U.S. patent application number 11/293697 was filed with the patent office on 2006-05-18 for novel full-length cdna.
This patent application is currently assigned to RESEARCH ASSOCIATION FOR BIOTECHNOLOGY. Invention is credited to Yuri Hio, Ryotaro Irie, Shizuko Ishii, Takao Isogai, Yuuko Isono, Yasuhiko Masuho, Kenji Nagahari, Keiichi Nagai, Kaoru Otsuka, Motoyuki Otsuka, Tetsuji Otsuki, Hiroyuki Sato, Naohiko Seki, Tomoyasu Sugiyama, Ichiro Tamechika, Ai Wakamatsu, Jun-ichi Yamamoto, Tsutomu Yoshikawa.
Application Number | 20060105376 11/293697 |
Document ID | / |
Family ID | 27785577 |
Filed Date | 2006-05-18 |
United States Patent
Application |
20060105376 |
Kind Code |
A1 |
Isogai; Takao ; et
al. |
May 18, 2006 |
Novel full-length cDNA
Abstract
Novel full-length cDNAs are provided. 2443 cDNA derived from
human have been isolated. The full-length nucleotide sequences of
the cDNA and amino acid sequences encoded by the nucleotide
sequences have been determined. Because the cDNA of the present
invention are full-length and contain the translation start site,
they provide information useful for analyzing the functions of the
polypeptide.
Inventors: |
Isogai; Takao; (Ibaraki,
JP) ; Sugiyama; Tomoyasu; (Tokyo, JP) ;
Otsuki; Tetsuji; (Chiba, JP) ; Wakamatsu; Ai;
(Chiba, JP) ; Sato; Hiroyuki; (Osaka, JP) ;
Ishii; Shizuko; (Chiba, JP) ; Yamamoto; Jun-ichi;
(Chiba, JP) ; Isono; Yuuko; (Chiba, JP) ;
Hio; Yuri; (Chiba, JP) ; Otsuka; Kaoru;
(Saitama, JP) ; Nagai; Keiichi; (Tokyo, JP)
; Irie; Ryotaro; (Chiba, JP) ; Tamechika;
Ichiro; (Osaka, JP) ; Seki; Naohiko; (Chiba,
JP) ; Yoshikawa; Tsutomu; (Chiba, JP) ;
Otsuka; Motoyuki; (Tokyo, JP) ; Nagahari; Kenji;
(Tokyo, JP) ; Masuho; Yasuhiko; (Tokyo,
JP) |
Correspondence
Address: |
FOLEY AND LARDNER LLP;SUITE 500
3000 K STREET NW
WASHINGTON
DC
20007
US
|
Assignee: |
RESEARCH ASSOCIATION FOR
BIOTECHNOLOGY
|
Family ID: |
27785577 |
Appl. No.: |
11/293697 |
Filed: |
December 5, 2005 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
|
|
10108260 |
Mar 28, 2002 |
|
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11293697 |
Dec 5, 2005 |
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Current U.S.
Class: |
435/6.16 ;
435/320.1; 435/325; 435/69.1; 435/7.1; 530/350; 536/23.5 |
Current CPC
Class: |
G01N 33/566 20130101;
C07K 14/47 20130101; G01N 2500/00 20130101 |
Class at
Publication: |
435/006 ;
435/007.1; 435/069.1; 435/320.1; 435/325; 530/350; 536/023.5 |
International
Class: |
C12Q 1/68 20060101
C12Q001/68; G01N 33/53 20060101 G01N033/53; C07H 21/04 20060101
C07H021/04; C12P 21/06 20060101 C12P021/06 |
Foreign Application Data
Date |
Code |
Application Number |
Mar 22, 2002 |
JP |
2002-137785 |
Claims
1-14. (canceled)
15. A polynucleotide selected from the group consisting of the
following (a) to (g): (a) a polynucleotide comprising a
protein-coding region of the nucleotide sequence of any one of SEQ
ID NOs: 1 to 2443; (b) a polynucleotide encoding a polypeptide
comprising the amino acid sequence of any one of SEQ ID NOs: 2444
to 4886; (c) a polynucleotide comprising a nucleotide sequence
encoding a polypeptide comprising the amino acid sequence of any
one of SEQ ID NOs: 2444 to 4886, wherein, in said amino acid
sequence, one or more amino acids have been substituted, deleted,
inserted, and/or added, and wherein said nucleotide sequence
encodes a polypeptide functionally equivalent to a polypeptide
comprising the selected amino acid sequence; (d) a polynucleotide
hybridizing to a polynucleotide comprising the nucleotide sequence
of any one of SEQ ID NOs: 1 to 2443, wherein said nucleotide
sequence encodes a polypeptide functionally equivalent to a
polypeptide encoded by the selected nucleotide sequence; (e) a
polynucleotide comprising a nucleotide sequence encoding a partial
amino acid sequence of a polypeptide encoded by the polynucleotide
according to any one or (a) to (d); (f) a polynucleotide comprising
a nucleotide sequence having at least 70% identity to the
nucleotide sequence of any one of SEQ ID Nos: 1 to 2443; and (g) a
polynucleotide comprising sequences having at least 90% identity to
the nucleotide sequence of any one of SEQ ID NOs: 1 to 2443.
16. A polypeptide encoded by the polynucleotide of claim 15, or a
partial peptide thereof.
17. An antibody binding to the polypeptide or the peptide of claim
16.
18. A method for immunologically assaying the polypeptide or the
peptide of claim 16, said method comprising the steps of contacting
the polypeptide or the peptide with the antibody binding to said
polypeptide or said peptide, and observing the binding between the
two.
19. A vector comprising the polynucleotide of claim 15.
20. A transformant carrying the polynucleotide of claim 15 or a
vector comprising said polynucleotide.
21. A transformant carrying the polynucleotide of claim 15 or a
vector comprising said polynucleotide in an expressible manner.
22. A method for producing a polypeptide or a peptide, said method
comprising the steps of culturing the transformant of claim 21 and
recovering an expression product.
23. An oligonucleotide comprising at least 15 nucleotides, said
oligonucleotide comprising a nucleotide sequence complementary to
the nucleotide sequence of any one of SEQ ID NOs: 1 to 2443 or to a
complementary strand thereof.
24. A method for synthesizing the polynucleotide of claim 15, said
method utilizing an oligonucleotide, which comprises a nucleotide
sequence complementary to the nucleotide sequence of any one of SEQ
ID NOs 1 to 2443 or to a complementary strand thereof, and
comprises at least 15 nucleotides.
25. A method for detecting the polynucleotide of claim 15, said
method utilizing an oligonucleotide, which comprises a nucleotide
sequence complementary to the nucleotide sequence of any one of SEQ
ID NOs: 1 to 2443 or to a complementary strand thereof, and
comprises at least 15 nucleotides.
26. An antisense polynucleotide against the polynucleotide of claim
15 or a part thereof.
27. A method for detecting the polynucleotide of claim 15, said
method comprising the following steps of: (a) incubating a target
polynucleotide with an oligonucleotice under hybridizable
conditions, wherein said oligonucleotide comprises a nucleotide
sequence complementary to the nucleotide sequence of any one of SEQ
ID NOs: 1 to 2443 or to a complementary strand thereof, and
comprises at least 15 nucleotides, and (b) detecting hybridization
of the target polynucleotide with the oligonucleotide.
28. A database of polynucleotides and/or polypeptides, said
database comprising information on at least one of the nucleotide
sequences of SEQ ID NOs: 1 to 2443 and/or on at least one of the
amino acid sequences of SEQ ID NOs: 2444 to 4886.
Description
FIELD OF THE INVENTION
[0001] The present invention relates to polynucleotides encoding
novel polypeptides, polypeptides encoded by the polynucleotides,
and new uses of these.
BACKGROUND OF THE INVENTION
[0002] Currently, the sequencing projects, the determination and
analysis of the genomic DNA of various living organisms have been
in progress all over the world. The whole genomic sequences of more
than 40 species of prokaryotes, a lower eukaryote, yeast, a
multicellular eukaryote, C. elegans, and a higher plants,
arabidopsis, etc. are already determined. For human genome,
presumably having 3 billion base pairs, the analysis was advanced
under global cooperative organization, and a draft sequence was
disclosed in 2001. Moreover, all the structures are to be clear and
to be disclosed in 2002-2003. The aim of the determination of
genomic sequence is to reveal the functions of all genes and their
regulation and to understand living organisms as a network of
interactions between genes, proteins, cells or individuals through
deducing the information in a genome, which is a blueprint of the
highly complicated living organisms. To understand living organisms
by utilizing the genomic information from various species is not
only important as an academic subject, but also socially
significant from the viewpoint of industrial application.
[0003] However, determination of genomic sequences itself cannot
identify the functions of all genes. For example, as for yeast,
only the function of approximately half of the 6000 genes, which is
predicted based on the genomic sequence, was able to be deduced. On
the other hand, the human genome has been estimated to contain
about 30,000-40,000 genes. Further, 100,000 or more types of mRNAs
are said to exist when variants produced by alternative splicing
are taken into consideration. Therefore, it is desirable to
establish "a high throughput analysis system of the gene functions"
which allows us to identify rapidly and efficiently the functions
of vast amounts of the genes obtained by the genomic
sequencing.
[0004] Many genes in the eukaryotic genome are split by introns
into multiple exons. Thus, it is difficult to predict correctly the
structure of encoded protein solely based on genomic information.
In contrast, cDNA, which is produced from mRNA that lacks introns,
encodes a protein as a single continuous amino acid sequence and
allows us to identify the primary structure of the protein easily.
In human cDNA research, to date, more than three million ESTs
(Expression Sequence Tags) are publicly available, and the ESTs
presumably cover not less than 80% of all human genes.
[0005] The information of ESTs is utilized for analyzing the
structure of human genome, or for predicting the exon-regions of
genomic sequences or their expression profile. However, many human
ESTs have been derived from proximal regions to the 3'-end of cDNA,
and information around the 5'-end of mRNA is extremely little.
Among human cDNAs, the number of the corresponding mRNAs whose
encoding full-length protein sequences are deduced is approximately
13,000.
[0006] It is possible to identify the transcription start site of
mRNA on the genomic sequence based on the 5'-end sequence of a
full-length cDNA, and to analyze factors involved in the stability
of mRNA that is contained in the cDNA, or in its regulation of
expression at the translation stage. Also, since a full-length cDNA
contains atg codon, the translation start site, in the 5'-region,
it can be translated into a protein in a correct frame. Therefore,
it is possible to produce a large amount of the protein encoded by
the cDNA or to analyze biological activity of the expressed protein
by utilizing an appropriate expression system. Thus, analysis of a
full-length cDNA provides valuable information which complements
the information from genome sequencing. Also, full-length cDNA
clones that can be expressed are extremely valuable in empirical
analysis of gene function and in industrial application.
[0007] Therefore, if a novel human full-length cDNA is isolated, it
can be used for developing medicines for diseases in which the gene
is involved. The protein encoded by the gene can be used as a drug
by itself. Thus, it has great significance to obtain a full-length
cDNA encoding a novel human protein.
[0008] In particular, human secretory proteins or membrane proteins
would be useful by itself as a medicine like tissue plasminogen
activator (TPA), or as a target of medicines like membrane
receptors. In addition, genes for signal transduction-related
proteins (protein kinases, etc.), glycoprotein-related proteins,
transcription-related proteins, etc. are genes whose relationships
to human diseases have been elucidated. Moreover, genes for
disease-related proteins form a gene group rich in genes whose
relationships to human diseases have been elucidated.
[0009] Therefore, it has great significance to isolate novel
full-length cDNA clones of human, only few of which has been
isolated. Especially, isolation of a novel cDNA clone encoding a
secretory protein or membrane protein is desired since the protein
itself would be useful as a medicine, and also the clones
potentially include a gene involved in diseases. In addition, genes
encoding proteins that are involved in signal transduction,
glycoprotein, transcription, or diseases are expected to be useful
as target molecules for therapy, or as medicines themselves. These
genes form a gene group predicted to be strongly involved in
diseases. Thus, identification of the full-length cDNA clones
encoding those proteins has great significance.
SUMMARY OF THE INVENTION
[0010] An objective of the present invention is to provide
polynucleotides encoding novel polypeptides, polypeptides encoded
by the polynucleotides, and novel usages of these.
[0011] The inventors have developed a method for efficiently
cloning, from a cDNA library having very high fullness-ratio, a
human full-length cDNA that is predicted to be a full-length cDNA
clone, where the cDNA library is synthesized by an improved method
(WO 01/04286) of the oligo-capping method (K. Maruyama and S.
Sugano, Gene, 138: 171-174 (1994); Y. Suzuki et al., Gene, 200:
149-156 (1997)). Then, the nucleotide sequences of cDNA clones
whose fullness ratio is high, obtained by this method, were
determined mainly from their 5'-ends, and, if required, from
3'-ends.
[0012] Further, representative clones, which were estimated to be
novel and full-length, among the clones obtained, were analyzed for
their full-length nucleotide sequences. The determined full-length
nucleotide sequences were analyzed by BLAST homology search of the
databases shown below. Because the homology search of the present
invention is carried out based on the information of full-length
cDNAs including the entire coding regions, homology to every part
of a polypeptide can be analyzed. Thus, in the present invention,
the reliability of homology search has been greatly improved.
[1] SwissProt
(http://www.ebi.ac.uk/ebi_docsSwissProt_db/swisshome.html),
[2] GenBank (http://www.ncbi.nlm.nih.gov/web/GenBank),
[3] UniGene (Human) (http://www.ncbi.nlm.nih.gov/UniGene), and
[0013] [4] nr (a protein database, which has been constructed by
combining data of coding sequences (CDS) in nucleotide sequences
deposited in GenBank, and data of SwissProt, PDB
(http://www.rcsb.org/pdb/index.html), PIR
(http://pir.georgetown.edu/pirwww/pirhome.shtml), and PRF
(http://www.prf.or.jp/en/); overlapping sequences have been
removed.)
[0014] Further, the gene expression profiles of cDNA clones whose
full-length nucleotide sequence had been determined were studied by
analyzing the large-scale cDNA database constructed based on the
5'-end nucleotide sequences of cDNAs obtained. In addition to the
analysis for the expression profile by computer, the profiles of
gene expression in living cells were also determined by PCR. The
present inventors revealed the usefulness of the genes of the
present invention based on these analysis results.
[0015] In the present invention, gene functions were revealed by
the analysis of expression profiles in silico based on the
information of full-length nucleotide sequences. The expression
profiles used in the expression frequency analysis were studied
based on the database containing sufficient amount of fragment
sequence data. The expression frequency analysis was carried out by
referring, for these expression profiles, to the full-length
nucleotide sequences of many cDNA clones obtained in the present
invention. Thus, a highly reliable analysis can be achieved by
referring to the full-length nucleotide sequences of a wide variety
of genes for the sufficiently large population for analysis
(expression profiles). Namely, the results of expression frequency
analysis using the full-length sequences of the present invention
more precisely reflect the gene expression frequency in tissues and
cells from which a certain cDNA library was derived. In other
words, the information of full-length cDNA nucleotide sequence of
the present invention made it possible to achieve the highly
reliable expression frequency analysis.
[0016] The full-length cDNA clones of this invention were obtained
by the method comprising the steps of [1] preparing libraries
containing cDNAs with the high fullness ratio by oligo-capping, and
[2] assembling 5'-end sequences and selecting one with the highest
probability of completeness in length in the cluster formed (there
are many clones longer in the 5'-end direction). However, the uses
of primers designed based on the 5'- and 3'-end sequences of
polynucleotides provided by the present invention enable readily
obtaining full-length cDNAs without such a special technique. The
primer, which is designed to be used for obtaining cDNAs capable of
being expressed, is not limited to the 5'- and 3'-end sequences of
polynucleotide.
[0017] Specifically, the present invention relates to a
polynucleotide selected from the group consisting of the following
(a) to (g):
[0018] (a) a polynucleotide comprising a protein-coding region of
the nucleotide sequence of any one of SEQ ID NOs shown in Table
1;
[0019] (b) a polynucleotide encoding a polypeptide comprising the
amino acid sequence of any one of SEQ ID NOs shown in Table 1;
[0020] (c) a polynucleotide comprising a nucleotide sequence
encoding a polypeptide comprising the amino acid sequence of any
one of SEQ ID NOs shown in Table 1, wherein, in said amino acid
sequence, one or more amino acids have been substituted, deleted,
inserted, and/or added, and wherein said nucleotide sequence
encodes a polypeptide functionally equivalent to a polypeptide
comprising the selected amino acid sequence;
[0021] (d) a polynucleotide hybridizing under stringent conditions
to a polynucleotide comprising the nucleotide sequence of any one
of SEQ ID NOs shown in Table 1, wherein said nucleotide sequence
encodes a polypeptide functionally equivalent to a polypeptide
encoded by the selected nucleotide sequence;
[0022] (e) a polynucleotide comprising a' nucleotide sequence
encoding a partial amino acid sequence of a polypeptide encoded by
the polynucleotide according to any one of (a) to (d);
[0023] (f) a polynucleotide comprising a nucleotide sequence having
at least 70% identity to the nucleotide sequence of (a); and
[0024] (g) a polynucleotide comprising a nucleotide sequence having
at least 90% identity to the nucleotide sequence of (a).
[0025] The present invention also relates to a polypeptide encoded
by the above-mentioned polynucleotide or a partial peptide thereof,
an antibody binding to the polypeptide or the peptide, and a method
for immunologically assaying the polypeptide or the peptide, which
comprises the steps of contacting the polypeptide or the peptide
with the antibody, and observing the binding between the two.
[0026] Furthermore, the present invention features a vector
comprising the above-mentioned polynucleotide, a transformant
carrying the polynucleotide or the vector, a transformant carrying
the polynucleotide or the vector in an expressible manner, and a
method for producing the polypeptide or the peptide, which
comprises the steps of culturing the transformant and recovering an
expression product.
[0027] Another feature of the present invention is an
oligonucleotide comprising at least 15 nucleotides, said
oligonucleotide comprising a nucleotide sequence complementary to
the nucleotide sequence of any one of SEQ ID NOs: 1 to 2443 or to a
complementary strand thereof. This oligonucleotide can be used as a
primer for synthesizing the above-mentioned polynucleotide or used
as a probe for detecting the polynucleotide. The present invention
includes an antisense polynucleotide against the polynucleotide or
a part thereof, and a method for detecting the polynucleotide,
which comprises the following steps of:
a) incubating a target polynucleotide with the oligonucleotide
under hybridizable conditions, and
b) detecting hybridization of the target polynucleotide with the
oligonucleotide.
[0028] Still another feature of the present invention is database
of polynucleotides and/or polypeptides, said database comprising
information on at least one of the nucleotide sequences of SEQ ID
NOs: 1 to 2443 and/or on at least one of the amino acid sequences
of SEQ ID NOs: 2444 to 4886.
[0029] Herein, "polynucleotide" is defined as a molecule, such as
DNA and RNA, in which multiple nucleotides are polymerized. There
are no limitations on the number of the polymerized nucleotides. In
case that the polymer contains relatively low number of
nucleotides, it is also described as an "oligonucleotide", which is
included in the "polynucleotide" of the present invention. The
polynucleotide or the oligonucleotide of the present invention can
be a natural or chemically synthesized product. Alternatively, it
can be synthesized using a template polynucleotide by an enzymatic
reaction such as PCR. Furthermore, the polynucleotide of the
present invention may be modified chemically. Moreover, not only a
single-strand polynucleotide but also a double-strand
polynucleotide is included in the present invention. In this
specification, especially in claims, when the polynucleotide is
described merely as "polynucleotide", it means not only a
single-strand polynucleotide but also a double-strand
polynucleotide. When it means double-strand polynucleotide, the
nucleotide sequence of only one chain is indicated. However, based
on the nucleotide sequence of a sense chain, the nucleotide
sequence of the complementary strand thereof is essentially
determined.
[0030] As used herein, an "isolated polynucleotide" is a
polynucleotide the structure of which is not identical to that of
any naturally occurring polynucleotide or to that of any fragment
of a naturally occurring genomic polynucleotide spanning more than
three separate genes. The term therefore includes, for example, (a)
a DNA which has the sequence of part of a naturally occurring
genomic DNA molecule in the genome of the organism in which it
naturally occurs; (b) a polynucleotide incorporated into a vector
or into the genomic DNA of a prokaryote or eukaryote in a manner
such that the resulting molecule is not identical to any naturally
occurring vector or genomic DNA; (c) a separate molecule such as a
cDNA, a genomic fragment, a fragment produced by polymerase chain
reaction (PCR), or a restriction fragment; and (d) a recombinant
nucleotide sequence that is part of a hybrid gene, i.e., a gene
encoding a fusion polypeptide. Specifically excluded from this
definition are polynucleotides of DNA molecules present in mixtures
of different (i) DNA molecules, (ii) transfected cells, or (iii)
cell clones; e.g., as these occur in a DNA library such as a cDNA
or genomic DNA library.
[0031] The term "substantially pure" as used herein in reference to
a given protein or polypeptide means that the protein or
polypeptide is substantially free from other biological
macromolecules. For example, the substantially pure protein or
polypeptide is at least 75%, 80%, 85%, 95%, or 99% pure by dry
weight. Purity can be measured by any appropriate standard method
known in the art, for example, by column chromatography,
polyacrylamide gel electrophoresis, or HPLC analysis.
[0032] All the cDNAs provided by the present invention are
full-length cDNAs. The "full-length cDNA" herein means that the
cDNA contains the ATG codon, which is the start point of
translation therein. The untranslated regions upstream and
downstream of the protein-coding region, both of which are
naturally contained in natural mRNAs, are not indispensable. It is
preferable that the full-length cDNAs of the present invention
contain the stop codon.
BRIEF DESCRIPTION OF THE DRAWINGS
[0033] FIG. 1 shows the restriction map of the vector
pME18SFL3.
DETAILED DESCRIPTION OF THE INVENTION
[0034] All the clones (2443 clones) of the present invention are
novel and encode the full-length polypeptides. Further, all the
clones are cDNAs with the high fullness ratio, which were obtained
by oligo-capping method, and also clones which are not identical to
any of known human mRNAs (namely, novel clones) selected by
searching, for the 5'-end sequences, mRNA sequences with the
annotation of "complete cds" in the GenBank and UniGene databases
by using the BLAST homology search [S. F. Altschul, W. Gish, W.
Miller, E. W. Myers & D. J. Lipman, J. Mol. Biol., 215: 403-410
(1990); W. Gish & D. J. States, Nature Genet., 3: 266-272
(1993)]; they are also clones that were assumed to have higher
fullness ratio among the members in the cluster formed by
assembling. Most of the clones assessed to have high fullness ratio
in the cluster had the nucleotide sequences longer in the 5'-end
direction.
[0035] All the full-length cDNAs of the present invention can be
synthesized by a method such as PCR (Current protocols in Molecular
Biology edit. Ausubel et al. (1987) Publish. John Wiley & Sons
Section 6.1-6.4) using primer sets designed based on the 5'-end and
3'-end sequences or using primer sets of primers designed based on
the 5'-end sequences and a primer of oligo dT sequence
corresponding to poly A sequence. Table 1 contains the clone names
of full-length cDNA of 2443 clones of the present invention, SEQ ID
NOs of the full-length nucleotide sequences, CDS portions deduced
from the full-length nucleotide sequences, and SEQ ID NOs of the
translated amino acids. The positions of CDS are shown according to
the rule of "DDBJ/EMBL/GenBank Feature Table Definition"
(http://www.ncbi.nlm.nih.gov/collab/FT/index.html). The start
position number corresponds to the first letter of "ATG" that is
the nucleotide triplet encoding methionine; the termination
position number corresponds to the third letter of the stop codon.
These are indicated being flanked with the mark "..". However, with
respect to the clones having no stop codon, the termination
position is indicated by the mark ">" according to the above
rule. TABLE-US-00001 TABLE 1 SEQ ID NO. SEQ ID NO. Clone of
nucleotide Position of amino acid name sequence of CDS sequence
3NB6910001910 1 30..1661 2444 3NB6920014080 2 80..922 2445
3NB6920014590 3 1..693 2446 ADIPS10000640 4 127..1098 2447
ADIPS20004250 5 170..2212 2448 ADRGL10001470 6 368..829 2449
ADRGL20000640 7 599..1345 2450 ADRGL20011190 8 61..>2254 2451
ADRGL20012870 9 827..1300 2452 ADRGL20013010 10 1127..1444 2453
ADRGL20013520 11 226..837 2454 ADRGL20018300 12 320..2233 2455
ADRGL20018540 13 55..363 2456 ADRGL20028570 14 218..976 2457
ADRGL20035850 15 55..522 2458 ADRGL20044590 16 692..1042 2459
ADRGL20048330 17 189..2204 2460 ADRGL20061930 18 293..>1899 2461
ADRGL20067670 19 108..512 2462 ADRGL20068170 20 217..615 2463
ADRGL20068460 21 576..1280 2464 ADRGL20073570 22 556..891 2465
ADRGL20076360 23 159..515 2466 ADRGL20078100 24 418..1563 2467
ADRGL20083310 25 871..1368 2468 ASTRO10001650 26 369..2168 2469
ASTRO20001410 27 319..744 2470 ASTRO20005330 28 196..642 2471
ASTRO20008010 29 735..1169 2472 ASTRO20012490 30 286..783 2473
ASTRO20027430 31 129..848 2474 ASTRO20032120 32 860..1189 2475
ASTRO20033160 33 139..1014 2476 ASTRO20055750 34 16..2007 2477
ASTRO20058630 35 28..957 2478 ASTRO20064750 36 1381..>2654 2479
ASTRO20072210 37 274..>1868 2480 ASTRO20084250 38 35..1381 2481
ASTRO20100720 39 394..714 2482 ASTRO20105820 40 205..1368 2483
ASTRO20106150 41 138..1811 2484 ASTRO20108190 42 791..2539 2485
ASTRO20111490 43 517..921 2486 ASTRO20114370 44 145..1782 2487
ASTRO20114610 45 53..433 2488 ASTRO20125520 46 1674..2456 2489
ASTRO20130500 47 15..2417 2490 ASTRO20136710 48 319..657 2491
ASTRO20138020 49 285..995 2492 ASTRO20141350 50 394..1767 2493
ASTRO20143630 51 103..1305 2494 ASTRO20145760 52 347..2008 2495
ASTRO20152140 53 760..1233 2496 ASTRO20155290 54 208..2298 2497
ASTRO20166810 55 7..381 2498 ASTRO20168470 56 334..1329 2499
ASTRO20173480 57 119..724 2500 ASTRO20181690 58 84..1967 2501
ASTRO20190390 59 2282..2662 2502 BEAST20004540 60 1022..1513 2503
BGGI110000240 61 123..1649 2504 BGGI110001930 62 81..1307 2505
BGGI120006160 63 6..680 2506 BLADE20003400 64 17..1876 2507
BLADE20003890 65 555..2405 2508 BLADE20004630 66 58..405 2509
BNGH420088500 67 2..1270 2510 BRACE20003070 68 310..1563 2511
BRACE20006400 69 32..364 2512 BRACE20011070 70 21..1553 2513
BRACE20019540 71 538..993 2514 BRACE20027620 72 24..1289 2515
BRACE20037660 73 143..469 2516 BRACE20038000 74 646..2187 2517
BRACE20038470 75 963..1307 2518 BRACE20038480 76 1838..2626 2519
BRACE20038850 77 1099..1413 2520 BRACE20039040 78 1273..1671 2521
BRACE20039440 79 216..797 2522 BRACE20039540 80 1153..1905 2523
BRACE20050900 81 115..1788 2524 BRACE20051380 82 1433..1783 2525
BRACE20051690 83 380..742 2526 BRACE20052160 84 20..1024 2527
BRACE20053280 85 736..1524 2528 BRACE20053480 86 24..875 2529
BRACE20053630 87 81..950 2530 BRACE20054500 88 364..669 2531
BRACE20055180 89 156..656 2532 BRACE20056810 90 338..940 2533
BRACE20057190 91 1016..1660 2534 BRACE20057420 92 539..856 2535
BRACE20057620 93 1226..1588 2536 BRACE20057730 94 819..1592 2537
BRACE20058580 95 146..1330 2538 BRACE20058810 96 40..345 2539
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725..1165 2995 BRSSN20097020 553 1352..2092 2996 BRSSN20101100 554
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641..988 3019 BRTHA20004740 577 192..1082 3020 BRTHA20046290 578
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446..835 3023 CD34C30001250 581 59..>3188 3024 CD34C30003140 582
458..2803 3025 CD34C30004240 583 430..1290 3026 CD34C30004940 584
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90..1118 3031 CTONG10000220 589 191..847 3032 CTONG10000620 590
94..2943 3033 CTONG10000930 591 18..2621 3034 CTONG10000940 592
182..868 3035 CTONG10001650 593 1916..2512 3036 CTONG10002770 594
182..>3049 3037 CTONG20002180 595 90..554 3038 CTONG20004690 596
301..885 3039 CTONG20009770 597 321..3287 3040 CTONG20014280 598
176..1723 3041 CTONG20027090 599 280..2370 3042 CTONG20028410 600
600..2936 3043 CTONG20038890 601 961..1371 3044 CTONG20049410 602
157..669 3045 CTONG20050280 603 157..1944 3046 CTONG20052650 604
1210..1647 3047 CTONG20052900 605 130..1548 3048 CTONG20075860 606
63..1391 3049 CTONG20076130 607 11..994 3050 CTONG20077790 608
270..635 3051 CTONG20082690 609 75..896 3052 CTONG20085950 610
905..2125 3053 CTONG20091080 611 166..717 3054 CTONG20091320 612
1223..1627 3055 CTONG20092570 613 690..1601 3056 CTONG20092580 614
1555..1920 3057 CTONG20092680 615 365..823 3058 CTONG20092700 616
224..928 3059 CTONG20093950 617 205..2388 3060 CTONG20095270 618
1147..1611 3061 CTONG20095290 619 312..749 3062 CTONG20095340 620
109..2631 3063 CTONG20096430 621 311..1384 3064 CTONG20096750 622
738..1184 3065 CTONG20097660 623 133..876 3066 CTONG20098440 624
206..1132 3067 CTONG20099380 625 1417..1806 3068 CTONG20099550 626
74..1939 3069 CTONG20099630 627 99..2060 3070 CTONG20100240 628
620..2155 3071 CTONG20101480 629 13..411 3072 CTONG20103480 630
30..356 3073 CTONG20105080 631 28..1260 3074 CTONG20105660 632
75..674 3075 CTONG20106230 633 2015..>3067 3076 CTONG20106520
634 1693..3147 3077 CTONG20108210 635 234..1319 3078 CTONG20114290
636 388..3225 3079 CTONG20114740 637 1191..1832 3080 CTONG20118150
638 144..2831 3081 CTONG20118250 639 52..840 3082 CTONG20119200 640
2128..2637 3083 CTONG20120770 641 2946..3341 3084 CTONG20121010 642
143..1732 3085 CTONG20121580 643 97..>2930 3086 CTONG20124010
644 206..1369 3087 CTONG20124220 645 177..2477 3088 CTONG20124470
646 701..1237 3089 CTONG20124730 647 894..1280 3090 CTONG20125540
648 616..1071 3091 CTONG20125640 649 756..1688 3092 CTONG20126070
650 42..2843 3093 CTONG20127450 651 2271..2624 3094 CTONG20128430
652 330..2180 3095 CTONG20128470 653 916..1479 3096 CTONG20129960
654 118..3249 3097 CTONG20131490 655 1191..1553 3098 CTONG20131560
656 242..>2879 3099 CTONG20132220 657 1155..1598 3100
CTONG20133390 658 679..2304 3101 CTONG20133480 659 86..391 3102
CTONG20133520 660 128..2140 3103 CTONG20136300 661 1078..1521 3104
CTONG20138030 662 3061..3396 3105 CTONG20139070 663 2508..2819 3106
CTONG20139340 664 1182..1535 3107 CTONG20139860 665 28..2169 3108
CTONG20140320 666 2454..2786 3109 CTONG20140580 667 74..1180 3110
CTONG20141650 668 190..570 3111 CTONG20143690 669 169..2583 3112
CTONG20146300 670 1195..1674 3113 CTONG20146970 671 1201..1536 3114
CTONG20147050 672 1304..1648 3115 CTONG20149460 673 149..1942 3116
CTONG20149950 674 42..371 3117 CTONG20150910 675 792..1130 3118
CTONG20153300 676 755..2338 3119 CTONG20153580 677 488..1858 3120
CTONG20155180 678 486..>3005 3121 CTONG20155400 679 1940..2458
3122 CTONG20156780 680 33..3104 3123 CTONG20158040 681 152..1297
3124 CTONG20158150 682 66..2057 3125 CTONG20158660 683 171..2258
3126 CTONG20159530 684 231..1094 3127 CTONG20160560 685
79..>2796 3128 CTONG20161850 686 27..734 3129 CTONG20162170 687
156..734 3130 CTONG20163550 688 772..1134 3131 CTONG20164990 689
1343..1753 3132 CTONG20165050 690 1575..2018 3133 CTONG20186320 691
78..1595 3134 CTONG20200310 692 2..2254 3135 CTONG20265130 693
419..892 3136 CTONG20267700 694 2046..2432 3137 CTONG20273610 695
513..923 3138 D3OST10001090 696 50..1462 3139 D3OST10002670 697
77..853 3140 D3OST10002700 698 84..461 3141 D3OST20006180 699
148..2259 3142 D3OST20006540 700 140..442 3143 D3OST20007340 701
369..1220 3144 D3OST20013280 702 756..1118 3145 D3OST20024170 703
1373..1714 3146 D3OST20024360 704 1984..2361 3147 D3OST20024520 705
3..422 3148 D3OST20036070 706 122..1039 3149 D3OST20037970 707
256..735 3150 D3OST20038560 708 1976..2350 3151 D3OST30002580 709
1509..2957 3152 D3OST30002910 710 1811..2248 3153 D6OST20003580 711
1760..2167 3154 D6OST20004450 712 1513..2547 3155 D6OST20005070 713
2835..3398 3156 D9OST20000310 714 239..637 3157 D9OST20002780 715
644..1360 3158 D9OST20015470 716 187..1386 3159 D9OST20023970 717
872..1327 3160 D9OST20026730 718 145..3159 3161 D9OST20031370 719
616..1251 3162 D9OST20033970 720 24..1181 3163 D9OST20035800 721
524..1057 3164 D9OST20035940 722 217..867 3165 D9OST20040180 723
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471..899 3168 DFNES20001530 726 26..382 3169 DFNES20010910 727
159..1136 3170
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FCBBF10002800 746 485..2818 3189 FCBBF10003220 747 479..832 3190
FCBBF10003670 748 139..1266 3191 FCBBF10003740 749 407..2365 3192
FCBBF10003760 750 1044..1358 3193 FCBBF10003770 751 242..>3001
3194 FCBBF10004120 752 142..816 3195 FCBBF10004370 753 432..1511
3196 FCBBF10005060 754 1340..2323 3197 FCBBF10005460 755 179..2092
3198 FCBBF10005500 756 1518..2123 3199 FCBBF10005740 757 954..1667
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FCBBF20035280 762 13..393 3205 FCBBF20042170 763 186..1337 3206
FCBBF20042560 764 115..576 3207 FCBBF20049300 765 32..631 3208
FCBBF20051220 766 523..948 3209 FCBBF20054280 767 119..535 3210
FCBBF20056370 768 57..704 3211 FCBBF20059090 769 928..1245 3212
FCBBF20064520 770 368..1243 3213 FCBBF20067810 771 68..1231 3214
FCBBF20068820 772 74..712 3215 FCBBF20071860 773 384..911 3216
FCBBF20072650 774 1471..1944 3217 FCBBF20075560 775 730..1086 3218
FCBBF20076330 776 684..998 3219 FCBBF30001840 777 1503..1832 3220
FCBBF30007680 778 9..2117 3221 FCBBF30008470 779 1157..1504 3222
FCBBF30010810 780 149..1483 3223 FCBBF30012350 781 419..1507 3224
FCBBF30012810 782 372..>2409 3225 FCBBF30013770 783 375..2795
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990..1877 3228 FCBBF30016570 786 574..999 3229 FCBBF30018550 787
231..>3402 3230 FCBBF30019120 788 54..398 3231 FCBBF30024750 789
126..560 3232 FCBBF30025560 790 171..1301 3233 FCBBF30028180 791
258..830 3234 FCBBF30033050 792 7..1089 3235 FCBBF30039020 793
955..2727 3236 FCBBF30049550 794 222..>4213 3237 FCBBF30052180
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FCBBF30078290 801 280..1875 3244 FCBBF30083620 802 125..1159 3245
FCBBF30083820 803 298..774 3246 FCBBF30086440 804 192..863 3247
FCBBF30090690 805 545..1657 3248 FCBBF30095260 806 204..686 3249
FCBBF30123470 807 1084..1614 3250 FCBBF30129630 808 257..973 3251
FCBBF30170590 809 1313..1672 3252 FCBBF30172550 810 1350..1703 3253
FCBBF30175310 811 120..1280 3254 FCBBF30178730 812 348..833 3255
FCBBF30189490 813 1935..2468 3256 FCBBF30190850 814 43..1560 3257
FCBBF30195640 815 577..>2751 3258 FCBBF30199610 816 972..1391
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3261 FCBBF30233680 819 28..>4395 3262 FCBBF30238870 820
587..2761 3263 FCBBF30240020 821 248..1747 3264 FCBBF30240960 822
465..1520 3265 FCBBF30242250 823 271..>2723 3266 FCBBF30243640
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FCBBF30262510 834 36..2327 3277 FCBBF30266780 835 2080..2382 3278
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FCBBF30279030 838 1653..2447 3281 FCBBF30281880 839 83..2221 3282
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FEBRA20007620 850 61..2400 3293 FEBRA20009090 851 667..1032 3294
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FEBRA20018280 854 16..678 3297 FEBRA20018690 855 664..981 3298
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3302 FEBRA20026280 860 54..623 3303 FEBRA20027810 861 155..2740
3304 FEBRA20029860 862 29..757 3305 FEBRA20034360 863 1288..2013
3306 FEBRA20034680 864 240..1955 3307 FEBRA20037260 865 2376..2702
3308 FEBRA20037500 866 10..1308 3309 FEBRA20040530 867 76..1407
3310 FEBRA20042190 868 1590..1925 3311 FEBRA20052910 869 1136..1486
3312 FEBRA20060610 870 599..1201 3313 FEBRA20072120 871 106..2877
3314 FEBRA20079310 872 2384..2806 3315 FEBRA20080810 873 679..1401
3316 FEBRA20082010 874 106..1779 3317 FEBRA20082100 875 1042..1524
3318 FEBRA20086620 876 215..1591 3319 FEBRA20088360 877 2964..3521
3320 FEBRA20090290 878 383..823 3321 FEBRA20092890 879 198..2297
3322 FEBRA20093520 880 651..1070 3323 FEBRA20095140 881
264..>2245 3324 FEBRA20095880 882 1872..2186 3325 FEBRA20097310
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859..1221 3328 FEBRA20113560 886 22..558 3329 FEBRA20125070 887
10..1002 3330 FEBRA20130190 888 131..1192 3331 FEBRA20132740 889
770..1111 3332 FEBRA20140100 890 1664..2377 3333 FEBRA20144170 891
342..1976 3334 FEBRA20145780 892 1262..1564 3335 FEBRA20161120 893
173..484 3336 FEBRA20166540 894 101..511 3337 FEBRA20167390 895
429..869 3338 FEBRA20171380 896 338..2002 3339 FEBRA20174410 897
125..2029 3340 FEBRA20176800 898 1320..1877 3341 FEBRA20184330 899
36..533 3342 FEBRA20192420 900 2120..3799 3343 FEBRA20195820 901
175..678 3344 FEBRA20196370 902 353..2032 3345 FEBRA20196630 903
482..2359 3346 FEBRA20197110 904 632..1222 3347 FEBRA20204000 905
1958..2482 3348 FEBRA20204060 906 366..728 3349 FEBRA20211710 907
282..929 3350 FEBRA20214970 908 620..1264 3351 FEBRA20215500 909
726..1256 3352 FEBRA20216360 910 1398..1904 3353 FEBRA20222040 911
954..1391 3354 FEBRA20223220 912 1254..1898 3355 FEBRA20225040 913
13..1692 3356 FEBRA20226010 914 1439..1933 3357 FEBRA20229560 915
37..381 3358 FEBRA20229630 916 184..987 3359 FEBRA20232850 917
774..1193 3360 FEBRA20233770 918 64..636 3361 FEBRA20235500 919
1206..>2520 3362 FEBRA20237640 920 331..933 3363 FEHRT20003250
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925 210..644 3368 HCHON20001560 926 565..1611 3369 HCHON20002260
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HCHON20003440 929 1982..>2519 3372 HCHON20007380 930 163..1248
3373 HCHON20007510 931 189..2636 3374 HCHON20008150 932
204..>2358 3375 HCHON20008180 933 671..1087 3376 HCHON20008320
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HCHON20009350 936 63..422 3379 HCHON20009560 937 1644..2489 3380
HCHON20010990 938 531..1085 3381 HCHON20011160 939 839..1156 3382
HCHON20014970 940 302..2143 3383 HCHON20015230 941 950..1453 3384
HCHON20015350 942 647..>2887 3385 HCHON20015980 943 100..1413
3386 HCHON20016040 944 3..323 3387 HCHON20016650 945 44..3418 3388
HCHON20022470 946 1526..1978 3389 HCHON20035130 947 1192..1614 3390
HCHON20036420 948 356..811 3391 HCHON20036760 949 228..647 3392
HCHON20040020 950 257..1288 3393 HCHON20043590 951 263..712 3394
HCHON20059870 952 198..2297 3395 HCHON20064590 953 66..2063 3396
HCHON20067220 954 313..642 3397 HCHON20067700 955 160..591 3398
HCHON20068410 956 116..>2811 3399 HCHON20068710 957 335..688
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3402 HCHON20086720 960 133..864 3403 HCHON20097490 961 1434..2819
3404 HCHON20100740 962 138..1277 3405 HEART20003060 963 109..1407
3406 HEART20005410 964 302..784 3407 HEART20017730 965 19..2064
3408 HEART20021840 966 22..507 3409 HEART20025980 967 293..1180
3410 HEART20034320 968 31..2013 3411 HEART20037810 969 803..1108
3412 HEART20049400 970 178..549 3413 HEART20049410 971 44..613 3414
HEART20049800 972 15..509 3415 HEART20061950 973 153..1961 3416
HEART20063340 974 220..1281 3417 HEART20067870 975 256..855 3418
HEART20067890 976 3..338 3419 HEART20072310 977 47..1057 3420
HEART20074430 978 205..540 3421
HEART20077670 979 90..1223 3422 HEART20083640 980 192..1376 3423
HEART20089940 981 150..1523 3424 HEART20090000 982 197..2116 3425
HEART20095990 983 523..1077 3426 HHDPC10000650 984 920..1531 3427
HHDPC10000830 985 110..520 3428 HHDPC20001040 986 2080..2442 3429
HHDPC20006920 987 1758..2066 3430 HHDPC20014320 988 5..526 3431
HHDPC20030490 989 71..529 3432 HHDPC20031130 990 369..2249 3433
HHDPC20034390 991 94..705 3434 HHDPC20034720 992 167..868 3435
HHDPC20057420 993 44..484 3436 HHDPC20057940 994 1..393 3437
HHDPC20064600 995 231..1493 3438 HHDPC20068620 996 515..1816 3439
HHDPC20084140 997 163..2109 3440 HHDPC20091140 998 160..504 3441
HHDPC20091780 999 49..1623 3442 HHDPC20092080 1000 133..702 3443
HHDPC20095280 1001 332..745 3444 HLUNG10000550 1002 729..1058 3445
HLUNG20016330 1003 86..>1958 3446 HLUNG20016770 1004 919..1242
3447 HLUNG20017120 1005 644..1144 3448 HLUNG20023340 1006 228..1181
3449 HLUNG20033780 1007 156..2285 3450 HLUNG20084390 1008 542..997
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3453 KIDNE20003940 1011 187..1986 3454 KIDNE20006780 1012 164..829
3455 KIDNE20007210 1013 27..350 3456 KIDNE20007770 1014 27..1415
3457 KIDNE20008010 1015 127..>1986 3458 KIDNE20009470 1016
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1018 1798..2334 3461 KIDNE20013730 1019 373..777 3462 KIDNE20017130
1020 226..1740 3463 KIDNE20018730 1021 35..631 3464 KIDNE20018970
1022 232..546 3465 KIDNE20020150 1023 215..1645 3466 KIDNE20021680
1024 140..1096 3467 KIDNE20021910 1025 15..2018 3468 KIDNE20021980
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KIDNE20024830 1028 1912..>2715 3471 KIDNE20027250 1029 359..955
3472 KIDNE20027950 1030 97..543 3473 KIDNE20028390 1031 31..519
3474 KIDNE20028720 1032 70..1122 3475 KIDNE20028830 1033 107..1258
3476 KIDNE20029800 1034 1056..1358 3477 KIDNE20067330 1035
930..1865 3478 KIDNE20079440 1036 192..539 3479 KIDNE20096280 1037
266..1354 3480 KIDNE20096470 1038 31..639 3481 KIDNE20100070 1039
471..2204 3482 KIDNE20100840 1040 167..778 3483 KIDNE20101370 1041
9..503 3484 KIDNE20101510 1042 62..1795 3485 KIDNE20102650 1043
322..1614 3486 KIDNE20102710 1044 791..1501 3487 KIDNE20104300 1045
188..>1957 3488 KIDNE20106740 1046 55..411 3489 KIDNE20107390
1047 85..399 3490 KIDNE20107500 1048 180..641 3491 KIDNE20107620
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1051 254..>2578 3494 KIDNE20112000 1052 430..750 3495
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KIDNE20120090 1055 1334..1813 3498 KIDNE20121880 1056 192..866 3499
KIDNE20122910 1057 1623..2006 3500 KIDNE20124400 1058 532..2499
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3507 KIDNE20130450 1065 177..512 3508 KIDNE20131580 1066 194..1912
3509 KIDNE20132180 1067 894..1256 3510 KIDNE20137340 1068 889..1710
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321..653 3521 LIVER10001260 1079 1413..1748 3522 LIVER10004790 1080
112..1113 3523 LIVER20002160 1081 79..1944 3524 LIVER20011130 1082
898..1569 3525 LIVER20011910 1083 27..425 3526 LIVER20028420 1084
1305..1724 3527 LIVER20035110 1085 551..940 3528 LIVER20035680 1086
873..1283 3529 LIVER20038540 1087 6..308 3530 LIVER20045650 1088
2359..2886 3531 LIVER20055200 1089 82..618 3532 LIVER20055440 1090
1611..2240 3533 LIVER20059810 1091 1597..1899 3534 LIVER20062510
1092 631..999 3535 LIVER20064100 1093 279..785 3536 LIVER20064690
1094 172..1161 3537 LIVER20075680 1095 2568..2939 3538
LIVER20080530 1096 44..1426 3539 LIVER20084730 1097 240..788 3540
LIVER20085800 1098 99..416 3541 LIVER20087060 1099 140..2056 3542
LIVER20087510 1100 478..1200 3543 LIVER20091180 1101 18..374 3544
MAMGL10000830 1102 40..1551 3545 MESAN10001260 1103 80..2137 3546
MESAN20004570 1104 354..>2589 3547 MESAN20014500 1105 78..1976
3548 MESAN20025190 1106 1679..2323 3549 MESAN20027090 1107 144..653
3550 MESAN20029400 1108 210..>2998 3551 MESAN20031900 1109
138..2348 3552 MESAN20035290 1110 99..797 3553 MESAN20036460 1111
1203..1844 3554 MESAN20038510 1112 639..1016 3555 MESAN20089360
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1115 143..1201 3558 MESAN20106640 1116 71..712 3559 MESAN20115970
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1119 1396..1875 3562 MESAN20127350 1120 297..1724 3563
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3565 MESAN20136110 1123 188..1582 3566 MESAN20138450 1124 249..647
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3569 MESAN20152770 1127 64..585 3570 MESAN20153910 1128 141..443
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1138 1470..1895 3581 NOVAR10000910 1139 247..1482 3582
NOVAR10001020 1140 136..519 3583 NOVAR20000380 1141 422..844 3584
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NT2NE20010050 1144 1240..1725 3587 NT2NE20010210 1145 231..626 3588
NT2NE20010400 1146 923..1546 3589 NT2NE20010490 1147 105..1499 3590
NT2NE20015240 1148 251..646 3591 NT2NE20021620 1149 785..2266 3592
NT2NE20043780 1150 815..1285 3593 NT2NE20053580 1151 9..413 3594
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NT2NE20074250 1154 9..377 3597 NT2NE20080170 1155 129..2219 3598
NT2NE20089610 1156 1976..2329 3599 NT2NE20089970 1157 150..488 3600
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NT2NE20118960 1160 197..2044 3603 NT2NE20122430 1161 1474..2016
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3606 NT2NE20130190 1164 728..1438 3607 NT2NE20131890 1165
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1177 53..538 3620 NT2NE20177520 1178 636..2108 3621 NT2NE20181650
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NT2NE20184900 1181 2947..>3371 3624 NT2NE20187390 1182 170..580
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3627 NT2RI20005750 1185 66..1088 3628 NT2RI20009870 1186 127..1053
3629 NT2RI20022600 1187 1040..1621 3630 NT2RI20023160 1188 165..947
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3633 NT2RI20025400 1191 315..902 3634 NT2RI20025640 1192 989..1660
3635 NT2RI20028470 1193 140..1297 3636 NT2RI20036670 1194 334..852
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3641 NT2RI20048840 1199 330..1349 3642 NT2RI20050960 1200 223..1701
3643 NT2RI20054050 1201 172..2154 3644 NT2RI20055790 1202 489..1178
3645 NT2RI20056700 1203 115..1491 3646 NT2RI20069730 1204 607..1209
3647 NT2RI20076290 1205 145..1197 3648 NT2RI20086220 1206 67..1068
3649 NT2RI20091730 1207 113..>2585 3650 NT2RI20091940 1208
699..1181 3651 NT2RI20198260 1209 70..372 3652 NT2RI20203900 1210
176..481 3653 NT2RI20207030 1211 33..1181 3654 NT2RI20216250 1212
812..1312 3655 NT2RI20240080 1213 176..1090 3656 NT2RI20244600 1214
195..1010 3657 NT2RI20244960 1215 161..595 3658 NT2RI20250750 1216
263..1186 3659 NT2RI20252550 1217 927..1622 3660 NT2RI20273230 1218
40..1215 3661 NT2RP60000770 1219 1147..2223 3662 NT2RP60000850 1220
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NT2RP70062230 1230 310..2748 3673 NT2RP70063950 1231 499..3750 3674
NT2RP70072690 1232 1108..1545 3675 NT2RP70075240 1233 308..814 3676
NT2RP70077660 1234 2025..2441 3677 NT2RP70078420 1235 622..2025
3678 NT2RP70080850 1236 59..4003 3679 NT2RP70081610 1237 41..730
3680 NT2RP70085440 1238 1856..2317 3681 NT2RP70102350 1239
225..1043 3682 NT2RP70105210 1240 132..1880 3683 NT2RP70110860 1241
803..1129 3684 NT2RP70111320 1242 271..627 3685 NT2RP70122910 1243
789..1112 3686 NT2RP70125160 1244 10..624 3687 NT2RP70130020 1245
372..692 3688 NT2RP70133740 1246 109..972 3689 NT2RP70134990 1247
24..392 3690 NT2RP70137290 1248 10..381 3691 NT2RP70137640 1249
315..>2113 3692 NT2RP70143480 1250 482..1177 3693 NT2RP70147210
1251 258..566 3694 NT2RP70150800 1252 32..445 3695 NT2RP70157890
1253 170..1006 3696 NT2RP70159960 1254 308..967 3697 NT2RP70169110
1255 123..485 3698 NT2RP70175670 1256 89..421 3699 NT2RP70179710
1257 94..2604 3700 NT2RP70181970 1258 59..364 3701 NT2RP70188020
1259 380..796 3702 NT2RP70188710 1260 491..1024 3703 NT2RP70190640
1261 72..1880 3704 NT2RP70192730 1262 180..1253 3705 NT2RP70194450
1263 1074..1901 3706 NT2RP70195430 1264 201..1256 3707
NT2RP70198350 1265 131..832 3708 NT2RP70203790 1266 2156..>2479
3709 NTONG20009770 1267 124..1947 3710 NTONG20013620 1268
1798..2325 3711 NTONG20015870 1269 65..1627 3712 NTONG20028070 1270
9..545 3713 NTONG20029480 1271 318..1898 3714 NTONG20029700 1272
242..1693 3715 NTONG20046140 1273 308..1108 3716 NTONG20048060 1274
1488..1961 3717 NTONG20049910 1275 47..679 3718 NTONG20050620 1276
141..521 3719 NTONG20050860 1277 59..877 3720 NTONG20051530 1278
78..1697 3721 NTONG20052650 1279 84..>2351 3722 NTONG20056570
1280 226..1326 3723 NTONG20061870 1281 100..996 3724 NTONG20063010
1282 219..1856 3725 NTONG20064400 1283 11..1330 3726 NTONG20064840
1284 1500..2447 3727 NTONG20065010 1285 156..494 3728 NTONG20066460
1286 121..1458 3729 NTONG20067090 1287 1046..1513 3730
NTONG20067830 1288 17..1006 3731 NTONG20070200 1289 318..1418 3732
NTONG20070340 1290 284..1228 3733 NTONG20075220 1291 242..>2591
3734 NTONG20076930 1292 26..1534 3735 NTONG20077560 1293 241..567
3736 NTONG20083650 1294 242..1711 3737 NTONG20088620 1295
60..>2536 3738 NTONG20090600 1296 517..1134 3739 NTONG20090680
1297 673..1389 3740 NTONG20092290 1298 307..1539 3741 NTONG20092330
1299 229..2235 3742 OCBBF10000540 1300 858..1916 3743 OCBBF10001750
1301 245..1144 3744 OCBBF10001850 1302 419..2233 3745 OCBBF20005230
1303 56..640 3746 OCBBF20006770 1304 29..2275 3747 OCBBF20013890
1305 1978..2289 3748 OCBBF20019380 1306 69..1364 3749 OCBBF20019830
1307 325..1536 3750 OCBBF20020150 1308 2507..2917 3751
OCBBF20020830 1309 92..2869 3752 OCBBF20022900 1310 88..1779 3753
OCBBF20023570 1311 47..1276 3754 OCBBF20026630 1312 18..455 3755
OCBBF20028050 1313 128..1108 3756 OCBBF20028650 1314 706..2286 3757
OCBBF20029800 1315 334..699 3758 OCBBF20030280 1316 263..898 3759
OCBBF20030910 1317 383..1258 3760 OCBBF20032460 1318 347..805 3761
OCBBF20035930 1319 65..895 3762 OCBBF20037440 1320 413..1024 3763
OCBBF20039250 1321 24..821 3764 OCBBF20041680 1322 967..1278 3765
OCBBF20045330 1323 1407..1886 3766 OCBBF20046120 1324 82..1641 3767
OCBBF20046470 1325 400..1137 3768 OCBBF20046690 1326 156..1730 3769
OCBBF20047570 1327 182..577 3770 OCBBF20048660 1328 292..663 3771
OCBBF20049300 1329 721..2553 3772 OCBBF20049840 1330 246..>2607
3773 OCBBF20050770 1331 724..>2679 3774 OCBBF20051610 1332
41..493 3775 OCBBF20053430 1333 586..2478 3776 OCBBF20053490 1334
736..1068 3777 OCBBF20053730 1335 87..2090 3778 OCBBF20054200 1336
315..869 3779 OCBBF20054760 1337 195..1016 3780 OCBBF20059560 1338
224..>3045 3781 OCBBF20060300 1339 1389..2171 3782 OCBBF20061720
1340 711..1139 3783 OCBBF20062140 1341 444..749 3784 OCBBF20062410
1342 1920..2240 3785 OCBBF20063320 1343 145..519 3786 OCBBF20066390
1344 2159..2713 3787 OCBBF20068490 1345 15..2702 3788 OCBBF20071210
1346 2029..3486 3789 OCBBF20071840 1347 45..1670 3790 OCBBF20071960
1348 1294..1698 3791 OCBBF20072240 1349 335..1432 3792
OCBBF20072320 1350 1749..2087 3793 OCBBF20073540 1351 56..1132 3794
OCBBF20074140 1352 81..>3793 3795 OCBBF20076220 1353 1552..2013
3796 OCBBF20078920 1354 849..1340 3797 OCBBF20079310 1355 240..1349
3798 OCBBF20079460 1356 12..2099 3799 OCBBF20080050 1357 159..2150
3800 OCBBF20080410 1358 122..1672 3801 OCBBF20081380 1359 742..1140
3802 OCBBF20082830 1360 139..1209 3803 OCBBF20084660 1361 74..1621
3804 OCBBF20085200 1362 659..1207 3805 OCBBF20086400 1363 63..797
3806 OCBBF20086910 1364 541..2304 3807 OCBBF20087010 1365 325..633
3808 OCBBF20088140 1366 1575..1916 3809 OCBBF20088220 1367
2505..2915 3810 OCBBF20091150 1368 256..648 3811 OCBBF20094240 1369
82..1122 3812 OCBBF20097720 1370 471..815 3813 OCBBF20100400 1371
407..3043 3814 OCBBF20103130 1372 114..1439 3815 OCBBF20104040 1373
310..612 3816 OCBBF20105570 1374 2404..2874 3817 OCBBF20107090 1375
127..1935 3818 OCBBF20107920 1376 1692..2018 3819 OCBBF20108190
1377 278..1591 3820 OCBBF20108430 1378 832..1851 3821 OCBBF20108580
1379 1152..2354 3822 OCBBF20108630 1380 249..1133 3823
OCBBF20109310 1381 34..2355 3824 OCBBF20111770 1382 291..629 3825
OCBBF20116850 1383 117..2354 3826 OCBBF20118970 1384 361..855 3827
OCBBF20120390 1385 129..2282 3828 OCBBF20121390 1386 524..2254 3829
OCBBF20122620 1387 990..1544 3830 OCBBF20124360 1388 1223..1951
3831 OCBBF20125530 1389 379..2310 3832 OCBBF20126780 1390
1270..1599 3833 OCBBF20127040 1391 177..2327 3834 OCBBF20127140
1392 1018..1530 3835 OCBBF20127550 1393 103..>2362 3836
OCBBF20128120 1394 118..1311 3837 OCBBF20129360 1395 378..>3283
3838 OCBBF20130110 1396 132..452 3839 OCBBF20130910 1397 2527..2892
3840 OCBBF20132850 1398 1172..3331 3841 OCBBF20139260 1399
772..2592 3842 OCBBF20140640 1400 241..894 3843 OCBBF20140890 1401
39..>4369 3844 OCBBF20145760 1402 894..1757 3845 OCBBF20148280
1403 87..1787 3846 OCBBF20148730 1404 50..1855 3847 OCBBF20149280
1405 1385..2035 3848 OCBBF20151150 1406 135..2216 3849
OCBBF20153340 1407 135..>2621 3850 OCBBF20153350 1408 1616..1942
3851 OCBBF20155060 1409 102..3245 3852 OCBBF20164050 1410 50..370
3853 OCBBF20164670 1411 40..1077 3854 OCBBF20170690 1412 159..503
3855 OCBBF20173060 1413 63..383 3856 OCBBF20173250 1414 315..692
3857 OCBBF20173980 1415 262..1857 3858 OCBBF20178150 1416
1245..2231 3859 OCBBF20178880 1417 2740..3207 3860 OCBBF20178990
1418 1328..1819 3861 OCBBF20180120 1419 218..1780 3862
OCBBF20180840 1420 1169..1540 3863 OCBBF20186870 1421 1278..1736
3864 OCBBF20188730 1422 320..766 3865 OCBBF20189560 1423 1512..2165
3866 PANCR10000910 1424 1219..>1943 3867 PEBLM10000240 1425
306..674 3868 PEBLM10000710 1426 1719..1940 3869 PEBLM20013120 1427
26..952 3870 PEBLM20024320 1428 612..1406 3871 PEBLM20024550 1429
1179..1499 3872 PEBLM20040150 1430 1731..2165 3873 PEBLM20042900
1431 226..>2439 3874 PEBLM20044520 1432 922..1974 3875
PEBLM20052820 1433 411..782 3876 PEBLM20060310 1434 1731..>2083
3877 PEBLM20060360 1435 58..330 3878 PEBLM20060490 1436 431..892
3879 PEBLM20071880 1437 497..814 3880 PEBLM20072960 1438 128..1093
3881 PEBLM20074370 1439 60..458 3882 PEBLM20075980 1440 53..1153
3883 PEBLM20078320 1441 5..1672 3884 PEBLM20085760 1442 122..763
3885 PERIC10000250 1443 689..1516 3886 PERIC20002140 1444 151..1239
3887 PERIC20003860 1445 33..359 3888 PERIC20003870 1446 40..2817
3889 PERIC20004220 1447 130..1935 3890 PERIC20004780 1448 132..956
3891 PLACE50000660 1449 329..2527 3892 PLACE60003480 1450 35..877
3893 PLACE60004630 1451 216..533 3894 PLACE60060420 1452 34..246
3895 PLACE60079250 1453 336..>3307 3896 PLACE60086400 1454
279..764 3897 PLACE60119750 1455 28..570 3898 PLACE60121080 1456
769..1182 3899 PLACE60136500 1457 1900..2241 3900 PLACE60136720
1458 78..2519 3901 PLACE60138830 1459 750..1202 3902 PLACE60153220
1460 247..561 3903 PLACE60155130 1461 833..1171 3904 PLACE60161600
1462 77..1099 3905 PLACE60169420 1463 165..1097 3906 PLACE60177140
1464 1321..2190 3907 PLACE60181070 1465 1355..1708 3908
PLACE60187690 1466 1606..1941 3909 PLACE60188340 1467 430..1224
3910 PROST10003220 1468 187..933 3911 PROST10004800 1469 87..419
3912 PROST20005050 1470 673..1164 3913 PROST20005670 1471
1132..>2293 3914 PROST20021010 1472 612..926 3915 PROST20024890
1473 14..514 3916 PROST20029270 1474 1016..1363 3917 PROST20047270
1475 1300..2250 3918 PROST20047390 1476 163..2283 3919
PROST20050670 1477 1622..2074 3920 PROST20052280 1478 326..634 3921
PROST20057930 1479 237..>2116 3922 PROST20059040 1480 1047..1355
3923
PROST20066880 1481 1937..2521 3924 PROST20079500 1482 863..1957
3925 PROST20083600 1483 209..1087 3926 PROST20087700 1484 481..1287
3927 PROST20097950 1485 91..405 3928 PROST20100460 1486 63..1796
3929 PROST20104000 1487 1059..2012 3930 PROST20107820 1488
304..1524 3931 PROST20111050 1489 772..1281 3932 PROST20112970 1490
66..671 3933 PROST20114390 1491 1291..1749 3934 PROST20116600 1492
4..339 3935 PROST20120050 1493 176..589 3936 PROST20120160 1494
283..597 3937 PROST20121900 1495 68..385 3938 PROST20123530 1496
1619..2044 3939 PROST20127400 1497 1156..1524 3940 PROST20127800
1498 942..2120 3941 PROST20130530 1499 416..1588 3942 PROST20132600
1500 1447..2040 3943 PROST20133270 1501 2..529 3944 PROST20144220
1502 1011..1367 3945 PROST20146010 1503 298..1953 3946
PROST20149160 1504 1677..1991 3947 PROST20149250 1505 635..1201
3948 PROST20151240 1506 300..938 3949 PROST20152460 1507 1542..2084
3950 PROST20153320 1508 184..540 3951 PROST20159240 1509 286..612
3952 PROST20161950 1510 90..716 3953 PROST20164440 1511 2570..3004
3954 PROST20166680 1512 53..874 3955 PROST20168290 1513 1757..2143
3956 PROST20169800 1514 168..1763 3957 PROST20170980 1515 28..1245
3958 PROST20171280 1516 306..1493 3959 PROST20175290 1517
1538..2323 3960 PROST20176170 1518 998..2053 3961 PROST20178360
1519 72..566 3962 PROST20185830 1520 1200..2015 3963 PROST20189770
1521 219..2018 3964 PROST20191640 1522 318..1229 3965 PUAEN10000850
1523 121..2040 3966 PUAEN20003740 1524 104..409 3967 PUAEN20011880
1525 28..2028 3968 PUAEN20015260 1526 141..881 3969 PUAEN20015860
1527 71..1846 3970 PUAEN20018820 1528 41..1870 3971 PUAEN20025680
1529 667..1584 3972 PUAEN20027580 1530 36..512 3973 PUAEN20030180
1531 127..978 3974 PUAEN20040670 1532 326..2644 3975 PUAEN20044000
1533 541..957 3976 PUAEN20045110 1534 335..886 3977 PUAEN20045250
1535 335..1054 3978 PUAEN20051100 1536 228..1319 3979 PUAEN20052470
1537 1699..2046 3980 PUAEN20055020 1538 295..2553 3981
PUAEN20078980 1539 6..989 3982 PUAEN20081230 1540 62..469 3983
PUAEN20083140 1541 104..1687 3984 PUAEN20085150 1542 167..502 3985
PUAEN20108240 1543 2..1993 3986 RECTM10001410 1544 426..1631 3987
RECTM20003490 1545 876..1193 3988 RECTM20005100 1546 149..1273 3989
SALGL10001710 1547 271..1722 3990 SKMUS20001980 1548 75..1034 3991
SKMUS20003610 1549 86..910 3992 SKMUS20007010 1550 24..977 3993
SKMUS20007800 1551 708..>1835 3994 SKMUS20011640 1552 16..408
3995 SKMUS20012010 1553 300..1019 3996 SKMUS20016220 1554 80..1267
3997 SKMUS20018230 1555 98..442 3998 SKMUS20018500 1556 273..1172
3999 SKMUS20020840 1557 79..1014 4000 SKMUS20021530 1558 432..2135
4001 SKMUS20024750 1559 201..1208 4002 SKMUS20028210 1560 358..753
4003 SKMUS20028400 1561 18..644 4004 SKMUS20029200 1562 174..1130
4005 SKMUS20031680 1563 171..485 4006 SKMUS20046670 1564 234..617
4007 SKMUS20048970 1565 104..1132 4008 SKMUS20049030 1566 191..1096
4009 SKMUS20077400 1567 170..772 4010 SKMUS20084740 1568
83..>1516 4011 SKNMC20006220 1569 1176..1856 4012 SKNSH20008190
1570 490..2289 4013 SKNSH20020540 1571 2184..2924 4014
SKNSH20028660 1572 192..581 4015 SKNSH20031740 1573 120..563 4016
SKNSH20034660 1574 562..996 4017 SKNSH20051940 1575 1006..1488 4018
SKNSH20062340 1576 85..453 4019 SKNSH20063040 1577 91..768 4020
SKNSH20080430 1578 81..524 4021 SKNSH20087770 1579 107..>1808
4022 SKNSH20089400 1580 34..1092 4023 SKNSH20091970 1581 181..489
4024 SMINT20001760 1582 267..1706 4025 SMINT20005410 1583 138..557
4026 SMINT20008240 1584 1123..1500 4027 SMINT20009840 1585 31..750
4028 SMINT20011140 1586 1254..1664 4029 SMINT20011580 1587 131..811
4030 SMINT20011990 1588 132..512 4031 SMINT20013480 1589 87..686
4032 SMINT20014580 1590 57..410 4033 SMINT20015590 1591 1375..1818
4034 SMINT20022020 1592 133..726 4035 SMINT20023280 1593 890..1345
4036 SMINT20024570 1594 1852..2370 4037 SMINT20026890 1595
541..2790 4038 SMINT20028820 1596 1240..1749 4039 SMINT20029760
1597 236..1282 4040 SMINT20033170 1598 539..931 4041 SMINT20033400
1599 20..778 4042 SMINT20035690 1600 11..1411 4043 SMINT20040860
1601 39..1169 4044 SMINT20042990 1602 397..750 4045 SMINT20047810
1603 109..588 4046 SMINT20049090 1604 99..641 4047 SMINT20050750
1605 101..907 4048 SMINT20051610 1606 56..1513 4049 SMINT20053300
1607 1251..1598 4050 SMINT20053870 1608 85..894 4051 SMINT20056210
1609 356..754 4052 SMINT20058000 1610 200..565 4053 SMINT20060780
1611 18..554 4054 SMINT20065960 1612 859..1314 4055 SMINT20068010
1613 136..1026 4056 SMINT20071400 1614 212..1183 4057 SMINT20073650
1615 59..1549 4058 SMINT20076470 1616 1678..1983 4059 SMINT20080540
1617 1280..1606 4060 SMINT20089170 1618 54..530 4061 SMINT20092330
1619 169..858 4062 SMINT20092720 1620 1640..2293 4063 SMINT20095050
1621 733..1107 4064 SMINT20098320 1622 112..465 4065 SMINT20100680
1623 237..614 4066 SMINT20101440 1624 187..2109 4067 SMINT20102780
1625 26..1642 4068 SMINT20103690 1626 208..960 4069 SMINT20105000
1627 194..514 4070 SMINT20105330 1628 1580..2020 4071 SMINT20106290
1629 501..1802 4072 SMINT20106720 1630 80..1498 4073 SMINT20108530
1631 185..523 4074 SMINT20109970 1632 1444..>1974 4075
SMINT20110330 1633 1398..2222 4076 SMINT20110660 1634 1108..1500
4077 SMINT20112730 1635 80..1564 4078 SMINT20115880 1636 679..1746
4079 SMINT20121220 1637 263..>1798 4080 SMINT20121950 1638
6..443 4081 SMINT20122850 1639 454..777 4082 SMINT20122910 1640
1516..2094 4083 SMINT20127350 1641 622..1449 4084 SMINT20127930
1642 67..1554 4085 SMINT20130320 1643 178..2601 4086 SMINT20131810
1644 583..1257 4087 SMINT20132280 1645 293..655 4088 SMINT20136130
1646 1291..1752 4089 SMINT20138900 1647 87..1439 4090 SMINT20144430
1648 54..647 4091 SMINT20144800 1649 171..1394 4092 SMINT20144890
1650 209..520 4093 SMINT20152940 1651 386..985 4094 SMINT20153260
1652 135..1838 4095 SMINT20153530 1653 1186..1524 4096
SMINT20154540 1654 107..1339 4097 SMINT20155180 1655 20..763 4098
SMINT20157450 1656 669..1118 4099 SMINT20158100 1657 30..587 4100
SMINT20161220 1658 397..1977 4101 SMINT20162860 1659 36..494 4102
SMINT20163960 1660 665..1036 4103 SMINT20164400 1661 125..706 4104
SMINT20164770 1662 529..870 4105 SMINT20168570 1663 1593..2069 4106
SMINT20173190 1664 251..829 4107 SMINT20173240 1665 253..582 4108
SMINT20174360 1666 978..1733 4109 SMINT20177360 1667 172..771 4110
SMINT20178550 1668 51..692 4111 SMINT20179740 1669 78..1865 4112
SMINT20183530 1670 1130..2530 4113 SMINT20190170 1671 80..1567 4114
SMINT20191420 1672 49..1365 4115 SMINT20191530 1673 40..2040 4116
SMINT20192000 1674 49..435 4117 SPLEN10000830 1675 1586..2053 4118
SPLEN20000640 1676 27..755 4119 SPLEN20002220 1677 87..434 4120
SPLEN20003070 1678 684..1046 4121 SPLEN20006070 1679 78..2837 4122
SPLEN20008390 1680 375..2378 4123 SPLEN20008740 1681 66..1547 4124
SPLEN20008820 1682 31..1872 4125 SPLEN20011410 1683 199..2394 4126
SPLEN20013540 1684 978..1310 4127 SPLEN20016260 1685 906..1748 4128
SPLEN20019450 1686 180..680 4129 SPLEN20020070 1687 65..451 4130
SPLEN20021660 1688 130..771 4131 SPLEN20022230 1689 133..1026 4132
SPLEN20023140 1690 1153..1605 4133 SPLEN20026950 1691 855..3383
4134 SPLEN20027440 1692 29..2488 4135 SPLEN20029310 1693 70..585
4136 SPLEN20031600 1694 1658..2083 4137 SPLEN20032040 1695 357..746
4138 SPLEN20032190 1696 441..785 4139 SPLEN20033960 1697 16..1026
4140 SPLEN20039240 1698 1177..1929 4141 SPLEN20040600 1699 60..368
4142 SPLEN20054290 1700 187..2421 4143 SPLEN20076530 1701 254..586
4144 SPLEN20077500 1702 79..1941 4145 SPLEN20079260 1703 535..1506
4146 SPLEN20079510 1704 1880..>2197 4147 SPLEN20084600 1705
13..1878 4148 SPLEN20095410 1706 816..1541 4149 SPLEN20095550 1707
193..>2558 4150 SPLEN20095810 1708 248..670 4151 SPLEN20097330
1709 1448..1849 4152 SPLEN20099700 1710 91..>3025 4153
SPLEN20101190 1711 1864..2250 4154 SPLEN20103950 1712 25..507 4155
SPLEN20106250 1713 295..711 4156 SPLEN20117660 1714 662..1099 4157
SPLEN20118300 1715 332..1486 4158 SPLEN20119810 1716 526..1644 4159
SPLEN20121750 1717 464..1021 4160 SPLEN20126190 1718 274..2688 4161
SPLEN20128000 1719 96..1664 4162 SPLEN20129610 1720 207..557 4163
SPLEN20140800 1721 387..2144 4164 SPLEN20141360 1722 491..799 4165
SPLEN20141990 1723 443..745 4166 SPLEN20142100 1724 301..996 4167
SPLEN20143180 1725 50..448 4168 SPLEN20144520 1726 2002..2463 4169
SPLEN20145720 1727 1205..>1939 4170 SPLEN20146450 1728 362..862
4171 SPLEN20146690 1729 1966..2550 4172 SPLEN20147110 1730
313..2067 4173 SPLEN20147390 1731 169..1479 4174
SPLEN20149110 1732 2..769 4175 SPLEN20149190 1733 26..364 4176
SPLEN20149240 1734 787..2490 4177 SPLEN20150940 1735 79..2385 4178
SPLEN20151210 1736 66..1715 4179 SPLEN20152610 1737 986..1453 4180
SPLEN20152760 1738 284..628 4181 SPLEN20157300 1739 426..728 4182
SPLEN20157880 1740 35..769 4183 SPLEN20158900 1741 1643..2032 4184
SPLEN20158990 1742 843..1172 4185 SPLEN20160450 1743 552..1115 4186
SPLEN20160690 1744 734..1099 4187 SPLEN20160980 1745 124..456 4188
SPLEN20162680 1746 646..2007 4189 SPLEN20163560 1747 86..2173 4190
SPLEN20165310 1748 80..1492 4191 SPLEN20166270 1749 1134..1814 4192
SPLEN20167200 1750 223..570 4193 SPLEN20169220 1751 160..576 4194
SPLEN20169720 1752 72..2492 4195 SPLEN20170310 1753 125..1039 4196
SPLEN20171210 1754 7..837 4197 SPLEN20171470 1755 41..2272 4198
SPLEN20171890 1756 1312..1716 4199 SPLEN20172120 1757 138..500 4200
SPLEN20173510 1758 235..1785 4201 SPLEN20174260 1759 99..428 4202
SPLEN20176200 1760 36..431 4203 SPLEN20179180 1761 173..1201 4204
SPLEN20179810 1762 1374..3224 4205 SPLEN20181810 1763 641..1183
4206 SPLEN20186430 1764 80..979 4207 SPLEN20193110 1765 1744..2118
4208 SPLEN20194050 1766 1351..2331 4209 SPLEN20198110 1767
1260..1562 4210 SPLEN20204170 1768 202..594 4211 SPLEN20211220 1769
601..1500 4212 SPLEN20211570 1770 174..521 4213 SPLEN20211940 1771
241..1155 4214 SPLEN20212730 1772 979..1830 4215 SPLEN20212950 1773
283..2055 4216 SPLEN20213830 1774 137..460 4217 SPLEN20214400 1775
28..387 4218 SPLEN20214580 1776 300..602 4219 SPLEN20222270 1777
241..927 4220 SPLEN20225220 1778 672..1199 4221 SPLEN20242320 1779
136..522 4222 SPLEN20242730 1780 2343..2732 4223 SPLEN20243830 1781
197..556 4224 SPLEN20245300 1782 945..1529 4225 SPLEN20249560 1783
889..1584 4226 SPLEN20250170 1784 457..3012 4227 SPLEN20250390 1785
1327..1788 4228 SPLEN20252190 1786 1413..2609 4229 SPLEN20261440
1787 511..894 4230 SPLEN20264110 1788 1195..1662 4231 SPLEN20267650
1789 39..1331 4232 SPLEN20273950 1790 608..1222 4233 SPLEN20279950
1791 1874..2518 4234 SPLEN20280660 1792 1286..1612 4235
SPLEN20283650 1793 13..621 4236 SPLEN20284240 1794 282..1175 4237
SPLEN20292950 1795 9..2456 4238 SPLEN20293800 1796 73..858 4239
SPLEN20303970 1797 778..1104 4240 SPLEN20304950 1798 7..1011 4241
SPLEN20305620 1799 1356..1853 4242 SPLEN20329240 1800 5..361 4243
STOMA20001830 1801 81..1574 4244 STOMA20005390 1802 59..1567 4245
STOMA20005670 1803 81..1478 4246 STOMA20006400 1804 80..1687 4247
STOMA20006780 1805 41..1975 4248 STOMA20006860 1806 1272..1988 4249
STOMA20008880 1807 112..1485 4250 STOMA20010250 1808 66..419 4251
STOMA20013890 1809 2151..2486 4252 STOMA20026880 1810 548..874 4253
STOMA20032890 1811 1710..2600 4254 STOMA20034770 1812 81..1583 4255
STOMA20036460 1813 311..772 4256 STOMA20046680 1814 768..1154 4257
STOMA20048520 1815 160..663 4258 STOMA20048840 1816 936..1487 4259
STOMA20051200 1817 140..619 4260 STOMA20056640 1818 49..555 4261
STOMA20056670 1819 81..1556 4262 STOMA20057820 1820 60..1226 4263
STOMA20062130 1821 35..427 4264 STOMA20062290 1822 289..693 4265
STOMA20063250 1823 109..438 4266 STOMA20063980 1824 97..480 4267
STOMA20064470 1825 78..1118 4268 STOMA20067800 1826 35..397 4269
STOMA20069040 1827 364..792 4270 STOMA20072690 1828 351..701 4271
STOMA20076800 1829 311..784 4272 STOMA20077450 1830 780..2300 4273
STOMA20080500 1831 59..1735 4274 STOMA20083610 1832 80..1564 4275
STOMA20086140 1833 201..746 4276 STOMA20088380 1834 48..1535 4277
STOMA20092530 1835 80..1501 4278 STOMA20092560 1836 68..439 4279
STOMA20092890 1837 105..1223 4280 SYNOV20001520 1838 25..735 4281
SYNOV20001730 1839 56..1480 4282 SYNOV20002510 1840 79..1629 4283
SYNOV20002790 1841 59..1480 4284 SYNOV20002970 1842 56..1471 4285
SYNOV20003970 1843 357..881 4286 SYNOV20004260 1844 80..1489 4287
SYNOV20007000 1845 55..1485 4288 SYNOV20008240 1846 61..1494 4289
SYNOV20009230 1847 40..1515 4290 SYNOV20010880 1848 61..1479 4291
SYNOV20011110 1849 56..1468 4292 SYNOV20013000 1850 30..1433 4293
SYNOV20013560 1851 79..1494 4294 SYNOV20013900 1852 81..1499 4295
SYNOV20017080 1853 466..1905 4296 SYNOV30001840 1854 146..2443 4297
TBAES20000590 1855 1697..>2237 4298 TBAES20002550 1856 16..1896
4299 TBAES20003150 1857 42..1064 4300 TBAES20003770 1858 117..3437
4301 TCOLN20001390 1859 237..1106 4302 TESOP20000900 1860 110..448
4303 TESOP20003120 1861 42..929 4304 TESOP20004000 1862 295..1125
4305 TESOP20005270 1863 568..921 4306 TESOP20005690 1864 230..574
4307 TESTI10000940 1865 127..1752 4308 TESTI20001000 1866 129..944
4309 TESTI20001170 1867 107..1291 4310 TESTI20001720 1868 204..722
4311 TESTI20002720 1869 92..>2187 4312 TESTI20002780 1870
821..1471 4313 TESTI20004890 1871 140..1231 4314 TESTI20011200 1872
1615..1968 4315 TESTI20017950 1873 62..2023 4316 TESTI20018230 1874
506..1024 4317 TESTI20023510 1875 100..1935 4318 TESTI20029930 1876
597..1847 4319 TESTI20030310 1877 1362..1757 4320 TESTI20030890
1878 1736..2167 4321 TESTI20031270 1879 820..1332 4322
TESTI20031810 1880 235..1926 4323 TESTI20035960 1881 80..1327 4324
TESTI20036380 1882 125..2110 4325 TESTI20037560 1883 16..1986 4326
TESTI20038270 1884 42..347 4327 TESTI20039400 1885 63..1430 4328
TESTI20041690 1886 194..2320 4329 TESTI20044230 1887 76..1308 4330
TESTI20044310 1888 307..1899 4331 TESTI20046750 1889 56..871 4332
TESTI20057750 1890 154..495 4333 TESTI20060400 1891 102..1754 4334
TESTI20061110 1892 102..1574 4335 TESTI20063830 1893 186..1793 4336
TESTI20066670 1894 345..1823 4337 TESTI20066770 1895 867..1937 4338
TESTI20067200 1896 25..1149 4339 TESTI20076850 1897 864..1307 4340
TESTI20082330 1898 12..2249 4341 TESTI20083200 1899 80..967 4342
TESTI20083940 1900 60..1973 4343 TESTI20086210 1901 65..1465 4344
TESTI20087620 1902 116..2191 4345 TESTI20088220 1903 318..2435 4346
TESTI20094020 1904 341..1885 4347 TESTI20094120 1905 402..1184 4348
TESTI20094230 1906 1397..2158 4349 TESTI20094470 1907 428..1540
4350 TESTI20098350 1908 137..1849 4351 TESTI20098530 1909 220..564
4352 TESTI20102800 1910 278..640 4353 TESTI20105720 1911 1542..1901
4354 TESTI20108720 1912 101..1123 4355 TESTI20110280 1913 212..1396
4356 TESTI20112940 1914 579..899 4357 TESTI20114070 1915 1575..1937
4358 TESTI20116650 1916 43..387 4359 TESTI20116830 1917 825..1208
4360 TESTI20121550 1918 191..1900 4361 TESTI20122310 1919 149..826
4362 TESTI20123080 1920 432..767 4363 TESTI20123560 1921
249..>816 4364 TESTI20127760 1922 149..1141 4365 TESTI20128350
1923 178..591 4366 TESTI20129150 1924 241..969 4367 TESTI20129220
1925 366..773 4368 TESTI20130010 1926 866..1420 4369 TESTI20130120
1927 119..748 4370 TESTI20135660 1928 961..1374 4371 TESTI20136100
1929 71..406 4372 TESTI20136710 1930 14..>1826 4373
TESTI20136990 1931 1903..2292 4374 TESTI20137370 1932 37..339 4375
TESTI20137670 1933 181..561 4376 TESTI20143240 1934 486..908 4377
TESTI20143390 1935 52..1068 4378 TESTI20143620 1936 970..1332 4379
TESTI20148000 1937 250..2004 4380 TESTI20152460 1938 222..1499 4381
TESTI20155900 1939 1095..1499 4382 TESTI20156100 1940 31..1200 4383
TESTI20157100 1941 481..1149 4384 TESTI20157520 1942 55..>1880
4385 TESTI20159140 1943 424..>1611 4386 TESTI20161970 1944
138..1658 4387 TESTI20164100 1945 60..470 4388 TESTI20168480 1946
91..1341 4389 TESTI20168630 1947 1219..1608 4390 TESTI20168960 1948
37..570 4391 TESTI20169960 1949 801..1139 4392 TESTI20170350 1950
1106..1429 4393 TESTI20171020 1951 11..>2194 4394 TESTI20178160
1952 1084..1452 4395 TESTI20179320 1953 191..664 4396 TESTI20183370
1954 190..870 4397 TESTI20184620 1955 123..2417 4398 TESTI20185650
1956 75..1904 4399 TESTI20185810 1957 243..587 4400 TESTI20189410
1958 16..>1759 4401 TESTI20192280 1959 10..906 4402
TESTI20192800 1960 193..>2366 4403 TESTI20193360 1961 66..854
4404 TESTI20194300 1962 70..576 4405 TESTI20194810 1963 78..473
4406 TESTI20197940 1964 771..>1987 4407 TESTI20199170 1965
244..558 4408 TESTI20199750 1966 92..1957 4409 TESTI20200260 1967
307..846 4410 TESTI20200710 1968 190..1749 4411 TESTI20202650 1969
55..1299 4412 TESTI20203440 1970 1109..1600 4413 TESTI20204450 1971
417..1916 4414 TESTI20208400 1972 1027..1782 4415 TESTI20208710
1973 70..2046 4416 TESTI20209460 1974 1035..1400 4417 TESTI20209810
1975 872..1405 4418 TESTI20209990 1976 106..549 4419 TESTI20211160
1977 627..1424 4420 TESTI20211220 1978 1561..1944 4421
TESTI20211240 1979 150..>1469 4422 TESTI20213150 1980 380..1303
4423 TESTI20213580 1981 338..697 4424 TESTI20214250 1982 46..933
4425
TESTI20215990 1983 428..2635 4426 TESTI20216370 1984 572..1195 4427
TESTI20220100 1985 539..1264 4428 TESTI20220650 1986 164..481 4429
TESTI20224620 1987 221..532 4430 TESTI20226230 1988 335..>1500
4431 TESTI20226490 1989 1044..1367 4432 TESTI20229600 1990
342..2669 4433 TESTI20230250 1991 1310..1693 4434 TESTI20230850
1992 246..2567 4435 TESTI20231920 1993 949..1392 4436 TESTI20231940
1994 382..975 4437 TESTI20232140 1995 26..1237 4438 TESTI20234140
1996 182..1738 4439 TESTI20234270 1997 334..642 4440 TESTI20234360
1998 23..460 4441 TESTI20237520 1999 172..1734 4442 TESTI20238000
2000 978..1322 4443 TESTI20238610 2001 150..1373 4444 TESTI20239470
2002 132..2294 4445 TESTI20239510 2003 701..1333 4446 TESTI20240090
2004 10..1179 4447 TESTI20241530 2005 594..1985 4448 TESTI20241920
2006 1309..1632 4449 TESTI20242830 2007 42..2306 4450 TESTI20242990
2008 968..1330 4451 TESTI20244190 2009 80..1630 4452 TESTI20244760
2010 1258..1647 4453 TESTI20249990 2011 698..1960 4454
TESTI20254220 2012 81..1376 4455 TESTI20254540 2013 997..1830 4456
TESTI20254860 2014 205..>2004 4457 TESTI20255820 2015 120..1565
4458 TESTI20258460 2016 37..1212 4459 TESTI20262330 2017 928..1521
4460 TESTI20262910 2018 335..1336 4461 TESTI20265250 2019
1751..2095 4462 TESTI20265370 2020 46..378 4463 TESTI20265970 2021
258..1961 4464 TESTI20266740 2022 88..1203 4465 TESTI20269570 2023
643..1047 4466 TESTI20271850 2024 202..504 4467 TESTI20272060 2025
1379..3253 4468 TESTI20272390 2026 123..767 4469 TESTI20272960 2027
982..1932 4470 TESTI20275030 2028 98..583 4471 TESTI20275620 2029
1508..1840 4472 TESTI20277360 2030 298..1704 4473 TESTI20278200
2031 48..698 4474 TESTI20278400 2032 70..>1856 4475
TESTI20280980 2033 619..1071 4476 TESTI20282540 2034 310..1356 4477
TESTI20284880 2035 683..1114 4478 TESTI20285830 2036 494..853 4479
TESTI20288110 2037 234..899 4480 TESTI20288910 2038 51..965 4481
TESTI20289850 2039 198..698 4482 TESTI20291310 2040 106..2034 4483
TESTI20291620 2041 1611..2021 4484 TESTI20291960 2042 809..1921
4485 TESTI20294700 2043 898..1236 4486 TESTI20297850 2044 1..837
4487 TESTI20301360 2045 114..506 4488 TESTI20303220 2046 288..2711
4489 TESTI20303360 2047 767..2050 4490 TESTI20303420 2048 34..768
4491 TESTI20305540 2049 97..2949 4492 TESTI20305560 2050 49..582
4493 TESTI20307540 2051 88..513 4494 TESTI20307700 2052 32..412
4495 TESTI20308600 2053 72..1307 4496 TESTI20309170 2054 722..2233
4497 TESTI20310070 2055 205..2097 4498 TESTI20311290 2056 940..1398
4499 TESTI20314180 2057 1073..1744 4500 TESTI20316870 2058 25..813
4501 TESTI20317600 2059 107..1420 4502 TESTI20318090 2060
1012..1644 4503 TESTI20319190 2061 384..1481 4504 TESTI20320440
2062 200..1861 4505 TESTI20320670 2063 259..1257 4506 TESTI20326810
2064 832..1377 4507 TESTI20327680 2065 135..1730 4508 TESTI20327740
2066 132..518 4509 TESTI20328280 2067 87..2135 4510 TESTI20330310
2068 315..1307 4511 TESTI20332420 2069 682..1461 4512 TESTI20333000
2070 366..1586 4513 TESTI20333950 2071 76..1500 4514 TESTI20334410
2072 167..1630 4515 TESTI20335050 2073 340..1389 4516 TESTI20335200
2074 612..968 4517 TESTI20336410 2075 17..325 4518 TESTI20337100
2076 40..384 4519 TESTI20342430 2077 322..642 4520 TESTI20343070
2078 530..2563 4521 TESTI20343570 2079 900..1568 4522 TESTI20345060
2080 15..1382 4523 TESTI20347180 2081 3..710 4524 TESTI20347300
2082 623..931 4525 TESTI20347740 2083 100..1599 4526 TESTI20347770
2084 37..351 4527 TESTI20351830 2085 919..1773 4528 TESTI20352620
2086 182..907 4529 TESTI20355020 2087 8..1651 4530 TESTI20357750
2088 547..951 4531 TESTI20357930 2089 1148..1498 4532 TESTI20357960
2090 363..725 4533 TESTI20358980 2091 85..1332 4534 TESTI20361140
2092 801..1514 4535 TESTI20366910 2093 5..1396 4536 TESTI20367360
2094 324..629 4537 TESTI20368330 2095 201..1856 4538 TESTI20369130
2096 243..611 4539 TESTI20369220 2097 118..441 4540 TESTI20369650
2098 633..2204 4541 TESTI20369690 2099 306..1208 4542 TESTI20370020
2100 346..1830 4543 TESTI20370550 2101 160..462 4544 TESTI20370810
2102 223..2334 4545 TESTI20371030 2103 209..1180 4546 TESTI20371060
2104 140..1177 4547 TESTI20373820 2105 237..1109 4548 TESTI20375340
2106 387..1559 4549 TESTI20377230 2107 574..1314 4550 TESTI20378190
2108 380..1795 4551 TESTI20378450 2109 489..>2419 4552
TESTI20380650 2110 961..1272 4553 TESTI20381040 2111 339..1394 4554
TESTI20382750 2112 1159..1797 4555 TESTI20383880 2113 419..988 4556
TESTI20385960 2114 684..1637 4557 TESTI20386230 2115 748..1059 4558
TESTI20386440 2116 185..514 4559 TESTI20388580 2117 405..788 4560
TESTI20390260 2118 142..522 4561 TESTI20390410 2119 1604..1969 4562
TESTI20391130 2120 185..2224 4563 TESTI20391210 2121 1259..1801
4564 TESTI20391770 2122 237..1634 4565 TESTI20392090 2123 405..881
4566 TESTI20392250 2124 1057..1941 4567 TESTI20392270 2125
316..1185 4568 TESTI20392760 2126 306..2279 4569 TESTI20393530 2127
194..1198 4570 TESTI20396130 2128 338..682 4571 TESTI20397760 2129
371..1129 4572 TESTI20400940 2130 231..2705 4573 TESTI20401020 2131
583..1281 4574 TESTI20401280 2132 53..379 4575 TESTI20401430 2133
340..651 4576 TESTI20404240 2134 1110..1550 4577 TESTI20406420 2135
186..1340 4578 TESTI20408150 2136 195..752 4579 TESTI20408970 2137
247..1170 4580 TESTI20409440 2138 17..337 4581 TESTI20409890 2139
120..1082 4582 TESTI20413300 2140 66..503 4583 TESTI20415170 2141
45..419 4584 TESTI20415640 2142 1..324 4585 TESTI20416640 2143
1092..1574 4586 TESTI20417300 2144 107..1807 4587 TESTI20419560
2145 5..331 4588 TESTI20420620 2146 334..2139 4589 TESTI20421490
2147 2188..2628 4590 TESTI20422640 2148 974..2149 4591
TESTI20423020 2149 252..>1770 4592 TESTI20424000 2150 339..842
4593 TESTI20424730 2151 928..1263 4594 TESTI20425070 2152
1145..1726 4595 TESTI20427830 2153 42..380 4596 TESTI20428060 2154
230..598 4597 TESTI20429280 2155 925..1551 4598 TESTI20429580 2156
970..1458 4599 TESTI20432750 2157 56..1399 4600 TESTI20432820 2158
18..1232 4601 TESTI20433130 2159 247..549 4602 TESTI20436560 2160
103..1578 4603 TESTI20438570 2161 1252..1719 4604 TESTI20438660
2162 2227..2622 4605 TESTI20441940 2163 613..1596 4606
TESTI20442760 2164 82..>2054 4607 TESTI20443090 2165 201..1019
4608 TESTI20444130 2166 79..417 4609 TESTI20444180 2167 26..547
4610 TESTI20447540 2168 184..516 4611 TESTI20449200 2169 672..1766
4612 TESTI20451710 2170 429..731 4613 TESTI20451990 2171 210..2264
4614 TESTI20455090 2172 489..1268 4615 TESTI20455620 2173 110..1351
4616 TESTI20456110 2174 4..1191 4617 TESTI20458190 2175 235..579
4618 TESTI20463520 2176 998..1402 4619 TESTI20463580 2177 577..2037
4620 TESTI20465350 2178 317..1258 4621 TESTI20465520 2179 535..1026
4622 TESTI20465690 2180 214..1074 4623 TESTI20467210 2181 435..1613
4624 TESTI20467320 2182 951..1922 4625 TESTI20467970 2183 332..1690
4626 TESTI20468630 2184 380..688 4627 TESTI20471410 2185 97..1464
4628 TESTI20471470 2186 31..369 4629 TESTI20471530 2187 2264..2641
4630 TESTI20472120 2188 517..876 4631 TESTI20473420 2189 140..607
4632 TESTI20473830 2190 951..1532 4633 TESTI20477920 2191
1387..1860 4634 TESTI20478010 2192 169..558 4635 TESTI20478180 2193
428..754 4636 TESTI20478850 2194 949..1323 4637 TESTI20479300 2195
663..1205 4638 THYMU10005360 2196 48..899 4639 THYMU10005540 2197
84..1508 4640 THYMU20000570 2198 216..728 4641 THYMU20011950 2199
45..626 4642 THYMU20015210 2200 1003..1314 4643 THYMU20018190 2201
336..758 4644 THYMU20023380 2202 1426..1728 4645 THYMU20027560 2203
63..602 4646 THYMU20029100 2204 215..928 4647 THYMU20032870 2205
1042..1404 4648 THYMU20039810 2206 54..2204 4649 THYMU20045120 2207
66..425 4650 THYMU20058070 2208 984..1388 4651 THYMU20061700 2209
40..435 4652 THYMU20066100 2210 188..814 4653 THYMU20070360 2211
1333..1635 4654 THYMU20075320 2212 1186..1767 4655 THYMU20081490
2213 127..>2055 4656 THYMU20095960 2214 304..945 4657
THYMU20100410 2215 219..1415 4658 THYMU20101610 2216 1087..1446
4659 THYMU20101920 2217 765..1310 4660 THYMU20105190 2218 850..1713
4661 THYMU20106710 2219 89..493 4662 THYMU20108310 2220 97..642
4663 THYMU20111180 2221 33..1367 4664 THYMU20111420 2222 914..1303
4665 THYMU20111830 2223 38..796 4666 THYMU20114470 2224 122..502
4667 THYMU20115850 2225 1500..1805 4668 THYMU20118060 2226 355..687
4669 THYMU20118520 2227 220..567 4670 THYMU20119390 2228 118..525
4671 THYMU20122730 2229 343..1140 4672 THYMU20126900 2230 163..1446
4673 THYMU20128070 2231 2..349 4674 THYMU20128260 2232 76..411 4675
THYMU20130890 2233 221..757 4676
THYMU20141670 2234 196..1152 4677 THYMU20142040 2235 24..653 4678
THYMU20142970 2236 495..1499 4679 THYMU20143270 2237 524..1549 4680
THYMU20147770 2238 80..1501 4681 THYMU20153160 2239 1303..1920 4682
THYMU20158250 2240 117..488 4683 THYMU20159430 2241 79..1581 4684
THYMU20161640 2242 110..679 4685 THYMU20162190 2243 299..646 4686
THYMU20169680 2244 718..1395 4687 THYMU20172150 2245 375..956 4688
THYMU20173980 2246 355..813 4689 THYMU20180280 2247 1352..1699 4690
THYMU20186390 2248 461..1495 4691 THYMU20186730 2249 194..535 4692
THYMU20187720 2250 284..661 4693 THYMU20193640 2251 659..1165 4694
THYMU20194360 2252 257..955 4695 THYMU20194420 2253 1080..1403 4696
THYMU20195990 2254 344..673 4697 THYMU20201980 2255 1094..2023 4698
THYMU20202890 2256 935..2188 4699 THYMU20204160 2257 654..1199 4700
THYMU20204990 2258 65..385 4701 THYMU20208300 2259 144..542 4702
THYMU20209590 2260 193..2061 4703 THYMU20215090 2261 862..1380 4704
THYMU20215970 2262 1004..1552 4705 THYMU20216840 2263 605..2074
4706 THYMU20222890 2264 1896..2198 4707 THYMU20226600 2265
246..1232 4708 THYMU20228540 2266 109..426 4709 THYMU20229220 2267
259..894 4710 THYMU20232090 2268 111..539 4711 THYMU20235760 2269
357..674 4712 THYMU20239000 2270 44..1672 4713 THYMU20239430 2271
656..982 4714 THYMU20240710 2272 680..2077 4715 THYMU20241210 2273
77..511 4716 THYMU20241850 2274 63..890 4717 THYMU20246840 2275
110..415 4718 THYMU20247480 2276 4..1176 4719 THYMU20250420 2277
222..707 4720 THYMU20251890 2278 1433..1777 4721 THYMU20253250 2279
713..1540 4722 THYMU20255570 2280 882..1550 4723 THYMU20255720 2281
88..645 4724 THYMU20259090 2282 1763..2092 4725 THYMU20265300 2283
60..1949 4726 THYMU20271250 2284 681..1628 4727 THYMU20272490 2285
174..560 4728 THYMU20277390 2286 930..1541 4729 THYMU20279750 2287
716..1114 4730 THYMU20283790 2288 253..804 4731 THYMU20284120 2289
178..525 4732 THYMU20286290 2290 287..1981 4733 THYMU20286320 2291
1214..1594 4734 TKIDN10000010 2292 386..838 4735 TKIDN20004640 2293
549..1172 4736 TKIDN20005210 2294 294..1133 4737 TKIDN20030590 2295
143..1558 4738 TKIDN20030620 2296 25..531 4739 TKIDN20047480 2297
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TRACH20033230 2311 560..2110 4754 TRACH20034840 2312 1985..>3328
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4763 TRACH20067620 2321 166..603 4764 TRACH20068660 2322 63..890
4765 TRACH20068700 2323 144..1811 4766 TRACH20069180 2324 63..1625
4767 TRACH20076740 2325 779..1669 4768 TRACH20076760 2326
1737..2183 4769 TRACH20077540 2327 1859..2455 4770 TRACH20079690
2328 144..2144 4771 TRACH20082780 2329 1675..2103 4772
TRACH20084720 2330 38..1819 4773 TRACH20085400 2331 223..2346 4774
TRACH20085830 2332 41..1567 4775 TRACH20091230 2333 1660..2067 4776
TRACH20092680 2334 56..457 4777 TRACH20096610 2335 417..935 4778
TRACH20099340 2336 156..494 4779 TRACH20105870 2337 1418..2176 4780
TRACH20107710 2338 13..474 4781 TRACH20109650 2339 1421..1849 4782
TRACH20111130 2340 1548..1937 4783 TRACH20115740 2341 507..893 4784
TRACH20118940 2342 1781..2083 4785 TRACH20121380 2343 795..1808
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4802 TRACH20167220 2360 986..2422 4803 TRACH20168350 2361 200..589
4804 TRACH20169800 2362 1922..2359 4805 TRACH20180840 2363
1288..1593 4806 TRACH20183170 2364 1029..2252 4807 TRACH20184490
2365 214..1596 4808 TRACH20187180 2366 1322..1639 4809
TRACH20190240 2367 1624..2313 4810 TSTOM10001860 2368 96..1859 4811
TSTOM20001390 2369 241..1671 4812 TSTOM20003150 2370 103..1245 4813
TSTOM20005690 2371 370..1626 4814 TUTER20002830 2372 172..930 4815
UMVEN10001560 2373 130..669 4816 UMVEN10001860 2374 198..>2048
4817 UMVEN20000690 2375 6..1118 4818 UMVEN20003540 2376 4..519 4819
UTERU20000740 2377 2062..2400 4820 UTERU20004240 2378 38..385 4821
UTERU20006290 2379 101..406 4822 UTERU20006960 2380 106..555 4823
UTERU20020010 2381 54..431 4824 UTERU20022940 2382 735..1232 4825
UTERU20030570 2383 184..1737 4826 UTERU20040610 2384 92..409 4827
UTERU20046640 2385 15..2699 4828 UTERU20046980 2386 216..926 4829
UTERU20050690 2387 619..924 4830 UTERU20054460 2388 557..>2294
4831 UTERU20055330 2389 45..632 4832 UTERU20055480 2390 92..1765
4833 UTERU20055930 2391 90..869 4834 UTERU20056010 2392 65..484
4835 UTERU20059050 2393 809..1459 4836 UTERU20061030 2394 994..1389
4837 UTERU20064000 2395 153..479 4838 UTERU20064860 2396 26..1780
4839 UTERU20065930 2397 37..2097 4840 UTERU20067050 2398 641..952
4841 UTERU20068990 2399 945..1319 4842 UTERU20070040 2400 36..383
4843 UTERU20070810 2401 761..1219 4844 UTERU20076390 2402 71..499
4845 UTERU20081300 2403 2063..2464 4846 UTERU20084260 2404
494..1321 4847 UTERU20094350 2405 293..802 4848 UTERU20095380 2406
872..1213 4849 UTERU20095400 2407 737..1456 4850 UTERU20097760 2408
1232..1759 4851 UTERU20099720 2409 201..746 4852 UTERU20101240 2410
210..602 4853 UTERU20114100 2411 538..963 4854 UTERU20115740 2412
469..933 4855 UTERU20116570 2413 327..1694 4856 UTERU20118110 2414
87..485 4857 UTERU20118970 2415 229..549 4858 UTERU20119060 2416
1192..2436 4859 UTERU20119680 2417 676..1185 4860 UTERU20120310
2418 68..1066 4861 UTERU20124070 2419 368..733 4862 UTERU20126880
2420 524..1045 4863 UTERU20134910 2421 1070..1489 4864
UTERU20135860 2422 676..1965 4865 UTERU20143980 2423 68..370 4866
UTERU20144640 2424 231..1148 4867 UTERU20145480 2425 172..2193 4868
UTERU20146310 2426 114..1580 4869 UTERU20146680 2427 524..1045 4870
UTERU20150870 2428 47..499 4871 UTERU20151980 2429 220..981 4872
UTERU20158300 2430 342..686 4873 UTERU20158800 2431 161..1318 4874
UTERU20161570 2432 295..1209 4875 UTERU20164260 2433 54..890 4876
UTERU20168220 2434 835..1530 4877 UTERU20176130 2435 27..1184 4878
UTERU20176320 2436 108..1364 4879 UTERU20178100 2437 2178..2528
4880 UTERU20179880 2438 172..2379 4881 UTERU20183640 2439
2289..2828 4882 UTERU20185230 2440 125..1927 4883 UTERU20186740
2441 851..1156 4884 UTERU20188110 2442 125..1135 4885 UTERU20188810
2443 84..389 4886
[0036] Namely, primers used to synthesize polynucleotides can be
designed based on the nucleotide sequences of polynucleotides of
the present invention shown in SEQ ID NOs in the above Table 1.
