U.S. patent application number 11/449424 was filed with the patent office on 2006-10-12 for animal food supplement compositions and methods of use.
Invention is credited to Gayle Dorothy Swain.
Application Number | 20060229905 11/449424 |
Document ID | / |
Family ID | 33437466 |
Filed Date | 2006-10-12 |
United States Patent
Application |
20060229905 |
Kind Code |
A1 |
Swain; Gayle Dorothy |
October 12, 2006 |
Animal food supplement compositions and methods of use
Abstract
An animal food supplement particularly useful in treating
gastrointestinal problems, such as colic. Psyllium husks are
provided in dry form for convenience of handling prior to feeding.
In example embodiments, psyllium husks are admixed with binding
material and the admixture is formed into pellets, crumbles,
mashes, or licks. Upon consumption by the animal, the psyllium
husks take up water from the moist environment of the animal's
gastrointestinal tract and form a gelatinous bolus that sweeps
through the gastrointestinal tract of the animal, clearing the
gastrointestinal tract of intestinal detritus, such as sand,
toxins, and microorganisms, which agglomerate with and/or are
carried away by the psyllium husk gel.
Inventors: |
Swain; Gayle Dorothy;
(Boise, ID) |
Correspondence
Address: |
TRASK BRITT
P.O. BOX 2550
SALT LAKE CITY
UT
84110
US
|
Family ID: |
33437466 |
Appl. No.: |
11/449424 |
Filed: |
June 7, 2006 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
|
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10636331 |
Aug 6, 2003 |
7067161 |
|
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11449424 |
Jun 7, 2006 |
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Current U.S.
Class: |
424/738 |
Current CPC
Class: |
A61P 1/00 20180101; A61K
36/68 20130101 |
Class at
Publication: |
705/001 |
International
Class: |
G06Q 99/00 20060101
G06Q099/00 |
Foreign Application Data
Date |
Code |
Application Number |
May 29, 2003 |
AU |
2003204441 |
Claims
1. A method of treating or preventing a gastrointestinal problem in
an animal, comprising administering to the animal a food supplement
composition comprising: psyllium husk material; and at least one
binding agent for binding the psyllium husk material in a desired
physical form.
2. The method according to claim 1, wherein the food supplement
composition comprises: between about 30 to 35 percent psyllium husk
material; less than about 8 percent protein; between about 7.5 to
10 percent lucerne; at least one binding agent binding the psyllium
husk material in a desired physical form; and a moisture content of
approximately 11 to 14 percent.
3. The method according to claim 2, wherein the food supplement
composition further comprises between about 0.001 to 70 percent
creatine.
4. The method according to claim 1, wherein the gastrointestinal
problem is colic.
5. A method of treating or preventing a gastrointestinal problem in
an animal, comprising administering to the animal a food supplement
composition comprising psyllium husk material and at least one
binding agent for binding the psyllium husk material in a desired
physical form according to the following schedule: (a) about 500 g
on a first day of treatment; (b) about 850 g on a second day of
treatment; (c) about 1000 g on a third day of treatment; (d) about
2000 g on a fourth day of treatment; and (e) about 2500 g on a
fifth day of treatment.
6. The method according to claim 5 further comprising repeating the
schedule about every ten weeks.
7. The method according to claim 5 wherein the animal is a
horse.
8. The method according to claim 5, wherein the food supplement
composition comprises: between about 30 to 35 percent psyllium husk
material; less than about 8 percent protein; between about 7.5 to
10 percent lucerne; at least one binding agent binding the psyllium
husk material in a desired physical form; and a moisture content of
approximately 11 to 14 percent.
9. The method according to claim 8, wherein the food supplement
composition further comprises between about 0.001 and 70 percent
creatine.
10. A method for eradicating rodents, comprising distributing in an
area where rodents are present a food supplement composition
comprising: psyllium husk material; and at least one binding agent
for binding the psyllium husk material in a desired physical
form.
11. A solid food supplement composition for a non-human animal,
comprising: between about 30 to 35 percent psyllium husk material;
less than about 8 percent protein; between about 7.5 to 10 percent
lucerne; at least one binding agent binding the psyllium husk
material in a desired physical form; creatine; and a moisture
content of approximately 11 to 14 percent.
12. The food supplement composition of claim 11, wherein the
creatine is present at from about 0.001 to 95 percent by
weight.
