rods, and the outer coil 905b is preferably
supported by one or more supports 1070B, preferably a plurality of
dowel rods. The supports 1070A and 1070B are preferably connected
to coils 905a and 905b using plastic ties.
[0177] As shown in FIGS. 9D and 9E, the various pipes are connected
to the various coils via a tube, preferably with a bend. In this
embodiment, the tube is a glass tube with an .about.90.degree.
bend. As can be seen in FIG. 9B, a crystal 923 may be placed at a
base of the coil set 905. Crystal 923 is preferably a double
terminated quartz crystal, but is not limited to clear quartz. The
crystals are centered at the base and extend up inside the coil.
Extending the crystal further up into the coil reduces the effects.
Coil set 903 also has an arrangement like that shown in FIG. 9B
with respect to the coil set 905. Each coil set 903, 905, and 907
also includes a crystal arranged as shown in FIG. 9B.
[0178] As shown in FIG. 9C, magnets 912 may be arranged on pipe 35
prior to entry into multi-coil system 127, and serve to cancel
frequencies that have been input or are otherwise contained in the
water prior to input to multi-coil system 127. Although multi-coil
system 127 in this embodiment is shown with four coil sets, it can
contain one, two, three or more than four coil sets, with various
combinations of single and double coil sets. The inner diameter of
the inner and outer coils for coil sets 901-907 is preferably
.about. 5/16 inches. The coils for coil sets 901-907 are preferably
made of crystal and not pyrex. Crystal 923, as well as the crystals
for the other three coil sets, preferably have dimensions of
.about.17''.times..about.18'' to .about.3''.times..about.1'', and
more preferably .about.8-1/2 inches long and .about.3-1/2 inches
across double terminated.
[0179] FIG. 9F is a flow chart of a method performed by the
multi-coil system of FIGS. 9A-9E. Step S951 involves inputting
water and structured ozone into a top portion of a first coil set
or coil arranged in a first magnetic flux. Step S953 involves
passing the water/ozone combination clockwise down the first coil
set. Step S955 involves coupling the water/ozone combination into
the bottom of an inner coil of a second coil set arranged in a
second magnetic flux. Step S957 involves passing the water/ozone
combination clockwise up the inner coil of the second coil set.
Step S959 involves coupling the water/ozone combination into the
outer coil of the second coil set. Step S961 involves passing the
water/ozone combination clockwise down the outer coil of the second
coil set. Step S963 involves coupling the water/ozone combination
into a top portion of a third coil set arranged in a third magnetic
flux. Step S965 involves passing the water/ozone combination
clockwise down the third coil set. Step S967 involves coupling the
water/oxygen combination into a bottom portion of an inner coil of
a fourth coil set arranged in a fourth magnetic flux. Step S969
involves passing the water/ozone combination clockwise up the inner
coil of the fourth coil set. Step S971 involves coupling the
water/ozone combination into the outer coil of the fourth coil set.
Step S973 involves passing the water/ozone combination clockwise
down the outer coil of the fourth coil set. Step S975 involves
outputting super-oxygenated, tuned, and structured water.
[0180] FIG. 10A is a block diagram of a structured ozone machine,
according to one embodiment of the present invention. Structured
ozone machine 125 includes a medical grade oxygen source 746
coupled via a pipe 749 to a standard ozone machine 751. Medical
grade oxygen is output from medical grade oxygen source 746 to
ozone machine 751, which in turn produces ozone, which is output
via pipe 31. Pipe 31 may be, for example, .about.1/8 inch flex
tubing. Two low Gauss magnets 753 are arranged on pipe 31. Although
the two low Gauss magnets are shown in this embodiment, a single
low Gauss or more than two, including three, four, five, and so
forth, low Gauss magnets can be arranged along pipe 31. Where two
low Gauss magnets are arranged on pipe 31, they are preferably
spaced between 1/2'' and .about.3 inches apart, and more preferably
.about.1 inch apart. In this case, the low Gauss magnets 753 are
preferably magnets which are below -1,000 Gauss, and more
preferably below -500 Gauss and most preferably -200 Gauss
each.