When one intends to synthesize full-length cDNAs, an oligo dT
primer can be used as the 3'-end primer. The length of the primers
is usually 15-100 bp, and favorably between 15-35 bp. In case of LA
PCR, which is described below, the primer length of 25-35 bp may
provide a good result.
[0037] A method to design a primer that enables a specific
amplification based on the aimed nucleotide sequence is known to
those skilled in the art (Current Protocols in Molecular Biology,
Ausubel et al. edit, (1987) John Wiley & Sons, Section
6.1-6.4). In designing a primer based on the 5'-end sequence, the
primer is designed so as that, in principle, the amplification
products will include the translation start site. Accordingly, for
example, when the 5'-end primer is designed based on the nucleotide
sequence of 5' untranslated region (5'UTR), any part of the 5'-end,
which ensures the specificity to the cDNA of interest, can be
selected as the primer.
[0038] When synthesizing a full-length cDNA, the target nucleotide
sequence to be amplified can extend to several thousand bp in some
cDNA. However, it is possible to amplify such a long nucleotides by
using such as LA PCR (Long and Accurate PCR). It is advantageous to
use LA PCR when synthesizing long DNA. In LA PCR, in which a
special DNA polymerase having 3'->5' exonuclease activity is
used, misincorporated nucleotides can be removed. Accordingly,
accurate synthesis of the complementary strand can be achieved even
with a long nucleotide sequence. By using LA PCR, it is reported
that amplification of a nucleotide with 20 kb longer can be
achieved under desirable conditions (Takeshi Hayashi (1996)
Jikken-Igaku Bessatsu, "Advanced Technologies in PCR"
Youdo-sha).
[0039] A template DNA for synthesizing the full-length cDNA of the
present invention can be obtained by using cDNA libraries that are
prepared by various methods. The full-length cDNA clones of the
present invention are clones with high probability of completeness
in length, which were obtained by the method comprising the steps
of [1] preparing libraries containing cDNAs with the very high
fullness ratio by oligo-capping, and [2] assembling the 5'-end
sequences and selecting one with the highest probability of
completeness in length in the cluster formed (there are many clones
longer in the 5'-end direction).
[0040] However, the uses of primers designed based on the
full-length nucleotide sequences provided by the present invention
enable easily obtaining full-length cDNAs without such a special
technique.
[0041] The problem with the cDNA libraries prepared by the known
methods or commercially available is that mRNA contained in the
libraries has very low fullness ratio. Thus, it is difficult to
screen full-length cDNA clone directly from the library using
ordinary cloning methods. The present invention has revealed a
nucleotide sequence of novel full-length cDNA. If a full-length
nucleotide sequence is provided, it is possible to synthesize a
target full-length cDNA by using enzymatic reactions such as PCR.
In particular, a full-length-enriched cDNA library, synthesized by
methods such as oligo-capping, is desirable to synthesize a
full-length cDNA with more reliability.
[0042] The 5'-end sequence of the full-length cDNA clones of the
invention can be used to isolate the regulatory element of
transcription including the promoter on the genome. A rough draft
of the human genome (analysis of human genomic sequence with lower
accuracy), which covers 90% of the genome, has been reported
(Nature, Vol. 409, 814-823, 2001), and by the year 2003, analysis
of the entire human genomic sequence is going to be finished.
However, it is hard to analyze with software the transcription
start sites on the human genome, in which long introns exist. By
contrast, it is easy to specify the transcription start site on the
genomic sequence using the nucleotide sequence which includes the
5'-end of the full-length cDNA clone of the present invention, and
thus it is easy to obtain the genomic region involved in
transcription regulation, which includes the promoter that is
contained in the upstream of the transcription start site.
[0043] The polypeptide encoded by the full-length cDNA of the
invention can be prepared as a recombinant polypeptide or as a
natural polypeptide. For example, the recombinant polypeptide can
be prepared by inserting the polynucleotide encoding the
polypeptide of the invention into a vector, introducing the vector
into an appropriate host cell and purifying the polypeptide
expressed within the transformed host cell, as described below. In
contrast, the natural polypeptide can be prepared, for example, by
utilizing an affinity column to which an antibody against the
polypeptide of the invention (Current Protocols in Molecular
Biology (1987) Ausubel et al. edit, John Wiley & Sons, Section
16.1-16.19) is attached. The antibody used for affinity
purification may be either a polyclonal antibody, or a monoclonal
antibody. Alternatively, in vitro translation (See, for example,
"On the fidelity of mRNA translation in the nuclease-treated rabbit
reticulocyte lysate system." Dasso M. C., and Jackson R. J. (1989)
Nucleic Acids Res. 17: 3129-3144) may be used for preparing the
polypeptide of the invention.
[0044] Polypeptides functionally equivalent to the polypeptides of
the present invention can be prepared based on the activities,
which were clarified in the above-mentioned manner, of the
polypeptides of the present invention. Using the biological
activity possessed by the polypeptide of the invention as an index,
it is possible to verify whether or not a particular polypeptide is
functionally equivalent to the polypeptide of the invention by
examining whether or not the polypeptide has said activity.
[0045] Polypeptides functionally equivalent to the polypeptides of
the present invention can be prepared by those skilled in the art,
for example, by using a method for introducing mutations into an
amino acid sequence of a polypeptide (for example, site-directed
mutagenesis (Current Protocols in Molecular Biology, edit, Ausubel
et al., (1987) John Wiley & Sons, Section 8.1-8.5) Besides,
such polypeptides can be generated by spontaneous mutations. The
present invention also includes a polypeptide comprising the amino
acid sequence shown in Table 1 in which one or more amino acids are
substituted, deleted, inserted, and/or added, as long as the
polypeptides have the equivalent functions to those of the
polypeptides identified in the present Examples described
later.
[0046] There are no limitations on the number and sites of amino
acid mutations, as long as the polypeptides maintain the functions
thereof. The number of mutations typically corresponds to 30% or
less, or 20% or less, or 10% or less, preferably 5% or less, or 3%
or less of the total amino acids, more preferably 2% or less or 1%
or less of the total amino acids. Alternatively, herein,
substitution of one or more amino acids includes substitution of
several amino acids. As used herein, the term "several amino acids"
means, for example, 5 amino acids, preferably 4 or 3 amino acids,
more preferably 2 amino acids, and further preferably 1 amino
acid.
[0047] From the viewpoint of maintaining the polypeptide function,
it is preferable that a substituted amino acid has a similar
property to that of the original amino acid. For example, Ala, Val,
Leu, Ile, Pro, Met, Phe and Trp are assumed to have similar
properties to one another because they are all classified into a
group of non-polar amino acids. Similarly, substitution can be
performed among non-charged amino acid such as Gly, Ser, Thr, Cys,
Tyr, Asn, and Gln, acidic amino acids such as Asp and Glu, and
basic amino acids such as Lys, Arg, and His.
[0048] In addition, polypeptides functionally equivalent to the
polypeptides of the present invention can be isolated by using
techniques of hybridization or gene amplification known to those
skilled in the art. Specifically, using the hybridization technique
(Current Protocols in Molecular Biology, edit, Ausubel et al.,
(1987) John Wiley & Sons, Section 6.3-6.4)), those skilled in
the art can usually isolate a polynucleotide highly homologous to
the polynucleotide encoding the polypeptide identified in the
present Example based on the identified nucleotide sequence (Table
1) or a portion thereof and obtain the functionally equivalent
polypeptide from the isolated polynucleotide. The present invention
include polypeptides encoded by the polynucleotides hybridizing
with the polynucleotides encoding the polypeptides identified in
the present Example, as long as the polypeptides are functionally
equivalent to the polypeptides identified in the present Example.
Organisms from which the functionally equivalent polypeptides are
isolated are illustrated by vertebrates such as human, mouse, rat,
rabbit, pig and bovine, but are not limited to these animals.
[0049] Washing conditions of hybridization for the isolation of
polynucleotides encoding the functionally equivalent polypeptides
are usually "1.times.SSC, 0.1% SDS, 37.degree. C."; more stringent
conditions are "0.5.times.SSC, 0.1% SDS, 42.degree. C."; and still
more stringent conditions are "0.1.times.SSC, 0.1% SDS, 65.degree.
C.". Alternatively, the following conditions can be given as
hybridization conditions of the present invention. Namely,
conditions in which the hybridization is done at "6.times.SSC, 40%
Formamide, 25.degree. C.", and the washing at "1.times.SSC,
55.degree. C." can be given. More preferable conditions are those
in which the hybridization is done at "6.times.SSC, 40% Formamide,
37.degree. C.", and the washing at "0.2.times.SSC, 55.degree. C.".
Even more preferable are those in which the hybridization is done
at "6.times.SSC, 50% Formamide, 37.degree. C.", and the washing at
"0.1.times.SSC, 62.degree. C.". The more stringent the conditions
of hybridization are, the more frequently the polynucleotides
highly homologous to the probe sequence are isolated. Therefore, it
is preferable to conduct hybridization under stringent conditions.
Examples of stringent conditions in the present invention are,
washing conditions of "0.5.times.SSC, 0.1% SDS, 42.degree. C.", or
alternatively, hybridization conditions of "6.times.SSC, 40%
Formamide, 37.degree. C.", and the washing at "0.2.times.SSC,
55.degree. C.".
[0050] One skilled in the art can suitably select various
conditions, such as dilution ratios of SSC, formamide
concentrations, and temperatures to accomplish a similar
stringency.
[0051] However, the above-mentioned combinations of SSC, SDS and
temperature conditions are indicated just as examples. Those
skilled in the art can select the hybridization conditions with
similar stringency to those mentioned above by properly combining
the above-mentioned or other factors (for example, probe
concentration, probe length and duration of hybridization reaction)
that determines the stringency of hybridization.
[0052] The amino acid sequences of polypeptides isolated by using
the hybridization techniques usually have high identity to those of
the polypeptides of the present invention, which are shown in Table
1. The present invention encompasses a polynucleotide comprising a
nucleotide sequence that has a high identity to the nucleotide
sequence of claim 1(a). Furthermore, the present invention
encompasses a peptide, or polypeptide comprising an amino acid
sequence that has a high identity to the amino acid sequence
encoded by the polynucleotide of claim 1(b). The term "high
identity" indicates sequence identity of at least 40% or more;
preferably 60% or more; and more preferably 70% or more.
Alternatively, more preferable is identity of 90% or more, or 93%
or more, or 95% or more, furthermore, 97% or more, or 99% or more.
The identity can be determined by using the BLAST search
algorithm.
[0053] As used herein, "percent identity" of amino acid sequences
or nucleic acids is determined using the algorithm BLAST of Karlin
and Altschul (Proc. Natl. Acad. Sci. USA 90:5873-5877, 1993). Such
an algorithm is incorporated into the BLASTN and BLASTX programs of
Altschul et al. (J. Mol. Biol.215:403-410, 1990). BLAST nucleotide
searches are performed with the BLASTN program, for example,
score=100, wordlength=12. BLAST protein searches are performed with
the BLASTX program, for example, score=50, wordlength=3. When
utilizing BLAST and Gapped BLAST programs, the default parameters
of the respective programs are used. See
http://www.ncbi.nlm.nih.gov.
[0054] With the gene amplification technique (PCR) (Current
Protocols in Molecular Biology, edit, Ausubel et al., (1987) John
Wiley & Sons, Section 6.1-6.4)) using primers designed based on
the nucleotide sequence (Table 1) or a portion thereof identified
in the present Example, it is possible to isolate a polynucleotide
fragment highly homologous to the polynucleotide sequence or a
portion thereof and to obtain functionally equivalent polypeptide
to a particular polypeptide identified in the present Example based
on the isolated polynucleotide fragment.
[0055] The present invention also provides a polynucleotide
containing at least 15 nucleotides complementary to a
polynucleotide comprising a nucleotide sequence of SEQ ID NOs shown
in Table 1 or the complementary strand thereof. Herein, the term
"complementary strand" is defined as one strand of a double strand
DNA composed of A:T and G:C base pair to the other strand. Also,
"complementary" is defined as not only those completely matching
within a continuous region of at least 15 nucleotides, but also
having a identity of at least 70%, favorably 80% or higher, more
favorably 90% or higher, and most favorably 95% or higher within
that region. The identity may be determined using the algorithm
described herein.
[0056] Such a polynucleotide includes probes and primers used for
the detection and amplification of a polynucleotide encoding the
inventive polypeptide. When used as a primer, the polynucleotide
usually comprises 15 to 100 bp, and preferably of 15 to 35 bp. When
used as a probe, the polynucleotide comprises the whole or a part
of the sequence of a polynucleotide of the invention, and comprises
at least 15 bp. When used as primers, such polynucleotides are
complementary at the 3'-end, and restriction enzyme recognition
sequences or tags can be added to the 5'-end.
[0057] Furthermore, polynucleotides of the present invention
include an antisense polynucleotide for suppressing the expression
of a polypeptide of the invention, which comprises an amino acid
sequence of SEQ ID NOs shown in Table 1. To exert an antisense
effect, an antisense polynucleotide has at least 15 bp or more, for
example 50 bp or more, preferably 100 bp or more, and more
preferably 500 bp or more, and usually has 3000 bp or less, and
preferably 2000 bp or less. Antisense polynucleotides can be used
in the gene therapy of diseases caused by abnormalities of the
polypeptides of the invention (abnormal function or abnormal
expression). An antisense polynucleotide can be prepared, for
example, by the phosphorothioate method ("Physicochemical
properties of phosphorothioate oligodeoxynucleotides." Stein (1988)
Nucleic Acids Res. 16: 3209-3221) based on the sequence information
of polynucleotide encoding a polypeptide of the invention (for
example, the nucleotide sequences of SEQ ID NO: 1 to 2443).
[0058] The polynucleotides or antisense polynucleotides of the
present invention can be used in, for example, gene therapy. As
target diseases, for example, cancers or various inflammatory
diseases may be preferable. These molecules can be used for gene
therapy, for example, by administrating them to patients by the in
vivo or ex vivo method using virus vectors such as retrovirus
vectors, adenovirus vectors, and adeno-related virus vectors, or
non-virus vectors such as liposomes.
[0059] The present invention also includes a partial peptide of the
polypeptides of the invention. The partial peptide comprises a
polypeptide generated as a result that a signal peptide has been
removed from a secretory protein. If the polypeptide of the present
invention has an activity as a receptor or a ligand, the partial
peptide may function as a competitive inhibitor of the polypeptide
and may bind to the receptor (or ligand). In addition, the present
invention includes an antigen peptide for raising antibodies. For
the peptides to be specific for the polypeptide of the invention,
the peptides comprise at least 7 amino acids, preferably 8 amino
acids or more, more preferably 9 amino acids or more, and even more
preferably 10 amino acids or more. The peptide can be used for
preparing antibodies against the polypeptide of the invention, or
competitive inhibitors of them, and also screening for a receptor
that binds to the polypeptide of the invention. The partial
peptides of the invention can be produced, for example, by genetic
engineering methods, known methods for synthesizing peptides, or
digesting the polypeptide of the invention with an appropriate
peptidase.
[0060] The present invention also relates to a vector into which a
polynucleotide of the invention is inserted. The vector of the
invention is not limited as long as it contains the inserted
polynucleotide stably. For example, if E. coli is used as a host,
vectors such as pBluescript vector (Stratagene) are preferable as a
cloning vector. To produce the polypeptide of the invention,
expression vectors are especially useful. Any expression vector can
be used as long as it is capable of expressing the polypeptide in
vitro, in E. coli, in cultured cells, or in vivo. For example,
PBEST vector (Promega) is preferable for in vitro expression, pET
vector (Invitrogen) for E. coli, pME18S-FL3 vector (GenBank
Accession No. AB009864) for cultured cells, and pME18S vector (Mol.
Cell. Biol. (1988) 8: 466-472) for in vivo expression. To insert
the polynucleotide of the invention, ligation utilizing restriction
sites can be performed according to the standard method (Current
Protocols in Molecular Biology (1987) Ausubel et al. edit, John
Wiley & Sons, Section 11.4-11.11).
[0061] Recently, the technique of GATEWAY.TM. system (Invitrogen),
which is an expression vector construction system for polypeptide
expression, has been developed (Experimental Medicine, Vol. 18, No.
19 (December), p2716-2717, 2000). This system includes two types of
site-specific recombinases (BP CLONASE.TM. and LR CLONASE.TM.)
derived from lambda phage and uses BP CLONASE.TM.-specific
recombination sites for an Entry Vector and LR CLONASE.TM.-specific
recombination sites for a Destination Vector, which may comprise a
tag useful for polypeptide purification. With this system, an
expression vector can be obtained by using homologous
recombination.
[0062] First, a polynucleotide fragment of interest is inserted
into the entry vector using the first recombination. Then, the
secondary recombination is allowed to take place between the entry
vector, where the polynucleotide fragment of interest has been
inserted, and the destination vector. Thus, the expression vector
can be prepared rapidly and highly efficiently. With the
above-mentioned typical method using restriction enzyme and ligase
reactions, the step of expression vector construction and
expression of polypeptide of interest takes about 7 to 10 days.
However, with the GATEWAY.TM. system, the polypeptide of interest
can be expressed and prepared in only 3 to 4 days. Thus, the system
ensures a high-throughput functional analysis for expressed
polypeptides
(http://biotech.nikkeibp.co.jp/netlink/lto/gateway/).
[0063] The present invention also relates to a transformant
carrying the vector of the invention. Any cell can be used as a
host into which the vector of the invention is inserted, and
various kinds of host cells can be used depending on the purposes.
For strong expression of the polypeptide in eukaryotic cells, COS
cells or CHO cells can be used, for example.
[0064] Introduction of the vector into host cells can be performed,
for example, by calcium phosphate precipitation method,
electroporation method (Current Protocols in Molecular Biology
(1987) Ausubel et al. edit, John Wiley & Sons, Section
9.1-9.9), lipofectamine method (GIBCO-BRL), or microinjection
method, etc.
[0065] Further, a polynucleotide containing at least 15 nucleotides
comprising a nucleotide sequence of any one of the polynucleotides
comprising the nucleotide sequences of SEQ ID NOs shown in Table 1
or the complementary strand thereof can be used not only as a
primer for synthesizing full-length cDNAs but also for testing and
diagnosing the abnormalities of the polypeptide encoded by the
full-length cDNA of the present invention. For example, by
utilizing polymerase chain reaction (genomic DNA-PCR, or RT-PCR)
using the polynucleotide of the invention as a primer,
polynucleotide encoding the polypeptide of the invention can be
amplified. It is also possible to obtain the regulatory region of
expression in the 5'-upstream by using PCR or hybridization since
the transcription start site within the genomic sequence can be
easily specified based on the 5'-end sequence of the full-length
cDNA. The obtained genomic region can be used for detection and/or
diagnosis of the abnormality of the sequence by RFLP analysis,
SSCP, or sequencing. Especially, in the case where expression of
the mRNA of the present invention varies according to a specific
disease, analysis of the amount of expression of the mRNA using the
polynucleotide of the present invention as a probe or a primer
enables detection and diagnosis of the disease.
[0066] The present invention also relates to antibodies that bind
to the polypeptide of the invention. There are no limitations in
the form of the antibodies of the invention. They include
polyclonal antibodies, monoclonal antibodies, or their portions
that can bind to an antigen. They also include antibodies of all
classes. Furthermore, special antibodies such as humanized
antibodies and chimeric antibodies are also included.
[0067] The polyclonal antibody of the invention can be obtained
according to the standard method by synthesizing an oligopeptide
corresponding to the amino acid sequence and immunizing rabbits
with the peptide (Current Protocols in Molecular Biology (1987)
Ausubel et al. edit, John Wiley & Sons, Section 11.12-11.13).
The monoclonal antibody of the invention can be obtained according
to the standard method by purifying the polypeptide expressed in E.
coli, immunizing mice with the polypeptide, and producing a
hybridoma cell by fusing the spleen cells and myeloma cells
(Current Protocols in Molecular Biology (1987) Ausubel et al. edit,
John Wiley & Sons, Section 11.4-11.11).
[0068] The antibody binding to the polypeptide of the present
invention can be used for purification of the polypeptide of the
invention, and also for detection and/or diagnosis of the
abnormalities of the expression and structure of the polypeptide.
Specifically, polypeptides can be extracted, for example, from
tissues, blood, or cells, and the polypeptide of the invention is
detected by Western blotting, immunoprecipitation, or ELISA, etc.
for the above purpose.
[0069] Furthermore, the antibody binding to the polypeptide of the
present invention can be utilized for treating the diseases that
associates with the polypeptide of the invention. If the antibodies
are used for treating patients, human antibodies, humanized
antibodies, or chimeric antibodies are preferable in terms of their
low antigenicity. The human antibodies can be prepared by
immunizing a mouse whose immune system is replaced with that of
human (e.g., see "Functional transplant of megabase human
immunoglobulin loci recapitulates human antibody response in mice"
Mendez, M. J. et al. (1997) Nat. Genet. 15: 146-156). The humanized
antibodies can be prepared by recombination of the hypervariable
region of a monoclonal antibody (Methods in Enzymology (1991) 203:
99-121).
[0070] A cDNA of the present invention encodes, for example, an
amino acid sequence of a protein that is predicted to have the
following function. The use of the amino acid sequences of the
polypeptides encoded by the cDNAs of the present invention enables
predicting that the polypeptides have the following functions. It
can be predict, from the results of homology search of SwissProt,
GenBank, UniGene, or nr, that these polypeptides have such
functions. Specifically, for instance, as shown in Examples,
searching for a known gene or polypeptide that is homologous to the
partial sequence of the full-length cDNA of the invention (2443
clone) and referring the function of the gene and of the
polypeptide encoded by the gene make it possible to predict the
function of the polypeptide encoded by the cDNA of the invention.
In this way, each of 1216 clones out of the 2443 full-length cDNA
clones of the invention was predicted to encode a polypeptide that
was classified into the following categories.
[0071] Secretory and/or membrane protein (632 clones)
[0072] Glycoprotein-related protein (128 clones)
[0073] Signal transduction-related protein (84 clones)
[0074] Transcription-related protein (144 clones)
[0075] Disease-related protein (387 clones)
[0076] Enzyme and/or metabolism-related protein (206 clones)
[0077] Cell division- and/or cell proliferation-related protein (33
clones)
[0078] Cytoskeleton-related protein (75 clones)
[0079] Nuclear protein and/or RNA synthesis-related protein (65
clones)
[0080] Protein synthesis- and/or transport-related protein (62
clones)
[0081] Cellular defense-related protein (15 clones)
[0082] Development and/or differentiation-related protein (13
clones)
[0083] DNA- and/or RNA-binding protein (174 clones)
[0084] ATP- and/or GTP-binding protein (68 clones)
[0085] The functions of the polypeptides encoded by the cDNAs of
the present invention can be predicted by assessing the presence of
signal sequence, transmembrane region, nuclear translocation
signal, glycosylation signal, phosphorylation site, and zinc finger
motif, SH3 domain, etc. in the amino acid sequences. The programs,
PSORT (Nakai K., and Kanehisa M. (1992) Genomics 14: 897-911),
SOSUI (Hirokawa T. et al. (1998) Bioinformatics 14: 378-379)
(Mitsui Knowledge Industry), and MEMSAT (Jones D. T., Taylor W. R.,
and Thornton J. M. (1994) Biochemistry 33: 3038-3049) can be used
to predict the existence of the signal sequence or transmembrane
region. Alternatively, a partial amino acid sequence of the
polypeptide is fused with another polypeptide such as GFP, the
fusion polypeptide is transfected into cultured cells, and the
localization is analyzed to predict the function of the original
polypeptide.
[0086] Based on the determined nucleotide sequences of the
full-length cDNAs obtained in the present invention, it is possible
to predict more detailed functions of the polypeptides encoded by
the cDNA clones, for example, by searching the databases such as
GenBank, Swiss-Prot, UniGene, and nr for homologies of the cDNAs;
or by searching the amino acid sequences deduced from the
full-length cDNAs for signal sequences by using software programs
such as PSORT, for transmembrane regions by using software programs
such as SOSUI or for motifs by using software programs such as Pfam
(http://www.sanger.ac.uk/Software/Pfam/index.shtml) and PROSITE
(http://www.expasy.ch/prosite/). As a matter of course, the
functions are often predictable by using partial sequence
information (preferably 300 nucleotides or more) instead of the
full-length nucleotide sequences. However, the result of the
prediction by using partial nucleotide sequence does not always
agree with the result obtained by using full-length nucleotide
sequence, and thus, it is needless to say that the prediction of
function is preferably performed based on the full-length
nucleotide sequences.
[0087] GenBank, Swiss-Prot, UniGene and nr databases were searched
for homologies of the full-length nucleotide sequences of the 2443
clones (see Example 6). The amino acid sequences deduced from the
full-length nucleotide sequences were searched for functional
domains by PSORT, SOSUI and Pfam. Prediction of functions of
polypeptides encoded by the clones and the categorization thereof
were performed based on these results obtained. The categorization
was carried out by the following method.
[0088] [1] Firstly, the cDNA clones were classified into the
above-mentioned 14 functional categories based on the results of
annotation-based categorization (using the keywords in the case of
Swiss-Prot hit data; using Definition or Reference information in
the case of GenBank, UniGene, or nr hit data), and the signal
sequence search of the deduced ORFs by PSORT and the transmembrane
region search by SOSUI.
[0089] [2] Secondly, clones which had been unassignable to the
categories by the method of [1] were searched for functional
domains and/or motifs by Pfam. Based on the results, the clones
were additionally classified into the above-mentioned 14 types of
categories when they had a functional domain and/or motif
assignable to any one of the categories.
[0090] The following 632 clones presumably belong to secretory
and/or membrane proteins.
[0091] ADIPS10000640, ADRGL10001470, ADRGL20013520, ADRGL20018540,
ADRGL20035850, ASTRO20001410, ASTRO20005330, ASTRO20033160,
ASTRO20055750, ASTRO20058630, ASTRO20190390, BEAST20004540,
BGGI110000240, BNGH420088500, BRACE20006400, BRACE20038000,
BRACE20038470, BRACE20039040, BRACE20039540, BRACE20051380,
BRACE20053630, BRACE20059370, BRACE20060550, BRACE20061050,
BRACE20063630, BRACE20067430, BRACE20069090, BRACE20081720,
BRACE20101700, BRACE20101710, BRACE20116110, BRACE20147800,
BRACE20153680, BRACE20163350, BRACE20179340, BRACE20188470,
BRACE20195100, BRACE20201570, BRACE20210140, BRACE20224480,
BRACE20224500, BRACE20228480, BRACE20232840, BRACE20238000,
BRACE20273890, BRACE20274080, BRALZ20013500, BRALZ20054710,
BRALZ20064740, BRALZ20069760, BRALZ20073760, BRALZ20077930,
BRAMY20000860, BRAMY20002770, BRAMY20025840, BRAMY20039260,
BRAMY20060920, BRAMY20063970, BRAMY20111960, BRAMY20112800,
BRAMY20124260, BRAMY20134140, BRAMY20135900, BRAMY20136210,
BRAMY20144620, BRAMY20152110, BRAMY20174550, BRAMY20181220,
BRAMY20195090, BRAMY20211390, BRAMY20211420, BRAMY20215230,
BRAMY20218250, BRAMY20218670, BRAMY20229800, BRAMY20231720,
BRAMY20247280, BRAMY20252180, BRAMY20273960, BRAMY20277170,
BRAMY20284910, BRAMY20285160, BRAWH20015350, BRAWH20015890,
BRAWH20016860, BRAWH20018730, BRAWH20030250, BRAWH20064050,
BRAWH20110790, BRAWH20112940, BRAWH20117950, BRAWH20118230,
BRAWH20121640, BRAWH20122580, BRAWH20132190, BRCAN20064010,
BRCAN20071190, BRCAN20091560, BRCAN20103740, BRCAN20224720,
BRCAN20273550, BRCAN20280360, BRCAN20285450, BRCOC10000870,
BRCOC20004040, BRCOC20006370, BRCOC20041750, BRCOC20077690,
BRCOC20078640, BRCOC20090520, BRCOC20101230, BRCOC20107300,
BRCOC20114180, BRCOC20121720, BRCOC20134480, BRCOC20136750,
BRHIP10001290, BRHIP20000870, BRHIP20003120, BRHIP20103090,
BRHIP20111200, BRHIP20118380, BRHIP20118910, BRHIP20121410,
BRHIP20135100, BRHIP20174040, BRHIP20179200, BRHIP20183690,
BRHIP20191490, BRHIP20191770, BRHIP20198190, BRHIP20207430,
BRHIP20208270, BRHIP20208590, BRHIP20217620, BRHIP20233090,
BRHIP20234380, BRHIP20238880, BRHIP20283030, BRHIP30004570,
BRSSN20003120, BRSSN20043040, BRSSN20066110, BRSSN20120810,
BRSSN20137020, BRSSN20142940, BRSSN20146100, BRSSN20151990,
BRSSN20169050, BRSTN20002200, BRTHA20004740, BRTHA20046290,
BRTHA20046420, COLON10001350, COLON20093370, CTONG10000100,
CTONG10000940, CTONG10001650, CTONG20004690, CTONG20009770,
CTONG20092570, CTONG20092580, CTONG20095340, CTONG20099380,
CTONG20103480, CTONG20105080, CTONG20114740, CTONG20119200,
CTONG20120770, CTONG20124730, CTONG20131490, CTONG20132220,
CTONG20133480, CTONG20139340, CTONG20149950, CTONG20155400,
CTONG20158660, CTONG20159530, CTONG20161850, CTONG20267700,
D3OST10001090, D3OST20036070, D3OST20038560, D3OST30002580,
D6OST20005070, D9OST20002780, D9OST20015470, D9OST20023970,
D9OST20026730, D9OST20035940, D9OST20040180, DFNES20025880,
FCBBF10000240, FCBBF10000380, FCBBF10001150, FCBBF10001210,
FCBBF10001550, FCBBF10002430, FCBBF10002700, FCBBF10003220,
FCBBF10003760, FCBBF10005460, FCBBF10005740, FCBBF20032970,
FCBBF20042560, FCBBF20049300, FCBBF20051220, FCBBF30008470,
FCBBF30024750, FCBBF30078290, FCBBF30083620, FCBBF30086440,
FCBBF30090690, FCBBF30095260, FCBBF30123470, FCBBF30172550,
FCBBF30175310, FCBBF30190850, FCBBF30215060, FCBBF30238870,
FCBBF30251420, FCBBF30279030, FEBRA20002100, FEBRA20004620,
FEBRA20009090, FEBRA20029860, FEBRA20037260, FEBRA20080810,
FEBRA20086620, FEBRA20092890, FEBRA20093520, FEBRA20095880,
FEBRA20111460, FEBRA20125070, FEBRA20130190, FEBRA20140100,
FEBRA20145780, FEBRA20211710, FEBRA20223220, FEBRA20229630,
FEBRA20235500, HCHON20000380, HCHON20008180, HCHON20015980,
HCHON20016040, HCHON20016650, HCHON20040020, HCHON20064590,
HCHON20067700, HCHON20068710, HCHON20086720, HCHON20100740,
HEART20003060, HEART20005410, HEART20034320, HEART20049410,
HEART20049800, HEART20072310, HHDPC20001040, HHDPC20014320,
HHDPC20034720, HHDPC20068620, HHDPC20084140, HHDPC20091780,
HHDPC20092080, HLUNG10000550, KIDNE20003940, KIDNE20007770,
KIDNE20011400, KIDNE20021910, KIDNE20022620, KIDNE20100070,
KIDNE20101510, KIDNE20109730, KIDNE20121880, KIDNE20125630,
KIDNE20126010, KIDNE20126130, KIDNE20127450, KIDNE20130450,
KIDNE20131580, KIDNE20137340, KIDNE20181660, LIVER20035110,
LIVER20045650, LIVER20055200, LIVER20062510, LIVER20064690,
LIVER20075680, LIVER20087060, LIVER20091180, MESAN10001260,
MESAN20014500, MESAN20027090, MESAN20038510, MESAN20089360,
MESAN20103120, MESAN20115970, MESAN20125860, MESAN20139360,
MESAN20152770, MESAN20153910, MESAN20174170, NOVAR20000380,
NT2NE20010050, NT2NE20021620, NT2NE20068130, NT2NE20118960,
NT2NE20124480, NT2NE20131890, NT2NE20132170, NT2NE20155110,
NT2NE20156260, NT2NE20157470, NT2NE20159740, NT2NE20177520,
NT2NE20183760, NT2RI20003480, NT2RI20023910, NT2RI20025400,
NT2RI20028470, NT2RI20040930, NT2RI20054050, NT2RI20056700,
NT2RI20076290, NT2RI20086220, NT2RI20091940, NT2RI20244600,
NT2RP70072690, NT2RP70081610, NT2RP70122910, NT2RP70125160,
NT2RP70133740, NT2RP70134990, NT2RP70137290, NT2RP70179710,
NT2RP70188020, NT2RP70192730, NT2RP70198350, NTONG20028070,
NTONG20029700, NTONG20048060, NTONG20049910, NTONG20051530,
NTONG20061870, NTONG20063010, NTONG20067830, NTONG20076930,
NTONG20092330, OCBBF10001750, OCBBF20013890, OCBBF20019830,
OCBBF20023570, OCBBF20026630, OCBBF20046690, OCBBF20050770,
OCBBF20059560, OCBBF20063320, OCBBF20071210, OCBBF20072320,
OCBBF20080050, OCBBF20086400, OCBBF20086910, OCBBF20087010,
OCBBF20088140, OCBBF20091150, OCBBF20107090, OCBBF20108630,
OCBBF20116850, OCBBF20120390, OCBBF20122620, OCBBF20130910,
OCBBF20132850, OCBBF20145760, OCBBF20155060, OCBBF20178880,
OCBBF20180120, OCBBF20180840, OCBBF20188730, PANCR10000910,
PEBLM10000710, PEBLM20024320, PEBLM20040150, PEBLM20074370,
PEBLM20075980, PERIC20004220, PLACE60086400, PLACE60121080,
PLACE60161600, PLACE60177140, PROST20005050, PROST20050670,
PROST20107820, PROST20116600, PROST20120160, PROST20127800,
PROST20146010, PROST20164440, PROST20169800, PROST20170980,
PROST20175290, PUAEN20003740, PUAEN20030180, SALGL10001710,
SKMUS20003610, SKMUS20007800, SKMUS20011640, SKMUS20020840,
SKMUS20028210, SKMUS20028400, SKMUS20077400, SKNSH20028660,
SKNSH20031740, SKNSH20051940, SKNSH20063040, SMINT20009840,
SMINT20011990, SMINT20022020, SMINT20029760, SMINT20040860,
SMINT20050750, SMINT20053870, SMINT20073650, SMINT20095050,
SMINT20100680, SMINT20105330, SMINT20106720, SMINT20121950,
SMINT20127930, SMINT20144430, SMINT20144890, SMINT20153260,
SMINT20154540, SMINT20157450, SMINT20173240, SMINT20178550,
SMINT20191420, SMINT20192000, SPLEN20003070, SPLEN20021660,
SPLEN20029310, SPLEN20079510, SPLEN20095810, SPLEN20097330,
SPLEN20118300, SPLEN20141360, SPLEN20141990, SPLEN20142100,
SPLEN20144520, SPLEN20152760, SPLEN20157880, SPLEN20165310,
SPLEN20167200, SPLEN20169220, SPLEN20169720, SPLEN20171890,
SPLEN20172120, SPLEN20179810, SPLEN20186430, SPLEN20211570,
SPLEN20211940, SPLEN20213830, SPLEN20273950, SPLEN20292950,
SPLEN20293800, SPLEN20304950, SPLEN20329240, STOMA20005390,
STOMA20005670, STOMA20006400, STOMA20006780, STOMA20008880,
STOMA20051200, STOMA20056640, STOMA20056670, STOMA20062130,
STOMA20077450, STOMA20080500, STOMA20088380, STOMA20092530,
SYNOV20001520, SYNOV20001730, SYNOV20002510, SYNOV20002790,
SYNOV20002970, SYNOV20004260, SYNOV20007000, SYNOV20008240,
SYNOV20009230, SYNOV20010880, SYNOV20011110, SYNOV20013000,
SYNOV20013560, SYNOV20013900, SYNOV30001840, TBAES20003150,
TESOP20004000, TESOP20005690, TESTI20001720, TESTI20036380,
TESTI20037560, TESTI20094120, TESTI20110280, TESTI20123080,
TESTI20123560, TESTI20128350, TESTI20136100, TESTI20136710,
TESTI20143390, TESTI20148000, TESTI20164100, TESTI20193360,
TESTI20209810, TESTI20209990, TESTI20211220, TESTI20214250,
TESTI20216370, TESTI20230250, TESTI20231940, TESTI20242990,
TESTI20244190, TESTI20254220, TESTI20254860, TESTI20265970,
TESTI20271850, TESTI20272960, TESTI20284880, TESTI20291310,
TESTI20291960, TESTI20303220, TESTI20303360, TESTI20303420,
TESTI20307700, TESTI20309170, TESTI20314180, TESTI20316870,
TESTI20333000, TESTI20335200, TESTI20347180, TESTI20347300,
TESTI20352620, TESTI20357960, TESTI20370810, TESTI20373820,
TESTI20383880, TESTI20390260, TESTI20390410, TESTI20391770,
TESTI20393530, TESTI20396130, TESTI20397760, TESTI20401020,
TESTI20401280, TESTI20415170, TESTI20421490, TESTI20422640,
TESTI20441940, TESTI20442760, TESTI20444130, TESTI20444180,
TESTI20449200, TESTI20463520, TESTI20463580, TESTI20465350,
THYMU10005360, THYMU10005540, THYMU20027560, THYMU20032870,
THYMU20039810, THYMU20066100, THYMU20081490, THYMU20100410,
THYMU20106710, THYMU20111830, THYMU20141670, THYMU20147770,
THYMU20159430, THYMU20161640, THYMU20162190, THYMU20173980,
THYMU20194420, THYMU20208300, THYMU20216840, THYMU20222890,
THYMU20229220, THYMU20241850, THYMU20277390, TKIDN20005210,
TRACH20002870, TRACH20003590, TRACH20016210, TRACH20019960,
TRACH20029540, TRACH20033230, TRACH20034840, TRACH20042920,
TRACH20050040, TRACH20067620, TRACH20068660, TRACH20069180,
TRACH20076740, TRACH20085400, TRACH20085830, TRACH20109650,
TRACH20111130, TRACH20121380, TRACH20128110, TRACH20128230,
TRACH20134950, TRACH20136710, TRACH20139820, TRACH20140820,
TRACH20145440, TRACH20168350, TRACH20180840, TRACH20190240,
UMVEN20000690, UTERU20030570, UTERU20040610, UTERU20046980,
UTERU20055480, UTERU20064860, UTERU20076390, UTERU20094350,
UTERU20135860, UTERU20144640, UTERU20158300, UTERU20158800,
UTERU20161570, UTERU20178100, UTERU20183640, UTERU20186740
[0092] The following 128 clones presumably belong to
glycoprotein-related proteins. ADIPS10000640, BRACE20059370,
BRACE20163350, BRAMY20277170, BRAMY20285160, BRAWH20064050,
BRAWH20112940, BRAWH20117950, BRAWH20118230, BRCAN20103740,
BRCOC20004040, BRCOC20006370, BRHIP10001290, BRHIP20103090,
BRHIP20283030, BRHIP30004570, BRSSN20003120, BRSSN20146100,
BRTHA20046290, COLON10001350, CTONG20159530, D9OST20023970,
D9OST20040180, FCBBF10001150, FCBBF20049300, FCBBF30024750,
FCBBF30083620, FCBBF30190850, FCBBF30238870, FEBRA20086620,
FEBRA20092890, HCHON20015980, HCHON20016040, HCHON20064590,
HCHON20086720, HCHON20100740, HEART20003060, HHDPC20014320,
HHDPC20068620, HHDPC20092080, KIDNE20003940, KIDNE20007770,
KIDNE20101510, LIVER20064690, MESAN20125860, NT2NE20118960,
NT2NE20157470, NT2NE20177520, NT2RI20003480, NT2RI20056700,
NT2RP70192730, NTONG20051530, NTONG20076930, OCBBF20107090,
OCBBF20108630, OCBBF20120390, OCBBF20145760, OCBBF20155060,
PLACE60177140, SMINT20050750, SMINT20073650, SMINT20105330,
SMINT20106720, SMINT20112730, SMINT20127930, SMINT20153260,
SMINT20179740, SMINT20190170, SPLEN20021660, SPLEN20142100,
SPLEN20157880, SPLEN20165310, SPLEN20179810, SPLEN20186430,
STOMA20001830, STOMA20005390, STOMA20005670, STOMA20006400,
STOMA20008880, STOMA20034770, STOMA20056640, STOMA20056670,
STOMA20083610, STOMA20088380, STOMA20092530, SYNOV20001520,
SYNOV20001730, SYNOV20002510, SYNOV20002790, SYNOV20002970,
SYNOV20004260, SYNOV20007000, SYNOV20008240, SYNOV20009230,
SYNOV20010880, SYNOV20011110, SYNOV20013000, SYNOV20013560,
SYNOV20013900, TESOP20004000, TESTI20136100, TESTI20216370,
TESTI20244190, TESTI20254860, TESTI20303220, TESTI20335200,
TESTI20352620, TESTI20358980, TESTI20442760, TESTI20449200,
TESTI20455090, THYMU10005360, THYMU10005540, THYMU20147770,
THYMU20159430, THYMU20241850, TRACH20016210, TRACH20050040,
TRACH20067620, TRACH20069180, TRACH20076740, TRACH20128230,
UTERU20046980, UTERU20064860, UTERU20144640, UTERU20158800,
UTERU20161570, UTERU20183640
[0093] The following 84 clones presumably belong to signal
transduction-related proteins.
[0094] ASTRO20108190, BRACE20115920, BRACE20154120, BRACE20177200,
BRACE20237270, BRAMY20104640, BRAMY20242470, BRAMY20271400,
BRAWH20016620, BRAWH20103290, BRAWH20149340, BRCOC20021550,
BRCOC20091960, BRHIP20189980, BRHIP20218580, BRHIP20238600,
BRSSN20038200, CD34C30004240, CTONG20118150, CTONG20127450,
CTONG20200310, FCBBF30012350, FCBBF40001730, FEBRA10001880,
FEBRA20004620, FEBRA20132740, FEBRA20144170, FEHRT20003250,
HCHON20007510, HLUNG20033780, IMR3220002430, KIDNE20008010,
KIDNE20102710, KIDNE20107620, NT2NE20080170, NT2NE20181650,
NT2RP70027380, NT2RP70036880, NT2RP70063950, NT2RP70078420,
NT2RP70159960, NTONG20046140, NTONG20056570, OCBBF20028050,
OCBBF20053430, OCBBF20054760, OCBBF20124360, OCBBF20127140,
OCBBF20149280, OCBBF20173980, PEBLM20013120, PEBLM20085760,
PROST20161950, PUAEN20015260, PUAEN20015860, PUAEN20083140,
SMINT20028820, SMINT20049090, SMINT20110660, SPLEN20011410,
SPLEN20121750, SPLEN20170310, SPLEN20181810, SPLEN20222270,
SPLEN20250170, SPLEN20283650, TESTI20035960, TESTI20288910,
TESTI20305540, TESTI20326810, TESTI20369650, TESTI20392250,
TESTI20416640, TESTI20432750, TESTI20467320, THYMU20169680,
THYMU20172150, THYMU20201980, THYMU20202890, TKIDN20004640,
TKIDN20047480, TRACH20057690, UMVEN10001860, UTERU20146310
[0095] The following 144 clones presumably belong to
transcription-related proteins.
[0096] 3NB6920014590, ADIPS20004250, ASTRO20008010, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20060890, BRACE20068590,
BRACE20257100, BRAMY20210400, BRAMY20260910, BRAMY20270730,
BRAWH20028110, BRAWH20075700, BRAWH20096780, BRCAN20280210,
BRCOC20144000, BRCOC20178270, BRHIP20005340, BRHIP20096170,
BRHIP20119330, BRHIP20191860, BRHIP20195890, BRHIP20222280,
BRSSN20039370, BRSSN20046790, BRSSN20176820, CTONG20050280,
CTONG20075860, CTONG20085950, CTONG20091080, CTONG20092700,
CTONG20121010, CTONG20124220, CTONG20133390, CTONG20133520,
D9OST20033970, FCBBF10001710, FCBBF10004370, FCBBF20059090,
FCBBF20068820, FCBBF30007680, FCBBF30010810, FCBBF30018550,
FCBBF30025560, FCBBF30057290, FCBBF30083820, FCBBF30129630,
FCBBF30240960, FCBBF30246230, FEBRA20018690, FEBRA20026110,
FEBRA20034680, FEBRA20040530, FEBRA20082010, FEBRA20171380,
FEBRA20195820, FEBRA20233770, HCHON20008320, HCHON20009560,
HCHON20035130, HHDPC10000830, HHDPC20030490, HHDPC20031130,
KIDNE20027250, KIDNE20027950, KIDNE20182690, LIVER20055440,
NT2NE20010490, NT2NE20089970, NT2NE20142210, NT2NE20184900,
NT2RP60000770, NT2RP70043480, NT2RP70063950, NT2RP70102350,
NT2RP70157890, NTONG20070200, OCBBF10001850, OCBBF20020830,
OCBBF20037440, OCBBF20046120, OCBBF20049300, OCBBF20054200,
OCBBF20066390, OCBBF20071840, OCBBF20080410, OCBBF20108190,
OCBBF20125530, OCBBF20148280, PEBLM20060360, PEBLM20078320,
PERIC20003870, PROST10003220, PROST20047390, PROST20066880,
PROST20185830, PROST20189770, PROST20191640, SKNSH20008190,
SMINT20001760, SMINT20028820, SMINT20130320, SMINT20144800,
SPLEN20026950, SPLEN20054290, SPLEN20079260, SPLEN20095410,
SPLEN20117660, SPLEN20140800, SPLEN20147390, SPLEN20160450,
SPLEN20162680, SPLEN20243830, SPLEN20250170, SPLEN20252190,
SPLEN20267650, STOMA20032890, STOMA20063250, TESTI20039400,
TESTI20041690, TESTI20067200, TESTI20088220, TESTI20130010,
TESTI20156100, TESTI20230850, TESTI20318090, TESTI20320670,
TESTI20378190, TESTI20385960, TESTI20409890, TESTI20420620,
TESTI20432820, TESTI20456110, THYMU20247480, TRACH20079690,
TRACH20154860, TRACH20163170, TRACH20164980, TRACH20184490,
UTERU20099720, UTERU20116570, UTERU20145480, UTERU20176130
[0097] The following 387 clones presumably belong to
disease-related proteins.
[0098] ADIPS20004250, ADRGL10001470, ADRGL20011190, ADRGL20018300,
ADRGL20035850, ADRGL20078100, ASTRO10001650, ASTRO20008010,
ASTRO20027430, ASTRO20106150, ASTRO20108190, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20038480, BRACE20039540,
BRACE20059370, BRACE20108130, BRACE20108880, BRACE20115920,
BRACE20116460, BRACE20232840, BRACE20248260, BRACE20253330,
BRACE20284100, BRALZ20013500, BRALZ20017430, BRALZ20018340,
BRAMY20000520, BRAMY20025840, BRAMY20120910, BRAMY20134140,
BRAMY20135900, BRAMY20162510, BRAMY20174550, BRAMY20210400,
BRAMY20211390, BRAMY20242470, BRAMY20245300, BRAMY20266850,
BRAMY20285160, BRAWH20016620, BRAWH20028110, BRAWH20064050,
BRAWH20096780, BRAWH20110960, BRAWH20113430, BRAWH20114000,
BRAWH20118230, BRAWH20121640, BRAWH20128270, BRAWH20137480,
BRCAN20103740, BRCAN20224720, BRCAN20279700, BRCAN20280210,
BRCAN20283190, BRCOC20001860, BRCOC20006370, BRCOC20027510,
BRCOC20055420, BRCOC20099370, BRCOC20178270, BRCOC20178560,
BRHIP20003120, BRHIP20005340, BRHIP20174040, BRHIP20176420,
BRHIP20191490, BRHIP20191860, BRHIP20194940, BRHIP20195890,
BRHIP20222280, BRHIP20249110, BRHIP20285930, BRHIP30004880,
BRSSN20013420, BRSSN20038200, BRSSN20039370, BRSSN20046790,
BRSSN20066110, BRSSN20101100, BRSSN20120810, BRSSN20187310,
BRTHA20046290, CD34C30004240, COLON10001350, CTONG20004690,
CTONG20052650, CTONG20099550, CTONG20124220, CTONG20125640,
CTONG20128430, CTONG20131560, CTONG20133390, CTONG20153300,
CTONG20153580, CTONG20158040, CTONG20159530, D6OST20003580,
D9OST20023970, DFNES20001530, DFNES20037420, FCBBF10001210,
FCBBF10001710, FCBBF10003770, FCBBF20059090, FCBBF20064520,
FCBBF20068820, FCBBF30010810, FCBBF30024750, FCBBF30025560,
FCBBF30039020, FCBBF30049550, FCBBF30057290, FCBBF30083620,
FCBBF30129630, FCBBF30190850, FCBBF30238870, FCBBF30240960,
FCBBF30243640, FCBBF30279030, FCBBF30281880, FCBBF40001730,
FEBRA10001880, FEBRA20004620, FEBRA20010120, FEBRA20018690,
FEBRA20082010, FEBRA20097310, FEBRA20130190, FEBRA20132740,
FEBRA20144170, FEBRA20195820, FEBRA20223220, FEBRA20233770,
FEBRA20235500, FEHRT20003250, HCHON10001760, HCHON20007380,
HCHON20008320, HCHON20009560, HCHON20015230, HCHON20015980,
HCHON20016040, HCHON20035130, HCHON20036420, HCHON20064590,
HCHON20067700, HCHON20086720, HCHON20100740, HEART20003060,
HEART20017730, HEART20025980, HEART20049410, HHDPC20014320,
HHDPC20030490, HHDPC20084140, HHDPC20091140, HHDPC20091780,
HHDPC20092080, HLUNG20033780, IMR3220002430, KIDNE20007770,
KIDNE20020150, KIDNE20021680, KIDNE20022620, KIDNE20024830,
KIDNE20027950, KIDNE20101370, KIDNE20101510, KIDNE20182690,
LIVER20002160, LIVER20055200, LIVER20055440, LIVER20059810,
LIVER20064690, MESAN20101140, MESAN20125860, MESAN20130220,
MESAN20154010, MESAN20174170, NOVAR10000910, NT2NE20010490,
NT2NE20118960, NT2NE20157470, NT2RI20040990, NT2RI20041880,
NT2RI20048840, NT2RI20050960, NT2RI20240080, NT2RP60000770,
NT2RP70027380, NT2RP70032610, NT2RP70037240, NT2RP70192730,
NT2RP70198350, NTONG20013620, NTONG20015870, NTONG20028070,
NTONG20067830, NTONG20070200, NTONG20090600, NTONG20092330,
OCBBF20006770, OCBBF2003744.0, OCBBF20046120, OCBBF20049300,
OCBBF20053490, OCBBF20053730, OCBBF20054760, OCBBF20071840,
OCBBF20072240, OCBBF20078920, OCBBF20108430, OCBBF20108580,
OCBBF20127140, OCBBF20129360, OCBBF20145760, OCBBF20153350,
OCBBF20173980, OCBBF20178880, PEBLM10000710, PEBLM20013120,
PERIC10000250, PLACE60060420, PLACE60177140, PROST20100460,
PROST20159240, PROST20169800, PROST20176170, PUAEN20018820,
PUAEN20030180, PUAEN20055020, PUAEN20083140, SKMUS20018230,
SKMUS20018500, SKMUS20021530, SKMUS20024750, SKMUS20029200,
SKMUS20048970, SKMUS20049030, SKNSH20008190, SKNSH20089400,
SMINT20001760, SMINT20026890, SMINT20028820, SMINT20050750,
SMINT20073650, SMINT20105330, SMINT20112730, SMINT20121220,
SMINT20127350, SMINT20127930, SMINT20136130, SMINT20138900,
SMINT20153260, SMINT20155180, SMINT20179740, SMINT20190170,
SMINT20191420, SPLEN20006070, SPLEN20011410, SPLEN20026950,
SPLEN20027440, SPLEN20039240, SPLEN20079260, SPLEN20095410,
SPLEN20146450, SPLEN20147390, SPLEN20151210, SPLEN20160450,
SPLEN20170310, SPLEN20179180, SPLEN20186430, SPLEN20212730,
SPLEN20243830, SPLEN20245300, SPLEN20250390, SPLEN20252190,
SPLEN20267650, SPLEN20305620, STOMA20001830, STOMA20005390,
STOMA20008880, STOMA20010250, STOMA20034770, STOMA20046680,
STOMA20056670, STOMA20064470, STOMA20077450, STOMA20080500,
STOMA20083610, STOMA20088380, SYNOV20001520, SYNOV20001730,
SYNOV20002790, SYNOV20002970, SYNOV20007000, SYNOV20008240,
SYNOV20009230, SYNOV20010880, SYNOV20011110, TBAES20003770,
TESOP20004000, TESOP20005270, TESTI20031270, TESTI20036380,
TESTI20044310, TESTI20067200, TESTI20116830, TESTI20121550,
TESTI20156100, TESTI20168480, TESTI20208400, TESTI20215990,
TESTI20231940, TESTI20234360, TESTI20237520, TESTI20238610,
TESTI20239510, TESTI20249990, TESTI20266740, TESTI20316870,
TESTI20318090, TESTI20335050, TESTI20335200, TESTI20343570,
TESTI20352620, TESTI20368330, TESTI20369650, TESTI20385960,
TESTI20392250, TESTI20400940, TESTI20404240, TESTI20420620,
TESTI20436560, TESTI20438570, TESTI20441940, TESTI20442760,
TESTI20443090, TESTI20449200, TESTI20455090, TESTI20455620,
TESTI20456110, TESTI20463580, TESTI20465350, TESTI20465690,
TESTI20467210, THYMU20122730, THYMU20126900, THYMU20130890,
THYMU20159430, THYMU20169680, THYMU20172150, THYMU20180280,
THYMU20193640, THYMU20209590, THYMU20232090, THYMU20247480,
TKIDN10000010, TKIDN20004640, TKIDN20047480, TRACH20016210,
TRACH20019960, TRACH20050040, TRACH20057690, TRACH20067620,
TRACH20077540, TRACH20079690, TRACH20096610, TRACH20105870,
TRACH20121380, TRACH20154860, TRACH20162860, TRACH20163170,
TRACH20164980, TRACH20190240, TSTOM20005690, TUTER20002830,
UTERU20030570, UTERU20116570, UTERU20144640, UTERU20151980,
UTERU20158800, UTERU20183640, UTERU20185230
[0099] The following 206 clones presumably belong to the category
of enzymes and/or metabolism-related proteins.
[0100] 3NB6910001910, ADRGL10001470, ADRGL20035850, ADRGL20078100,
ASTRO20105820, ASTRO20106150, ASTRO20130500, ASTRO20145760,
BRACE20027620, BRACE20038000, BRACE20062640, BRACE20096200,
BRACE20107530, BRACE20108130, BRACE20108880, BRACE20116460,
BRACE20148240, BRACE20185680, BRACE20253160, BRALZ20017430,
BRALZ20018340, BRAMY20104640, BRAMY20134140, BRAMY20153110,
BRAMY20213100, BRAMY20252720, BRAWH20016620, BRAWH20105840,
BRAWH20112940, BRAWH20114000, BRAWH20117950, BRAWH20125380,
BRAWH20132190, BRAWH20171030, BRCAN20054490, BRCAN20224720,
BRCAN20280360, BRCAN20283190, BRCAN20283380, BRCOC20001860,
BRCOC20031250, BRCOC20055420, BRCOC20091960, BRCOC20144000,
BRHIP10001290, BRHIP20005530, BRHIP20096850, BRHIP20103090,
BRHIP20174040, BRHIP20249110, BRSSN20013420, BRSSN20015790,
BRSSN20120810, BRSSN20146100, CTONG20095340, CTONG20106520,
CTONG20118250, CTONG20127450, CTONG20140580, CTONG20153300,
CTONG20158040, D3OST20006180, D6OST20003580, DFNES20031920,
DFNES20071130, FCBBF10001820, FCBBF10003670, FCBBF30012350,
FCBBF30012810, FCBBF30175310, FCBBF30243640, FEBRA10001880,
FEBRA20007620, FEBRA20130190, FEBRA20144170, FEBRA20167390,
FEBRA20196630, FEHRT20003250, HCHON10001760, HCHON20003220,
HCHON20015350, HEART20034320, HEART20090000, HHDPC20014320;
KIDNE20002520, KIDNE20008010, KIDNE20021680, KIDNE20022620,
KIDNE20028390, KIDNE20028720, KIDNE20107620, LIVER20059810,
MESAN20154010, NT2NE20118960, NT2NE20157470, NT2RI20005750,
NT2RI20244600, NT2RI20273230, NT2RP70032610, NT2RP70045590,
NT2RP70192730, NT2RP70195430, NTONG20009770, NTONG20013620,
NTONG20046140, OCBBF20028650, OCBBF20030910, OCBBF20046690,
OCBBF20050770, OCBBF20053430, OCBBF20053490, OCBBF20053730,
OCBBF20054760, OCBBF20078920, OCBBF20124360, OCBBF20129360,
OCBBF20178880, PEBLM20044520, PEBLM20052820, PEBLM20060490,
PERIC10000250, PLACE50000660, PROST20083600, PROST20169800,
PUAEN20015260, PUAEN20030180, SKMUS20018230, SMINT20028820,
SMINT20049090, SMINT20102780, SMINT20105330, SMINT20106290,
SMINT20110660, SMINT20152940, SMINT20191420, SMINT20191530,
SPLEN20021660, SPLEN20026950, SPLEN20121750, SPLEN20145720,
SPLEN20149240, SPLEN20150940, SPLEN20151210, SPLEN20173510,
SPLEN20212730, SPLEN20250390, SPLEN20305620, STOMA20006860,
STOMA20077450, TBAES20002550, TBAES20003150, TESOP20004000,
TESOP20005270, TESTI20001000, TESTI20002720, TESTI20002780,
TESTI20060400, TESTI20066670, TESTI20082330, TESTI20083200,
TESTI20108720, TESTI20116830, TESTI20143390, TESTI20148000,
TESTI20216370, TESTI20232140, TESTI20234360, TESTI20237520,
TESTI20239510, TESTI20266740, TESTI20314180, TESTI20334410,
TESTI20343570, TESTI20352620, TESTI20355020, TESTI20366910,
TESTI20368330, TESTI20369650, TESTI20375340, TESTI20397760,
TESTI20416640, TESTI20432750, TESTI20463580, TESTI20465350,
TESTI20471410, TESTI20473830, THYMU20023380, THYMU20111830,
THYMU20126900, THYMU20169680, THYMU20202890, TKIDN20004640,
TKIDN20047480, TRACH20003590, TRACH20016210, TRACH20019960,
TRACH20041830, TRACH20057690, TRACH20067620, TRACH20084720,
TRACH20085830, TRACH20162860, UTERU20064860, UTERU20144640,
UTERU20146310, UTERU20151980
[0101] The following 33 clones presumably belong to the category of
cell division- and/or cell proliferation-related proteins.
[0102] BRALZ20077900, BRAMY20135900, BRAWH20002320, BRAWH20128270,
BRCAN20071190, BRCAN20273640, BRHIP20096170, CTONG10000940,
CTONG20124220, FCBBF30247930, FEBRA20113560, HCASM10000500,
HCHON20097490, MESAN20025190, NT2RI20050960, OCBBF20039250,
OCBBF20054760, OCBBF20072240, SMINT20051610, SPLEN20147110,
SPLEN20284240, TESOP20005690, TESTI20234360, TESTI20305540,
TESTI20332420, TESTI20335050, TESTI20368330, TESTI20392760,
TESTI20400940, THYMU20161640, TKIDN20047480, UTERU20097760,
UTERU20185230
[0103] The following 75 clones presumably belong to the category of
cytoskeleton-related proteins.