13. The food supplement composition of claim 11, wherein the food
supplement composition is sufficiently low in nutritional value so
as to avoid interference with or disruption of the diet of the
non-human animal ingesting the food supplement composition.
14. The food supplement composition of claim 11, further comprising
at least one grain by-product selected from the group consisting
essentially of oats, barley, maize, lupins, lupin hulls, bran,
canola meal, and soya meal.
15. The food supplement composition of claim 11, further comprising
hay.
16. The food supplement composition of claim 15, wherein the hay is
at least one of oaten, wheaten, and meadow hay.
17. The food supplement composition of claim 11, further comprising
at least one pharmaceutical composition.
18. The food supplement composition of claim 11, further comprising
at least one nutrient.
19. The food supplement composition of claim 18, wherein the at
least one nutrient is at least one of a vitamin and a mineral.
20. The food supplement composition of claim 11, wherein the
desired physical form is a pellet, a crumble, a mash, or a
lick.
21. The food supplement composition of claim 11, further comprising
a flavoring.
22. The food supplement composition of claim 11, wherein the
flavoring includes molasses.
23. A substantially hermetic package containing a solid food
supplement composition, the substantially hermetic package
containing an atmosphere having less oxygen than ambient air, the
solid food supplement composition comprising: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent for binding the psyllium husk material in a desired
physical form; creatine; and a moisture content of approximately 11
to 14 percent.
24. A method of increasing the amount of Bacteroides
thetaiotamicron in the gut of an animal, the method comprising:
feeding the animal a food composition comprising psyllium husk.
25. The method according to claim 24, further comprising
formulating the food composition to comprise: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent binding the psyllium husk material in a desired
physical form; and a moisture content of approximately 11 to 14
percent.
26. A method of decreasing the amount of organisms other than
Bacteroides thetaiotamicron in the gut of an animal, the method
comprising: feeding the animal a food composition comprising
psyllium husk.
27. The method according to claim 26, further comprising
formulating the food composition to comprise: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent binding the psyllium husk material in a desired
physical form; and a moisture content of approximately 11 to 14
percent.
28. A method of increasing the rate of growth during a growth
period in animal, the method comprising: feeding the animal a food
composition comprising psyllium husk.
29. The method according to claim 28, further comprising
formulating the food composition to comprise: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent binding the psyllium husk material in a desired
physical form; and a moisture content of approximately 11 to 14
percent.
30. The method according to claim 28 further comprising increasing
the growth rate of the animal by about 1% to about 200% when
compared to the normal growth rate.
31. A method of reducing the need for antibiotics to be given to an
animal, the method comprising: feeding the animal a food
composition comprising psyllium husk.
32. The method according to claim 31, further comprising
formulating the food composition to comprise: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent binding the psyllium husk material in a desired
physical form; and a moisture content of approximately 11 to 14
percent.
33. A method of optimizing an animal feeding regime of a food
composition comprising psyllium husk, the method comprising:
monitoring the bacterial content in the gut or feces of the animal;
and adjusting the amount of the food composition in the diet of the
animal; wherein the adjusting of the amount of the food composition
in the diet of the animal alters the bacterial content in the gut
or feces of the animal.
34. The method according to claim 33, further comprising
formulating the food composition to comprise: between about 30 to
35 percent psyllium husk material; less than about 8 percent
protein; between about 7.5 to 10 percent lucerne; at least one
binding agent binding the psyllium husk material in a desired
physical form; and a moisture content of approximately 11 to 14
percent.
35. The method according to claim 33, wherein adjusting the amount
of the food composition in the diet of the animal increases the
content of Bacteroides thetaiotamicron in the gut or feces of the
animal.
36. The method according to claim 33, wherein a wherein adjusting
the amount of the food composition in the diet of the animal
decreases the content of organisms other than Bacteroides
thetaiotamicron in the gut or feces of the animal.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation-in-part of U.S. patent
application Ser. No. 10/636,331, filed Aug. 6, 2003, which in turn
claims priority from AU200300020441, filed May 29, 2003, the entire
disclosure of each of which are incorporated by this reference.
BACKGROUND OF THE INVENTION
[0002] The present invention relates to animal food supplement
compositions and methods of using the same, the compositions being
particularly useful in relation to, but not limited to, treatment
of colic and other gastrointestinal problems in animals.