[0181] FIG. 10B is a flow chart of a method performed by the
structured ozone machine of FIG. 10A to produce structured ozone.
Step S761 involves inputting medical grade oxygen into structured
ozone machine 125. Step S763 involves generating ozone using the
medical grade oxygen. Step S765 involves passing the ozone
generated from the medical grade oxygen through a magnetic flux to
yield structured ozone.
[0182] The water flow throughout the system is preferably
controlled to enhance the system's performance. That is, pipe
diameters and pressures at each point P in the system are
preferably configured to ensure proper functioning. Referring to
FIG. 1A, pipe diameters and water pressure at each point P are
preferably as follows.
[0183] At Point P1: Pipe diameter is preferably .about.1/2 to
.about.3 inch(es), more preferably .about.1 to .about.1 1/4
inch(es), most preferably .about.1 1/4 inches. Pressure is
preferably .about.17 to .about.36 psi, more preferably .about.18 to
.about.30 psi, most preferably .about.27 psi.
[0184] At Point P2: Pipe diameter is preferably .about.3/8 to
.about.1 1/2 inch(es), more preferably .about.3/4 to .about.1 1/4
inch(es), most preferably .about.1 inch. Pressure is preferably
.about.17 to .about.36 psi, more preferably .about.18 to .about.26
psi, most preferably .about.22 psi.
[0185] At Point P3: Pipe diameter is preferably .about.3/8 to
.about.1 1/2 inch(es), more preferably .about.3/4 to .about.1 1/4
inches(es), most preferably .about.1 inch. Pressure is preferably
.about.12 to .about.20 psi, more preferably .about.12 to .about.15
psi, most preferably .about.15 psi.
[0186] At Point P4: Pipe diameter is preferably .about.3/8 to
.about.1 1/4 inch(es), more preferably .about.1/2 to .about.1
inch(es), most preferably .about.1 inch. Pressure is preferably
.about.12 to .about.20 psi, more preferably .about.12 to .about.15
psi, most preferably .about.15 psi.
[0187] At Point P5: Pipe diameter is preferably .about.3/4 to
.about.1 1/2 inch(es), more preferably .about.3/4 to .about.1
inch(es), most preferably .about.1 inch. Pressure is preferably
.about.40 to .about.80 psi, more preferably .about.40 to .about.60
psi, most preferably .about.69 psi.
[0188] At Point P6: Pipe diameter is preferably .about.1/4 to
.about.3/4 inch(es), more preferably .about.1/4 to .about.3/8
inch(es), most preferably .about.3/8 inch. Flow rate should be
preferably 5 liters per minute. (Pressure preferably .about.22 to
.about.60 psi, more preferably .about.30 to .about.45 psi, most
preferably .about.44 psi.)
[0189] At Point P7: Pipe diameter is preferably .about.1/4 to
.about.1 1/4 inch(es), more preferably .about.1/2 to .about.3/4
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.50 to .about.75 psi, more preferably .about.49 to .about.69
psi, most preferably .about.69 psi.
[0190] At Point P8: Pipe diameter is preferably .about.1/4 to
.about.3/4 inch(es), more preferably .about.1/2 to .about.5/8
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.5 to .about.25 psi, more preferably .about.5 to .about.10
psi, most preferably .about.7-10 psi.
[0191] At Point P9: Pipe diameter is preferably .about.1/2 to
.about.1 inch(es), more preferably .about.5/8 to -3/4 inch(es),
most preferably .about.3/4 inch. Pressure is preferably .about.18
to .about.35 psi, more preferably .about.18 to .about.25 psi, most
preferably .about.25 psi.
[0192] At Point P10: Pipe diameter is preferably .about.1/4 to
.about.3/4 inch(es), more preferably .about.1/4 to .about.1/2
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.18 to .about.35 psi, more preferably .about.30 to .about.42
psi, most preferably .about.40-42 psi.
[0193] At Point P11: Pipe diameter is preferably .about.1/4 to
.about.3/4 inch(es), more preferably .about.3/8 to .about.1/2
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.15 to .about.50 psi, more preferably .about.20 to .about.40
psi, most preferably .about.34 psi.