[0104] ADRGL20011190, ADRGL20018300, ASTRO10001650, ASTRO20055750,
BRACE20003070, BRACE20059370, BRACE20163350, BRAMY20121620,
BRAMY20157820, BRAMY20242470, BRAWH20028110, BRAWH20137480,
BRCAN20003460, BRCOC20008160, BRCOC20059510, BRHIP20115080,
BRHIP20137230, BRHIP20167880, BRHIP20283030, BRHIP20285830,
BRSSN20187310, CTONG10002770, CTONG20052900, CTONG20121580,
FCBBF10001150, FCBBF30013770, FCBBF30015940, FCBBF30049550,
FEBRA20024100, FEBRA20237640, HCHON20015980, HCHON20068410,
HEART20017730, HEART20025980, HEART20061950, HEART20077670,
HLUNG20016330, KIDNE20118580, MESAN20004570, NT2RI20040990,
NT2RI20041880, NT2RP70037240, NT2RP70062230, NTONG20015870,
NTONG20056570, NTONG20067830, NTONG20090600, OCBBF20107090,
OCBBF20155060, PLACE60079250, PUAEN20040670, SKMUS20001980,
SKMUS20016220, SKMUS20048970, SKMUS20049030, SMINT20024570,
SMINT20026890, SMINT20121220, SMINT20138900, SPLEN20006070,
SPLEN20027440, SPLEN20142100, TESTI20063830, TESTI20094230,
TESTI20278400, TESTI20371030, TESTI20417300, TESTI20436560,
TESTI20455090, THYMU20105190, THYMU20172150, THYMU20209590,
TRACH20096610, UMVEN10001560, UTERU20116570
[0105] The following 65 clones presumably belong to the category of
nuclear proteins and/or RNA synthesis-related proteins.
[0106] BRACE20057190, BRACE20064880, BRACE20248260, BRACE20253160,
BRAMY20000520, BRAMY20120910, BRAWH20113430, BRAWH20171030,
BRCAN10001490, BRCAN20283190, BRCOC20037320, BRCOC20178560,
BRHIP20106100, BRHIP20176420, BRHIP20243470, BRSSN20101100,
CTONG20114290, CTONG20125540, CTONG20131560, CTONG20140580,
DFNES20001530, FCBBF20064520, FEBRA20007620, FEBRA20010120,
FEBRA20097310, FEBRA20144170, FEBRA20174410, FEBRA20215500,
IMR3220002430, MESAN20101140, NT2RI20273230, OCBBF20028650,
OCBBF20030910, OCBBF20078920, PROST20104000, PUAEN20018820,
SKMUS20007010, SMINT20127350, SMINT20177360, SMINT20191530,
SPLEN20008740, SPLEN20146450, STOMA20046680, TESTI20082330,
TESTI20094470, TESTI20121550, TESTI20208400, TESTI20234360,
TESTI20237520, TESTI20249990, TESTI20334410, TESTI20355020,
TESTI20368330, TESTI20392760, TESTI20408970, TESTI20436560,
TESTI20438570, TESTI20443090, THYMU20193640, THYMU20202890,
THYMU20241210, TRACH20096610, TUTER20002830, UTERU20151980,
UTERU20176320
[0107] The following 62 clones presumably belong to the category of
protein synthesis- and/or protein transport-related proteins.
[0108] 3NB6910001910, ASTRO20106150, ASTRO20130500, ASTRO20141350,
BRACE20038480, BRACE20052160, BRACE20057620, BRACE20106840,
BRACE20172980, BRACE20192440, BRAWH20110960, BRCOC20037320,
BRHIP20005530, BRSSN20120810, BRSTN20005360, CTONG20009770,
CTONG20114290, CTONG20125640, CTONG20153300, D6OST20003580,
DFNES20037420, FCBBF30012810, FEBRA20080810, HCHON20064590,
HHDPC20014320, HHDPC20084140, HLUNG20017120, LIVER20064690,
NT2NE20132170, NT2NE20157470, NT2RP70133740, NTONG20009770,
NTONG20075220, NTONG20076930, OCBBF20030910, OCBBF20035930,
OCBBF20153340, PLACE60060420, SMINT20152940, SPLEN20008740,
SPLEN20103950, SPLEN20118300, SPLEN20212730, SPLEN20250390,
STOMA20077450, TBAES20002550, TESOP20004000, TESTI20239510,
TESTI20278400, TESTI20314180, TESTI20463580, THYMU20111830,
THYMU20122730, THYMU20130890, THYMU20232090, TKIDN10000010,
TRACH20084720, TRACH20105870, TRACH20139820, TRACH20149970,
UTERU20120310, UTERU20188110
[0109] The following 15 clones presumably belong to the category of
cellular defense-related proteins.
BRCOC20144000, CTONG20092680, KIDNE20020150, LIVER20002160,
NT2RI20050960, NT2RP70045590, OCBBF20128120, PLACE60003480,
SKNSH20089400, SMINT20106290, SPLEN20039240, TESTI20001000,
TESTI20455620, TRACH20028030, UTERU20176320
[0110] The following 13 clones presumably belong to the category of
development and/or differentiation-related proteins.
3NB6920014590, BRAMY20211390, CTONG20091080, CTONG20121010,
FCBBF30024750, KIDNE20027250, NT2NE20142210, OCBBF20054200,
PROST10003220, SKMUS20007010, SPLEN20179810, STOMA20063250,
TESTI20291960
[0111] The following 174 clones presumably belong to the category
of DNA- and/or RNA-binding proteins.
[0112] 3NB6920014590, ADIPS20004250, ASTRO20008010, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20057620, BRACE20060890,
BRACE20064880, BRACE20068590, BRACE20248260, BRACE20253160,
BRAMY20000520, BRAMY20213100, BRAMY20260910, BRAMY20270730,
BRAWH20028110, BRAWH20075700, BRAWH20096780, BRAWH20113430,
BRCAN10001490, BRCAN20280210, BRCAN20283190, BRCOC20144000,
BRCOC20178270, BRCOC20178560, BRHIP20005340, BRHIP20106100,
BRHIP20119330, BRHIP20153600, BRHIP20176420, BRHIP20191860,
BRHIP20195890, BRHIP20222280, BRSSN20039370, BRSSN20046790,
BRSSN20176820, CTONG20050280, CTONG20075860, CTONG20085950,
CTONG20091080, CTONG20092700, CTONG20121010, CTONG20124220,
CTONG20125540, CTONG20133390, CTONG20133520, CTONG20140580,
CTONG20156780, D9OST20033970, FCBBF10001710, FCBBF10004370,
FCBBF20059090, FCBBF20064520, FCBBF20068820, FCBBF30007680,
FCBBF30010810, FCBBF30018550, FCBBF30025560, FCBBF30057290,
FCBBF30083820, FCBBF30129630, FCBBF30240960, FCBBF30246230,
FEBRA20010120, FEBRA20018690, FEBRA20026110, FEBRA20034680,
FEBRA20040530, FEBRA20082010, FEBRA20097310, FEBRA20171380,
FEBRA20195820, FEBRA20196630, FEBRA20233770, HCHON20008320,
HCHON20009560, HCHON20035130, HHDPC10000830, HHDPC20031130,
KIDNE20017130, KIDNE20027250, KIDNE20027950, KIDNE20107390,
KIDNE20182690, LIVER20055440, MESAN20101140, NT2NE20010490,
NT2NE20089970, NT2NE20142210, NT2NE20184900, NT2RP60000770,
NT2RP70044280, NT2RP70102350, NT2RP70157890, NTONG20070200,
OCBBF10001850, OCBBF20020830, OCBBF20037440, OCBBF20046120,
OCBBF20049300, OCBBF20066390, OCBBF20071840, OCBBF20078920,
OCBBF20080410, OCBBF20108190, OCBBF20125530, OCBBF20148280,
PEBLM20060360, PEBLM20060490, PEBLM20078320, PERIC10000250,
PROST10003220, PROST20047390, PROST20066880, PROST20185830,
PROST20189770, PROST20191640, PUAEN20018820, SKNSH20008190,
SKNSH20089400, SMINT20001760, SMINT20127350, SMINT20144800,
SMINT20177360, SMINT20191530, SPLEN20054290, SPLEN20079260,
SPLEN20095410, SPLEN20140800, SPLEN20147390, SPLEN20160450,
SPLEN20252190, SPLEN20267650, STOMA20010250, STOMA20032890,
STOMA20046680, STOMA20063250, TESTI20039400, TESTI20067200,
TESTI20088220, TESTI20094470, TESTI20121550, TESTI20130010,
TESTI20156100, TESTI20204450, TESTI20230850, TESTI20237520,
TESTI20266740, TESTI20318090, TESTI20320670, TESTI20334410,
TESTI20355020, TESTI20378190, TESTI20385960, TESTI20432820,
TESTI20443090, TESTI20456110, THYMU20193640, THYMU20241210,
THYMU20247480, TRACH20079690, TRACH20105870, TRACH20139820,
TRACH20154860, TRACH20163170, TRACH20164980, TRACH20184490,
TUTER20002830, UTERU20099720, UTERU20116570, UTERU20145480,
UTERU20176130, UTERU20185230
[0113] The following 68 clones presumably belong to the category of
ATP- and/or GTP-binding proteins.
[0114] 3NB6910001910, BRACE20108130, BRACE20148240, BRAMY20134140,
BRAMY20157820, BRAMY20174550, BRAWH20164460, BRCAN20003460,
BRCAN20054490, BRCAN20283190, BRCOC20059510, BRCOC20144000,
BRHIP20103090, BRHIP20115080, BRHIP20167880, BRSTN20005360,
CD34C30004240, CTONG20095340, CTONG20121580, CTONG20200310,
DFNES20037420, FCBBF20067810, FCBBF30012350, FCBBF30015940,
FEBRA20007620, FEBRA20024100, FEBRA20144170, KIDNE20020150,
KIDNE20028720, LIVER20002160, LIVER20087060, NT2RI20005750,
NT2RI20041880, NT2RI20048840, NT2RI20273230, OCBBF20028650,
OCBBF20046690, OCBBF20054760, OCBBF20108430, OCBBF20108630,
SMINT20121220, SMINT20183530, SMINT20191530, SPLEN20026950,
SPLEN20039240, SPLEN20099700, SPLEN20145720, SPLEN20179180,
STOMA20006860, TESTI20035960, TESTI20355020, TESTI20397760,
TESTI20400940, TESTI20417300, TESTI20443090, TESTI20455620,
THYMU20105190, THYMU20202890, THYMU20209590, TKIDN20004640,
TKIDN20047480, TRACH20005400, TRACH20019960, TRACH20057690,
TRACH20084720, UTERU20168220, UTERU20176320, UTERU20185230
[0115] Among the clones other than the ones shown above,
BRAMY20248490, FCBBF10002800, NTONG20092290, OCBBF20127040,
SMINT20163960, THYMU20279750, TRACH20167220, are clones which were
predicted to highly possibly belong to the category of secretory
protein and/or membrane protein based on the result of domain
search by Pfam.
FCBBF10002800, NTONG20092290, OCBBF20127040, SMINT20163960,
TESTI20478850, THYMU20279750
[0116] The 6 clones shown above are clones which were predicted to
highly possibly belong to the category of glycoprotein-related
protein based on the result of domain search by Pfam.
BRACE20060720, BRACE20223330, BRALZ20058880, BRAMY20148130,
BRAWH20101360, BRCAN20124080, BRHIP20253660, CTONG10000620,
CTONG20014280, CTONG20124010, KIDNE20109890, MESAN20171520,
OCBBF20109310, OCBBF20140640, PROST20079500, PUAEN20078980,
SPLEN20077500, SPLEN20143180, TESTI20017950, TESTI20184620,
TESTI20208710, TESTI20211160, TESTI20226230, TESTI20234140,
TESTI20258460, TESTI20275030
[0117] The 26 clones shown above are clones which were predicted to
highly possibly belong to the category of signal
transduction-related protein based on the result of domain search
by Pfam.
[0118] ADRGL20048330, ASTRO20064750, ASTRO20084250, BRACE20151320,
BRALZ20058880, BRHIP20207990, CTONG20093950, FCBBF30195640,
FEBRA10001900, FEBRA20090290, FEBRA20214970, FEBRA20222040,
KIDNE20109890, LIVER20087510, MESAN20029400, MESAN20031900,
MESAN20035290, MESAN20136110, NT2NE20130190, PEBLM20060310,
PERIC20004780, PROST20171280, PUAEN20078980, SMINT20115880,
SPLEN20095550, TESTI20023510, TESTI20083940, TESTI20152460,
TESTI20185650, TESTI20189410, TESTI20200710, TESTI20308600,
TESTI20343070, TESTI20369690, TESTI20381040, UTERU20050690
[0119] The 36 clones shown above are clones which were predicted to
highly possibly belong to the category of transcription-related
protein based on the result of domain search by Pfam.
BGGI120006160, BRACE20053480, BRACE20190040, BRACE20223330,
BRAWH20101360, BRAWH20185060, BRCOC20023230, BRHIP20252450,
BRSSN20105870, BRSSN20117990, BRTHA20000570, CTONG20098440,
CTONG20129960, CTONG20146300, CTONG20155180, FEBRA20025270,
HEART20083640, KIDNE20009470, LIVER20035680, MESAN20029400,
MESAN20031900, MESAN20186700, NOVAR10000150, NTONG20029480,
OCBBF20079310, OCBBF20082830, PEBLM20042900, PLACE60136500,
PLACE60136720, PROST20114390, SKNSH20020540, SMINT20013480,
SMINT20174360, SPLEN20077500, SPLEN20119810, SPLEN20126190,
SPLEN20174260, SPLEN20211220, TESTI20046750, TESTI20057750,
TESTI20061110, TESTI20197940, TESTI20211160, TESTI20226230,
TESTI20255820, TESTI20317600, TESTI20377230, THYMU20111180,
THYMU20115850, THYMU20143270, THYMU20240710, UTERU20055330,
UTERU20055930, UTERU20064000, UTERU20119060
[0120] The 55 clones shown above are clones which were predicted to
highly possibly belong to the category of enzyme and/or
metabolism-related protein based on the result of domain search by
Pfam.
TESTI20127760, TESTI20392270
[0121] The 2 clone shown above is a clone which was predicted to
highly possibly belong to the category of cell division and/or cell
proliferation-related protein based on the result of domain search
by Pfam.
FCBBF30262510, MESAN20031900, NT2NE20125050, SMINT20068010,
SPLEN20163560, STOMA20092890, TESTI20382750
[0122] The 7 clones shown above are clones which were predicted to
highly possibly belong to the category of cytoskeleton-related
protein based on the result of domain search by Pfam.
THYMU20118520
[0123] The clone shown above is clone which was predicted to highly
possibly belong to the category of Nuclear protein and/or RNA
synthesis-related protein based on the result of domain search by
Pfam.
BRACE20053480, BRACE20240740, KIDNE20009470, OCBBF20140890,
SMINT20035690, UTERU20064000
[0124] The 6 clones shown above are clones which were predicted to
highly possibly belong to the category of Protein synthesis-and/or
transport-related protein based on the result of domain search by
Pfam.
[0125] ADRGL20048330, ASTRO20064750, ASTRO20084250, BRACE20151320,
BRACE20190040, BRACE20223330, BRALZ20058880, BRAMY20103570,
BRCOC20023230, BRHIP20207990, BRTHA20000570, CTONG20093950,
CTONG20129960, CTONG20146300, CTONG20155180, CTONG20160560,
FCBBF10004120, FCBBF30195640, FEBRA10001900, FEBRA20090290,
FEBRA20214970, FEBRA20222040, HCHON20008150, HEART20083640,
KIDNE20109890, LIVER20035680, LIVER20087510, MESAN20029400,
MESAN20031900, MESAN20035290, MESAN20136110, MESAN20186700,
NT2NE20130190, NT2RI20025640, NTONG20029480, PEBLM20060310,
PERIC20004780, PROST20114390, PROST20171280, PUAEN20078980,
SMINT20115880, SPLEN20095550, SPLEN20119810, TESTI20023510,
TESTI20057750, TESTI20083940, TESTI20152460, TESTI20185650,
TESTI20189410, TESTI20200710, TESTI20308600, TESTI20343070,
TESTI20369690, TESTI20381040, THYMU20115850, UTERU20050690,
UTERU20055330
[0126] The 57 clones shown above are clones which were predicted to
highly possibly belong to the category of DNA- and/or RNA-binding
protein based on the result of domain search by Pfam.
PLACE60136720
[0127] The clone shown above is a clone which was predicted to
highly possibly belong to the category of ATP- and/or GTP-binding
proteins based on the result of domain search by Pfam.
[0128] The 213 clones shown below are clones which were
unassignable to any of the above-mentioned categories, but have
been predicted to have some functions based on homology search
using their full-length nucleotide sequences and motif search in
their estimated ORFs. Clone Name, Definition in the result of
homology search or Motif Name in the motif search, demarcated by a
double slash mark (//), are shown below.
ADRGL20028570//Rattus norvegicus MG87 mRNA, complete cds.
ADRGL20061930//transposon-derived Buster1 transposase-like
protein
ASTRO20012490//Eukaryotic initiation factor 1A
ASTRO20072210//PERIAXIN.
ASTRO20114370//Mus musculus SMAR1 mRNA, complete cds.
ASTRO20125520//dnaj protein [Schizosaccharomyces pombe]
ASTRO20143630//KH domain// Bacterial regulatory proteins, crp
family
ASTRO20155290//TPR Domain// TPR Domain// TPR Domain
ASTRO20181690//oocyte-specific protein P100
BGGI110001930//UBX domain
BRACE20011070//Mus musculus F-box protein FBX15 mRNA, partial
cds.
BRACE20039440//Drosophila melanogaster CHARYBDE (charybde) mRNA,
complete cds.
BRACE20050900//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
BRACE20053280//Mus musculus Pdz-containing protein (Pdzx) mRNA,
complete cds.
BRACE20057730//toxin sensitivity protein KTI12 homolog
BRACE20058580//Homo sapiens HCMOGT-1 mRNA for sperm antigen,
complete cds.
BRACE20063780//NOL1/NOP2/sun family
BRACE20269200//Heat-labile enterotoxin alpha chain
BRACE20276430//Homo sapiens retinoblastoma-associated protein
RAP140 mRNA, complete cds.
BRACE20286360//Alpha adaptin carboxyl-terminal domain
BRAMY10001300//Homo sapiens MAGE-E1b mRNA, complete cds.
BRAMY20045240//Flagellar L-ring protein
BRAMY20054880//Rattus norvegicus KPL2 (Kp12) mRNA, complete
cds.
BRAMY20167060//Collagen triple helix repeat (20 copies)
BRAMY20184670//Homo sapiens mRNA for ALEX1, complete cds.
BRAMY20217460//Homo sapiens cardiac voltage gated potassium channel
modulatory subunit mRNA, complete cds, alternatively spliced.
BRAMY20240040//Homo sapiens suppressor of white apricot homolog 2
(SWAP2) mRNA, complete cds.
BRAMY20247110//Mus musculus semaphorin cytoplasmic
domain-associated protein 3A (Semcap3) mRNA, complete cds.
BRAWH20004600//Mus musculus mRNA for NAKAP95, complete cds.
BRAWH20011710//cytoplasmic linker 2
BRAWH20012390//Trichomonas vaginalis mRNA for centrin (ce1
gene).
BRAWH20017010//Homo sapiens testes development-related NYD-SP22
mRNA, complete cds.
BRAWH20029630//Homo sapiens bet3 (BET3) mRNA, complete cds.
BRAWH20138660//Homo sapiens stonin 2 mRNA, complete cds.
BRCOC20008500//Human ras inhibitor mRNA, 3' end.
BRCOC20026640//Gag P30 core shell protein
BRCOC20035130//14-3-3 PROTEIN EPSILON (MITOCHONDRIAL IMPORT
STIMULATION FACTOR L SUBUNIT) (PROTEIN KINASE C INHIBITOR
PROTEIN-1) (KCIP-1) (14-3-3E).
BRCOC20074760//CDC4-LIKE PROTEIN (FRAGMENT).
BRCOC20110100//Integrase core domain
BRCOC20176520//Rattus norvegicus mRNA for type II brain 4.1,
complete cds.
BRHIP20001630//Protein of unknown function DUF16
BRHIP20132860//Homo sapiens rhophilin-like protein mRNA, complete
cds.
BRHIP20143730//MYND finger
BRHIP20175420//Mus musculus partial mRNA for stretch responsive
protein 278 (sr278 gene).
BRHIP20236950//Outer Capsid protein VP4 (Hemagglutinin)
BRSSN20014260//RIBONUCLEASE INHIBITOR.
BRSSN20018690//Homo sapiens NY-REN-25 antigen mRNA, partial
cds.
BRSSN20021600//RING CANAL PROTEIN (KELCH PROTEIN).
BRSSN20177570//Phosducin
BRSTN10000830//Kelch motif// Kelch motif// Kelch motif// Kelch
motif
CTONG10000220//Mus musculus cerebellar postnatal development
protein-1 (Cpd1) mRNA, partial cds.
CTONG10000930//Armadillo/beta-catenin-like repeats
CTONG20027090//Glypican// Leucine Rich Repeat// Leucine Rich
Repeat
CTONG20076130//ZINC FINGER PROTEIN 185 (LIM-DOMAIN PROTEIN ZNF185)
(P1-A).
CTONG20096750//Disintegrin
CTONG20100240//Mus musculus radial spokehead-L protein (Rshl1)
mRNA, complete cds.
CTONG20139860//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete cds.
CTONG20143690//MYND finger
CTONG20149460//RING CANAL PROTEIN (KELCH PROTEIN).
CTONG20165050//Keratin, high sulfur B2 protein
CTONG20186320//RING CANAL PROTEIN (KELCH PROTEIN).
D3OST20013280//ARP2/3 COMPLEX 16 KDA SUBUNIT (P16-ARC).
D3OST20024360//Homo sapiens neuroendocrine differentiation factor
mRNA, complete cds.
D9OST20031370//Homo sapiens mRNA for partial putative
TCPTP-interacting protein (ptpip5 gene).
DFNES20014040//TRICHOHYALIN.
FCBBF10000630//Homo sapiens huntingtin interacting protein HYPB
mRNA, partial cds.
FCBBF10000770//Homo sapiens REC8 mRNA, partial cds.
FCBBF10005060//CELLULAR RETINALDEHYDE-BINDING PROTEIN (CRALBP).
FCBBF10005500//Keratin, high sulfur B2 protein
FCBBF20014270//ACYL-COA-BINDING PROTEIN (ACBP) (DIAZEPAM BINDING
INHIBITOR) (DBI) (ENDOZEPINE) (EP).
FCBBF20042170//Homo sapiens NIBAN mRNA, complete cds.
FCBBF30016320//SecA protein, amino terminal region
FCBBF30033050//Sm protein
FCBBF30054440//PLAT/LH2 domain
FCBBF30225660//Ank repeat// Ank repeat// Ank repeat// K+ channel
tetramerisation domain// BTB/POZ domain
FCBBF30233680//G10 protein
FCBBF30246630//H. sapiens mRNA for ZYG homologue.
FCBBF30250730//TRICHOHYALIN.
FCBBF30252520//Homo sapiens bicaudal-D (BICD) mRNA, alternatively
spliced, partial cds.
FCBBF30252800//NDRG1 PROTEIN (DIFFERENTIATION-RELATED GENE 1
PROTEIN) (DRG1) (REDUCING AGENTS AND TUNICAMYCIN-RESPONSIVE
PROTEIN) (RTP) (NICKEL-SPECIFIC INDUCTION PROTEIN CAP43).
FCBBF30252850//Mus musculus peripherial benzodiazepine receptor
associated protein (Pap7) mRNA, complete cds.
FCBBF30285280//Keratin, high sulfur B2 protein// Bacterial
regulatory proteins, gntR family
FEBRA20088360//ALPHA-ADAPTIN C (CLATHRIN ASSEMBLY PROTEIN COMPLEX 2
ALPHA-C LARGE CHAIN) (100 KDA COATED VESICLE PROTEIN C) (PLASMA
MEMBRANE ADAPTOR HA2/AP2 ADAPTIN ALPHA C SUBUNIT).
FEBRA20184330//Rattus norvegicus glutamate receptor interacting
protein 2 (GRIP2) mRNA, complete cds.
[0129] FEBRA20192420//Cyclin-dependent kinase inhibitor// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif FEBRA20196370//Cyclin-dependent kinase
inhibitor// IQ calmodulin-binding motif// IQ calmodulin-binding
motif// IQ calmodulin-binding motif// IQ calmodulin-binding motif//
IQ calmodulin-binding motif
FEBRA20225040//high-glucose-regulated protein 8
HCHON20001560//TRANSCRIPTION FACTOR-LIKE PROTEIN MORF4.
HCHON20003440//Homo sapiens cyclin-D binding Myb-like protein mRNA,
complete cds.
HCHON20010990//TPR Domain
HCHON20059870//Hypothetical protein.
HHDPC20034390//Cereal trypsin/alpha-amylase inhibito
HHDPC20057420//Mus musculus proline-rich protein (Bprp) mRNA,
complete cds.
HHDPC20064600//SUPPRESSOR PROTEIN SRP40.
HLUNG20023340//Mus musculus SLM-1 (Slm1) mRNA, complete cds.
KIDNE20007210//Xenopus laevis mRNA for RPA interacting protein
alpha (ripalpha gene).
KIDNE20028830//K-box region
KIDNE20115080//Homo sapiens mRNA for hNBL4, complete cds.
KIDNE20124400//Homo sapiens mRNA for ALEX1, complete cds.
KIDNE20127100//Drosophila melanogaster Diablo (dbo) mRNA, complete
cds.
KIDNE20127750//Homo sapiens partial mRNA for transport-secretion
protein 2.1 (TTS-2.1 gene).
KIDNE20190740//Rattus norvegicus SNIP-b mRNA, complete cds.
LIVER10004790//EF hand
LIVER20011130//Homo sapiens F-box protein FBL9 mRNA, partial
cds.
LIVER20064100//Ciona intestinalis mRNA for myoplasmin-C1, complete
cds.
LIVER20080530//Drosophila melanogaster forked mRNA for large Forked
protein, complete cds.
MAMGL10000830//Drosophila melanogaster L82B (L82) mRNA, complete
cds.
MESAN20036460//Corticotropin-releasing factor family
MESAN20127350//myelin expression factor-3
MESAN20141920//Human ovarian cancer downregulated myosin heavy
chain homolog (Doc1) mRNA, complete cds.
NT2NE20010400//Homo sapiens GL013 mRNA, complete cds.
NT2NE20122430//GLYOXYLATE-INDUCED PROTEIN.
NT2NE20158600//erythroid ankyrin-Synechocystis sp. (strain PCC
6803).
NT2RI20001330//Homo sapiens KE03 protein mRNA, partial cds.
NT2RI20009870//lunatic fringe precursor [Mus musculus]
NT2RI20046080//recA bacterial DNA recombination proteins
NT2RI20091730//Molluscan rhodopsin C-terminal tail
NT2RP60000850//Bos taurus RPGR-interacting protein-1 (RPGRIP1)
mRNA, complete cds.
NT2RP70080850//SPRY domain// Adenovirus EB1 55K protein/large
t-an
NT2RP70105210//Myc amino-terminal region
NT2RP70188710//Yeast PIR proteins
NT2RP70194450//Bacterial regulatory proteins, crp family
NTONG20052650//Gallus gallus Xin mRNA, complete cds.
NTONG20064400//REPETIN.
NTONG20064840//Mus musculus slp1 mRNA for synaptotagmin-like
protein 1, complete cds.
NTONG20066460//Mus musculus Gd mRNA for gasdermin, complete
cds.
NTONG20067090//Mus musculus mRNA for Sh3yl1, complete cds.
NTONG20070340//collagen alpha 1 (IX) chain
NTONG20083650//TPR Domain// TPR Domain// TPR Domain// PPR repeat//
TPR Domain// PPR repeat// TPR Domain
NTONG20088620//Homo sapiens genethonin 3 mRNA, partial cds.
OCBBF10000540//Mus musculus rjs (rjs) mRNA, complete cds.
OCBBF20019380//seizure related gene 6
OCBBF20022900//Homo sapiens SCHIP-1 mRNA, complete cds.
OCBBF20030280//Rattus norvegicus hfb2 mRNA, complete cds.
OCBBF20046470//ARFAPTIN 1.
OCBBF20049840//Homo sapiens mRNA for neurabin II protein.
OCBBF20068490//Mus musculus RW1 protein mRNA, complete cds.
OCBBF20071960//Coturnix coturnix japonica qMEF2D gene.
OCBBF20073540//Homo sapiens p30 DBC mRNA, complete cds.
OCBBF20121390//RING CANAL PROTEIN (KELCH PROTEIN).
OCBBF20127550//Outer Capsid protein VP4 (Hemagglutinin)
OCBBF20148730//RING CANAL PROTEIN (KELCH PROTEIN).
OCBBF20178150//Plasmodium falciparum ADA2-like protein gene,
partial cds.
PEBLM10000240//Domain found in Dishevelled, Eg1-10, and Ple
PROST20047270//CRAL/TRI0 domain.
PROST20112970//Sterile alpha motif (SAM)/Pointed domain// SAM
domain (Sterile alpha motif)
PUAEN10000850//Uncharacterized protein family UPF0025// Sec1
family
PUAEN20011880//Mus musculus mRNA for MIWI (piwi), complete cds.
PUAEN20051100//Mus musculus otogelin mRNA, complete cds.
PUAEN20108240//Drosophila melanogaster ankyrin 2 (Ank2) mRNA,
complete cds.
SKMUS20084740//Syndecan domain
SMINT20053300//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.
SMINT20071400//NOL1/NOP2/sun family
SMINT20101440//Human cisplatin resistance associated alpha protein
(hCRA alpha) mRNA, complete cds.
SMINT20110330//pKID domain
SMINT20122910//Mus musculus StAR-related protein 1-4E mRNA, partial
cds.
SMINT20131810//ENV polyprotein (coat polyprotein)
SMINT20168570//Homo sapiens mRNA for stabilin-1 (stab1 gene).
SPLEN20008390//Human placenta (Diff48) mRNA, complete cds.
SPLEN20084600//RING CANAL PROTEIN (KELCH PROTEIN).
SPLEN20128000//Xenopus laevis XMAB21 (Xmab-21) mRNA, complete
cds.
SPLEN20149110//Dishevelled specific domain
SPLEN20171470//Keratin, high sulfur B2 protein
SPLEN20194050//Homo sapiens HOTTL protein mRNA, complete cds.
SPLEN20214580//Mus musculus mdg1-1 mRNA, complete cds.
STOMA20057820//Uncharacterized protein family UPF0024
STOMA20063980//Collagen triple helix repeat (20 copies)
STOMA20069040//Keratin, high sulfur B2 protein
SYNOV20017080//UBX domain
TBAES20000590//Cytochrome P450// Cytochrome P450
TESTI20001170//HORMA domain
TESTI20031810//Bacterial luciferase// Domain of unknown function
DUF28
TESTI20044230//Mus musculus testis-specific Y-encoded-like protein
(Tspy11) mRNA, complete cds.
TESTI20098350//VAT-Nn domain
TESTI20157520//K+ channel tetramerisation domain// K+ channel
tetramerisation domain
TESTI20170350//Cystine-knot domain
TESTI20192800//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete cds.
TESTI20199750//TRICHOHYALIN.
TESTI20202650//Repeat in HS1/Cortactin
TESTI20229600//Drosophila melanogaster SP2353 mRNA, complete
cds.
TESTI20231920//Gag P30 core shell protein
TESTI20242830//E2 (early) protein, C terminal// Syndecan domain
TESTI20254540//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.
TESTI20320440//THIOREDOXIN.
TESTI20327680//EF hand// EF hand
TESTI20328280//KE2 family protein// Troponin
TESTI20351830//K-box region
TESTI20370020//Bleomycin resistance protein
TESTI20391210//IQ calmodulin-binding motif
TESTI20408150//Keratin, high sulfur B2 protein
TESTI20451990//SAP domain
[0130] TESTI20467970//Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain
THYMU20108310//Mouse NCBP-29 mRNA for PW29, complete cds.
THYMU20142040//WISKOTT-ALDRICH SYNDROME PROTEIN HOMOLOG (WASP).
THYMU20194360//Kelch motif
THYMU20239000//collagen alpha 1(XI) chain
TOVAR20004760//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat
TRACH20005020//Ank repeat// MutT-like domain
TRACH20007020//TRICHOHYALIN.
TRACH20048450//PROTEIN K4 (PROTEIN K3).
TRACH20068700//Homo sapiens adaptor protein CIKS mRNA, complete
cds.
TRACH20076760//Keratin, high sulfur B2 protein
TRACH20135520//TBC domain// Rhodanese-like domain
TRACH20141240//Mus musculus G21 protein mRNA, complete cds.
TRACH20183170//Rattus norvegicus Sprague-Dawley SM-20 mRNA,
complete cds.
UTERU20000740//Human fusion protein mRNA, complete cds.
UTERU20004240//CGI-96 protein
UTERU20006960//endoplasmic reticulum resident protein 58
UTERU20022940//Human (p23) mRNA, complete cds.
UTERU20046640//Mus musculus ldlBp (LDLB) mRNA, complete cds.
UTERU20065930//GTP-RHO BINDING PROTEIN 1 (RHOPHILIN).
UTERU20115740//Human PMS2 related (hPMSR3) gene, complete cds.
UTERU20179880//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
[0131] Further, the reason is that a polypeptide does not always
belong solely to a single category of the above-described
functional categories, and therefore, a polypeptide may belong to
any of the predicted functional categories. Besides, additional
functions can be found for the clones classified into these
functional categories by further analyses.
[0132] Since the polypeptide encoded by clones of the invention
contains full-length amino acid sequence, it is possible to analyze
its biological activity, and its effect on cellular conditions such
as cell proliferation and differentiation by expressing the
polypeptide as a recombinant polypeptide using an appropriate
expression system, injecting the recombinant into the cell, or
raising a specific antibody against the polypeptide.
[0133] The biological activities of respective polypeptides can be
analyzed by the methods as shown below.
Secretory Protein, Transmembrane Protein:
[0134] "Ion Channels" (Ed., R. H. Ashley, 1995) of "The Practical
Approach Series" (IRL PRESS), [0135] "Growth Factors" (Eds., I.
McKay, I. Leigh, 1993), [0136] "Extracellular Matrix" (Eds., M. A.
Haralson, J. R. Hassell, 1995); Glycoprotein-Related Protein:
[0137] "Glycobiology" (Eds., M. Fukuda, A. Kobata, 1993) of "The
Practical Approach Series" (IRL PRESS), [0138] "Glycoprotein
Analysis in Biomedicine" (Ed., Elizabeth F. Hounsell, 1993) of
"Method in Molecular Biology" (Humana Press) series; Signal
Transduction-Related Protein: [0139] "Signal Transduction" (Ed., G.
Milligan, 1992) of "The Practical Approach Series" (IRL PRESS),
[0140] "Protein Phosphorylation" (Ed., D. G. Hardie, 1993), or
[0141] "Signal Transduction Protocols" (Eds., David A. Kendall,
Stephen J. Hill, 1995) of "Method in Molecular Biology" (Humana
Press) series; Transcription-Related Protein: [0142] "Gene
Transcription" (Eds., B. D. Hames, S. J. Higgins, 1993) of "The
Practical Approach Series" (IRL PRESS), [0143] "Transcription
Factors" (Ed., D. S. Latchman, 1993); Enzyme and/or
metabolism-related protein: [0144] "Enzyme Assays" (Eds., ROBERT
EISENTHAL and MICHAEL J. DANSON, 1992) of "The Practical Approach
Series" (IRL PRESS); Cell Division and/or Cell
Proliferation-Related Protein: [0145] "Cell Growth, Differentiation
and Senescence" (Ed., GEORGE STUDZINSKI, 2000) of "The Practical
Approach Series" (IRL PRESS); Cytoskeleton-Related Protein: [0146]
"Cytoskeleton: Signalling and Cell Regulation" (Eds., KERMIT L.
CARRAWAY and CAROLIE A. CAROTHERS CARRAWAY, 2000) of "The Practical
Approach Series" (IRL PRESS), [0147] "Cytoskeleton Methods and
Protocols" (Ed., Gavin, Ray H., 2000) of "Method in Molecular
Biology" (Humana Press) series; Nuclear Protein and/or RNA
Synthesis-Related Protein: [0148] "Nuclear Receptors" (Ed., DIDIER
PICARD, 1999) of "The Practical Approach Series" (IRL PRESS),
[0149] "RNA Processing" (Eds., STEPHEN J. HIGGINS and B. DAVID
HAMES, 1994); Protein Synthesis and/or Transport-Related Protein:
[0150] "Membrane Transport" (Ed., STEPHEN A. BALDWIN, 2000) of "The
Practical Approach Series" (IRL PRESS), [0151] "Protein Synthesis
Methods and Protocols" (Eds., Martin, Robin, 1998) of "Method in
Molecular Biology" (Humana Press) series; Cellular Defense-Related
Protein: [0152] "DNA Repair Protocols" (Henderson, Daryl S., 1999)
of "Method in Molecular Biology" (Humana Press) series, [0153]
"Chaperonin Protocols" (Eds., Schneider, Christine, 2000);
Development and/or differentiation-related protein: [0154]
"Developmental Biology Protocols" (Eds., ROBERT EISENTHAL and
MICHAEL J. DANSON, 1992) of "Method in Molecular Biology" (Humana
Press) series; DNA- and/or RNA-Binding Protein: [0155] "DNA-Protein
Interactions Principles and Protocols" (Eds., Kneale, G. Geoff,
1994) of "Method in Molecular Biology" (Humana Press) series,
[0156] "RNA-Protein Interaction Protocols" (Eds., Haynes, Susan R.,
1999); ATP- and/or GTP-Binding Protein: [0157] "Signal Transduction
Protocols" (Eds., David A. Kendall, Stephen J. Hill, 1995) of
"Method in Molecular Biology" (Humana Press) series.
[0158] In the categorization, the clone predicted to belong to the
category of secretory and/or membrane protein means a clone having
hit data with some annotation, such as growth factor, cytokine,
hormone, signal, transmembrane, membrane, extracellular matrix,
receptor, G-protein coupled receptor, ionic channel, voltage-gated
channel, calcium channel, cell adhesion, collagen, connective
tissue, etc., suggesting that it was a secretory or membrane
protein, or a clone in which the presence of nucleotide sequence
encoding a signal sequence or transmembrane region was suggested by
the results of PSORT and SOSUI analyses for deduced ORF.
[0159] The clone predicted to belong to the category of
glycoprotein-related protein means a clone having hit data with
some annotation, such as glycoprotein, suggesting that the clone
encodes a glycoprotein-related protein.
[0160] The clone predicted to belong to the category of signal
transduction-related protein means a clone having hit data with
some annotation, such as serine/threonine-protein kinase,
tyrosine-protein kinase, SH3 domain, SH2 domain, etc., suggesting
that the clone encodes a signal transduction-related protein.
[0161] The clone predicted to belong to the category of
transcription-related protein means a clone having hit data with
some annotation, such as transcription regulation, zinc finger,
homeobox, etc., suggesting that the clone encodes a
transcription-related protein.
[0162] The clone predicted to belong to the category of
disease-related protein means a clone having hit data with some
annotation, such as disease mutation, syndrome, etc., suggesting
that the clone encodes a disease-related protein, or a clone whose
full-length nucleotide sequence has hit data for Swiss-Prot,
GenBank, UniGene, or nr, where the hit data corresponds to genes or
polypeptides which have been deposited in the Online Mendelian
Inheritance in Man (OMIM) (http://www.ncbi.nlm.nih.gov/Omim/),
which is the human gene and disease database described later.
[0163] The clone predicted to belong to the category of enzyme
and/or metabolism-related protein means a clone having hit data
with some annotation, such as metabolism, oxidoreductase, E. C. No.
(Enzyme commission number), etc., suggesting that the clone encodes
an enzyme and/or metabolism-related protein.
[0164] The clone predicted to belong to the category of cell
division and/or cell proliferation-related protein means a clone
having hit data with some annotation, such as cell division, cell
cycle, mitosis, chromosomal protein, cell growth, apoptosis, etc.,
suggesting that the clone encodes a cell division and/or cell
proliferation-related protein.
[0165] The clone predicted to belong to the category of
cytoskeleton-related protein means a clone having hit data with
some annotation, such as structural protein, cytoskeleton,
actin-binding, microtubles, etc., suggesting that the clone encodes
a cytoskeleton-related protein.
[0166] The clone predicted to belong to the category of nuclear
protein and/or RNA synthesis-related protein means a clone having
hit data with some annotation, such as nuclear protein, RNA
splicing, RNA processing, RNA helicase, polyadenylation, etc.,
suggesting that the clone encodes a nuclear protein and/or RNA
synthesis-related protein.
[0167] The clone predicted to belong to the category of protein
synthesis and/or transport-related protein means a clone having hit
data with some annotation, such as translation regulation, protein
biosynthesis, amino-acid biosynthesis, ribosomal protein, protein
transport, signal recognition particle, etc., suggesting that the
clone encodes a protein synthesis and/or transport-related
protein.
[0168] The clone predicted to belong to the category of cellular
defense-related protein means a clone having hit data with some
annotation, such as heat shock, DNA repair, DNA damage, etc.,
suggesting that the clone encodes a cellular defense-related
protein.
[0169] The clone predicted to belong to the category of development
and/or differentiation-related proteins means a clone having hit
data with some annotation, such as developmental protein, etc.,
suggesting that the clone encodes a development and/or
differentiation-related protein.
[0170] The clone predicted to belong to the category of DNA-and/or
RNA-binding protein means a clone having hit data with some
annotation, such as DNA-binding, RNA-binding, etc.
[0171] The clone predicted to belong to the category of ATP-and/or
GTP-binding protein means a clone having hit data with some
annotation, such as ATP-binding, GTP-binding, etc.
[0172] As to a protein involved in a disease, it is possible to
perform a functional analysis as described above, but also possible
to analyze correlation between the expression or the activity of
the protein and a certain disease by using a specific antibody that
is obtained by using expressed protein. Alternatively, it is
possible to utilize the database OMIM, which is a database of human
genes and diseases, to analyze the protein. Further, new
information is constantly being deposited in the OMIM database.
Therefore, it is possible for one skilled in the art to find a new
relationship between a particular disease and a gene of the present
invention in the most up-to-date database. The proteins involved in
diseases are useful for developing a diagnostic marker or medicines
for regulation of their expression and activity, or as a target of
gene therapy.
[0173] Also, as for a secretory protein, membrane protein, signal
transduction-related protein, glycoprotein-related protein, or
transcription-related protein, etc., search of the OMIM with the
following keywords resulted in the finding that the proteins are
involved in many diseases (the result of the OMIM search for
secrete and membrane proteins is shown below). Also, association
between proteins related to signal transduction or transcription
and diseases is reported in "Transcription Factor Research-1999"
(Fujii, Tamura, Morohashi, Kageyama, and Satake edit, (1999)
Jikken-Igaku Zoukan, Vol. 17, No.3), and "Gene Medicine" (1999)
Vol. 3, No.2). When cancer is used as an example, as described in
"Biology of Cancer" (S. Matsubara, 1992) of Life Science series
(Shokabo), many proteins are involved in cancers, which include
enzyme and/or metabolism-related proteins, cytoskeleton-related
proteins, cell division and/or cell proliferation-related proteins
as well as secretory proteins, membrane proteins, signal
transduction-related proteins, glycoprotein-related proteins,
transcription-related proteins. As clearly seen by the above
example, it is evident that not only disease-related proteins but
also secretory proteins, membrane proteins, signal
transduction-related proteins, glycoprotein-related proteins,
transcription-related proteins, etc. are often involved in
diseases, and thus they can be useful targets in the field of
medical industry.
[0174] The result of the OMIM search for secretory and membrane
proteins is shown below, in which the keywords,
[0175] (1) secretion protein,
[0176] (2) membrane protein,
[0177] (3) channel, and
[0178] (4) extracellular matrix were used.
[0179] Shown in the search result are only the accession numbers in
the OMIM. Using the number, data showing the relationship between a
disease and a gene or protein can be seen. The OMIM data has been
renewed everyday.
1) Secretion Protein
354 entries found, searching for "secretion protein"
[0180] *604667, *104760, *176860, *151675, *139320, *107400,
*604029, *118910, #200100, *176880, *603850, *147572, *604028,
*179513, *125950, *139250, *246700, *600946, *600560, *602926,
185860, *605083, *603215, *602421, *157147, *179512, *600174,
*109270, *604710, *138120, *179510, *600998, *179509, *170280,
*179511, *600626, *603831, *601489, *154545, *179490,
[0181] *603826, *122559, *603216, *102720, *147290, *164160,
*603062, *112262, *602672, *605435, *605322, *131230, *601652,
*603166, *601746, *601591, *179508, #160900, *104311, *600759,
*147545, *167805, #104300, *167770, #219700, *168470, *601684,
*602049, *601146, *605227, *602434, *602534, *114840, *603489,
*604323, *107470, *600753, *600768, *118825, *600564,
[0182] *604252, *173120, *134370, *192340, *308230, *600322,
*605359, *600046, *300090, 106160, *600041, #262500, *605563,
*150390, *158106, *182590, #103580, *104610, #173900, *134797,
*143890, #145980, *306900, *308700, *176300, *227500, *137350,
#154700, *138079, *600760, *107730, *142410, *147670, *124092,
*590050, *152760, *600509, *605646, *201910, *227600,
[0183] *152790, *300200, *300300, 300800, *138160, *107741,
*120150, *601199, *120180, *120160, *176730, *133170, *122560,
*107300, *137241, *120140, *101000, *193400, *217000, *272800,
*600937, #201710, *600377, #174800, *106100, #274600, *173350,
#177170, *147620, *214500, *131244, *202110, *120120, *601007,
*191160, *147470, *603372, *600733, *252800, *190160,
[0184] *138040, *158070, *162151, #125700, #130070, *113811,
*603355, *171060, *136435, #184700, *603732, *190180, *164008,
*186590, *120220, *604312, *152200, *138130, *605085, *605353,
*600840, #166210, *188545, *207750, *173360, *601933, #194050,
*153450, *138850, *253200, *307030, *157145, *600514, *600262,
*264080, *147380, *600281, #204000, #227810, *232200,
[0185] *188826, *232800, *161561, #166200, *188400, *153620,
*182099, *218040, #265800, *172400, #177200, *176805, #211600,
#214700, #176410, *152780, *600633, *601771, *301500, *605402,
*601922, *307800, *147892, *147720, *312060, #520000, *147660,
*106150, *602358, *107270, *601769, *147440, *604558, *131530,
*600270, *601610, *603692, *603401, *600423, *601604,
[0186] *603345, #125853, *602843, *142640, *603044, *605740,
*134830, *602779, *130660, *139191, *137035, *600761, *601340,
*600823, *107740, *130160, *600877, *605110, *600945, *130080,
*600957, #130050, *605580, *118444, *601124, *124020, 122470,
*120700, *603201, *137216, *601185, *138945, *218030, *600839,
#240600, #262400, #162300, *162330, *188450, #265850,
[0187] *263200, *162641, *300159, *601038, #191390, *201810,
*601398, *602384, *131240, *602423, *139392, *142703, *602663,
*232700, *602682, #602722, *602730, *600734, *188540, *182452,
*601538, *603061, *146880, *603140, *603160, *142704, #252650,
*182280, *125255, *603252, #131750, *182139, *182100, #259420,
#261100, *603493, *601745, *182098, *603795, *123812,
[0188] *600264, *147940, *180246, *180245, *118888, #604284,
*168450, *118455, *604398, *604433, *601919, *118445, *600031,
*604961, *605032, *605033, *171050, #171300, *131243, *109160,
*605254, 274900, #171400, *600042, *151670, *184600, *605470,
*605546, *176760, *602008, *102200, *605720, *600732, *605901
2) Membrane Protein
1489 entries found, searching for "membrane protein"
[0189] *130500, *605704, *305360, *153330, *173610, *109270,
*170995, *170993, *104776, *602333, *309060, *605703, *120920,
*605943, *602690, *159430, *600897, *133090, *601178, *602413,
*602003, *604405, *605940, *603237, *109280, *600378, *602173,
*107776, *602334, *602335, *125305, *601134, *309845, *605731,
*154045, *603241, *603718, *600594, *603214, *185881,
[0190] *603657, *600182, *603177, *605331, *601476, *605456,
*601114, *605190, *600723, *603904, *136950, *300222, *602879,
*185880, *605348, *300096, *602257, *177070, *310200, *603062,
*603344, *600039, *602977, *300100, *128240, *600959, *600322,
*227400, *186945, *600946, *602534, *602048, *182900, *601097,
*600267, *602625, *136430, *602421, *601047, *107450,
[0191] *143450, *603141, *184756, *164730, *159440, *154050,
*600579, *312080, *604202, *603700, *600447, *256540, *604691,
*158343, *600403, *602414, *137290, *176640, *176981, *600179,
*600754, *604456, *604693, *605875, *604605, *188860, *300172,
*602910, *604323, *219800, *601848, *60.3179, *600279, *602251,
#222700, *603831, *605072, *605377, *601028, *604155,
[0192] *108733, *104225, *601896, *601510, *173335, *107770,
*601767, *600046, *603850, *600040, *603784, *603234, 188560,
*605863, *121015, *605862, *605861, *186946, *604252, *603215,
*142461, *604597, *603143, *605264, *603735, *176860, *605536,
*176801, *180721, *603355, *104760, *131560, *310300, *602631,
*304700, #309400, *603142, *143890, *605431, *600753,
[0193] *115501, *176790, *600266, *601691, *168468, *601239,
*602216, #104300, *605613, *601595, *605550, *125950, *605475,
*602217, *602261, *603534, *602262, *604631, *190315, *601313,
*604306, *104311, *604672, *605000, *602461, *605548, *602296,
*604376, *121014, *121011, *600691, *604262, *139310, *304040,
*605445, *179514, *179512, *151460, #160900, *120130,
[0194] *128239, *601158, *601403, *176943, *601014, 300800,
*300294, *601757, *185470, *273800, *605034, *602887, #185000,
*604871, *603593, *603583, *605454, *104775, *605872, *141180,
*602713, *603531, *139150, *601531, *601832, *605452, *134651,
*604156, *120620, *605883, *604142, *166945, *605324, *600816,
*604699, *300112, *605182, *600164, *182180, *605071,
[0195] *300023, *605057, *308240, *300249, *176947, *176894,
*605081, *605035, *602044, *182860, *107271, *305100, *153390,
*113730, *602689, *180069, *603518, *300017, *191275, *177061,
*601693, *601789, *604241, *600934, *138160, *604424, *603868,
*600174, *600718, *600523, *604141, *601009, *605251, *600481,
*600874, *155550, *605227, *601017, *162230, 601138,
[0196] *604157, *601212, *600763, *604110, *604158, *601107,
*601326, 600621, *600587, 601137, *600917, *600855, *605058,
*194355, *605194, *603291, *102720, *136425, *170715, *603216,
*605547, *135630, *602926, *600168, *605002, *602474, *600157,
*603025, *603893, *231200, *120090, *601966, *131230, *604722,
*604721, *604515, *246700, *602101, *605628, *303630,
[0197] *605787, *602857, *602285, *605708, *602488, *605025,
*603817, *300051, *603293, *176878, *603646, 605707, 185860,
*112205, *300187, *602654, *120070, *603648, *604850, *602655,
*602514, *300118, *182309, *179590, *602701, *600759, *204200,
*604170, *175100, #103580, *147670, *306400, *143100, *182870,
*257220, *180380, #116920, *301000, *193300, *157147,
[0198] *131550, *139200, *139130, *190195, *605406, *155760,
*155960, *605734, *155970, *605385, *111700, *155975, *150370,
605709, *151430, *605438, *151510, *116952, *157655, *158105,
*605777, *176877, *153619, *120131, *185430, *109190, *120190,
*109170, *605093, *605250, *153432, *107777, *186590, *160993,
*605699, *605698, *605813, *605697, *605616, *605300,
[0199] *162060, *605219, *163970, *135620, *165040, *605478,
*604964, *103195, *604932, *604923, *605906, *605496, *605914,
*166490, 138277, *604915, *114070, *605213, *605933, *180297,
*101000, *191163, *191164, *605101, *603167, *600772, *603164,
*600708, *604001, *191328, *313440, *602672, *604009, *604299,
*192974, *604256, *603048, *600515, *604221, *602632,
[0200] *604196, *601179, 603290, *604661, *601023, *601110,
*304800, *203200, *300212, *602933, *603352, *208900, *604418,
*604838, *600551, #212140, *604837, *602049, *600552, *600553,
*300213, *602574, *600583, *600932, *603452, *604775, *516020,
*604617, *604464, *603498, *300145, *601523, *602694, *600632,
*604762, *604492, *400015, *604504, *601717, *601728,
[0201] *300242, *602426, *604194, *603821, *604730, *600695,
*603823, *603869, *300241, *600707, *603822, *602370, *602202,
*604193, *601181, *604089, *602507, *604195, *602306, *300284,
*601805, *601895, *601275, *604660, *600752, *603820, *604192,
*602207, *308230, *600894, *312600, *603199, *604029, *602500,
*102680, *235200, #256300, *601633, #219700, 262890,
[0202] *156225, *173470, *193400, *173910, *600354, *113705,
*600065, *107741, *107400, *600024, *131195, *113811, #118220,
*601638, *300011, *276903, *604144, *311770, *601758, #173900,
*604592, *120120, *179605, *603130, *603372, *110750, *222900,
*602509, *256100, *602469, *602281, *229300, *224100, *110900,
*190180, *261600, *602997, *603616, *603189, 601791,
[0203] *601567, *312700, *171060, *308700, *604027, *162643,
*516000, *176261, *604028, *314850, #145980, *601383, *600930,
*305900, *601253, *136350, *605537, *138140, *604033, *605070,
*139250, *300500, *603967, *300041, *603866, #130600, *120150,
*601050, *604942, *605204, *605248, *272750, *600163, *604235,
*600682, *107266, *306900, *191092, #262500, *600106,
[0204] *152790, *186720, *227650, *153700, *308380, *103390,
*605646, *164920, *604478, #252650, *173850, *173350, *602505,
*246530, *194380, *602575, *603030, #209920, *212138, #214100,
*605767, *600582, *189980, #176200, *604653, *604678, *256550,
*300037, *253700, #253300, #226700, *604766, #244400, *190000,
*188040, *604824, *214500, #237500, *232300, *605014,
[0205] *604477, *190930, *605124, *604475, *604594, #227810,
*306700, #301050, *600135, *600143, *605145, #269920, *300104,
*277900, *300135, *300231, *192500, *182138, *191190, *176805,
*600185, *186591, *604889, *603051, *165360, *147545, *601040,
#156575, *107269, *603009, *602934, *123825, *601081, *602924,
*163890, *600381, *602909, *150330, *109690, *123900,
[0206] *603434, *603491, *110700, *602581, *125647, #154700,
*114760, *141900, *603690, *120220, *601199, #145500, *601309,
*602382, *120325, *600877, *604205, *604090, *601497, *602377,
*605464, *138720, *603728, *120950, *604026, *600580, *601610,
*137167, *603960, *603931, *601880, *603126, *138190, *130130,
*601997, *601975, *600395, *516040, *600418, *600650,
[0207] *605245, *605172, *600509, *164761, *310400, *600308,
*605109, *600544, *600359, *600103, *605267, *312610, *176100,
*308100, *158070, *605123, *173325, #312750, *600839, *158120,
#604369, *604465, *173510, #161200, *151525, *605369, *604237,
*516050, #600886, *604517, *165180, *605381, *605399, *307800,
*604365, *155740, *147795, 601709, *604673, *147730,
[0208] *602122, *147557, *193245, *600978, *604990, *603261,
*603274, *601007, *131100, *602941, *107941, *146710, *276901,
*131244, *602872, *603411, *186357, *176290, *601066, *185050,
*232200, *143030, *601843, #236700, *604122, *142800, *134638,
*604985, *182380, *603930, *142410, *137060, *604586, *601193,
*120650, *252500, *253800, *120930, *604858, *605874,
[0209] 601274, *602158, *605873, *193210, *203100, *601295,
*604095, #201710, *126150, *108740, #205400, *601373, *300167,
*109545, *602894, *603361, #300257, *266200, *603401, *131390,
*180470, *605908, *604798, #221770, *223360, *180901, *605641,
*605745, *604018, *300200, *604603, *230800, *602676, #604004,
*605692, *602640, *601599, *134637, *245900, *118425,
[0210] 601614, *605725, *120110, *300189, *300035, *603102,
*250800, *602282, *602458, *123610, *603754, *300278, *601463,
*300224, *601581, *182160, *601653, *139191, *601733, *600748,
*142460, *601194, *152390, *153620, *601615, *601814, *601617,
*601613, *300191, #308300, *600798, 601858, *601872, *601597,
#601588, *600821, *147840, *152427, *138850, *600823,
[0211] *601492, *300256, *600840, *300267, *601411, *139080,
*139090, 600851, *300334, *179080, *602095, *601284, *601282,
#177200, *601681, *601252, *176000, *602184, *602188, #266510,
#154020, *186711, *257200, *601711, *600667, *602241, *186745,
*255125, *300126, *600644, *123890, #255120, #175200, *600004,
*302060, *123580, *186760, *122561, *602316, *600017,
[0212] *120940, 140300, *151690, *120700, *602354, *600019,
*600857, *182175, *600536, *158380, *600516, *120290, *600493,
*182310, #252010, *182530, *186830, *601839, *142790, *159465,
*118990, *250790, *248600, #248250, *186845, *601153, *142600,
*116930, *114860, *171834, #303600, *186880, *600444, *142871,
*601852, *602602, *602607, *114207, *186910, #232220,
[0213] 600880, *134635, *112203, #112100, *111680, *231680,
*311030, *111250, *111200, *134390, #226670, #145600, *226200,
*602714, *171760, *133550, *602727, *161555, *602744, *602746,
#131705, *602835, *600423, *176267, *602859, #600918, 277175,
*602874, *601020, *109770, *600170, *217070, *173515, *602893,
*147280, *154360, *171050, *108780, *176257, *600979,
[0214] *600377, *108360, *204500, *170260, *146880, *154582,
*601011, *600997, *602992, *201475, *603005, *190198, *147360,
#270400, *600238, #164970, *306250, #126600, *193065, #181350,
*106180, *602136, *600937, *603086, *603087, *307030, *182099,
*103320, *601683, #192430, *103180, *102681, *192321, *600244,
*191740, *191315, *603152, *102642, *191305, #266140,
[0215] *100500, *600867, *604585, *604404, *604345, *603201,
*605430, *603207, *603208, *605433, *604101, *603969, *605896,
*604616, *605851, *605768, *604576, *605754, *605730, *605477,
*603263, *605538, *603283, *604402, *605453, *605427, *603302,
*605458, 603313, *604415, *603345, *605541, *603353, *605295,
*603879, *605268, *605266, *605246, *603377, *603380,
[0216] *605181, *604203, *603425, *603867, *605106, *605017,
*603842, *604936, *603510, *604857, *605932, *605816, *603765,
*603551, *605357, *605237, *604204, *603594, *605110, *604190,
*603861, *604962, *603639, *603644, *605007, *605349, *604943,
*604918, *604907, *603667, *603681, *605396, *605561, *603712,
*603713, *605688, *605942, *604878, *604843, *604659,
[0217] *604671, *603798, *604682, *604056, *604705, *603749,
602586, *603647, *602515, #602475, *603717, *602359, *602372,
*602380, *602518, *603652, *602573, *603626, 602587, *603598,
*602871, *603613, *603750, *603875, *602608, *602666, *602345,
*602935, *603564, *603548, *603927, 601876, *602343, *603943,
*603787, *601730, *601611, *602679, *603788, *602243,
[0218] 603790, *601535, *603796, *601488, *601485, *602314,
*601478, *604047, *604048, *602297, *604057, *602715, *602192,
*601459, *601416, *603833, *602190, *604102, *602106, *604111,
*602724, *603499, *602736, *601123, *601002, *600923, *601987,
*604149, *601929, *600910, *600900, *600864, *604165, *600782,
*602836, *600769, *600742, *602783, *601905, *600535,
[0219] *604198, *601901, *600534, *602876, *603356, *600530,
*604216, *604217, *602890, *602905, *600465, *600464, *600446,
*602891, *603366, *601894, *604272, *603926, *603312, *600368,
*602914, *600327, *603151, *603202, 602911, *602974, *603006,
*601883, *603008, *600074, *603007, *603046, #603903, *604433,
*600016, *603925, *516005, *516004, *516003, *601756,
[0220] *604487, *516001, *313475, *313470, #307810, *604527,
*604528, *601745, *604551, *604555, *603243, *603242, *603061,
*603063, *603217, *300335, *300283, *300281, *604600, *300197,
*603097, *603220, *601625, *604623, *603118, *601590, *604646,
*300008, *601568, *300007, *275630, *601533, #275200, *270200,
#261550, *604031, *604683, #254800, *251100, #242300,
[0221] *604058, *604720, *240500, *233690, #232240, #226730,
*223100, *222100, #220100, *216950, *604832, 212750, 212067,
*604066, *193067, 601315, *193001, *604862, *604870, *191306,
*600385, *604879, *191191, *601296, *604914, *190181, *604119,
#188550, *604925, *188410, #601287, *604939, *188380, *604126,
*604945, *604148, *188060, *604982, *186854, *604988,
[0222] *186360, *186355, *185250, *600916, *605008, *605009,
185020, *600734, *605024, *182331, *605032, *605033, *182305,
*180903, #179800, *179610, *605060, *179410, *178990, *176802,
*605080, *176266, *176263, *176260, *600732, *173490, *604199,
*173445, *173391, 172290, *605147, *605149, *171890, *600528,
*171833, *605185, #170500, *605193, #168000, *605196,
[0223] *167055, *605205, *605208, 166900, *605216, *162651,
*162010, *600504, #161400, *604253, #160800, *159460, *154540,
*605254, *605261, *153634, *600429, *153337, *600424, *605292,
#604286, #152700, 152423, *152310, *151625, *600153, *604313,
*151523, *150325, *150320, *150292, *603150, *150290, *150210,
*605410, *605415, *605416, *605417, *605421, *603149,
[0224] *604349, *147940, *600282, *147880, *146928, *146661,
*600150, *146630, *142622, *600018, *605461, *138981, *138590,
*600023, *138330, *605495, *138297, *605512, *138230, #136900,
#301310, *516006, *605545, *605546, *136131, *134660, *134350,
*516002, *605589, *131235, #130050, *605625, *126455, *126064,
#125310, *605670, *604534, *125240, *123836, *123830,
[0225] *123620, *605702, #122200, *120980, *120360, *118510,
*114835, *605710, *605716, *605722, *114217, *604561, *113810,
*111740, #110800, *605748, *605752, *604564, *110600, *603160,
*109610, *605784, #107480, *107273, *603192, *300169, *106195,
*105210, *104615, *104614, *104210, *103850, 103581, *605876,
*605877, *605879, *103220, *605887, *300150, *102910,
*102670, *102576, *605916, *604629, *102575, *102573, *300132,
*101800, *605947
3) Channel (Member of Membrane Protein)
361 entries found, searching for "channel"
[0226] *176266, *600724, *182390, *123825, *114208, *114206,
*176267, *114205, *601784, *600937, *114204, *603415, *600053,
*114207, *114209, *605427, *604527, *604528, *600760, *601011,
*192500, *118425, *600228, *176261, *602235, *600761, *600359,
*300008, *182389, *600877, *602232, *176263, *182391, *601328,
*600054, *603939, *602208, *601534, *600504, *602323,
[0227] *603208, *601958, *603537, *601012, *601327, *600734,
*602780, *602781, *604433, *603220, *182392, *605874, *605873,
*601745, *603888, *603219, *602604, *603796, *302910, *602866,
*601013, *602905, *602906, *603967, *600163, #170500, *152427,
*180901, *176260, #601462, *603951, *601141, *604492, *600702,
*602023, *600308, *602754, *107776, *176257, *602024,
[0228] *601949, *605222, *601142, *602983, *193245, *600681,
*176265, *600235, *176262, *176258, *605206, *604427, *605411,
*603305, *601219, *600150, *604065, *602343, *605223, *605720,
*603906, *138249, *138253, *600843, *604385, *600003, *600935,
*603940, *602727, *602158, 602911, *600397, *602726, *600845,
*605080, *600580, *602872, *602106, *176264, *603953,
[0229] *605722, *300110, *138252, *604111, *602717, *602420,
*600570, 600844, *603493, *600932, *605716, *138254, *603652,
*300138, *605410, *176268, *605214, *605696, *300334, *604660,
*176256, *605879, *603749, *603583, *602345, *604661, *603787,
603313, *602982, *604337, *600846, *604662, *300328, *300281,
*602566, *602836, *604003, *603788, *603651, *602421,
[0230] *107777, #177200, *100725, #219700, *100690, *100710,
#160800, #603830, #183086, *600509, #220400, #601144, *173910,
*180902, *605692, #264350, #160900, #145600, #255700, *602076,
*603061, *601313, *154275, #604233, *604532, #108500, #121201,
#170400, *300225, *121014, *139311, #125800, #160120, *118503,
601439, #141500, #168300, *304040, #601887, #256450,
[0231] *186945, *154276, #300009, #216900, *600040, *601014,
*601042, *602512, *601383, *605445, *602368, *603831, #117000,
*601218, *108745, *605248, #177735, #173900, *601212, *182139,
*601059, *600039, *601485, *180903, *186360, *603319, #600101,
*118509, *600109, #121200, *600170, *604187, *176975, *137163,
#310468, #263800, #262300, *603750, *600229, *124030,
[0232] *602251, #603829, *137143, #145500, *600669, *147450,
*154050, *603353, *600516, *601157, *600855, *601154, *602522,
*249210, *600968, #252650, *171060, *600919, *156490, #259700,
#601678, *601764, #310500, *131244, *300041, *121011, *125950,
*114180, *602974, *600637, *113730, *118504, *605145, *604669,
*118800, *121013, *121015, *138491, *600421, *104610,
[0233] *604045, *604594, *131230, *605487, *138247, *600467,
#602485, *602481, *138251, *137192, *602403, 600851, *277900,
*603785, *603152, *603199, *603475, #168600, #272120, *170280,
*603852, #241200, *603053, *600465, #603034, *142461, *164920,
*137164, *600884, *600442, *123885, *604001, *600232, *232200,
*171050, *602103, *602014, *300211, *600983, *602887,
[0234] *604415, *604418, *300242, #300071, *604471, *600837,
168350, *118511, 193007, *600300, *604654, #601820, *180297,
*600046, *603853, *604678, *604693, #604772, *118508, *603855,
*605204, #254210, *182099, *182307, #130600, *601109, *114080,
*300103, *182860, *605438, *601129, *603964, *600019, *516060,
#185000, *138079, *104210, *605818, *603418, *305990, *305450
4) Extracellular Matrix
218 entries found, searching for "extracellular matrix"
[0235] *605912, *603479, *602201, *604633, *601418, *601548,
*115437, *154870, *600754, *602261, *602285, *602262, *134797,
*120361, *604629, *604871, *603321, *603320, *601807, #154700,
*116935, *185261, *120360, *185250, *605470, *603767, *253700,
*190180, *128239, *308700, *276901, *193300, *120324, *188826,
*602109, *155760, *600514, *600261, #177170, *600536,
[0236] *147557, #116920, *150240, *601313, *120140, 601614,
*605158, *120150, *120180, #200610, *605127, *193400, *192240,
#173900, *152200, #136900, *135821, #130070, *120320, *120220,
*112260, *310200, *600900, *600262, *605670, *600985, *179590,
#245150, *602574, *601463, 183850, *601211, *604241, *600758,
*186745, *604710, *602369, *602090, *190182, *192975,
[0237] *602178, *230740, *600065, *601652, *158106, *190181,
*156790, #158810, *193210, *155120, *192977, *193065, #226700,
*187380, *231050, *182120, *188060, *186355, 163200, *164010,
#156550, *151510, *150370, *253800, *156225, *150325, #194050,
*150290, *216550, *147620, *600215, *222600, *147559, *165380,
*182888, *600491, *146650, *146640, *600564, *600596,
[0238] *600616, *600700, *600742, *138297, *182889, *154705,
*600930, *301870, *153619, *601050, *601090, *601105, *165070,
*305370, *135820, *130660, *310300, *601492, *128240, *601587,
#126600, *601636, *600119, *601692, *601728, *125485, 601858,
*601915, *602048, *175100, *602108, *121010, *600245, *120470,
*120328, *120325, *602264, *120280, *602366, *600309,
[0239] *602402, *602415, *602428, *602453, *602505, #166210,
*602600, *602941, *603005, *603196, 603209, *603221, *603234,
*603319, *120250, *120210, *120120, *603489, *603551, *118938,
*603799, *603842, *603924, *603963, *604042, *604063, *604149,
*604160, *601028, *604467, *604510, *604592, *116930, *116806,
*601284, *604724, *604806, *604807, *604808, *107269,
*605007, *605008, *605009, *600214, *600076, *605174, *605175,
*605292, *605343, *605351, #600204, *605497, *605546, *605587,
*605623, *600211, *605702, *103320
[0240] In addition to these, the various keywords shown in the
above-mentioned categorization or others can be used for the OMIM
search and the result may suggest the involvement thereof in
diseases.
[0241] Further, the use of nucleotide sequences of cDNAs of the
present invention enables analyzing the expression frequency of
genes corresponding to the cDNAs. In addition, functions of the
genes can be predicted based on the information obtained by the
expression frequency analysis.
[0242] There are several methods for analyzing the expression
levels of genes involved in diseases. Differences in gene
expression levels between diseased and normal tissues are studied
by the analytical methods using, for example, Northern
hybridization, RT-PCR, DNA microarray, etc. (Experimental Medicine,
Vol. 17, No. 8, 980-1056 (1999); Cell Engineering (additional
volume) DNA Microarray and Advanced PCR Methods, Muramatsu &
Nawa (eds.), Shujunsya (2000)). By computer analysis, in addition
to these analysis methods, the nucleotide sequences of expressed
genes can be compared to analyze the expression frequency. For
example, there is a database called "BODYMAP"; gene clones are
extracted at random from cDNA libraries of various tissues and/or
cells, and the clones homologous to one another are assigned to a
single cluster based on the information of nucleotide sequence
homology at the 3'-end; genes are classified into any clusters, and
the numbers of clones in the respective clusters are compared to
gain the information on expression frequency
(http://bodymap.ims.utokyo.ac.jp/).
[0243] When explicit difference in the expression levels between
diseased tissues and normal tissues is observed for a gene by these
analytical methods, it can be conclude that the gene is closely
involved in a disease or disorder. Instead of diseased tissues,
when gene expression is explicitly different between normal cells
and cells reproducing disease-associated specific features, it can
be concluded that the gene is closely involved in a disease or
disorder.
[0244] From the 2443 clones whose full-length nucleotide sequences
had been revealed, genes involved in particular pathology or
functions were selected by the use of databases shown below (see
Example 7; "Expression frequency analysis in silico"). The database
used in the analyses of the present invention contains nucleotide
sequences of 1,402,070 clones, and the population of the database
is large enough for the analysis. The sequence information in the
database was obtained by selecting cDNA clones at random from cDNA
libraries derived from the various tissues and cells shown in
Example 1 and determining the 5'-end sequences thereof.
[0245] Then, the nucleotide sequences of respective clones in this
database were categorized (clustered) based on the nucleotide
sequence homology determined with a search program; the number of
clones belonging to every cluster of each library was determined
and normalized; thus, the ratio of a certain gene in a cDNA library
was determined. This analysis provided the information of the
expression frequency of a gene in a tissue or cell that is the
source of the cDNA library.
[0246] Then, in order to analyze the expression of genes
corresponding to the nucleotide sequences of cDNAs of the present
invention in tissues and cells, the libraries from the tissues or
cells, which had been used in the large-scale cDNA analyses, were
taken as subjects to compare the expression levels between
different tissues or cells. Namely, the expression frequency was
analyzed by comparing the previously normalized values between
tissues or cells from which 600 or more cDNA clones whose
nucleotide sequences had been analyzed were derived. The result of
this analysis showed that the cDNA clones corresponded to the genes
involved in the pathology and functions, which are indicated below.
Each value in Tables 3 to 51 indicated below represents a relative
expression frequency; the higher the value, the higher the
expression level.
Osteoporosis-Related Genes
[0247] Osteoporosis is a pathology in which bones are easily broken
owing to overall decrease in components of bone. The onset
correlates to the balance between the functions of osteoblast
producing bone and osteoclast absorbing bone, namely bone
metabolism. Thus, the genes involved in the increase of osteoclasts
differentiating from precursor cells of monocyte/macrophage line
(Molecular Medicine 38. 642-648. (2001)) are genes involved in
osteoporosis relevant to bone metabolism.
[0248] A nucleotide sequence information-based analysis was carried
out to identify the genes whose expression frequencies are higher
or lower in CD34+ cell (cell expressing a glycoprotein CD34)
treated with the osteoclast differentiation factor (Molecular
Medicine 38. 642-648. (2001)) than in the untreated CD34+ cell,
which is the precursor cell of monocyte/macrophage line. The result
of comparative analysis for the frequency between the cDNA
libraries prepared from the RNA of CD34+ cells (CD34C) and from the
RNA of CD34+ cells treated with the osteoclast differentiation
factor (D30ST, D60ST or D90ST) showed that the genes whose
expression levels were different between the two were 56 clones
indicated in Table 3. These clones are involved in
osteoporosis.
Genes Involved in Neural Cell Differentiation
[0249] Genes involved in neural cell differentiation are useful for
treating neurological diseases. Genes with varying expression
levels in response to induction of cellular differentiation in
neural cells are thought to be involved in neurological
diseases.
[0250] A survey was performed for genes whose expression levels are
varied in response to induction of differentiation (stimulation by
retinoic acid (RA) or growth inhibitor treatment after RA
stimulation) in cultured cells of a neural strain, NT2. The result
of comparative analysis of cDNA libraries derived from
undifferentiated NT2 cells (NT2RM) and the cells subjected to the
differentiation treatment (NT2RP, NT2R1 or NT2NE) showed that the
genes whose expression levels were different between the two were
288 clones indicated in Table 4. These genes are neurological
disease-related genes.
Cancer-Related Genes
[0251] It has been assumed that, distinct from normal tissues,
cancer tissues express a distinct set of genes, and thus the
expression thereof can contribute to the carcinogenesis in tissues
and cells. Thus, genes whose expression patterns in cancer tissues
are different from those in normal tissues are cancer-related
genes. Search was carried out for the genes whose expression levels
in cancer tissues were different from those in normal tissues.
[0252] The result of comparative analysis of cDNA libraries derived
from breast tumor (TBAES) and normal breast (BEAST) showed that the
genes whose expression levels were different between the two were
35 clones indicated in Table 5.
[0253] The result of comparative analysis of cDNA libraries derived
cervical tumor (TCERX) and normal cervical duct (CERVX) showed that
the genes whose expression levels were different between the two
were 11 clones indicated in Table 6.
[0254] The result of comparative analysis of cDNA libraries derived
from colon tumor (TCOLN) and normal colon (COLON) showed that the
genes whose expression levels were different between the two were
25 clones indicated in Table 7.
[0255] The result of comparative analysis of cDNA libraries derived
from esophageal tumor (TESOP) and normal esophagus (NESOP) showed
that the genes whose expression levels were different between the
two were 41 clones indicated in Table 8.
[0256] The result of comparative analysis of cDNA libraries derived
from kidney tumor (TKIDN) and normal kidney (KIDNE) showed that the
genes whose expression levels were different between the two were
175 clones indicated in Table 9.
[0257] The result of comparative analysis of cDNA libraries derived
from liver tumor (TLIVE) and normal liver (LIVER) showed that the
genes whose expression levels were different between the two were
47 clones indicated in Table 10.
[0258] The result of comparative analysis of cDNA libraries derived
from lung tumor (TLUNG) and normal lung (HLUNG) showed that the
genes whose expression levels were different between the two were
62 clones indicated in Table 11.
[0259] The result of comparative analysis of cDNA libraries derived
from ovary tumor (TOVER) and normal ovary (NOVER) showed the genes
whose expression levels were different between the two were 23
clones indicated in Table 12.
[0260] The result of comparative analysis of cDNA libraries derived
from stomach tumor (TSTOM) and normal stomach (STOMA) showed that
the genes whose expression levels were different between the two
were 70 clones indicated in Table 13.
[0261] The result of comparative analysis of cDNA libraries derived
from uterine tumor (TUTER) and normal uterus (UTERU) showed that
the genes whose expression levels were different between the two
were 236 clones indicated in Table 14.
[0262] The result of comparative analysis of cDNA libraries derived
from tongue cancer (CTONG) and normal tongue (NTONG) showed that
the genes whose expression levels were different between the two
were 232 clones indicated in Table 15.
[0263] These genes are involved in cancers.
[0264] Further, there is a method to search for genes involved in
development and differentiation, which is the expression frequency
analysis in which the expression levels of genes are compared
between developing and/or differentiating tissues and/or cells and
adult tissues and/or cells. The genes involved in tissue
development and/or differentiation are genes participating in
tissue construction and expression of function, and thus are useful
genes, which are available for regenerative medicine aiming at
convenient regeneration of injured tissues.
[0265] By using the information of gene expression frequency gained
from the database of 5'-end nucleotide sequences described above,
genes involved in development or differentiation of particular
tissues were selected from the 2443 clones whose full-length
nucleotide sequence had been revealed (see Example 7).
[0266] The result of comparative analysis of cDNA libraries derived
from fetal brain (FCBBF, FEBRA or OCBBF) and adult brain (BRACE,
BRALZ, BRAMY, BRAWH, BRCAN, BRCOC, BRHIP, BRSSN, BRSTN or BRTHA)
showed that the genes whose expression levels were different
between the two were 1195 clones indicated in Tables 16 to 48.
[0267] The result of comparative analysis of cDNA libraries derived
from fetal heart (FEHRT) and adult heart (HEART) showed that the
genes whose expression levels were different between the two were
45 clones indicated in Table 49.
[0268] The result of comparative analysis of cDNA libraries derived
from fetal kidney (FEKID) and adult kidney (KIDNE) showed that the
genes whose expression levels were different between the two were
118 clones indicated in Table 50.
[0269] The result of comparative analysis of cDNA libraries derived
from fetal lung (FELNG) and adult lung (HLUNG) showed that the
genes whose expression levels were different between the two were
63 clones indicated in Table 51. These genes are involved in
regeneration of tissues and/or cells.
[0270] The expression frequency or the like can be analyzed by PCR
based on the nucleotide sequences of cDNAs of the present
invention. There are some known methods for comparing the
quantities of amplification products obtained by PCR. For example,
the band intensities can be determined by ethidium bromide
staining. With R1-labeled or fluorescently labeled primers, the R1
signal or fluorescence intensity can be assayed for the quantity of
labeled amplification products. Alternatively, the quantity of
amplification products can also be determined by measuring the R1
signal or the fluorescence intensity from the R1-labeled or
fluorescently labeled probe hybridizing to the products. The assay
results thus obtained are compared and then the clones exhibiting
differences in the expression levels can be selected.
[0271] There are some quantitative PCR methods: a PCR method using
internal standards; a competitive PCR, in which the quantification
is achieved by adding, to a sample, a dilution series of a known
quantity of a template RNA and by comparing the quantity of an
amplification product derived from the RNA of interest with the
quantity of an amplification product derived from the template RNA.
These methods overcome the problems of errors in the amount of
amplification products among tubes and of the plateau effect.
ATAC-PCR (Adaptor-tagged competitive PCR) is a method of
competitive PCR which is practiced by using multiple adapters of
different sizes attached to a gene whose 3'-end nucleotide sequence
has previously been determined. The ratio of expression frequency
of a single mRNA species from a number of tissues (cells) can be
assayed in a single step (Nucleic Acids Research 1997, 25(22):
4694-4696; "DNA Micro-array and Advanced PCR Techniques", Cell
Technology, supplement, Eds., Muramatsu and Nawa (Shujunsha, 2000):
104-112).
[0272] If it is observed, by using these analytical methods, that
the expression levels of genes are evidently varied during major
cellular events (such as differentiation and apoptosis), the genes
are involved in the cellular events and accordingly are candidates
for disease- and/or disorder-related genes. Further, genes
exhibiting tissue-specific expression are genes playing important
parts in the tissue functions and, therefore, can be candidates for
genes involved in diseases and/or disorders affecting the
tissues.
[0273] For example, inflammation is an important biological
response that is known to be involved in various diseases. The
representative inflammation-inducing factors include TNF-a (Tumor
Necrosis Factor-alpha). There exists a signaling cascade activated
by TNF-.alpha. stimulations, wherein NF-.kappa.B is a transducing
molecule (Cell 1995, 80:529-532). It has also been revealed that
many inflammation-related genes, including IL-2, IL-6 and G-CSF,
are varied in the expression levels thereof in response to the
signal through the pathway (Trends Genet. 1999, 15(6): 229-235). It
is assumed that genes whose expression levels are varied in
response to the stimulation of TNF-.alpha. also participate in
inflammation.
[0274] Further, the infection of Helicobacter pylori to the gastric
epithelia is known to cause gastritis and gastroduodenal ulcer
(Mebio 2000, July, 17(7): 16-33). Thus, the genes whose expression
levels are altered depending on co-culturing cells with
Helicobacter pylori may be involved in gastritis and gastroduodenal
ulcer. A recent study has suggested that Helicobacter pylori
strongly activates the NF-KB pathway(Gastroenterology 2000, 119:
97-108).