[0003] Animal healthcare is an important consideration in many
aspects of the economy, such as in food production, research,
education (e.g., in zoos) and animal competitions (e.g., horse
racing). Productivity, cost control and profitability in these
areas of the economy are improved when the health of the animals
involved is improved. Efficient and cost-effective animal
healthcare is especially important where a substantial investment
is required to raise animals to maturity, as is the case with
horses.
[0004] Animals frequently ingest sand, soil, and other extraneous
materials when they are grazing or feeding from a feed box that
contains such contaminants. Over time, deposits of these extraneous
materials accumulate in the digestive system of the animal, causing
colic. Colic generally refers to malfunction, swelling, infection,
or blockage in the gastrointestinal tract of an animal. As used
herein, the term "intestinal detritus" refers to the aforementioned
ingested sand, soil, and other extraneous materials accumulated in
the gastrointestinal tract of an animal.
[0005] Instances of colic are particularly distressing for the
animal and for the owner, because colic is frequently painful to
the animal and difficult to identify and treat. Though an owner may
try numerous treatments to relieve the animal's symptoms,
unfortunately, previously known treatments often prove ineffective
and, unfortunately, animals regularly die as a result of colic. For
example, approximately one in ten horses with colic die because no
effective treatment has been available in the past.
[0006] In economically significant animals such as horses, cattle,
swine, chickens, broilers, quail, pheasants, turkeys, ostrich,
emus, and other exotic birds, gastrointestinal problems such as
colic pose a major economic threat. As a result, means for reducing
the economic impact of colic, i.e., cost-effective treatments for
colic, are in great demand.
[0007] The present invention overcomes, at least in part, some of
the aforementioned disadvantages of prior art treatments for colic
and other gastrointestinal problems in animals.
BRIEF SUMMARY OF THE INVENTION
[0008] The present invention provides an animal food supplement
particularly useful in treating gastrointestinal problems, such as
colic, in horses, cattle, swine, chickens, broilers, quail,
pheasants, turkeys, ostrich, emus, and other exotic birds. Psyllium
husk is the only natural gelatinous and hygroscopic material that
is suitable for consumption by both humans and animals, so it is
abundantly available. According to the present invention, psyllium
husk may be provided in dry form for convenience of handling prior
to feeding. In currently preferred embodiments, psyllium husks may
be admixed with binding material having low moisture content, and
the admixture is formed into pellets, crumbles, mash, or licks.
Upon consumption by the animal, the psyllium husk material takes up
water from the moist environment of the animal's gastrointestinal
tract and forms a gelatinous bolus that sweeps through the animal's
gastrointestinal tract, clearing intestinal detritus, such as sand,
soil, toxins, and microorganisms, which agglomerates with and/or is
carried away by the psyllium husk gel.
[0009] A first aspect of the present invention includes an animal
food supplement composition including psyllium husk. The animal
food supplement may further comprise creatine.
[0010] A second aspect of the present invention includes a
pharmaceutical composition comprising an animal food supplement
composition as an active ingredient optionally admixed with a
pharmaceutically acceptable carrier, the animal food supplement
composition including psyllium husk.
[0011] A third aspect of the present invention includes a method of
using an animal food supplement composition for the preparation of
medicaments for the treatment of animal gastrointestinal problems,
such as horse colic, wherein the animal food supplement composition
includes psyllium husk.
[0012] A fourth aspect of the present invention includes a packaged
animal food supplement composition comprising a substantially
hermetic packaging material containing the animal food supplement
composition and an atmosphere with a reduced oxygen content in
comparison to ambient air.
[0013] A fifth aspect of the present invention includes a method of
using an animal food supplement composition including psyllium husk
for reducing the need for antibiotics to be given to an animal.
[0014] A sixth aspect of the present invention includes a method of
using an animal food supplement composition including psyllium husk
to increase the content of Bacteroides thetaiotamicron in the
gastrointestinal tract of an animal.
[0015] A seventh aspect of the invention includes a method of using
an animal food supplement composition including psyllium husk to
decrease the gastrointestinal content of organisms other than
Bacteroides thetaiotamicron in an animal.
[0016] An eighth aspect of the invention includes a method of
increasing the rate of growth during a growth period in an animal
by providing an animal food supplement composition including
psyllium husk to the animal before or during the growth period.