[0194] At Point P12: Pipe diameter is preferably .about. 1/16 to
.about.1/4 inch(es), more preferably .about. 1/16 to .about.1/8
inch(es), most preferably .about.1/8 inch. Flow rate is preferably
1/8 liter per minute.
[0195] At Point P13: Pipe diameter is preferably .about. 1/16 to
3/4 inch(es), more preferably .about.3/8 to .about.1/2 inch(es),
most preferably .about.1/2 inch. Pressure is preferably .about.10
to .about.25 psi, more preferably .about.10 to .about.18 psi, most
preferably .about.15-18 psi.
[0196] At Point P14: Pipe diameter is preferably .about. 1/16 to
.about.3/4 inch(es), more preferably .about.3/8 to .about.1/2
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.15 to .about.35 psi, more preferably .about.18 to .about.22
psi, most preferably .about.22 psi.
[0197] At Point P15: Pipe diameter is preferably .about. 1/16 to
.about.3/4 inch(es), more preferably .about.3/8 to .about.1/2
inch(es), most preferably .about.1/2 inch. Pressure is preferably
.about.15 to .about.75 psi, more preferably .about.22 to .about.60
psi, most preferably .about.30-40 psi.
EXAMPLE 1
Heart Rate and Exercise Performance
[0198] The present example is provided to demonstrate the utility
of the present invention for maintaining and/or restoring a desired
physiological fluid oxygen level in an animal. In particular
aspects, the present example will also demonstrate the utility of
the present compositions for maintaining, and in some aspects
normalizing, a reduced oxygenated blood level in an animal
subsequent to a blood oxygen-lowering effect activity, such as what
typically occurs in an animal, such as a human, after an
oxygen-consuming activity, such as exercise. Changes in these
physiologically measurable parameters are typically attendant an
increase in physical activity, stress or other fatigue-inducing
event.
[0199] The parameters that were measured in the present study were
changes in subjects consuming the oxygen-enriched, microstructured
water preparations verses subjects consuming conventional bottled
water. The changes in these two subject populations were monitored
for changes in heart rate, changes in oxygen saturation, changes in
blood lactate, changes in oxygen consumption, and changes in
fatigue assessment by a patient in response to a defined exercise
regimen after having consumed a defined quantity of the
oxygen-enriched, structured and/or microstructured water, or after
consuming a conventional bottled water.
[0200] The present study was a randomized, double blind crossover
study. Subjects were recruited from training facilities in
Montreal. Subjects were tested on four different days during a
two-week period. The subjects comprised a group of males and
females of at least 18 years in age in good physical condition.
None of the test subjects had any history of serious chronic
disease. Each of the test subjects had been in physical training
during the previous year, training at least 2 times per week,
during the time preceding their participation in the present
study.
[0201] The test subjects were randomly assigned to a group to
receive the oxygen enriched, structured and microstructured water
preparation verses a preparation of conventional tap or bottled
water (Placebo).
[0202] The total duration of the study was 14 days, comprised of
four (4) evaluation visits. Each subject, depending on the group
assigned, was asked to drink 500 ml of the oxygen-enriched
structured and microstructured water or 500 ml of the bottled Santa
Fe municipal city water. Each subject was then asked to sit for 5
minutes. After 5 minutes, a baseline physiological set of
measurements were recorded for each subject. These measurements
included heart rate, blood pressure, blood oxygen, blood oxygen
saturation, and blood lactate.
[0203] Once recorded, the subject began a 5-minute warm-up on a
treadmill. After this warm-up period, the subject began a
multi-stage VO.sub.2-max test. Each subject then underwent a
standardized five-step exercise tolerance test to fatigue. During
this test, each subject was asked to consume 500 ml of the
oxygen-rich, microstructured water or bottled spring water,
according to the initial test group to which they were originally
assigned. (Total consumption by each test subject was between 1/2
and 3/4 liter).