[0275] THP-1 cell, which is a human monocyte cell line, was
cultured in the presence of TNF-.alpha. (Tumor Necrosis
Factor-alpha) The genes whose expression levels were altered owing
to the presence of TNF-.alpha. were searched for, and the result
showed that the clones whose expression levels were increased owing
to the presence of TNF-.alpha. were ASTRO20152140,
BRACE20057620,
[0276] BRACE20060720, BRACE20090440, BRACE20152870, BRACE20229280,
BRAMY20002770, BRAMY20266850, BRAMY20280720, BRAWH20106180,
BRAWH20122770, BRHIP20096170, BRHIP20111200, BRHIP20186120,
BRHIP20194940, BRHIP20207430, BRSSN20152380, CTONG20095270,
CTONG20100240, CTONG20158150,
[0277] CTONG20265130, D3OST20006540, D9OST20031370, FCBBF20071860,
FCBBF30251420, FCBBF30252520, FCBBF40001420, FEBRA20017050,
FEBRA20082100, HCHON20011160, KIDNE20141190, KIDNE20163880,
KIDNE20182690, LIVER10004790, LIVER20038540, LIVER20085800,
MESAN20130220, MESAN20174170, NT2NE20158600, NT2RI20005750,
NT2RP70110860, NT2RP70169110, NT2RP70175670, NT2RP70188710,
PERIC20002140, PLACE60155130, PROST20120160, PROST20149250,
PROST20161950, PUAEN20015260, SKNSH20080430, SMINT20051610,
SMINT20060780, SMINT20161220, SMINT20163960, SPLEN20101190,
SPLEN20157300, SPLEN20163560, SPLEN20214580, SPLEN20279950,
STOMA20048520, TESTI20076850, TESTI20087620, TESTI20108720,
TESTI20220100, TESTI20239510, TESTI20266740, TESTI20342430,
TESTI20370020, TESTI20391210, TESTI20401020, TESTI20415640,
THYMU20130890, THYMU20286290, TRACH20060150, TRACH20099340,
UTERU20004240, UTERU20068990, UTERU20119060.
[0278] On the other hand, the clones whose expression levels were
decreased owing to the presence of TNF-.alpha.were
ASTRO20032120,
[0279] ASTRO20084250, ASTRO20181690, BRACE20062640, BRACE20067430,
BRACE20235400, BRALZ20018340, BRALZ20069760, BRALZ20075450,
BRAMY20163270, BRAMY20204450, BRAMY20218670, BRAMY20229800,
BRAWH10000930, BRAWH20107540, BRAWH20132190, BRAWH20158530,
BRCAN20273340, BRHIP20105710, BRHIP20186120,
[0280] BRSSN20176820, CTONG20095290, DFNES20031920, FCBBF30033050,
FCBBF30071520, FCBBF30083820, HCHON20008980, HCHON20022470,
HHDPC20034390, KIDNE20028720, KIDNE20079440, KIDNE20127750,
KIDNE20148900, LIVER20011130, MAMGL10000830, MESAN20127350,
NT2NE20181650, NT2RI20023160, NT2RP70102350, NT2RP70157890,
NTONG20029480, OCBBF20020830, OCBBF20041680, OCBBF20061720,
OCBBF20127040, OCBBF20139260, OCBBF20178990, PEBLM20013120,
PLACE60003480, PLACE60181070, PROST20151240, PUAEN20003740,
PUAEN20011880, PUAEN20078980, PUAEN20085150, SKNSH20080430,
SMINT20001760, SMINT20047810, SMINT20108530, SPLEN20158990,
SPLEN20283650, STOMA20010250, STOMA20057820, TESTI20060400,
TESTI20161970, TESTI20275620, TESTI20369690, TESTI20386230,
TESTI20392250, TESTI20409440, TESTI20424730, THYMU20095960,
THYMU20111180, THYMU20226600, THYMU20253250, THYMU20272490,
TRACH20153810, UTERU20176130, UTERU20186740.
[0281] These clones are inflammation-related genes.
[0282] MKN45, which is a gastric cancer cell line, was co-cultured
with Helicobacter pylori. The genes whose expression levels were
altered owing to the presence of Helicobacter pylori were searched
for, and the result showed that the clones whose expression levels
were increased owing to the presence of Helicobacter pylori were
ADRGL20067670, BLADE20004630,
[0283] BRACE20039040, BRACE20151320, BRACE20229280, BRACE20235400,
BRALZ20058880, BRAMY20060920, BRAMY20184670, BRAMY20218670,
BRAMY20229800, BRCAN20147880, BRHIP20196410, BRHIP30004880,
BRSSN20187310, CD34C30004940, CTONG20265130, DFNES20031920,
FCBBF30278630, FCBBF40001420,
[0284] HHDPC20095280, KIDNE20130450, LIVER20011130, LIVER20038540,
NT2NE20172590, NT2RP70169110, OCBBF20085200, OCBBF20180840,
PEBLM10000240, PLACE60003480, PROST20120160, PROST20151240,
PUAEN20011880, SKMUS20031680, SKNSH20080430, SMINT20056210,
SMINT20105000, SPLEN20019450, SPLEN20211570, STOMA20048520,
TESTI20004890, TESTI20083940, TESTI20168480, TESTI20239510,
TESTI20308600, TESTI20478010, UTERU20126880.
[0285] On the other hand, the clones whose expression levels were
decreased owing to the presence of Helicobacter pylori were
[0286] ASTRO20032120, BRACE20090440, BRACE20114780, BRALZ20064740,
BRAMY20002770, BRAMY20210400, BRAMY20215230, BRAMY20247280,
BRAMY20267130, BRAWH20029630, BRAWH20100690, BRAWH20118230,
BRCOC20105100, BRHIP20218580, BRSSN20046570, CTONG20138030,
CTONG20146970, CTONG20158150, D3OST20037970, FCBBF30001840,
FCBBF30033050, FEBRA20082100, HCHON20035130, HCHON20043590,
HCHON20067220, NT2NE20174920, NT2RI20009870, NT2RI20023160,
NT2RP70062230, NT2RP70130020, NTONG20070340, OCBBF20020150,
OCBBF20094240, OCBBF20107920, PROST20144220, PROST20149160,
PROST20153320, PUAEN20003740, PUAEN20025680, PUAEN20040670,
SMINT20014580, SPLEN20101190, STOMA20076800, TESTI20087620,
TESTI20098530, TESTI20123080, TESTI20161970, TESTI20234140,
TESTI20288110, TESTI20357960, TESTI20391210, TESTI20424730,
THYMU20158250, THYMU20226600, TRACH20005020, TRACH20134950,
TRACH20184490, TSTOM20001390, UTERU20119060, UTERU20134910,
UTERU20176130.
[0287] These clones are involved in gastritis or gastroduodenal
ulcer.
[0288] For example, if the polypeptide encoded by the cDNA of the
present invention is a regulatory factor of cellular conditions
such as growth and differentiation, it can be used for developing
medicines as follows. The polypeptide or antibody provided by the
invention is injected into a certain kind of cells by
microinjection. Then, using the cells, it is possible to screen low
molecular weight compounds, etc. by measuring the change in the
cellular conditions, or the activation or inhibition of a
particular gene. The screening can be performed as follows.
[0289] First, the polypeptide is expressed and purified as
recombinant. The purified polypeptide is microinjected into cells
such as various cell lines, or primary culture cells, and the
cellular change such as growth and differentiation can be examined.
Alternatively, the induction of genes whose expression is known to
be involved in a particular change of cellular conditions may be
detected by the amount of mRNA or polypeptide. Alternatively, the
amount of intracellular molecules (low molecular weight compounds,
etc.) that is changed by the function of the gene product
(polypeptide) which is known to be involved in a particular change
of cellular conditions may be detected. The compounds to be
screened (both low and high molecular compounds are acceptable) can
be added to the culture media and assessed for their activity by
measuring the change of the cellular conditions.
[0290] Instead of microinjection, cell lines introduced with the
gene obtained in the invention can be used for the screening. If
the gene product is turn out to be involved in a particular change
in the cellular conditions, the change of the product can be used
as a measurement for screening. Once a compound is screened out
which can activate or inhibit the function of the polypeptide of
the invention, it can be applied for developing medicines.
[0291] If the polypeptide encoded by the cDNA of the present
invention is a secretory protein, membrane protein, or protein
involved in signal transduction, glycoprotein, transcription, or
diseases, it can be used in functional assays for developing
medicines.
[0292] In case of a membrane protein, it is most likely to be a
polypeptide that functions as a receptor or ligand on the cell
surface. Therefore, it is possible to reveal a new relationship
between a ligand and receptor by screening the membrane protein of
the invention based on the binding activity with the known ligand
or receptor. Screening can be performed according to the known
methods.
[0293] For example, a ligand against the polypeptide of the
invention can be screened in the following manner. Namely, a ligand
that binds to a specific polypeptide can be screened by a method
comprising the steps of: (a) contacting a test sample with the
polypeptide of the invention or a partial peptide thereof, or cells
expressing these, and (b) selecting a test sample that binds to
said polypeptide, said partial peptide, or said cells.
[0294] On the other hand, for example, screening using cells
expressing the polypeptide of the present invention that is a
receptor protein can also be performed as follows. It is possible
to screen receptors that is capable of binding to a specific
polypeptide by using procedures (a) attaching the sample cells to
the polypeptide of the invention or its partial peptide, and (b)
selecting cells that can bind to the said polypeptide or its
partial peptide.
[0295] In a following screening as an example, first the
polypeptide of the invention is expressed, and the recombinant
polypeptide is purified. Next, the purified polypeptide is labeled,
binding assay is performed using a various cell lines or primary
cultured cells, and cells that are expressing a receptor are
selected (Growth and differentiation factors and their receptors,
Shin-Seikagaku Jikken Kouza Vol. 7 (1991) Honjyo, Arai, Taniguchi,
and Muramatsu edit, p203-236, Tokyo-Kagaku-Doujin). A polypeptide
of the invention can be labeled with RI such as .sup.125I, and
enzyme (alkaline phosphatase etc.).
[0296] Alternatively, a polypeptide of the invention may be used
without labeling and then detected by using a labeled antibody
against the polypeptide. The cells that are selected by the above
screening methods, which express a receptor of the polypeptide of
the invention, can be used for the further screening of an agonists
or antagonists of the said receptor.
[0297] Once the ligand binding to the polypeptide of the invention,
the receptor of the polypeptide of the invention or the cells
expressing the receptor are obtained by screening, it is possible
to screen a compound that binds to the ligand and receptor. Also it
is possible to screen a compound that can inhibit both bindings
(agonists or antagonists of the receptor, for example) by utilizing
the binding activities.
[0298] When the polypeptide of the invention is a receptor, the
screening method comprises the steps of (a) contacting the
polypeptide of the invention or cells expressing the polypeptide of
the invention with the ligand, in the presence of a test sample,
(b) detecting the binding activity between said polypeptide or
cells expressing said polypeptide and the ligand, and (c) selecting
a compound that reduces said binding activity when compared to the
activity in the absence of the test sample. Furthermore, when the
polypeptide of the invention is a ligand, the screening method
comprises the steps of (a) contacting the polypeptide of the
invention with its receptor or cells expressing the receptor in the
presence of samples, (b) detecting the binding activity between the
polypeptide and its receptor or the cells expressing the receptor,
and (c) selecting a compound that can potentially reduce the
binding activity compared to the activity in the absence of the
sample.
[0299] Samples to screen include cell extracts, expressed products
from a gene library, synthesized low molecular compound,
synthesized peptide, and natural compounds, for example, but are
not construed to be listed here. A compound that is isolated by the
above screening using a binding activity of the polypeptide of the
invention can also be used as a sample.
[0300] A compound isolated by the screening may be a candidate to
be an agonist or an antagonist of the receptor of the polypeptide.
By utilizing an assay that monitors a change in the intracellular
signaling such as phosphorylation which results from reduction of
the binding between the polypeptide and its receptor, it is
possible to identify whether the obtained compound is an agonist or
antagonist of the receptor. Also, the compound may be a candidate
of a molecule that can inhibit the interaction between the
polypeptide and its associated proteins (including a receptor) in
vivo. Such compounds can be used for developing drugs for
precaution or cures of a disease in which the polypeptide is
involved.
[0301] Secretory proteins may regulate cellular conditions such as
growth and differentiation. It is possible to find out a novel
factor that regulates cellular conditions by adding the secretory
protein of the invention to a certain kind of cell, and performing
a screening by utilizing the cellular changes in growth or
differentiation, or activation of a particular gene.
[0302] The screening can be performed, for example, as follows.
First, the polypeptide of the invention is expressed and purified
in a recombinant form. Then, the purified polypeptide is added to a
various kind of cell lines or primary cultured cells, and the
change in the cell growth and differentiation is monitored. The
induction of a particular gene that is known to be involved in a
certain cellular change is detected by the amounts of mRNA and
polypeptide. Alternatively, the amount of an intracellular molecule
(low-molecular-weight compounds, etc.) that is changed by the
function of a gene product (polypeptide) that is known to function
in a certain cellular change is used for the detection.
[0303] Once the screening reveals that the polypeptide of the
invention can regulate cellular conditions or the functions, it is
possible to apply the polypeptide as a pharmaceutical and
diagnostic medicine for related diseases by itself or by altering a
part of it into an appropriate composition.
[0304] As is above described for membrane proteins, the secretory
protein provided by the invention may be used to explore a novel
ligand-receptor interaction using a screening based on the binding
activity to a known ligand or receptor. A similar method can be
used to identify an agonist or antagonist. The resulting compounds
obtained by the methods can be a candidate of a compound that can
inhibit the interaction between the polypeptide of the invention
and an interacting molecule (including a receptor). The compounds
may be able to use as a preventive, therapeutic, and diagnostic
medicine for the diseases, in which the polypeptide may play a
certain role.
[0305] Proteins involved in signal transduction or transcription
may be a factor that affects a certain polypeptide or gene in
response to intracellular/extracellular stimuli. It is possible to
find out a novel factor that can affect a polypeptide or gene by
expressing the polypeptide provided by the invention in a certain
types of cells, and performing a screening utilizing the activation
of a certain intracellular polypeptide or gene.
[0306] The screening may be performed as follows. First, a
transformed cell line expressing the polypeptide is obtained. Then,
the transformed cell line and the untransformed original cell line
are compared for the changes in the expression of a certain gene by
detecting the amount of its mRNA or polypeptide. Alternatively, the
amount of an intracellular molecule (low molecular weight
compounds, etc.) that is changed by the function of a certain gene
product (polypeptide) may be used for the detection. Furthermore,
the change of the expression of a certain gene can be detected by
introducing a fusion gene that comprises a regulatory region of the
gene and a marker gene (luciferase, .beta.-galactosidase, etc.)
into a cell, expressing the polypeptide provided by the invention
into the cell, and estimating the activity of a marker gene product
(polypeptide).
[0307] If the polypeptide or gene of the invention is involved in
diseases, it is possible to screen a gene or compound that can
regulate its expression and/or activity either directly or
indirectly by utilizing the polypeptide of the present
invention.
[0308] For example, the polypeptide of the invention is expressed
and purified as a recombinant polypeptide. Then, the polypeptide or
gene that interacts with the polypeptide of the invention is
purified, and screened based on the binding. Alternatively, the
screening can be performed by adding with a compound of a candidate
of the inhibitor added in advance and monitoring the change of
binding activity. In another method, a transcription regulatory
region locating in the 5'-upstream of the gene encoding the
polypeptide of the invention that is capable of regulating the
expression of other genes is obtained, and fused with a marker
gene. The fusion is introduced into a cell, and the cell is added
with compounds to explore a regulatory factor of the expression of
the said gene.
[0309] The compound obtained by the screening can be used for
developing pharmaceutical and diagnostic medicines for the diseases
in which the polypeptide of the present invention is involved.
Similarly, if the regulatory factor obtained in the screening is
turn out to be a polypeptide, compounds that can newly affect the
expression or activity of the polypeptide may be used as a medicine
for the diseases in which the polypeptide of the invention is
involved.
[0310] If the polypeptide of the invention has an enzymatic
activity, regardless as to whether it is a secretory protein,
membrane protein, or proteins involved in signal transduction,
glycoprotein, transcription, or diseases, a screening may be
performed by adding a compound to the polypeptide of the invention
and monitoring the change of the compound. The enzymatic activity
may also be utilized to screen a compound that can inhibit the
activity of the polypeptide.
[0311] In a screening given as an example, the polypeptide of the
invention is expressed and the recombinant polypeptide is purified.
Then, compounds are contacted with the purified polypeptide, and
the amount of the compound and the reaction products is examined.
Alternatively, compounds that are candidates of an inhibitor are
pretreated, then a compound (substrate) that can react with the
purified polypeptide is added, and the amount of the substrate and
the reaction products is examined.
[0312] The compounds obtained in the screening may be used as a
medicine for diseases in which the polypeptide of the invention is
involved. Also they can be applied for tests that examine whether
the polypeptide of the invention functions normally in vivo.
[0313] Whether the secretory protein, membrane protein, signal
transduction-related protein, glycoprotein-related protein, or
transcription-related protein of the present invention is a novel
protein involved in diseases or not is determined in another method
than described above, by obtaining a specific antibody against the
polypeptide of the invention, and examining the relationship
between the expression or activity of the polypeptide and a certain
disease. In an alternative way, it may be analyzed referred to the
methods in "Molecular Diagnosis of Genetic Diseases" (Elles R.
edit, (1996) in the series of "Method in Molecular Biology" (Humana
Press).
[0314] Proteins involved in diseases are targets of screening as
mentioned, and thus are very useful in developing drugs which
regulate their expression and activity. Also, the proteins are
useful in the medicinal industry as a diagnostic marker of the
related disease or a target of gene therapy.
[0315] Compounds isolated as mentioned above can be administered
patients as it is, or after formulated into a pharmaceutical
composition according to the known methods. For example, a
pharmaceutically acceptable carrier or vehicle, specifically
sterilized water, saline, plant oil, emulsifier, or suspending
agent can be mixed with the compounds appropriately. The
pharmaceutical compositions can be administered to patients by a
method known to those skilled in the art, such as intraarterial,
intravenous, or subcutaneous injections. The dosage may vary
depending on the weight or age of a patient, or the method of
administration, but those skilled in the art can choose an
appropriate dosage properly. If the compound is encoded by
polynucleotide, the polynucleotide can be cloned into a vector for
gene therapy, and used for gene therapy. The dosage of the
polynucleotide and the method of its administration may vary
depending on the weight or age of a patient, or the symptoms, but
those skilled in the art can choose properly.
[0316] The present invention further relates to databases
comprising at least a sequence of polynucleotide and/or
polypeptide, or a medium recorded in such databases, selected from
the sequence data of the nucleotide and/or the amino acids
indicated in Table 1. The term "database" means a set of
accumulated information as machine-searchable and readable
information of nucleotide sequence. The databases of the present
invention comprise at least one of the novel nucleotide sequences
of polynucleotides provided by the present invention. The databases
of the present invention can consist of only the sequence data of
the novel polynucleotides provided by the present invention or can
comprise other information on nucleotide sequences of known
full-length cDNAs or ESTs. The databases of the present invention
can be comprised of not only the information on the nucleotide
sequences but also the information on the gene functions revealed
by the present invention. Additional information such as names of
DNA clones carrying the full-length cDNAs can be recorded or linked
together with the sequence data in the databases.
[0317] The database of the present invention is useful for gaining
complete gene sequence information from partial sequence
information of a gene of interest. The database of the present
invention comprises nucleotide sequence information of full-length
cDNAs. Consequently, by comparing the information in this database
with the nucleotide sequence of a partial gene fragment yielded by
differential display method or subtraction method, the information
on the full-length nucleotide sequence of interest can be gained
from the sequence of the partial fragment as a starting clue.
[0318] The sequence information of the full-length cDNAs
constituting the database of the present invention contains not
only the information on the complete sequences but also extra
information on expression frequency of the genes as well as
homology of the genes to known genes and known polypeptides. Thus
the extra information facilitates rapid functional analyses of
partial gene fragments. Further, the information on human genes is
accumulated in the database of the present invention, and
therefore, the database is useful for isolating a human homologue
of a gene originating from other species. The human homologue can
be isolated based on the nucleotide sequence of the gene from the
original species.
[0319] At present, information on a wide variety of gene fragments
can be obtained by differential display method and subtraction
method. In general, these gene fragments are utilized as tools for
isolating the full-length sequences thereof. When the gene fragment
corresponds to an already-known gene, the full-length sequence is
easily obtained by comparing the partial sequence with the
information in known databases. However, when there exists no
information corresponding to the partial sequence of interest in
the known databases, cDNA cloning should be carried out for the
full-length cDNA. It is often difficult to obtain the full-length
nucleotide sequence using the partial sequence information as an
initial clue. If the full-length of the gene is not available, the
amino acid sequence of the polypeptide encoded by the gene remains
unidentified. Thus the database of the present invention can
contribute to the identification of full-length cDNAs corresponding
to gene fragments, which cannot be revealed by using databases of
known genes.
[0320] The present invention has provided 2443 polynucleotides. As
has not yet proceeded the isolation of full-length cDNA within the
human, the invention has great significance. It is known that
secretory proteins, membrane proteins, signal transduction-related
proteins, glycoprotein-related proteins, transcription-related
proteins, and so on are involved in many diseases. The genes and
proteins involved in diseases are useful for developing a
diagnostic marker or medicines for regulation of their expression
and activity, or as a target of gene therapy.
[0321] In particular, cDNA assumed to encode secretory proteins,
which were provided by this invention, are very important for the
industry since the encoded proteins themselves are expected to be
useful as pharmaceutical agents and many disease-related genes may
be included in them. In addition, membrane proteins, signal
transduction-related proteins, transcription-related proteins,
disease-related proteins, and genes encoding them can be used as
indicators for diseases, etc. These cDNA are also very important
for the industry, which are expected to regulate the activity or
expression of the encoded protein to treat diseases, etc.
[0322] Any patents, patent applications, and publications cited
herein are incorporated by reference.
[0323] The invention is illustrated more specifically with
reference to the following examples, but is not to be construed as
being limited thereto.
EXAMPLE 1
Preparation of cDNA Library by Oligo-Capping
(1) Extraction and Purchase of mRNA
[0324] Total RNAs as mRNA sources were extracted from human tissues
(shown below) by the method as described in the reference (J.
Sambrook, E. F. Fritsch & T. Maniatis, Molecular Cloning Second
edition, Cold Spring harbor Laboratory Press, 1989). Further, by
the method as described in the reference (J. Sambrook, E. F.
Fritsch & T. Maniatis, Molecular Cloning Second edition, Cold
Spring harbor Laboratory Press, 1989), total RNAs as mRNA sources
were extracted from human culture cells and human primary culture
cells (shown below) which had been cultivated by the methods
described in the catalogs.
[0325] The library names and the origins are indicated below in the
order of "Library name: Origin". When a library was prepared by the
subtraction method, the item is followed by a description of how to
prepare the subtracted library.
<Extraction of mRNA From Human Tissues>
NTONG: Normal tongue;
CTONG: Tongue cancer;
FCBBF: Fetal brain;
OCBBF: Fetal brain;
PLACE: Placenta;
SYNOV: Synovial membrane tissue (from rheumatioid arthritis);
CORDB: Cord blood.
<Extraction of mRNA from Culture Cells>
BNGH4: H4 cells (ATCC #HTB-148);
IMR32: IMR32 cells (ATCC #CCL-127);
SKNMC: SK-N-MC cells (ATCC #HTB-10);
3NB69: NB69 cells (RCB #RCB0480);
BGGI1: GI1 cells (RCB #RCB0763);
NB9N4: NB9 cells (RCB #RCB0477);
SKNSH: SK-N-SH cells (RCB #RCB0426);
AHMSC: Human mesenchymal (HMSC) cells;
CHONS: Chondrocytes;
ERLTF: TF-1 cells (erythroleukemia);
HELAC: HeLa cells;
JCMLC: Leukemia, myelogenous;
MESTC: Mesenchyme stem cells;
N1ESE: Mesenchymal stem cells;
NCRRM: Embryonal carcinoma;
NCRRP: Embryonal carcinoma treated with retinoic acid (RA) to
induce the differentiation;
T1ESE: Mesenchymal stem cells treated with trichostatin and
5-azacytidine to induce the differentiation;
NT2RM: NT2 cells (STARATAGENE #204101);
NT2RP: NT2 cells treated with retinoic acid (RA) for 5 weeks to
induce the differentiation;
NT2R1: NT2 cells treated with RA for 5 weeks to induce the
differentiation, followed by the treatment with the growth
inhibitor for 2 weeks;
NT2NE: NT2 cells were treated with RA and the growth inhibitor for
the neuronal differentiation, and the resultant neurons were
concentrated and harvested (NT2 Neuron);
[0326] NTISM: NT2 cells (STARATAGENE #204101) were treated with RA
for 5 weeks to induce the differentiation, and then treated with
the growth inhibitor for 2 weeks; mRNA was prepared from the cells
and a cDNA library was constructed from the mRNA; the cDNAs of the
library whose nucleotide sequences were shared by those of mRNAs
from undifferentiated NT2 cells were subtracted by using a Subtract
Kit (Invitrogen #K4320-01); the subtracted library (NT2R1-NT2RM)
was provided by this procedure.
[0327] RCB indicates that the cell was provided by the Cell Bank,
RIKEN GENE BANK, The Institute of Physical and Chemical Research;
ATCC indicates that the cell was provided by American Type Culture
Collection.
<Extraction of mRNA from Primary Culture Cells>
ASTRO: Normal human astrocyte NHA5732, Takara Shuzo #CC2565;
DFNES: Normal human dermal fibroblast (neonatal skin); NHDF-Neo
NHDF2564, Takara Shuzo #CC2509;
MESAN: Normal human mesangial cell NHMC56046-2, Takara Shuzo
#CC2559;
NHNPC: Normal human neural progenitor cell NHNP5958, Takara Shuzo
#CC2599;
PEBLM: Normal human peripheral blood mononuclear cell HPBMC5939,
Takara Shuzo #CC2702;
HSYRA: Human synoviocyte HS-RA (from rheumatioid arthritis), Toyobo
#T404K-05;
PUAEN: Normal human pulmonary artery endothelial cells, Toyobo
#T302K-05;
UMVEN: Normal human umbilical vein endothelial cell HUVEC, Toyobo
#T200K-05;
HCASM: Normal human coronary artery smooth muscle cell HCASMC,
Toyobo #T305K-05;
HCHON: Normal human chondrocyte HC, Toyobo #T402K-05;
HHDPC: Normal human dermal papilla cell HDPC, Toyobo
#THPCK-001;
CD34C: CD34+ cells (AllCells, LLC #CB14435M);
D3OST: CD34+ cells treated with the osteoclast differentiation
factor (ODF) for 3 days to induce the differentiation;
D6OST: CD34+ cells treated with ODF for 6 days to induce the
differentiation;
D9OST: CD34+ cells treated with ODF for 9 days to induce the
differentiation;
ACTVT: Activated T-cells;
LYMPB: Lymphoblasts, EB virus transferred B cells;
NETRP: Neutrophils.
[0328] Then, total RNAs extracted from the following human tissues
were purchased and used as mRNA sources. The library names and the
origins are indicated below in the order of "Library name: Origin".
When a library was prepared by the subtraction method, the item is
followed by a description of how to prepare the subtracted
library.
<Purchase of Total RNA Containing mRNA Extracted From Human
Tissues>
ADRGL: Adrenal gland, CLONTECH #64016-1;
BRACE: Brain (cerebellum), CLONTECH #64035-1;
BRAWH: Whole brain, CLONTECH #64020-1;
FEBRA: Fetal brain, CLONTECH #64019-1;
FELIV: Fetal liver, CLONTECH #64018-1;
HEART: Heart, CLONTECH #64025-1;
HLUNG: Lung, CLONTECH #64023-1;
KIDNE: Kidney, CLONTECH #64030-1;
LIVER: Liver, CLONTECH #64022-1;
MAMGL: Mammary Gland, CLONTECH #64037-1;
PANCR: Pancreas, CLONTECH #64031-1;
PROST: Prostate, CLONTECH #64038-1;
SALGL: Salivary Gland, CLONTECH #64026-1;
SKMUS: Skeletal Muscle, CLONTECH #64033-1;
SMINT: Small Intestine, CLONTECH #64039-1;
SPLEN: Spleen, CLONTECH #64034-1;
STOMA: Stomach, CLONTECH #64090-1;
TBAES: Breast (Tumor), CLONTECH #64015-1;
TCERX: Cervix (Tumor), CLONTECH #64010-1;
TCOLN: Colon (Tumor), CLONTECH #64014-1;
TESTI: Testis, CLONTECH #64027-1;
THYMU: Thymus, CLONTECH #64028-1;
TLUNG: Lung (Tumor), CLONTECH #64013-1;
TOVAR: Ovary (Tumor), CLONTECH #64011-1;
TRACH: Trachea, CLONTECH #64091-1;
TUTER: Uterus (Tumor), CLONTECH #64008-1;
UTERU: Uterus, CLONTECH #64029-1;
ADIPS: Adipose, Invitrogen #D6005-01;
BLADE: Bladder, Invitrogen #D6020-01;
BRALZ: Cerebral cortex from an Alzheimer patient (Brain, cortex,
Alzheimer), Invitrogen #D6830-01;
CERVX: Cervix, Invitrogen #D6047-01;
COLON: Colon, Invitrogen #D6050-0;
NESOP: Esophagus, Invitrogen #D6060-01;
PERIC: Pericardium, Invitrogen #D6105-01;
RECTM: Rectum, Invitrogen #D6110-01;
TESOP: Esophageal (Tumor), Invitrogen #D6860-01;
TKIDN: Kidney (Tumor), Invitrogen #D6870-01;
TLIVE: Liver (Tumor), Invitrogen #D6880-01;
TSTOM: Stomach (Tumor), Invitrogen #D6920-01;
BEAST: Adult breast, STARATAGENE #735044;
FEHRT: Fetal heart, STARATAGENE #738012;
FEKID: Fetal kidney, STARATAGENE #738014;
FELNG: Fetal lung, STARATAGENE #738020;
NOVAR: Adult ovary, STARATAGENE #735260;
[0329] BRASW: subtracted library (BRALZ-BRAWH). A cDNA library was
constructed from mRNA prepared from tissues of cerebral cortex
obtained from an Alzheimer patient [BRALZ: Cerebral cortex from an
Alzheimer patient (Brain, cortex, Alzheimer), Invitrogen
#D6830-01]; the cDNAs of this library whose nucleotide sequences
were shared by those of mRNAs from whole brain tissue [BRAWH: Whole
brain, CLONTECH #64020-1] were subtracted by using a Subtract Kit
(Invitrogen #K4320-01).
[0330] Further, mRNAs extracted and purified as poly A(+) RNAs from
the human tissues shown below were purchased. A cDNA library was
prepared from an RNA mixture in which the poly A(+) RNA from each
tissue had been combined with poly A(-) RNA. The poly A(-) RNA was
prepared by removing poly A(+) RNA from the total RNA of whole
brain tissue (CLONTECH #64020-1) by using oligo dT cellulose. The
library names and the origins are indicated below in the order of
"Library name: Origin".
<Purchase of mRNAs of Human Tissues as Poly A(+) RNAs>
BRAMY: Brain (amygdala), CLONTECH #6574-1;
BRCAN: Brain (caudate nucleus), CLONTECH #6575-1;
BRCOC: Brain (corpus callosum), CLONTECH #6577-1;
BRHIP: Brain (hippocampus), CLONTECH #6578-1;
BRSSN: Brain (substantia nigra), CLONTECH #6580-1;
BRSTN: Brain (subthalamic nucleus), CLONTECH #6581-1;
BRTHA: Brain (thalamus), CLONTECH #6582-1.
(2) Preparation of cDNA Library
[0331] cDNA library was prepared from each RNA by the improved
method (WO 01/04286) of oligo capping [M. Maruyama and S. Sugano,
Gene, 138: 171-174 (1994)]. A series of procedures, BAP (Bacterial
Alkaline Phosphatase) treatment, TAP (Tobacco Acid Pyrophosphatase)
treatment, RNA ligation, first strand cDNA synthesis and RNA
removal, were carried out using the oligo-cap linker (SEQ ID NO:
5455) and oligo dT primer (SEQ ID NO: 5456), as described in WO
01/04286. Then, the single-stranded cDNA was converted to a
double-stranded cDNA by PCR (polymerase chain reaction) using 5'
(SEQ ID NO: 5457) and 3' (SEQ ID NO: 5458) PCR primers, and then
digested with SfiI. Then, a fraction of cDNA fragments, typically
2-kb or longer (3-kb or longer in some cases), was unidirectionally
cloned into a DraIII-digested pME18SFL3 vector (FIG. 1) (GenBank
AB009864, Expression vector); the cDNA library was thus
prepared.
[0332] The names of cDNA libraries, which were used in the analysis
of full-length cDNA sequences, and their origins are shown in Table
2. TABLE-US-00002 TABLE 2 Library Type Origin, etc. 3NB69 Culture
cell NB69 cells (RCB #RCB0480) ADIPS Tissue Adipose (Invitrogen
#D6005-01) ADRGL Tissue Adrenal gland (CLONTECH #64016-1) ASTRO
Primary culture cell Normal Human Astrocyte NHA5732 (Takara Shuzo
#CC2565) BEAST Tissue Adult Breast (STARATAGENE #735044) BGGI1
Culture cell GI1 cells (RCB #RCB0763) BLADE Tissue Bladder
(Invitrogen #D6020-01) BNGH4 Culture cell H4 cells (ATCC #HTB-148)
BRACE Tissue Brain, cerebellum (CLONTECH #64035-1) BRALZ Tissue
Brain, cortex, Alzheimer (Invitrogen #D6830-01) BRAMY Tissue Brain,
amygdala (CLONTECH #6574-1) BRAWH Tissue Brain, whole (CLONTECH
#64020-1) BRCAN Tissue Brain, caudate nucleus (CLONTECH #6575-1)
BRCOC Tissue Brain, corpus callosum (CLONTECH #6577-1) BRHIP Tissue
Brain, hippocampus (CLONTECH #6578-1) BRSSN Tissue Brain,
substantia nigra (CLONTECH #6580-1) BRSTN Tissue Brain, subthalamic
nucleus (CLONTECH #6581-1) BRTHA Tissue Brain, thalamus (CLONTECH
#6582-1) CD34C Primary culture cell CD34+ cells (AllCells, LLC
#CB14435M) COLON Tissue Colon (Invitrogen #D6050-0) CTONG Tissue
Tongue, Cancer D3OST Primary culture cell CD34+ cells (ODF
induction for 3 days) D6OST Primary culture cell CD34+ cells (ODF
induction for 6 days) D9OST Primary culture cell CD34+ cells (ODF
induction for 9 days) DFNES Primary culture cell Normal Human
Dermal Fibroblasts (Neonatal Skin); NHDF-Neo NHDF2564 (Takara Shuzo
#CC2509) FCBBF Tissue Brain, Fetal FEBRA Tissue Brain, Fetal
(CLONTECH #64019-1) FEHRT Tissue Heart, Fetal (STARATAGENE #738012)
FELNG Tissue Lung, Fetal (STARATAGENE #738020) HCASM Primary
culture cell Human coronary artery smooth muscle cells HCASMC
(Toyobo #T305K-05) HCHON Primary culture cell Human Chondrocytes HC
(Toyobo #T402K-05) HEART Tissue Heart (CLONTECH #64025-1) HHDPC
Primary culture cell Human dermal papilla cells HDPC (Toyobo
#THPCK- 001) HLUNG Tissue Lung (CLONTECH #64023-1) IMR32 Culture
cell IMR32 cells (ATCC #CCL-127) KIDNE Tissue Kidney (CLONTECH
#64030-1) LIVER Tissue Liver (CLONTECH #64022-1) MAMGL Tissue
Mammary Gland (CLONTECH #64037-1) MESAN Primary culture cell Normal
human mesangial cells NHMC56046-2 (Takara Shuzo #CC2559) NESOP
Tissue Esophagus (Invitrogen #D6060-01) NOVAR Tissue Adult Ovary
(STARATAGENE #735260) NT2NE Culture cell NT2 cells concentrated
after differenciation (NT2 Neuron) NT2RI Culture cell NT2 cells
treated by growth inhibitor for 2 weeks after RA induction for 5
weeks NT2RP Culture cell NT2 cells treated by RA for 5 weeks NTONG
Tissue Tongue OCBBF Tissue Brain, Fetal PANCR Tissue Pancreas
(CLONTECH #64031-1) PEBLM Primary culture cell Human peripheral
blood mononuclear cells HPBMC5939 (Takara Shuzo #CC2702) PERIC
Tissue Pericardium (Invitrogen #D6105-01) PLACE Tissue Placenta
PROST Tissue Prostate (CLONTECH #64038-1) PUAEN Primary culture
cell Human pulmonary artery endothelial cells (Toyobo #T302K-05)
RECTM Tissue Rectum (Invitrogen #D6110-01) SALGL Tissue Salivary
Gland (CLONTECH #64026-1) SKMUS Tissue Skeletal Muscle (CLONTECH
#64033-1) SKNMC Culture cell SK-N-MC cells (ATCC #HTB-10) SKNSH
Culture cell SK-N-SH cells (RCB #RCB0426) SMINT Tissue Small
Intestine (CLONTECH #64039-1) SPLEN Tissue Spleen (CLONTECH
#64034-1) STOMA Tissue Stomach (CLONTECH #64090-1) SYNOV Tissue
Synovial membrane tissue from rheumatioid arthritis TBAES Tissue
Breast, Tumor (CLONTECH #64015-1) TCOLN Tissue Colon, Tumor
(CLONTECH #64014-1) TESOP Tissue Esophageal, Tumor (Invitrogen
#D6860-01) TESTI Tissue Testis (CLONTECH #64027-1) THYMU Tissue
Thymus (CLONTECH #64028-1) TKIDN Tissue Kidney, Tumor (Invitrogen
#D6870-01) TOVAR Tissue Ovary, Tumor (CLONTECH #64011-1) TRACH
Tissue Trachea (CLONTECH #64091-1) TSTOM Tissue Stomach, Tumor
(Invitrogen #D6920-01) TUTER Tissue Uterus, Tumor (CLONTECH
#64008-1) UMVEN Primary culture cell Human umbilical vein
endothelial cells HUVEC (Toyobo #T200K-05) UTERU Tissue Uterus
(CLONTECH #64029-1)
[0333] The cDNA library with the high fullness ratio (the fullness
ratio of 5'-end, which was calculated for each cDNA library by
using the protein coding region found in known mRNA species as an
index, was 90% in average) prepared by the improved oligo-capping
method was constructed by using a eukaryotic expression vector
pME18SFL3. The vector contains SR .alpha. promoter and SV40 small t
intron in the upstream of the cloning site, and SV40 polyA added
signal sequence site in the downstream. As the cloning site of
pME18SFL3 has asymmetrical DraIII sites, and the ends of cDNA
fragments contain SfiI sites complementary to the DraIII sites, the
cloned cDNA fragments can be inserted into the downstream of the SR
.alpha. promoter unidirectionally. Therefore, clones containing
full-length cDNA can be expressed transiently by introducing the
obtained plasmid directly into COS cells, etc. Thus, the clones can
be analyzed very easily in terms of the proteins that are the gene
products of the clones, or in terms of the biological activities of
the proteins.
(3) Assessment of the 5'-end Completeness of Clones Derived from
the cDNA Library Prepared by Oligo-Capping
[0334] With respect to the plasmid DNAs of clones derived from the
libraries, the nucleotide sequences of cDNA 5'-ends (3'-ends as
well in some cases) were determined in a DNA sequencer (ABI PRISM
3700, PE Biosystems), after sequencing reaction was conducted by
using a DNA sequencing reagent (BigDye Terminator Cycle Sequencing
FS Ready Reaction Kit, PE Biosystems) according to the manual. A
database was constructed based on the obtained data.
[0335] The 5'-end completeness of about 1110,000 clones derived
from the human cDNA libraries prepared by the improved
oligo-capping method was determined by the following method. The
clones whose 5'-end sequences were consistent with those of known
human mRNA in the public database were judged to be "full-length"
if they had a longer 5'-end sequence than that of the known human
mRNA; or even though the 5'-end sequence was shorter, if it
contained the translation initiation codon it was judged to have
the "full-length" sequence. Clones which did not contain the
translation initiation codon were judged to be "not-full-length".
The fullness ratio ((the number of full-length clones)/(the number
of full-length and not-full-length clones)) at the 5'-end of the
cDNA clones was determined by comparing with known human mRNA. As a
result, the fullness ratio of the 5'-ends was 90%. The result
indicates that the fullness ratio at the 5'-end sequence was
extremely high in the human cDNA clones obtained by the
oligo-capping method.
EXAMPLE 2
Sequencing Analysis of cDNA Ends and Selection of Full-Length
Clones
[0336] With respect to the plasmid DNAs of clones obtained from
each cDNA library, the 5'-end nucleotide sequences of the cDNAs
were determined in a DNA sequencer (ABI PRISM 3700, PE Biosystems),
after sequencing reaction was conducted by using a DNA sequencing
reagent (Dye Terminator Cycle Sequencing FS Ready Reaction Kit,
dRhodamine Terminator Cycle Sequencing FS Ready Reaction Kit or
BigDye Terminator Cycle Sequencing FS Ready Reaction Kit, PE
Biosystems) according to the manual. A database was constructed
using the data obtained.
[0337] For the analyzed 5'-end sequences of cDNA clones, the data
with the annotation of "complete cds" in the GenBank and UniGene
were searched by BLAST homology search. When identical to certain
human mRNA sequences, such cDNA clones were excluded. Then,
clustering was carried out. When the identity was 90% or higher,
and the length of consensus sequence was 50 base pairs or longer,
the cDNA clones were assumed to belong to an identical cluster, and
thus clustered. cDNA clones longer in the 5' direction were
selected from the members belonging to a cluster; if required, the
3'-end sequences of the selected clones were determined by the same
analysis method as used to determine the 5'-end sequences. The data
of the end sequences obtained were analyzed, and then the clones
forming a sequence contig at 5'- and 3'-ends were excluded.
Further, as mentioned above, the data was analyzed again by BLAST
homology search; when identical to certain human mRNA sequences
(including sequences patented and applied for), the cDNA clones
were excluded. Thus, the cDNAs clones to be analyzed for their
nucleotide sequence were obtained.
EXAMPLE 3
Analysis of the Full-Length Nucleotide Sequences
[0338] The full-length nucleotide sequences of the selected clones
were determined. The nucleotide sequence determination was mainly
performed by primer walking method comprising the dideoxy
terminator method using custom-made synthetic DNA primers. Namely,
the nucleotide sequences of the DNAs were determined in a sequencer
from PE Biosystems, after sequencing reaction was carried out with
a DNA sequencing reagent from the same supplier using the
custom-made synthetic DNA primers according to the manual. A part
of the clones were analyzed with a DNA sequencer from Licor.
[0339] Further, the nucleotide sequences of a part of the clones
were determined by the shotgun method where the plasmids containing
the cDNAs were digested at random were used, instead of the use of
custom-made primers, by the same method in the DNA sequencer. The
full-length nucleotide sequences were finally determined by
completely assembling the partial nucleotide sequences obtained by
the above method.
[0340] Then, the regions translatable to proteins were deduced from
the determined full-length nucleotide sequences, and thereby the
amino acid sequences were determined. SEQ ID NOs corresponding to
the respective sequences are shown in Table 1.
EXAMPLE 4
Functional Prediction by Homology Search
[0341] For the determined nucleotide sequences, GenBank, SwissProt,
UniGene, and nr were searched by BLAST. The clones exhibiting
higher homology, which were convenient to predict their functions
based on the nucleotide sequences and deduced amino acid sequences,
were selected based on the BLAST search hit data whose P value or E
value was 10.sup.-4 or lower and for which the length of consensus
sequence.times.homology=30 or higher in the amino acid database
search. Further, from them, representative clones were selected,
which are shown as Homology Search Result Data in the last part
herein. Accordingly, the data shown herein are merely the
representative data, and the molecule exhibiting homology to each
clone is not limited thereto. Further, with respect to a part of
clones, the BLAST search hit data that did not meet the criteria as
described above are not shown herein.
EXAMPLE 5
Search for Signal Sequence, Transmembrane Domain and Other
Functional Domains in the Deduced Amino Acid Sequences
[0342] With respect to the amino acid sequences deduced from the
full-length nucleotide sequences, the prediction was made for the
presence of signal sequence at the amino terminus, the presence of
transmembrane domain, and the presence of functional protein
domains (motifs). The signal sequence at the amino terminus was
searched for by PSORT [K. Nakai & M. Kanehisa, Genomics, 14:
897-911 (1992)]; the transmembrane domain, by SOSUI [T. Hirokawa et
al., Bioinformatics, 14: 378-379 (1998)] (Mitsui Knowledge
Industry); the function domain, by Pfam
(http://www.sanger.ac.uk/Software/Pfam/index.shtml). The amino acid
sequence in which the signal sequence at the amino terminus or
transmembrane domain had been predicted to be present by PSORT or
SOSUI were assumed to be a secretory or membrane protein. Further,
when the amino acid sequence hit a certain functional domain by the
Pfam functional domain search, the protein function can be
predicted based on the hit data, for example, by referring to the
function categories on the PROSITE
(http://www.expasy.ch/cgi-bin/prosite-list.pl). In addition, the
functional domain search can also be carried out on the
PROSITE.
[0343] The search results obtained with the respective programs are
shown below.
[0344] The clones whose deduced amino acid sequences were detected
to have the signal sequences by PSORT are as follows.
[0345] ADRGL20013520, ASTRO20005330, ASTRO20055750, BNGH420088500,
BRACE20038000, BRACE20081720, BRACE20101710, BRACE20224480,
BRACE20257100, BRACE20273890, BRALZ20013500, BRALZ20054710,
BRALZ20077930, BRAMY20063970, BRAMY20284910, BRAWH20016860,
BRAWH20064050, BRCOC10000870, BRCOC20078640, BRCOC20090520,
BRCOC20101230, BRCOC20114180, BRCOC20121720, BRCOC20134480,
BRCOC20136750, BRHIP20179200, BRHIP20198190, BRHIP20217620,
BRSSN20003120, BRSSN20137020, COLON10001350, COLON20093370,
CTONG20158660, CTONG20267700, D3OST20036070, D3OST20038560,
D6OST20005070, FCBBF10001210, FCBBF10002430, FCBBF10003760,
FCBBF10005740, FCBBF20042560, FCBBF30086440, FCBBF30095260,
FCBBF30172550, FCBBF30238870, FEBRA20009090, FEBRA20029860,
FEBRA20086620, FEBRA20092890, FEBRA20111460, FEBRA20130190,
FEBRA20145780, FEBRA20235500, HCHON20064590, HCHON20067700,
HCHON20086720, HEART20049410, HHDPC20001040, HHDPC20014320,
KIDNE20011400, KIDNE20022620, KIDNE20126130, KIDNE20127450,
LIVER20064690, MESAN10001260, MESAN20038510, MESAN20115970,
MESAN20152770, MESAN20153910, NT2NE20118960, NT2NE20124480,
NT2NE20183760, NT2RI20003480, NT2RI20023910, NT2RI20028470,
NT2RI20040930, NT2RP70134990, NTONG20029700, NTONG20063010,
OCBBF20019830, OCBBF20078920, OCBBF20086400, OCBBF20087010,
OCBBF20116850, OCBBF20122620, OCBBF20130910, OCBBF20188730,
PEBLM20075980, PLACE60086400, PROST20175290, SKNSH20028660,
SMINT20009840, SMINT20022020, SMINT20073650, SMINT20095050,
SMINT20105330, SMINT20127930, SMINT20153260, SMINT20157450,
SMINT20173240, SMINT20178550, SMINT20191420, SMINT20192000,
SPLEN20079510, SPLEN20095810, SPLEN20118300, SPLEN20141360,
SPLEN20157880, SPLEN20171890, SPLEN20213830, STOMA20005390,
STOMA20056640, STOMA20080500, STOMA20088380, SYNOV20001520,
SYNOV20001730, SYNOV20002790, SYNOV20002970, SYNOV20004260,
SYNOV20007000, SYNOV20008240, SYNOV20009230, SYNOV20010880,
SYNOV20011110, SYNOV20013000, TESOP20005690, TESTI20123560,
TESTI20208400, TESTI20211220, TESTI20272960, TESTI20309170,
TESTI20316870, TESTI20385960, TESTI20390260, TESTI20391770,
TESTI20396130, TESTI20415170, TESTI20421490, TESTI20441940,
TESTI20444180, TESTI20463580, THYMU10005360, THYMU20027560,
THYMU20032870, THYMU20039810, THYMU20066100, THYMU20106710,
THYMU20111830, THYMU20161640, THYMU20162190, THYMU20194420,
THYMU20222890, THYMU20241850, TKIDN20005210, TRACH20029540,
TRACH20034840, TRACH20050040, TRACH20069180, TRACH20085400,
TRACH20136710, TRACH20145440, TRACH20180840, UTERU20158300,
UTERU20158800, UTERU20161570
[0346] The clones whose deduced amino acid sequences were detected
to have the transmembrane domains by SOSUI are as follows. Numerals
indicate the numbers of transmembrane domains detected in the
deduced amino acid sequences. Of the search result, the clone name
and the number of transmembrane domains are demarcated by a double
slash mark (//).
[0347] ADIPS10000640//3, ADRGL20018540//1, ADRGL20035850//2,
ASTRO20001410//1, ASTRO20005330//3, ASTRO20058630//4,
ASTRO20190390//1, BEAST20004540//1, BGGI110000240//2,
BRACE20006400//1, BRACE20038470//1, BRACE20039040//1,
BRACE20039540//1, BRACE20051380//1, BRACE20059370//1,
BRACE20061050//1, BRACE20063630//2, BRACE20067430//1,
BRACE20069090//2, BRACE20101700//2,
[0348] BRACE20116110//2, BRACE20147800//1, BRACE20153680//5,
BRACE20163350//1, BRACE20179340//6, BRACE20188470//4,
BRACE20195100//1, BRACE20201570//1, BRACE20210140//1,
BRACE20224480//1, BRACE20224500//1, BRACE20228480//1,
BRACE20232840//1, BRACE20238000//2, BRACE20274080//1,
BRALZ20013500//2, BRALZ20064740//1, BRALZ20069760//3,
BRALZ20073760//3, BRAMY20000860//2,
[0349] BRAMY20002770//2, BRAMY20025840//1, BRAMY20039260//3,
BRAMY20060920//1, BRAMY20063970//3, BRAMY20111960//1,
BRAMY20112800//2, BRAMY20134140//2, BRAMY20135900//1,
BRAMY20136210//1, BRAMY20144620//3, BRAMY20152110//1,
BRAMY20174550//4, BRAMY20181220//2, BRAMY20195090//1,
BRAMY20211390//1, BRAMY20211420//10, BRAMY20215230//1,
BRAMY20218250//10, BRAMY20218670//3,
[0350] BRAMY20229800//1, BRAMY20231720//1, BRAMY20247280//1,
BRAMY20252180//2, BRAMY20273960//1, BRAMY20277170//5,
BRAWH20015350//1, BRAWH20015890//2, BRAWH20016860//3,
BRAWH20018730//10, BRAWH20030250//4, BRAWH20110790//3,
BRAWH20121640//11, BRAWH20122580//2, BRAWH20132190//2,
BRCAN20064010//2, BRCAN20071190//1, BRCAN20091560//1,
BRCAN20103740//1, BRCAN20224720//1,
[0351] BRCAN20273550//5, BRCAN20280360//6, BRCAN20285450//2,
BRCOC20004040//4, BRCOC20006370//2, BRCOC20041750//1,
BRCOC20077690//2, BRCOC20090520//1, BRCOC20091960//2,
BRCOC20101230//6, BRCOC20107300//1, BRCOC20114180//3,
BRCOC20121720//7, BRCOC20134480//3, BRCOC20136750//2,
BRHIP20000870//2, BRHIP20003120//3, BRHIP20111200//1,
BRHIP20118380//1, BRHIP20118910//2,
[0352] BRHIP20121410//3, BRHIP20135100//1, BRHIP20183690//9,
BRHIP20191490//2, BRHIP20191770//1, BRHIP20207430//1,
BRHIP20208270//1, BRHIP20208590//2, BRHIP20217620//1,
BRHIP20233090//1, BRHIP20234380//1, BRHIP20238880//1,
BRHIP20283030//1, BRSSN20003120//7, BRSSN20043040//2,
BRSSN20066110//2, BRSSN20137020//2, BRSSN20142940//1,
BRSSN20146100//3, BRSSN20151990//2,
[0353] BRSSN20169050//2, BRSTN20002200//1, BRTHA20046290//2,
BRTHA20046420//5, CTONG10000100//6, CTONG10000940//1,
CTONG10001650//1, CTONG20004690//5, CTONG20092570//7,
CTONG20092580//2, CTONG20095340//5, CTONG20099380//2,
CTONG20103480//1, CTONG20105080//9, CTONG20114290//2,
CTONG20114740//3, CTONG20119200//2, CTONG20120770//1,
CTONG20124220//3, CTONG20124730//1,
[0354] CTONG20131490//1, CTONG20132220//1, CTONG20133480//2,
CTONG20139340//2, CTONG20149950//1, CTONG20155400//1,
CTONG20158660//9, CTONG20161850//2, CTONG20267700//1,
D3OST10001090//5, D3OST20036070//1, D3OST20038560//1,
D3OST30002580//2, D9OST20002780//2, D9OST20015470//2,
D9OST20026730//1, D9OST20040180//7, DFNES20025880//1,
FCBBF10000240//8, FCBBF10000380//1,
[0355] FCBBF10001150//1, FCBBF10001210//2, FCBBF10001550//1,
FCBBF10002700//2, FCBBF10003220//1, FCBBF10005460//1,
FCBBF20032970//1, FCBBF20042560//3, FCBBF20051220//2,
FCBBF30008470//2, FCBBF30012350//1, FCBBF30024750//1,
FCBBF30078290//1, FCBBF30086440//3, FCBBF30090690//1,
FCBBF30095260//2, FCBBF30123470//3, FCBBF30172550//1,
FCBBF30175310//9, FCBBF30190850//1,
[0356] FCBBF30215060//4, FCBBF30238870//1, FCBBF30251420//1,
FCBBF30279030//5, FEBRA20002100//5, FEBRA20037260//1,
FEBRA20080810//5, FEBRA20093520//1, FEBRA20095880//1,
FEBRA20111460//1, FEBRA20125070//1, FEBRA20130190//1,
FEBRA20140100//3, FEBRA20145780//2, FEBRA20211710//1,
FEBRA20229630//3, FEBRA20235500//10, HCHON20000380//2,
HCHON20007510//1, HCHON20008180//1,
[0357] HCHON20016650//7, HCHON20035130//1, HCHON20040020//1,
HCHON20067700//1, HCHON20068710//4, HEART20003060//1,
HEART20005410//1, HEART20034320//2, HEART20049800//1,
HEART20072310//2, HHDPC10000830//3, HHDPC20001040//1,
HHDPC20014320//1, HHDPC20034720//1, HHDPC20068620//1,
HHDPC20084140//1, HHDPC20091780//2, HLUNG10000550//2,
KIDNE20003940//10, KIDNE20007770//2,
[0358] KIDNE20021910//4, KIDNE20022620//1, KIDNE20100070//2,
KIDNE20101510//2, KIDNE20109730//2, KIDNE20121880//5,
KIDNE20125630//2, KIDNE20126010//1, KIDNE20130450//2,
KIDNE20131580//7, KIDNE20137340//4, KIDNE20181660//1,
LIVER20035110//1, LIVER20045650//1, LIVER20062510//1,
LIVER20075680//1, LIVER20087060//1, LIVER20091180//1,
MESAN20014500//6, MESAN20027090//2,
[0359] MESAN20038510//1, MESAN20089360//1, MESAN20103120//5,
MESAN20115970//4, MESAN20139360//1, MESAN20153910//1,
NOVAR20000380//1, NT2NE20010050//1, NT2NE20021620//1,
NT2NE20118960//4, NT2NE20131890//1, NT2NE20132170//9,
NT2NE20155110//1, NT2NE20156260//1, NT2NE20159740//3,
NT2NE20177520//2, NT2RI20023910//2, NT2RI20025400//2,
NT2RI20054050//8, NT2RI20076290//8,
[0360] NT2RI20086220//4, NT2RI20091940//3, NT2RI20244600//6,
NT2RP70072690//1, NT2RP70081610//6, NT2RP70122910//2,
NT2RP70125160//3, NT2RP70133740//4, NT2RP70137290//1,
NT2RP70179710//1, NT2RP70188020//1, NTONG20028070//1,
NTONG20048060//1, NTONG20049910//1, NTONG20051530//1,
NTONG20061870//1, NTONG20067830//1, NTONG20092330//2,
OCBBF10001750//2, OCBBF20013890//3,
[0361] OCBBF20023570//1, OCBBF20026630//1, OCBBF20037440//1,
OCBBF20050770//1, OCBBF20059560//2, OCBBF20063320//1,
OCBBF20072320//1, OCBBF20080050//2, OCBBF20086400//1,
OCBBF20086910//1, OCBBF20088140//1, OCBBF20091150//1,
OCBBF20107090//2, OCBBF20116850//2, OCBBF20120390//12,
OCBBF20130910//2, OCBBF20132850//3, OCBBF20155060//2,
OCBBF20178880//1, OCBBF20180120//10,
[0362] OCBBF20180840//1, PANCR10000910//3, PEBLM20024320//2,
PEBLM20040150//2, PEBLM20074370//1, PERIC20004220//4,
PLACE60121080//1, PLACE60161600//2, PLACE60177140//6,
PROST20005050//1, PROST20050670//1, PROST20107820//4,
PROST20116600//2, PROST20120160//1, PROST20127800//3,
PROST20146010//3, PROST20164440//3, PROST20169800//1,
PROST20170980//1, PROST20191640//1,
[0363] PUAEN20003740//2, PUAEN20030180//2, SALGL10001710//5,
SKMUS20007800//7, SKMUS20011640//3, SKMUS20020840//3,
SKMUS20028210//1, SKMUS20028400//1, SKMUS20077400//1,
SKNSH20031740//1, SKNSH20051940//1, SKNSH20063040//3,
SMINT20011990//1, SMINT20022020//4, SMINT20029760//1,
SMINT20040860//7, SMINT20049090//1, SMINT20053870//1,
SMINT20095050//2, SMINT20100680//1,
[0364] SMINT20105330//1, SMINT20144890//1, SMINT20157450//5,
SMINT20173240//3, SMINT20178550//3, SMINT20192000//1,
SPLEN20003070//2, SPLEN20008740//4, SPLEN20026950//1,
SPLEN20029310//3, SPLEN20095810//1, SPLEN20097330//1,
SPLEN20118300//9, SPLEN20141360//1, SPLEN20141990//1,
SPLEN20144520//3, SPLEN20152760//2, SPLEN20157880//1,
SPLEN20165310//1, SPLEN20167200//1,
[0365] SPLEN20169220//2, SPLEN20169720//1, SPLEN20171890//4,
SPLEN20172120//2, SPLEN20186430//6, SPLEN20211570//2,
SPLEN20211940//3, SPLEN20213830//2, SPLEN20273950//1,
SPLEN20292950//7, SPLEN20293800//4, SPLEN20304950//2,
SPLEN20329240//1, STOMA20006780//2, STOMA20008880//1,
STOMA20051200//1, STOMA20056670//1, STOMA20062130//1,
STOMA20077450//2, STOMA20080500//4,
[0366] SYNOV20013560//1, SYNOV30001840//4, TBAES20003150//2,
TESOP20005690//3, TESTI20001720//3, TESTI20036380//6,
TESTI20037560//1, TESTI20082330//1, TESTI20094120//8,
TESTI20110280//1, TESTI20123080//1, TESTI20123560//3,
TESTI20128350//1, TESTI20136100//2, TESTI20136710//2,
TESTI20143390//8, TESTI20148000//1, TESTI20164100//3,
TESTI20193360//1, TESTI20209810//1,
[0367] TESTI20209990//1, TESTI20214250//2, TESTI20230250//1,
TESTI20231940//1, TESTI20237520//2, TESTI20242990//2,
TESTI20254220//7, TESTI20254860//1, TESTI20265970//2,
TESTI20271850//2, TESTI20272960//8, TESTI20284880//2,
TESTI20291310//4, TESTI20291960//5, TESTI20303360//1,
TESTI20303420//1, TESTI20307700//2, TESTI20316870//1,
TESTI20333000//2, TESTI20347180//6,
[0368] TESTI20347300//1, TESTI20355020//1, TESTI20357960//1,
TESTI20370810//9, TESTI20373820//1, TESTI20383880//1,
TESTI20390410//1, TESTI20391770//3, TESTI20393530//1,
TESTI20397760//2, TESTI20401280//1, TESTI20422640//2,
TESTI20441940//5, TESTI20444130//1, TESTI20449200//6,
TESTI20463520//1, TESTI20463580//1, THYMU20027560//4,
[0369] THYMU20032870//1, THYMU20039810//3, THYMU20100410//2,
THYMU20106710//1, THYMU20111830//1, THYMU20141670//1,
THYMU20147770//1, THYMU20159430//1, THYMU20161640//4,
THYMU20162190//2, THYMU20173980//2, THYMU20208300//1,
THYMU20216840//2, THYMU20229220//1, THYMU20241850//2,
THYMU20277390//7, TRACH20002870//3, TRACH20003590//1,
TRACH20016210//1, TRACH20029540//1, TRACH20033230//6,
TRACH20042920//6,
[0370] TRACH20050040//2, TRACH20068660//6, TRACH20076740//4,
TRACH20085400//2, TRACH20085830//1, TRACH20109650//2,
TRACH20111130//1, TRACH20128110//5, TRACH20134950//1,
TRACH20140820//1, TRACH20145440//1, TRACH20168350//1,
UMVEN20000690//1, UTERU20030570//5, UTERU20040610//1,
UTERU20055480//2, UTERU20076390//4, UTERU20094350//1,
UTERU20135860//2, UTERU20158300//3,
UTERU20158800//2, UTERU20161570//6, UTERU20178100//1,
UTERU20186740//1
[0371] The Names of clones whose deduced amino acid sequences were
detected to have functional domains with Pfam, and the name of hit
functional domains are as follows. The search result is indicated
as "clone name//functional domain name". When the clone has
multiple hit functional domains, they are listed and demarcated by
a double slash mark (//). When the clone has multiple hits of an
identical functional domain, each is listed without abridgment.
3NB6910001910//tRNA synthetases class II (A)// tRNA synthetases
class II (A)// DHHA1 domain
3NB6920014590//Homeobox domain
[0372] ADIPS20004250//Zinc finger, C2H2 type// DNA binding domain
with preference for// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// TRAF-type
zinc finger// Zinc finger, C2H2 type// UvrD/REP helicase// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
ADRGL10001470//Cytochrome P450//Cytochrome P450
ADRGL20011190//Calponin homology (CH) domain// Calponin homology
(CH) domain// Pou domain-N-terminal to homeobox domain
ADRGL20018300//TPR Domain// TPR Domain// TPR Domain// TPR Domain//
PPR repeat// TPR Domain
ADRGL20035850//Cytochrome P450
ADRGL20048330//PHD-finger// Rabphilin-3A effector domain// C2
domain// C2 domain
ASTRO20008010//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
ASTRO20012490//Eukaryotic initiation factor 1A
ASTRO20027430//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat
ASTRO20033160//Mitochondrial carrier proteins// Mitochondrial
carrier proteins// Mitochondrial carrier proteins
ASTRO20055750//Collagen triple helix repeat (20 copies)//
Heavy-metal-associated domain
ASTRO20058630//Vacuolar sorting protein 9 (VPS9) domain
ASTRO20064750//Zinc finger, C2H2 type// Nuclear transition protein
2
ASTRO20072210//PDZ domain (Also known as DHR or GLGF).
ASTRO20084250//KH domain// Zinc finger, C3HC4 type (RING
finger)
ASTRO20105820//FAD binding domain
ASTRO20106150//Calpain family cysteine protease// Calpain large
subunit, domain III
ASTRO20108190//Rap/ran-GAP
ASTRO20125520//DnaJ domain
ASTRO20130500//ThiF family// Repeat in ubiquitin-activating (UBA)
pro
ASTRO20143630//KH domain// Bacterial regulatory proteins, crp
family
ASTRO20155290//TPR Domain// TPR Domain// TPR Domain
[0373] ASTRO20168470//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// TRAF-type zinc finger// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
BGGI110001930//UBX domain
BGGI120006160//Fumarylacetoacetate (FAA) hydrolase fam
BLADE20003400//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
[0374] BLADE20003890//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Src homology domain 2//Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Src homology domain 2//Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
BNGH420088500//SAM domain (Sterile alpha motif)
BRACE20003070//SAM domain (Sterile alpha motif)
BRACE20011070//F-box domain.
BRACE20027620//Dienelactone hydrolase family// Dienelactone
hydrolase family
BRACE20038000//ATP synthase, Delta/Epsilon chain// Dual specificity
phosphatase, catalytic d
BRACE20039540//Immunoglobulin domain// Adenovirus E3 region protein
CR2
BRACE20050900//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
BRACE20052160//SAM domain (Sterile alpha motif)
BRACE20053280//PDZ domain (Also known as DHR or GLGF).
BRACE20053480//Ribosomal protein L22p/L17e// Glycosyl hydrolases
family 38
BRACE20053630//Plant thionins// Mitochondrial carrier proteins//
Mitochondrial carrier proteins
BRACE20057620//Eukaryotic initiation factor 4E
BRACE20058580//L1 (late) protein
BRACE20059370//FERM domain (Band 4.1 family)
BRACE20060550//Ank repeat// Ank repeat// Ank repeat// PEP-utilizing
enzymes
BRACE20060720//WD domain, G-beta repeat// WD domain, G-beta
repeat
BRACE20060890//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// TRAF-type zinc finger// Zinc finger, C2H2
type// Zinc finger, C2H2 type
BRACE20062640//Alanine racemase// RNB-like proteins
BRACE20063780//NOL1/NOP2/sun family
BRACE20064880//KH domain// KH domain// KH domain
[0375] BRACE20068590//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
BRACE20096200//Sir2 family// Sir2 family
BRACE20107530//short chain dehydrogenase
BRACE20115920//Spectrin repeat// Fes/CIP4 homology domain//
Interleukin 10
BRACE20148240//Ras family
BRACE20151320//Zinc finger, C3HC4 type (RING finger)
BRACE20153680//Sir2 family// Ion transport protein
BRACE20163350//Immunoglobulin domain// Immunoglobulin domain
BRACE20177200//RanBP1 domain.
BRACE20188470//ABC transporter// Thymidylate kinase
BRACE20190040//Integrase DNA binding domain
BRACE20192440//Translation initiation factor IF-3
BRACE20223330//3'-5' exonuclease// Adenylylsulfate kinase// Protein
of unknown function DUF82.
BRACE20232840//4Fe-4S binding domain// ABC transporter// ABC
transporter// ATPases associated with various cellular act
BRACE20240740//Ribosomal protein L36
BRACE20253330//PDZ domain (Also known as DHR or GLGF).
BRACE20269200//Heat-labile enterotoxin alpha chain
BRACE20273890//UBA domain
BRACE20284100//Polysaccharide lyase family 8
BRACE20286360//Alpha adaptin carboxyl-terminal domain
BRALZ20013500//Keratin, high sulfur B2 protein// u-PAR/Ly-6
domain
BRALZ20054710//Zinc finger, C3HC4 type (RING finger)// TRAF-type
zinc finger
BRALZ20058880//STAT protein
BRALZ20077930//Ribosomal protein S27a
BRAMY20000520//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
BRAMY20002770//DB module
BRAMY20025840//Sec7 domain
BRAMY20045240//Flagellar L-ring protein
BRAMY20054880//Pou domain-N-terminal to homeobox domain
BRAMY20103570//DNA binding domain with preference for A/T r
BRAMY20104640//Eukaryotic protein kinase domain// Protein kinase C
terminal domain
BRAMY20111960//Ribosomal protein L36
BRAMY20121620//TPR Domain// TPR Domain// TPR Domain// TPR Domain//
PPR repeat
BRAMY20124260//ZU5 domain// Death domain
BRAMY20148130//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// TBC
domain
BRAMY20153110//ACT domain// Biopterin-dependent aromatic amino acid
hydroxylase
BRAMY20157820//Kinesin motor domain
BRAMY20162510//MAGE family
BRAMY20167060//Collagen triple helix repeat (20 copies)
BRAMY20174550//ABC transporter transmembrane region.//
Phosphoribulokinase// Adenylylsulfate kinase// FtsK/SpoIIIE
family// ABC transporter
BRAMY20211390//Zinc finger, C3HC4 type (RING finger)
BRAMY20211420//Transient receptor// GGL domain
BRAMY20213100//LIM domain containing proteins// GATA zinc finger//
`Paired box` domain
BRAMY20215230//ribonuclease.
BRAMY20217460//EF hand// EF hand// EF hand
BRAMY20218250//Ion transport protein// Sir2 family// Ion transport
protein
BRAMY20240040//Nuclear transition protein 2
BRAMY20245300//Fanconi anaemia group C protein//
Metallo-beta-lactamase superfamily
BRAMY20248490//Sodium:sulfate symporter transmembrane
BRAMY20260910//Zinc finger, C2H2 type// PHD-finger// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
[0376] BRAMY20270730//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C3HC4 type (RING finger)// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
BRAMY20271400//Phorbol esters/diacylglycerol binding dom//
PHD-finger
BRAMY20277170//K+ channel tetramerisation domain//
NADH-ubiquinone/plastoquinone oxidoreduc// Ion transport protein//
Transmembrane region cyclic Nucleotide G
BRAMY20285160//NTR/C345C module
BRAWH20002320//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat
BRAWH20011710//Ank repeat// Ank repeat// Ank repeat// CAP-Gly
domain// CAP-Gly domain
BRAWH20012390//EF hand// EF hand// EF hand
BRAWH20016620//Eukaryotic protein kinase domain// EIAV coat
protein, gp90
BRAWH20018730//Sugar (and other) transporter
BRAWH20028110//4Fe-4S binding domain// LIM domain containing
proteins// LIM domain containing proteins// LIM domain containing
proteins// LIM domain containing proteins// Villin headpiece
domain
BRAWH20030250//jmjN domain
BRAWH20064050//Sushi domain (SCR repeat)// EGF-like domain//
Trypsin Inhibitor like cysteine rich domain// EGF-like domain//
Granulins// Granulins// EGF-like domain
BRAWH20075700//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Transcription factor S-II (TFIIS)// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
[0377] BRAWH20096780//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
BRAWH20101360//Hexokinase
BRAWH20103290//CRAL/TR10 domain.// Spectrin repeat// Extracellular
link domain// RhoGEF domain// PH domain
BRAWH20110960//PCI domain
BRAWH20112940//Similarity to lectin domain of ricin beta-chain, 3
copies.
BRAWH20114000//Glutamate/Leucine/Phenylalanine/Valine
dehydrogenase
BRAWH20117950//Carboxylesterases
BRAWH20118230//Transforming growth factor beta like domain
BRAWH20121640//eubacterial secY protein// Transmembrane amino acid
transporter protein
BRAWH20132190//Acetyltransferase (GNAT) family
BRAWH20137480//Villin headpiece domain
BRAWH20138660//Adaptor complexes medium subunit family
BRAWH20149340//IQ calmodulin-binding motif// RhoGEF domain
BRAWH20164460//Sigma-54 interaction domain// ATPases associated
with various cellular activities (AAA)
BRAWH20171030//Adenylate kinase// NB-ARC domain// ATPases
associated with various cellu
BRAWH20185060//Integrase core domain
BRCAN10001490//`chromo` (CHRromatin Organization MOdifier)
BRCAN20003460//Thioredoxin
BRCAN20071190//Ubiquitin family// UBX domain
BRCAN20091560//Rieske [2Fe-2S] domain// Phosphoglucose isomerase//
FAD binding domain// Pyridine nucleotide-disulphide
oxidoreductase// Phytoene dehydrogenase related enzyme
[0378] BRCAN20124080//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// WD domain, G-beta repeat// WD domain,
G-beta repeat// WD domain, G-beta repeat// WD domain, G-beta
repeat
BRCAN20273550//FATC domain
BRCAN20273640//Formin Homology 2 Domain
BRCAN20280210//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
BRCAN20280360//PAP2 superfamily
BRCOC20001860//FliP family// Glycosyl hydrolase family 47
BRCOC20004040//7 transmembrane receptor (rhodopsin family)//
Neurohypophysial hormones, C-terminal Domain
BRCOC20006370//Plexin repeat
BRCOC20008160//Spectrin repeat// Spectrin repeat// Tropomyosins//
Spectrin repeat// Adenylate cyclase// Spectrin repeat// FF domain//
Spectrin repeat// Spectrin repeat// Spectrin repeat
BRCOC20008500//Vacuolar sorting protein 9 (VPS9) domain// Ras
association (RalGDS/AF-6) domain
BRCOC20023230//Reverse transcriptase (RNA-dependent DNA
polymerase)
BRCOC20026640//Gag P30 core shell protein
BRCOC20027510//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat
BRCOC20031250//Triosephosphate isomerase
BRCOC20035130//14-3-3 proteins
BRCOC20037320//Apolipoprotein A1/A4/E family
BRCOC20055420//Helix-loop-helix DNA-binding domain//
Myristoyl-CoA
BRCOC20074760//Herpesvirus UL25 family// Beige/BEACH domain
BRCOC20110100//Integrase core domain
BRCOC20121720//PHD-finger
BRCOC20144000//Helicases conserved C-terminal domain
BRCOC20178270//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type
BRCOC20178560//LIM domain containing proteins// LIM domain
containing proteins// LIM domain containing proteins// Ribosomal
protein L24e// LIM domain containing proteins
BRHIP10001290//Ribosomal protein S3, C-terminal domai// Similarity
to lectin domain of ricin b
BRHIP20001630//Protein of unknown function DUF16
BRHIP20003120//Dehydrins// Reticulon
BRHIP20005530//ThiF family
BRHIP20096850//ICE-like protease (caspase) p20 domain//
Aminotransferases class-I
BRHIP20115080//PH domain
BRHIP20118910//Fibronectin type I domain
[0379] BRHIP20119330//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Transcription factor S-II (TFIIS)// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// TRAF-type zinc finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
BRHIP20132860//PDZ domain (Also known as DHR or GLGF).
BRHIP20143730//MYND finger
BRHIP20153600//RNA recognition motif. (a.k.a. RRM, RBD, or
BRHIP20174040//GAF domain// GAF domain// Transposase, Mutator
family//3'5'-cyclic nucleotide phosphodiesterase
BRHIP20176420//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
BRHIP20183690//DEAD/DEAH box helicase// Integral membrane protein
DUF6// Integral membrane protein DUF7
BRHIP20189980//bZIP transcription factor
BRHIP20191860//Helix-loop-helix DNA-binding domain
BRHIP20207990//Phorbol esters/diacylglycerol binding dom// Zinc
finger, C3HC4 type (RING finger)// PHD-finger
[0380] BRHIP20222280//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
BRHIP20236950//Outer Capsid protein VP4 (Hemagglutinin)
BRHIP20238600//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat
BRHIP20238880//wnt family of developmental signaling protei
BRHIP20249110//Hexokinase// Hexokinase
BRHIP20252450//Spectrin repeat// Spectrin repeat// Spectrin
repeat// Phosphoenolpyruvate carboxykinase// Spectrin repeat//
Spectrin repeat// Spectrin repeat// eRF1-like proteins// Spectrin
repeat
BRHIP20253660//SH3 domain
BRHIP20283030//Cadherin domain// Cadherin domain// Cadherin
domain// Cadherin domain// Cadherin domain// Cadherin domain//
Cadherin domain// Cadherin domain
BRHIP20285830//Intermediate filament proteins
BRHIP30004570//Sushi domain (SCR repeat)// Sushi domain (SCR
repeat)// Sushi domain (SCR repeat)// Sushi domain (SCR repeat)
BRHIP30004880//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain// Immunoglobulin domain// Fibronectin type III domain//
Fibronectin type III domain
BRSSN20003120//7 transmembrane receptor (metabotropic gluta
BRSSN20013420//Histone deacetylase family// Zn-finger in
ubiquitin-hydrolases and o
BRSSN20014260//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat
BRSSN20015790//Pyridoxal-dependent decarboxylase
BRSSN20021600//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif// Kelch motif// Kelch motif// Kelch motif
BRSSN20038200//Guanine nucleotide exchange factor for Ras-like
GTPases; N-terminal motif// Initiator RepB protein// RasGEF
domain
BRSSN20039370//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type
BRSSN20046790//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
PHD-finger// Zinc finger, C2H2 type
BRSSN20101100//`Cold-shock` DNA-binding domain
BRSSN20105870//ATPases associated with various cellular activities
(AAA)
BRSSN20117990//short chain dehydrogenase
BRSSN20120810//Trypsin
BRSSN20146100//Adenylate and Guanylate cyclase catalytic domain//
Adenylate and Guanylate cyclase catalytic domain// Zinc finger, C4
type (two domains)// Adenylate and Guanylate cyclase catalytic
domain
BRSSN20176820//Wiskott Aldrich syndrome homology region 2
BRSSN20177570//Phosducin
BRSSN20187310//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat
BRSTN10000830//Kelch motif// Kelch motif// Kelch motif// Kelch
motif
BRSTN20005360//TPR Domain// TPR Domain
BRTHA20000570//Reverse transcriptase (RNA-dependent DNA pol
BRTHA20004740//Phosphoglycerate kinases// lactate/malate
dehydrogenase// Flavoprotein// short chain dehydrogenase//
Zinc-binding dehydrogenases
BRTHA20046290//Transmembrane 4 family CD34C30004240//RhoGAP
domain
COLON10001350//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
CTONG10000220//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat
CTONG10000620//Sec7 domain// PH domain// Josephin
CTONG10000930//Armadillo/beta-catenin-like repeats
CTONG10000940//Ank repeat// Ank repeat// Ank repeat
CTONG10002770//Calponin homology (CH) domain// Calponin homology
(CH) domain
CTONG20009770//Proteasome/cyclosome repeat// Proteasome/cyclosome
repeat// Proteasome/cyclosome repeat// Proteasome/cyclosome
repeat// Proteasome/cyclosome repeat// Proteasome/cyclosome
repeat//Proteasome/cyclosome repeat
CTONG20014280//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// WD domain, G-beta repeat// WD domain,
G-beta repeat
CTONG20027090//Glypican// Leucine Rich Repeat// Leucine Rich
Repeat
[0381] CTONG20050280//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// TRAF-type
zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
CTONG20075860//Ribulose bisphosphate carboxylase, smal
CTONG20076130//Hepatitis C virus non-structural protein NS2
CTONG20085950//SCAN domain// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
CTONG20092570//Integral membrane protein DUF6//Uncharacterized
protein family UPF0005
CTONG20092700//BTB/POZ domain
CTONG20093950//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
CTONG20095340//E1-E2 ATPase
CTONG20096750//Disintegrin
CTONG20098440//Acyltransferase
CTONG20099550//GGL domain
CTONG20105080//Integral membrane protein DUF6
CTONG20106520//Pyridoxal-phosphate dependent enzyme
CTONG20114290//Apolipoprotein A1/A4/E family
[0382] CTONG20118150//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// WD domain, G-beta repeat// WD domain,
G-beta repeat// WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat
CTONG20118250//Eukaryotic-type carbonic anhydrase
[0383] CTONG20121010//Zinc finger, C2H2 type// CONSTANS family zinc
finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
CTONG20121580//Kinesin motor domain// FHA domain// Histidine
carboxylase PI chain
CTONG20124010//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat
CTONG20125640//Ribosomal protein L10//60s Acidic ribosomal
protein
CTONG20128430//Beta/Gamma crystallin// Beta/Gamma crystallin//
Beta/Gamma crystallin// Beta/Gamma crystallin// Beta/Gamma
crystallin// Similarity to lectin domain of ricin b
CTONG20129960//F-box domain.// UvrD/REP helicase// UvrD/REP
helicase// Viral (Superfamily 1) RNA helicase
CTONG20131560//PDZ domain (Also known as DHR or GLGF).
[0384] CTONG20133390//Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C3HC4
type (RING finger)// Zinc finger, C2H2 type// Zinc finger, C2H2
type
CTONG20133520//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
CTONG20139860//Ank repeat// Ank repeat// Ank repeat
CTONG20140580//Domain of unknown function DUF25//SNF2 and others
N-terminal domain// SNF2 and others N-terminal domain// Small
cytokines (intecrine/chemokine), inter
CTONG20143690//MYND finger
CTONG20146300//Reverse transcriptase (RNA-dependent DNA pol
CTONG20149460//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif// Domain of unknown function// Kelch motif// Kelch motif//
Kelch motif
CTONG20153300//C. elegans Srg family integral membrane prote// TBC
domain
CTONG20153580//F-box domain.// Leucine Rich Repeat// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich
Repeat
CTONG20155180//RNA helicase
CTONG20156780//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
CTONG20158040//UTP-glucose-1-phosphate uridylyltransferase
CTONG20158660//Latrophilin/CL-1-like GPS domain//7 transmembrane
receptor (Secretin family)
CTONG20159530//Glypican
CTONG20160560//DNA binding domain with preference for A/T rich
regions
CTONG20161850//Immunoglobulin domain
CTONG20165050//Keratin, high sulfur B2 protein
CTONG20186320//Kelch motif// Kelch motif// Kelch motif// Kelch
motif
CTONG20200310//RNB-like proteins
D3OST20006180//Dual specificity phosphatase, catalytic domain
D3OST20036070//Leucine Rich Repeat
D9OST20023970//Glycosyl hydrolases family 18//Glycosyl-hydrolases
family 18
D9OST20026730//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat
[0385] D9OST20033970//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Putative zinc finger in N-recognin// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
D9OST20035940//Mitochondrial carrier proteins// Mitochondrial
carrier proteins
D9OST20040180//7 transmembrane receptor (rhodopsin family)
DFNES20037420//Elongation factor Tu family
DFNES20071130//Phosphotriesterase family// Phosphotriesterase
family// Phosphotriesterase family
FCBBF10000240//Phosphoenolpyruvate carboxylase// Bacterial
Cytochrome Ubiquinol Oxidas// Glycosyl transferase
FCBBF10000630//Molluscan rhodopsin C-terminal tail// WW domain
FCBBF10001150//Cadherin domain// Cadherin domain// Cadherin
domain// Cadherin domain// Cadherin domain
FCBBF10001210//Immunoglobulin domain// Immunoglobulin domain
FCBBF10001550//Glutamate/Leucine/Phenylalanine/Valine
dehydrogenase
[0386] FCBBF10001710//DM DNA binding domain// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
FCBBF10002800//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
FCBBF10003670//Ubiquitin carboxyl-terminal hydrolases famil
[0387] FCBBF10003770//PDZ domain (Also known as DHR or GLGF).// PDZ
domain (Also known as DHR or GLGF).// pf kB family carbohydrate
kinase// PDZ domain (Also known as DHR or GLGF).// ThiC family//
PDZ domain (Also known as DHR or GLGF).// PDZ domain (Also known as
DHR or GLGF).// PDZ domain (Also known as DHR or GLGF).// TIR
domain
FCBBF10004120//RNA recognition motif. (a.k.a. RRM, RBD, or
[0388] FCBBF10004370//KRAB box// Zinc finger, C2H2 type// Ribosomal
protein L37e// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
FCBBF10005060//CRAL/TRIO domain.