[0017] A ninth aspect of the invention includes methods of
optimizing a feeding regime including an animal food supplement
composition comprising psyllium husk, the method comprising
monitoring the bacterial content in the feces of an animal.
[0018] A tenth aspect of the invention includes a method of
eradicating rodents comprising distributing in a area where rodents
are present a food supplement composition comprising psyllium husk
material and at least one binding agent for binding the psyllium
husk material in a desired physical form.
[0019] The present invention advantageously may be incorporated in
the ordinary diet of an animal as a treatment for, or preventive
measure against, colic and other gastrointestinal problems. An
additional advantage of the present invention is that it requires
only the use of natural ingredients.
[0020] Further advantages of the present invention over the state
of the art include (but are not limited to) the provision of the
animal food supplement according to the invention in a pellet,
crumble, mash, or lick form that has a low nutritional value so as
to avoid interference with or disruption of the diet of the treated
animal and to provide a convenient means by which medication or
other dietary supplements, such as vitamins and minerals, may be
added to the animal's diet. Through the practice of the present
invention, an animal's gastrointestinal tract is cleansed of
indigestible matter and toxic deposits for, as appropriate, the
prevention and treatment of gastrointestinal problems and
improvement of the overall health and well-being of the animal, one
result of which is improved economic productivity associated with
the animal.
BRIEF DESCRIPTION OF THE SEVERAL VIEWS OF THE DRAWINGS
[0021] In the drawings, which illustrate what is currently
considered to be the best mode for carrying out the invention:
[0022] FIG. 1 is a graphical depiction of a pellet physical form of
the food supplement composition of the invention.
[0023] FIG. 2 is a graphical depiction of a crumble physical form
of the food supplement composition of the invention.
[0024] FIG. 3 is a graphical depiction of a mash physical form of
the food supplement composition of the invention;
[0025] FIG. 4 is a graphical depiction of a lick physical form of
the food supplement composition of the invention; and
[0026] FIG. 5 is a graphical depiction of a specialized package
containing the food supplement composition of the invention.
DETAILED DESCRIPTION OF THE INVENTION
[0027] The present invention makes beneficial use of the
hygroscopic properties of psyllium husks. Psyllium husks swell when
they come into contact with water and thus are difficult to handle
conveniently when mixed with conventional animal feeds that have a
high moisture content, such as molasses and water. Accordingly, it
is preferred to provide psyllium husks in dry form for convenience
in handling. Upon consumption by the animal, the psyllium husks
take up water from the moist environment of the animal's
gastrointestinal tract and form a gelatinous bolus that sweeps
through the gastrointestinal tract of the animal, clearing the
gastrointestinal tract of intestinal detritus, such as sand, soil,
toxins, and microorganisms, which agglomerate with and/or are
carried away by the psyllium husk gel.
[0028] However, certain animals, such as horses, will not
voluntarily eat dry, unbound psyllium husk material because it is
unpalatable. Thus, the mere addition of dry unbound psyllium husks
to a feed box is ineffective since the animal may never actually
consume the psyllium husks despite their inclusion in the feed box.
Accordingly, the present invention provides an animal food
supplement that is designed to be palatable to animals for which it
is intended, e.g., by using flavors, aromas and textures that
appeal to the animal to be treated. The selection of flavors,
aromas, and textures appropriate for a given subject, i.e., the
design of a palatable product, is well within the skill of the
ordinary artisan and is, therefore, not discussed further here.
[0029] To overcome problems associated with the hygroscopicity of
psyllium husks, the present invention provides an animal food
supplement prepared from psyllium husks mixed together with a
relatively low moisture content binding agent. Preferably, the
animal food supplement is extruded into pellet form (as depicted in
FIG. 1) for ease of inclusion into the animal's feed box and to
ensure consumption thereof by the animal. However, it is also
envisaged that the animal food supplement of the invention may be
manufactured in a crumble form (as depicted in FIG. 2), a mash form
(as depicted in FIG. 3), or an animal lick form (as depicted in
FIG. 4).
[0030] The animal food supplement of the present invention contains
from 0 to about 95 percent by weight of psyllium husks in seed,
powdered or granulated form, including particulate material
comprising stalk, flower and leaf fragments with up to 0 to about
75 percent impurities. It is currently preferred that the food
supplement contain about 50 percent psyllium husks. Most preferably
according to present beliefs, the food supplement should contain
about 30 to 35 percent psyllium husks.