[0204] The multi-stage VO.sub.2--max test commenced at a speed of
11.3 km/hr (7.02 miles/hr) and a slope of 2 degrees. The slope was
then progressively increased by 2 degrees every minute. At the end
of each stage, heart rate, blood pressure and blood oxygen
saturation were measured. Upon maximal exertion, VO.sub.2 max was
calculated and blood lactate was measured. A visual analog scale
was used to assess perceived fatigue (i.e., maximal exertion), at
the end of the VO2 max. For this determination, the subject was
asked to place an "X" on a 10 cm line indicating how tired they
felt at the end of the VO.sub.2 max test with one end of the line
indication no fatigue (0), and the other end indication exhaustion
(10). This routine was repeated with the same product 2 days later.
A third visit took place one week later when subjects were asked to
return to the gym.
[0205] Each subject then completed the same protocol of exercise a
second time, this time consuming the opposite product (i.e., Group
1--Bottled Santa Fe Municipal City Water (Placebo) consumed (1/2 to
3/4 liter) during Exercise Test Session 1; Group
1--Oxygen-enriched, Structured and Microstructured water (AGFW)
consumed (1/2 to 3/4 liter) during Exercise Test Session 2) (Group
2--Bottled Spring Water (placebo) consumed (1 Liter) during
Exercise Test Session 1 (1 Liter); Group 2--Oxygen-enriched,
Microstructured Water (AGFW) during Exercise Test Session2).
[0206] As demonstrated in the data presented at Tables 1, 2 and 3,
the performance parameters that were assessed and compared in
response to consumption of the oxygen-enriched, microstructured
water preparations were heart rate, oxygen saturation, blood
lactate, and oxygen consumption and fatigue assessment. As used in
this study and others described throughout this application,
"fatigue" is defined as the length of physical exertion needed for
the subject to assess subjectively an exhaustion level of at least
7 on a scale of 0 to 10.
[0207] Table b 1 presents the data collected from the subjects at a
first visit and at a second visit. Table 2 presents the change
demonstrated in each of the performance parameters. Table 3
presents an analysis of the differences between the changes
observed in each of the performance parameters examined.
TABLE-US-00001 TABLE 1 Exercise Performance Parameters by Visit and
Treatment Period Visit 1 Visit 2 Parameter: AGFW Placebo P-Value
AGFW Placebo P-Value Change in Mean (SD) 86.93 76.00 0.001 76.25
75.76 0.999 Heart Rate (18.15) (15.60) (14.70) (13.64) 95% C.I.
81.38, 92.49 71.22, 80.78 71.76, 71.60, 80.75 79.96 Change in Mean
(SD) -2.05 (2.53) -1.90 (2.32) 0.377 -2.22 -1.85 (2.37) 0.198
Oxygen (1.67) Saturation 95% C.I. -2.82, -1.27 -2.61, -1.19 -2.73,
-1.71 -2.58, -1.13 (%) Blood Lactate Mean (SD) 11.30 (3.64) 9.43
(3.52) 0.007 10.29 9.44 (4.05) 0.125 (3.09) 95% C.I. 10.19, 12.41
8.35, 10.50 9.34, 8.20, 10.68 11.23 Calculated Mean (SD) 66.37
(4.23) 66.05 (4.47) 0.407 66.39 66.59 (4.92) 0.750 Oxygen (4.50)
Consumption 95% C.I. 65.07, 67.66 64.68, 67.42 65.01, 65.08, 67.77
68.09 Fatigue Mean (SD) 11.94 (2.36) 11.94 (1.89) 0.539 11.94 11.82
(2.17) 0.744 Assessment (2.25) 95% C.I. 11.18, 12.66 11.36, 12.52
11.25, 11.16, 12.63 12.49
[0208] TABLE-US-00002 TABLE 2 Change in Exercise Performance
Parameters between Visits by Treatment Period AGFW Placebo P-Value
P-Value P-Value Within Within Between Parameter: Estimate Treatment
Estimate Treatment Treatment Change in Mean (SD) -10.68 0.932 -0.22
(13.17) 0.081 0.002 Heart Rate (16.11) 95% C.I. -15.61, -5.75
-4.25, 3.81 Change in Mean (SD) -0.17 (2.13) 0.067 0.05 (2.72)
0.070 0.519 Oxygen 95% C.I. -0.83, 0.48 -0.78, 0.88 Saturation (%)
Blood Lactate Mean (SD) -1.01 (4.08) 0.604 0.01 (3.89) 0.814 0.241
95% C.I. -2.26, 0.23 -1.18, 1.20 Calculated Mean (SD) 0.02 (2.41)
0.040 0.54 (2.51) 0.001 0.267 Oxygen 95% C.I. -0.71, 0.76 -0.23,
1.31 Consumption Fatigue Mean (SD) 0.00 (2.80) 0.342 -0.12 (2.19)
0.852 0.632 Assessment 95% C.I. -0.85, 0.86 -0.79, 0.55
[0209] TABLE-US-00003 TABLE 3 Difference in Change in Exercise
Performance Parameters between Treatment Periods Absolute Percent
P-Value P-Value Between Between Parameter: Estimate Treatment
Estimate Treatment Change in Heart Mean (SD) 10.46, 19.43 0.002
-0.65 (4.95) 0.038 Rate 95% C.I. 4.51, 16.41 -2.18, 0.89 Change in
Mean (SD) 0.22 (3.65) 0.519 -1.43 (1.74) 0.041 Oxygenation 95% C.I.