FCBBF10005460//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Fibronectin type III domain// Fibronectin
type III domain
FCBBF10005500//Keratin, high sulfur B2 protein
FCBBF10005740//Mitochondrial carrier proteins// Mitochondrial
carrier proteins
FCBBF20014270//Acyl CoA binding protein
FCBBF20042170//Fibrillar collagen C-terminal domain
FCBBF20049300//Olfactomedin-like domain
FCBBF20059090//Zinc finger, C2H2 type
FCBBF20064520//RNA recognition motif. (a.k.a. RRM, RBD, or
FCBBF20067810//Nerve growth factor family// GTP1/OBG family//
GTP1/OBG family// GTPase of unknown function// ADP-ribosylation
factor family// Ras family
FCBBF20068820//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
[0389] FCBBF30010810//KRAB box// Rieske [2Fe-2S] domain// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
FCBBF30012350//Eukaryotic protein kinase domain
FCBBF30012810//Ubiquitin carboxyl-terminal hydrolases famil
FCBBF30015940//Methyl-accepting chemotaxis protein (MCP) signaling
domain
FCBBF30016320//SecA protein, amino terminal region
FCBBF30018550//Oxysterol-binding protein
FCBBF30025560//Prolyl oligopeptidase family// Pou domain-N-terminal
to homeobox doma// Homeobox domain
FCBBF30033050//Sm protein
FCBBF30039020//Herpesvirus UL6 like// Growth-Arrest-Specific
Protein 2 Domain
[0390] FCBBF30049550//Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Glutamine amidotransferases
class-II// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// ZU5 domain
FCBBF30054440//PLAT/LH2 domain
[0391] FCBBF30057290//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
FCBBF30078290//DNA binding domain with preference for A/T r
FCBBF30086440//Pilin (bacterial filament)
FCBBF30090690//Leucine rich repeat N-terminal domain// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine rich repeat C-terminal
domain
FCBBF30095260//DHHC zinc finger domain
FCBBF30129630//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
FCBBF30175310//C1q domain// CDP-alcohol phosphatidyltransferase
FCBBF30190850//Sushi domain (SCR repeat)// Sushi domain (SCR
repeat)// Sushi domain (SCR repeat)// Keratin, high sulfur B2
protein// Sushi domain (SCR repeat)// Phosphate transporter
family
FCBBF30195640//PHD-finger// CONSTANS family zinc finger//
PHD-finger// PHD-finger// Hsp20/alpha crystallin family
FCBBF30225660//Ank repeat// Ank repeat// Ank repeat// K+ channel
tetramerisation domain// BTB/POZ domain
FCBBF30233680//G10 protein
[0392] FCBBF30238870//Laminin G domain// Thrombospondin
N-terminal-like domains// Laminin G domain// von Willebrand factor
type C domain// von Willebrand factor type C domain// EGF-like
domain// EB module// EGF-like domain// EGF-like domain// Trypsin
Inhibitor like cysteine rich domain// Metallothionein// EGF-like
domain// EGF-like domain// EGF-like domain
[0393] FCBBF30240960//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
FCBBF30246630//Leucine Rich Repeat// Leucine Rich Repeat
FCBBF30247930//Uncharacterized protein family UPF0004
FCBBF30262510//Ank repeat// Fibronectin type III domain
FCBBF30281880//Regulator of G protein signaling domain// PX
domain
FCBBF30285280//Keratin, high sulfur B2 protein// Bacterial
regulatory proteins, gntR family
FCBBF40001730//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// WD domain, G-beta repeat
FEBRA10001880//Eukaryotic protein kinase domain// Eukaryotic
protein kinase domain
FEBRA10001900//Zinc finger, C2H2 type
FEBRA20004620//Rap/ran-GAP
FEBRA20007620//Bacterial type II secretion system protein//
DEAD/DEAH box helicase// Helicases conserved C-terminal domain
FEBRA20018690//Zinc finger, C2H2 type
FEBRA20024100//Ank repeat// Ank repeat// Myosin head (motor
domain)// Myosin head (motor domain)
FEBRA20025270//Sulfotransferase proteins
[0394] FEBRA20026110//Dictyostelium (slime mold) repeats// Zinc
finger, C2H2 type// Dictyostelium (slime mold) repeats// Zinc
finger, C2H2 type// Dictyostelium (slime mold) repeats// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Dictyostelium (slime
mold) repeats// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Dictyostelium
(slime mold) repeats// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Dictyostelium (slime mold) repeats// Zinc finger, C2H2
type
[0395] FEBRA20034680//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// DnaJ central domain (4 repeats)//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type
[0396] FEBRA20040530//KRAB box// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Bacterial dnaA
protein// Zinc finger, C2H2 type// Zinc finger, C.sub.2H.sub.2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
FEBRA20080810//POT family
[0397] FEBRA20082010//KRAB box// Zinc finger, C2H2 type//
PHD-finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
FEBRA20086620//Olfactomedin-like domain
FEBRA20088360//Alpha adaptin carboxyl-terminal domai
FEBRA20090290//Zinc finger, C3HC4 type (RING finger)
FEBRA20092890//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain// Immunoglobulin domain// Fibronectin type III domain
FEBRA20097310//SAP domain// RNA recognition motif. (a.k.a. RRM,
RBD, or
FEBRA20111460//Hemagglutinin
FEBRA20130190//Galactosyltransferase// Fringe-like
FEBRA20132740//PH domain
FEBRA20144170//Eukaryotic protein kinase domain// Protein kinase C
terminal domain// Eukaryotic protein kinase domain
FEBRA20167390//Sialyltransferase family
[0398] FEBRA20171380//KRAB box// wnt family of developmental
signaling protei// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Transcription factor S-II (TFIIS)// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// PHD-finger// Zinc finger, C2H2 type// Putative zinc finger
in N-recognin// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type
FEBRA20184330//PDZ domain (Also known as DHR or GLGF).
FEBRA20192420//Cyclin-dependent kinase inhibitor// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif
FEBRA20195820//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// TRAF-type zinc finger// Zinc finger, C2H2
type
FEBRA20196370//Cyclin-dependent kinase inhibitor// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif
FEBRA20196630//DEAD/DEAH box helicase// Helicases conserved
C-terminal domain
FEBRA20214970//Reverse transcriptase (RNA-dependent DNA pol
FEBRA20222040//bZIP transcription factor// K-box region
FEBRA20223220//EGF-like domain// EGF-like domain// Cadherin
domain
FEBRA20229630//NADH-Ubiquinone/plastoquinone (complex I)
FEBRA20235500//Sodium Bile acid symporter family// ABC 3 transport
family
FEBRA20237640//SAM domain (Sterile alpha motif)
FEHRT20003250//Phosphatidylinositol 3- and 4-kinases
HCASM10000500//Ribonucleotide reductases// Nucleotidyltransferase
domain
HCHON10001760//Histone deacetylase family
HCHON20000380//Glucose-6-phosphate dehydrogenase
HCHON20003220//Formyl transferase// Phosphopantetheine attachment
site// Protein of unknown function DUF132//Aldehyde dehydrogenase
family
HCHON20007510//Phosphotyrosine interaction domain (PTB/PID)// TBC
domain
HCHON20008150//RNA recognition motif. (a.k.a. RRM, RBD, or
[0399] HCHON20008320//Glutamine synthetase// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Transcription factor S-II (TFIIS)// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type
HCHON20009560//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type
HCHON20010990//TPR Domain
HCHON20015350//FtsJ cell division protein
HCHON20015980//FG-GAP repeat// von Willebrand factor type A
domain
HCHON20016040//Insulin-like growth factor binding proteins
HCHON20016650//Leucine rich repeat C-terminal domain//
Immunoglobulin domain// Latrophilin/CL-1-like GPS domain//7
transmembrane receptor (Secretin family)
HCHON20035130//Zinc finger, C2H2 type// Zinc finger, C2H2 type
HCHON20036420//Death effector domain
HCHON20040020//Syntaxin
HCHON20059870//Bromodomain// Bromodomain
HCHON20064590//Alpha-2-macroglobulin family N-terminal regi//
Alpha-2-macroglobulin family N-terminal regi
[0400] HCHON20068410//IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif
HCHON20086720//Insulin-like growth factor binding pr//
Thyroglobulin type-1 repeat
HCHON20100740//EGF-like domain// F5/8 type C domain// F5/8 type C
domain
HEART20003060//Immunoglobulin domain// Immunoglobulin domain
HEART20005410//u-PAR/Ly-6 domain
HEART20017730//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat// Ank repeat// Ank repeat
HEART20025980//Calponin homology (CH) domain
HEART20034320//Glycosyl hydrolase family 9//Glycosyl hydrolase
family 9
HEART20061950//PDZ domain (Also known as DHR or GLGF).
HEART20077670//Protein phosphatase 2A regulatory B subunit
HEART20083640//NAD-dependent DNA ligase
HEART20090000//Inositol polyphosphate phosphatase family, c
HHDPC10000830//Zinc finger, C3HC4 type (RING finger)
HHDPC20014320//Reprolysin family propeptide
[0401] HHDPC20031130//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
HHDPC20034390//Cereal trypsin/alpha-amylase inhibito
HHDPC20034720//Glutathione S-transferases.
HHDPC20068620//Immunoglobulin domain// Immunoglobulin domain
HHDPC20091780//CUB domain// F5/8 type C domain
HHDPC20092080//Thyroglobulin type-1 repeat
HLUNG20016330//Methyl-accepting chemotaxis protein (MCP) s// PH
domain// PH domain// Methanol dehydrogenase beta subunit
HLUNG20017120//Peptidyl-tRNA hydrolase domain
HLUNG20023340//KH domain
HLUNG20033780//Birnavirus VP3 protein// RhoGEF domain// PH domain//
SH3 domain
IMR3220002430//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat
KIDNE20002520//tRNA synthetases class I (E and Q)// tRNA
synthetases class I (K)// tRNA synthetases class I (E and Q)
KIDNE20003940//Phosphotransferase system, EIIC// FecCD transport
family// ABC 3 transport family
KIDNE20007770//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain
KIDNE20008010//Dihydropyridine sensitive L-type calcium
KIDNE20009470//G-patch domain// Peptidase family M1
KIDNE20017130//MYND finger// DM DNA binding domain// Ribosomal
protein L36
KIDNE20020150//Ribosomal protein S13/S18//Hsp70 protein
KIDNE20021680//3-hydroxyacyl-CoA dehydrogenase
KIDNE20022620//Glycosyl transferase family 8
KIDNE20024830//C2 domain// C2 domain
KIDNE20027250//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type
KIDNE20027950//KRAB box
KIDNE20028390//Galactose-1-phosphate uridyl transfer//
Galactose-1-phosphate uridyl transfer
KIDNE20028720//ATP synthase (C/AC39) subunit
KIDNE20028830//K-box region
KIDNE20100070//AMP-binding enzyme
KIDNE20101510//EGF-like domain// Trypsin Inhibitor like cysteine
rich d// EGF-like domain// Keratin, high sulfur B2 protein// Zona
pellucida-like domain
KIDNE20102710//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat
KIDNE20107390//Histone-like transcription factor (CBF/// GHMP
kinases putative ATP-binding prote
KIDNE20107620//Eukaryotic protein kinase domain// Dihydropyridine
sensitive L-type calcium
KIDNE20109730//Sodium
KIDNE20109890//WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// Zinc finger, C4 type (two domains)// WD
domain, G-beta repeat// WD domain, G-beta repeat
KIDNE20121880//PMP-22/EMP/MP20/Claudin family
KIDNE20125630//ATP1G1/PLM/MAT8 family
KIDNE20127100//Kelch motif// Kelch motif// Kelch motif
KIDNE20127750//Bacterial regulatory proteins, tetR family
KIDNE20137340//Uncharacterized membrane protein family UPFO
KIDNE20182690//BAH domain// ELM2 domain
LIVER10004790//EF hand
LIVER20002160//Hsp70 protein
LIVER20035680//UvrD/REP helicase
LIVER20055440//RhoGAP domain
LIVER20064690//Serpins (serine protease inhibitors)
LIVER20080530//Ank repeat// Ank repeat// Ank repeat// SAM domain
(Sterile alpha motif)
LIVER20087060//Guanylate-binding protein
LIVER20087510//PHD-finger
MAMGL10000830//LysM domain
[0402] MESAN10001260//von Willebrand factor type C domain// von
Willebrand factor type C domain// von Willebrand factor type C
domain// von Willebrand factor type C domain// TILa domain// von
Willebrand factor type C domain// Keratin, high sulfur B2 protein//
PEP-utilizing enzymes// von Willebrand factor type D domain// Plant
PEC family metallothionein// Trypsin Inhibitor like cysteine
rich
MESAN20029400//Zinc finger, C3HC4 type (RING finger)// RNA
polymerases M/15 Kd subunits
MESAN20031900//Zinc finger, C3HC4 type (RING finger)// Peroxidase//
Zinc finger, C3HC4 type (RING finger)// B-box zinc finger.//
Fibronectin type III domain
MESAN20035290//FYVE zinc finger
MESAN20036460//Corticotropin-releasing factor family
MESAN20038510//Oxidoreductase molybdopterin binding d
MESAN20101140//LIM domain containing proteins
MESAN20103120//Sodium/calcium exchanger protein
MESAN20125860//Transferrin
MESAN20127350//Zinc knuckle
MESAN20130220//`chromo` (CHRromatin Organization MOdifier)//
Enoyl-CoA hydratase/isomerase family
MESAN20136110//KH domain// KH domain// Zinc finger, C3HC4 type
(RING finger)
MESAN20141920//Troponin// Tropomyosins// Borrelia ORF-A
MESAN20154010//Tryptophan synthase alpha chain// Ribulose-phosphate
3 epimerase family// Indole-3-glycerol phosphate synthases
MESAN20171520//PH domain
MESAN20174170//Regulator of G protein signaling domain
MESAN20186700//Hepatitis C virus RNA dependent RNA polymerase
NOVAR10000150//Cytosolic long-chain acyl-CoA thioester
hydrolase
[0403] NT2NE20010490//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type// DM
DNA binding domain// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
NT2NE20021620//Vacuolar sorting protein 9 (VPS9) domain
NT2NE20080170//CRAL/TR10 domain.
NT2NE20089970//KRAB box
[0404] NT2NE20118960//Gram-negative pili assembly chaperone
NT2NE20125050//Ezrin/radixin/moesin family
NT2NE20130190//Zinc finger, C2H2 type
NT2NE20132170//GNS1/SUR4 family// Transmembrane amino acid
transporter protein
NT2NE20142210//PAS domain// PAS domain
NT2NE20157470//von Willebrand factor type A domain// Trypsin
NT2NE20158600//Ank repeat// Ank repeat
NT2NE20177520//Sushi domain (SCR repeat)// Sushi domain (SCR
repeat)// Sushi domain (SCR repeat)// Sushi domain (SCR repeat)
NT2NE20181650//Src homology domain 2
NT2NE20183760//Calcitonin/CGRP/IAPP family
NT2NE20184900//FF domain
NT2RI20001330//Ank repeat// Ank repeat
NT2RI20003480//Glypican
NT2RI20005750//Cell division protein// Sigma-54 interaction
domain// ADP-ribosylation factor family// ABC transporter// Ras
family
NT2RI20009870//Fringe-like
NT2RI20025640//Reverse transcriptase (RNA-dependent DNA pol
NT2RI20040930//Mitochondrial carrier proteins// Mitochondrial
carrier proteins
NT2RI20040990//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat// Ank repeat// Ank repeat
NT2RI20046080//recA bacterial DNA recombination proteins
NT2RI20048840//ADP-ribosylation factor family// G-protein alpha
subunit
NT2RI20054050//HSF-type DNA-binding domain
NT2RI20056700//Spectrin repeat// Apolipoprotein A1/A4/E family//
Olfactomedin-like domain
NT2RI20091730//Molluscan rhodopsin C-terminal tail
NT2RI20240080//TPR Domain// TPR Domain// TPR Domain
NT2RI20244600//PAP2 superfamily
NT2RI20273230//DEAD/DEAH box helicase
NT2RP60000770//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
TRAF-type zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
NT2RP60000850//C2 domain
NT2RP70027380//PX domain// SH3 domain// RhoGAP domain
NT2RP70032610//Peptidase family M20/M25/M40//Enol-ase
NT2RP70036880//TBC domain
[0405] NT2RP70043480//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Transcription factor S-II (TFIIS)// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
NT2RP70044280//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
NT2RP70062230//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Pancreatic hormone peptides// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type
NT2RP70063950//RhoGEF domain// Extracellular link domain// PH
domain
NT2RP70078420//PH domain// Putative GTP-ase activating protein for
Arf// Ank repeat// Ank repeat
NT2RP70080850//SPRY domain// Adenovirus EB1 55K protein/large
t-an
NT2RP70102350//Viral methyltransferase// Helix-loop-helix
DNA-binding domain
NT2RP70105210//Myc amino-terminal region
NT2RP70157890//KRAB box
NT2RP70159960//PH domain
NT2RP70179710//Zinc finger, C3HC4 type (RING finger)//
PHD-finger
NT2RP70188710//Yeast PIR proteins
NT2RP70192730//alpha/beta hydrolase fold
NT2RP70194450//Bacterial regulatory proteins, crp family
NT2RP70195430//Zinc-binding dehydrogenases
NT2RP70198350//PWWP domain
NTONG20009770//Coronavirus S2 glycoprotein// Peptidase family
M3
NTONG20013620//Sulfotransferase proteins
NTONG20015870//Transposase// Outer membrane efflux protein//
Intermediate filament proteins
NTONG20028070//von Willebrand factor type C domain
NTONG20029480//NAD-dependent DNA ligase
NTONG20029700//Laminin N-terminal (Domain VI)// Laminin EGF-like
(Domains III and V)// Laminin EGF-like (Domains III and V)//
Laminin EGF-like (Domains III and V)
NTONG20046140//Eukaryotic protein kinase domain// Aminoglycoside
phosphotransferase
NTONG20051530//Mov34/MPN/PAD-1 family// Extracellular link domain//
Adhesin lipoprotein// Lectin C-type domain
NTONG20056570//WD domain, G-beta repeat// WD domain, G-beta
repeat
NTONG20063010//EGF-like domain// Trypsin Inhibitor like cysteine
rich domain// EGF-like domain// EGF-like domain// Keratin, high
sulfur B2 protein// Chitin binding Peritrophin-A domain// Zona
pellucida-like domain
NTONG20064840//C2 domain// C2 domain
NTONG20067830//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat
[0406] NTONG20070200//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
NTONG20070340//Collagen triple helix repeat (20 copies)// Collagen
triple helix repeat (20 copies)// Collagen triple helix repeat (20
copies)
NTONG20075220//RyR domain
NTONG20076930//Alpha-2-macroglobulin family
NTONG20083650//TPR Domain// TPR Domain// TPR Domain// PPR repeat//
TPR Domain// PPR repeat// TPR Domain
NTONG20092290//Immunoglobulin domain// Immunoglobulin domain
NTONG20092330//Putative membrane protein
[0407] OCBBF10001850//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
PHD-finger// Zinc finger, C2H2 type// DM DNA binding domain// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// MYND finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
OCBBF20019380//Sushi domain (SCR repeat)// CUB domain
OCBBF20019830//Fibronectin type III domain// Fibronectin type III
domain// EGF-like domain// Metallothionein family 5
[0408] OCBBF20020830//Pumilio-family RNA binding domains (aka
PUM-HD, Pumilio homology domain)// Pumilio-family RNA binding
domains (aka PUM-HD, Pumilio homology domain)// Pumilio-family RNA
binding domains (aka PUM-HD, Pumilio homology domain)//
Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology
domain)// Pumilio family RNA binding domains (aka PUM-HD, Pumilio
homology domain)// Putative GTP-ase activating protein for Arf//
Pumilio-family RNA binding domains (aka PUM-HD, Pumilio homology
domain)// Pumilio-family RNA binding domains (aka PUM-HD, Pumilio
homology domain)// Pumilio-family RNA binding domains (aka PUM-HD,
Pumilio homology domain)
OCBBF20022900//IQ calmodulin-binding motif// Dishevelled specific
domain// Kunitz/Bovine pancreatic trypsin inhibitor domain
OCBBF20028050//Phorbol esters/diacylglycerol binding domain (C1
domain)// Zinc finger, C3HC4 type (RING finger)// PHD-finger
OCBBF20028650//Ank repeat// Ank repeat// Helicases conserved
C-terminal domain
OCBBF20030280//Lipoprotein amino terminal region
OCBBF20035930//NSF attachment protein
OCBBF20037440//Zinc finger, C3HC4 type (RING finger)
[0409] OCBBF20046120//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// PHD-finger// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Transcription factor S-II (TFIIS)//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
[0410] OCBBF20049300//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Putative zinc finger in N-recognin// Zinc finger, C2H2
type// DM DNA binding domain// Zinc finger, C2H2 type
OCBBF20049840//PDZ domain (Also known as DHR or GLGF).
OCBBF20050770//Dehydrins// Carnitate acyltransferase
OCBBF20053430//Extracellular link domain// Eukaryotic protein
kinase domain// Protein kinase C terminal domain
OCBBF20053730//Ank repeat// Ank repeat// Ank repeat// Patatin
OCBBF20054760//Death domain
OCBBF20059560//UvrB/uvrC motif
OCBBF20066390//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
OCBBF20071210//Spectrin repeat
[0411] OCBBF20071840//Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C3HC4
type (RING finger)// Zinc finger, C2H2 type// Zinc finger, C2H2
type
OCBBF20079310//Acetyltransferase (GNAT) family
[0412] OCBBF20080410//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
OCBBF20082830//alpha/beta hydrolase fold
OCBBF20086400//ADP-ribosylation factor family// ABC transporter//
FtsK/SpoIIIE family// Ras family
OCBBF20086910//HMG (high mobility group) box
OCBBF20107090//Cadherin domain
[0413] OCBBF20108190//Zinc finger, C2H2 type// Zinc finger, C2H2
type// IBR domain// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
OCBBF20108430//ADP-ribosylation factor family// G-protein alpha
subunit
OCBBF20108580//Caspase recruitment domain
OCBBF20108630//ABC transporter
OCBBF20109310//PH domain// Arrestin (or S-antigen)
OCBBF20116850//Leucine rich repeat N-terminal domain// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine rich repeat C-terminal
domain// Immunoglobulin domain
OCBBF20120390//Caveolin// Hepatitis C virus core protein//
Sodium:neurotransmitter symporter family
OCBBF20121390//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif// Kelch motif// Kelch motif
OCBBF20124360//CNH domain
OCBBF20125530//Vpu protein// Zinc finger, C3HC4 type (RING
finger)
OCBBF20127040//Interleukin-6/G-CSF/MGF family
OCBBF20127140//WD domain, G-beta repeat// WD domain, G-beta
repeat
OCBBF20127550//Outer Capsid protein VP4 (Hemagglutinin)
OCBBF20128120//DnaJ domain// DnaJ central domain (4 repeats)// DnaJ
C terminal region
OCBBF20129360//PH domain// EF hand// Ribosomal RNA adenine
dimethylases// EF hand// Sulfotransferase proteins// Somatotropin
hormone family// Phosphatidylinositol-specific phospholi//
Phosphatidylinositol-specific phospholi// C2 domain
[0414] OCBBF20132850//Leucine rich repeat N-terminal domain//
Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat//
Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat//
Leucine Rich Repeat// Leucine rich repeat C-terminal domain//
Immunoglobulin domain// Fibronectin type III domain
OCBBF20140640//Phosphotyrosine interaction domain (PTB/PID)
OCBBF20140890//Ribosomal protein L11
OCBBF20145760//Glypican
OCBBF20148280//Zinc finger, C2H2 type// PHD-finger// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
OCBBF20148730//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif// Kelch motif
OCBBF20155060//EGF-like domain// Laminin EGF-like (Domains III and
V)// Laminin G domain// EGF-like domain// Laminin G domain//
EGF-like domain
OCBBF20173980//Regulator of chromosome condensation// Regulator of
chromosome condensation// Regulator of chromosome condensation//
Regulator of chromosome condensation// Regulator of chromosome
condensation// BTB/POZ domain// Thymidylate synthase
OCBBF20178880//Granulins
OCBBF20180120//Sodium:sulfate symporter transmembrane//
Sodium:sulfate symporter transmembrane// Sodium:sulfate symporter
transmembrane
PEBLM10000240//Domain found in Dishevelled, Eg1-10, and Ple
PEBLM20013120//PH domain
PEBLM20024320//Cation efflux family
PEBLM20042900//Chitin synthase
PEBLM20044520//Ubiquitin carboxyl-terminal hydrolase fam//
Exonuclease
PEBLM20052820//Protein phosphatase 2C
PEBLM20060310//IBR domain// Zinc finger, C3HC4 type (RING
finger)
PEBLM20060360//KRAB box
PEBLM20075980//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain
[0415] PEBLM20078320//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
PHD-finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// DnaJ central domain (4 repeats)// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
PERIC10000250//Prokaryotic DNA topoisomerase
PERIC20003870//Ribosomal L32p protein family// NAC domain// TS-N
domain
PERIC20004220//Domain of unknown function
PERIC20004780//bZIP transcription factor
PLACE60003480//Chorismate synthase
PLACE60060420//Ribosomal protein L44
[0416] PLACE60079250//Bacterial flagellin N-terminus// Spectrin
repeat// Spectrin repeat// Spectrin repeat// Caulimovirus movement
protein// Spectrin repeat// Spectrin repeat// Spectrin repeat//
UvrB/uvrC motif// Spectrin repeat// Spectrin repeat// Flagellar
hook-associated protein 2//Spectrin repeat// KE2 family protein
PLACE60136500//dUTPase
PLACE60136720//Porphobilinogen deaminase// GHMP kinases putative
ATP-binding prot
PLACE60177140//7 transmembrane receptor (rhodopsin family)
PROST20047270//CRAL/TR10 domain.
[0417] PROST20047390//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
PROST20050670//Endothelin family
PROST20066880//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
PROST20079500//Hepatitis C virus non-structural protein NS4b// Ras
association (RalGDS/AF-6) domain
PROST20100460//Cystine-knot domain
PROST20112970//Sterile alpha motif (SAM)/Pointed domain// SAM
domain (Sterile alpha motif)
PROST20114390//Integrase DNA binding domain
PROST20161950//RasGEF domain
PROST20169800//Cytochrome P450
PROST20170980//Immunoglobulin domain// Adenovirus E3 region protein
CR1
PROST20171280//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type
PROST20176170//LIM domain containing proteins// LIM domain
containing proteins// LIM domain containing proteins
PROST20185830//GATA zinc finger
[0418] PROST20189770//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Transcription factor S-II (TFIIS)//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
PROST20191640//Zinc finger, C3HC4 type (RING finger)// IBR domain//
Keratin, high sulfur B2 protein// Zinc finger, C3HC4 type (RING
finger)
PUAEN10000850//Uncharacterized protein family UPF0025//Sec1
family
PUAEN20011880//ZAP domain// Piwi domain
PUAEN20015860//PDZ domain (Also known as DHR or GLGF).// Regulator
of G protein signaling domain
PUAEN20018820//Sterile alpha motif (SAM)/Pointed domain//
Ets-domain
PUAEN20030180//Eukaryotic-type carbonic anhydrase
PUAEN20040670//FERM domain (Band 4.1 family)// FERM domain (Band
4.1 family)
PUAEN2055020//PH domain// START domain
PUAEN20078980//PH domain// FYVE zinc finger// Domain of unknown
function
DUF123//PH domain
PUAEN20083140//EF hand// PH domain// Neuregulin family
PUAEN20108240//Ank repeat// Ank repeat// Ank repeat// Ank repeat//
Ank repeat
SALGL10001710//ENV polyprotein (coat polyprotein)
SKMUS20001980//Nebulin repeat// Nebulin repeat// Nebulin repeat//
Nebulin repeat// Nebulin repeat// Nebulin repeat
SKMUS20003610//Syndecan domain// Mitochondrial carrier proteins//
Mitochondrial carrier proteins// Mitochondrial carrier proteins
SKMUS20007800//Matrix protein (MA), p15//Prenyltransferase and
squalene oxidase re
SKMUS20016220//Nebulin repeat// Nebulin repeat// Nebulin repeat//
Nebulin repeat// Nebulin repeat// Nebulin repeat// Nebulin repeat//
Nebulin repeat// Nebulin repeat
SKMUS20018230//Ank repeat
SKMUS20018500//Coronavirus S2 glycoprotein
SKMUS20024750//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat
SKMUS20029200//Ank repeat// Respiratory-chain NADH dehydrogenase,
4//Ank repeat// Ank repeat// Ank repeat// Ank repeat
SKMUS20048970//Actin// Actin
SKMUS20049030//Nebulin repeat// Nebulin repeat// Nebulin repeat//
Nebulin repeat// Nebulin repeat// Nebulin repeat
SKMUS20084740//Syndecan domain
[0419] SKNSH20008190//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// AN1-like
Zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
PHD-finger// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
SKNSH20020540//Arginase family
SKNSH20063040//Transmembrane 4 family// Transmembrane 4 family
SMINT20001760//PHD-finger// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
SMINT20009840//Immunoglobulin domain// Immunoglobulin domain
SMINT20013480//Metallo-beta-lactamase superfamily
SMINT20028820//Eukaryotic protein kinase domain
SMINT20035690//Ribosomal L29 protein
SMINT20049090//Eukaryotic protein kinase domain
SMINT20050750//Kazal-type serine protease inhibitor domain
SMINT20068010//Kinesin motor domain
SMINT20071400//NOL1/NOP2/sun family
SMINT20073650//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SMINT20102780//Quinolinate phosphoribosyl transferase
SMINT20106290//Formamidopyrimidine-DNA glycosylase
SMINT20106720//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SMINT20110330//pKID domain
SMINT20112730//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SMINT20115880//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type
SMINT20121220//Myosin tail
SMINT20121950//2Fe-2S iron-sulfur cluster binding domains
SMINT20122910//START domain
SMINT20127930//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SMINT20130320//NB-ARC domain// ATPases associated with various
cellular act
SMINT20131810//ENV polyprotein (coat polyprotein)
SMINT20136130//Immunoglobulin domain
SMINT20138900//Hr1 repeat motif// Apolipoprotein A1/A4/E family//
Intermediate filament proteins
SMINT20144430//Immunoglobulin domain
SMINT20144800//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
SMINT20152940//Sigma-54 interaction domain// ATPases associated
with various cellular activities (AAA)
SMINT20154540//Glutathione S-transferases.
SMINT20163960//Immunoglobulin domain
SMINT20168570//Fasciclin domain
SMINT20174360//haloacid dehalogenase-like hydrolase
SMINT20177360//RNA recognition motif. (a.k.a. RRM, RBD, or
SMINT20179740//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SMINT20183530//ABC transporter// ABC transporter
SMINT20190170//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SMINT20191530//DEAD/DEAH box helicase// Helicases conserved
C-terminal domain
[0420] SPLEN20006070//Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat// Ank repeat
SPLEN20008740//Importin beta binding domain//
Armadillo/beta-catenin-like repeats// Armadillo/beta-catenin-like
repeats
SPLEN20011410//RhoGAP domain
SPLEN20026950//SNF2 and others N-terminal domain// Bromodomain//
Helicases conserved C-terminal domain// Bromodomain
SPLEN20027440//Zinc finger present in dystrophin, CBP/p300//Ank
repeat// Ank repeat// Ank repeat// Ank repeat// Ank repeat// Ank
repeat// Ank repeat
SPLEN20039240//Ribosomal protein S13/S18//Hsp70 protein
[0421] SPLEN20054290//Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
SPLEN20077500//PH domain// Transposase
[0422] SPLEN20079260//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
SPLEN20084600//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif// Keich motif// Kelch motif
SPLEN20095410//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
SPLEN20095550//bZIP transcription factor// bZIP transcription
factor// Hpt domain
SPLEN20099700//Sigma-54 interaction domain// ATPases associated
with various cellular ac// Thymidine kinase from herpesvirus
SPLEN20103950//Ribosomal S17
SPLEN20118300//Transmembrane amino acid transporter protein
SPLEN20119810//Reverse transcriptase (RNA-dependent DNA
polymerase)
SPLEN20126190//Lipoate-protein ligase B
[0423] SPLEN20140800//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
PHD-finger// DnaJ central domain (4 repeats)// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
SPLEN20142100//von Willebrand factor type A domain
SPLEN20143180//Src homology domain 2
SPLEN20145720//PH domain
SPLEN20147110//HECT-domain (ubiquitin-transferase).
SPLEN20147390//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
SPLEN20149110//Dishevelled specific domain
SPLEN20150940//Histone deacetylase family
SPLEN20151210//FERM domain (Band 4.1 family)// FERM domain (Band
4.1 family)// Isocitrate lyase
SPLEN20157880//Immunoglobulin domain
SPLEN20163560//Kinesin motor domain
SPLEN20165310//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SPLEN20170310//PH domain
SPLEN20171470//Keratin, high sulfur B2 protein
SPLEN20173510//TPR Domain// TPR Domain// TPR Domain// TPR Domain//
TPR Domain// NADH-ubiquinone/plastoquinone oxidoreduct
SPLEN20174260//Penicillin amidase// Bacterial regulatory proteins,
lacI f// Vacuolar sorting protein 9 (VPS9) dom
SPLEN20179180//EF hand
SPLEN20179810//S-adenosylmethionine synthetase
SPLEN20181810//Phorbol esters/diacylglycerol binding domain (C1
domain)// FYVE zinc finger
SPLEN20186430//7 transmembrane receptor (rhodopsin family)//7
transmembrane receptor (rhodopsin family)
SPLEN20211220//Metalloenzyme superfamily
SPLEN20212730//Calpain large subunit, domain III// EF hand// EF
hand// EF hand
SPLEN20222270//PTB domain (IRS-1 type)
SPLEN20245300//Pancreatic hormone peptides
SPLEN20250170//RhoGEF domain// PH domain// FYVE zinc finger//
Domain of unknown function DUF123//PH domain
SPLEN20250390//EF hand// EF hand
[0424] SPLEN20252190//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Transcription factor S-II (TFIIS)//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// TRAF-type zinc finger// Zinc
finger, C2H2 type
SPLEN20267650//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
TRAF-type zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2
type
SPLEN20292950//Phosphoribulokinase// ABC transporter// Aldehyde
oxidase and xanthine dehydrogenase, C terminus
SPLEN20304950//Transmembrane 4 family
SPLEN20305620//Dihydroorotate dehydrogenase
STOMA20001830//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
STOMA20005390//Sodium and potassium ATPases// Immunoglobulin
domain// Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
STOMA20005670//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
STOMA20006400//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
STOMA20006780//Hepatitis C virus RNA dependent RNA polymera//
Somatotropin hormone family
STOMA20008880//Olfactomedin-like domain
STOMA20032890//Zinc finger, C2H2 type// Transcription factor S-II
(TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
STOMA20034770//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
STOMA20046680//bZIP transcription factor
STOMA20056640//Immunoglobulin domain
STOMA20056670//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
STOMA20057820//Uncharacterized protein family UPF0024
STOMA20062130//Immunoglobulin domain
STOMA20063980//Collagen triple helix repeat (20 copies)
STOMA20064470//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat
STOMA20069040//Keratin, high sulfur B2 protein
STOMA20077450//Repeat in ubiquitin-activating (UBA) pro// Repeat in
ubiquitin-activating (UBA) pro
STOMA20080500//ABC transporter STOMA20083610//Immunoglobulin
domain// Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
STOMA20088380//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
STOMA20092530//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
STOMA20092890//Myosin head (motor domain)
SYNOV20001520//Immunoglobulin domain// Immunoglobulin domain
SYNOV20001730//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20002510//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20002790//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20002970//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20004260//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20007000//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20008240//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20009230//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
SYNOV20010880//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20011110//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20013000//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20013560//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20013900//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
SYNOV20017080//UBX domain
SYNOV30001840//Asparagine synthase// AMP-binding enzyme
TBAES20000590//Cytochrome P450// Cytochrome P450
TBAES20002550//Peptidase family M1// Sigma-70 factor (ECF
subfamily)
TBAES20003150//Cytochrome P450
TESOP20004000//Papain family cysteine protease
TESOP20005270//Sulfotransferase proteins
TESTI20001000//Formamidopyrimidine-DNA glycosylase
TESTI20001170//HORMA domain
TESTI20002780//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// PEP-utilizing enzymes
TESTI20017950//Regulator of G protein signaling domain
TESTI20023510//Transcription termination factor nusG
TESTI20031810//Bacterial luciferase// Domain of unknown function
DUF28
[0425] TESTI20035960//Coproporphyrinogen III oxidase// WD domain,
G-beta repeat// WD domain, G-beta repeat// WD domain, G-beta
repeat// WD domain, G-beta repeat// WD domain, G-beta repeat// WD
domain, G-beta repeat// WD domain, G-beta repeat// WD domain,
G-beta repeat
TESTI20036380//Sulfate transporter family// Sodium Bile acid
symporter family// STAS domain
TESTI20041690//Zinc finger, C3HC4 type (RING finger)// PHD-finger//
IBR domain// Zinc finger, C3HC4 type (RING finger)// B-box zinc
finger.// lactate/malate dehydrogenase// Fibronectin type III
domain
TESTI20044230//Nucleosome assembly protein (NAP)// Nucleosome
assembly protein (NAP)// Nucleosome assembly protein (NAP)
TESTI20044310//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Chorismate synthase// UvrB/uvrC
motif
TESTI20046750//Respiratory-chain NADH dehydrogenase, 4
TESTI20057750//RNase H// Integrase Zinc binding domain
TESTI20061110//Heavy-metal-associated domain// ATPases associated
with various cellular act
TESTI20063830//Transposase
TESTI20066670//Acyl-CoA dehydrogenase
TESTI20067200//K-box region// Homeobox domain
TESTI20082330//Tudor domain
TESTI20083200//Dual specificity phosphatase, catalytic doma
TESTI20083940//Progesterone receptor
[0426] TESTI20088220//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// PHD-finger// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// BolA-like protein// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Snake toxin// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
TESTI20094470//Ets-domain
TESTI20098350//VAT-Nn domain
TESTI20108720//Protein phosphatase 2C
TESTI20121550//Putative GTP-ase activating protein for Arf
TESTI20127760//Cyclin// Calcitonin/CGRP/IAPP family
TESTI20130010//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
TESTI20136710//Glypican// PHD-finger
TESTI20143390//Integral membrane protein DUF6//Integral membrane
protein DUF6
TESTI20148000//Thioredoxin// Calsequestrin// Thioredoxin
TESTI20152460//Putative zinc finger in N-recognin// PHD-finger
TESTI20156100//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type
TESTI20157520//K+ channel tetramerisation domain// K+ channel
tetramerisation domain
TESTI20168480//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// MAM domain.// Immunoglobulin domain
TESTI20170350//Cystine-knot domain
TESTI20184620//PH domain// Oxysterol-binding protein
TESTI20185650//AN1-like Zinc finger
TESTI20189410//PHD-finger
TESTI20192800//HCO.sub.3-transporter family// Ank repeat// Ank
repeat// Ank repeat// Alpha-2-macroglobulin family
TESTI20197940//Domain of unknown function DUF27//Aconitase family
(aconitate hydratase)
TESTI20200710//PHD-finger// LIM domain containing proteins
TESTI20202650//Repeat in HS1/Cortactin
TESTI20204450//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Homeobox domain
TESTI20208400//NOL1/NOP2/sun family
TESTI20208710//WD domain, G-beta repeat// WD domain, G-beta
repeat
TESTI20211160//Hydroxyethylthiazole kinase family
TESTI20214250//Mitochondrial carrier proteins// Mitochondrial
carrier proteins
TESTI20215990//F-box domain.// Leucine Rich Repeat// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine Rich
Repeat// Leucine Rich Repeat// Leucine Rich Repeat
TESTI20216370//Carboxylesterases
TESTI20226230//Adenylate kinase// Pou domain-N-terminal to homeobox
d
TESTI20229600//EGF-like domain// Metallothionein family
5//Replication protein// Laminin G domain// EGF-like domain//
Laminin G domain// Insulin-like growth factor binding prot//
EGF-like domain// Laminin G domain
TESTI20230850//PAS domain
TESTI20231920//Gag P30 core shell protein
TESTI20232140//Phosphatidylinositol-specific phospholipase//
Phosphatidylinositol-specific phospholipase
TESTI20234140//EF hand// WD domain, G-beta repeat// WD domain,
G-beta repeat// WD domain, G-beta repeat// WD domain, G-beta
repeat
TESTI20234360//WW domain// PPIC-type PPIASE domain.
TESTI20238610//MAGE family// Uncharacterized protein family
UPF0057
TESTI20242830//E2 (early) protein, C terminal// Syndecan domain
TESTI20244190//Immunoglobulin domain// Immunoglobulin
domain//-Immunoglobulin domain// Immunoglobulin domain
TESTI20254860//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Reeler domain//
Fibronectin type III domain// Fibronectin type III domain
TESTI20255820//FERM domain (Band 4.1 family)// FERM domain (Band
4.1 family)// Isocitrate lyase
TESTI20258460//PH domain
TESTI20265970//Guanylate-binding protein
TESTI20266740//Nucleotidyltransferase domain
TESTI20272960//7 transmembrane receptor (rhodopsin family)
TESTI20275030//WD domain, G-beta repeat// WD domain, G-beta
repeat
TESTI20288910//SH3 domain
TESTI20291960//Rhomboid family
[0427] TESTI20303220//Immunoglobulin domain// Immunoglobulin
domain// Immunoglobulin domain// Immunoglobulin domain//
Fibronectin type III domain// Alphaherpesvirus glycoprotein E//
Fibronectin type III domain// Fibronectin type III domain//
Fibronectin type III domain
TESTI20303360//ENV polyprotein (coat polyprotein)
TESTI20305540//Hantavirus nucleocapsid protein// Troponin//
Apolipoprotein A1/A4/E family
TESTI20308600//Homeobox domain
TESTI20309170//TPR Domain// Zinc finger, C3HC4 type (RING finger)//
Aldo/keto reductase family// ATP-dependent protease La (LON)
domain
TESTI20314180//Trypsin// Trypsin
TESTI20317600//Terpene synthase family
TESTI20318090//Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
TESTI20320440//Thioredoxin
TESTI20320670//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)// RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
TESTI20326810//RanBP1 domain.
TESTI20327680//EF hand// EF hand
TESTI20328280//KE2 family protein// Troponin
TESTI20333000//Immunoglobulin domain// Immunoglobulin domain
TESTI20334410//DEAD/DEAH box helicase// Helicases conserved
C-terminal domain
TESTI20335050//Zinc finger, C3HC4 type (RING finger)
TESTI20335200//Immunoglobulin domain
TESTI20343070//Transcription factor E2F/dimerisation partner
(TDP)
TESTI20351830//K-box region
TESTI20352620//Saposin A-type domain
TESTI20355020//Tudor domain
TESTI20358980//Homeobox domain// Collagen triple helix repeat (20
copies)
TESTI20366910//Pyridine nucleotide-disulphide oxidoreductase
TESTI20368330//Rhodanese-like domain
TESTI20369690//PHD-finger
TESTI20370020//Bleomycin resistance protein
TESTI20370810//Ion transport protein// Polysaccharide biosynthesis
protein// Sugar (and other) transporter
TESTI20371030//Kelch motif// Kelch motif// Kelch motif// Kelch
motif// Kelch motif
TESTI20375340//Phosphatidylinositol-specific phospholi// UvrD/REP
helicase// Phosphatidylinositol-specific phospholi// C2 domain
TESTI20377230//Thymidylate synthase
[0428] TESTI20378190//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
TESTI20381040//Putative zinc finger in N-recognin
TESTI20382750//Kinesin motor domain
TESTI20383880//DnaJ domain
TESTI20385960//Zinc finger, C3HC4 type (RING finger)// SPRY
domain
TESTI20390410//Arsenical pump membrane protein
TESTI20391210//IQ calmodulin-binding motif
TESTI20391770//Domain of unknown function DUF19//Thioredoxin
TESTI20392250//PH domain// Phorbol esters/diacylglycerol binding
domain (C1 domain)
TESTI20392270//Cyclin
TESTI20392760//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat// Leucine Rich Repeat
TESTI20393530//Mitochondrial carrier proteins
TESTI20397760//E1-E2 ATPase
TESTI20400940//K-box region
TESTI20401020//Mitochondrial carrier proteins// Mitochondrial
carrier proteins
TESTI20408150//Keratin, high sulfur B2 protein
TESTI20416640//Choline/ethanolamine kinase
TESTI20432750//Cytochrome C and Quinol oxidase polypeptide
[0429] TESTI20432820//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Transcription factor
S-II (TFIIS)// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Zinc finger, C2H2 type
TESTI20436560//Spectrin repeat// Intermediate filament proteins//
Intermediate filament tail domain
TESTI20442760//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
TESTI20443090//SAP domain// Zinc knuckle// Zinc finger, C3HC4 type
(RING finger)
TESTI20444130//ENV polyprotein (coat polyprotein)
TESTI20449200//7 transmembrane receptor (metabotropic gluta
TESTI20451990//SAP domain
TESTI20455090//Intermediate filament proteins
TESTI20455620//Hsp70 protein
TESTI20456110//B-box zinc finger.// Spectrin repeat// SPRY
domain
TESTI20463580//Ubiquitin carboxyl-terminal hydrolases famil//
Immunoglobulin domain// Ubiquitin carboxyl-terminal hydrolase
family
TESTI20467320//Wiskott Aldrich syndrome homology region 2
[0430] TESTI20467970//Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain
TESTI20471410//Protein phosphatase 2C
TESTI20478850//Herpesvirus Glycoprotein B
THYMU10005360//Immunoglobulin domain// Viral coat protein//
Immunoglobulin domain
THYMU10005540//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
THYMU20023380//Copper/zinc superoxide dismutase (SODC)
THYMU20027560//Domain of unknown function
THYMU20039810//MAC/Perforin domain
THYMU20105190//Myosin head (motor domain)
THYMU20106710//Immunoglobulin domain
THYMU20111180//Domain of unknown function DUF27//Aconitase family
(aconitate hydratase)
THYMU20115850//Reverse transcriptase (RNA-dependent DNA pol
THYMU20118520//Ubiquitin family
THYMU20122730//VHS domain
THYMU20126900//3-hydroxyacyl-CoA dehydrogenase//
UDP-glucose/GDP-mannose dehydrogenase fa
THYMU20130890//Ribosomal protein S9/S16
THYMU20141670//Phorbol esters/diacylglycerol binding dom//
PHD-finger// FYVE zinc finger
THYMU20142040//Wiskott Aldrich syndrome homology region 2
THYMU20143270//Cytochrome C oxidase subunit II
THYMU20147770//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
THYMU20159430//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
THYMU20161640//PMP-22/EMP/MP20/Claudin family// Integral membrane
protein DUF6
THYMU20169680//Ank repeat// Ank repeat
THYMU20172150//WD domain, G-beta repeat
THYMU20194360//Kelch motif
THYMU20201980//PH domain// Phorbol esters/diacylglycerol binding
domain (C1 domain)// FYVE zinc finger// PH domain
THYMU20202890//Eukaryotic protein kinase domain
THYMU20209590//PH domain// Dynamin GTPase effector domain
THYMU20216840//PHD-finger
THYMU20229220//Closterovirus coat protein
THYMU20239000//Collagen triple helix repeat (20 copies)
THYMU20240710//tRNA synthetases class I (E and Q)
THYMU20241850//Class II histocompatibility antigen, beta//
Immunoglobulin domain
THYMU20247480//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type
THYMU20279750//Immunoglobulin domain
TKIDN10000010//Mitochondrial import inner membrane transloc
TKIDN20004640//GHMP kinases putative ATP-binding protei
TKIDN20047480//Eukaryotic protein kinase domain
TOVAR20004760//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat
TRACH20002870//PMP-22/EMP/MP20/Claudin family
TRACH20003590//Cytochrome P450
TRACH20005020//Ank repeat// MutT-like domain
TRACH20005400//ADP-ribosylation factor family// Ras family
TRACH20016210//Fucosyl transferase
TRACH20019960//Na+/K+ ATPase C-terminus
TRACH20028030//DnaJ domain// DnaJ central domain (4 repeats)// DnaJ
C terminal region
TRACH20033230//Nucleoside transporter// Sugar (and other)
transporter// Influenza RNA-dependent RNA polymerase subunit
PB2
TRACH20041830//Thioredoxin// Thioredoxin
TRACH20042920//Glutamine synthetase
TRACH20048450//Phospholipase D. Active site motif// Phospholipase
D. Active site motif
TRACH20050040//Plexin repeat
TRACH20067620//Core-2/1-Branching enzyme
TRACH20069180//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain
TRACH20076740//Reduced folate carrier
TRACH20076760//Keratin, high sulfur B2 protein
TRACH20077540//Zinc finger, C2H2 type// G-patch domain
TRACH20079690//KRAB box// Zinc finger, C2H2 type// Zinc finger,
C2H2 type//
TRAF-type zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type
TRACH20084720//tRNA synthetases class I (C)// tRNA synthetases
class I (I, L, M and V)
TRACH20085400//Immunoglobulin domain// Immunoglobulin domain//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain// Immunoglobulin domain
TRACH20085830//Cytochrome P450
TRACH20096610//Intermediate filament proteins// Intermediate
filament tail domain
TRACH20105870//Regulatory subunit of type II PKA R-subunit//
eIF4-gamma/eIF5/eIF2-epsilon
TRACH20121380//Raf-like Ras-binding domain// Leptin// Raf-like
Ras-binding domain// LGN motif, putative GEF specific for G-alpha
GTPase
TRACH20128230//Immunoglobulin domain// Chitin synthase//
Immunoglobulin domain// Immunoglobulin domain// Immunoglobulin
domain
TRACH20135520//TBC domain// Rhodanese-like domain
TRACH20136710//Immunoglobulin domain
TRACH20141240//Granulins
TRACH20145440//von Willebrand factor type D domain
TRACH20154860//Squash family of serine protease inhibito// Zinc
finger, C4 type (two domains)// T-box// Zinc finger, C4 type (two
domains)// Ligand-binding domain of nuclear hormone
TRACH20163170//Homeobox domain
[0431] TRACH20164980//Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// PHD-finger//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type
TRACH20167220//wnt family of developmental signaling protei//
PLAT/LH2 domain// Fibroblast growth factor
[0432] TRACH20184490//KRAB box// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type
TRACH20190240//EGF-like domain// EGF-like domain// Trypsin
Inhibitor like cysteine rich domain// EGF-like domain
TSTOM20005690//BTB/POZ domain// Kelch motif// Kelch motif// Kelch
motif
TUTER20002830//RNA recognition motif. (a.k.a. RRM, RBD, or RNP
domain)
UMVEN10001860//PH domain// RhoGAP domain// bZIP transcription
factor
UMVEN20000690//F5/8 type C domain
UTERU20030570//ABC 3 transport family// Voltage gated chloride
channels// CBS domain// CBS domain
UTERU20046640//Rotavirus NS26
UTERU20046980//EB module// TNFR/NGFR cysteine-rich region//
Furin-like cysteine rich region// Thrombospondin type 1 domain
UTERU20050690//Androgen receptor
UTERU20055330//Reverse transcriptase (RNA-dependent DNA
polymerase)
UTERU20055480//AMP-binding enzyme
UTERU20055930//Helper component proteinase
UTERU20064000//Peptidase family M1
UTERU20065930//Hr1 repeat motif// PDZ domain (Also known as DHR or
GLGF).
UTERU20115740//KRAB box
UTERU20116570//Villin headpiece domain
UTERU20119060//ADP-ribosyl cyclase
UTERU20144640//Choloylglycine hydrolase
[0433] UTERU20145480//KRAB box// Zinc finger, C2H2 type//
Transcription factor S-II (TFIIS)// Zinc finger, C2H2 type//
TRAF-type zinc finger// Zinc finger, C2H2 type// Zinc finger, C2H2
type// wnt family of developmental signaling proteins// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type// Zinc
finger, C2H2 type// Zinc finger, C2H2 type// Zinc finger, C2H2
type// Zinc finger, C2H2 type// Zinc finger, C2H2 type
UTERU20146310//Diacylglycerol kinase accessory domain (pres
UTERU20161570//7 transmembrane receptor (rhodopsin family)
UTERU20168220//Cell division protein// Integrase Zinc binding
domain// GTPase of unknown function
UTERU20176130//Putative GTP-ase activating protein for Arf
UTERU20176320//SMC domain N terminal domain// Tropomyosins
UTERU20178100//Aminotransferases class-III pyridoxal-pho
UTERU20179880//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
UTERU20183640//Immunoglobulin domain
UTERU20185230//DUP family of yeast membrane proteins
EXAMPLE 6
Functional Categorization Based on the Full-Length Nucleotide
Sequences
[0434] The functional prediction and categorization of the proteins
encoded by the clones were carried out based on the result of
homology search of the databases of GenBank, Swiss-Prot, UniGene
and nr (see the Homology Search Result Data) for the full-length
nucleotide sequences and the result of domain search of the amino
acid sequences deduced from the full-length nucleotide sequences
(see Example 5).
[0435] The clone predicted to belong to the category of secretory
protein/membrane protein means a clone having hit data with some
annotation, such as growth factor, cytokine, hormone, signal,
transmembrane, membrane, extracellular matrix, receptor, G-protein
coupled receptor, ionic channel, voltage-gated channel, calcium
channel, cell adhesion, collagen, connective tissue, etc.,
suggesting that it is a secretory or membrane protein, or means a
clone in which the presence of nucleotide sequence encoding a
signal sequence or transmembrane domain was suggested by the
results of PSORT and SOSUI analyses for deduced ORF.
[0436] The clone predicted to belong to the category of
glycoprotein-related protein means a clone having hit data with
some annotation, such as glycoprotein, suggesting that the clone
encodes a glycoprotein-related protein.
[0437] The clone predicted to belong to the category of signal
transduction-related protein means a clone having hit data with
some annotation, such as serine/threonine-protein kinase,
tyrosine-protein kinase, SH3 domain, SH2 domain, etc., suggesting
that the clone encodes a signal transduction-related protein.
[0438] The clone predicted to belong to the category of
transcription-related protein means a clone having hit data with
some annotation, such as transcription regulation, zinc finger,
homeobox, etc., suggesting that the clone encodes a
transcription-related protein.
[0439] The clone predicted to belong to the category of
disease-related protein means a clone having hit data with some
annotation, such as disease mutation, syndrome, etc., suggesting
that the clone encodes a disease-related protein, or means a clone
whose full-length nucleotide sequence has hit data for Swiss-Prot,
GenBank, or UniGene, where the hit data corresponds to genes or
proteins which have been deposited in the Online Mendelian
Inheritance in Man (OMIM) (http://www.ncbi.nlm.nih.gov/Omim/),
which is the human gene and disease database.
[0440] The clone predicted to belong to the category of enzyme
and/or metabolism-related protein means a clone having hit data
with some annotation, such as metabolism, oxidoreductase, E. C. No.
(Enzyme commission number), etc., suggesting that the clone encodes
an enzyme and/or metabolism-related protein.
[0441] The clone predicted to belong to the category of cell
division and/or cell proliferation-related protein means a clone
having hit data with some annotation, such as cell division, cell
cycle, mitosis, chromosomal protein, cell growth, apoptosis, etc.,
suggesting that the clone encodes a cell division and/or cell
proliferation-related protein.
[0442] The clone predicted to belong to the category of
cytoskeleton-related protein means a clone having hit data with
some annotation, such as structural protein, cytoskeleton,
actin-binding, microtubles, etc., suggesting that the clone encodes
a cytoskeleton-related protein.
[0443] The clone which is predicted to belong to the category of
nuclear protein and/or RNA synthesis-related protein means a clone
having hit data with some annotation, such as nuclear protein, RNA
splicing, RNA processing, RNA helicase, polyadenylation, etc.,
suggesting that the clone encodes a nuclear protein and/or RNA
synthesis-related protein.
[0444] The clone predicted to belong to the category of protein
synthesis and/or transport-related protein means a clone having hit
data with some annotation, such as translation regulation, protein
biosynthesis, amino-acid biosynthesis, ribosomal protein, protein
transport, signal recognition particle, etc., suggesting that the
clone encodes a protein synthesis and/or transport-related
protein.
[0445] The clone predicted to belong to the category of cellular
defense-related protein means a clone having hit data with some
annotation, such as heat shock, DNA repair, DNA damage, etc.,
suggesting that the clone encodes a cellular defense-related
protein.
[0446] The clone predicted to belong to the category of development
and/or differentiation-related proteins means a clone having hit
data with some annotation, such as developmental protein, etc.,
suggesting that the clone encodes a development and/or
differentiation-related protein.
[0447] The clone predicted to belong to the category of DNA-binding
and/or RNA-binding protein means a clone having hit data with some
annotation, such as DNA-binding, RNA-binding, etc.
[0448] The clone predicted to belong to the category of ATP-binding
and/or GTP-binding protein means a clone having hit data with some
annotation, such as ATP-binding, GTP-binding, etc.
[0449] In this functional categorization, when a single clone
corresponded to multiple categories of those shown above, the clone
was assigned to the multiple categories. However, the function of a
protein is not restricted to the functional category in this
classification, and there is the possibility that other functions
are newly assigned to the protein.
[0450] The clones predicted to belong to the category of secretory
protein and/or membrane protein are the following 632 clones.
[0451] ADIPS10000640, ADRGL10001470, ADRGL20013520, ADRGL20018540,
ADRGL20035850, ASTRO20001410, ASTRO20005330, ASTRO20033160,
ASTRO20055750, ASTRO20058630, ASTRO20190390, BEAST20004540,
BGGI110000240, BNGH420088500, BRACE20006400, BRACE20038000,
BRACE20038470, BRACE20039040, BRACE20039540, BRACE20051380,
BRACE20053630, BRACE20059370, BRACE20060550, BRACE20061050,
BRACE20063630, BRACE20067430, BRACE20069090, BRACE20081720,
BRACE20101700, BRACE20101710, BRACE20116110, BRACE20147800,
BRACE20153680, BRACE20163350, BRACE20179340, BRACE20188470,
BRACE20195100, BRACE20201570, BRACE20210140, BRACE20224480,
BRACE20224500, BRACE20228480, BRACE20232840, BRACE20238000,
BRACE20273890, BRACE20274080, BRALZ20013500, BRALZ20054710,
BRALZ20064740, BRALZ20069760, BRALZ20073760, BRALZ20077930,
BRAMY20000860, BRAMY20002770, BRAMY20025840, BRAMY20039260,
BRAMY20060920, BRAMY20063970, BRAMY20111960, BRAMY20112800,
BRAMY20124260, BRAMY20134140, BRAMY20135900, BRAMY20136210,
BRAMY20144620, BRAMY20152110, BRAMY20174550, BRAMY20181220,
BRAMY20195090, BRAMY20211390, BRAMY20211420, BRAMY20215230,
BRAMY20218250, BRAMY20218670, BRAMY20229800, BRAMY20231720,
BRAMY20247280, BRAMY20252180, BRAMY20273960, BRAMY20277170,
BRAMY20284910, BRAMY20285160, BRAWH20015350, BRAWH20015890,
BRAWH20016860, BRAWH20018730, BRAWH20030250, BRAWH20064050,
BRAWH20110790, BRAWH20112940, BRAWH20117950, BRAWH20118230,
BRAWH20121640, BRAWH20122580, BRAWH20132190, BRCAN20064010,
BRCAN20071190, BRCAN20091560, BRCAN20103740, BRCAN20224720,
BRCAN20273550, BRCAN20280360, BRCAN20285450, BRCOC10000870,
BRCOC20004040, BRCOC20006370, BRCOC20041750, BRCOC20077690,
BRCOC20078640, BRCOC20090520, BRCOC20101230, BRCOC20107300,
BRCOC20114180, BRCOC20121720, BRCOC20134480, BRCOC20136750,
BRHIP10001290, BRHIP20000870, BRHIP20003120, BRHIP20103090,
BRHIP20111200, BRHIP20118380, BRHIP20118910, BRHIP20121410,
BRHIP20135100, BRHIP20174040, BRHIP20179200, BRHIP20183690,
BRHIP20191490, BRHIP20191770, BRHIP20198190, BRHIP20207430,
BRHIP20208270, BRHIP20208590, BRHIP20217620, BRHIP20233090,
BRHIP20234380, BRHIP20238880, BRHIP20283030, BRHIP30004570,
BRSSN20003120, BRSSN20043040, BRSSN20066110, BRSSN20120810,
BRSSN20137020, BRSSN20142940, BRSSN20146100, BRSSN20151990,
BRSSN20169050, BRSTN20002200, BRTHA20004740, BRTHA20046290,
BRTHA20046420, COLON10001350, COLON20093370, CTONG10000100,
CTONG10000940, CTONG10001650, CTONG20004690, CTONG20009770,
CTONG20092570, CTONG20092580, CTONG20095340, CTONG20099380,
CTONG20103480, CTONG20105080, CTONG20114740, CTONG20119200,
CTONG20120770, CTONG20124730, CTONG20131490, CTONG20132220,
CTONG20133480, CTONG20139340, CTONG20149950, CTONG20155400,
CTONG20158660, CTONG20159530, CTONG20161850, CTONG20267700,
D3OST10001090, D3OST20036070, D3OST20038560, D3OST30002580,
D6OST20005070, D9OST20002780, D9OST20015470, D9OST20023970,
D9OST20026730, D9OST20035940, D9OST20040180, DFNES20025880,
FCBBF10000240, FCBBF10000380, FCBBF10001150, FCBBF10001210,
FCBBF10001550, FCBBF10002430, FCBBF10002700, FCBBF10003220,
FCBBF10003760, FCBBF10005460, FCBBF10005740, FCBBF20032970,
FCBBF20042560, FCBBF20049300, FCBBF20051220, FCBBF30008470,
FCBBF30024750, FCBBF30078290, FCBBF30083620, FCBBF30086440,
FCBBF30090690, FCBBF30095260, FCBBF30123470, FCBBF30172550,
FCBBF30175310, FCBBF30190850, FCBBF30215060, FCBBF30238870,
FCBBF30251420, FCBBF30279030, FEBRA20002100, FEBRA20004620,
FEBRA20009090, FEBRA20029860, FEBRA20037260, FEBRA20080810,
FEBRA20086620, FEBRA20092890, FEBRA20093520, FEBRA20095880,
FEBRA20111460, FEBRA20125070, FEBRA20130190, FEBRA20140100,
FEBRA20145780, FEBRA20211710, FEBRA20223220, FEBRA20229630,
FEBRA20235500, HCHON20000380, HCHON20008180, HCHON20015980,
HCHON20016040, HCHON20016650, HCHON20040020, HCHON20064590,
HCHON20067700, HCHON20068710, HCHON20086720, HCHON20100740,
HEART20003060, HEART20005410, HEART20034320, HEART20049410,
HEART20049800, HEART20072310, HHDPC20001040, HHDPC20014320,
HHDPC20034720, HHDPC20068620, HHDPC20084140, HHDPC20091780,
HHDPC20092080, HLUNG10000550, KIDNE20003940, KIDNE20007770,
KIDNE20011400, KIDNE20021910, KIDNE20022620, KIDNE20100070,
KIDNE20101510, KIDNE20109730, KIDNE20121880, KIDNE20125630,
KIDNE20126010, KIDNE20126130, KIDNE20127450, KIDNE20130450,
KIDNE20131580, KIDNE20137340, KIDNE20181660, LIVER20035110,
LIVER20045650, LIVER20055200, LIVER20062510, LIVER20064690,
LIVER20075680, LIVER20087060, LIVER20091180, MESAN10001260,
MESAN20014500, MESAN20027090, MESAN20038510, MESAN20089360,
MESAN20103120, MESAN20115970, MESAN20125860, MESAN20139360,
MESAN20152770, MESAN20153910, MESAN20174170, NOVAR20000380,
NT2NE20010050, NT2NE20021620, NT2NE20068130, NT2NE20118960,
NT2NE20124480, NT2NE20131890, NT2NE20132170, NT2NE20155110,
NT2NE20156260, NT2NE20157470, NT2NE20159740, NT2NE20177520,
NT2NE20183760, NT2RI20003480, NT2RI20023910, NT2RI20025400,
NT2RI20028470, NT2RI20040930, NT2RI20054050, NT2RI20056700,
NT2RI20076290, NT2RI20086220, NT2RI20091940, NT2RI20244600,
NT2RP70072690, NT2RP70081610, NT2RP70122910, NT2RP70125160,
NT2RP70133740, NT2RP70134990, NT2RP70137290, NT2RP70179710,
NT2RP70188020, NT2RP70192730, NT2RP70198350, NTONG20028070,
NTONG20029700, NTONG20048060, NTONG20049910, NTONG20051530,
NTONG20061870, NTONG20063010, NTONG20067830, NTONG20076930,
NTONG20092330, OCBBF10001750, OCBBF20013890, OCBBF20019830,
OCBBF20023570, OCBBF20026630, OCBBF20046690, OCBBF20050770,
OCBBF20059560, OCBBF20063320, OCBBF20071210, OCBBF20072320,
OCBBF20080050, OCBBF20086400, OCBBF20086910, OCBBF20087010,
OCBBF20088140, OCBBF20091150, OCBBF20107090, OCBBF20108630,
OCBBF20116850, OCBBF20120390, OCBBF20122620, OCBBF20130910,
OCBBF20132850, OCBBF20145760, OCBBF20155060, OCBBF20178880,
OCBBF20180120, OCBBF20180840, OCBBF20188730, PANCR10000910,
PEBLM10000710, PEBLM20024320, PEBLM20040150, PEBLM20074370,
PEBLM20075980, PERIC20004220, PLACE60086400, PLACE60121080,
PLACE60161600, PLACE60177140, PROST20005050, PROST20050670,
PROST20107820, PROST20116600, PROST20120160, PROST20127800,
PROST20146010, PROST20164440, PROST20169800, PROST20170980,
PROST20175290, PUAEN20003740, PUAEN20030180, SALGL10001710,
SKMUS20003610, SKMUS20007800, SKMUS20011640, SKMUS20020840,
SKMUS20028210, SKMUS20028400, SKMUS20077400, SKNSH20028660,
SKNSH20031740, SKNSH20051940, SKNSH20063040, SMINT20009840,
SMINT20011990, SMINT20022020, SMINT20029760, SMINT20040860,
SMINT20050750, SMINT20053870, SMINT20073650, SMINT20095050,
SMINT20100680, SMINT20105330, SMINT20106720, SMINT20121950,
SMINT20127930, SMINT20144430, SMINT201448.90, SMINT20153260,
SMINT20154540, SMINT20157450, SMINT20173240, SMINT20178550,
SMINT20191420, SMINT20192000, SPLEN20003070, SPLEN20021660,
SPLEN20029310, SPLEN20079510, SPLEN20095810, SPLEN20097330,
SPLEN20118300, SPLEN20141360, SPLEN20141990, SPLEN20142100,
SPLEN20144520, SPLEN20152760, SPLEN20157880, SPLEN20165310,
SPLEN20167200, SPLEN20169220, SPLEN20169720, SPLEN20171890,
SPLEN20172120, SPLEN20179810, SPLEN20186430, SPLEN20211570,
SPLEN20211940, SPLEN20213830, SPLEN20273950, SPLEN20292950,
SPLEN20293800, SPLEN20304950, SPLEN20329240, STOMA20005390,
STOMA20005670, STOMA20006400, STOMA20006780, STOMA20008880,
STOMA20051200, STOMA20056640, STOMA20056670, STOMA20062130,
STOMA20077450, STOMA20080500, STOMA20088380, STOMA20092530,
SYNOV20001520, SYNOV20001730, SYNOV20002510, SYNOV20002790,
SYNOV20002970, SYNOV20004260, SYNOV20007000, SYNOV20008240,
SYNOV20009230, SYNOV20010880, SYNOV20011110, SYNOV20013000,
SYNOV20013560, SYNOV20013900, SYNOV30001840, TBAES20003150,
TESOP20004000, TESOP20005690, TESTI20001720, TESTI20036380,
TESTI20037560, TESTI20094120, TESTI20110280, TESTI20123080,
TESTI20123560, TESTI20128350, TESTI20136100, TESTI20136710,
TESTI20143390, TESTI20148000, TESTI20164100, TESTI20193360,
TESTI20209810, TESTI20209990, TESTI20211220, TESTI20214250,
TESTI20216370, TESTI20230250, TESTI20231940, TESTI20242990,
TESTI20244190, TESTI20254220, TESTI20254860, TESTI20265970,
TESTI20271850, TESTI20272960, TESTI20284880, TESTI20291310,
TESTI20291960, TESTI20303220, TESTI20303360, TESTI20303420,
TESTI20307700, TESTI20309170, TESTI20314180, TESTI20316870,
TESTI20333000, TESTI20335200, TESTI20347180, TESTI20347300,
TESTI20352620, TESTI20357960, TESTI20370810, TESTI20373820,
TESTI20383880, TESTI20390260, TESTI20390410, TESTI20391770,
TESTI20393530, TESTI20396130, TESTI20397760, TESTI20401020,
TESTI20401280, TESTI20415170, TESTI20421490, TESTI20422640,
TESTI20441940, TESTI20442760, TESTI20444130, TESTI20444180,
TESTI20449200, TESTI20463520, TESTI20463580, TESTI20465350,
THYMU10005360, THYMU10005540, THYMU20027560, THYMU20032870,
THYMU20039810, THYMU20066100, THYMU20081490, THYMU20100410,
THYMU20106710, THYMU20111830, THYMU20141670, THYMU20147770,
THYMU20159430, THYMU20161640, THYMU20162190, THYMU20173980,
THYMU20194420, THYMU20208300, THYMU20216840, THYMU20222890,
THYMU20229220, THYMU20241850, THYMU20277390, TKIDN20005210,
TRACH20002870, TRACH20003590, TRACH20016210, TRACH20019960,
TRACH20029540, TRACH20033230, TRACH20034840, TRACH20042920,
TRACH20050040, TRACH20067620, TRACH20068660, TRACH20069180,
TRACH20076740, TRACH20085400, TRACH20085830, TRACH20109650,
TRACH20111130, TRACH20121380, TRACH20128110, TRACH20128230,
TRACH20134950, TRACH20136710, TRACH20139820, TRACH20140820,
TRACH20145440, TRACH20168350, TRACH20180840, TRACH20190240,
UMVEN20000690, UTERU20030570, UTERU20040610, UTERU20046980,
UTERU20055480, UTERU20064860, UTERU20076390, UTERU20094350,
UTERU20135860, UTERU20144640, UTERU20158300, UTERU20158800,
UTERU20161570, UTERU20178100, UTERU20183640, UTERU20186740
[0452] The clones predicted to belong to the category of
glycoprotein-related protein are the following 128 clones.
[0453] ADIPS10000640, BRACE20059370, BRACE20163350, BRAMY20277170,
BRAMY20285160, BRAWH20064050, BRAWH20112940, BRAWH20117950,
BRAWH20118230, BRCAN20103740, BRCOC20004040, BRCOC20006370,
BRHIP10001290, BRHIP20103090, BRHIP20283030, BRHIP30004570,
BRSSN20003120, BRSSN20146100, BRTHA20046290, COLON10001350,
CTONG20159530, D9OST20023970, D9OST20040180, FCBBF10001150,
FCBBF20049300, FCBBF30024750, FCBBF30083620, FCBBF30190850,
FCBBF30238870, FEBRA20086620, FEBRA20092890, HCHON20015980,
HCHON20016040, HCHON20064590, HCHON20086720, HCHON20100740,
HEART20003060, HHDPC20014320, HHDPC20068620, HHDPC20092080,
KIDNE20003940, KIDNE20007770, KIDNE20101510, LIVER20064690,
MESAN20125860, NT2NE20118960, NT2NE20157470, NT2NE20177520,
NT2RI20003480, NT2RI20056700, NT2RP70192730, NTONG20051530,
NTONG20076930, OCBBF20107090, OCBBF20108630, OCBBF20120390,
OCBBF20145760, OCBBF20155060, PLACE60177140, SMINT20050750,
SMINT20073650, SMINT20105330, SMINT20106720, SMINT20112730,
SMINT20127930, SMINT20153260, SMINT20179740, SMINT20190170,
SPLEN20021660, SPLEN20142100, SPLEN20157880, SPLEN20165310,
SPLEN20179810, SPLEN20186430, STOMA20001830, STOMA20005390,
STOMA20005670, STOMA20006400, STOMA20008880, STOMA20034770,
STOMA20056640, STOMA20056670, STOMA20083610, STOMA20088380,
STOMA20092530, SYNOV20001520, SYNOV20001730, SYNOV20002510,
SYNOV20002790, SYNOV20002970, SYNOV20004260, SYNOV20007000,
SYNOV20008240, SYNOV20009230, SYNOV20010880, SYNOV20011110,
SYNOV20013000, SYNOV20013560, SYNOV20013900, TESOP20004000,
TESTI20136100, TESTI20216370, TESTI20244190, TESTI20254860,
TESTI20303220, TESTI20335200, TESTI20352620, TESTI20358980,
TESTI20442760, TESTI20449200, TESTI20455090, THYMU10005360,
THYMU10005540, THYMU20147770, THYMU20159430, THYMU20241850,
TRACH20016210, TRACH20050040, TRACH20067620, TRACH20069180,
TRACH20076740, TRACH20128230, UTERU20046980, UTERU20064860,
UTERU20144640, UTERU20158800, UTERU20161570, UTERU20183640
[0454] The clones predicted to belong to the category of signal
transduction-related protein are the following 84 clones.
[0455] ASTRO20108190, BRACE20115920, BRACE20154120, BRACE20177200,
BRACE20237270, BRAMY20104640, BRAMY20242470, BRAMY20271400,
BRAWH20016620, BRAWH20103290, BRAWH20149340, BRCOC20021550,
BRCOC20091960, BRHIP20189980, BRHIP20218580, BRHIP20238600,
BRSSN20038200, CD34C30004240, CTONG20118150, CTONG20127450,
CTONG20200310, FCBBF30012350, FCBBF40001730, FEBRA10001880,
FEBRA20004620, FEBRA20132740, FEBRA20144170, FEHRT20003250,
HCHON20007510, HLUNG20033780, IMR3220002430, KIDNE20008010,
KIDNE20102710, KIDNE20107620, NT2NE20080170, NT2NE20181650,
NT2RP70027380, NT2RP70036880, NT2RP70063950, NT2RP70078420,
NT2RP70159960, NTONG20046140, NTONG20056570, OCBBF20028050,
OCBBF20053430, OCBBF20054760, OCBBF20124360, OCBBF20127140,
OCBBF20149280, OCBBF20173980, PEBLM20013120, PEBLM20085760,
PROST20161950, PUAEN20015260, PUAEN20015860, PUAEN20083140,
SMINT20028820, SMINT20049090, SMINT20110660, SPLEN20011410,
SPLEN20121750, SPLEN20170310, SPLEN20181810, SPLEN20222270,
SPLEN20250170, SPLEN20283650, TESTI20035960, TESTI20288910,
TESTI20305540, TESTI20326810, TESTI20369650, TESTI20392250,
TESTI20416640, TESTI20432750, TESTI20467320, THYMU20169680,
THYMU20172150, THYMU20201980, THYMU20202890, TKIDN20004640,
TKIDN20047480, TRACH20057690, UMVEN10001860, UTERU20146310
[0456] The clones predicted to belong to the category of
transcription-related protein are the following 144 clones.
[0457] 3NB6920014590, ADIPS20004250, ASTRO20008010, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20060890, BRACE20068590,
BRACE20257100, BRAMY20210400, BRAMY20260910, BRAMY20270730,
BRAWH20028110, BRAWH20075700, BRAWH20096780, BRCAN20280210,
BRCOC20144000, BRCOC20178270, BRHIP20005340, BRHIP20096170,
BRHIP20119330, BRHIP20191860, BRHIP20195890, BRHIP20222280,
BRSSN20039370, BRSSN20046790, BRSSN20176820, CTONG20050280,
CTONG20075860, CTONG20085950, CTONG20091080, CTONG20092700,
CTONG20121010, CTONG20124220, CTONG20133390, CTONG20133520,
D9OST20033970, FCBBF10001710, FCBBF10004370, FCBBF20059090,
FCBBF20068820, FCBBF30007680, FCBBF30010810, FCBBF30018550,
FCBBF30025560, FCBBF30057290, FCBBF30083820, FCBBF30129630,
FCBBF30240960, FCBBF30246230, FEBRA20018690, FEBRA20026110,
FEBRA20034680, FEBRA20040530, FEBRA20082010, FEBRA20171380,
FEBRA20195820, FEBRA20233770, HCHON20008320, HCHON20009560,
HCHON20035130, HHDPC10000830, HHDPC20030490, HHDPC20031130,
KIDNE20027250, KIDNE20027950, KIDNE20182690, LIVER20055440,
NT2NE20010490, NT2NE20089970, NT2NE20142210, NT2NE20184900,
NT2RP60000770, NT2RP70043480, NT2RP70063950, NT2RP70102350,
NT2RP70157890, NTONG20070200, OCBBF10001850, OCBBF20020830,
OCBBF20037440, OCBBF20046120, OCBBF20049300, OCBBF20054200,
OCBBF20066390, OCBBF20071840, OCBBF20080410, OCBBF20108190,
OCBBF20125530, OCBBF20148280, PEBLM20060360, PEBLM20078320,
PERIC20003870, PROST10003220, PROST20047390, PROST20066880,
PROST20185830, PROST20189770, PROST20191640, SKNSH20008190,
SMINT20001760, SMINT20028820, SMINT20130320, SMINT20144800,
SPLEN20026950, SPLEN20054290, SPLEN20079260, SPLEN20095410,
SPLEN20117660, SPLEN20140800, SPLEN20147390, SPLEN20160450,
SPLEN20162680, SPLEN20243830, SPLEN20250170, SPLEN20252190,
SPLEN20267650, STOMA20032890, STOMA20063250, TESTI20039400,
TESTI20041690, TESTI20067200, TESTI20088220, TESTI20130010,
TESTI20156100, TESTI20230850, TESTI20318090, TESTI20320670,
TESTI20378190, TESTI20385960, TESTI20409890, TESTI20420620,
TESTI20432820, TESTI20456110, THYMU20247480, TRACH20079690,
TRACH20154860, TRACH20163170, TRACH20164980, TRACH20184490,
UTERU20099720, UTERU20116570, UTERU20145480, UTERU20176130
[0458] The clones predicted to belong to the category of
disease-related protein are the following 387 clones.