[0031] The animal food supplement of the present invention may also
contain from 0 to about 95 percent grain by-products, including
oats, barley, maize, lupins, lupin hulls, mill mix, mill run,
pollard, bran, canola meal, soya meal in a rolled, crushed or
powdered form, or a mixture thereof; from 0 to about 95 percent
lucerne in either chaff, hay, fines or powder form, or a mixture
thereof; from 0 to about 95 percent oaten, wheaten or meadow hay in
chaff, fines or powder form, or a mixture thereof; and/or from 0 to
about 95 percent molasses, and, optionally, additional vitamins and
minerals.
[0032] The animal food supplement of the present invention may also
contain creatine. Creatine is known in the art, among other
benefits, to help increase muscle mass. Creatine may be present
from 0 to 95 perecnet by weight. Further, the animal food
supplement of the present invention may be formulated to contain
from about 1 mg to about 40,000 mg of creatine per serving.
[0033] To avoid interference with or disruption of the animal's
diet, the food supplement of the invention preferably contains less
than about 8 percent protein.
[0034] It is currently preferred that the moisture content of an
animal food supplement according to the invention be approximately
11 to 14 percent. It is also currently preferred that an animal
food supplement according to the invention contain between about
7.5 and 10 percent lucerne in either chaff, hay, fines or powder
form, or a mixture thereof.
[0035] Pellets of the animal food supplement of the invention are
prepared by rolling, crushing and/or powdering grain by-products
and other binding agents as described above to achieve a
substantially homogenously sized mixture. Psyllium husks are then
added to the mixture, whereupon the mixture is treated with steam
and extruded through dies, which may range, for example, from 2 to
10 mm in aperture size to form pellets.
[0036] The use of proper packaging of the food supplement of the
invention is also a significant consideration. If exposed to
ambient air, the flavor, aroma and texture of the supplement
degrade undesirably over time. However, vacuum packaging is not
suitable because the supplement is best preserved if it is allowed
to "breathe" without being exposed to ambient air. Thus, another
advantageous aspect of the invention is specialized packaging that
prevents or reduces the aforementioned degradation.
[0037] Referring to FIG. 5, the packaging according to the
invention is substantially hermetic, and a reduced oxygen content
atmosphere such as an inert gas, for example, nitrogen, may be
introduced into the package during filling thereof with the
supplement in an appropriate form (for example, pellets) to
displace ambient air present inside the package, providing a sealed
environment, generally indicated at 50, containing the supplement
51 and an atmosphere 52 including less oxygen than ambient air 53.
Thus, packaging is provided that allows the food supplement of the
invention to "breathe" the atmosphere within the package while
preventing or at least reducing the degradation caused by exposure
to ambient air. Currently preferred are 3-ply paper sacks, in which
one ply is a 40 .mu.m BOPP liner, supplied by Australian Multiwall
Bag Co. Pty. Ltd. (Murdoch, Australia).
[0038] In use, the animal food supplement composition may be
introduced in pellet form, for example, into the feed box of an
animal that is exhibiting symptoms of gastrointestinal problems,
such as colic. In an example treatment for an adult horse, a dose
of about 500 g of the composition is provided on the first day of
treatment, a dose of about 850 g of the composition is provided on
the second day of treatment, a dose of about 1000 g of the
composition is provided on the third day of treatment, a dose of
about 2000 g of the composition is provided on the fourth day of
treatment, and a final dose of 2500 g of the composition is
provided on the fifth day of treatment.
[0039] During administration of the food supplement of the present
invention, the animal must drink plenty of fresh water on a regular
basis, otherwise serious injury may result.
[0040] The food supplement of the present invention was tested
against a placebo in horses. The feces of the horses were monitored
for clearance of intestinal detritus, and x-ray imaging was also
used to monitor movement of material through the gastrointestinal
tracts of the horses. One group of horses was administered the food
supplement of the invention according to the above schedule, while
a control group was fed a placebo according to the same schedule.
All horses that received the food supplement of the invention
cleared accumulated intestinal detritus (sand) during the course of
treatment, while those in the placebo group either did not clear or
cleared very little intestinal detritus. Horses receiving the food
supplement of the invention passed as much as 1/4 gallon of sand in
feces in a 24-hour period during treatment.