-0.89, 1.34 -2.04, -0.82 (%) Blood Lactate Mean (SD) 1.03 (4.75)
0.241 0.26 (8.17) 0.001 95% C.I. -0.43, 2.48 -2.24, 2.76 Calculated
Mean (SD) 0.51 (3.31) 0.267 -0.49 (1.84) 0.002 Oxygenation 95% C.I.
-0.50, 1.53 -1.23, 0.25 Fatigue Mean (SD) -0.12 (3.29) 0.632 -0.59
(4.79) 0.050 Assessment 95% C.I. -1.13, 0.89 -2.08, 0.90
[0210] Results:
[0211] The following efficacy outcome measures were defined to
assess the effect of consuming the oxygen-enriched water
preparations on exercise performance in the subject
participants.
[0212] For each parameter, the measurement at each visit was
determined as Pl1 (Placebo, first visit), Pl2 (placebo, visit 2),
AGFW1 (Oxygen-enriched water, visit 1), and AGFW2 (oxygen-enriched
water, visit 2).
[0213] For each subject, the following variables were
calculated:
[0214] CHANGE BETWEEN VISIT 2 AMD VISIT 1 FOR PLACEBO: DPl.sub.2-1:
Pl.sub.2-Pl.sub.1
[0215] CHANGE BETWEEN VISIT 2 AND VISIT 1 FOR OXYGEN-ENRICHED
PRODUCT (AGFW): DAGFW.sub.2-1: AGFW.sub.2-AGFW.sub.1
[0216] CHANGE BETWEEN AGFW AND PLACEBO:
DAGFW.sub.2-1-DP.sub.2-1
[0217] PERCENT CHANGE BETWEEN AGFW AND PLACEBO:
100%.times.PAGFW.sub.2-1-DPl.sub.2-1)/DPl.sub.2-1
[0218] The primary outcome variable for the studies was the latter
variable that measures the percent difference in the effect between
the oxygen-enriched water and the placebo.
[0219] Statistical Methods:
[0220] Given that each subject used both the placebo and the
oxygen-enriched preparations, and the fact that the distribution of
the study outcomes deviated from normal due to the small sample
size, the Kolmogorov-Smirnov paired, non-parametric tests were used
to assess the statistical significance of the different water
regimens. The null hypothesis tested was the mean change between
the oxygen-enriched preparations (AGFW) and the placebo was zero.
Two tailed significance testing was used. When the distribution of
the variable deviated from the normal, the non-parametric was
used.
[0221] Change in Heart Rate:
[0222] At visit one, a significant difference was observed in the
heart rate of patients consuming the oxygen-enriched, structured
and microstructured water, compared to subjects who consumed
conventional tap water. At visit 1, a significant difference was
observed in heart rate.
[0223] Heart rate (HR) is proportional to the work rate in physical
activities with anaerobic energy supply. The relationship between
HR and workload is highly reproducible for any individual (1). The
simple way of registering HR has made it the most widely used
estimate of metabolic strain in training or competition for many
types of exercise (2-4). The measurement of heart rate in this
study was based on the change in pulse between the beginning and
the end of the exercise test defined as 80% maximum capacity. The
reduction of change in heart rate during exercise until fatigue
indicates that subjects who consumed the oxygen-enriched water
increased their endurance by significantly reducing the increase of
pulse by 65%.