[0459] ADIPS20004250, ADRGL10001470, ADRGL20011190, ADRGL20018300,
ADRGL20035850, ADRGL20078100, ASTRO10001650, ASTRO20008010,
ASTRO20027430, ASTRO20106150, ASTRO20108190, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20038480, BRACE20039540,
BRACE20059370, BRACE20108130, BRACE20108880, BRACE20115920,
BRACE20116460, BRACE20232840, BRACE20248260, BRACE20253330,
BRACE20284100, BRALZ20013500, BRALZ20017430, BRALZ20018340,
BRAMY20000520, BRAMY20025840, BRAMY20120910, BRAMY20134140,
BRAMY20135900, BRAMY20162510, BRAMY20174550, BRAMY20210400,
BRAMY20211390, BRAMY20242470, BRAMY20245300, BRAMY20266850,
BRAMY20285160, BRAWH20016620, BRAWH20028110, BRAWH20064050,
BRAWH20096780, BRAWH20110960, BRAWH20113430, BRAWH20114000,
BRAWH20118230, BRAWH20121640, BRAWH20128270, BRAWH20137480,
BRCAN20103740, BRCAN20224720, BRCAN20279700, BRCAN20280210,
BRCAN20283190, BRCOC20001860, BRCOC20006370, BRCOC20027510,
BRCOC20055420, BRCOC20099370, BRCOC20178270, BRCOC20178560,
BRHIP20003120, BRHIP20005340, BRHIP20174040, BRHIP20176420,
BRHIP20191490, BRHIP20191860, BRHIP20194940, BRHIP20195890,
BRHIP20222280, BRHIP20249110, BRHIP20285930, BRHIP30004880,
BRSSN20013420, BRSSN20038200, BRSSN20039370, BRSSN20046790,
BRSSN20066110, BRSSN20101100, BRSSN20120810, BRSSN20187310,
BRTHA20046290, CD34C30004240, COLON10001350, CTONG20004690,
CTONG20052650, CTONG20099550, CTONG20124220, CTONG20125640,
CTONG20128430, CTONG20131560, CTONG20133390, CTONG20153300,
CTONG20153580, CTONG20158040, CTONG20159530, D6OST20003580,
D9OST20023970, DFNES20001530, DFNES20037420, FCBBF10001210,
FCBBF10001710, FCBBF10003770, FCBBF20059090, FCBBF20064520,
FCBBF20068820, FCBBF30010810, FCBBF30024750, FCBBF30025560,
FCBBF30039020, FCBBF30049550, FCBBF30057290, FCBBF30083620,
FCBBF30129630, FCBBF30190850, FCBBF30238870, FCBBF30240960,
FCBBF30243640, FCBBF30279030, FCBBF30281880, FCBBF40001730,
FEBRA10001880, FEBRA20004620, FEBRA20010120, FEBRA20018690,
FEBRA20082010, FEBRA20097310, FEBRA20130190, FEBRA20132740,
FEBRA20144170, FEBRA20195820, FEBRA20223220, FEBRA20233770,
FEBRA20235500, FEHRT20003250, HCHON10001760, HCHON20007380,
HCHON20008320, HCHON20009560, HCHON20015230, HCHON20015980,
HCHON20016040, HCHON20035130, HCHON20036420, HCHON20064590,
HCHON20067700, HCHON20086720, HCHON20100740, HEART20003060,
HEART20017730, HEART20025980, HEART20049410, HHDPC20014320,
HHDPC20030490, HHDPC20084140, HHDPC20091140, HHDPC20091780,
HHDPC20092080, HLUNG20033780, IMR3220002430, KIDNE20007770,
KIDNE20020150, KIDNE20021680, KIDNE20022620, KIDNE20024830,
KIDNE20027950, KIDNE20101370, KIDNE20101510, KIDNE20182690,
LIVER20002160, LIVER20055200, LIVER20055440, LIVER20059810,
LIVER20064690, MESAN20101140, MESAN20125860, MESAN20130220,
MESAN20154010, MESAN20174170, NOVAR10000910, NT2NE20010490,
NT2NE20118960, NT2NE20157470, NT2RI20040990, NT2RI20041880,
NT2RI20048840, NT2RI20050960, NT2RI20240080, NT2RP60000770,
NT2RP70027380, NT2RP70032610, NT2RP70037240, NT2RP70192730,
NT2RP70198350, NTONG20013620, NTONG20015870, NTONG20028070,
NTONG20067830, NTONG20070200, NTONG20090600, NTONG20092330,
OCBBF20006770, OCBBF20037440, OCBBF20046120, OCBBF20049300,
OCBBF20053490, OCBBF20053730, OCBBF20054760, OCBBF20071840,
OCBBF20072240, OCBBF20078920, OCBBF20108430, OCBBF20108580,
OCBBF20127140, OCBBF20129360, OCBBF20145760, OCBBF20153350,
OCBBF20173980, OCBBF20178880, PEBLM10000710, PEBLM20013120,
PERIC10000250, PLACE60060420, PLACE60177140, PROST20100460,
PROST20159240, PROST20169800, PROST20176170, PUAEN20018820,
PUAEN20030180, PUAEN20055020, PUAEN20083140, SKMUS20018230,
SKMUS20018500, SKMUS20021530, SKMUS20024750, SKMUS20029200,
SKMUS20048970, SKMUS20049030, SKNSH20008190, SKNSH20089400,
SMINT20001760, SMINT20026890, SMINT20028820, SMINT20050750,
SMINT20073650, SMINT20105330, SMINT20112730, SMINT20121220,
SMINT20127350, SMINT20127930, SMINT20136130, SMINT20138900,
SMINT20153260, SMINT20155180, SMINT20179740, SMINT20190170,
SMINT20191420, SPLEN20006070, SPLEN20011410, SPLEN20026950,
SPLEN20027440, SPLEN20039240, SPLEN20079260, SPLEN20095410,
SPLEN20146450, SPLEN20147390, SPLEN20151210, SPLEN20160450,
SPLEN20170310, SPLEN20179180, SPLEN20186430, SPLEN20212730,
SPLEN20243830, SPLEN20245300, SPLEN20250390, SPLEN20252190,
SPLEN20267650, SPLEN20305620, STOMA20001830, STOMA20005390,
STOMA20008880, STOMA20010250, STOMA20034770, STOMA20046680,
STOMA20056670, STOMA20064470, STOMA20077450, STOMA20080500,
STOMA20083610, STOMA20088380, SYNOV20001520, SYNOV20001730,
SYNOV2.0002790, SYNOV20002970, SYNOV20007000, SYNOV20008240,
SYNOV20009230, SYNOV20010880, SYNOV20011110, TBAES20003770,
TESOP20004000, TESOP20005270, TESTI20031270, TESTI20036380,
TESTI20044310, TESTI20067200, TESTI20116830, TESTI20121550,
TESTI20156100, TESTI20168480, TESTI20208400, TESTI20215990,
TESTI20231940, TESTI20234360, TESTI20237520, TESTI20238610,
TESTI20239510, TESTI20249990, TESTI20266740, TESTI20316870,
TESTI20318090, TESTI20335050, TESTI20335200, TESTI20343570,
TESTI20352620, TESTI20368330, TESTI20369650, TESTI20385960,
TESTI20392250, TESTI20400940, TESTI20404240, TESTI20420620,
TESTI20436560, TESTI20438570, TESTI20441940, TESTI20442760,
TESTI20443090, TESTI20449200, TESTI20455090, TESTI20455620,
TESTI20456110, TESTI20463580, TESTI20465350, TESTI20465690,
TESTI20467210, THYMU20122730, THYMU20126900, THYMU20130890,
THYMU20159430, THYMU20169680, THYMU20172150, THYMU20180280,
THYMU20193640, THYMU20209590, THYMU20232090, THYMU20247480,
TKIDN10000010, TKIDN20004640, TKIDN20047480, TRACH20016210,
TRACH20019960, TRACH20050040, TRACH20057690, TRACH20067620,
TRACH20077540, TRACH20079690, TRACH20096610, TRACH20105870,
TRACH20121380, TRACH20154860, TRACH20162860, TRACH20163170,
TRACH20164980, TRACH20190240, TSTOM20005690, TUTER20002830,
UTERU20030570, UTERU20116570, UTERU20144640, UTERU20151980,
UTERU20158800, UTERU20183640, UTERU20185230
[0460] In particular, hit data of the following 386 clones for
Swiss-Prot, or GenBank, UniGene, or nr corresponded to genes or
proteins which had been deposited in the Online Mendelian
Inheritance in Man (OMIM), which is the human gene and disease
database, (the OMIM Number is shown in the parenthesis after the
Clone Name).
[0461] ADIPS20004250 (601505), ADRGL10001470 (202010;103900),
ADRGL20011190 (182790), ADRGL20018300 (600025), ADRGL20035850
(202110), ADRGL20078100 (103270), ASTRO10001650 (126660),
ASTRO20008010 (603899), ASTRO20027430 (179555), ASTRO20106150
(602537), ASTRO20108190 (191092), ASTRO20168470 (604077),
BLADE20003400 (601276), BLADE20003890 (604077), BRACE20038480
(601504), BRACE20039540 (600169), BRACE20059370 (130500;266140),
BRACE20108130 (605413), BRACE20108880 (603758), BRACE20115920
(300023),
[0462] BRACE20116460 (603150), BRACE20232840 (601213),
BRACE20248260 (600813), BRACE20253330 (604990), BRACE20284100
(602415), BRALZ20013500 (602470), BRALZ20017430 (600658),
BRALZ20018340 (600547), BRAMY20000520 (164020), BRAMY20025840
(602327), BRAMY20120910 (600188), BRAMY20134140 (603931),
BRAMY20135900 (601342), BRAMY20162510 (300098), BRAMY20174550
(605464), BRAMY20210400 (603809), BRAMY20211390 (602212),
BRAMY20242470 (605000), BRAMY20245300 (605367), BRAMY20266850
(605609), BRAMY20285160 (120700), BRAWH20016620 (605762),
BRAWH20028110 (602330), BRAWH20064050 (135820), BRAWH20096780
(602277), BRAWH20110960 (603481), BRAWH20113430 (602649),
BRAWH20114000 (138130), BRAWH20118230 (112267), BRAWH20121640
(604437), BRAWH20128270 (601997), BRAWH20137480 (602330),
BRCAN20103740 (602566), BRCAN20224720 (600923;176200),
BRCAN20279700 (604205), BRCAN20280210 (194538), BRCAN20283190
(602118), BRCOC20001860 (604346), BRCOC20006370 (603784),
BRCOC20027510 (179555), BRCOC20055420 (603801), BRCOC20099370
(606045), BRCOC20178270 (194558), BRCOC20178560 (602567),
BRHIP20003120 (604249), BRHIP20005340 (147586), BRHIP20174040
(602658), BRHIP20176420 (164020), BRHIP20191490 (600009),
BRHIP20191860 (602272), BRHIP20194940 (604696), BRHIP20195890
(602211), BRHIP20222280 (603899), BRHIP20249110 (142600),
BRHIP20285930 (602626), BRHIP30004880 (188840), BRSSN20013420
(300272), BRSSN20038200 (602306), BRSSN20039370 (194531),
BRSSN20046790 (604077), BRSSN20066110 (605248), BRSSN20101100
(600188), BRSSN20120810 (142440), BRSSN20187310 (182900),
BRTHA20046290 (602644), COLON10001350 (146900), CTONG20004690
(600019), CTONG20052650 (603871), CTONG20099550 (190370),
CTONG20124220 (184756), CTONG20125640 (180510), CTONG20128430
(601797), CTONG20131560 (103390), CTONG20133390 (604077),
CTONG20153300 (604334), CTONG20153580 (605652), CTONG20158040
(602862), CTONG20159530 (600395), D6OST20003580 (602443),
D9OST20023970 (601525), DFNES20001530 (164500), DFNES20037420
(139259), FCBBF10001210 (602461), FCBBF10001710 (194558),
FCBBF10003770 (604597), FCBBF20059090 (194542), FCBBF20064520
(164020), FCBBF20068820 (194558), FCBBF30010810 (603899),
FCBBF30024750 (603706), FCBBF30025560 (600494), FCBBF30039020
(602835), FCBBF30049550 (106410), FCBBF30057290 (194556),
FCBBF30083620 (300022), FCBBF30129630 (603899), FCBBF30190850
(131210), FCBBF30238870 (602320), FCBBF30240960 (604078),
FCBBF30243640 (601961), FCBBF30279030 (605208), FCBBF30281880
(602517), FCBBF40001730 (176981), FEBRA10001880 (605451),
FEBRA20004620 (600278), FEBRA20010120 (600368), FEBRA20018690
(194542), FEBRA20082010 (602187), FEBRA20097310 (602895),
FEBRA20130190 (605863), FEBRA20132740 (602654), FEBRA20144170
(601685), FEBRA20195820 (604074), FEBRA20223220 (604633),
FEBRA20233770 (603347), FEBRA20235500 (312090), FEHRT20003250
(600286), HCHON10001760 (605315), HCHON20007380 (600833),
HCHON20008320 (604077), HCHON20009560 (194548), HCHON20015230
(604646), HCHON20015980 (604789), HCHON20016040 (146732),
HCHON20035130 (194529), HCHON20036420 (603434), HCHON20064590
(103950), HCHON20067700 (603054), HCHON20086720 (146732),
HCHON20100740 (602281), HEART20003060 (109480), HEART20017730
(106410), HEART20025980 (602127), HEART20049410 (603777),
HHDPC20014320 (602714), HHDPC20030490 (603795), HHDPC20084140
(605184), HHDPC20091140 (603054), HHDPC20091780 (227400),
HHDPC20092080 (146732), HLUNG20033780 (600888), IMR3220002430
(602923), KIDNE20007770 (114890), KIDNE20020150 (140550;603012),
KIDNE20021680 (601609), KIDNE20022620 (603590), KIDNE20024830
(604205), KIDNE20027950 (194531), KIDNE20101370 (602580),
KIDNE20101510 (191845), KIDNE20182690 (605226), LIVER20002160
(600816), LIVER20055200 (604814), LIVER20055440 (605277),
LIVER20059810 (230350), LIVER20064690 (601841), MESAN20101140
(602567), MESAN20125860 (155750), MESAN20130220 (603778),
MESAN20154010 (180480), MESAN20174170 (602516), NOVAR10000910
(159350), NT2NE20010490 (603899), NT2NE20118960 (180490),
NT2NE20157470 (217000), NT2RI20040990 (106410), NT2RI20041880
(160775), NT2RI20048840 (139360), NT2RI20050960 (606103),
NT2RI20240080 (603419), NT2RP60000770 (603044), NT2RP70027380
(118423), NT2RP70032610 (172430), NT2RP70037240 (604108),
NT2RP70192730 (278000), NT2RP70198350 (300043), NTONG20013620
(604125), NTONG20015870 (123940), NTONG20028070 (602369),
NTONG20067830 (182900), NTONG20070200 (194558), NTONG20090600
(313440), NTONG20092330 (153700), OCBBF20006770 (154500),
OCBBF20037440 (602290), OCBBF20046120 (601262), OCBBF20049300
(602277), OCBBF20053490 (154550;602579), OCBBF20053730 (603604),
OCBBF20054760 (603453), OCBBF20071840 (604077), OCBBF20072240
(604331), OCBBF20078920 (602120), OCBBF20108430 (139360),
OCBBF20108580 (300103), OCBBF20127140 (139380), OCBBF20129360
(602142), OCBBF20145760 (600395), OCBBF20153350 (601935),
OCBBF20173980 (603524), OCBBF20178880 (601617), PEBLM10000710
(601007), PEBLM20013120 (602288), PERIC10000250 (603582),
PLACE60060420 (180469), PLACE60177140 (600022), PROST20100460
(158374), PROST20159240 (606019), PROST20169800 (604426),
PROST20176170 (605903), PUAEN20018820 (164740), PUAEN20030180
(603263), PUAEN20055020 (604677), PUAEN20083140 (604762),
SKMUS20018230 (603768), SKMUS20018500 (601402), SKMUS20021530
(606045), SKMUS20024750 (179555), SKMUS20029200 (605758),
SKMUS20048970 (102610), SKMUS20049030 (161650), SKNSH20008190
(604075), SKNSH20089400 (603070), SMINT20001760 (194558),
SMINT20026890 (602127), SMINT20028820 (604719), SMINT20050750
(182120), SMINT20073650 (146900), SMINT20105330
(230500;230600;230650;253010), SMINT20112730 (146900),
SMINT20121220 (160776), SMINT20127350 (180740), SMINT20127930
(146900), SMINT20136130 (147220), SMINT20138900 (125660;601419),
SMINT20153260 (602201), SMINT20155180 (603004), SMINT20179740
(147020), SMINT20190170 (146900), SMINT20191420 (102770),
[0463] SPLEN20006070 (182900), SPLEN20011410 (602732),
SPLEN20026950 (600014), SPLEN20027440 (106410), SPLEN20039240
(140550;603012), SPLEN20079260 (604074), SPLEN20095410 (602277),
SPLEN20146450 (602861), SPLEN20147390 (604078), SPLEN20151210
(600267), SPLEN20160450 (604375), SPLEN20170310 (605216),
SPLEN20179180 (605890), SPLEN20186430 (600052), SPLEN20212730
(114230), SPLEN20243830 (601796), SPLEN20245300 (606004),
SPLEN20250390 (114220), SPLEN20252190 (604077), SPLEN20267650
(602277), SPLEN20305620 (126064), STOMA20001830 (146900),
STOMA20005390 (146900), STOMA20008880 (601652;137750),
STOMA20010250 (605786), STOMA20034770 (146900), STOMA20046680
(164772), STOMA20056670 (146900), STOMA20064470 (173320),
STOMA20077450 (314370), STOMA20080500 (605414), STOMA20083610
(146900), STOMA20088380 (146900), SYNOV20001520 (147200),
SYNOV20001730 (147120), SYNOV20002790 (147120), SYNOV20002970
(147120), SYNOV20007000 (147120), SYNOV20008240 (147120),
SYNOV20009230 (146900), SYNOV20010880 (147120), SYNOV20011110
(147120), TBAES20003770 (118990), TESOP20004000 (116810),
TESOP20005270 (600641), TESTI20031270 (191161), TESTI20036380
(126650;214700), TESTI20044310 (179555), TESTI20067200 (176312),
TESTI20116830 (603142), TESTI20121550 (600862), TESTI20156100
(602253), TESTI20168480 (188840), TESTI20208400 (164031),
TESTI20215990 (605652), TESTI20231940 (604200), TESTI20234360
(601052), TESTI20237520 (604212), TESTI20238610 (300097),
TESTI20239510 (604334),
[0464] TESTI20249990 (164500), TESTI20266740 (605198),
TESTI20316870 (605497), TESTI20318090 (604077), TESTI20335050
(605209), TESTI20335200 (109770), TESTI20343570 (190470),
TESTI20352620 (176801;249900), TESTI20368330 (157680),
TESTI20369650 (602052), TESTI20385960 (605970), TESTI20392250
(605541), TESTI20400940 (117143), TESTI20404240 (602725),
TESTI20420620 (602955), TESTI20436560 (150330), TESTI20438570
(603577), TESTI20441940 (604119), TESTI20442760 (603491),
TESTI20443090 (602954), TESTI20449200 (604101),
[0465] TESTI20455090 (148070), TESTI20455620 (140560),
TESTI20456110 (109092), TESTI20463580 (603486), TESTI20465350
(123830), TESTI20465690 (605468), TESTI20467210 (600833),
THYMU20122730 (604700), THYMU20126900 (603370), THYMU20130890
(603675), THYMU20159430 (146900), THYMU20169680 (601441),
THYMU20172150 (605000), THYMU20180280 (600549), THYMU20193640
(603083;164021), THYMU20209590 (602378), THYMU20232090 (601717),
THYMU20247480 (604077), TKIDN10000010 (605034), TKIDN20004640
(137028), TKIDN20047480 (602399), TRACH20016210 (136836),
TRACH20019960 (182310), TRACH20050040 (603784), TRACH20057690
(164731), TRACH20067620 (600429;110800), TRACH20077540 (300080),
TRACH20079690 (604078), TRACH20096610 (150330), TRACH20105870
(600495), TRACH20121380 (602513), TRACH20154860 (180240),
TRACH20162860 (603845), TRACH20163170 (601739), TRACH20164980
(602277), TRACH20190240 (604633), TSTOM20005690 (605775),
TUTER20002830 (602719), UTERU20030570 (602023;241200),
UTERU20116570 (602330),
UTERU20144640 (228000), UTERU20151980 (602038), UTERU20158800
(600738), UTERU20183640 (601281), UTERU20185230 (605333)
[0466] The clones predicted to belong to the category of enzyme
and/or metabolism-related protein are the following 206 clones.
[0467] 3NB6910001910, ADRGL10001470, ADRGL20035850, ADRGL20078100,
ASTRO20105820, ASTRO20106150, ASTRO20130500, ASTRO20145760,
BRACE20027620, BRACE20038000, BRACE20062640, BRACE20096200,
BRACE20107530, BRACE20108130, BRACE20108880, BRACE20116460,
BRACE20148240, BRACE20185680, BRACE20253160, BRALZ20017430,
BRALZ20018340, BRAMY20104640, BRAMY20134140, BRAMY20153110,
BRAMY20213100, BRAMY20252720, BRAWH20016620, BRAWH20105840,
BRAWH20112940, BRAWH20114000, BRAWH20117950, BRAWH20125380,
BRAWH20132190, BRAWH20171030, BRCAN20054490, BRCAN20224720,
BRCAN20280360, BRCAN20283190, BRCAN20283380, BRCOC20001860,
BRCOC20031250, BRCOC20055420, BRCOC20091960, BRCOC20144000,
BRHIP10001290, BRHIP20005530, BRHIP20096850, BRHIP20103090,
BRHIP20174040, BRHIP20249110, BRSSN20013420, BRSSN20015790,
BRSSN20120810, BRSSN20146100, CTONG20095340, CTONG20106520,
CTONG20118250, CTONG20127450, CTONG20140580, CTONG20153300,
CTONG20158040, D3OST20006180, D6OST20003580, DFNES20031920,
DFNES20071130, FCBBF10001820, FCBBF10003670, FCBBF30012350,
FCBBF30012810, FCBBF30175310, FCBBF30243640, FEBRA10001880,
FEBRA20007620, FEBRA20130190, FEBRA20144170, FEBRA20167390,
FEBRA20196630, FEHRT20003250, HCHON10001760, HCHON20003220,
HCHON20015350, HEART20034320, HEART20090000, HHDPC20014320,
KIDNE20002520, KIDNE20008010, KIDNE20021680, KIDNE20022620,
KIDNE20028390, KIDNE20028720, KIDNE20107620, LIVER20059810,
MESAN20154010, NT2NE20118960, NT2NE20157470, NT2RI20005750,
NT2RI20244600, NT2RI20273230, NT2RP70032610, NT2RP70045590,
NT2RP70192730, NT2RP70195430, NTONG20009770, NTONG20013620,
NTONG20046140, OCBBF20028650, OCBBF20030910, OCBBF20046690,
OCBBF20050770, OCBBF20053430, OCBBF20053490, OCBBF20053730,
OCBBF20054760, OCBBF20078920, OCBBF20124360, OCBBF20129360,
OCBBF20178880, PEBLM20044520, PEBLM20052820, PEBLM20060490,
PERIC10000250, PLACE50000660, PROST20083600, PROST20169800,
PUAEN20015260, PUAEN20030180, SKMUS20018230, SMINT20028820,
SMINT20049090, SMINT20102780, SMINT20105330, SMINT20106290,
SMINT20110660, SMINT20152940, SMINT20191420, SMINT20191530,
SPLEN20021660, SPLEN20026950, SPLEN20121750, SPLEN20145720,
SPLEN20149240, SPLEN20150940, SPLEN20151210, SPLEN20173510,
SPLEN20212730, SPLEN20250390, SPLEN20305620, STOMA20006860,
STOMA20077450, TBAES20002550, TBAES20003150, TESOP20004000,
TESOP20005270, TESTI20001000, TESTI20002720, TESTI20002780,
TESTI20060400, TESTI20066670, TESTI20082330, TESTI20083200,
TESTI20108720, TESTI20116830, TESTI20143390, TESTI20148000,
TESTI20216370, TESTI20232140, TESTI20234360, TESTI20237520,
TESTI20239510, TESTI20266740, TESTI20314180, TESTI20334410,
TESTI20343570, TESTI20352620, TESTI20355020, TESTI20366910,
TESTI20368330, TESTI20369650, TESTI20375340, TESTI20397760,
TESTI20416640, TESTI20432750, TESTI20463580, TESTI20465350,
TESTI20471410, TESTI20473830, THYMU20023380, THYMU20111830,
THYMU20126900, THYMU20169680, THYMU20202890, TKIDN20004640,
TKIDN20047480, TRACH20003590, TRACH20016210, TRACH20019960,
TRACH20041830, TRACH20057690, TRACH20067620, TRACH20084720,
TRACH20085830, TRACH20162860, UTERU20064860, UTERU20144640,
UTERU20146310, UTERU20151980
[0468] The clones predicted to belong to the category of
cytoskeleton-related protein are the following 75 clones.
[0469] ADRGL20011190, ADRGL20018300, ASTRO10001650, ASTRO20055750,
BRACE20003070, BRACE20059370, BRACE20163350, BRAMY20121620,
BRAMY20157820, BRAMY20242470, BRAWH20028110, BRAWH20137480,
BRCAN20003460, BRCOC20008160, BRCOC20059510, BRHIP20115080,
BRHIP20137230, BRHIP20167880, BRHIP20283030, BRHIP20285830,
BRSSN20187310, CTONG10002770, CTONG20052900, CTONG20121580,
FCBBF10001150, FCBBF30013770, FCBBF30015940, FCBBF30049550,
FEBRA20024100, FEBRA20237640, HCHON20015980, HCHON20068410,
HEART20017730, HEART20025980, HEART20061950, HEART20077670,
HLUNG20016330, KIDNE20118580, MESAN20004570, NT2RI20040990,
NT2RI20041880, NT2RP70037240, NT2RP70062230, NTONG20015870,
NTONG20056570, NTONG20067830, NTONG20090600, OCBBF20107090,
OCBBF20155060, PLACE60079250, PUAEN20040670, SKMUS20001980,
SKMUS20016220, SKMUS20048970, SKMUS20049030, SMINT20024570,
SMINT20026890, SMINT20121220, SMINT20138900, SPLEN20006070,
SPLEN20027440, SPLEN20142100, TESTI20063830, TESTI20094230,
TESTI20278400, TESTI20371030, TESTI20417300, TESTI20436560,
TESTI20455090, THYMU20105190, THYMU20172150, THYMU20209590,
TRACH20096610, UMVEN10001560, UTERU20116570
[0470] The clones predicted to belong to the category of nuclear
protein and/or RNA synthesis-related protein are the following 65
clones.
[0471] BRACE20057190, BRACE20064880, BRACE20248260, BRACE20253160,
BRAMY20000520, BRAMY20120910, BRAWH20113430, BRAWH20171030,
BRCAN10001490, BRCAN20283190, BRCOC20037320, BRCOC20178560,
BRHIP20106100, BRHIP20176420, BRHIP20243470, BRSSN20101100,
CTONG20114290, CTONG20125540, CTONG20131560, CTONG20140580,
DFNES20001530, FCBBF20064520, FEBRA20007620, FEBRA20010120,
FEBRA20097310, FEBRA20144170, FEBRA20174410, FEBRA20215500,
IMR3220002430, MESAN20101140, NT2RI20273230, OCBBF20028650,
OCBBF20030910, OCBBF20078920, PROST20104000, PUAEN20018820,
SKMUS20007010, SMINT20127350, SMINT20177360, SMINT20191530,
SPLEN20008740, SPLEN20146450, STOMA20046680, TESTI20082330,
TESTI20094470, TESTI20121550, TESTI20208400, TESTI20234360,
TESTI20237520, TESTI20249990, TESTI20334410, TESTI20355020,
TESTI20368330, TESTI20392760, TESTI20408970, TESTI20436560,
TESTI20438570, TESTI20443090, THYMU20193640, THYMU20202890,
THYMU20241210, TRACH20096610, TUTER20002830, UTERU20151980,
UTERU20176320
[0472] The clones predicted to belong to the category of protein
synthesis and/or transport-related protein are the following 62
clones.
[0473] 3NB6910001910, ASTRO20106150, ASTRO20130500, ASTRO20141350,
BRACE20038480, BRACE20052160, BRACE20057620, BRACE20106840,
BRACE20172980, BRACE20192440, BRAWH20110960, BRCOC20037320,
BRHIP20005530, BRSSN20120810, BRSTN20005360, CTONG20009770,
CTONG20114290, CTONG20125640, CTONG20153300, D6OST20003580,
DFNES20037420, FCBBF30012810, FEBRA20080810, HCHON20064590,
HHDPC20014320, HHDPC20084140, HLUNG20017120, LIVER20064690,
NT2NE20132170, NT2NE20157470, NT2RP70133740, NTONG20009770,
NTONG20075220, NTONG20076930, OCBBF20030910, OCBBF20035930,
OCBBF20153340, PLACE60060420, SMINT20152940, SPLEN20008740,
SPLEN20103950, SPLEN20118300, SPLEN20212730, SPLEN20250390,
STOMA20077450, TBAES20002550, TESOP20004000, TESTI20239510,
TESTI20278400, TESTI20314180, TESTI20463580, THYMU20111830,
THYMU20122730, THYMU20130890, THYMU20232090, TKIDN10000010,
TRACH20084720, TRACH20105870, TRACH20139820, TRACH20149970,
UTERU20120310, UTERU20188110
[0474] The clones predicted to belong to the category of cellular
defense-related protein are the following 15 clones.
BRCOC20144000, CTONG20092680, KIDNE20020150, LIVER20002160,
NT2RI20050960, NT2RP70045590, OCBBF20128120, PLACE60003480,
SKNSH20089400, SMINT20106290, SPLEN20039240, TESTI20001000,
TESTI20455620, TRACH20028030, UTERU20176320
[0475] The clones predicted to belong to the category of
development and/or differentiation-related protein are the
following 13 clones.
3NB6920014590, BRAMY20211390, CTONG20091080, CTONG20121010,
FCBBF30024750, KIDNE20027250, NT2NE20142210, OCBBF20054200,
PROST10003220, SKMUS20007010, SPLEN20179810, STOMA20063250,
TESTI20291960
[0476] The clones predicted to belong to the category of
DNA-binding and/or RNA-binding protein are the following 174
clones.
[0477] 3NB6920014590, ADIPS20004250, ASTRO20008010, ASTRO20168470,
BLADE20003400, BLADE20003890, BRACE20057620, BRACE20060890,
BRACE20064880, BRACE20068590, BRACE20248260, BRACE20253160,
BRAMY20000520, BRAMY20213100, BRAMY20260910, BRAMY20270730,
BRAWH20028110, BRAWH20075700, BRAWH20096780, BRAWH20113430,
BRCAN10001490, BRCAN20280210, BRCAN20283190, BRCOC20144000,
BRCOC20178270, BRCOC20178560, BRHIP20005340, BRHIP20106100,
BRHIP20119330, BRHIP20153600, BRHIP20176420, BRHIP20191860,
BRHIP20195890, BRHIP20222280, BRSSN20039370, BRSSN20046790,
BRSSN20176820, CTONG20050280, CTONG20075860, CTONG20085950,
CTONG20091080, CTONG20092700, CTONG20121010, CTONG20124220,
CTONG20125540, CTONG20133390, CTONG20133520, CTONG20140580,
CTONG20156780, D9OST20033970, FCBBF10001710, FCBBF10004370,
FCBBF20059090, FCBBF20064520, FCBBF20068820, FCBBF30007680,
FCBBF30010810, FCBBF30018550, FCBBF30025560, FCBBF30057290,
FCBBF30083820, FCBBF30129630, FCBBF30240960, FCBBF30246230,
FEBRA20010120, FEBRA20018690, FEBRA20026110, FEBRA20034680,
FEBRA20040530, FEBRA20082010, FEBRA20097310, FEBRA20171380,
FEBRA20195820, FEBRA20196630, FEBRA20233770, HCHON20008320,
HCHON20009560, HCHON20035130, HHDPC10000830, HHDPC20031130,
KIDNE20017130, KIDNE20027250, KIDNE20027950, KIDNE20107390,
KIDNE20182690, LIVER20055440, MESAN20101140, NT2NE20010490,
NT2NE20089970, NT2NE20142210, NT2NE20184900, NT2RP60000770,
NT2RP70044280, NT2RP70102350, NT2RP70157890, NTONG20070200,
OCBBF10001850, OCBBF20020830, OCBBF20037440, OCBBF20046120,
OCBBF20049300, OCBBF20066390, OCBBF20071840, OCBBF20078920,
OCBBF20080410, OCBBF20108190, OCBBF20125530, OCBBF20148280,
PEBLM20060360, PEBLM20060490, PEBLM20078320, PERIC10000250,
PROST10003220, PROST20047390, PROST20066880, PROST20185830,
PROST20189770, PROST20191640, PUAEN20018820, SKNSH20008190,
SKNSH20089400, SMINT20001760, SMINT20127350, SMINT20144800,
SMINT20177360, SMINT20191530, SPLEN20054290, SPLEN20079260,
SPLEN20095410, SPLEN20140800, SPLEN20147390, SPLEN20160450,
SPLEN20252190, SPLEN20267650, STOMA20010250, STOMA20032890,
STOMA20046680, STOMA20063250, TESTI20039400, TESTI20067200,
TESTI20088220, TESTI20094470, TESTI20121550, TESTI20130010,
TESTI20156100, TESTI20204450, TESTI20230850, TESTI20237520,
TESTI20266740, TESTI20318090, TESTI20320670, TESTI20334410,
TESTI20355020, TESTI20378190, TESTI20385960, TESTI20432820,
TESTI20443090, TESTI20456110, THYMU20193640, THYMU20241210,
THYMU20247480, TRACH20079690, TRACH20105870, TRACH20139820,
TRACH20154860, TRACH20163170, TRACH20164980, TRACH20184490,
TUTER20002830, UTERU20099720, UTERU20116570, UTERU20145480,
UTERU20176130, UTERU20185230
[0478] The clones predicted to belong to the category of ATP
binding and/or GTP-binding protein are the following 68 clones.
[0479] 3NB6910001910, BRACE20108130, BRACE20148240, BRAMY20134140,
BRAMY20157820, BRAMY20174550, BRAWH20164460, BRCAN20003460,
BRCAN20054490, BRCAN20283190, BRCOC20059510, BRCOC20144000,
BRHIP20103090, BRHIP20115080, BRHIP20167880, BRSTN20005360,
CD34C30004240, CTONG20095340, CTONG20121580, CTONG20200310,
DFNES20037420, FCBBF20067810, FCBBF30012350, FCBBF30015940,
FEBRA20007620, FEBRA20024100, FEBRA20144170, KIDNE20020150,
KIDNE20028720, LIVER20002160, LIVER20087060, NT2RI20005750,
NT2RI20041880, NT2RI20048840, NT2RI20273230, OCBBF20028650,
OCBBF20046690, OCBBF20054760, OCBBF20108430, OCBBF20108630,
SMINT20121220, SMINT20183530, SMINT20191530, SPLEN20026950,
SPLEN20039240, SPLEN20099700, SPLEN20145720, SPLEN20179180,
STOMA20006860, TESTI20035960, TESTI20355020, TESTI20397760,
TESTI20400940, TESTI20417300, TESTI20443090, TESTI20455620,
THYMU20105190, THYMU20202890, THYMU20209590, TKIDN20004640,
TKIDN20047480, TRACH20005400, TRACH20019960, TRACH20057690,
TRACH20084720, UTERU20168220, UTERU20176320, UTERU20185230
[0480] Among the clones other than the ones shown above,
BRAMY20248490, FCBBF10002800, NTONG20092290, OCBBF20127040,
SMINT20163960, THYMU20279750, TRACH20167220, are clones which were
predicted to highly possibly belong to the category of secretory
protein and/or membrane protein based on the result of domain
search by Pfam.
FCBBF10002800, NTONG20092290, OCBBF20127040, SMINT20163960,
TESTI20478850, THYMU20279750
[0481] The 6 clones shown above are clones which were predicted to
highly possibly belong to the category of glycoprotein-related
protein based on the result of domain search by Pfam.
[0482] BRACE20060720, BRACE20223330, BRALZ20058880, BRAMY20148130,
BRAWH20101360, BRCAN20124080, BRHIP20253660, CTONG10000620,
CTONG20014280, CTONG20124010, KIDNE20109890, MESAN20171520,
OCBBF20109310, OCBBF20140640, PROST20079500, PUAEN20078980,
SPLEN20077500, SPLEN20143180, TESTI20017950, TESTI20184620,
TESTI20208710, TESTI20211160, TESTI20226230, TESTI20234140,
TESTI20258460, TESTI20275030
[0483] The 26 clones shown above are clones which were predicted to
highly possibly belong to the category of signal
transduction-related protein based on the result of domain search
by Pfam.
[0484] ADRGL20048330, ASTRO20064750, ASTRO20084250, BRACE20151320,
BRALZ20058880, BRHIP20207990, CTONG20093950, FCBBF30195640,
FEBRA10001900, FEBRA20090290, FEBRA20214970, FEBRA20222040,
KIDNE20109890, LIVER20087510, MESAN20029400, MESAN20031900,
MESAN20035290, MESAN20136110, NT2NE20130190, PEBLM20060310,
PERIC20004780, PROST20171280, PUAEN20078980, SMINT20115880,
SPLEN20095550, TESTI20023510, TESTI20083940, TESTI20152460,
TESTI20185650, TESTI20189410, TESTI20200710, TESTI20308600,
TESTI20343070, TESTI20369690, TESTI20381040, UTERU20050690
[0485] The 36 clones shown above are clones which were predicted to
highly possibly belong to the category of transcription-related
protein based on the result of domain search by Pfam.
[0486] BGGI120006160, BRACE20053480, BRACE20190040, BRACE20223330,
BRAWH20101360, BRAWH20185060, BRCOC20023230, BRHIP20252450,
BRSSN20105870, BRSSN20117990, BRTHA20000570, CTONG20098440,
CTONG20129960, CTONG20146300, CTONG20155180, FEBRA20025270,
HEART20083640, KIDNE20009470, LIVER20035680, MESAN20029400,
MESAN20031900, MESAN20186700, NOVAR10000150, NTONG20029480,
OCBBF20079310, OCBBF20082830, PEBLM20042900, PLACE60136500,
PLACE60136720, PROST20114390, SKNSH20020540, SMINT20013480,
SMINT20174360, SPLEN20077500, SPLEN20119810, SPLEN20126190,
SPLEN20174260, SPLEN20211220, TESTI20046750, TESTI20057750,
TESTI20061110, TESTI20197940, TESTI20211160, TESTI20226230,
TESTI20255820, TESTI20317600, TESTI20377230, THYMU20111180,
THYMU20115850, THYMU20143270, THYMU20240710, UTERU20055330,
UTERU20055930, UTERU20064000, UTERU20119060
[0487] The 55 clones shown above are clones which were predicted to
highly possibly belong to the category of enzyme and/or
metabolism-related protein based on the result of domain search by
Pfam.
TESTI20127760, TESTI20392270
[0488] The 2 clones shown above are clones which were predicted to
highly possibly belong to the category of cell division and/or cell
proliferation-related protein based on the result of domain search
by Pfam.
FCBBF30262510, MESAN20031900, NT2NE20125050, SMINT20068010,
SPLEN20163560, STOMA20092890, TESTI20382750
[0489] The 7 clones shown above are clones which were predicted to
highly possibly belong to the category of cytoskeleton-related
protein based on the result of domain search by Pfam.
THYMU20118520
[0490] The clone shown above is clone which were predicted to
highly possibly belong to the category of nuclear protein and/or
RNA synthesis-related protein based on the result of domain search
by Pfam.
BRACE20053480, BRACE20240740, KIDNE20009470, OCBBF20140890,
SMINT20035690, UTERU20064000
[0491] The 6 clones shown above are clones which were predicted to
highly possibly belong to the category of protein synthesis and/or
transport-related protein based on the result of domain search by
Pfam.
[0492] ADRGL20048330, ASTRO20064750, ASTRO20084250, BRACE20151320,
BRACE20190040, BRACE20223330, BRALZ20058880, BRAMY20103570,
BRCOC20023230, BRHIP20207990, BRTHA20000570, CTONG20093950,
CTONG20129960, CTONG20146300, CTONG20155180, CTONG20160560,
FCBBF10004120, FCBBF30195640, FEBRA10001900, FEBRA20090290,
FEBRA20214970, FEBRA20222040, HCHON20008150, HEART20083640,
KIDNE20109890, LIVER20035680, LIVER20087510, MESAN20029400,
MESAN20031900, MESAN20035290, MESAN20136110, MESAN20186700,
NT2NE20130190, NT2RI20025640, NTONG20029480, PEBLM20060310,
PERIC20004780, PROST20114390, PROST20171280, PUAEN20078980,
SMINT20115880, SPLEN20095550, SPLEN20119810, TESTI20023510,
TESTI20057750, TESTI20083940, TESTI20152460, TESTI20185650,
TESTI20189410, TESTI20200710, TESTI20308600, TESTI20343070,
TESTI20369690, TESTI20381040, THYMU20115850, UTERU20050690,
UTERU20055330
[0493] The 57 clones shown above are clones which were predicted to
highly possibly belong to the category of DNA-binding and/or
RNA-binding protein based on the result of domain search by
Pfam.
PLACE60136720
[0494] The clone shown above is a clone which was predicted to
highly possibly belong to the category of ATP-binding and/or
GTP-binding protein based on the result of domain search by
Pfam.
[0495] The 213 clones shown below are clones which were
unassignable to any of the above-mentioned categories, but have
been predicted to have some functions based on homology search for
their full-length nucleotide sequences and motif search in their
deduced ORFs. Clone Name, Definition in the result of homology
search or Motif Name in the motif search, demarcated by a double
slash mark (//), are shown below.
ADRGL20028570//Rattus norvegicus MG87 mRNA, complete cds.
ADRGL20061930//transposon-derived Buster1 transposase-like
protein
ASTRO20012490//Eukaryotic initiation factor 1A
ASTRO20072210//PERIAXIN.
ASTRO20114370//Mus musculus SMAR1 mRNA, complete cds.
ASTRO20125520//dnaj protein [Schizosaccharomyces pombe]
ASTRO20143630//KH domain// Bacterial regulatory proteins, crp
family
ASTRO20155290//TPR Domain// TPR Domain// TPR Domain
ASTRO20181690//oocyte-specific protein P100
BGGI110001930//UBX domain
BRACE20011070//Mus musculus F-box protein FBX15 mRNA, partial
cds.
BRACE20039440//Drosophila melanogaster CHARYBDE (charybde) mRNA,
complete cds.
BRACE20050900//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
BRACE20053280//Mus musculus Pdz-containing protein (Pdzx) mRNA,
complete cds.
BRACE20057730//toxin sensitivity protein KTI12 homolog
BRACE20058580//Homo sapiens HCMOGT-1 mRNA for sperm antigen,
complete cds.
BRACE20063780//NOL1/NOP2/sun family
BRACE20269200//Heat-labile enterotoxin alpha chain
BRACE20276430//Homo sapiens retinoblastoma-associated protein
RAP140 mRNA, complete cds.
BRACE20286360//Alpha adaptin carboxyl-terminal domain
BRAMY10001300//Homo sapiens MAGE-E1b mRNA, complete cds.
BRAMY20045240//Flagellar L-ring protein
BRAMY20054880//Rattus norvegicus KPL2 (Kpl2) mRNA, complete
cds.
BRAMY20167060//Collagen triple helix repeat (20 copies)
BRAMY20184670//Homo sapiens mRNA for ALEX1, complete cds.
BRAMY20217460//Homo sapiens cardiac voltage gated potassium channel
modulatory subunit mRNA, complete cds, alternatively spliced.
BRAMY20240040//Homo sapiens suppressor of white apricot homolog 2
(SWAP2) mRNA, complete cds.
BRAMY20247110//Mus musculus semaphorin cytoplasmic
domain-associated protein 3A (Semcap3) mRNA, complete cds.
BRAWH20004600//Mus musculus mRNA for NAKAP95, complete cds.
BRAWH20011710//cytoplasmic linker 2
BRAWH20012390//Trichomonas vaginalis mRNA for centrin (ce1
gene).
BRAWH20017010//Homo sapiens testes development-related NYD-SP22
mRNA, complete cds.
BRAWH20029630//Homo sapiens bet3 (BET3) mRNA, complete cds.
BRAWH20138660//Homo sapiens stonin 2 mRNA, complete cds.
BRCOC20008500//Human ras inhibitor mRNA, 3' end.
BRCOC20026640//Gag P30 core shell protein
BRCOC20035130//14-3-3 PROTEIN EPSILON (MITOCHONDRIAL IMPORT
STIMULATION FACTOR L SUBUNIT) (PROTEIN KINASE C INHIBITOR
PROTEIN-1) (KCIP-1) (14-3-3E).
BRCOC20074760//CDC4-LIKE PROTEIN (FRAGMENT).
BRCOC20110100//Integrase core domain
BRCOC20176520//Rattus norvegicus mRNA for type II brain 4.1,
complete cds.
BRHIP20001630//Protein of unknown function DUF16
BRHIP20132860//Homo sapiens rhophilin-like protein mRNA, complete
cds.
BRHIP20143730//MYND finger
BRHIP20175420//Mus musculus partial mRNA for stretch responsive
protein 278 (sr278 gene).
BRHIP20236950//Outer Capsid protein VP4 (Hemagglutinin)
BRSSN20014260//RIBONUCLEASE INHIBITOR.
BRSSN20018690//Homo sapiens NY-REN-25 antigen mRNA, partial
cds.
BRSSN20021600//RING CANAL PROTEIN (KELCH PROTEIN).
BRSSN20177570//Phosducin
BRSTN10000830//Kelch motif// Kelch motif// Kelch motif// Kelch
motif
CTONG10000220//Mus musculus cerebellar postnatal development
protein-1 (Cpd1) mRNA, partial cds.
CTONG10000930//Armadillo/beta-catenin-like repeats
CTONG20027090//Glypican// Leucine Rich Repeat// Leucine Rich
Repeat
CTONG20076130//ZINC FINGER PROTEIN 185 (LIM-DOMAIN PROTEIN ZNF185)
(P1-A).
CTONG20096750//Disintegrin
CTONG20100240//Mus musculus radial spokehead-L protein (Rshl1)
mRNA, complete cds.
CTONG20139860//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete cds.
CTONG20143690//MYND finger
CTONG20149460//RING CANAL PROTEIN (KELCH PROTEIN).
CTONG20165050//Keratin, high sulfur B2 protein
CTONG20186320//RING CANAL PROTEIN (KELCH PROTEIN).
D3OST20013280//ARP2/3 COMPLEX 16 KDA SUBUNIT (P16-ARC).
D3OST20024360//Homo sapiens neuroendocrine differentiation factor
mRNA, complete cds.
D9OST20031370//Homo sapiens mRNA for partial putative
TCPTP-interacting protein (ptpip5 gene).
DFNES20014040//TRICHOHYALIN.
FCBBF10000630//Homo sapiens huntingtin interacting protein HYPB
mRNA, partial cds.
FCBBF10000770//Homo sapiens REC8 mRNA, partial cds.
FCBBF10005060//CELLULAR RETINALDEHYDE-BINDING PROTEIN (CRALBP).
FCBBF10005500//Keratin, high sulfur B2 protein
FCBBF20014270//ACYL-COA-BINDING PROTEIN (ACBP) (DIAZEPAM BINDING
INHIBITOR) (DBI) (ENDOZEPINE) (EP).
FCBBF20042170//Homo sapiens NIBAN mRNA, complete cds.
FCBBF30016320//SecA protein, amino terminal region
FCBBF30033050//Sm protein
FCBBF30054440//PLAT/LH2 domain
FCBBF30225660//Ank repeat// Ank repeat// Ank repeat// K+ channel
tetramerisation domain// BTB/POZ domain
FCBBF30233680//G10 protein
FCBBF30246630//H. sapiens mRNA for ZYG homologue.
FCBBF30250730//TRICHOHYALIN.
FCBBF30252520//Homo sapiens bicaudal-D (BICD) mRNA, alternatively
spliced, partial cds.
FCBBF30252800//NDRG1 PROTEIN (DIFFERENTIATION-RELATED GENE 1
PROTEIN) (DRG1) (REDUCING AGENTS AND TUNICAMYCIN-RESPONSIVE
PROTEIN) (RTP) (NICKEL-SPECIFIC INDUCTION PROTEIN CAP43).
FCBBF30252850//Mus musculus peripherial benzodiazepine receptor
associated protein (Pap7) mRNA, complete cds.
FCBBF30285280//Keratin, high sulfur B2 protein// Bacterial
regulatory proteins, gntR family
FEBRA20088360//ALPHA-ADAPTIN C (CLATHRIN ASSEMBLY PROTEIN COMPLEX 2
ALPHA-C LARGE CHAIN) (100 KDA COATED VESICLE PROTEIN C) (PLASMA
MEMBRANE ADAPTOR HA2/AP2 ADAPTIN ALPHA C SUBUNIT).
FEBRA20184330//Rattus norvegicus glutamate receptor interacting
protein 2 (GRIP2) mRNA, complete cds.
FEBRA20192420//Cyclin-dependent kinase inhibitor// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif
FEBRA20196370//Cyclin-dependent kinase inhibitor// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif// IQ calmodulin-binding motif// IQ
calmodulin-binding motif
FEBRA20225040//high-glucose-regulated protein 8
HCHON20001560//TRANSCRIPTION FACTOR-LIKE PROTEIN MORF4.
HCHON20003440//Homo sapiens cyclin-D binding Myb-like protein mRNA,
complete cds.
HCHON20010990//TPR Domain
HCHON20059870//Hypothetical protein.
HHDPC20034390//Cereal trypsin/alpha-amylase inhibito
HHDPC20057420//Mus musculus proline-rich protein (Bprp) mRNA,
complete cds.
HHDPC20064600//SUPPRESSOR PROTEIN SRP40.
HLUNG20023340//Mus musculus SLM-1 (Slm1) mRNA, complete cds.
KIDNE20007210//Xenopus laevis mRNA for RPA interacting protein
alpha (ripalpha gene).
KIDNE20028830//K-box region
KIDNE20115080//Homo sapiens mRNA for hNBL4, complete cds.
KIDNE20124400//Homo sapiens mRNA for ALEX1, complete cds.
KIDNE20127100//Drosophila melanogaster Diablo (dbo) mRNA, complete
cds.
KIDNE20127750//Homo sapiens partial mRNA for transport-secretion
protein 2.1 (TTS-2.1 gene).
KIDNE20190740//Rattus norvegicus SNIP-b mRNA, complete cds.
LIVER10004790//EF hand
LIVER20011130//Homo sapiens F-box protein FBL9 mRNA, partial
cds.
LIVER20064100//Ciona intestinalis mRNA for myoplasmin-C1, complete
cds.
LIVER20080530//Drosophila melanogaster forked mRNA for large Forked
protein, complete cds.
MAMGL10000830//Drosophila melanogaster L82B (L82) mRNA, complete
cds.
MESAN20036460//Corticotropin-releasing factor family
MESAN20127350//myelin expression factor-3
MESAN20141920//Human ovarian cancer downregulated myosin heavy
chain homolog (Doc1) mRNA, complete cds.
NT2NE20010400//Homo sapiens GLO13 mRNA, complete cds.
NT2NE20122430//GLYOXYLATE-INDUCED PROTEIN.
NT2NE20158600//erythroid ankyrin--Synechocystis sp. (strain PCC
6803).
NT2RI20001330//Homo sapiens KE03 protein mRNA, partial cds.
NT2RI20009870//lunatic fringe precursor [Mus musculus]
NT2RI20046080//recA bacterial DNA recombination proteins
NT2RI20091730//Molluscan rhodopsin C-terminal tail
NT2RP60000850//Bos taurus RPGR-interacting protein-1 (RPGRIP1)
mRNA, complete cds.
NT2RP70080850//SPRY domain// Adenovirus EB1 55K protein/large
t-an
NT2RP70105210//Myc amino-terminal region
NT2RP70188710//Yeast PIR proteins
NT2RP70194450//Bacterial regulatory proteins, crp family
NTONG20052650//Gallus gallus Xin mRNA, complete cds.
NTONG20064400//REPETIN.
NTONG20064840//Mus musculus slp1 mRNA for synaptotagmin-like
protein 1, complete cds.
NTONG20066460//Mus musculus Gd mRNA for gasdermin, complete
cds.
NTONG20067090//Mus musculus mRNA for Sh3yl1, complete cds.
NTONG20070340//collagen alpha 1(IX) chain
NTONG20083650//TPR Domain// TPR Domain// TPR Domain// PPR repeat//
TPR Domain// PPR repeat// TPR Domain
NTONG20088620//Homo sapiens genethonin 3 mRNA, partial cds.
OCBBF10000540//Mus musculus ris (rjs) mRNA, complete cds.
OCBBF20019380//seizure related gene 6
OCBBF20022900//Homo sapiens SCHIP-1 mRNA, complete cds.
OCBBF20030280//Rattus norvegicus hfb2 mRNA, complete cds.
OCBBF20046470//ARFAPTIN 1.
OCBBF20049840//Homo sapiens mRNA for neurabin II protein.
OCBBF20068490//Mus musculus RW1 protein mRNA, complete cds.
OCBBF20071960//Coturnix coturnix japonica qMEF2D gene.
OCBBF20073540//Homo sapiens p30 DBC mRNA, complete cds.
OCBBF20121390//RING CANAL PROTEIN (KELCH PROTEIN).
OCBBF20127550//Outer Capsid protein VP4 (Hemagglutinin)
OCBBF20148730//RING CANAL PROTEIN (KELCH PROTEIN).
OCBBF20178150//Plasmodium falciparum ADA2-like protein gene,
partial cds.
PEBLM10000240//Domain found in Dishevelled, Eg1-10, and Ple
PROST20047270//CRAL/TR10 domain.
PROST20112970//Sterile alpha motif (SAM)/Pointed domain// SAM
domain (Sterile alpha motif)
PUAEN10000850//Uncharacterized protein family UPF0025//Sec1
family
PUAEN20011880//Mus musculus mRNA for MIWI (piwi), complete cds.
PUAEN20051100//Mus musculus otogelin mRNA, complete cds.
PUAEN20108240//Drosophila melanogaster ankyrin 2 (Ank2) mRNA,
complete cds.
SKMUS20084740//Syndecan domain
SMINT20053300//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.
SMINT20071400//NOL1/NOP2/sun family
SMINT20101440//Human cisplatin resistance associated alpha protein
(hCRA alpha) mRNA, complete cds.
SMINT20110330//pKID domain
SMINT20122910//Mus musculus StAR-related protein 1-4E mRNA, partial
cds.
SMINT20131810//ENV polyprotein (coat polyprotein)
SMINT20168570//Homo sapiens mRNA for stabilin-1 (stab1 gene).
SPLEN20008390//Human placenta (Diff48) mRNA, complete cds.
SPLEN20084600//RING CANAL PROTEIN (KELCH PROTEIN).
SPLEN20128000//Xenopus laevis XMAB21 (Xmab-21) mRNA, complete
cds.
SPLEN20149110//Dishevelled specific domain
SPLEN20171470//Keratin, high sulfur B2 protein
SPLEN20194050//Homo sapiens HOTTL protein mRNA, complete cds.
SPLEN20214580//Mus musculus mdg1-1 mRNA, complete cds.
STOMA20057820//Uncharacterized protein family UPF0024
STOMA20063980//Collagen triple helix repeat (20 copies)
STOMA20069040//Keratin, high sulfur B2 protein
SYNOV20017080//UBX domain
TBAES20000590//Cytochrome P450// Cytochrome P450
TESTI20001170//HORMA domain
TESTI20031810//Bacterial luciferase// Domain of unknown function
DUF28
TESTI20044230//Mus musculus testis-specific Y-encoded-like protein
(Tspyl1) mRNA, complete cds.
TESTI20098350//VAT-Nn domain
TESTI20157520//K+ channel tetramerisation domain// K+ channel
tetramerisation domain
TESTI20170350//Cystine-knot domain
TESTI20192800//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete cds.
TESTI20199750//TRICHOHYALIN.
TESTI20202650//Repeat in HS1/Cortactin
TESTI20229600//Drosophila melanogaster SP2353 mRNA, complete
cds.
TESTI20231920//Gag P30 core shell protein
TESTI20242830//E2 (early) protein, C terminal// Syndecan domain
TESTI20254540//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.
TESTI20320440//THIOREDOXIN.
TESTI20327680//EF hand// EF hand
TESTI20328280//KE2 family protein// Troponin
TESTI20351830//K-box region
TESTI20370020//Bleomycin resistance protein
TESTI20391210//IQ calmodulin-binding motif
TESTI20408150//Keratin, high sulfur B2 protein
TESTI20451990//SAP domain
[0496] TESTI20467970//Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain// Neurohypophysial hormones, N-terminal Domain//
Neurohypophysial hormones, N-terminal Domain// Neurohypophysial
hormones, N-terminal Domain// Neurohypophysial hormones, N-terminal
Domain
THYMU20108310//Mouse NCBP-29 mRNA for PW29, complete cds.
THYMU20142040//WISKOTT-ALDRICH SYNDROME PROTEIN HOMOLOG (WASP).
THYMU20194360//Kelch motif
THYMU20239000//collagen alpha 1(XI) chain
TOVAR20004760//Leucine Rich Repeat// Leucine Rich Repeat// Leucine
Rich Repeat
TRACH20005020//Ank repeat// MutT-like domain
TRACH20007020//TRICHOHYALIN.
TRACH20048450//PROTEIN K4 (PROTEIN K3).
TRACH20068700//Homo sapiens adaptor protein CIKS mRNA, complete
cds.
TRACH20076760//Keratin, high sulfur B2 protein
TRACH20135520//TBC domain// Rhodanese-like domain
TRACH20141240//Mus musculus G21 protein mRNA, complete cds.
TRACH20183170//Rattus norvegicus Sprague-Dawley SM-20 mRNA,
complete cds.
UTERU20000740//Human fusion protein mRNA, complete cds.
UTERU20004240//CGI-96 protein
UTERU20006960//endoplasmic reticulum resident protein 58
UTERU20022940//Human (p23) mRNA, complete cds.
UTERU20046640//Mus musculus ld1Bp (LDLB) mRNA, complete cds.
UTERU20065930//GTP-RHO BINDING PROTEIN 1 (RHOPHILIN).
UTERU20115740//Human PMS2 related (hPMSR3) gene, complete cds.
UTERU20179880//TPR Domain// TPR Domain// TPR Domain// TPR
Domain
[0497] With respect to the remaining 882 clones, there are so far
no information available for estimating their functions. However,
there is the possibility that the functions of these clones will be
revealed in future. Their Clone Names are indicated below.
[0498] 3NB6920014080, ADRGL20000640, ADRGL20012870, ADRGL20013010,
ADRGL20044590, ADRGL20067670, ADRGL20068170, ADRGL20068460,
ADRGL20073570, ADRGL20076360, ADRGL20083310, ASTRO20032120,
ASTRO20100720, ASTRO20111490, ASTRO20114610, ASTRO20136710,
ASTRO20138020, ASTRO20152140, ASTRO20166810, ASTRO20173480,
BLADE20004630, BRACE20019540, BRACE20037660, BRACE20038850,
BRACE20051690, BRACE20054500, BRACE20055180, BRACE20056810,
BRACE20057420, BRACE20058810, BRACE20060840, BRACE20061740,
BRACE20062400, BRACE20062740, BRACE20063800, BRACE20063930,
BRACE20082950, BRACE20090440, BRACE20096540, BRACE20097320,
BRACE20099570, BRACE20106690, BRACE20109370, BRACE20109830,
BRACE20111830, BRACE20114780, BRACE20115450, BRACE20118380,
BRACE20121850, BRACE20136240, BRACE20141080, BRACE20142320,
BRACE20142570, BRACE20148210, BRACE20150310, BRACE20152870,
BRACE20163150, BRACE20165830, BRACE20171240, BRACE20175870,
BRACE20190440, BRACE20220300, BRACE20223280, BRACE20229280,
BRACE20230700, BRACE20235400, BRACE20262930, BRACE20262940,
BRACE20266750, BRACE20267250, BRACE20269710, BRACE20283920,
BRACE20287410, BRALZ20014450, BRALZ20019660, BRALZ20059500,
BRALZ20065600, BRALZ20075450, BRALZ20075760, BRALZ20080310,
BRALZ20088690, BRAMY10001570, BRAMY20004110, BRAMY20011140,
BRAMY20071850, BRAMY20102080, BRAMY20110640, BRAMY20116790,
BRAMY20121190, BRAMY20137560, BRAMY20147540, BRAMY20160700,
BRAMY20163250, BRAMY20163270, BRAMY20167710, BRAMY20168920,
BRAMY20170140, BRAMY20178640, BRAMY20182730, BRAMY20183080,
BRAMY20196000, BRAMY20204450, BRAMY20205740, BRAMY20229840,
BRAMY20230600, BRAMY20250240, BRAMY20250320, BRAMY20261680,
BRAMY20267130, BRAMY20268990, BRAMY20277140, BRAMY20280720,
BRAMY20285930, BRAMY20286820, BRAWH10000930, BRAWH20012410,
BRAWH20014920, BRAWH20016660, BRAWH20100690, BRAWH20103180,
BRAWH20106180, BRAWH20107540, BRAWH20110660, BRAWH20111550,
BRAWH20122770, BRAWH20126190, BRAWH20126980, BRAWH20139410,
BRAWH20142340, BRAWH20147290, BRAWH20155950, BRAWH20158530,
BRAWH20160280, BRAWH20162690, BRAWH20166790, BRAWH20173050,
BRAWH20182060, BRCAN20006200, BRCAN20006390, BRCAN20060190,
BRCAN20126130, BRCAN20143700, BRCAN20147880, BRCAN20216690,
BRCAN2.0237240, BRCAN20263400, BRCAN20273100, BRCAN20273340,
BRCAN20275130, BRCAN20280400, BRCAN20284600, BRCOC20004870,
BRCOC20020850, BRCOC20031000, BRCOC20031870, BRCOC20037400,
BRCOC20093800, BRCOC20105100, BRCOC20117690, BRCOC20119960,
BRCOC20122290, BRCOC20128130, BRCOC20135730, BRCOC20147480,
BRCOC20148330, BRCOC20155970, BRCOC20158240, BRHIP10001740,
BRHIP20104440, BRHIP20105710, BRHIP20107440, BRHIP20110800,
BRHIP20115760, BRHIP20123140, BRHIP20129720, BRHIP20139720,
BRHIP20140630, BRHIP20142850, BRHIP20143860, BRHIP20149540,
BRHIP20153560, BRHIP20169680, BRHIP20169900, BRHIP20170100,
BRHIP20173150, BRHIP20180140, BRHIP20186120, BRHIP20186500,
BRHIP20190070, BRHIP20196410, BRHIP20205090, BRHIP20208420,
BRHIP20214950, BRHIP20227080, BRHIP20230710, BRHIP20232290,
BRHIP20238690, BRHIP20240460, BRHIP20254480, BRHIP20277620,
BRHIP20284800, BRHIP30001110, BRSSN10000920, BRSSN20006340,
BRSSN20015030, BRSSN20028570, BRSSN20038410, BRSSN20046570,
BRSSN20046860, BRSSN20097020, BRSSN20105960, BRSSN20108300,
BRSSN20121030, BRSSN20152380, BRSSN20159070, BRSSN20159820,
BRSTN20000580, BRTHA20046390, CD34C30001250, CD34C30003140,
CD34C30004940, COLON20043180, CTONG20002180, CTONG20028410,
CTONG20038890, CTONG20049410, CTONG20077790, CTONG20082690,
CTONG20091320, CTONG20095270, CTONG20095290, CTONG20096430,
CTONG20097660, CTONG20099630, CTONG20101480, CTONG20105660,
CTONG20106230, CTONG20108210, CTONG20124470, CTONG20126070,
CTONG20128470, CTONG20136300, CTONG20138030, CTONG20139070,
CTONG20140320, CTONG20141650, CTONG20146970, CTONG20147050,
CTONG20150910, CTONG20158150, CTONG20162170, CTONG20163550,
CTONG20164990, CTONG20265130, CTONG20273610, D3OST10002670,
D3OST10002700, D3OST20006540, D3OST20007340, D3OST20024170,
D3OST20024520, D3OST20037970, D3OST30002910, D6OST20004450,
D9OST20000310, D9OST20035800, DFNES10000030, DFNES10001850,
DFNES20010910, DFNES20055270, DFNES20082800, FCBBF10003740,
FCBBF20006780, FCBBF20023700, FCBBF20035280, FCBBF20054280,
FCBBF20056370, FCBBF20071860, FCBBF20072650, FCBBF20075560,
FCBBF20076330, FCBBF30001840, FCBBF30016570, FCBBF30019120,
FCBBF30028180, FCBBF30052180, FCBBF30062880, FCBBF30070770,
FCBBF30071520, FCBBF30170590, FCBBF30178730, FCBBF30189490,
FCBBF30199610, FCBBF30240020, FCBBF30242250, FCBBF30262360,
FCBBF30266780, FCBBF30266920, FCBBF30278630, FCBBF30284720,
FCBBF40001420, FCBBF40005480, FEBRA20003210, FEBRA20017050,
FEBRA20018280, FEBRA20025520, FEBRA20026280, FEBRA20027810,
FEBRA20034360, FEBRA20037500, FEBRA20042190, FEBRA20052910,
FEBRA20060610, FEBRA20072120, FEBRA20079310, FEBRA20082100,
FEBRA20095140, FEBRA20098460, FEBRA20161120, FEBRA20166540,
FEBRA20176800, FEBRA20197110, FEBRA20204000, FEBRA20204060,
FEBRA20216360, FEBRA20226010, FEBRA20229560, FEBRA20232850,
FELNG20002410, HCHON20002260, HCHON20008980, HCHON20009350,
HCHON20011160, HCHON20014970, HCHON20022470, HCHON20036760,
HCHON20043590, HCHON20067220, HCHON20074820, HCHON20076500,
HEART20021840, HEART20037810, HEART20049400, HEART20063340,
HEART20067870, HEART20067890, HEART20074430, HEART20089940,
HEART20095990, HHDPC10000650, HHDPC20006920, HHDPC20057940,
HHDPC20095280, HLUNG20016770, HLUNG20084390, KIDNE20006780,
KIDNE20011170, KIDNE20013730, KIDNE20018730, KIDNE20018970,
KIDNE20021980, KIDNE20029800, KIDNE20067330, KIDNE20079440,
KIDNE20096280, KIDNE20096470, KIDNE20100840, KIDNE20102650,
KIDNE20104300, KIDNE20106740, KIDNE20107500, KIDNE20112000,
KIDNE20120090, KIDNE20122910, KIDNE20132180, KIDNE20138010,
KIDNE20141190, KIDNE20144890, KIDNE20148900, KIDNE20163880,
KIDNE20180710, KIDNE20186780, LIVER10001260, LIVER20011910,
LIVER20028420, LIVER20038540, LIVER20084730, LIVER20085800,
MESAN20106640, MESAN20121130, MESAN20132110, MESAN20138450,
MESAN20157080, MESAN20161590, MESAN20164090, MESAN20182090,
NESOP10001080, NOVAR10001020, NOVAR20003520, NT2NE20003740,
NT2NE20010210, NT2NE20015240, NT2NE20043780, NT2NE20053580,
NT2NE20072200, NT2NE20074250, NT2NE20089610, NT2NE20108540,
NT2NE20110360, NT2NE20146810, NT2NE20152750, NT2NE20172590,
NT2NE20174800, NT2NE20174920, NT2NE20187390, NT2RI20022600,
NT2RI20023160, NT2RI20023590, NT2RI20036670, NT2RI20055790,
NT2RI20069730, NT2RI20198260, NT2RI20203900, NT2RI20207030,
NT2RI20216250, NT2RI20244960, NT2RI20250750, NT2RI20252550,
NT2RP70010740, NT2RP70056750, NT2RP70075240, NT2RP70077660,
NT2RP70085440, NT2RP70110860, NT2RP70111320, NT2RP70130020,
NT2RP70137640, NT2RP70143480, NT2RP70147210, NT2RP70150800,
NT2RP70169110, NT2RP70175670, NT2RP70181970, NT2RP70190640,
NT2RP70203790, NTONG20050620, NTONG20050860, NTONG20065010,
NTONG20077560, NTONG20090680, OCBBF20005230, OCBBF20020150,
OCBBF20029800, OCBBF20032460, OCBBF20041680, OCBBF20045330,
OCBBF20047570, OCBBF20048660, OCBBF20051610, OCBBF20060300,
OCBBF20061720, OCBBF20062140, OCBBF20062410, OCBBF20074140,
OCBBF20076220, OCBBF20079460, OCBBF20081380, OCBBF20084660,
OCBBF20085200, OCBBF20088220, OCBBF20094240, OCBBF20097720,
OCBBF20100400, OCBBF20103130, OCBBF20104040, OCBBF20105570,
OCBBF20107920, OCBBF20111770, OCBBF20118970, OCBBF20126780,
OCBBF20130110, OCBBF20139260, OCBBF20151150, OCBBF20164050,
OCBBF20164670, OCBBF20170690, OCBBF20173060, OCBBF20173250,
OCBBF20178990, OCBBF20186870, OCBBF20189560, PEBLM20024550,
PEBLM20071880, PEBLM20072960, PERIC20002140, PERIC20003860,
PLACE60004630, PLACE60119750, PLACE60138830, PLACE60153220,
PLACE60155130, PLACE60169420, PLACE60181070, PLACE60187690,
PLACE60188340, PROST10004800, PROST20005670, PROST20021010,
PROST20024890, PROST20029270, PROST20052280, PROST20057930,
PROST20059040, PROST20087700, PROST20097950, PROST20111050,
PROST20120050, PROST20121900, PROST20123530, PROST20127400,
PROST20130530, PROST20132600, PROST20133270, PROST20144220,
PROST20149160, PROST20149250, PROST20151240, PROST20152460,
PROST20153320, PROST20166680, PROST20168290, PROST20178360,
PUAEN20025680, PUAEN20027580, PUAEN20044000, PUAEN20045110,
PUAEN20045250, PUAEN20052470, PUAEN20081230, PUAEN20085150,
RECTM10001410, RECTM20003490, RECTM20005100, SKMUS20012010,
SKMUS20031680, SKMUS20046670, SKNMC20006220, SKNSH20034660,
SKNSH20062340, SKNSH20080430, SKNSH20087770, SKNSH20091970,
SMINT20005410, SMINT20008240, SMINT20011140, SMINT20011580,
SMINT20014580, SMINT20015590, SMINT20023280, SMINT20033170,
SMINT20033400, SMINT20042990, SMINT20047810, SMINT20056210,
SMINT20058000, SMINT20060780, SMINT20065960, SMINT20076470,
SMINT20080540, SMINT20089170, SMINT20092330, SMINT20092720,
SMINT20098320, SMINT20103690, SMINT20105000, SMINT20108530,
SMINT20109970, SMINT20122850, SMINT20132280, SMINT20153530,
SMINT20158100, SMINT20161220, SMINT20162860, SMINT20164400,
SMINT20164770, SMINT20173190, SPLEN10000830, SPLEN20000640,
SPLEN20002220, SPLEN20008820, SPLEN20013540, SPLEN20016260,
SPLEN20019450, SPLEN20020070, SPLEN20022230, SPLEN20023140,
SPLEN20031600, SPLEN20032040, SPLEN20032190, SPLEN20033960,
SPLEN20040600, SPLEN20076530, SPLEN20101190, SPLEN20106250,
SPLEN20129610, SPLEN20146690, SPLEN20149190, SPLEN20152610,
SPLEN20157300, SPLEN20158900, SPLEN20158990, SPLEN20160690,
SPLEN20160980, SPLEN20166270, SPLEN20171210, SPLEN20176200,
SPLEN20193110, SPLEN20198110, SPLEN20204170, SPLEN20212950,
SPLEN20214400, SPLEN20225220, SPLEN20242320, SPLEN20242730,
SPLEN20249560, SPLEN20261440, SPLEN20264110, SPLEN20279950,
SPLEN20280660, SPLEN20303970, STOMA20013890, STOMA20026880,
STOMA20036460, STOMA20048520, STOMA20048840, STOMA20062290,
STOMA20067800, STOMA20072690, STOMA20076800, STOMA20086140,
STOMA20092560, SYNOV20003970, TCOLN20001390, TESOP20000900,
TESOP20003120, TESTI10000940, TESTI20004890, TESTI20011200,
TESTI20018230, TESTI20029930, TESTI20030310, TESTI20030890,
TESTI20038270, TESTI20066770, TESTI20076850, TESTI20086210,
TESTI20087620, TESTI20094020, TESTI20098530, TESTI20102800,
TESTI20105720, TESTI20112940, TESTI20114070, TESTI20116650,
TESTI20122310, TESTI20129150, TESTI20129220, TESTI20130120,
TESTI20135660, TESTI20136990, TESTI20137370', TESTI20137670,
TESTI20143240, TESTI20143620, TESTI20155900, TESTI20157100,
TESTI20159140, TESTI20161970, TESTI20168630, TESTI20168960,
TESTI20169960, TESTI20171020, TESTI20178160, TESTI20179320,
TESTI20183370, TESTI20185810, TESTI20192280, TESTI20194300,
TESTI20194810, TESTI20199170, TESTI20200260, TESTI20203440,
TESTI20209460, TESTI20211240, TESTI20213150, TESTI20213580,
TESTI20220100, TESTI20220650, TESTI20224620, TESTI20226490,
TESTI20234270, TESTI20238000, TESTI20239470, TESTI20240090,
TESTI20241530, TESTI20241920, TESTI20244760, TESTI20262330,
TESTI20262910, TESTI20265250, TESTI20265370, TESTI20269570,
TESTI20272060, TESTI20272390, TESTI20275620, TESTI20277360,
TESTI20278200, TESTI20280980, TESTI20282540, TESTI20285830,
TESTI20288110, TESTI20289850, TESTI20291620, TESTI20294700,
TESTI20297850, TESTI20301360, TESTI20305560, TESTI20307540,
TESTI20310070, TESTI20311290, TESTI20319190, TESTI20327740,
TESTI20330310, TESTI20333950, TESTI20336410, TESTI20337100,
TESTI20342430, TESTI20345060, TESTI20347740, TESTI20347770,
TESTI20357750, TESTI20357930, TESTI20361140, TESTI20367360,
TESTI20369130, TESTI20369220, TESTI20370550, TESTI20371060,
TESTI20378450, TESTI20380650, TESTI20386230, TESTI20386440,
TESTI20388580, TESTI20391130, TESTI20392090, TESTI20401430,
TESTI20406420, TESTI20409440, TESTI20413300, TESTI20415640,
TESTI20419560, TESTI20423020, TESTI20424000, TESTI20424730,
TESTI20425070, TESTI20427830, TESTI20428060, TESTI20429280,
TESTI20429580, TESTI20433130, TESTI20438660, TESTI20447540,
TESTI20451710, TESTI20458190, TESTI20465520, TESTI20468630,
TESTI20471470, TESTI20471530, TESTI20472120, TESTI20473420,
TESTI20477920, TESTI20478010, TESTI20478180, TESTI20479300,
THYMU20000570, THYMU20011950, THYMU20015210, THYMU20018190,
THYMU20029100, THYMU20045120, THYMU20058070, THYMU20061700,
THYMU20070360, THYMU20075320, THYMU20095960, THYMU20101610,
THYMU20101920, THYMU20111420, THYMU20114470, THYMU20118060,
THYMU20119390, THYMU20128070, THYMU20128260, THYMU20142970,
THYMU20153160, THYMU20158250, THYMU20186390, THYMU20186730,
THYMU20187720, THYMU20195990, THYMU20204160, THYMU20204990,
THYMU20215090, THYMU20215970, THYMU20226600, THYMU20228540,
THYMU20235760, THYMU20239430, THYMU20246840, THYMU20250420,
THYMU20251890, THYMU20253250, THYMU20255570, THYMU20255720,
THYMU20259090, THYMU20265300, THYMU20271250, THYMU20272490,
THYMU20283790, THYMU20284120, THYMU20286290, THYMU20286320,
TKIDN20030590, TKIDN20030620, TOVAR20005750, TRACH20027840,
TRACH20032720, TRACH20037360, TRACH20056980, TRACH20060150,
TRACH20082780, TRACH20091230, TRACH20092680, TRACH20099340,
TRACH20107710, TRACH20115740, TRACH20118940, TRACH20147250,
TRACH20153810, TRACH20169800, TRACH20187180, TSTOM10001860,
TSTOM20001390, TSTOM20003150, UMVEN20003540, UTERU20006290,
UTERU20020010, UTERU20054460, UTERU20056010, UTERU20059050,
UTERU20061030, UTERU20067050, UTERU20068990, UTERU20070040,
UTERU20070810, UTERU20081300, UTERU20084260, UTERU20095380,
UTERU20095400, UTERU20101240, UTERU20114100, UTERU20118110,
UTERU20118970, UTERU20119680, UTERU20124070, UTERU20126880,
UTERU20134910, UTERU20143980, UTERU20146680, UTERU20150870,
UTERU20164260, UTERU20188810
EXAMPLE 7
Expression Frequency Analysis in Silico
[0499] The cDNA libraries derived from various tissues and cells as
indicated in Example 1 were prepared, and cDNA clones were selected
from each library at random. The 5'-end sequences were determined
and the database was constructed based on the data. The database
was constructed based on the nucleotide sequences of 1,402,070
clones, and thus the population of the database is large enough for
the analysis.
[0500] Then, clones having a homologous sequence are categorized
into a single cluster (clustering) by searching the nucleotide
sequences of respective clones in this database with the program of
nucleotide sequence homology search; the number of clones belonging
to each cluster was determined and normalized for every library;
thus, the ratio of a certain gene in each cDNA library was
determined. This analysis gave the information of the expression
frequency of genes in tissues and cells which were sources of the
cDNA libraries.
[0501] Then, in order to analyze the expression of a gene
containing the nucleotide sequence of the cDNA of the present
invention in tissues and cells, the library derived from a tissue
or a cell used in the large-scale cDNA analysis was subjected to
the comparison of the expression levels between tissues or cells.
Namely, the expression frequency was analyzed by comparing the
previously normalized values between tissues and/or cells for which
the nucleotide sequences of 600 or more cDNA clones had been
analyzed. By this analysis, some of the genes were revealed to be
involved in the pathology and functions indicated below. Each value
in Tables 3 to 51 shown below represents a relative expression
frequency; the higher the value, the higher the expression
level.
Osteoporosis-Related Genes
[0502] Osteoporosis is a pathology in which bones are easily broken
owing to overall decrease in components of bone. The onset involves
the balance between the functions of osteoblast producing bone and
osteoclast absorbing bone, namely bone metabolism. Thus, the genes
involved in the increase of osteoclasts differentiating from
precursor cells of monocyte/macrophage line (Molecular Medicine 38.
642-648. (2001)) are genes involved in osteoporosis relevant to
bone metabolism.
[0503] A nucleotide sequence information-based analysis was carried
out to identify the genes whose expression frequencies are higher
or lower in CD34+ cell (cell expressing a glycoprotein CD34)
treated with the osteoclast differentiation factor (Molecular
Medicine 38. 642-648. (2001)) than in the untreated CD34+ cell,
which is the precursor cell of monocyte/macrophage line. The result
of comparative analysis for the frequency between the two cDNA
libraries prepared from the RNA of CD34+ cells (CD34C) and from the
RNA of CD34+ cells treated with the osteoclast differentiation
factor (D30ST, D60ST or D90ST) showed that the genes whose
expression levels were different between the two were the following
clones (Table 3).
[0504] ASTRO20001410, D30ST10001090, D30ST20036070, THYMU20039810,
KIDNE20028720, BRAWH10000930, BRHIP20005340, CTONG20141650,
D9OST20000310, D90ST20002780, D90ST20023970, D90ST20026730,
D9OST20031370, D9OST20033970, D9OST20035800, D9OST20035940,
D9OST20040180, FCBBF30018550, FCBBF30233680, KIDNE20102650,
NT2RI20023160, PROST20107820, SKNSH20089400, SMINT20033400,
CTONG20108210, D60ST20003580, D60ST20005070, ASTRO20155290,
D3OST10002670, D3OST10002700, D3OST20006180, D3OST20006540,
D3OST20007340, D3OST20013280, D3OST20024170, D3OST20024360,
D3OST20037970, D3OST30002580, D3OST30002910, FCBBF10004120,
NT2RI20001330, NTONG20009770, SPLEN20084600, SPLEN20140800,
THYMU20169680, TRACH20141240, CD34C30001250, CD34C30003140,
CD34C30004240, CD34C30004940, DFNES10001850, HHDPC20034390,
NT2RI20091730, SKMUS20003610, SPLEN20225220, BRCOC20101230
[0505] These genes are involved in osteoporosis.
[0506] Genes involved in neural cell differentiation
[0507] Genes involved in neural cell differentiation are useful for
treating neurological diseases. Genes with varying expression
levels in response to induction of cellular differentiation in
neural cells are thought to be involved in neurological
diseases.
[0508] A survey was performed for genes whose expression levels are
varied in response to induction of differentiation (stimulation by
retinoic acid (RA) or growth inhibitor treatment after RA
stimulation) in cultured cells of a neural strain, NT2. The result
of comparative analysis of cDNA libraries derived from
undifferentiated NT2 cells (NT2RM) and the cells subjected to the
differentiation treatment (NT2RP, NT2R1 or NT2NE) showed that the
genes whose expression levels were different between the two were
the following clones (Table 4).
[0509] CTONG20027090, CTONG20160560, NT2RP70032610, OCBBF20188730,
SPLEN20162680, BRCOC20101230, BRHIP20005340, BRHIP20238880,
FCBBF30016320, FEBRA20080810, FEBRA20225040, HCHON20008320,
HHDPC20034390, HLUNG10000550, NT2RI20028470, NT2RI20054050,
NT2RI20091730, NT2RP70078420, PUAEN20003740, THYMU20271250,
BRACE20003070, BRACE20039040, BRAWH20004600, BRAWH20011710,
BRCOC20121720, BRHIP20005530, D3OST10002700, HCHON20007380,
HEART20072310, KIDNE20121880, MESAN20121130, NT2RI20022600,
NT2RI20023160, NT2RI20086220, NT2RI20216250, NT2RP60000850,
NT2RP70036880, NT2RP70043480, NT2RP70062230, NT2RP70081610,
NT2RP70102350, NT2RP70130020, NT2RP70190640, OCBBF10001850,
OCBBF20097720, OCBBF20173980, PEBLM20044520, SPLEN20173510,
TRACH20007020, UTERU20065930, HCHON20022470, NT2NE20010490,
NT2NE20174800, NT2NE20177520, PROST20087700, PROST20107820,
SMINT20028820, TESTI20063830, ASTRO20125520, BRHIP30001110,
HCHON20002260, HCHON20008150, KIDNE20002520, NT2NE20130190,
NT2NE20158600, NT2RI20001330, NT2RI20025400, NT2RI20036670,
NT2RI20048840, SKMUS20020840, BRACE20057190, BRACE20060550,
BRACE20267250, BRAWH20107540, BRAWH20118230, CTONG20075860,
CTONG20095290, FEBRA20086620, FEBRA20144170, FEBRA20196370,
HLUNG20023340, NT2NE20003740, NT2NE20010050, NT2NE20010210,
NT2NE20010400, NT2NE20015240, NT2NE20021620, NT2NE20043780,
NT2NE20053580, NT2NE20068130, NT2NE20072200, NT2NE20074250,
NT2NE20080170, NT2NE20089610, NT2NE20089970, NT2NE20108540,
NT2NE20110360, NT2NE20118960, NT2NE20122430, NT2NE20124480,
NT2NE20125050, NT2NE20131890, NT2NE20132170, NT2NE20142210,
NT2NE20146810, NT2NE20152750, NT2NE20155110, NT2NE20156260,
NT2NE20157470, NT2NE20159740, NT2NE20172590, NT2NE20174920,
NT2NE20181650, NT2NE20183760, NT2NE20184900, NT2NE20187390,
OCBBF20108430, RECTM20005100, SMINT20001760, SPLEN20169720,
TESTI20265250, ASTRO10001650, ASTRO20033160, BRACE20011070,
BRACE20039440, BRACE20151320, BRAMY20104640, BRAMY20137560,
BRAMY20167060, BRAWH20028110, BRCAN20280360, BRCOC20004870,
BRHIP20207990, BRHIP20217620, BRHIP20249110, BRSTN10000830,
CTONG10000940, CTONG20004690, CTONG20050280, CTONG20105660,
CTONG20125640, CTONG20133520, CTONG20186320, FCBBF10000770,
FCBBF10002800, FCBBF10003770, FCBBF30018550, FCBBF30123470,
FCBBF30246230, FEBRA20018280, FEBRA20095140, FEBRA20192420,
HCHON20064590, HHDPC10000830, HLUNG20016770, HLUNG20033780,
IMR3220002430, KIDNE20104300, MESAN20004570, MESAN20089360,
NOVAR10000910, NT2RI20003480, NT2RI20005750, NT2RI20009870,
NT2RI20023590, NT2RI20023910, NT2RI20025640, NT2RI20040930,
NT2RI20041880, NT2RI20046080, NT2RI20050960, NT2RI20055790,
NT2RI20056700, NT2RI20069730, NT2RI20076290, NT2RI20091940,
NT2RI20198260, NT2RI20203900, NT2RI20207030, NT2RI20240080,
NT2RI20244600, NT2RI20244960, NT2RI20250750, NT2RI20252550,
NT2RI20273230, NTONG20067090, OCBBF10001750, OCBBF20047570,
OCBBF20054760, OCBBF20059560, OCBBF20073540, OCBBF20125530,
OCBBF20126780, OCBBF20127040, OCBBF20140890, SKMUS20003610,
SKNSH20008190, SKNSH20080430, SMINT20144800, SPLEN20027440,
SPLEN20095550, SPLEN20140800, TESTI20094020, TESTI20369690,
TESTI20391770, TESTI20442760, TRACH20084720, TRACH20107710,
TRACH20118940, UTERU20022940, ASTRO20108190, BGGI120006160,
BRAMY20136210, BRAWH20016620, BRAWH20164460, BRCOC20144000,
BRHIP20132860, BRSSN20146100, CTONG10000100, CTONG20103480,
CTONG20108210, CTONG20139070, FCBBF10000240, FCBBF10000630,
FCBBF20067810, FCBBF30010810, FCBBF30012810, FCBBF30013770,
FCBBF30039020, FCBBF40001420, FEBRA10001880, FEBRA20082010,
HHDPC20001040, KIDNE20021910, NT2RP60000770, NT2RP70010740,
NT2RP70027380, NT2RP70037240, NT2RP70044280, NT2RP70045590,
NT2RP70056750, NT2RP70063950, NT2RP70072690, NT2RP70077660,
NT2RP70085440, NT2RP70105210, NT2RP70110860, NT2RP70111320,
NT2RP70122910, NT2RP70125160, NT2RP70133740, NT2RP70134990,
NT2RP70137290, NT2RP70137640, NT2RP70143480, NT2RP70147210,
NT2RP70150800, NT2RP70157890, NT2RP70159960, NT2RP70169110,
NT2RP70175670, NT2RP70179710, NT2RP70181970, NT2RP70188020,
NT2RP70188710, NT2RP70192730, NT2RP70194450, NT2RP70195430,
NT2RP70198350, NT2RP70203790, OCBBF20039250, OCBBF20080410,
OCBBF20108190, OCBBF20108580, OCBBF20122620, OCBBF20130110,
OCBBF20151150, OCBBF20189560, PROST10003220, TESTI20001720,
TESTI20121550, TESTI20152460, TESTI20211240, TESTI20234140,
UMVEN20003540, UTERU20006960, UTERU20094350, UTERU20164260
[0510] These genes are neurological disease-related genes.