[0041] In addition, it was also observed that the general health
and performance of the animals were improved after receiving the
food supplement of the present invention. After treatment, animals
were observed to excrete less undigested feed, the condition of
their coats improved, and even some inexplicable behavioral
problems were resolved. Further animals receiving the food
supplement of the present invention during growth phases
demonstrate greater than normal growth increases in mass. While not
intending to be bound to any particular theory of action, the
inventor believes that promotion of symbiotic bacteria in
conjunction with clearance of intestinal detritus and non-symbiotic
bacteria through administration of the food supplement of the
present invention is useful in promoting growth of the animals,
reducing the amount of antibiotics that need to be given to an
animal, and in treating not only colic, but also other problems
that may be related to gastrointestinal blockage and/or
accumulation, such as equine ulcers and founder.
[0042] There is only one symbiote presently known to colonize the
human gut--Bacteroides thetaiotamicron. This anaerobic organism is
thought to aid digestion thought breakdown of complex carbohydrates
into simpler molecules that can be taken up by the gut. Further, it
has been recently found that the goblet cells of the intestine,
which are normally thought to secrete mucus, secrete packets of
cytoplasm containing large numbers of mitochondria. It is currently
thought that these mitochondria aid in the creation of a permissive
anaerobic environment for Bacteroides thetaiotamicron through the
consumption of available oxygen in the gut. The mucus secreted by
the goblet cells (a glycoprotein similar to that found in the food
supplement of the present invention) may also be used to provide a
food source to the symbiotic bacteria population in the absence of
normal food. For this reason the glycoprotein present in the food
supplement of the present invention should not effect the growth,
and may even promote the growth, of the symbiotic bacteria. In
contrast, most other normal gut flora (e.g. E. coli) do not grow
well (or at all) when streaked across agar plates containing a
dilute solution of the food supplement of the present
invention.
[0043] In relation to the increased growth noted in immature
animals fed with the food supplement of the present invention, the
increased growth may be due to the promotion of the symbiotic
bacteria by 1) providing at least a neutral composition or possible
a food source for the symbiotic bacterium, or 2) removing or
preventing the growth of other flora allowing the symbiotic
bacteria to better compete for limited space and food sources. As
the symbiotic bacteria population rises, more of the symbiotic
bacteria are available for the breakdown of foodstuffs containing
complex carbohydrates providing to the animal more useful energy
per unit of food consumed, leading to better growth.
[0044] Research is ongoing to determine whether equine ulcers are
caused by bacteria, as are ulcers in humans. If so, the food
supplement of the present invention may be useful in preventing as
well as treating equine ulcers by clearing the equine gut of
bacterial deposits. Further, it is believed that founder (chronic
laminitis) can be caused by toxic accumulations in the caecum,
which kill off beneficial bacteria and damage the wall of the
caecum. The damaged tissue of the caecum diverts resources such as
glucose from the bloodstream as it heals, and founder is believed
to result from insufficient nutrient supply to the hoof Thus, the
present invention is likely useful in treating a variety of animal
health problems, as well as for promoting and maintaining general
gastrointestinal health in animals.
[0045] The food supplement of the present invention is useful in
many kinds of animals such as, for example, horses, cattle, swine,
cats, dogs, chickens, broilers, quail, pheasants, turkeys, ostrich,
emus, and other exotic birds. Of course, it is contemplated that
the number of days of treatment and the dosages applied to each of
these species will vary depending upon the size of the animal and
the severity of the symptoms that it exhibits. For example,
weanling and yearling horses may be fed at half the rate of an
adult horse, and miniature ponies may be administered a dose of one
third cup per day for five days. One of ordinary skill in the art
in the health care of a given animal will readily be able to
determine an appropriate dosage regimen. In general, it is
currently preferred to administer the food supplement of the
invention for five days with gradually increasing daily doses.
[0046] The above-mentioned treatment schedule, or one similar
thereto, may be repeated every ten weeks as a preventive treatment
against colic or other gastrointestinal problems.
[0047] In one example of an embodiment of the present invention, a
method of increasing the content of Bacteroides thetaiotamicron in
the gut of an animal is disclosed. The method comprises feeding to
the animal a food supplement according to the present invention.
The content Bacteroides thetaiotamicron in the gut of the animal
may be monitored using standard techniques. One examples of such
techniques includes, but is not limited to, assaying the number of
Bacteroides thetaiotamicron in a feces sample by spreading the
sample on agar plate containing components known to promote the
growth of Bacteroides thetaiotamicron and placing the agar plate in
an anaerobic environment. After a number of days, the Bacteroides
thetaiotamicron content may be determined by counting the number of
Bacteroides thetaiotamicron plaques that grow on the plates.