[0224] The mean (SD) percent change was 0.65 (4.95), indicating
that when subjects consumed the oxygen-enriched water, the change
in heart rate during exercise to fatigue was reduced by 65% when
compared to placebo.
EXAMPLE 2
Change on Oxygen Saturation
[0225] The present example demonstrates the utility of the present
compositions and methods for inhibiting and/or onset of fatigue in
a human. The maintenance of oxygen saturation levels (i.e.,
decreasing the change in oxygen saturation levels attendant
exercise) in response to exercise is also demonstrated.
[0226] Oxygen saturation measurements were taken during the
exercise periods. The change in oxygen saturation between beginning
of the exercise and the end was used for the determination of
effect on oxygen saturation.
[0227] When subjects consumed the oxygen-enriched water product,
the change in blood oxygen saturation after a period of exercise
was significantly less than the dramatic drop in blood oxygen
saturation demonstrated after exercise in subjects that consumed
the bottled Santa Fe municipal city water (placebo).
[0228] The results show that when the subjects used the
oxygen-enriched preparations, the drop in oxygen saturation was
less by a factor of 1.5 (150%), in comparison to the drop in oxygen
saturation demonstrated in subjects consuming the Santa Fe
Municipal City bottled water preparations (placebo). This effect is
statistically significant P=0.041).
EXAMPLE 3
Blood Lactate
[0229] The present example demonstrates the utility of the present
compositions and methods for inhibiting and/or reducing the
increase in levels of blood lactate attendant exercise in a human.
In addition, and because blood lactate level may be directly
correlated with lactic acid accumulation in muscle attendant
exercise, the present example also demonstrates the utility of the
presently described methods and compositions for reducing muscle
soreness, and for reducing lactic acid accumulation in muscle as
indicated by blood lactate levels. The present study demonstrates
that consumption of the defined oxygen enriched preparation
significantly inhibited (i.e., reduced) the typical increase in
blood lactate levels saturation typically attendant exercise.
[0230] Patients were treated and monitored as outlined in Example
1. Blood lactate levels were obtained from all subjects. The data
from these studies is presented in Tables 1, 2 and 3.
[0231] Blood Lactate:
[0232] Blood lactate levels were at least 89.95% lower in subjects
consuming the oxygen-enriched water preparations, compared to blood
lactate levels in subjects consuming the bottled water preparation
Placebo), after the defined exercise regimen. This difference is
statistically significant (P=0.010).
[0233] Lactic Acid:
[0234] Lactate in the blood can be correlated with the accumulation
level of lactic acid in muscle tissue; the present data also
provides indication that the consumption of the oxygen-enriched
water preparations as defined herein can significantly reduce
lactic acid accumulation in tissues. It is thus further expected
that the use of the oxygen-enriched water preparations as herein
defined can significantly reduce the muscle soreness/burning
typically attendant periods after extreme exercise.
EXAMPLE 4
Calculated Oxygen Consumption
[0235] The present example is presented to demonstrate the utility
of the present methods for reducing and/or inhibiting the
significant and sudden increase on oxygen consumption attendant
exercise n a human.
[0236] Subjects were treated according to the regimen outlined in
Example 1. The oxygen consumption data collected from the subjects
that consumed the oxygen-enriched microconstructed water (AGFW) or
the bottled spring water (Placebo) is presented at Tables 1, 2 and
3.
[0237] The study demonstrated that consumption of the defined
oxygen enriched preparation significantly inhibited (i.e., reduced)
the characteristic increase in oxygen consumption levels saturation
typically attendant exercise.
[0238] Over a period of three days of consumption the
oxygen-enriched water preparations, a much more static,
conservative and constant amount of oxygen consumption was achieved
by the body. This is contrasted by the significant increase in
oxygen consumption illustrated by the significant increase in
oxygen consumption. Oxygen consumption was reduced by 50%. This
change was also statistically significant (P=0.004).