Cancer-related genes
[0511] It has been assumed that, distinct from normal tissues,
cancer tissues express a distinct set of genes, and thus the
expression can contribute to the carcinogenesis in tissues and
cells. Thus, the genes whose expression patterns in cancer tissues
are different from those in normal tissues are cancer-related
genes. Search was carried out for the genes whose expression levels
in cancer tissues were different from those in normal tissues.
[0512] The result of comparative analysis of cDNA libraries derived
from breast tumor (TBAES) and normal breast (BEAST) showed that the
genes whose expression levels were different between the two were
the following clones (Table 5).
[0513] BRACE20039040, BRAMY20163250, BRCOC20031250, BRHIP20005340,
BRHIP20217620, BRHIP30001110, FCBBF10000770, FCBBF30010810,
FEBRA20080810, FEBRA20144170, FEBRA20196630, FEBRA20197110,
HCHON20002260, HCHON20040020, HHDPC20034390, HLUNG10000550,
NOVAR10000910, NT2RI20023160, NT2RI20054050, NT2RI20091730,
OCBBF20188730, SMINT20144800, SPLEN20128000, SPLEN20171210,
SPLEN20264110, TBAES20000590, TBAES20002550, TBAES20003150,
TESTI20334410, TESTI20432750, TRACH20003590, TRACH20084720,
UTERU20046640, BEAST20004540, SPLEN20008740
[0514] The result of comparative analysis of cDNA libraries derived
cervical tumor (TCERX) and normal cervical duct (CERVX) showed that
the genes whose expression levels were different between the two
were the following clones (Table 6).
BGGI120006160, BRAMY20063970, BRHIP20218580, FEBRA20002100,
SPLEN20162680, TESTI20214250, CTONG20105080, HCHON20015980,
PROST20175290, TESTI20254220, THYMU20279750
[0515] The result of comparative analysis of cDNA libraries derived
from colon tumor (TCOLN) and normal colon (COLON) showed that the
genes whose expression levels were different between the two were
the following clones (Table 7).
[0516] ASTRO20001410, BRAWH20162690, CTONG20132220, HCHON20002260,
NT2RI20001330, TCOLN20001390, 3NB6910001910, BRAMY20120910,
BRAWH20004600, BRCOC20031250, BRCOC20031870, COLON10001350,
COLON20043180, COLON20093370, FEBRA20002100, FEBRA20082010,
FEBRA20197110, KIDNE20007770, KIDNE20013730, NT2RP70045590,
OCBBF20078920, PROST20083600, SPLEN20011410, TRACH20084720,
THYMU20271250
[0517] The result of comparative analysis of cDNA libraries derived
from esophageal tumor (TESOP) and normal esophagus (NESOP) showed
that the genes whose expression levels were different between the
two were the following clones (Table 8).
[0518] ASTRO20033160, ASTRO20125520, BRAMY20266850, BRAWH20164460,
BRHIP20005340, BRHIP20191490, CTONG20095290, CTONG20143690,
CTONG20161850, DFNES20001530, DFNES20071130, FCBBF30123470,
FCBBF30175310, FEBRA20095140, HCHON20016650, MESAN20025190,
NT2RI20028470, NT2RI20054050, NT2RP70036880, NTONG20009770,
NTONG20064840, NTONG20076930, SMINT20042990, SPLEN20008820,
SPLEN20128000, SPLEN20149110, STOMA20013890, TESOP20000900,
TESOP20003120, TESOP20004000, TESOP20005270, TESOP20005690,
TESTI20334410, THYMU20271250, TRACH20141240, UTERU20022940,
NESOP10001080, NT2RI20023160, NTONG20013620, TRACH20077540,
NTONG20015870
[0519] The result of comparative analysis of cDNA libraries derived
from kidney tumor (TKIDN) and normal kidney (KIDNE) showed that the
genes whose expression levels were different between the two were
the following clones (Table 9).
[0520] ASTRO20008010, ASTRO20181690, BRACE20111830, BRACE20152870,
BRACE20237270, BRAMY20147540, BRAMY20286820, BRAWH20015350,
BRAWH20096780, BRAWH20132190, BRAWH20182060, BRCAN20060190,
BRCOC20004870, BRCOC20176520, BRHIP20000870, BRHIP20198190,
BRHIP20233090, BRHIP30001110, BRSSN20015790, BRSTN20000580,
CTONG10000940, CTONG20098440, CTONG20150910, CTONG20165050,
DFNES20014040, DFNES20037420, FCBBF10000770, FCBBF30083820,
FCBBF30247930, FEBRA20037500, FEBRA20072120, FEBRA20080810,
FEBRA20086620, FEBRA20140100, FEBRA20144170, FEBRA20176800,
HCHON20008320, HCHON20059870, HLUNG10000550, MESAN20106640,
NT2RI20025400, NT2RI20076290, NT2RI20091940, OCBBF20019830,
OCBBF20022900, OCBBF20039250, OCBBF20080050, OCBBF20097720,
OCBBF20125530, OCBBF20130110, OCBBF20140640, OCBBF20173980,
PANCR10000910, PROST20087700, PUAEN20044000, SPLEN20144520,
SPLEN20160980, TKIDN10000010, TKIDN20004640, TKIDN20005210,
TKIDN20030590, TKIDN20030620, TKIDN20047480, TRACH20003590,
TRACH20028030, TRACH20183170, TRACH20184490, UMVEN20003540,
UTERU20004240, UTERU20055930, ASTRO10001650, ASTRO20108190,
BGGI120006160, BRACE20039040, BRAMY20102080, BRAWH20004600,
BRAWH20125380, BRAWH20162690, BRHIP20115760, BRHIP20205090,
CTONG20052650, CTONG20108210, CTONG20128470, CTONG20133480,
CTONG20139070, D90ST20000310, DFNES20001530, FCBBF10001820,
FEBRA20002100, HCHON20008980, HCHON20016650, HLUNG20033780,
KIDNE20002520, KIDNE20003940, KIDNE20006780, KIDNE20007210,
KIDNE20007770, KIDNE20008010, KIDNE20009470, KIDNE20011170,
KIDNE20011400, KIDNE20013730, KIDNE20017130, KIDNE20018730,
KIDNE20018970, KIDNE20020150, KIDNE20021680, KIDNE20021910,
KIDNE20021980, KIDNE20022620, KIDNE20024830, KIDNE20027250,
KIDNE20027950, KIDNE20028390, KIDNE20028720, KIDNE20028830,
KIDNE20029800, KIDNE20067330, KIDNE20079440, KIDNE20096280,
KIDNE20096470, KIDNE20100070, KIDNE20100840, KIDNE20101370,
KIDNE20101510, KIDNE20102650, KIDNE20102710, KIDNE20104300,
KIDNE20106740, KIDNE20107390, KIDNE20107500, KIDNE20107620,
KIDNE20109730, KIDNE20109890, KIDNE20112000, KIDNE20115080,
KIDNE20118580, KIDNE20120090, KIDNE20121880, KIDNE20122910,
KIDNE20124400, KIDNE20125630, KIDNE20126010, KIDNE20126130,
KIDNE20127100, KIDNE20127450, KIDNE20127750, KIDNE20130450,
KIDNE20131580, KIDNE20132180, KIDNE20137340, KIDNE20138010,
KIDNE20141190, KIDNE20144890, KIDNE20148900, KIDNE20163880,
KIDNE20180710, KIDNE20181660, KIDNE20182690, KIDNE20186780,
KIDNE20190740, LIVER20035110, MESAN20025190, NT2RP70043480,
PROST20107820, PROST20123530, PROST20161950, PUAEN20030180,
SKMUS20003610, SMINT20033400, TBAES20000590, TESTI20044310,
TESTI20082330, TRACH20032720, UTERU20099720
[0521] The result of comparative analysis of cDNA libraries derived
from liver tumor (TLIVE) and normal liver (LIVER) showed that the
genes whose expression levels were different between the two were
the following clones (Table 10).
[0522] BRAWH20166790, CTONG20103480, HEART20005410, LIVER10001260,
LIVER10004790, LIVER20002160, LIVER20011130, LIVER20011910,
LIVER20028420, LIVER20035110, LIVER20035680, LIVER20038540,
LIVER20045650, LIVER20055200, LIVER20055440, LIVER20059810,
LIVER20062510, LIVER20064100, LIVER20064690, LIVER20075680,
LIVER20080530, LIVER20084730, LIVER20085800, LIVER20087510,
LIVER20091180, NTONG20063010, PROST20087700, PROST20107820,
TRACH20005400, ASTRO20001410, ASTRO20125520, BRACE20152870,
BRAMY20167060, BRAMY20181220, BRAMY20285160, BRCOC20001860,
FEBRA20144170, HLUNG10000550, OCBBF20073540, OCBBF20088220,
PLACE60169420, SMINT20152940, SPLEN20242320, THYMU20000570,
TRACH20077540, UTERU20055930, UTERU20065930
[0523] The result of comparative analysis of cDNA libraries derived
from lung tumor (TLUNG) and normal lung (HLUNG) showed that the
genes whose expression levels were different between the two were
the following clones (Table 11).
[0524] BRACE20096200, BRAWH20004600, BRAWH20030250, BRCAN20006390,
BRCAN20280360, BRHIP20238880, CTONG10000940, CTONG20103480,
CTONG20129960, CTONG20155180, FCBBF10001210, FEBRA20144170,
FEBRA20197110, HCHON20002260, HHDPC20034390, HLUNG10000550,
HLUNG20016330, HLUNG20016770, HLUNG20017120, HLUNG20023340,
HLUNG20033780, HLUNG20084390, IMR3220002430, LIVER20028420,
NOVAR20000380, NT2RI20023910, NT2RI20054050, NT2RI20091730,
NT2RP70044280, OCBBF20020830, OCBBF20125530, PLACE60004630,
PROST20057930, PROST20107820, PROST20185830, PUAEN20030180,
SMINT20121220, SPLEN20002220, SPLEN20008740, SPLEN20054290,
SPLEN20128000, SPLEN20157300, SPLEN20176200, SPLEN20179180,
SPLEN20211940, STOMA20013890, TBAES20000590, TESTI20094230,
TESTI20184620, TESTI20334410, THYMU20000570, THYMU20039810,
TRACH20007020, TRACH20141240, TRACH20183170, ASTRO20108190,
ASTRO20155290, BRHIP20096850, FEBRA20080810, MESAN20014500,
SMINT20028820, SPLEN20162680
[0525] The result of comparative analysis of cDNA libraries derived
from ovary tumor (TOVER) and normal ovary (NOVER) showed the genes
whose expression levels were different between the two were the
following clones (Table 12).
[0526] BGGI120006160, BRHIP20005340, BRHIP20191860, HHDPC20001040,
NOVAR10000150, NOVAR10000910, NOVAR10001020, NOVAR20000380,
NOVAR20003520, THYMU20271250, ASTRO20141350, BRAMY20157820,
BRCOC20001860, HLUNG20016770, NT2RI20054050, NTONG20090600,
PROST20087700, PUAEN20015860, SPLEN20029310, TOVAR20004760,
TOVAR20005750, TRACH20079690, UTERU20004240
[0527] The result of comparative analysis of cDNA libraries derived
from stomach tumor (TSTOM) and normal stomach (STOMA) showed that
the genes whose expression levels were different between the two
were the following clones (Table 13).
[0528] BRACE20060840, FEBRA20052910, HCHON20002260, HLUNG10000550,
NTONG20009770, PROST20107820, THYMU20039810, TSTOM10001860,
TSTOM20001390, TSTOM20003150, TSTOM20005690, ASTRO20125520,
BRACE20039040, BRAMY20124260, BRCOC20031870, BRHIP20191860,
CTONG20128470, FEBRA20037500, HCHON20040020, HHDPC10000830,
IMR3220002430, KIDNE20007770, NOVAR20000380, NT2RI20054050,
NT2RI20091730, PROST20130530, SPLEN20149110, SPLEN20157880,
STOMA20001830, STOMA20005390, STOMA20005670, STOMA20006400,
STOMA20006780, STOMA20006860, STOMA20008880, STOMA20010250,
STOMA20013890, STOMA20026880, STOMA20032890, STOMA20034770,
STOMA20036460, STOMA20046680, STOMA20048520, STOMA20048840,
STOMA20051200, STOMA20056640, STOMA20056670, STOMA20057820,
STOMA20062130, STOMA20062290, STOMA20063250, STOMA20063980,
STOMA20064470, STOMA20067800, STOMA20069040, STOMA20072690,
STOMA20076800, STOMA20077450, STOMA20080500, STOMA20083610,
STOMA20086140, STOMA20088380, STOMA20092530, STOMA20092560,
STOMA20092890, TESTI20184620, TRACH20003590, TRACH20183170,
PROST20083600, TRACH20068660
[0529] The result of comparative analysis of cDNA libraries derived
from uterine tumor (TUTER) and normal uterus (UTERU) showed that
the genes whose expression levels were different between the two
were the following clones (Table 14). DFNES10001850, NT2RI20023910,
SMINT20144800, SPLEN20162680, TOVAR20004760, TUTER20002830,
ASTRO20008010, ASTRO20033160, ASTRO20058630, ASTRO20105820,
ASTRO20108190, BRACE20039040, BRACE20057190, BRACE20060840,
BRACE20111830, BRACE20223330, BRAMY20266850, BRAWH20113430,
BRAWH20126980, BRCOC20031870, BRCOC20107300, BRCOC20121720,
BRCOC20155970, BRHIP20105710, BRHIP20191490, BRHIP20207990,
BRHIP20217620, BRHIP20222280, BRHIP20238880, BRHIP20249110,
BRSSN20018690, BRTHA20000570, CTONG10000940, CTONG10002770,
CTONG20095290, CTONG20099380, CTONG20103480, CTONG20108210,
CTONG20118250, CTONG20129960, CTONG20131560, CTONG20139070,
CTONG20139340, CTONG20143690, CTONG20160560, D30ST30002580,
FCBBF10000240, FCBBF10001820, FCBBF10003670, FCBBF10004120,
FCBBF10005740, FCBBF30175310, FCBBF30240020, FCBBF30246230,
FCBBF40001420, FEBRA20002100, FEBRA20004620, FEBRA20018280,
FEBRA20025270, FEBRA20034360, FEBRA20037500, FEBRA20080810,
FEBRA20082100, FEBRA20144170, FEBRA20225040, HCHON20002260,
HCHON20007380, HCHON20015980, HCHON20016650, HCHON20022470,
HCHON20040020, HCHON20076500, HEART20072310, HHDPC20034390,
HLUNG10000550, HLUNG20016770, KIDNE20131580, LIVER20028420,
MAMGL10000830, MESAN20171520, NOVAR10000150, NOVAR10000910,
NT2NE20053580, NT2NE20159740, NT2NE20174920, NT2RI20023160,
NT2RI20041880, NT2RI20054050, NT2RI20076290, NT2RI20273230,
NT2RP60000770, NT2RP60000850, NT2RP70036880, NT2RP70043480,
NT2RP70045590, NT2RP70056750, NT2RP70062230, NT2RP70081610,
OCBBF10001750, OCBBF20006770, OCBBF20032460, OCBBF20039250,
OCBBF20047570, OCBBF20054760, OCBBF20059560, OCBBF20068490,
OCBBF20080050, OCBBF20094240, OCBBF20097720, OCBBF20103130,
OCBBF20105570, OCBBF20140640, OCBBF20173980, OCBBF20180120,
OCBBF20188730, OCBBF20189560, PEBLM20044520, PLACE60060420,
PROST20087700, PROST20107820, PROST20149160, PROST20159240,
PROST20176170, PROST20189770, PUAEN20003740, PUAEN20015860,
SKMUS20003610, SKNSH20008190, SKNSH20080430, SMINT20026890,
SMINT20029760, SMINT20068010, SMINT20110330, SMINT20121220,
SPLEN20008390, SPLEN20011410, SPLEN20054290, SPLEN20128000,
SPLEN20140800, SPLEN20145720, SPLEN20169720, SPLEN20179180,
SPLEN20193110, SPLEN20194050, SPLEN20211940, SPLEN20212730,
SPLEN20225220, TBAES20000590, TESTI20061110, TESTI20116830,
TESTI20184620, TESTI20208710, TESTI20211240, TESTI20213580,
TESTI20214250, TESTI20334410, TESTI20369130, TESTI20369690,
TESTI20391770, THYMU20039810, THYMU20216840, THYMU20240710,
TRACH20003590, TRACH20032720, TRACH20033230, TRACH20141240,
TRACH20149970, UMVEN10001860, UTERU20000740, UTERU20004240,
UTERU20006290, UTERU20020010, UTERU20022940, UTERU20030570,
UTERU20040610, UTERU20046640, UTERU20046980, UTERU20050690,
UTERU20054460, UTERU20055330, UTERU20055930, UTERU20056010,
UTERU20059050, UTERU20061030, UTERU20064000, UTERU20064860,
UTERU20065930, UTERU20067050, UTERU20068990, UTERU20070040,
UTERU20070810, UTERU20076390, UTERU20081300, UTERU20084260,
UTERU20094350, UTERU20095380, UTERU20095400, UTERU20097760,
UTERU20099720, UTERU20101240, UTERU20114100, UTERU20115740,
UTERU20116570, UTERU20118110, UTERU20118970, UTERU20119060,
UTERU20119680, UTERU20120310, UTERU20124070, UTERU20126880,
UTERU20134910, UTERU20135860, UTERU20143980, UTERU20144640,
UTERU20145480, UTERU20146310, UTERU20146680, UTERU20150870,
UTERU20151980, UTERU20158300, UTERU20158800, UTERU20161570,
UTERU20164260, UTERU20168220, UTERU20176130, UTERU20176320,
UTERU20178100, UTERU20179880, UTERU20183640, UTERU20185230,
UTERU20186740, UTERU20188110, UTERU20188810, BRAWH10000930,
CTONG20128470, UTERU20006960
[0530] The result of comparative analysis of cDNA libraries derived
from tongue cancer (CTONG) and normal tongue (NTONG) showed that
the genes whose expression levels were different between the two
were the following clones (Table 15).
[0531] ADRGL20018300, ASTRO20058630, ASTRO20072210, ASTRO20108190,
BRACE20003070, BRACE20039040, BRACE20060720, BRACE20061050,
BRACE20210140, BRACE20276430, BRAMY20152110, BRAMY20266850,
BRAMY20271400, BRAWH10000930, BRAWH20004600, BRCAN20280360,
BRCOC20004870, BRHIP20005340, BRHIP20005530, BRHIP20238880,
BRSSN20146100, CTONG10000100, CTONG10000220, CTONG10000620,
CTONG10000930, CTONG10000940, CTONG10001650, CTONG10002770,
CTONG20002180, CTONG20004690, CTONG20009770, CTONG20014280,
CTONG20027090, CTONG20028410, CTONG20038890, CTONG20049410,
CTONG20050280, CTONG20052650, CTONG20052900, CTONG20075860,
CTONG20076130, CTONG20077790, CTONG20082690, CTONG20085950,
CTONG20091080, CTONG20091320, CTONG20092570, CTONG20092580,
CTONG20092680, CTONG20092700, CTONG20093950, CTONG20095270,
CTONG20095290, CTONG20095340, CTONG20096430, CTONG20096750,
CTONG20097660, CTONG20098440, CTONG20099380, CTONG20099550,
CTONG20099630, CTONG20100240, CTONG20101480, CTONG20103480,
CTONG20105080, CTONG20105660, CTONG20106230, CTONG20106520,
CTONG20108210, CTONG20114290, CTONG20114740, CTONG20118150,
CTONG20118250, CTONG20119200, CTONG20120770, CTONG20121010,
CTONG20121580, CTONG20124010, CTONG20124220, CTONG20124470,
CTONG20124730, CTONG20125540, CTONG20125640, CTONG20126070,
CTONG20127450, CTONG20128470, CTONG20129960, CTONG20131490,
CTONG20131560, CTONG20132220, CTONG20133390, CTONG20133480,
CTONG20133520, CTONG20136300, CTONG20138030, CTONG20139070,
CTONG20139340, CTONG20139860, CTONG20140320, CTONG20140580,
CTONG20141650, CTONG20146300, CTONG20147050, CTONG20149460,
CTONG20149950, CTONG20153300, CTONG20153580, CTONG20155180,
CTONG20155400, CTONG20156780, CTONG20158040, CTONG20158150,
CTONG20158660, CTONG20159530, CTONG20160560, CTONG20161850,
CTONG20162170, CTONG20163550, CTONG20164990, CTONG20165050,
CTONG20186320, CTONG20200310, CTONG20265130, CTONG20267700,
CTONG20273610, FCBBF10000240, FCBBF10005740, FCBBF30123470,
FCBBF30233680, FEBRA20025270, FEBRA20037500, HCHON20002260,
HCHON20007380, HCHON20007510, HCHON20015350, HCHON20040020,
HHDPC20034390, HLUNG10000550, KIDNE20002520, KIDNE20009470,
KIDNE20115080, KIDNE20127100, LIVER20028420, MESAN20029400,
NT2RI20023160, NT2RI20023910, NT2RI20091730, NT2RP70043480,
NT2RP70078420, NT2RP70081610, OCBBF20006770, OCBBF20059560,
OCBBF20073540, OCBBF20094240, OCBBF20108580, PEBLM20044520,
PEBLM20071880, PROST20107820, PUAEN20030180, SKNSH20008190,
SMINT20023280, SMINT20089170, SPLEN20179180, TESTI20094020,
TESTI20094230, TESTI20152460, TESTI20184620, TESTI20211240,
TESTI20442760, THYMU20039810, TRACH20028030, TRACH20141240,
TSTOM20003150, UTERU20004240, UTERU20055930, UTERU20065930,
UTERU20119060, UTERU20124070, BRACE20039440, BRACE20068590,
FCBBF30018550, IMR3220002430, KIDNE20028830, NT2RI20028470,
NT2RI20054050, NT2RI20086220, NTONG20009770, NTONG20013620,
NTONG20028070, NTONG20029480, NTONG20029700, NTONG20046140,
NTONG20048060, NTONG20049910, NTONG20050620, NTONG20050860,
NTONG20051530, NTONG20052650, NTONG20056570, NTONG20061870,
NTONG20063010, NTONG20064400, NTONG20064840, NTONG20065010,
NTONG20066460, NTONG20067090, NTONG20067830, NTONG20070200,
NTONG20070340, NTONG20075220, NTONG20076930, NTONG20077560,
NTONG20083650, NTONG20088620, NTONG20090600, NTONG20090680,
NTONG20092290, NTONG20092330, OCBBF20068490, SKMUS20001980,
SMINT20138900, SPLEN20008390, SPLEN20162680, UTERU20134910,
ASTRO20155290, FEBRA20080810, NT2RP70032610, NT2RP70036880,
NTONG20015870, OCBBF20188730, SMINT20122910, SPLEN20099700
[0532] These genes are involved in cancers.
[0533] Further, there is a method to search for genes involved in
development and differentiation: the expression frequency analysis
in which the expression levels of genes are compared between
developing or differentiating tissues and/or cells and adult
tissues and/or cells. The genes involved in tissue development
and/or differentiation are genes participating in tissue
construction and expression of function, and thus are useful genes,
which are available for regenerative medicine aiming at convenient
regeneration of injured tissues.
[0534] Search was carried out for the genes whose expression
frequencies were different between developing and/or
differentiating tissues and/or cells, and adult tissues and/or
cells, by using the information of gene expression frequency based
on the database of the nucleotide sequences of 1,402,070 clones
shown above.
[0535] The result of comparative analysis of cDNA libraries derived
from fetal brain (FCBBF, FEBRA or OCBBF) and adult brain (BRACE,
BRALZ, BRAMY, BRAWH, BRCAN, BRCOC, BRHIP, BRSSN, BRSTN or BRTHA)
showed that the genes whose expression levels were different
between the two were the following clones (Tables 16 to 48).
3NB6910001910, ADRGL20018300, ASTRO20001410, ASTRO20033160,
ASTRO20058630, ASTRO20064750, ASTRO20100720, ASTRO20141350,
ASTRO20145760, ASTRO20181690, BGGI120006160, BRACE20006400,
BRACE20011070, BRACE20019540, BRACE20027620, BRACE20037660,
BRACE20038000, BRACE20038470, BRACE20038480, BRACE20038850,
BRACE20039440, BRACE20039540, BRACE20050900, BRACE20051380,
BRACE20051690, BRACE20052160, BRACE20053280, BRACE20053480,
BRACE20053630, BRACE20054500, BRACE20055180, BRACE20057420,
BRACE20057620, BRACE20057730, BRACE20058580, BRACE20058810,
BRACE20060840, BRACE20060890, BRACE20061050, BRACE20061740,
BRACE20062400, BRACE20062740, BRACE20063630, BRACE20063780,
BRACE20063800, BRACE20063930, BRACE20064880, BRACE20068590,
BRACE20069090, BRACE20081720, BRACE20082950, BRACE20096200,
BRACE20096540, BRACE20097320, BRACE20101700, BRACE20101710,
BRACE20106840, BRACE20107530, BRACE20108130, BRACE20108880,
BRACE20109370, BRACE20109830, BRACE20114780, BRACE20115450,
BRACE20115920, BRACE20116110, BRACE20116460, BRACE20118380,
BRACE20121850, BRACE20141080, BRACE20142320, BRACE20147800,
BRACE2014.8210, BRACE20148240, BRACE20150310, BRACE20151320,
BRACE20152870, BRACE20153680, BRACE20154120, BRACE20163150,
BRACE20163350, BRACE20165830, BRACE20171240, BRACE20172980,
BRACE20175870, BRACE20177200, BRACE20179340, BRACE20185680,
BRACE20188470, BRACE20190040, BRACE20190440, BRACE20192440,
BRACE20195100, BRACE20201570, BRACE20220300, BRACE20223280,
BRACE20223330, BRACE20224480, BRACE20224500, BRACE20228480,
BRACE20229280, BRACE20230700, BRACE20232840, BRACE20235400,
BRACE20237270, BRACE20238000, BRACE20240740, BRACE20248260,
BRACE20253160, BRACE20253330, BRACE20257100, BRACE20262930,
BRACE20262940, BRACE20266750, BRACE20267250, BRACE20269200,
BRACE20269710, BRACE20273890, BRACE20274080, BRACE20283920,
BRACE20284100, BRACE20286360, BRACE20287410, BRALZ20013500,
BRALZ20014450, BRALZ20017430, BRALZ20018340, BRALZ20054710,
BRALZ20058880, BRALZ20059500, BRALZ20064740, BRALZ20065600,
BRALZ20069760, BRALZ20073760, BRALZ20075450, BRALZ20075760,
BRALZ20077900, BRALZ20077930, BRALZ20080310, BRALZ20088690,
BRAMY10001300, BRAMY10001570, BRAMY20000520, BRAMY20000860,
BRAMY20002770, BRAMY20004110, BRAMY20011140, BRAMY20025840,
BRAMY20039260, BRAMY20045240, BRAMY20054880, BRAMY20060920,
BRAMY20063970, BRAMY20071850, BRAMY20102080, BRAMY20104640,
BRAMY20110640, BRAMY20111960, BRAMY20116790, BRAMY20121190,
BRAMY20121620, BRAMY20124260, BRAMY20134140, BRAMY20135900,
BRAMY20136210, BRAMY20137560, BRAMY20144620, BRAMY20147540,
BRAMY20148130, BRAMY20152110, BRAMY20153110, BRAMY20157820,
BRAMY20160700, BRAMY20163250, BRAMY20163270, BRAMY20167060,
BRAMY20167710, BRAMY20168920, BRAMY20170140, BRAMY20174550,
BRAMY20178640, BRAMY20181220, BRAMY20182730, BRAMY20183080,
BRAMY20184670, BRAMY20195090, BRAMY20204450, BRAMY20205740,
BRAMY20210400, BRAMY20211390, BRAMY20211420, BRAMY20213100,
BRAMY20215230, BRAMY20217460, BRAMY20218250, BRAMY20218670,
BRAMY20229800, BRAMY20229840, BRAMY20230600, BRAMY20231720,
BRAMY20240040, BRAMY20245300, BRAMY20247110, BRAMY20247280,
BRAMY20248490, BRAMY20250240, BRAMY20250320, BRAMY20252180,
BRAMY20252720, BRAMY20260910, BRAMY20261680, BRAMY20266850,
BRAMY20267130, BRAMY20268990, BRAMY20270730, BRAMY20271400,
BRAMY20273960, BRAMY20277140, BRAMY20277170, BRAMY20280720,
BRAMY20284910, BRAMY20285160, BRAMY20285930, BRAMY20286820,
BRAWH20002320, BRAWH20012390, BRAWH20014920, BRAWH20015350,
BRAWH20015890, BRAWH20016660, BRAWH20016860, BRAWH20017010,
BRAWH20018730, BRAWH20028110, BRAWH20029630, BRAWH20064050,
BRAWH20075700, BRAWH20096780, BRAWH20100690, BRAWH20101360,
BRAWH20103180, BRAWH20105840, BRAWH20106180, BRAWH20107540,
BRAWH20110660, BRAWH20110790, BRAWH20110960, BRAWH20111550,
BRAWH20112940, BRAWH20114000, BRAWH20117950, BRAWH20118230,
BRAWH20122580, BRAWH20125380, BRAWH20126190, BRAWH20126980,
BRAWH20132190, BRAWH20137480, BRAWH20138660, BRAWH20139410,
BRAWH20142340, BRAWH20147290, BRAWH20149340, BRAWH20155950,
BRAWH20158530, BRAWH20160280, BRAWH20162690, BRAWH20166790,
BRAWH20171030, BRAWH20173050, BRAWH20182060, BRAWH20185060,
BRCAN10001490, BRCAN20003460, BRCAN20006200, BRCAN20006390,
BRCAN20054490, BRCAN20060190, BRCAN20064010, BRCAN20071190,
BRCAN20091560, BRCAN20103740, BRCAN20124080, BRCAN20126130,
BRCAN20143700, BRCAN20147880, BRCAN20216690, BRCAN20224720,
BRCAN20237240, BRCAN20263400, BRCAN20273100, BRCAN20273340,
BRCAN20273550, BRCAN20275130, BRCAN20279700, BRCAN20280210,
BRCAN20280400, BRCAN20283190, BRCAN20283380, BRCAN2028460b,
BRCAN20285450, BRCOC10000870, BRCOC20001860, BRCOC20004040,
BRCOC20004870, BRCOC20006370, BRCOC20008160, BRCOC20008500,
BRCOC20020850, BRCOC20021550, BRCOC20023230, BRCOC20026640,
BRCOC20027510, BRCOC20031000, BRCOC20031250, BRCOC20031870,
BRCOC20035130, BRCOC20037320, BRCOC20037400, BRCOC20041750,
BRCOC20055420, BRCOC20059510, BRCOC20077690, BRCOC20090520,
BRCOC20091960, BRCOC20093800, BRCOC20099370, BRCOC20101230,
BRCOC20107300, BRCOC20110100, BRCOC20114180, BRCOC20117690,
BRCOC20119960, BRCOC20121720, BRCOC20122290, BRCOC20128130,
BRCOC20134480, BRCOC20135730, BRCOC20136750, BRCOC20144000,
BRCOC20147480, BRCOC20148330, BRCOC20155970, BRCOC20158240,
BRCOC20176520, BRCOC20178560, BRHIP10001290, BRHIP20000870,
BRHIP20001630, BRHIP20096170, BRHIP20096850, BRHIP20103090,
BRHIP20104440, BRHIP20105710, BRHIP20106100, BRHIP20107440,
BRHIP20111200, BRHIP20115080, BRHIP20115760, BRHIP20118380,
BRHIP20118910, BRHIP20119330, BRHIP20121410, BRHIP20123140,
BRHIP20129720, BRHIP20132860, BRHIP20135100, BRHIP20137230,
BRHIP20139720, BRHIP20140630, BRHIP20142850, BRHIP20143730,
BRHIP20143860, BRHIP20149540, BRHIP20153560, BRHIP20153600,
BRHIP20167880, BRHIP20169680, BRHIP20169900, BRHIP20170100,
BRHIP20173150, BRHIP20174040, BRHIP20175420, BRHIP20180140,
BRHIP20183690, BRHIP20186120, BRHIP20186500, BRHIP20189980,
BRHIP20190070, BRHIP20191490, BRHIP20191770, BRHIP20194940,
BRHIP20195890, BRHIP20196410, BRHIP20205090, BRHIP20207430,
BRHIP20207990, BRHIP20208420, BRHIP20208590, BRHIP20227080,
BRHIP20230710, BRHIP20232290, BRHIP20233090, BRHIP20234380,
BRHIP20236950, BRHIP20238600, BRHIP20238690, BRHIP20240460,
BRHIP20243470, BRHIP20249110, BRHIP20252450, BRHIP20253660,
BRHIP20277620, BRHIP20283030, BRHIP20284800, BRHIP20285830,
BRHIP20285930, BRHIP30004880, BRSSN10000920, BRSSN20013420,
BRSSN20014260, BRSSN20015030, BRSSN20015790, BRSSN20018690,
BRSSN20028570, BRSSN20038200, BRSSN20038410, BRSSN20039370,
BRSSN20043040, BRSSN20046570, BRSSN20046790, BRSSN20046860,
BRSSN20066110, BRSSN20097020, BRSSN20101100, BRSSN20105870,
BRSSN20105960, BRSSN20108300, BRSSN20120810, BRSSN20121030,
BRSSN20137020, BRSSN20142940, BRSSN20146100, BRSSN20151990,
BRSSN20159070, BRSSN20159820, BRSSN20169050, BRSSN20176820,
BRSSN20177570, BRSSN20187310, BRSTN20000580, BRSTN20005360,
BRTHA20000570, BRTHA20004740, BRTHA20046290, BRTHA20046390,
BRTHA20046420, CD34C30001250, CD34C30004240, CTONG10000100,
CTONG20004690, CTONG20027090, CTONG20050280, CTONG20076130,
CTONG20077790, CTONG20095290, CTONG20095340, CTONG20099380,
CTONG20106520, CTONG20118250, CTONG20121010, CTONG20127450,
CTONG20128470, CTONG20141650, CTONG20143690, CTONG20153300,
CTONG20155180, CTONG20158150, CTONG20161850, CTONG20164990,
CTONG20186320, D3OST10002700, D6OST20003580, D9OST20000310,
D9OST20035800, DFNES20010910, DFNES20071130, HCHON20002260,
HCHON20003220, HCHON20010990, HCHON20015350, HCHON20022470,
HCHON20067220, HCHON20067700, HEART20003060, HEART20005410,
HEART20061950, HEART20090000, HHDPC10000650, HHDPC20057940,
HLUNG20033780, KIDNE20011170, KIDNE20027250, KIDNE20104300,
KIDNE20107500, KIDNE20122910, KIDNE20127100, KIDNE20180710,
LIVER10001260, LIVER20064100, LIVER20087510, MAMGL10000830,
MESAN20031900, MESAN20036460, MESAN20106640, MESAN20164090,
NOVAR10000150, NOVAR20000380, NT2NE20010400, NT2NE20010490,
NT2NE20021620, NT2NE20122430, NT2NE20125050, NT2NE20174920,
NT2RI20001330, NT2RI20023590, NT2RI20041880, NT2RI20046080,
NT2RI20216250, NT2RI20252550, NT2RP60000770, NT2RP70045590,
NT2RP70063950, NT2RP70195430, NT2RP70198350, NTONG20028070,
NTONG20046140, NTONG20064840, NTONG20067830, NTONG20077560,
PANCR10000910, PEBLM20024550, PEBLM20052820, PEBLM20074370,
PERIC20004780, PLACE50000660, PLACE60079250, PLACE60136720,
PLACE60138830, PROST20005670, PROST20050670, PROST20107820,
PROST20111050, PROST20116600, PROST20120160, PROST20123530,
PROST20161950, PROST20171280, PROST20175290, PROST20185830,
PROST20191640, PUAEN20015860, PUAEN20030180, PUAEN20044000,
PUAEN20078980, PUAEN20085150, PUAEN20108240, SKMUS20012010,
SKNSH20062340, SMINT20013480, SMINT20042990, SMINT20053300,
SMINT20076470, SMINT20092330, SMINT20101440, SMINT20121220,
SMINT20121950, SMINT20122910, SMINT20130320, SMINT20131810,
SMINT20144800, SMINT20163960, SPLEN20002220, SPLEN20008740,
SPLEN20011410, SPLEN20016260, SPLEN20027440, SPLEN20029310,
SPLEN20033960, SPLEN20054290, SPLEN20126190, SPLEN20128000,
SPLEN20145720, SPLEN20146450, SPLEN20147110, SPLEN20149110,
SPLEN20157880, SPLEN20158900, SPLEN20171210, SPLEN20179180,
SPLEN20186430, SPLEN20204170, SPLEN20212730, SPLEN20214580,
SPLEN20250390, STOMA20051200, STOMA20062290, STOMA20092890,
SYNOV20003970, TESOP20005270, TESTI10000940, TESTI20001720,
TESTI20002720, TESTI20004890, TESTI20011200, TESTI20035960,
TESTI20037560, TESTI20044310, TESTI20061110, TESTI20063830,
TESTI20086210, TESTI20152460, TESTI20168960, TESTI20170350,
TESTI20208400, TESTI20213580, TESTI20214250, TESTI20254220,
TESTI20258460, TESTI20330310, TESTI20334410, TESTI20366910,
TESTI20391770, TESTI20432750, TESTI20455620, THYMU20000570,
THYMU20058070, THYMU20066100, THYMU20075320, THYMU20081490,
THYMU20100410, THYMU20101920, THYMU20108310, THYMU20119390,
THYMU20126900, THYMU20128260, THYMU20169680, THYMU20193640,
THYMU20209590, THYMU20235760, THYMU20239430, THYMU20240710,
THYMU20253250, THYMU20286290, TKIDN10000010, TKIDN20005210,
TKIDN20030590, TRACH20005020, TRACH20005400, TRACH20007020,
TRACH20019960, TRACH20034840, TRACH20079690, TRACH20128110,
TRACH20149970, TRACH20183170, UMVEN10001860, UMVEN20003540,
UTERU20000740, UTERU20030570, UTERU20054460, UTERU20055930,
UTERU20056010, UTERU20064860, UTERU20065930, UTERU20070040,
UTERU20081300, UTERU20084260, UTERU20094350, UTERU20120310,
UTERU20124070, UTERU20164260, UTERU20168220, UTERU20183640,
ASTRO20032120, ASTRO20125520, BRACE20039040, BRACE20060720,
BRACE20062640, BRACE20090440, BRACE20099570, BRACE20111830,
BRACE20142570, BRAWH20128270, BRCAN20280360, BRHIP20110800,
BRHIP20176420, BRSSN20003120, CTONG20105660, CTONG20124010,
CTONG20133480, CTONG20139070, CTONG20160560, FCBBF10001210,
FCBBF10001550, FCBBF10001710, FCBBF10001820, FCBBF10002430,
FCBBF10002700, FCBBF10002800, FCBBF10003220, FCBBF10003740,
FCBBF10003760, FCBBF10005060, FCBBF10005460, FCBBF10005500,
FCBBF20006780, FCBBF20014270, FCBBF20023700, FCBBF20032970,
FCBBF20035280, FCBBF20042170, FCBBF20042560, FCBBF20051220,
FCBBF20054280, FCBBF20056370, FCBBF20064520, FCBBF20067810,
FCBBF20071860, FCBBF20072650, FCBBF20076330, FCBBF30008470,
FCBBF30010810, FCBBF30012350, FCBBF30012810, FCBBF30015940,
FCBBF30019120, FCBBF30024750, FCBBF30028180, FCBBF30033050,
FCBBF30039020, FCBBF30052180, FCBBF30054440, FCBBF30057290,
FCBBF30062880, FCBBF30070770, FCBBF30071520, FCBBF30078290,
FCBBF30083620, FCBBF30123470, FCBBF30170590, FCBBF30172550,
FCBBF30175310, FCBBF30178730, FCBBF30190850, FCBBF30195640,
FCBBF30199610, FCBBF30215060, FCBBF30225660, FCBBF30240960,
FCBBF30242250, FCBBF30243640, FCBBF30247930, FCBBF30252520,
FCBBF30252800, FCBBF30252850, FCBBF30262510, FCBBF30266780,
FCBBF30266920, FCBBF30278630, FCBBF30279030, FCBBF30281880,
FCBBF30284720, FCBBF30285280, FCBBF40001730, FCBBF40005480,
HCHON20007380, HEART20072310, HHDPC20068620, HLUNG20023340,
KIDNE20017130, KIDNE20028830, MESAN20014500, NT2RP70072690,
NT2RP70137640, NTONG20067090, PLACE60004630, PROST20083600,
PROST20189770, RECTM20003490, SKNSH20008190, SMINT20115880,
SPLEN20169720, SPLEN20194050, SPLEN20284240, TESTI20083940,
TESTI20213150, TESTI20254540, TESTI20265250, TRACH20118940,
UTERU20145480, UTERU20146680, ASTRO20155290, BRAWH20030250,
BRAWH20113430, BRAWH20122770, BRHIP20005340, BRHIP30001110,
BRSTN20002200, CTONG20052900, CTONG20108210, DFNES20031920,
FEBRA10001900, FEBRA20003210, FEBRA20007620, FEBRA20009090,
FEBRA20010120, FEBRA20017050, FEBRA20018280, FEBRA20025270,
FEBRA20025520, FEBRA20026110, FEBRA20026280, FEBRA20029860,
FEBRA20034680, FEBRA20037260, FEBRA20040530, FEBRA20042190,
FEBRA20052910, FEBRA20060610, FEBRA20072120, FEBRA20079310,
FEBRA20082010, FEBRA20088360, FEBRA20090290, FEBRA20092890,
FEBRA20093520, FEBRA20097310, FEBRA20113560, FEBRA20125070,
FEBRA20132740, FEBRA20140100, FEBRA20161120, FEBRA20166540,
FEBRA20167390, FEBRA20171380, FEBRA20176800, FEBRA20184330,
FEBRA20192420, FEBRA20195820, FEBRA20196370, FEBRA20196630,
FEBRA20197110, FEBRA20211710, FEBRA20214970, FEBRA20215500,
FEBRA20216360, FEBRA20222040, FEBRA20223220, FEBRA20225040,
FEBRA20226010, FEBRA20229560, FEBRA20229630, FEBRA20232850,
FEBRA20235500, HCHON20040020, KIDNE20102650, NT2RP70037240,
PEBLM20072960, PLACE60169420, SKMUS20003610, SMINT20026890,
SMINT20033400, SPLEN20020070, SPLEN20079510, TESTI20001000,
TESTI20094020, THYMU20027560, THYMU20180280, THYMU20271250,
TRACH20003590, UMVEN10001560, UTERU20022940, UTERU20046640,
UTERU20119060, UTERU20144640, UTERU20176130, ASTRO20008010,
BRACE20276430, BRAMY20103570, BRAMY20120910, BRAMY20162510,
BRAMY20196000, BRAWH20164460, BRCAN20273640, BRCOC20105100,
BRHIP20198190, BRHIP20222280, BRHIP20254480, BRHIP30004570,
CTONG20028410, CTONG20091080, CTONG20103480, CTONG20126070,
CTONG20139340, DFNES20001530, HCHON20008150, HHDPC20001040,
HLUNG20016330, HLUNG20017120, IMR3220002430, KIDNE20007210,
KIDNE20021910, KIDNE20124400, MESAN10001260, MESAN20029400,
MESAN20121130, MESAN20153910, NT2NE20159740, NT2NE20177520,
NT2RI20086220, NT2RI20250750, NT2RP60000850, NT2RP70044280,
NT2RP70056750, NT2RP70081610, NTONG20009770, OCBBF10000540,
OCBBF10001750, OCBBF20006770, OCBBF20013890, OCBBF20019830,
OCBBF20020150, OCBBF20020830, OCBBF20023570, OCBBF20028050,
OCBBF20028650, OCBBF20029800, OCBBF20030280, OCBBF20030910,
OCBBF20035930, OCBBF20037440, OCBBF20041680, OCBBF20045330,
OCBBF20046120, OCBBF20046470, OCBBF20046690, OCBBF20048660,
OCBBF20050770, OCBBF20051610, OCBBF20053430, OCBBF20053490,
OCBBF20053730, OCBBF20054200, OCBBF20054760, OCBBF20060300,
OCBBF20062140, OCBBF20062410, OCBBF20066390, OCBBF20071210,
OCBBF20071840, OCBBF20072240, OCBBF20073540, OCBBF20074140,
OCBBF20076220, OCBBF20079310, OCBBF20079460, OCBBF20081380,
OCBBF20082830, OCBBF20085200, OCBBF20086400, OCBBF20086910,
OCBBF20088140, OCBBF20088220, OCBBF20091150, OCBBF20100400,
OCBBF20103130, OCBBF20104040, OCBBF20105570, OCBBF20107090,
OCBBF20107920, OCBBF20108580, OCBBF20108630, OCBBF20109310,
OCBBF20111770, OCBBF20116850, OCBBF20118970, OCBBF20120390,
OCBBF20121390, OCBBF20122620, OCBBF20124360, OCBBF20127040,
OCBBF20127140, OCBBF20127550, OCBBF20128120, OCBBF20129360,
OCBBF20130910, OCBBF20132850, OCBBF20140890, OCBBF20145760,
OCBBF20148280, OCBBF20151150, OCBBF20153340, OCBBF20153350,
OCBBF20155060, OCBBF20164670, OCBBF20170690, OCBBF20173060,
OCBBF20173250, OCBBF20178150, OCBBF20180840, OCBBF20186870,
OCBBF20189560, PEBLM20044520, PEBLM20071880, PLACE60060420,
PROST20047390, PUAEN20003740, SMINT20029760, SPLEN20008820,
SPLEN20084600, SPLEN20095550, SPLEN20099700, SPLEN20140800,
SPLEN20173510, SPLEN20211220, SPLEN20250170, STOMA20067800,
TESTI20031270, TESTI20116830, TESTI20121550, TESTI20234140,
TESTI20442760, THYMU20039810, THYMU20070360, TRACH20033230,
TRACH20084720, BRACE20067430, BRAWH10000930, BRHIP20003120,
BRSSN20152380, FEBRA20024100, FEBRA20027810, FEBRA20037500,
FEBRA20082100, FEBRA20098460, FEBRA20144170, FEBRA20145780,
FEBRA20233770, HHDPC10000830, MESAN20025190, MESAN20089360,
NT2RI20048840, NT2RP70043480, OCBBF20032460, OCBBF20039250,
OCBBF20049300, OCBBF20061720, OCBBF20078920, OCBBF20084660,
OCBBF20087010, PROST20087700, PROST20153320, TRACH20135520,
ADIPS20004250, ASTRO10001650, BRACE20056810, BRACE20059370,
BRACE20106690, BRACE20210140, BRAWH20103290, BRAWH20121640,
BRHIP20005530, BRHIP20217620, BRHIP20218580, BRHIP20238880,
CTONG20075860, CTONG20129960, FCBBF10000240, FCBBF10000630,
FCBBF10001150, FCBBF10004120, FCBBF10005740, FCBBF20075560,
FCBBF30018550, FCBBF30025560, FCBBF30086440, FCBBF30090690,
FCBBF30189490, FCBBF30233680, FCBBF30240020, HCHON20007510,
HCHON20016650, HHDPC20095280, KIDNE20002520, KIDNE20009470,
NT2RI20003480, NT2RI20055790, NT2RP70027380, NT2RP70032610,
NT2RP70062230, OCBBF10001850, OCBBF20022900, OCBBF20026630,
OCBBF20049840, OCBBF20059560, OCBBF20068490, OCBBF20071960,
OCBBF20080410, OCBBF20094240, OCBBF20097720, OCBBF20108190,
OCBBF20108430, OCBBF20126780, OCBBF20130110, OCBBF20139260,
OCBBF20148730, OCBBF20149280, OCBBF20164050, OCBBF20173980,
OCBBF20178880, OCBBF20180120, OCBBF20188730, PROST20057930,
SPLEN20162680, SPLEN20211940, TESTI20184620, TESTI20211240,
TESTI20369690, THYMU20141670, TRACH20028030, UTERU20099720,
UTERU20135860, BRACE20057190, BRHIP20191860, BRHIP20214950,
FCBBF10003670, FCBBF10004370, FCBBF30013770, FCBBF30095260,
FCBBF30246230, FEBRA20002100, FEBRA20034360, FEBRA20095140,
FEBRA20130190, FEBRA20204060, HCHON20008320, LIVER20028420,
TRACH20111130, ASTRO20108190, BRACE20003070, BRACE20060550,
BRAWH20004600, BRAWH20011710, BRAWH20016620, BRHIP10001740,
BRSTN10000830, CTONG10000940, CTONG20150910, D30ST10002670,
FCBBF10000380, FCBBF10000770, FCBBF10003770, FCBBF20059090,
FCBBF30016320, FCBBF30016570, FCBBF30049550, FCBBF30083820,
FCBBF30238870, FCBBF40001420, FEBRA10001880, FEBRA20004620,
FEBRA20080810, FEBRA20086620, FEBRA20095880, HHDPC20034390,
HLUNG10000550, NT2RI20023160, NT2RI20023910, NT2RI20025400,
NT2RI20028470, NT2RI20054050, NT2RI20076290, NT2RI20091730,
NT2RI20091940, NT2RP70036880, NT2RP70078420, OCBBF20047570,
OCBBF20080050, OCBBF20125530, OCBBF20140640, TRACH20032720,
TRACH20141240, UTERU20004240
[0537] The result of comparative analysis of cDNA libraries derived
from fetal heart (FEHRT) and adult heart (HEART) showed that the
genes whose expression levels were different between the two were
the following clones (Table 49).
[0538] FEHRT20003250, OCBBF20189560, BRAWH20029630, CTONG20150910,
HCHON20007510, HEART20003060, HEART20005410, HEART20021840,
HEART20025980, HEART20034320, HEART20037810, HEART20049400,
HEART20049410, HEART20049800, HEART20061950, HEART20063340,
HEART20067870, HEART20067890, HEART20072310, HEART20074430,
HEART20077670, HEART20089940, HEART20090000, HEART20095990,
HLUNG10000550, HLUNG20017120, KIDNE20028390, KIDNE20028830,
NTONG20029480, OCBBF10001750, PROST20127800, SKMUS20001980,
SKMUS20003610, SMINT20026890, SMINT20121220, SMINT20122910,
SMINT20183530, SPLEN20008740, SPLEN20027440, SPLEN20162680,
STOMA20062290, TESTI20254220, THYMU20271250, TRACH20141240,
UTERU20004240
[0539] The result of comparative analysis of cDNA libraries derived
from fetal kidney (FEKID) and adult kidney (KIDNE) showed that the
genes whose expression levels were different between the two were
the following clones (Table 50).
[0540] ASTRO10001650, ASTRO20108190, BGGI120006160, BRACE20039040,
BRACE20060550, BRAMY20102080, BRAWH20004600, BRAWH20125380,
BRAWH20162690, BRHIP20115760, BRHIP20205090, BRHIP20238880,
CTONG20052650, CTONG20108210, CTONG20128470, CTONG20133480,
CTONG20139070, D90ST20000310, DFNES20001530, FCBBF10001820,
FEBRA20002100, HCHON20008980, HCHON20016650, HLUNG20033780,
KIDNE20002520, KIDNE20003940, KIDNE20006780, KIDNE20007210,
KIDNE20007770, KIDNE20008010, KIDNE20009470, KIDNE20011170,
KIDNE20011400, KIDNE20013730, KIDNE20017130, KIDNE20018730,
KIDNE20018970, KIDNE20020150, KIDNE20021680, KIDNE20021910,
KIDNE20021980, KIDNE20022620, KIDNE20024830, KIDNE20027250,
KIDNE20027950, KIDNE20028390, KIDNE20028830, KIDNE20029800,
KIDNE20067330, KIDNE20079440, KIDNE20096280, KIDNE20096470,
KIDNE20100070, KIDNE20100840, KIDNE20101370, KIDNE20101510,
KIDNE20102650, KIDNE20102710, KIDNE20104300, KIDNE20106740,
KIDNE20107390, KIDNE20107500, KIDNE20107620, KIDNE20109730,
KIDNE20109890, KIDNE20112000, KIDNE20115080, KIDNE20118580,
KIDNE20120090, KIDNE20121880, KIDNE20122910, KIDNE20124400,
KIDNE20125630, KIDNE20126010, KIDNE20126130, KIDNE20127100,
KIDNE20127450, KIDNE20127750, KIDNE20130450, KIDNE20131580,
KIDNE20132180, KIDNE20137340, KIDNE20138010, KIDNE20141190,
KIDNE20144890, KIDNE20148900, KIDNE20163880, KIDNE20180710,
KIDNE20181660, KIDNE20182690, KIDNE20186780, KIDNE20190740,
LIVER20035110, MESAN20025190, NOVAR20000380, NT2RI20054050,
NT2RP70043480, PROST20107820, PROST20123530, PROST20161950,
PUAEN20030180, SKMUS20003610, SMINT20033400, TBAES20000590,
TESTI20044310, TESTI20082330, TRACH20032720, UTERU20099720,
BRACE20003070, BRCOC20031870, CTONG20125640, FCBBF30016320,
HCHON20002260, HLUNG10000550, PROST20130530, SPLEN20169720,
SPLEN20194050, KIDNE20028720
[0541] The result of comparative analysis of cDNA libraries derived
from fetal lung (FELNG) and adult lung (HLUNG) showed that the
genes whose expression levels were different between the two were
the following clones (Table 51).
[0542] BRACE20096200, BRAWH20004600, BRAWH20030250, BRCAN20006390,
BRCAN20280360, BRHIP20238880, CTONG10000940, CTONG20103480,
CTONG20129960, CTONG20155180, FCBBF10001210, FEBRA20144170,
FEBRA20197110, HHDPC20034390, HLUNG20016330, HLUNG20016770,
HLUNG20017120, HLUNG20023340, HLUNG20033780, HLUNG20084390,
IMR3220002430, LIVER20028420, NOVAR20000380, NT2RI20054050,
NT2RI20091730, NT2RP70044280, OCBBF20020830, OCBBF20125530,
PLACE60004630, PROST20057930, PROST20107820, PROST20185830,
PUAEN20030180, SMINT20121220, SPLEN20002220, SPLEN20054290,
SPLEN20128000, SPLEN20157300, SPLEN20176200, SPLEN20179180,
SPLEN20211940, STOMA20013890, TBAES20000590, TESTI20094230,
TESTI20184620, TESTI20334410, THYMU20000570, THYMU20039810,
TRACH20007020, TRACH20141240, TRACH20183170, D90ST20033970,
FELNG20002410, HCHON20016650, KIDNE20029800, OCBBF20145760,
SPLEN20162680, TESTI20214250, TRACH20005400, HCHON20002260,
HLUNG10000550, NT2RI20023910, SPLEN20008740
[0543] These genes are involved in regeneration of tissues and/or
cells.
EXAMPLE 8
Expression Frequency Analysis by PCR
[0544] Specific PCR primers were prepared based on the full-length
nucleotide sequences, and the expression frequency was analyzed by
the ATAC-PCR method (Adaptor-tagged competitive PCR method: Nucleic
Acids Research 1997, 25(22): 4694-4696; "DNA Micro-array and
Advanced PCR Techniques", Cell Technology, supplement, Eds.,
Muramatsu and Nawa (Shujunsha, 2000): 104-112).
Inflammation-related genes can be identified by revealing the genes
whose expression levels are altered depending on the presence of an
inflammation-inducing factor. Then, by using THP-1 cell line, which
is a cell line of monocyte line, and TNF-.alpha., which is
inflammation-inducing factor, suitable for this system, the genes
whose expression levels are altered depending on the presence of
the factors were searched for by the system.
[0545] THP-1 cell line (purchased from DAINIPPON PHARMACEUTICAL)
was cultured to be confluent in RPMI1640 medium (sigma) containing
5% fetal calf serum (GIBCO BRL). Then, the medium was changed with
the medium containing 10 ng/ml TNF-.alpha. (human recombinant
TNF-.alpha.; Pharmacia Biotech), and the culture was continued at
37.degree. C. under 5% CO.sub.2. After three hours, the cells were
harvested, and total RNA was extracted from them by using ISOGEN
reagent (Nippon Gene). The extraction was carried out according to
the method in the document attached to ISOGEN reagent. In addition,
total RNA was also extracted from the cells cultured without
stimulation of TNF-.alpha..
[0546] The genes involved in the onset of gastritis and
gastroduodenal ulcer induced by the infection of Helicobacter
pylori to the epithelia of stomach can be identified by revealing
the genes whose expression levels are altered depending on
co-culturing the cells with Helicobacter pylori. A recent study has
suggested that various substances derived from Helicobacter pylori
trigger the inflammation reaction. In particular, the members
belonging to the family of genes called "cag pathogenicity island
(cag PAI)" contribute to the activation of the NF-KB pathway
(Gastroenterology 2000, 119: 97-108). Further, it has been found
that cag PAI is involved in the onset of gastritis and the like by
the study using an animal model (Journal of Experimental Medicine
2000, 192:1601-1610). Then, by using co-culture of a gastric cancer
cell line with cag PAI-positive Helicobacter pylori (TN2), suitable
for this system, the genes whose expression levels are altered
depending on the presence of Helicobacter pylori were searched for
by the system. Further, in order to study the involvement of cag
PAI in the alterations of gene expression levels depending on the
co-culture with Helicobacter pylori, the altered expression levels
were compared between the cells co-cultured with a strain of
Helicobacter pylori (TN2.DELTA.cagE strain) having a mutation in
cagE, which is one of the cag PAI genes, and the cag PAI-positive
strain (TN2).
[0547] A gastric cancer cell line MKN45 (provided by the Cell Bank,
RIKEN GENE BANK, The Institute of Physical and Chemical Research)
was cultured to be confluent in RPMI1640 medium (sigma) containing
10% fetal calf serum (GIBCO BRL). Then, the medium was changed with
the medium containing 100-fold excess (in terms of the number of
cells or the number of colonies) of Helicobacter pylori (cag PAI
positive strain (TN2) and cagE mutant (TN2.DELTA.cagE): both were
provided by Prof. Omata, Faculty of Medicine, The University of
Tokyo), as compared with the number of the cancer cells. The
culture was continued at 37.degree. C. under 5% CO.sub.2. After
three hours, the cells were harvested, and total RNA was extracted
from them by using ISOGEN reagent (Nippon Gene). The extraction was
carried out according to the method in the document attached to
ISOGEN reagent. In addition, total RNA was also extracted from the
cells cultured without Helicobacter pylori.
[0548] The analysis by the ATAC-PCR method was carried out
basically according to "DNA Micro-array and Advanced PCR
Techniques", Cell Technology, supplement (Genome Science Series 1,
Eds., Muramatsu and Nawa (Shujunsha, 2000): 104-112). Adapter
ligation to the internal standard sample (sample to make the
calibration curve for the clone of interest) and test sample was
carried out in the two separate reaction systems indicated below.
The combination of 6 types of adapters (AD-1, AD-2, AD-3, AD-4,
AD-5 and AD-6: see the sequences indicated below) and the samples
are as follows.
Reaction System A
AD1; internal standard, 10-fold
AD2; THP-1 cells, unstimulated
AD3; internal standard, 3-fold
AD4; THP-1 cells, TNF-.alpha. stimulation for one hour
AD5; THP-1 cells, TNF-.alpha. stimulation for three hours
AD6; internal standard, 1-fold
Reaction system B
AD1; internal standard, 1-fold
AD2; MKN45 cells, unstimulated
AD3; internal standard, 3-fold
AD4; MKN45 cells, co-cultured with TN2(Helicobacter pylori)
AD5; internal standard, 10-fold
AD6; MKN45 cells, co-cultured with TN2AcagE(cagE gene mutant)
[0549] Adapter Sequences: TABLE-US-00003 SEQ ID NO: 4887//
5'-GTACATATTGTCGTTAGAACGCG-3' SEQ ID NO: 4888//
3'-CATGTATAACAGCAATCTTGCGCCTAG-5' AD2; SEQ ID NO: 4889//
5'-GTACATATTGTCGTTAGAACGCGACT-3' SEQ ID NO: 4890//
3'-CATGTATAACAGCAATCTTGCGCTGACTAG-5' AD3; SEQ ID NO: 4891//
5'-GTACATATTGTCGTTAGAACGCGCATACT-3' SEQ ID NO: 4892//
3'-CATGTATAACAGCAATCTTGCGCGTATGACTAG-5' AD4; SEQ ID NO: 4893//
5'-GTACATATTGTCGTTAGAACGCGATCCATACT-3' SEQ ID NO: 4894//
3'-CATGTATAACAGCAATCTTGCGCTAGGTATGACTAG-5' AD5; SEQ ID NO: 4895//
5'-GTACATATTGTCGTTAGAACGCGTCAATCCATACT-3' SEQ ID NO: 4896//
3'-CATGTATAACAGCAATCTTGCGCAGTTAGGTATGACTAG-5' AD6; SEQ ID NO:
4897// 5'-GTACATATTGTCGTTAGAACGCGTACTCAATCCATACT-3' SEQ ID NO:
4898// 3'-CATGTATAACAGCAATCTTGCGCATGAGTTAGGTATGACTAG-5'
[0550] The internal standard sample used for this assay was a
mixture of total RNAs from tissues (or culture cells; all from
UNITECH) of Fetal Brain, Testis, Trachea, and Spleen. RNA was
prepared according to the standard method.
[0551] The sequences of primers specific to the genes and the names
of clones of interest in the analysis are as follows. The gene
specific primers were designed to produce the PCR products of 70 to
200 bp, which are derived from the adapter-containing cDNA. The
sequence of adapter-specific primer (labeled with fluorescence
(FAM)) used in the competitive PCR was GTACATATTGTCGTTAGAACGC (22
nucleotides; SEQ ID NO: 4899). PCR was basically carried out with a
cycling profile of preheating at 94.degree. C. for 3 minutes, and
35 or 40 cycles of denaturation at 94.degree. C. for 30
seconds/annealing at 50.degree. C. for 60 seconds/extension at
72.degree. C. for 90 seconds.
[0552] The nucleotide sequences of clone specific primers used in
the experiments
[0553] Clone name, primer sequence and SEQ ID NO are indicated
below in this order. Each is demarcated by a double slash mark
(//). For a clone for which a primer used in Reaction system A
(THP-1 cells) was different from a primer used in Reaction system B
(MKN45 cells), the sequence of each of the primers was shown.