[0048] A further example of such techniques includes, but is not
limited to, performing Polymerase Chain Reaction (PCR) on a feces
sample using species specific promoters directed to Bacteroides
thetaiotamicron, and relating the number of copies produced to the
Bacteroides thetaiotamicron content in the feces sample.
[0049] In a further example embodiment of the present invention, a
method of decreasing, in an animal, the gastrointestinal content of
organisms other than Bacteroides thetaiotamicron. The method
comprises feeding to the animal a food supplement according to the
present invention. The content of organisms other than Bacteroides
thetaiotamicron in the gut of the animal may be monitored using
standard techniques. One examples of such techniques includes, but
is not limited to, assaying the number of organisms other than
Bacteroides thetaiotamicron in a feces sample by spreading the
sample on agar plate containing components known to promote the
growth of bacteria generally and placing the agar plate in an
environment known to promote the growth of bacteria. After a number
of days, the bacterial content may be determined by counting the
number of bacterial plaques that grow on the plates.
[0050] A further example of such techniques includes, but is not
limited to, performing PCR (Polymerase Chain Reaction) on a feces
sample using species specific promoters directed to bacteria other
than Bacteroides thetaiotamicron, and relating the number of copies
produced to the bacteria content in the feces sample.
[0051] In another example embodiment of the present invention, a
method of decreasing the need for antibiotics to be given to an
animal is disclosed. The method comprises feeding to the animal a
food supplement according to the present invention. The need for
antibiotics can be correlated to the bacterial content of organisms
other than Bacteroides thetaiotamicron in the gut of the animal.
The content of organisms other than Bacteroides thetaiotamicron in
the gut of the animal may be monitored using standard techniques.
One examples of such techniques includes, but is not limited to,
assaying the number of organisms other than Bacteroides
thetaiotamicron in a feces sample by spreading the sample on agar
plate containing components known to promote the growth of bacteria
generally and placing the agar plate in an environment known to
promote the growth of bacteria. After a number of days, the
bacterial content may be determined by counting the number of
bacterial plaques that grow on the plates.
[0052] A further example of such techniques includes, but is not
limited to, performing PCR on a feces sample using species specific
promoters directed to bacteria other than Bacteroides
thetaiotamicron, and relating the number of copies produced to the
bacteria content in the feces sample.
[0053] In a yet further example embodiment of the present
invention, a method of increasing the rate of growth of an immature
animal is disclosed. The method comprises feeding to the animal a
food supplement according to the present invention prior or during
a growth phase in the animal. Growth rate may be increased by 1% to
200% for a given growth phase when compared to normal or the
increase may be in the overall growth of the animal over time when
compared to normal.
[0054] In an additional example embodiment of the present
invention, a method of optimizing a feeding regime is disclosed.
The method comprises monitoring the bacterial content in the gut or
the growth rate of an animal being fed the food supplement
according to the present invention and adjusting the amount of food
supplement according to the present invention being fed to an
animal based on the bacterial content in the gut or the growth rate
of the animal. Growth rate can be measured using standard
techniques. Such techniques include, but are not limited to, body
mass, body mass index, height, or displacement. Bacterial content
in the gut can be monitored as detailed supra. The amount of food
supplement in the diet of the animal can be adjusted in reference
to growth rate or bacterial content in the gut to achieve the
highest growth rate or an optimal bacterial content.
[0055] Surprisingly, the food supplement of the present invention
was also discovered to eradicate rodent pests. Rodents that consume
the food supplement of the invention die, presumably because the
hygroscopic swelling of the psyllium husks blocks or bursts the
rodent's gastrointestinal tract. This unexpected benefit of the
present invention is particularly advantageous because the same
material can be used concurrently to treat gastrointestinal
problems in economically significant animals and to eradicate
rodent pests.
[0056] Although the present invention has been described with
respect to the currently preferred embodiments set forth herein,
various additions, deletions and modifications are contemplated as
being within its scope. The scope of the invention is, therefore,
indicated by the ensuing claims, rather than the foregoing
description. All changes that come within the meaning and range of
equivalency of the claims are to be embraced within their
scope.
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