EXAMPLE 5
Enhanced Endurance/Fatigue Onset Assessment
[0239] The present example is presented to demonstrate the utility
of the present methods and compositions for reducing and/or
inhibiting the onset of fatigue in response to exercise in a
human.
[0240] Subjects were treated according t the regimen outlined in
Example 1. The fatigue assessment data from the subjects that
consumed the oxygen-enriched microstructured water (AGFW) or the
bottled Santa Fe Municipal City water (Placebo) is presented at
Tables 1, 2 and 3.
[0241] The mean standard deviation (SD) percent change was 0.65
(4.95), indicating that when subjects consumed the oxygen enriched
preparations, the change in heart rate during exercise to fatigue
was reduced by 65% when compared to placebo.
[0242] A statistically significant difference with respect to
subjective assessment of fatigue by a factor of 59% in subjects
consuming the oxygen-enriched preparations. (P=0.04).
EXAMPLE 6
Increase in Blood Oxygen
[0243] The present example is presented to demonstrate the utility
of the present methods and compositions for increasing and/or
replenishing available oxygen in the blood stream by consuming the
oxygen-enriched microstructured water preparations.
[0244] The present studies were conducted on humans using a medical
oximeter. In these studies, it was demonstrated that consumption of
the oxygen-enriched, microstructered component containing water
compositions of the present invention greatly increased the
availability of oxygen in the bloodstream. Using the oximeter, it
is shown that a person's blood oxygen levels taken at high altitude
(over 5,000 feet) can be increased within two minutes of consuming
the enriched oxygen, microstructured water. The overall increase in
oxygen in the blood at high altitudes usually increases from three
(3) to six (6) points after drinking either ounces of the oxygen
enriched, microstructured water. A medical grade oximeter provides
an accurate analysis of blood oxygen levels that is not invasive to
the patient and that is immediately detectable. The accuracy of the
device is .+-.2%. The device is slipped over the top of, for
example, a finger, and allowed to moniter and take a reading of the
patient/subject both before and after consuming the appropriate
amount of the oxygen enriched, microstructured water.
[0245] The medical grade oximeter used in the present example
demonstrated a measurable increase in the blood hemoglobin levels
of the patient. These results demonstrate the utility of using the
presently disclosed methods and compositions for the treatment of a
variety of conditions associated and/or linked with low blood
oxygen, such as altitude sickness. In addition, it is anticipated
that the present compositions are also useful as a preferred
beverage for consumption by professional athletes and/or those
persons involved in any competitive sport, and provide for an
enhancement of the persons endurance and performance as a result of
the increase in available blood oxygen.
EXAMPLE 7
Bound Oxygen Stability in Open (Non-Pressurized) Conditions
[0246] The present example demonstrates that the oxygen-enriched
preparations herein are capable of retaining a higher concentration
and/or amount of oxygen under open-air (i.e., open container)
conditions. Absent the microstructured nature of the present
preparations, the oxygen concentration would decrease and
leak/evaporate away.
[0247] A WTW 300 DO meter was used to test and determine oxygen
content and stability in the oxygenated alkaline structured water
(this water was 6 months old). The oxygen content was tested at 76
ppm and tested every hour on the hour for three days. The water was
placed in a 4 inch open beaker in a warehouse that had no air
conditioning. Temperatures ranged from 74.degree. F. at night to
101.degree. F. during the day. Even after agitating the water in
the four inch wide beaker every hour after three days, the first
hour of the fourth day there was approximately 30 ppm of oxygen in
the water. When the water was subsequently boiled, frozen and
shaken, the water still was just as effective biologically even
though the oxygen was reduced to 30% of its original levels using a
DO meter.
[0248] The foregoing embodiments and advantages are merely
exemplary and are not to be construed as limiting the invention.
The present teaching can be readily applied to other types of
apparatuses. The description of the invention is intended to be
illustrative, and not to limit the scope of the claims. Many
alternatives, modifications, and variations will be apparent to
those skilled in the art. In the claims, means-plus-function
clauses are intended to cover the structures described herein as
performing the recited function and not only structural equivalents
but also equivalent structures.
* * * * *