TABLE-US-00004 3NB6920014080// SEQ ID NO: 4900 GTCCTGAAGGTAGATGCT//
ADRGL20013010// SEQ ID NO: 4901 GGAGGATAGAGCTTGGAG//
ADRGL20067670// SEQ ID NO: 4902 ATAAAACAGGACCAAGGA//
ADRGL20083310// SEQ ID NO: 4903 AAATAAGGCTAAAATGGAACT//
ASTRO20032120// SEQ ID NO: 4904 AGTGCTCCCAATTATCCG//
ASTRO20084250// SEQ ID NO: 4905 TAGAAAATATGCTGGGTG//
ASTRO20152140// SEQ ID NO: 4906 TCATTCTTCTCCCACAGC//
ASTRO20166810// SEQ ID NO: 4907 AGTTTTATTTCCAGGCTATC//
ASTRO20181690// SEQ ID NO: 4908 ATGGAGAACAGGACAGCT//
BLADE20004630// SEQ ID NO: 4909 CAAACATCAACCAGAGAA//
BRACE20006400// SEQ ID NO: 4910 TCCCAATCAGCTAAGGTC//
BRACE20019540// SEQ ID NO: 4911 CAGGTTATCGAGAGTTACAT//
BRACE20038480// SEQ ID NO: 4912 TCTGGTTGGATTTTGTGC//
BRACE20039040// SEQ ID NO: 4913 TGAACTTTGTGGTCTGGT//
BRACE20039440// SEQ ID NO: 4914 TGAACAGTGACATTTTAGG//
BRACE20052160// SEQ ID NO: 4915 AAGAATAAAAGGGACGAG//
BRACE20053630// SEQ ID NO: 4916 GTTTGATACAGATGATTAGGTTA//
BRACE20057620// SEQ ID NO: 4917 GGACAGGTAAGAACTAGGC//
BRACE20058810// SEQ ID NO: 4918 ATCATCTTTCCAATCCAG//
BRACE20060720// SEQ ID NO: 4919 GTACCACCTGACCTTCTG//
BRACE20060840// SEQ ID NO: 4920 AGAAGTTTTATCCCACATTT//
BRACE20061740// SEQ ID NO: 4921 (Reaction system A)//
TAACATAACCCTCCCGTC// //(Reaction system B)// SEQ ID NO: 4922
ATAGTGGTGACGTTCCCC// BRACE20062640// SEQ ID NO: 4923
TCTGTTGCTGAAGGAAAA// BRACE20063780// SEQ ID NO: 4924
TCCTGTGTGCTATTTGAA// BRACE20067430// SEQ ID NO: 4925
AATAACAGCAACTCCAGA// BRACE20090440// SEQ ID NO: 4926
CCCAACATTACCAAAAGT// BRACE20101700// SEQ ID NO: 4927
CAACATTTTCAAGCACTG// BRACE20114780// SEQ ID NO: 4928
GATGTTGGGGTTTGGAAG// BRACE20151320// SEQ ID NO: 4929
ACCAGCTGCCCATAGAAG// BRACE20152870// SEQ ID NO: 4930
GAAGGCAAGATGGTAAGT// BRACE20163150// SEQ ID NO: 4931
CATAGAGAAAGCGGGGAA// BRACE20165830// SEQ ID NO: 4932 (Reaction
system A)// TCTCCCTGTTCTCTCTTT// //(Reaction system B)// SEQ ID NO:
4933 TATGACCCAAACGCCTAG// BRACE20201570// SEQ ID NO: 4934
CCTTCTCATCTAGCTTGC// BRACE20210140// SEQ ID NO: 4935
TACTGATTGGGAAGCACT// BRACE20223330// SEQ ID NO: 4936
GTTGAAATGCTTGAGCAC// BRACE20224500// SEQ ID NO: 4937
ATTTAGAGCGCCATCCTT// BRACE20229280// SEQ ID NO: 4938
CTGAGGGTAAAGGAAGGG// BRACE20235400// SEQ ID NO: 4939
TTTTACGATTGCCTTTGC// BRACE20266750// SEQ ID NO: 4940
TTAGGAGTGAAGACAGGA// BRACE20267250// SEQ ID NO: 4941
GTGCAGTGATAAGTGGCT// BRACE20269710// SEQ ID NO: 4942
AGGCAGGGAAAGTAGGGT// BRALZ20018340// SEQ ID NO: 4943
AGGAGAGGCTTGAGGACT// BRALZ20058880// SEQ ID NO: 4944
AAGGGACCAAAATGAGAG// BRALZ20059500// SEQ ID NO: 4945
AACAGCCCTCTAATGAAA// BRALZ20064740// SEQ ID NO: 4946
ACTCATGTTGCTCCACCT// BRALZ20069760// SEQ ID NO: 4947
TATGTATGGCTTTGAGCA// BRALZ20075450// SEQ ID NO: 4948
GCTGAAGAAATGTGCTGC// BRALZ20088690// SEQ ID NO: 4949
ATCATAGTTGTACATACTTTGGC// BRAMY20002770// SEQ ID NO: 4950
TTCTTTCCTGTAATAGTTGG// BRAMY20004110// SEQ ID NO: 4951
AGCTATCTGTGAAAGTCCT// BRAMY20060920// SEQ ID NO: 4952 (Reaction
system A)// TGCTGTCTCGTGATAAAG// //(Reaction system B)// SEQ ID NO:
4953 TTTCTAATGGTTTGGCAC// BRAM20103570// SEQ ID NO: 4954 (Reaction
system A)// TCAACAGTGCTTTTCCTT// //(Reaction system B)// SEQ ID NO:
4955 GACTCTTCTCCAGGGTGC// BRAMY20144620// SEQ ID NO: 4956
CACGCCATTCTGTTAAAA// BRAMY20152110// SEQ ID NO: 4957
AATGGGCTAAATATTGCT// BRAMY20162510// SEQ ID NO: 4958
GCAAATACAGGTAAATGACAG// BRAMY20163250// SEQ ID NO: 4959
CAAGAGAAATTAAAGAAGACC// BRAMY20163270// SEQ ID NO: 4960 (Reaction
system A)// TGCTTTCAACTGTCATTT// //(Reaction system B)// SEQ ID NO:
4961 GAATGATGCCCGATGTAG// BRAMY20168920// SEQ ID NO: 4962
GAATATCCCTGTGGAGTC// BRAMY20178640// SEQ ID NO: 4963
AGTCTCACTCTATTGCCA// BRAMY20184670// SEQ ID NO: 4964
AACGAATAGCAGGGTAGC// BRAMY20204450// SEQ ID NO: 4965
GGTGACTTACTGGCTGCA// BRAMY20210400// SEQ ID NO: 4966
AAGATTAACCATACAACAGAAA// BRAMY20215230// SEQ ID NO: 4967
TGAACAAGAAACACCAGT// BRAMY20218670// SEQ ID NO: 4968
AGGAGGCACGGTAACAAT// BRAMY20229800// SEQ ID NO: 4969
GTCTTCTGTCTCATGGGG// BRAMY20229840// SEQ ID NO: 4970
AAAGTTCATGAGGGGCTG// BRAMY20231720// SEQ ID NO: 4971
CAGCACAAAATCAGTTAAA// BRAMY20247280// SEQ ID NO: 4972
GGTTTAGATTTATGAGACAAGA// BRAMY20261680// SEQ ID NO: 4973
GTTACTGCAGGGCTTCAG// BRAMY20266850// SEQ ID NO: 4974
TGCATGGAATTAAGGAGT// BRAMY20267130// SEQ ID NO: 4975
AATCTGTAAAATGGGAATAAG// BRAMY20277140// SEQ ID NO: 4976 (Reaction
system A)// ATGAGATTGTGTTGTCCA// //(Reaction system B)// SEQ ID NO:
4977 TTCCAGCATTTTCGTTTT// BRAMY20280720// SEQ ID NO: 4978 (Reaction
system A)// TTCCCAAGTCCAGATTTT// //(Reaction system B)// SEQ ID NO:
4979
CTGAGGAGCAGTGACAAG// BRAWH10000930// SEQ ID NO: 4980
GGGAGAGAAGAGTCCTGC// BRAWH20015350// SEQ ID NO: 4981
GCTATGAAGACAACCAAACT// BRAWH20017010// SEQ ID NO: 4982
AGGAAGACATGGGTCAGC// BRAWH20029630// SEQ ID NO: 4983
GGAGTATCACCATGTAAAGA// BRAWH20100690// SEQ ID NO: 4984 (Reaction
system A)// AAATGAGCACTCCATTCC// //(Reaction system B)// SEQ ID NO:
4985 AATGAGCACTCCATTCCC// BRAWH20106180// SEQ ID NO: 4986 (Reaction
system A)// CATTTTATTGTCACCCAC// //(Reaction system B)// SEQ ID NO:
4987 CCTTTAACAGCATCTCTAGTG// BRAWH20107540// SEQ ID NO: 4988
GTTGAGCTATTTGCAGAG// BRAWH20110660// SEQ ID NO: 4989
CTTAGCAACTTTCCACAC// BRAWH20118230// SEQ ID NO: 4990
GTCAGAAAACTCACACCA// BRAWH20122770// SEQ ID NO: 4991
AAGTTGATAGGGAAGGTTT// BRAWH20126190// SEQ ID NO: 4992
ACCATGTGCTCAGAATCA// BRAWH20132190// SEQ ID NO: 4993
TAAGATTCACACGGTGGA// BRAWH20138660// SEQ ID NO: 4994
GATGGAAAATGTAAGGCT// BRAWH20139410// SEQ ID NO: 4995
CCATCCTCTACACAGCAG// BRAWH20155950// SEQ ID NO: 4996 (Reaction
system A)// CTCTCATTTTGGCTCTGC// //(Reaction system B)// SEQ ID NO:
4997 CTACTCCACCTCTGCTGC// BRAWH20158530// SEQ ID NO: 4998
AGTTTTCTGATGGCCTTG// BRCAN20060190// SEQ ID NO: 4999
AGGTAGCCCCAGAGTCAC// BRCAN20147880// SEQ ID NO: 5000
ACTCAGCAATCAGGTCCA// BRCAN20273340// SEQ ID NO: 5001
AATTATGAGATAGGATGTTAGCT// BRCAN20273640// SEQ ID NO: 5002
CTGCACCGATTTTATAGC// BRCAN20275130// SEQ ID NO: 5003
CACTATCCAGACACACCT// BRCAN20280210// SEQ ID NO: 5004
CACTGGATTTTCTTCACTT// BRCAN20280400// SEQ ID NO: 5005
GGAAGGATAGCAGTTGAT// BRCOC20021550// SEQ ID NO: 5006
TCCAAGCAGAGTTTTCAC// BRCOC20037400// SEQ ID NO: 5007
CAAGTCTGTTCATCTGGT// BRCOC20105100// SEQ ID NO: 5008 (Reaction
system A)// ACTTGAGGTTTCTTGGCA// //(Reaction system B)// SEQ ID NO:
5009 GATTCTTCCCCGACTCAG// BRHIP10001740// SEQ ID NO: 5010
GTACACACCTGCTCCCAC// BRHIP20001630// SEQ ID NO: 5011
GGTCAGTAAGTGGTTGTG// BRHIP20096170// SEQ ID NO: 5012
TTATTTTGGATGCCCCTG// BRHIP20103090// SEQ ID NO: 5013
ACTCCAACAACCTTCATT// BRHIP20105710// SEQ ID NO: 5014
TTTCAAGTATCCTCCCCA// BRHIP20110800// SEQ ID NO: 5015
TAGAACTGCCTCCAACCC// BRHIP20111200// SEQ ID NO: 5016
TACTGAACGGTGACTGGC// BRHIP20118910// SEQ ID NO: 5017
ACAGGAAGGGGAAAGAGT// BRHIP20129720// SEQ ID NO: 5018
GAGGAGAGTGAGAAGGGG// BRHIP20143860// SEQ ID NO: 5019
AGGTCAGGAGAACAAGCC// BRHIP20173150// SEQ ID NO: 5020
CTTTTGCAGAGTTTTCCT// BRHIP20175420// SEQ ID NO: 5021
TCTCTAGGGCAAAACATT// BRHIP20186120// SEQ ID NO 5022 (Reaction
system A)// AATTGATACGCAGGGGAG// //(Reaction system B)// SEQ ID NO:
5023 AAGGTCAGTTGAAGTGCT// BRHIP20194940// SEQ ID NO: 5024
TAGAGAAGGTGAGGCCAG// BRHIP20196410// SEQ ID NO: 5025
GGCATAGAAGTAATCAGAGA// BRHIP20207430// SEQ ID NO: 5026
AAGCTGAACCCCAATAAA// BRHIP20218580// SEQ ID NO: 5027
GATTACCAGAACACAGCC// BRHIP20233090// SEQ ID NO: 5028
GTCCATTTACCAACCGCT// BRHIP20284800// SEQ ID NO: 5029
CACATCTTTACATTTATTGCTATT// BRHIP30004880// SEQ ID NO: 5030
TCTTCTCGTAGGGCTTGA// BRSSN20046570// SEQ ID NO: 5031
AAACACGAAATGGATGAA// BRSSN20142940// SEQ ID NO: 5032
AGAATCAGAGAAGCCGGT// BRSSN20152380// SEQ ID NO: 5033
ATACCCATTTCAGTTCCT// BRSSN20176820// SEQ ID NO: 5034
CAGTCCCAATACAGCTCA// BRSSN20187310// SEQ ID NO: 5035 (Reaction
system A)// CAATGACTAGTTTGTGCA// //(Reaction system B)// SEQ ID NO:
5036 AAAGAAGCCAGGAAGATT// BRTHA20046390// SEQ ID NO: 5037
ACATGGAGCCTGGTTTAG// CD34C30004240// SEQ ID NO: 5038
TGGAAGATACGGATAACTC// CD34C30004940// SEQ ID NO: 5039 (Reaction
system A)// ACCACTGTTCTCTGGTGC// //(Reaction system B)// SEQ ID NO:
5040 CCACCACTGTTCTCTGGT// COLON20043180// SEQ ID NO: 5041
TCGGATTGGGTTAAGGTC// CTONG10000620// SEQ ID NO: 5042
CTCCATTCATCAGACCAC// CTONG20014280// SEQ ID NO: 5043
TCCAAAAGACAGAACAGC// CTONG20095270// SEQ ID NO: 5044
GTTTTGTTCCCTGCTCAC// CTONG20095290// SEQ ID NO: 5045
AACACAGCTCAACAACTC// CTONG20096750// SEQ ID NO: 5046
TGACTAAGCATGGAGACT// CTONG20100240// SEQ ID NO: 5047
AGTCATAATCATCTTCCTCA// CTONG20103480// SEQ ID NO: 5048
GGTGGAGTAATGTATATAACGTAA// CTONG20105660// SEQ ID NO: 5049
CCATTAACACAAACCAAA// CTONG20121010// SEQ ID NO: 5050
GGAAGATGGGACCTCAGT// CTONG20128470// SEQ ID NO: 5051
TTGGGGTATCTTGGAGCT// CTONG20138030// SEQ ID NO: 5052
GGCATAGAAGTAATCAGAGA// CTONG20139070// SEQ ID NO: 5053
TCAAACCTCCTATCTTCTG// CTONG20146970// SEQ ID NO: 5054
TTTTAATCCTCAGTACATTTTC// CTONG20158150// SEQ ID NO: 5055
AAATAGGTTGATGTTGGC// CTONG20186320// SEQ ID NO: 5056
TGACTTTGGCCCTTTACC// CTONG20265130// SEQ ID NO: 5057
GGGTAGGTGCTAGAAATC// D3OST20006540// SEQ ID NO: 5058
GGAGACCACACATAACAT// D3OST20037970// SEQ ID NO: 5059
CACTGACGAAAGGGAAGA// D9OST20031370// SEQ ID NO: 5060
CGACTTGCCAGACTCACT//
DFNES10001850// SEQ ID NO: 5061 GTGGCTCAAAGTAGGATT//
DFNES20031920// SEQ ID NO: 5062 CTTACTCCAACCCAGGCT//
FCBBF10005060// SEQ ID NO: 5063 TGCATGTTTTCTTCCTCA//
FCBBF20032970// SEQ ID NO: 5064 CCAGACACAACAATACCA//
FCBBF20035280// SEQ ID NO: 5065 (Reaction system A)//
ATACAATTTGTGCCTGTTA// //(Reaction system B)// SEQ ID NO: 5066
CGGTAAGTAGTCTTCATGTG// FCBBF20054280// SEQ ID NO: 5067
GGTGCATCTGTACTTGAA// FCBBF20071860// SEQ ID NO: 5068
TGGAGGAGTAGTTATCAGTTG// FCBBF30001840// SEQ ID NO: 5069
AGTGCTCCCAATTATCCG// FCBBF30016320// SEQ ID NO: 5070
GGCTACTCAAGGACACAG// FCBBF30016570// SEQ ID NO: 5071
AGGGATAAGATGGCAGGT// FCBBF30033050// SEQ ID NO: 5072
TCCTGTACTCCTTTCCAT// FCBBF30071520// SEQ ID NO: 5073
CAGGCATAAGAGGTGGCT// FCBBF30083820// SEQ ID NO: 5074
CCTGTGTGATACCAAATACT// FCBBF30215060// SEQ ID NO: 5075
CAGCCCCAATTACTAGAA// FCBBF30251420// SEQ ID NO: 5076
AGCATGTACTGGGAAAGC// FCBBF30252520// SEQ ID NO: 5077
AGGGATAAAGAATGCAAA// FCBBF30262360// SEQ ID NO: 5078
GAGCTTCAGGGGCATTTA// FCBBF30266920// SEQ ID NO: 5079
ATACGCAATTTTCAGACC// FCBBF30278630// SEQ ID NO: 5080
AAAAGACAACGATGCCTG// FCBBF30285280// SEQ ID NO: 5081
AAAGCAAAGTGATATAGGAGT// FCBBF40001420// SEQ ID NO: 5082
ACATTTCAGTCCATTCAC// FEBRA10001880// SEQ ID NO: 5083
TTGTCATGGTGGTAATCC// FEBRA20010120// SEQ ID NO: 5084
GGACCAGACTCACAAATT// FEBRA20017050// SEQ ID NO: 5085
TATACTAAAACCCAGCCA// FEBRA20034360// SEQ ID NO: 5086
CGGCAGCTAGAAAACCTC// FEBRA20037260// SEQ ID NO: 5087
CGTTGGTTTTCTGGACAC// FEBRA20037500// SEQ ID NO: 5088
CTCGGGCAGGATTAACTC// FEBRA20082100// SEQ ID NO: 5089
AGAAGATGCTAGGTTTGC// FEBRA20095880// SEQ ID NO: 5090
AGCATGTACTGGGAAAGC// FEBRA20167390// SEQ ID NO: 5091
GCTTATGTTGCAGTTTCA// FEBRA20176800// SEQ ID NO: 5092
TCAGTTTCAGGGGTCAAG// FEBRA20226010// SEQ ID NO: 5093
TCAGGGTATCAGCTTTCC// HCASM10000500// SEQ ID NO: 5094
TGTGGTGACTTACTGCCT// HCHON20002260// SEQ ID NO: 5095
CTCTCCAACAAACTGCAC// HCHON20008980// SEQ ID NO: 5096
CTGCTGCCTTACACAACC// HCHON20009350// SEQ ID NO: 5097
AGGTAATGAGGAATGCAC// HCHON20010990// SEQ ID NO: 5098
GATTCCACCCTCAAGATT// HCHON20011160// SEQ ID NO: 5099
CTCCTCCACGCTTGTTTT// HCHON20015230// SEQ ID NO: 5100
CTTGGTCACAGTTTTCAT// HCHON20022470// SEQ ID NO: 5101
CACACTTTCAATCCGAGG// HCHON20035130// SEQ ID NO: 5102
GTGGAAGATGCTCGACTG// HCHON20043590// SEQ ID NO: 5103
AGGATTAGGTATTGCTTCTC// HCHON20067220// SEQ ID NO: 5104
TAAGGAAAACCCAACCAC// HCHON20076500// SEQ ID NO: 5105
GAAAGACACCTGGCACAC// HEART20021840// SEQ ID NO: 5106
GTACCCCAAAAGAAACAT// HEART20067870// SEQ ID NO: 5107
GAACTATCTAATCACATGGG// HEART20083640// SEQ ID NO: 5108 (Reaction
system A)// TCTTGATGTCTCCTGCCT// //(Reaction system B)// SEQ ID NO:
5109 CTCGGCTGGAAGGTAAAA// HHDPC10000650// SEQ ID NO: 5110
ACTGGTAAGATATGGGCA// HHDPC20034390// SEQ ID NO: 5111
CTCTCCCAAACTCAGGTC// HHDPC20095280// SEQ ID NO: 5112
TGACCCAAAGACATACTG// HLUNG10000550// SEQ ID NO: 5113
GATTTACTTCCGGTTTCG// KIDNE20018970// SEQ ID NO: 5114
AAGAGAATAAGGCTGGGC// KIDNE20028720// SEQ ID NO: 5115
AACAAAATAAGGGGCCAG// KIDNE20079440// SEQ ID NO: 5116
AAGTTCATCTGGGTGTGG// KIDNE20096470// SEQ ID NO: 5117
ATCACCTGGAGAGCTTTG// KIDNE20106740// SEQ ID NO: 5118
AGGGACACTGAGAACTGG// KIDNE20120090// SEQ ID NO: 5119
GAAGCAGGGAAGTGTGAG// KIDNE20127750// SEQ ID NO: 5120
GCTATTACACATTCTGCATT// KIDNE20130450// SEQ ID NO: 5121
CAGCTACTTGGGACAGGA// KIDNE20132180// SEQ ID NO: 5122 (Reaction
system A)// ACCAGCTCAGCAAGAACT// //(Reaction system B)// SEQ ID NO:
5123 CTCTGACATGAACTGGTG// KIDNE20141190// SEQ ID NO: 5124
CACATTGCCTAGAGAAAG// KIDNE20148900// SEQ ID NO: 5125
ACAACAGCAGATGACTCG// KIDNE20163880// SEQ ID NO: 5126
CAGTCACATCTCCCTTTA// KIDNE20182690// SEQ ID NO: 5127
TCACTGTATCACCATCTG// LIVER10004790// SEQ ID NO: 5128
TCCCTGCTAAGATGTTGA// LIVER20011130// SEQ ID NO: 5129
GAGGTCAAGGACACACAG// LIVER20038540// SEQ ID NO: 5130 (Reaction
system A)// AAGCAATGTGGCAGACTC// //(Reaction system B)// SEQ ID NO:
5131 AGTGGGTTCTTTATCATTTT// LIVER20055440// SEQ ID NO: 5132
GTTTGCCAGGGAATGTTT// LIVER20062510// SEQ ID NO: 5133
GTAACGTGCTCTGAATGA// LIVER20085800// SEQ ID NO: 5134
GCTCTGCTGTTTCTAATTT// MAMGL10000830// SEQ ID NO: 5135
TCGATACGTGGAAGAATT// MESAN20031900// SEQ ID NO: 5136
TCCCAAGGCTGTAGTTCA// MESAN20121130// SEQ ID NO: 5137
AGCTTGTATCTAAATTCGTG// MESAN20127350// SEQ ID NO: 5138
CAGAAGACAGGTTGCCAG// MESAN20130220// SEQ ID NO: 5139
CCTAAGATTGGTCGTCCT// MESAN20154010// SEQ ID NO: 5140
ATCCTGTCATCTTTTCGC// MESAN20174170// SEQ ID NO: 5141
TGGCTAAGGTTCTCAGGA// NOVAR10001020// SEQ ID NO: 5142
GGGTCAGTAAATCTAATGC//
NT2NE20053580// SEQ ID NO: 5143 CAAAACACAGAGTTATCAGAA//
NT2NE20089610// SEQ ID NO: 5144 TGCTGTCCTAGAAGAATAAA//
NT2NE20089970// SEQ ID NO: 5145 ACAATTATACTGGAAAAGCA//
NT2NE20146810// SEQ ID NO: 5146 GCTGAGACCTTTTGCTAG//
NT2NE20155110// SEQ ID NO: 5147 AGCCGAGGTTTTGAGTTA//
NT2NE20156260// SEQ ID NO: 5148 ACATTTGCACTGGAACTG//
NT2NE20158600// SEQ ID NO: 5149 CTCAGAAGCCCAGCAATT//
NT2NE20172590// SEQ ID NO: 5150 ACATCATAATCAAGCAGTAAA//
NT2NE20174920// SEQ ID NO: 5151 AGGACAGCAACAAGAGAG//
NT2NE20181650// SEQ ID NO: 5152 AGAGCTGATTTATACGCA//
NT2RI20005750// SEQ ID NO: 5153 AAGGAGTCTACGAAGCAC//
NT2RI20009870// SEQ ID NO: 5154 AAGATGACCCCGAGTTTG//
NT2RI20023160// SEQ ID NO: 5155 CATGCAAATAGAGGACTG//
NT2RI20040930// SEQ ID NO: 5156 CCATACTGTTCTCTGCTG//
NT2RI20046080// SEQ ID NO: 5157 CCGTAACTTTTATATGCCTG//
NT2RI20055790// SEQ ID NO: 5158 GCAAGAGCTACAGACAAA//
NT2RI20069730// SEQ ID NO: 5159 AGTGTGCAGAAATCCGTG//
NT2RI20203900// SEQ ID NO: 5160 AGCAGTAGCACAGCCTTA//
NT2RP70062230// SEQ ID NO: 5161 (Reaction system A)//
ACTCTAACACATTTGGCA// //(Reaction system B)// SEQ ID NO: 5162
TATTAGTGTCAGCTGGCA// NT2RP70102350// SEQ ID NO: 5163 (Reaction
system A)// ATAGGAGGTGTCATGCCC// //(Reaction system B)// SEQ ID NO:
5164 TCTTTTGACCTACACTGC// NT2RP70110860// SEQ ID NO: 5165
GGGGAAGGGAGTAAGGTC// NT2RP70111320// SEQ ID NO: 5166
ACTTAGCATCCAGACCTC// NT2RP70130020// SEQ ID NO: 5167
ATACTCTCTGCTCATGGA// NT2RP70143480// SEQ ID NO: 5168
TTCTTGGCATCCTTCATT// NT2RP70150800// SEQ ID NO: 5169 (Reaction
system A)// GAGGCTTGTCTAGGGGAA// //(Reaction system B)// SEQ ID NO:
5170 GAACAAGGGATGCAGGAT// NT2RP70157890// SEQ ID NO: 5171 (Reaction
system A)// TATGTGATGTTTTCCCCA// //(Reaction system B)// SEQ ID NO:
5172 CTGCCTAAATAACACTGAAG// NT2RP70169110// SEQ ID NO: 5173
CTGTCCTCATCTGTGCAT// NT2RP70175670// SEQ ID NO: 5174
GGTAGAACGGGAAATCAT// NT2RP70188020// SEQ ID NO: 5175
AGGTTTGAGTAGAGGGAA// NT2RP70188710// SEQ ID NO: 5176
ATACAGCAGGGAAGAGGC// NT2RP70190640// SEQ ID NO: 5177
CAATGTGTCTTCAGTTTCC// NTONG20029480// SEQ ID NO: 5178
TCTTGATGTCTCCTGCCT// NTONG20064840// SEQ ID NO: 5179
AAAGCCATCGTACACCAT// NTONG20067090// SEQ ID NO: 5180
AATTCTTTAGCTCTGTTGC// NTONG20070340// SEQ ID NO: 5181
ATCCACTGCCCCTTATCA// NTONG20077560// SEQ ID NO: 5182
CTGCTAGAATACGCCTTA// NTONG20083650// SEQ ID NO: 5183
CTCATAGTTCAAGGCAGC// NTONG20090680// SEQ ID NO: 5184
GAGTAAGGTCGTAGTCAGTG// OCBBF20005230// SEQ ID NO: 5185
GCAAGACCTACAGACAAA// OCBBF20019380// SEQ ID NO: 5186
GTGGTCAGTGGAAAATGG// OCBBF20020150// SEQ ID NO: 5187
GGGACAGTATGGCAGAGA// OCBBF20020830// SEQ ID NO: 5188
GCTTGCCATAGGTGTACT// OCBBF20039250// SEQ ID NO: 5189
TTTCAGCAGTTAAGTGTTTT// OCBBF20041680// SEQ ID NO: 5190
TCAGAAGGTATGCCCACT// OCBBF20047570// SEQ ID NO: 5191
ACCCTTATGTCAAACTGC// OCBBF20051610// SEQ ID NO: 5192
TTTTCCTACCTGCAATGG// OCBBF20054200// SEQ ID NO: 5193
GTCACAAGCCATACGTGC// OCBBF20061720// SEQ ID NO: 5194
CAAAGTGGCCTAAACCCT// OCBBF20062140// SEQ ID NO: 5195
CTGGGGAGATAAGAGCCT// OCBBF20071960// SEQ ID NO: 5196 (Reaction
system A)// CTCAGTCACGCAATAGAT// //(Reaction system B)// SEQ ID NO:
5197 TCTCTGGAAGGGAAAATT// OCBBF20072320// SEQ ID NO: 5198
AAGAAGGAATGGGCACAC// OCBBF20079310// SEQ ID NO: 5199
CAGTAGCAAAACCAGAGC// OCBBF20081380// SEQ ID NO: 5200
GTGGAAGTGCCTGATGAG// OCBBF20085200// SEQ ID NO: 5201
TACAGGGTCAGTTGGCAG// OCBBF20094240// SEQ ID NO: 5202
ACACAATTCATCACTGCT// OCBBF20107920// SEQ ID NO: 5203
GGTTGCTGTGAGTGCATT// OCBBF20127040// SEQ ID NO: 5204
TAGAGGAGGCAGTAAGGG// OCBBF20130110// SEQ ID NO: 5205
AGTGTCTATGGCTCTTCC// OCBBF20139260// SEQ ID NO: 5206
GGGTGGTTCTGTTAGGAG// OCBBF20164050// SEQ ID NO: 5207
TGCTGGAAATAATCGCTT// OCBBF20178990// SEQ ID NO: 5208
TGAGTGTGGTGAAGATAGT// OCBBF20180840// SEQ ID NO: 5209
AGAAACCTGAACGATGTC// PEBLM10000240// SEQ ID NO: 5210
ATTACGATGCTTTGTTCA// PEBLM20013120// SEQ ID NO: 5211
TAAAATTCTTGTGGTTGG// PEBLM20024550// SEQ ID NO: 5212
TTGTGCCCTTAGAAAATC// PEBLM20052820// SEQ ID NO: 5213
CCTGATAACCATGAATTG// PEBLM20074370// SEQ ID NO: 5214
AGCATTTGGTTTTATACTGTTA// PERIC20002140// SEQ ID NO: 5215
CGTTACCATCACAATTTCA// PERIC20004780// SEQ ID NO: 5216
ACTTGAGCAGAGGAGAGC// PLACE60003480// SEQ ID NO: 5217
ACTGGTATTTGCTGTGAA// PLACE60136720// SEQ ID NO: 5218
AGGAACAGAGGCTACATC// PLACE60155130// SEQ ID NO: 5219
GTCTAGCTGGGATGATGG// PLACE60169420// SEQ ID NO: 5220
AAGACCCCGATAGAGAGC// PLACE60181070// SEQ ID NO: 5221
CCTTCTTCAGTCTTGCAC// PROST10004800// SEQ ID NO: 5222
AGTTTTGTTCACCCCTCC// PROST20120160// SEQ ID NO: 5223
TAGAATGGTGGGAAGTGG// PROST20144220// SEQ ID NO: 5224
TTAGTGGTCTGTTGATAGTTTT//
PROST20149160// SEQ ID NO: 5225 TTGGCCTTAGGTGAGTCC//
PROST20149250// SEQ ID NO: 5226 GGTACATAAGGAATCGCT//
PROST20151240// SEQ ID NO: 5227 (Reaction system A)//
ACTCTCGCTTCCTGTCAC// //(Reaction system B)// SEQ ID NO: 5228
GACGGACCCTTGACATTA// PROST20153320// SEQ ID NO: 5229
ACTGTGGAGAAGGAGGGA// PROST20161950// SEQ ID NO: 5230
ATTTGACGTATCCATGCC// PROST20189770// SEQ ID NO: 5231
TGGTAAGTGGTGGAAGCT// PUAEN20003740// SEQ ID NO: 5232
CCAAAACAATAATCCAACAT// PUAEN20011880// SEQ ID NO: 5233
AGCCGTTGTCATCATAGA// PUAEN20015260// SEQ ID NO: 5234
ATTGGAAGTCCCTATGAT// PUAEN20025680// SEQ ID NO: 5235
CTCCTCTGAAGTAGCTGC// PUAEN20040670// SEQ ID NO: 5236
AATGGTTCTCTGGCTTGG// PUAEN20045250// SEQ ID NO: 5237
CAAAATGGTTAAACACAAA// PUAEN20078980// SEQ ID NO: 5238
AGAAAGGCACACAATAAA// PUAEN20085150// SEQ ID NO: 5239
AATTTAGGGGAACTGAGTAC// SKMUS20018230// SEQ ID NO: 5240
TTCGCTCTTATCACCCAG// SKMUS20028210// SEQ ID NO: 5241
ACTTCCCTTGGAATTGCT// SKMUS20031680// SEQ ID NO: 5242
CAGAAGAACAGGAGGCAC// SKMUS20046670// SEQ ID NO: 5243
GCAACGTCTTACTGTGAA// SKNSH20062340// SEQ ID NO: 5244
GACATTGACGTATTCTAACTG// SKNSH20080430// SEQ ID NO: 5245
TACCCTCCGCTGTGTTAG// SMINT20001760// SEQ ID NO: 5246
CTCCTCCAGCTCTTGTCC// SMINT20013480// SEQ ID NO: 5247
GGCACGTTTTAATATACCAC// SMINT20014580// SEQ ID NO: 5248
CCCTCCAGACAGTTCAAA// SMINT20033400// SEQ ID NO: 5249
CGATGGGTAGGACTTAAA// SMINT20047810// SEQ ID NO: 5250 (Reaction
system A)// CTCCTGACATTTCCTTTT// //(Reaction system B)// SEQ ID NO:
5251 TAGGAAAAGAAGCAGGGC// SMINT20051610// SEQ ID NO: 5252
AGTGAGGTTAGGGAAATATC// SMINT20056210// SEQ ID NO: 5253
TATTCCTGTTTGATGGGG// SMINT20060780// SEQ ID NO: 5254
TCTGTAATAGGGAGGTGTC// SMINT20080540// SEQ ID NO: 5255
GAGGTACTTTTCAGACAGG// SMINT20105000// SEQ ID NO: 5256 (Reaction
system A)// AAAATGAGGTTCAGTCCC// //(Reaction system B)// SEQ ID NO:
5257 TCACCTCCCCATTAACTG// SMINT20108530// SEQ ID NO: 5258
CACCCTCGTTTTCTTTAG// SMINT20122850// SEQ ID NO: 5259
AGCTAAATCCACTGAGGT// SMINT20122910// SEQ ID NO: 5260
GGACAGACTTGCAGAGAA// SMINT20153530// SEQ ID NO: 5261
GGGCCTAGAGTGGAAGTG// SMINT20161220// SEQ ID NO: 5262
AGAACCAGTCCAAGCCAT// SMINT20163960// SEQ ID NO: 5263
TTGATAAAATAGAGCCCA// SMINT20164770// SEQ ID NO: 5264
AGTGTGCAGAAATCCGTG// SMINT20168570// SEQ ID NO: 5265 (Reaction
system A)// TGGTCCTCATGGTACAGC// //(Reaction system B)// SEQ ID NO:
5266 ATGGCTGCTAGCTTGTCA// SPLEN20008820// SEQ ID NO: 5267
CTGTCTGCCCTGAATCTT// SPLEN20011410// SEQ ID NO: 5268
TTTTGGGACTGGAAGGAG// SPLEN20013540// SEQ ID NO: 5269
TCACTCACACCAATCCTG// SPLEN20019450// SEQ ID NO: 5270
TTCGTAAACATCTGGGCA// SPLEN20022230// SEQ ID NO: 5271
AAGTTGCACCCAGACATC// SPLEN20040600// SEQ ID NO: 5272
TCTTATTTCACAGTTTCCA// SPLEN20076530// SEQ ID NO: 5273
CCCCACAGAACACTTACT// SPLEN20111190// SEQ ID NO: 5274
AGACGTAGCAGCAACTCC// SPLEN20126190// SEQ ID NO: 5275
TAGACCCAACCCTCACAC// SPLEN20152760// SEQ ID NO: 5276
TGAGACGAATTGGTAAAA// SPLEN20157300// SEQ ID NO: 5277
CTTGACATTTGCTCTCCA// SPLEN20158990// SEQ ID NO: 5278
AAAACTGGGTCAAATAAAA// SPLEN20163560// SEQ ID NO: 5279
TGCCCAGATAGAAAAGTG// SPLEN20174260// SEQ ID NO: 5280
GGCCTTGTTGAATCTGAA// SPLEN20211570// SEQ ID NO: 5281
CTCAACACAACTCCAAGC// SPLEN20214580// SEQ ID NO: 5282
CCAAACGAATGTCAAGCT// SPLEN20245300// SEQ ID NO: 5283
ATCTGCTCTTCATCCCTT// SPLEN20279950// SEQ ID NO: 5284
CCTGTTCCTACACCGCAT// SPLEN20280660// SEQ ID NO: 5285
GGCCAGACAGGAAGAGTT// SPLEN20283650// SEQ ID NO: 5286
AAGTTGATGCTCCTGTTG// SPLEN20329240// SEQ ID NO: 5287 (Reaction
system A)// TAACACATGGACTGCTGG// //(Reaction system B)// SEQ ID NO:
5288 AAGGTAGGAAATGCCAGC// STOMA20010250// SEQ ID NO: 5289
TTTTGACCATAAGCTCCT// STOMA20032890// SEQ ID NO: 5290
CGAGAAATAACTAATACACCTG// STOMA20048520// SEQ ID NO: 5291
GAGGGTGAAGCAGGTAGG// STOMA20057820// SEQ ID NO: 5292
GGCATTTCCCTTGTATATT// STOMA20062290// SEQ ID NO: 5293
CCGTGTATTCAGCTCCCT// STOMA20076800// SEQ ID NO: 5294
TAAACGGGAATCAGGAAG// TESTI20001170// SEQ ID NO: 5295
TTTCAGACATATCAAGTTCA// TESTI20002780// SEQ ID NO: 5296
ATTCCAGCCATACGGTTA// TESTI20004890// SEQ ID NO: 5297
AAAACCACAGGAAGAAAG// TESTI20011200// SEQ ID NO: 5298
TACAAGTTCACCTGCATT// TESTI20018230// SEQ ID NO: 5299
AACCACTCAGCAGAAAGA// TESTI20035960// SEQ ID NO: 5300
TGTCCATAGAGCCAGTTA// TESTI20038270// SEQ ID NO: 5301
GTTCTGTTGGAGGTGCTG// TESTI20044230// SEQ ID NO: 5302
AGGTCTTTTGTGTGCTGA// TESTI20046750// SEQ ID NO: 5303
GTAGTTGTCCTGCATGGC// TESTI20060400// SEQ ID NO: 5304
GGCCAGGATACTACACTT// TESTI20066770// SEQ ID NO: 5305
AACTGGCATTGGAGACCT// TESTI20076850// SEQ ID NO: 5306
TTGGTTTGTGATGTTAAGT//
TESTI20083940// SEQ ID NO: 5307 TTTGTCTTCCGGTAGTTA//
TESTI20087620// SEQ ID NO: 5308 TGCCACTCTTGAAAACTC//
TESTI20098530// SEQ ID NO: 5309 TCCATTACACAACAGCCT//
TESTI20105720// SEQ ID NO: 5310 GGCAGACTTGTTTGAGCT//
TESTI20108720// SEQ ID NO: 5311 TAGTTCTGTTGAGGCCCC//
TESTI20123080// SEQ ID NO: 5312 (Reaction system A)//
CCTGTTTCTCTTCCTGAA// //(Reaction system B)// SEQ ID NO: 5313
CTAAGTCCAGAAGCCTCG// TESTI20128350// SEQ ID NO: 5314
ATACCATGCTCCAACACC// TESTI20136100// SEQ ID NO: 5315
TTCACTTTTGTTCTCCAG// TESTI20137670// SEQ ID NO: 5316
CCTCCACTCTTCCTGTTG// TESTI20143240// SEQ ID NO: 5317
CTAAGAAGTCCTGGTTGG// TESTI20143620// SEQ ID NO: 5318 (Reaction
system A)// TTTTGTCTGAATTTGGAA// //(Reaction system B)// SEQ ID NO:
5319 TGTAGAAAGCCTAACCCC// TESTI20156100// SEQ ID NO: 5320
ACTGGGCACATTCATAAA// TESTI20161970// SEQ ID NO: 5321
GTTCTATGCCTTGAGCCT// TESTI20168480// SEQ ID NO: 5322
AACTCTGGGTACCAACTT// TESTI20168960// SEQ ID NO: 5323
CTCCCTCTCCTTTCCTCA// TESTI20178160// SEQ ID NO: 5324
CGTTTTCTCGATGTCCAG// TESTI20185810// SEQ ID NO: 5325
AACATTCCTTGCAGCTCA// TESTI20199170// SEQ ID NO: 5326
AGAGTGAGCTGTGCCTTG// TESTI20200260// SEQ ID NO: 5327
CCAAGACATACCCAGGCT// TESTI20200710// SEQ ID NO: 5328
AATTGTGACAAGCAGCAG// TESTI20202650// SEQ ID NO: 5329
TGTTCATGTCACTGGCTG// TESTI20220100// SEQ ID NO: 5330 (Reaction
system A)// CTTCATAGGGCAGACTCC// //(Reaction system B)// SEQ ID NO:
5331 GCTGTGAACTAGAGGGGC// TESTI20224620// SEQ ID NO: 5332
GGAGAAACCGATGAAGAA// TESTI20229600// SEQ ID NO: 5333 (Reaction
system A)// TTTAATAGTGCCCTGTGG// //(Reaction system B)// SEQ ID NO:
5334 CTCTGGAATTTGCATTGA// TESTI20230850// SEQ ID NO: 5335
CAAGACTATGGAGGGGAG// TESTI20231920// SEQ ID NO: 5336
CTCCTCTTGCATTCTCCC// TESTI20234140// SEQ ID NO: 5337
CCAGTTATATCCCCAAAA// TESTI20234270// SEQ ID NO: 5338
CATAAAACCGAATAACTGAG// TESTI20238000// SEQ ID NO: 5339
AGTGTTTGTGGGCATAGA// TESTI20238610// SEQ ID NO: 5340
ACTTCAGACCTCCCTAGA// TESTI20239510// SEQ ID NO: 5341
TTATTGAAGGAAAGCCGC// TESTI20242990// SEQ ID NO: 5342
CCCTGCCTTCCCTATAGA// TESTI20265250// SEQ ID NO: 5343
GGGAAATAGAGGAGTGAT// TESTI20265370// SEQ ID NO: 5344
TGGTTTCAGATGTGCCTT// TESTI20266740// SEQ ID NO: 5345
TGGAAGAACGAAAGAGCC// TESTI20272390// SEQ ID NO: 5346
TCCAGGGTGTCGTAGAAG// TESTI20275030// SEQ ID NO: 5347
GCACGTTAAGGACTGTTT// TESTI20275620// SEQ ID NO: 5348 (Reaction
system A)// TGTGCCTGACTAGGTGAG// //(Reaction system B)// SEQ ID NO:
5349 AAGGACAGGTGAGTGTGG// TESTI20277360// SEQ ID NO: 5350
TGGAGTACAACCTGCATC// TESTI20282540// SEQ ID NO: 5351
TGTCTGGTAGAGTTGCGG// TESTI20284880// SEQ ID NO: 5352
TGATTTAATGAGTGGAACC// TESTI20285830// SEQ ID NO: 5353 (Reaction
system A)// CATGTGACCTTCTCTGGC// //(Reaction system B)// SEQ ID NO:
5354 CAGTTCTTTAGCCAGGGA// TESTI20288110// SEQ ID NO: 5355
CCTTTTGTCTGATTCGTC// TESTI20289850// SEQ ID NO: 5356
CCTTACCAAACTCATCCA// TESTI20307540// SEQ ID NO: 5357
CGTGCATGAAAGTGAGTC// TESTI20308600// SEQ ID NO: 5358
CTTCTCAATCATCAGGGA// TESTI20311290// SEQ ID NO: 5359
TTCTCTGCACTCCTTGAT// TESTI20317600// SEQ ID NO: 5360
GAGTGTCTGGCATGGTTA// TESTI20319190// SEQ ID NO: 5361
AAGCTGGGATGATAAGGG// TESTI20332420// SEQ ID NO: 5362 (Reaction
system A)// CTTCTTGGTGCTGCTTTT// //(Reaction system B)// SEQ ID NO:
5363 GCAGATATGTTTGTGAGAG// TESTI20335200// SEQ ID NO: 5364
AATAAACTACACCAGGGC// TESTI20342430// SEQ ID NO: 5365
TCCTACGTTGAGTTGCCT// TESTI20345060// SEQ ID NO: 5366
GTCCACTAGAAGAGGGTC// TESTI20347300// SEQ ID NO: 5367
GAAAGCTGTCGTTAAGGT// TESTI20357960// SEQ ID NO: 5368
AATGACAGGTGAGTGGGT// TESTI20361140// SEQ ID NO: 5369
AATTCACCAGGCTGTGTG// TESTI20369220// SEQ ID NO: 5370 (Reaction
system A)// TGGATTTGGAAGAGACCT// //(Reaction system B) SEQ ID NO:
5371 //TTTGGGTGGAAGTAGAGA// TESTI20369690// SEQ ID NO: 5372
GCTGGTTATTCACGTGGT// TESTI20370020// SEQ ID NO: 5373 (Reaction
system A)// TGGTCATACTCACTGCCC// //(Reaction system B)// SEQ ID NO:
5374 GACCTGGTCATACTCACTG// TESTI20371030// SEQ ID NO: 5375
CTAAAGTCCAAAATGTGTAAGT// TESTI20386230// SEQ ID NO: 5376 (Reaction
system A)// GCTAAGGTGCTATGAAGG// //(Reaction system B)// SEQ ID NO:
5377 ACAGTAAAAGGGCAAGTG// TESTI20391210// SEQ ID NO: 5378
AATACTCACATGCCAAGC// TESTI20392090// SEQ ID NO: 5379
CTTGGTTACAGAGGACAG// TESTI20392250// SEQ ID NO: 5380
ATTCCACTCTGCTCAAAG// TESTI20392270// SEQ ID NO: 5381
CCTTGTTGTCCATGAGTC// TESTI20401020// SEQ ID NO: 5382
CGTACACCACATAGCTGA// TESTI20401430// SEQ ID NO: 5383
TGGTAGAAAGAGAGTCACAT// TESTI20409440// SEQ ID NO: 5384
TAGAGCACGTTTCCCTGA// TESTI20415640// SEQ ID NO: 5385
TCTGGAAAATGAGGGTTA// TESTI20424000// SEQ ID NO: 5386
CCAGCTTTCTTCATCATC// TESTI20424730// SEQ ID NO: 5387
AGGAGTGTGGCATAGTCA// TESTI20425070// SEQ ID NO: 5388
AAAGCCATCAGACCTCAT// TESTI20433130// SEQ ID NO: 5389
GTCCCATGATTTAGAACTC// TESTI20438570// SEQ ID NO: 5390
CTGCACTAGCCTTTTCCA// TESTI20443090// SEQ ID NO: 5391
GGAAGACAGGACCCAAGT// TESTI20463520// SEQ ID NO: 5392
TGTTGGACTAGAGGGGAA// TESTI20465520// SEQ ID NO: 5393
TCCAGGTCTCATTCTCTC// TESTI20478010// SEQ ID NO: 5394
TCCCTATCAGACGACCAG// TESTI20478180// SEQ ID NO: 5395
AAATCACCCTGCTTGTCA// THYMU20029100// SEQ ID NO: 5396
AGAAGCCAGGGAAGAGGT// THYMU20061700// SEQ ID NO: 5397
CTAGCTCTGAAGTGGCAT// THYMU20095960// SEQ ID NO: 5398 (Reaction
system A)// TGAAGAGATTACCCAGGT// //(Reaction system B)// SEQ ID NO:
5399 GGACTCTGTAGATGTAACTGA// THYMU20111180// SEQ ID NO: 5400
(Reaction system A)// TTCTGGGTAAGCCTGATT// //(Reaction system B)//
SEQ ID NO: 5401 CAAAGAATACCACAAATAGC// THYMU20118060// SEQ ID NO:
5402 CCAAGGCTAAAGAGAGAG// THYMU20130890// SEQ ID NO: 5403 (Reaction
system A)// AATCTCAAGGACCAGTTT// //(Reaction system B)// SEQ ID NO:
5404 GACACAATGGACTCAAAA// THYMU20142040// SEQ ID NO: 5405
ACAGAAGGCCACAGTCAG// THYMU20142970// SEQ ID NO: 5406
CAAGGATACTGTGATGAAA// THYMU20153160// SEQ ID NO: 5407
GGTGGTTAGGACATTTCTC// THYMU20158250// SEQ ID NO: 5408
AAGGAGTGGATAGATGAATAG// THYMU20187720// SEQ ID NO: 5409
TGGTTACAAAGTCACAGG// THYMU20194360// SEQ ID NO: 5410
TTCACTTTTGTTTCCCAG// THYMU20208300// SEQ ID NO: 5411
ATACCACTAAGGCCCAGG// THYMU20226600// SEQ ID NO: 5412
GACTCTTTCAGCTGCTGC// THYMU20239000// SEQ ID NO: 5413
CAAATGGACAGGAACTTA// THYMU20253250// SEQ ID NO: 5414 (Reaction
system A)// AGAAAACCAGATAGGGCC// //(Reaction system B)// SEQ ID NO:
5415 TAATGCAGGGAATGGAGT// THYMU20272490// SEQ ID NO: 5416
CATTATACACACGACGAA// THYMU20284120// SEQ ID NO: 5417
AAACCCACAGTGCTTCAT// THYMU20286290// SEQ ID NO: 5418
AGTCCCTCTCATTTCCAG// TKIDN10000010// SEQ ID NO: 5419
TGCCATAATTCTCCTTTT// TRACH20005020// SEQ ID NO: 5420
GCTTTTCTCCTTCCATGA// TRACH20032720// SEQ ID NO: 5421
CTACGCCCACTATATTCA// TRACH20041830// SEQ ID NO: 5422 (Reaction
system A)// AGATACTGAGAATGAGCCT// //(Reaction system B)// SEQ ID
NO: 5423 TTTCCATGCCTACCCTTT// TRACH20060150// SEQ ID NO: 5424
(Reaction system A)// AGTCTCCTGCTGGCTAAG// //(Reaction system B)//
SEQ ID NO: 5425 GTCCCTTCTGTCTCCTGA// TRACH20076760// SEQ ID NO:
5426 GTGGAAGTGCCTGATGAG// TRACH20082780// SEQ ID NO: 5427
CTTTCACCTGGGATGGAT// TRACH20091230// SEQ ID NO: 5428
AACATAGTCATTTCGTTCA// TRACH20099340// SEQ ID NO: 5429
GAGCACTGTAAGAGCCAT// TRACH20109650// SEQ ID NO: 5430
AAACATACCACGGAGAGA// TRACH20115740// SEQ ID NO: 5431
TATGAGCACACGAGGTCC// TRACH20134950// SEQ ID NO: 5432
AAGAGGGAACATCAGGCT// TRACH20135520// SEQ ID NO: 5433
TTCTTGGGCTTTATGTGG// TRACH20153810// SEQ ID NO: 5434 (Reaction
system A)// GCAGTGAGTCGTAGATGA// //(Reaction system B)// SEQ ID NO:
5435 CTGCCTAGCCCTCTCACT// TRACH20184490// SEQ ID NO: 5436
ACTGTGAAGAGCCTGTTG// TSTOM20001390// SEQ ID NO: 5437
GGAATAGTAAGGACATAATGACA// TSTOM20005690// SEQ ID NO: 5438
GGAACCTTTTGTAACCCT// UMVEN10001560// SEQ ID NO: 5439
GCCACAACATCATTTTACTT// UMVEN20003540// SEQ ID NO: 5440
AAGTAAAAGACATCGGCA// UTERU20004240// SEQ ID NO: 5441
TACCTCCAGACTTTTGTG// UTERU20046980// SEQ ID NO: 5442
AGGATGGGAAGAAGGTTT// UTERU20055930// SEQ ID NO: 5443
GGATGAGTTGTGTGAAAA// UTERU20068990// SEQ ID NO: 5444
CCAAGGCTAAAGAGAGAG// UTERU20070810// SEQ ID NO: 5445
AAGTAGAGAATCCCAGCT// UTERU20115740// SEQ ID NO: 5446
TTTATGATTGAGGGGACC// UTERU20119060// SEQ ID NO: 5447
ACAGCATCCAATCAAAGA// UTERU20124070// SEQ ID NO: 5448
ACATCTGGTGGAAGCATC// UTERU20126880// SEQ ID NO: 5449
ACCTTAACCCCTCTTCCC// UTERU20134910// SEQ ID NO: 5450
AAGGAAGCCAACTCATGC// UTERU20146680// SEQ ID NO: 5451
ACCTTAACCCCTCTTCCC// UTERU20176130// SEQ ID NO: 5452
TAGAAAGGGGTGGTGAGA// UTERU20185230// SEQ ID NO: 5453
CGTTGAGAGCTTTTACAG// UTERU20186740// SEQ ID NO: 5454
CCACTTTGAGAGAACCCT//
[0554] The result of expression frequency analysis is shown in
Table 52. The clones not shown in the table contain clones whose
expression levels could not be measured because the levels were too
low or the sizes of the PCR products were different from the
expected. It was confirmed that the expression levels of IL-8 genes
used as positive control genes were elevated.
[0555] The result obtained by the search for the genes whose
expression levels were altered depending on the presence of
TNF-.alpha. in culturing THP-1 cell, which is a human monocyte cell
line, showed that the clones whose expression levels were elevated
by twofold or more one or three hours after the stimulation (the
clones whose expression levels were 0.1 or lower both before and
after the stimulation were excluded), were ASTRO20152140,
[0556] BRACE20057620, BRACE20060720, BRACE20090440, BRACE20152870,
BRACE20229280, BRAMY20002770, BRAMY20266850, BRAMY20280720,
BRAWH20106180, BRAWH20122770, BRHIP20096170, BRHIP20111200,
BRHIP20186120, BRHIP20194940, BRHIP20207430, BRSSN20152380,
CTONG20095270, CTONG20100240, CTONG20158150,
[0557] CTONG20265130, D30ST20006540, D90ST20031370, FCBBF20071860,
FCBBF30251420, FCBBF30252520, FCBBF40001420, FEBRA20017050,
FEBRA20082100, HCHON20011160, KIDNE20141190, KIDNE20163880,
KIDNE20182690, LIVER10004790, LIVER20038540, LIVER20085800,
MESAN20130220, MESAN20174170, NT2NE20158600, NT2RI20005750,
NT2RP70110860, NT2RP70169110, NT2RP70175670, NT2RP70188710,
PERIC20002140, PLACE60155130, PROST20120160, PROST20149250,
PROST20161950, PUAEN20015260, SKNSH20080430, SMINT20051610,
SMINT20060780, SMINT20161220, SMINT20163960, SPLEN20101190,
SPLEN20157300, SPLEN20163560, SPLEN20214580, SPLEN20279950,
STOMA20048520, TESTI20076850, TESTI20087620, TESTI20108720,
TESTI20220100, TESTI20239510, TESTI20266740, TESTI20342430,
TESTI20370020, TESTI20391210, TESTI20401020, TESTI20415640,
THYMU20130890, THYMU20286290, TRACH20060150, TRACH20099340,
UTERU20004240, UTERU20068990, UTERU20119060.
[0558] On the other hand, in particular cases where the expression
levels were relatively high in the unstimulated cells (the relative
value was 1 or higher), the clones whose expression levels were
decreased by twofold or more by the TNF-.alpha. stimulation (the
clones whose expression levels were increased 1 or 3 hours after
the stimulation were excluded) were
[0559] ASTRO20032120, ASTRO20084250, ASTRO20181690, BRACE20062640,
BRACE20067430, BRACE20235400, BRALZ20018340, BRALZ20069760,
BRALZ20075450, BRAMY20163270, BRAMY20204450, BRAMY20218670,
BRAMY20229800, BRAWH10000930, BRAWH20107540, BRAWH20132190,
BRAWH20158530, BRCAN20273340, BRHIP20105710, BRHIP20186120,
BRSSN20176820, CTONG20095290, DFNES20031920, FCBBF30033050,
FCBBF30071520, FCBBF30083820, HCHON20008980, HCHON20022470,
HHDPC20034390, KIDNE20028720, KIDNE20079440, KIDNE20127750,
KIDNE20148900, LIVER20011130, MAMGL10000830, MESAN20127350,
NT2NE20181650, NT2RI20023160, NT2RP70102350, NT2RP70157890,
NTONG20029480, OCBBF20020830, OCBBF20041680, OCBBF20061720,
OCBBF20127040, OCBBF20139260, OCBBF20178990, PEBLM20013120,
PLACE60003480, PLACE60181070, PROST20151240, PUAEN20003740,
PUAEN20011880, PUAEN20078980, PUAEN20085150, SKNSH20080430,
SMINT20001760, SMINT20047810, SMINT20108530, SPLEN20158990,
SPLEN20283650, STOMA20010250, STOMA20057820, TESTI20060400,
TESTI20161970, TESTI20275620, TESTI20369690, TESTI20386230,
TESTI20392250, TESTI20409440, TESTI20424730, THYMU20095960,
THYMU20111180, THYMU20226600, THYMU20253250, THYMU20272490,
TRACH20153810, UTERU20176130, UTERU20186740.
[0560] These clones were thus revealed to be involved in the
inflammation reaction induced by TNF-.alpha..
[0561] The result obtained by the search for the genes whose
expression levels were altered depending on co-culturing gastric
cancer cell line MKN45 with cag PAI positive Helicobacter pylori
(TN2), showed that the clones whose expression levels were elevated
by twofold or more (the clones whose expression levels were 0.1 or
lower both before and after the stimulation were excluded), were
ADRGL20067670, BLADE20004630, BRACE20039040,
[0562] BRACE20151320, BRACE20229280, BRACE20235400, BRALZ20058880,
BRAMY20060920, BRAMY20184670, BRAMY20218670, BRAMY20229800,
BRCAN20147880, BRHIP20196410, BRHIP30004880, BRSSN20187310,
CD34C30004940, CTONG20265130, DFNES20031920, FCBBF30278630,
FCBBF40001420,
[0563] HHDPC20095280, KIDNE20130450, LIVER20011130, LIVER20038540,
NT2NE20172590, NT2RP70169110, OCBBF20085200, OCBBF20180840,
PEBLM10000240, PLACE60003480, PROST20120160, PROST20151240,
PUAEN20011880, SKMUS20031680, SKNSH20080430, SMINT20056210,
SMINT20105000, SPLEN20019450, SPLEN20211570, STOMA20048520,
TESTI20004890, TESTI20083940, TESTI20168480, TESTI20239510,
TESTI20308600, TESTI20478010, UTERU20126880.
[0564] Of these clones, the expression levels of ADRGL20067670,
[0565] BLADE20004630, BRACE20151320, BRACE20229280, BRACE20235400,
BRALZ20058880, BRAMY20218670, BRAMY20229800, BRHIP20196410,
BRHIP30004880, CD34C30004940, DFNES20031920, FCBBF30278630,
FCBBF40001420, HHDPC20095280, KIDNE20130450, LIVER20011130,
LIVER20038540, NT2NE20172590, NT2RP70169110,
[0566] PEBLM10000240, PROST20151240, PUAEN20011880, SKMUS20031680,
SKNSH20080430, SMINT20056210, SMINT20105000, SPLEN20019450,
SPLEN20211570, STOMA20048520, TESTI20168480, TESTI20308600,
TESTI20478010, UTERU20126880 were not increased by the co-culture
with the cagE mutant (TN2.DELTA.cagE). There may be the possibility
that the expression levels of the 34 clones are altered via the
NF-.kappa.B pathway. Among them, the expression levels of
BRACE20229280, FCBBF40001420, LIVER20038540, NT2RP70169110,
SKNSH20080430, STOMA20048520 were also increased when human
monocyte cell line THP-1 was stimulated with TNF-.alpha..
[0567] On the other hand, in particular cases where the expression
levels were relatively high in the unstimulated cells (the relative
value was 1 or higher), the clones whose expression levels were
decreased by twofold or more in the presence of Helicobacter pylori
were ASTRO20032120, BRACE20090440,
[0568] BRACE20114780, BRALZ20064740, BRAMY20002770, BRAMY20210400,
BRAMY20215230, BRAMY20247280, BRAMY20267130, BRAWH20029630,
BRAWH20100690, BRAWH20118230, BRCOC20105100, BRHIP20218580,
BRSSN20046570, CTONG20138030, CTONG20146970, CTONG20158150,
D3OST20037970, FCBBF30001840,
[0569] FCBBF30033050, FEBRA20082100, HCHON20035130, HCHON20043590,
HCHON20067220, NT2NE20174920, NT2RI20009870, NT2RI20023160,
NT2RP70062230, NT2RP70130020, NTONG20070340, OCBBF20020150,
OCBBF20094240, OCBBF20107920, PROST20144220, PROST20149160,
PROST20153320, PUAEN20003740, PUAEN20025680, PUAEN20040670,
SMINT20014580, SPLEN20101190, STOMA20076800, TESTI20087620,
TESTI20098530, TESTI20123080, TESTI20161970, TESTI20234140,
TESTI20288110, TESTI20357960, TESTI20391210, TESTI20424730,
THYMU20158250, THYMU20226600, TRACH20005020, TRACH20134950,
TRACH20184490, TSTOM20001390, UTERU20119060, UTERU20134910,
UTERU20176130.
[0570] These clones are involved in gastritis or gastroduodenal
ulcer. TABLE-US-00005 TABLE 3 CloneID CD34C D3OST D6OST D9OST
ASTRO20001410 0 17.731 0 20.479 D3OST10001090 0 62.515 0 24.068
D3OST20036070 0 46.404 0 53.596 THYMU20039810 0 18.291 0 21.126
KIDNE20028720 0 0 38.385 46.259 BRAWH10000930 0 0 0 6.219
BRHIP20005340 0 0 0 4.615 CTONG20141650 0 0 0 64.925 D9OST20000310
0 0 0 63.705 D9OST20002780 0 0 0 100 D9OST20023970 0 0 0 37.837
D9OST20026730 0 0 0 19.695 D9OST20031370 0 0 0 100 D9OST20033970 0
0 0 38.536 D9OST20035800 0 0 0 93.047 D9OST20035940 0 0 0 100
D9OST20040180 0 0 0 100 FCBBF30018550 0 0 0 37.763 FCBBF30233680 0
0 0 33.084 KIDNE20102650 0 0 0 63.715 NT2RI20023160 0 0 0 10.811
PROST20107820 0 0 0 3.279 SKNSH20089400 0 0 0 25.857 SMINT20033400
0 0 0 39.619 CTONG20108210 0 0 47.973 0 D6OST20003580 0 0 95.4 0
D6OST20005070 0 0 100 0 ASTRO20155290 0 21.631 0 0 D3OST10002670 0
50.415 0 0 D3OST10002700 0 30.165 0 0 D3OST20006180 0 100 0 0
D3OST20006540 0 100 0 0 D3OST20007340 0 93.334 0 0 D3OST20013280 0
100 0 0 D3OST20024170 0 100 0 0 D3OST20024360 0 100 0 0
D3OST20037970 0 100 0 0 D3OST30002580 0 72.574 0 0 D3OST30002910 0
93.334 0 0 FCBBF10004120 0 22.594 0 0 NT2RI20001330 0 29.915 0 0
NTONG20009770 0 11.477 0 0 SPLEN20084600 0 30.589 0 0 SPLEN20140800
0 55.315 0 0 THYMU20169680 0 86.295 0 0 TRACH20141240 0 12.051 0 0
CD34C30001250 97.628 0 0 0 CD34C30003140 100 0 0 0 CD34C30004240
96.167 0 0 0 CD34C30004940 100 0 0 0 DFNES10001850 55.393 0 0 0
HHDPC20034390 21.364 0 0 0 NT2RI20091730 46.845 0 0 0 SKMUS20003610
44.913 0 0 0 SPLEN20225220 59.537 0 0 0 BRCOC20101230 46.01 0 0
14.772
[0571] TABLE-US-00006 TABLE 4 Clone ID NT2RM NT2RP NT2RI NT2NE
CTONG20027090 62.349 0 0 0 CTONG20160560 57.22 0 0 0 NT2RP70032610
39.095 3.274 0 0 OCBBF20188730 39.876 0 0 0 SPLEN20162680 12.432 0
2.355 6.263 BRCOC20101230 0 2.64 3.981 3.97 BRHIP20005340 0 0.825
1.244 1.24 BRHIP20238880 0 2.66 7.355 2.667 FCBBF30016320 0 7.441
2.805 5.595 FEBRA20080810 0 6.827 5.147 2.566 FEBRA20225040 0 3.958
2.985 5.952 HCHON20008320 0 17.053 19.287 12.822 HHDPC20034390 0
0.613 1.387 0.922 HLUNG10000550 0 2.609 0.984 1.962 NT2RI20028470 0
9.076 6.843 4.549 NT2RI20054050 0 2.03 1.02 4.069 NT2RI20091730 0
2.688 2.027 4.042 NT2RP70078420 0 4.623 3.485 13.902 PUAEN20003740
0 2.314 0.582 1.16 THYMU20271250 0 0.431 0.651 1.297 BRACE20003070
0 8.516 4.281 0 BRACE20039040 0 6.248 4.711 0 BRAWH20004600 0 1.471
5.545 0 BRAWH20011710 0 8.931 2.245 0 BRCOC20121720 0 13.559 5.112
0 BRHIP20005530 0 12.387 9.34 0 D3OST10002700 0 6.227 4.695 0
HCHON20007380 0 7.176 5.411 0 HEART20072310 0 11.675 17.605 0
KIDNE20121880 0 21.519 16.225 0 MESAN20121130 0 14.219 10.721 0
NT2RI20022600 0 57.012 42.988 0 NT2RI20023160 0 1.932 1.457 0
NT2RI20086220 0 7.606 5.735 0 NT2RI20216250 0 45.928 34.63 0
NT2RP60000850 0 11.147 16.809 0 NT2RP70036880 0 1.78 5.367 0
NT2RP70043480 0 10.893 4.107 0 NT2RP70062230 0 10.183 7.678 0
NT2RP70081610 0 15.131 22.818 0 NT2RP70102350 0 84.14 15.86 0
NT2RP70130020 0 57.012 42.988 0 NT2RP70190640 0 30.952 23.338 0
OCBBF10001850 0 20.293 7.65 0 OCBBF20097720 0 5.676 4.28 0
OCBBF20173980 0 3.1 2.338 0 PEBLM20044520 0 3.253 2.453 0
SPLEN20173510 0 7.249 10.932 0 TRACH20007020 0 9.462 7.134 0
UTERU20065930 0 10.676 8.05 0 HCHON20022470 0 6.766 0 10.174
NT2NE20010490 0 21.179 0 31.847 NT2NE20174800 0 39.941 0 60.059
NT2NE20177520 0 28.292 0 42.542 PROST20087700 0 1.88 0 14.135
PROST20107820 0 0.586 0 2.644 SMINT20028820 0 6.998 0 10.523
TESTI20063830 0 9.768 0 14.689 ASTRO20125520 0 0 2.686 5.357
BRHIP30001110 0 0 1.86 3.71 HCHON20002260 0 0 0.733 1.461
HCHON20008150 0 0 5.075 20.242 KIDNE20002520 0 0 1.553 6.195
NT2NE20130190 0 0 33.397 66.603 NT2NE20158600 0 0 33.397 66.603
NT2RI20001330 0 0 4.656 9.286 NT2RI20025400 0 0 3.141 6.265
NT2RI20036670 0 0 33.397 66.603 NT2RI20048840 0 0 1.404 5.6
SKMUS20020840 0 0 11.346 22.628 BRACE20057190 0 0 0 10.763
BRACE20060550 0 0 0 14.499 BRACE20267250 0 0 0 66.449 BRAWH20107540
0 0 0 40.54 BRAWH20118230 0 0 0 78.374 CTONG20075860 0 0 0 21.782
CTONG20095290 0 0 0 22.915 FEBRA20086620 0 0 0 11.505 FEBRA20144170
0 0 0 1.957 FEBRA20196370 0 0 0 59.247 HLUNG20023340 0 0 0 33.313
NT2NE20003740 0 0 0 100 NT2NE20010050 0 0 0 84.719 NT2NE20010210 0
0 0 100 NT2NE20010400 0 0 0 56.184 NT2NE20015240 0 0 0 100
NT2NE20021620 0 0 0 44.305 NT2NE20043780 0 0 0 100 NT2NE20053580 0
0 0 75.239 NT2NE20068130 0 0 0 100 NT2NE20072200 0 0 0 100
NT2NE20074250 0 0 0 100 NT2NE20080170 0 0 0 100 NT2NE20089610 0 0 0
100 NT2NE20089970 0 0 0 100 NT2NE20108540 0 0 0 84.719
NT2NE20110360 0 0 0 100 NT2NE20118960 0 0 0 100 NT2NE20122430 0 0 0
76.57 NT2NE20124480 0 0 0 100 NT2NE20125050 0 0 0 66.449
NT2NE20131890 0 0 0 100 NT2NE20132170 0 0 0 100 NT2NE20142210 0 0 0
100 NT2NE20146810 0 0 0 100 NT2NE20152750 0 0 0 100 NT2NE20155110 0
0 0 100 NT2NE20156260 0 0 0 100 NT2NE20157470 0 0 0 100
NT2NE20159740 0 0 0 27.684 NT2NE20172590 0 0 0 100 NT2NE20174920 0
0 0 61.159 NT2NE20181650 0 0 0 100 NT2NE20183760 0 0 0 100
NT2NE20184900 0 0 0 84.719 NT2NE20187390 0 0 0 100 OCBBF20108430 0
0 0 53.98 RECTM20005100 0 0 0 10.923 SMINT20001760 0 0 0 50.667
SPLEN20169720 0 0 0 7.349 TESTI20265250 0 0 0 15.768 ASTRO10001650
0 0 8.055 0 ASTRO20033160 0 0 10.721 0 BRACE20011070 0 0 26.748 0
BRACE20039440 0 0 0.941 0 BRACE20151320 0 0 29.94 0 BRAMY20104640 0
0 40.041 0 BRAMY20137560 0 0 68.63 0 BRAMY20167060 0 0 9.007 0
BRAWH20028110 0 0 15.672 0 BRCAN20280360 0 0 4.387 0 BRCOC20004870
0 0 0.526 0 BRHIP20207990 0 0 9.197 0 BRHIP20217620 0 0 5.063 0
BRHIP20249110 0 0 67.372 0 BRSTN10000830 0 0 3.481 0 CTONG10000940
0 0 1.415 0 CTONG20004690 0 0 5.307 0 CTONG20050280 0 0 12.439 0
CTONG20105660 0 0 24.642 0 CTONG20125640 0 0 7.18 0 CTONG20133520 0
0 49.384 0 CTONG20186320 0 0 29.069 0 FCBBF10000770 0 0 1.472 0
FCBBF10002800 0 0 10.265 0 FCBBF10003770 0 0 19.652 0 FCBBF30018550
0 0 5.089 0 FCBBF30123470 0 0 3.989 0 FCBBF30246230 0 0 5.091 0
FEBRA20018280 0 0 9.887 0 FEBRA20095140 0 0 6.019 0 FEBRA20192420 0
0 58.974 0 HCHON20064590 0 0 19.614 0 HHDPC10000830 0 0 1.779 0
HLUNG20016770 0 0 6.385 0 HLUNG20033780 0 0 16.824 0 IMR3220002430
0 0 3.118 0 KIDNE20104300 0 0 17.33 0 MESAN20004570 0 0 7.197 0
MESAN20089360 0 0 14.459 0 NOVAR10000910 0 0 3.519 0 NT2RI20003480
0 0 32.207 0 NT2RI20005750 0 0 100 0 NT2RI20009870 0 0 100 0
NT2RI20023590 0 0 29.911 0 NT2RI20023910 0 0 11.79 0 NT2RI20025640
0 0 100 0 NT2RI20040930 0 0 100 0 NT2RI20041880 0 0 10.436 0
NT2RI20046080 0 0 6.723 0 NT2RI20050960 0 0 73.545 0 NT2RI20055790
0 0 17.054 0 NT2RI20056700 0 0 100 0 NT2RI20069730 0 0 100 0
NT2RI20076290 0 0 14.653 0 NT2RI20091940 0 0 5.358 0 NT2RI20198260
0 0 100 0 NT2RI20203900 0 0 100 0 NT2RI20207030 0 0 100 0
NT2RI20240080 0 0 61.866 0 NT2RI20244600 0 0 100 0 NT2RI20244960 0
0 100 0 NT2RI20250750 0 0 30.809 0 NT2RI20252550 0 0 62.102 0
NT2RI20273230 0 0 60.375 0 NTONG20067090 0 0 16.469 0 OCBBF10001750
0 0 13.09 0 OCBBF20047570 0 0 4.504 0 OCBBF20054760 0 0 8.495 0
OCBBF20059560 0 0 10.318 0 OCBBF20073540 0 0 3.651 0 OCBBF20125530
0 0 2.131 0 OCBBF20126780 0 0 12.535 0 OCBBF20127040 0 0 37.942 0
OCBBF20140890 0 0 35.863 0 SKMUS20003610 0 0 1.943 0 SKNSH20008190
0 0 4.523 0 SKNSH20080430 0 0 18.4 0 SMINT20144800 0 0 2.887 0
SPLEN20027440 0 0 4.053 0 SPLEN20095550 0 0 15.436 0 SPLEN20140800
0 0 8.61 0 TESTI20094020 0 0 16.66 0 TESTI20369690 0 0 6.529 0
TESTI20391770 0 0 7.531 0 TESTI20442760 0 0 17.235 0 TRACH20084720
0 0 5.703 0 TRACH20107710 0 0 61.866 0 TRACH20118940 0 0 16.16 0
UTERU20022940 0 0 9.896 0 ASTRO20108190 0 1.622 0 0 BGGI120006160 0
2.155 0 0 BRAMY20136210 0 70.518 0 0 BRAWH20016620 0 22.162 0 0
BRAWH20164460 0 20.968 0 0 BRCOC20144000 0 40.488 0 0 BRHIP20132860
0 82.532 0 0 BRSSN20146100 0 17.209 0 0 CTONG10000100 0 15.625 0 0
CTONG20103480 0 4.268 0 0 CTONG20108210 0 1.722 0 0 CTONG20139070 0
10.392 0 0 FCBBF10000240 0 10.583 0 0 FCBBF10000630 0 14.415 0 0
FCBBF20067810 0 30.502 0 0 FCBBF30010810 0 6.328 0 0 FCBBF30012810
0 49.073 0 0 FCBBF30013770 0 24.817 0 0 FCBBF30039020 0 56.608 0 0
FCBBF40001420 0 8.811 0 0 FEBRA10001880 0 5.044 0 0 FEBRA20082010 0
17.339 0 0 HHDPC20001040 0 4.459 0 0 KIDNE20021910 0 34.358 0 0
NT2RP60000770 0 15.492 0 0 NT2RP70010740 0 100 0 0 NT2RP70027380 0
27.748 0 0 NT2RP70037240 0 22.256 0 0 NT2RP70044280 0 16.256 0 0
NT2RP70045590 0 20.543 0 0 NT2RP70056750 0 7.009 0 0 NT2RP70063950
0 82.532 0 0 NT2RP70072690 0 56.608 0 0 NT2RP70077660 0 74.295 0
0
NT2RP70085440 0 100 0 0 NT2RP70105210 0 100 0 0 NT2RP70110860 0 100
0 0 NT2RP70111320 0 100 0 0 NT2RP70122910 0 100 0 0 NT2RP70125160 0
100 0 0 NT2RP70133740 0 100 0 0 NT2RP70134990 0 100 0 0
NT2RP70137290 0 100 0 0 NT2RP70137640 0 54.725 0 0 NT2RP70143480 0
100 0 0 NT2RP70147210 0 100 0 0 NT2RP70150800 0 100 0 0
NT2RP70157890 0 100 0 0 NT2RP70159960 0 100 0 0 NT2RP70169110 0 100
0 0 NT2RP70175670 0 100 0 0 NT2RP70179710 0 100 0 0 NT2RP70181970 0
100 0 0 NT2RP70188020 0 100 0 0 NT2RP70188710 0 100 0 0
NT2RP70192730 0 100 0 0 NT2RP70194450 0 100 0 0 NT2RP70195430 0
50.987 0 0 NT2RP70198350 0 2.512 0 0 NT2RP70203790 0 100 0 0
OCBBF20039250 0 4.016 0 0 OCBBF20080410 0 5.038 0 0 OCBBF20108190 0
30.231 0 0 OCBBF20108580 0 16.054 0 0 OCBBF20122620 0 34.956 0 0
OCBBF20130110 0 18.197 0 0 OCBBF20151150 0 43.004 0 0 OCBBF20189560
0 4.079 0 0 PROST10003220 0 57.613 0 0 TESTI20001720 0 20.618 0 0
TESTI20121550 0 15.444 0 0 TESTI20152460 0 28.533 0 0 TESTI20211240
0 13.774 0 0 TESTI20234140 0 39.241 0 0 UMVEN20003540 0 1.985 0 0
UTERU20006960 0 6.858 0 0 UTERU20094350 0 12.888 0 0 UTERU20164260
0 30.63 0 0
[0572] TABLE-US-00007 TABLE 5 CloneID BEAST TBAES BRACE20039040 0
18.237 BRAMY20163250 0 26.506 BRCOC20031250 0 39.975 BRHIP20005340
0 2.408 BRHIP20217620 0 19.598 BRHIP30001110 0 7.202 FCBBF10000770
0 5.697 FCBBF30010810 0 18.471 FEBRA20080810 0 9.963 FEBRA20144170
0 3.798 FEBRA20196630 0 61.269 FEBRA20197110 0 14.875 HCHON20002260
0 11.347 HCHON20040020 0 5.523 HHDPC20034390 0 1.789 HLUNG10000550
0 3.808 NOVAR10000910 0 27.245 NT2RI20023160 0 11.28 NT2RI20054050
0 1.975 NT2RI20091730 0 7.846 OCBBF20188730 0 9.748 SMINT20144800 0
22.352 SPLEN20128000 0 2.403 SPLEN20171210 0 54.539 SPLEN20264110 0
80.173 TBAES20000590 0 84.801 TBAES20002550 0 100 TBAES20003150 0
100 TESTI20334410 0 15.439 TESTI20432750 0 62.244 TRACH20003590 0
20.978 TRACH20084720 0 11.037 UTERU20046640 0 11.937 BEAST20004540
100 0 SPLEN20008740 10.632 0
[0573] TABLE-US-00008 TABLE 6 CloneID CERVX TCERX BGGI120006160 0
18.869 BRAMY20063970 0 59.264 BRHIP20218580 0 70.621 FEBRA20002100
0 14.918 SPLEN20162680 0 9.118 TESTI20214250 0 36.333 CTONG20105080
84.727 0 HCHON20015980 50.212 0 PROST20175290 52.453 0
TESTI20254220 51.293 0 THYMU20279750 82.6 0
[0574] TABLE-US-00009 TABLE 7 CloneID COLON TCOLN ASTRO20001410 0
32.199 BRAWH20162690 0 27.951 CTONG20132220 0 79.674 HCHON20002260
0 17.098 NT2RI20001330 0 54.324 TCOLN20001390 0 100 3NB6910001910
42.978 0 BRAMY20120910 41.689 0 BRAWH20004600 4.285 0 BRCOC20031250
39.895 0 BRCOC20031870 11.042 0 COLON10001350 100 0 COLON20043180
100 0 COLON20093370 100 0 FEBRA20002100 4.963 0 FEBRA20082010
16.836 0 FEBRA20197110 29.691 0 KIDNE20007770 53.588 0
KIDNE20013730 50.02 0 NT2RP70045590 59.84 0 OCBBF20078920 29.908 0
PROST20083600 12.636 0 SPLEN20011410 6.63 0 TRACH20084720 11.015 0
THYMU20271250 1.257 15.18
[0575] TABLE-US-00010 TABLE 8 CloneID NESOP TESOP ASTRO20033160 0
20.183 ASTRO20125520 0 10.113 BRAMY20266850 0 16.957 BRAWH20164460
0 59.524 BRHIP20005340 0 9.367 BRHIP20191490 0 75.561 CTONG20095290
0 43.261 CTONG20143690 0 28.473 CTONG20161850 0 17.787
DFNES20001530 0 21.906 DFNES20071130 0 45.721 FCBBF30123470 0
15.017 FCBBF30175310 0 10.97 FEBRA20095140 0 45.326 HCHON20016650 0
10.558 MESAN20025190 0 31.731 NT2RI20028470 0 8.588 NT2RI20054050 0
1.921 NT2RP70036880 0 5.052 NTONG20009770 0 6.726 NTONG20064840 0
29.574 NTONG20076930 0 48.142 SMINT20042990 0 61.748 SPLEN20008820
0 12.019 SPLEN20128000 0 2.337 SPLEN20149110 0 7.218 STOMA20013890
0 39.515 TESOP20000900 0 100 TESOP20003120 0 66.097 TESOP20004000 0
100 TESOP20005270 0 70.604 TESOP20005690 0 100 TESTI20334410 0
7.508 THYMU20271250 0 2.449 TRACH20141240 0 7.062 UTERU20022940 0
12.42 NESOP10001080 100 0 NT2RI20023160 17.058 0 NTONG20013620
74.273 0 TRACH20077540 31.967 0 NTONG20015870 69.673 12.221
[0576] TABLE-US-00011 TABLE 9 CloneID KIDNE TKIDN ASTRO20008010 0
3.776 ASTRO20181690 0 3.496 BRACE20111830 0 23.795 BRACE20152870 0
8.501 BRACE20237270 0 73.082 BRAMY20147540 0 5.185 BRAMY20286820 0
78.604 BRAWH20015350 0 12.794 BRAWH20096780 0 78.731 BRAWH20132190
0 35.86 BRAWH20182060 0 40.908 BRCAN20060190 0 13.906 BRCOC20004870
0 1.072 BRCOC20176520 0 51.098 BRHIP20000870 0 24.363 BRHIP20198190
0 32.096 BRHIP20233090 0 43.183 BRHIP30001110 0 3.79 BRSSN20015790
0 49.863 BRSTN20000580 0 8.929 CTONG10000940 0 1.442 CTONG20098440
0 66.526 CTONG20150910 0 6.012 CTONG20165050 0 66.526 DFNES20014040
0 38.579 DFNES20037420 0 38.579 FCBBF10000770 0 2.998 FCBBF30083820
0 39.87 FCBBF30247930 0 59.143 FEBRA20037500 0 6.758 FEBRA20072120
0 14.531 FEBRA20080810 0 2.621 FEBRA20086620 0 17.626 FEBRA20140100
0 59.757 FEBRA20144170 0 1.999 FEBRA20176800 0 35.198 HCHON20008320
0 13.096 HCHON20059870 0 36.909 HLUNG10000550 0 2.004 MESAN20106640
0 32.125 NT2RI20025400 0 6.399 NT2RI20076290 0 7.462 NT2RI20091940
0 3.638 OCBBF20019830 0 26.741 OCBBF20022900 0 37.332 OCBBF20039250
0 3.084 OCBBF20080050 0 11.755 OCBBF20097720 0 8.718 OCBBF20125530
0 4.341 OCBBF20130110 0 27.949 OCBBF20140640 0 5.056 OCBBF20173980
0 9.523 PANCR10000910 0 1.114 PROST20087700 0 2.887 PUAEN20044000 0
26.668 SPLEN20144520 0 68.029 SPLEN20160980 0 68.029 TKIDN10000010
0 41.198 TKIDN20004640 0 68.029 TKIDN20005210 0 55.069
TKIDN20030590 0 78.393 TKIDN20030620 0 100 TKIDN20047480 0 35.796
TRACH20003590 0 11.039 TRACH20028030 0 7.714 TRACH20183170 0 10.844
TRACH20184490 0 56.123 UMVEN20003540 0 3.049 UTERU20004240 0 3.144
UTERU20055930 0 12.464 ASTRO10001650 7.727 0 ASTRO20108190 2.346 0
BGGI120006160 3.117 0 BRACE20039040 9.038 0 BRAMY20102080 63.37 0
BRAWH20004600 2.128 0 BRAWH20125380 35.37 0 BRAWH20162690 4.596 0
BRHIP20115760 66.835 0 BRHIP20205090 65.282 0 CTONG20052650 65.178
0 CTONG20108210 2.491 0 CTONG20128470 6.004 0 CTONG20133480 19.179
0 CTONG20139070 7.516 0 D9OST20000310 16.47 0 DFNES20001530 11.162
0 FCBBF10001820 59.128 0 FEBRA20002100 4.929 0 HCHON20008980 35.524
0 HCHON20016650 5.38 0 HLUNG20033780 32.277 0 KIDNE20002520 2.979 0
KIDNE20003940 100 0 KIDNE20006780 100 0 KIDNE20007210 73.728 0
KIDNE20007770 19.958 0 KIDNE20008010 100 0 KIDNE20009470 8.811 0
KIDNE20011170 77.71 0 KIDNE20011400 100 0 KIDNE20013730 24.839 0
KIDNE20017130 54.019 0 KIDNE20018730 100 0 KIDNE20018970 100 0
KIDNE20020150 100 0 KIDNE20021680 100 0 KIDNE20021910 24.85 0
KIDNE20021980 100 0 KIDNE20022620 100 0 KIDNE20024830 100 0
KIDNE20027250 35.87 0 KIDNE20027950 100 0 KIDNE20028390 25.593 0
KIDNE20028720 1.993 0 KIDNE20028830 7.907 0 KIDNE20029800 10.988 0
KIDNE20067330 100 0 KIDNE20079440 35.045 0 KIDNE20096280 100 0
KIDNE20096470 100 0 KIDNE20100070 100 0 KIDNE20100840 100 0
KIDNE20101370 100 0 KIDNE20101510 100 0 KIDNE20102650 8.237 0
KIDNE20102710 100 0 KIDNE20104300 33.246 0 KIDNE20106740 100 0
KIDNE20107390 100 0 KIDNE20107500 74.264 0 KIDNE20107620 100 0
KIDNE20109730 100 0 KIDNE20109890 100 0 KIDNE20112000 100 0
KIDNE20115080 65.178 0 KIDNE20118580 100 0 KIDNE20120090 33.186 0
KIDNE20121880 62.256 0 KIDNE20122910 83.085 0 KIDNE20124400 6.171 0
KIDNE20125630 100 0 KIDNE20126010 100 0 KIDNE20126130 100 0
KIDNE20127100 33.012 0 KIDNE20127450 100 0 KIDNE20127750 100 0
KIDNE20130450 100 0 KIDNE20131580 63.24 0 KIDNE20132180 100 0
KIDNE20137340 100 0 KIDNE20138010 100 0 KIDNE20141190 49.697 0
KIDNE20144890 100 0 KIDNE20148900 100 0 KIDNE20163880 100 0
KIDNE20180710 49.105 0 KIDNE20181660 100 0 KIDNE20182690 100 0
KIDNE20186780 100 0 KIDNE20190740 100 0 LIVER20035110 28.683 0
MESAN20025190 16.169 0 NT2RP70043480 7.879 0 PROST20107820 1.696 0
PROST20123530 32.771 0 PROST20161950 20.387 0 PUAEN20030180 46.744
0 SKMUS20003610 3.728 0 SMINT20033400 10.243 0 TBAES20000590 5.253
0 TESTI20044310 29.162 0 TESTI20082330 45.847 0 TRACH20032720
12.917 0 UTERU20099720 12.351 0
[0577] TABLE-US-00012 TABLE 10 CloneID LIVER TLIVE BRAWH20166790
83.525 0 CTONG20103480 15.35 0 HEART20005410 11.598 0 LIVER10001260
66.455 0 LIVER10004790 100 0 LIVER20002160 100 0 LIVER20011130
92.988 0 LIVER20011910 100 0 LIVER20028420 16.548 0 LIVER20035110
71.317 0 LIVER20035680 100 0 LIVER20038540 100 0 LIVER20045650 100
0 LIVER20055200 100 0 LIVER20055440 100 0 LIVER20059810 24.82 0
LIVER20062510 100 0 LIVER20064100 88.658 0 LIVER20064690 100 0
LIVER20075680 100 0 LIVER20080530 100 0 LIVER20084730 100 0
LIVER20085800 100 0 LIVER20087510 75.266 0 LIVER20091180 100 0
NTONG20063010 47.641 0 PROST20087700 6.762 0 PROST20107820 2.108 0
TRACH20005400 12.349 0 ASTRO20001410 0 10.441 ASTRO20125520 0
10.162 BRACE20152870 0 15.788 BRAMY20167060 0 34.076 BRAMY20181220
0 87.217 BRAMY20285160 0 81.346 BRCOC20001860 0 20.45 FEBRA20144170
0 3.712 HLUNG10000550 0 3.721 OCBBF20073540 0 6.907 OCBBF20088220 0
16.388 PLAGE60169420 0 26.895 SMINT20152940 0 54.735 SPLEN20242320
0 45.601 THYMU20000570 0 18.649 TRACH20077540 0 30.987
UTERU20055930 0 15.433 UTERU20065930 0 10.151
[0578] TABLE-US-00013 TABLE 11 CloneID HLUNG TLUNG BRACE20096200
70.38 0 BRAWH20004600 2.238 0 BRAWH20030250 11.121 0 BRCAN20006390
61.519 0 BRCAN20280360 8.855 0 BRHIP20238880 1.35 0 CTONG10000940
1.428 0 CTONG20103480 6.495 0 CTONG20129960 10.709 0 CTONG20155180
48.707 0 FCBBF10001210 36.439 0 FEBRA20144170 1.98 0 FEBRA20197110
7.756 0 HCHON20002260 2.958 0 HHDPC20034390 0.933 0 HLUNG10000550
3.971 0 HLUNG20016330 29.367 0 HLUNG20016770 12.888 0 HLUNG20017120
12.093 0 HLUNG20023340 33.714 0 HLUNG20033780 33.957 0
HLUNG20084390 100 0 IMR3220002430 3.147 0 LIVER20028420 14.004 0
NOVAR20000380 2.278 0 NT2RI20023910 8.923 0 NT2RI20054050 2.059 0
NT2RI20091730 4.091 0 NT2RP70044280 12.369 0 OCBBF20020830 40.304 0
OCBBF20125530 4.302 0 PLACE60004630 28.618 0 PROST20057930 14.383 0
PROST20107820 0.892 0 PROST20185830 33.898 0 PUAEN20030180 12.294 0
SMINT20121220 12.822 0 SPLEN20002220 44.799 0 SPLEN20008740 1.788 0
SPLEN20054290 26.875 0 SPLEN20128000 1.253 0 SPLEN20157300 51.319 0
SPLEN20176200 18.8 0 SPLEN20179180 3.344 0 SPLEN20211940 12.373 0
STOMA20013890 21.183 0 TBAES20000590 5.527 0 TESTI20094230 59.311 0
TESTI20184620 10.365 0 TESTI20334410 8.049 0 THYMU20000570 4.974 0
THYMU20039810 1.915 0 TRACH20007020 14.4 0 TRACH20141240 3.786 0
TRACH20183170 10.745 0 ASTRO20108190 0 13.924 ASTRO20155290 0
38.341 BRHIP20096850 0 73.716 FEBRA20080810 0 14.654 MESAN20014500
0 59.68 SMINT20028820 0 60.089 SPLEN20162680 0 8.941
[0579] TABLE-US-00014 TABLE 12 CloneID NOVAR TOVAR BGGI120006160
21.31 0 BRHIP20005340 8.158 0 BRHIP20191860 47.038 0 HHDPC20001040
44.094 0 NOVAR10000150 72.374 0 NOVAR10000910 46.155 0
NOVAR10001020 99.094 0 NOVAR20000380 14.805 0 NOVAR20003520 100 0
THYMU20271250 4.266 0 ASTRO20141350 0 75.66 BRAMY20157820 0 85.296
BRCOC20001860 0 64.79 HLUNG20016770 0 76.536 NT2RI20054050 0 12.229
NTONG20090600 0 60.694 PROST20087700 0 16.991 PUAEN20015860 0
62.197 SPLEN20029310 0 88.828 TOVAR20004760 0 49.428 TOVAR20005750
0 96.313 TRACH20079690 0 55.276 UTERU20004240 0 18.499
[0580] TABLE-US-00015 TABLE 13 CloneID STOMA TSTOM BRACE20060840 0
65.917 FEBRA20052910 0 77.883 HCHON20002260 0 8.66 HLUNG10000550 0
11.625 NTONG20009770 0 21.112 PROST20107820 0 5.223 THYMU20039810 0
11.216 TSTOM10001860 0 100 TSTOM20001390 0 89.823 TSTOM20003150 0
48.943 TSTOM20005690 0 100 ASTRO20125520 10.059 0 BRACE20039040
17.642 0 BRAMY20124260 42.064 0 BRCOC20031870 10.704 0
BRHIP20191860 13.43 0 CTONG20128470 11.719 0 FEBRA20037500 12.423 0
HCHON20040020 5.343 0 HHDPC10000830 6.661 0 IMR3220002430 5.838 0
KIDNE20007770 12.986 0 NOVAR20000380 4.227 0 NT2RI20054050 1.91 0
NT2RI20091730 7.59 0 PROST20130530 20.156 0 SPLEN20149110 7.179 0
SPLEN20157880 32.942 0 STOMA20001830 100 0 STOMA20005390 100 0
STOMA20005670 100 0 STOMA20006400 100 0 STOMA20006780 100 0
STOMA20006860 100 0 STOMA20008880 100 0 STOMA20010250 100 0
STOMA20013890 39.303 0 STOMA20026880 100 0 STOMA20032890 100 0
STOMA20034770 100 0 STOMA20036460 100 0 STOMA20046680 100 0
STOMA20048520 100 0 STOMA20048840 100 0 STOMA20051200 85.988 0
STOMA20056640 100 0 STOMA20056670 100 0 STOMA20057820 91.236 0
STOMA20062130 100 0 STOMA20062290 40.913 0 STOMA20063250 100 0
STOMA20063980 100 0 STOMA20064470 100 0 STOMA20067800 59.113 0
STOMA20069040 100 0 STOMA20072690 100 0 STOMA20076800 100 0
STOMA20077450 100 0 STOMA20080500 100 0 STOMA20083610 100 0
STOMA20086140 100 0 STOMA20088380 100 0 STOMA20092530 100 0
STOMA20092560 100 0 STOMA20092890 39.042 0 TESTI20184620 19.231 0
TRACH20003590 40.588 0 TRACH20183170 19.936 0 PROST20083600 12.248
38.653 TRACH20068660 6.753 21.311
[0581] TABLE-US-00016 TABLE 14 CloneID UTERU TUTER DFNES10001850 0
29.393 NT2RI20023910 0 18.073 SMINT20144800 0 35.406 SPLEN20162680
0 9.628 TOVAR20004760 0 50.572 TUTER20002830 0 100 ASTRO20008010
1.217 0 ASTRO20033160 10.555 0 ASTRO20058630 4.534 0 ASTRO20105820
20.644 0 ASTRO20108190 3.21 0 BRACE20039040 3.092 0 BRACE20057190
3.542 0 BRACE20060840 3.661 0 BRACE20111830 7.667 0 BRACE20223330
10.589 0 BRAMY20266850 2.956 0 BRAWH20113430 8.367 0 BRAWH20126980
22.868 0 BRCOC20031870 0.938 0 BRCOC20107300 12.892 0 BRCOC20121720
6.71 0 BRCOC20155970 25.187 0 BRHIP20105710 18.366 0 BRHIP20191490
13.172 0 BRHIP20207990 12.072 0 BRHIP20217620 6.646 0 BRHIP20222280
10.898 0 BRHIP20238880 0.439 0 BRHIP20249110 11.054 0 BRSSN20018690
3.6 0 BRTHA20000570 51.819 0 CTONG10000940 0.464 0 CTONG10002770
24.668 0 CTONG20095290 7.541 0 CTONG20099380 23.863 0 CTONG20103480
6.336 0 CTONG20108210 2.557 0 CTONG20118250 10.239 0 CTONG20129960
3.482 0 CTONG20131560 24.668 0 CTONG20139070 2.571 0 CTONG20139340
8.273 0 CTONG20143690 4.963 0 CTONG20160560 2.372 0 D3OST30002580
22.242 0 FCBBF10000240 5.237 0 FCBBF10001820 10.114 0 FCBBF10003670
1.812 0 FCBBF10004120 2.308 0 FCBBF10005740 4.952 0 FCBBF30175310
1.912 0 FCBBF30240020 6.769 0 FCBBF30246230 6.682 0 FCBBF40001420
4.36 0 FEBRA20002100 0.843 0 FEBRA20004620 6.733 0 FEBRA20018280
6.489 0 FEBRA20025270 3.416 0 FEBRA20034360 6.63 0 FEBRA20037500
19.596 0 FEBRA20080810 0.845 0 FEBRA20082100 15.999 0 FEBRA20144170
1.288 0 FEBRA20225040 1.959 0 HCHON20002260 0.962 0 HCHON20007380
3.551 0 HCHON20015980 5.796 0 HCHON20016650 1.84 0 HCHON20022470
3.348 0 HCHON20040020 0.936 0 HCHON20076500 7.263 0 HEART20072310
11.555 0 HHDPC20034390 1.517 0 HLUNG10000550 1.937 0 HLUNG20016770
4.191 0 KIDNE20131580 21.635 0 LIVER20028420 9.107 0 MAMGL10000830
0.346 0 MESAN20171520 24.337 0 NOVAR10000150 3.622 0 NOVAR10000910
2.31 0 NT2NE20053580 24.761 0 NT2NE20159740 9.111 0 NT2NE20174920
20.127 0 NT2RI20023160 0.956 0 NT2RI20041880 3.425 0 NT2RI20054050
1.004 0 NT2RI20076290 2.404 0 NT2RI20273230 39.625 0 NT2RP60000770
30.666 0 NT2RP60000850 11.032 0 NT2RP70036880 0.881 0 NT2RP70043480
2.695 0 NT2RP70045590 10.166 0 NT2RP70056750 10.406 0 NT2RP70062230
5.039 0 NT2RP70081610 7.488 0 OCBBF10001750 8.591 0 OCBBF20006770
19.428 0 OCBBF20032460 11.672 0 OCBBF20039250 0.994 0 OCBBF20047570
2.956 0 OCBBF20054760 16.727 0 OCBBF20059560 3.386 0 OCBBF20068490
2.41 0 OCBBF20080050 3.787 0 OCBBF20094240 8.655 0 OCBBF20097720
1.404 0 OCBBF20103130 16.359 0 OCBBF20105570 43.708 0 OCBBF20140640
3.258 0 OCBBF20173980 3.068 0 OCBBF20180120 10.043 0 OCBBF20188730
6.611 0 OCBBF20189560 2.019 0 PEBLM20044520 6.439 0 PLACE60060420
6.493 0 PROST20087700 0.93 0 PROST20107820 0.29 0 PROST20149160
4.345 0 PROST20159240 8.082 0 PROST20176170 25.167 0 PROST20189770
15.499 0 PUAEN20003740 1.145 0 PUAEN20015860 3.406 0 SKMUS20003610
1.275 0 SKNSH20008190 5.937 0 SKNSH20080430 12.076 0 SMINT20026890
51.875 0 SMINT20029760 6.221 0 SMINT20068010 19.209 0 SMINT20110330
25.261 0 SMINT20121220 4.169 0 SPLEN20008390 10.886 0 SPLEN20011410
2.253 0 SPLEN20054290 17.478 0 SPLEN20128000 0.407 0 SPLEN20140800
5.651 0 SPLEN20145720 7.423 0 SPLEN20169720 4.837 0 SPLEN20179180
3.262 0 SPLEN20193110 57.827 0 SPLEN20194050 3.416 0 SPLEN20211940
8.047 0 SPLEN20212730 17.589 0 SPLEN20225220 1.691 0 TBAES20000590
1.797 0 TESTI20061110 24.59 0 TESTI20116830 38.615 0 TESTI20184620
3.37 0 TESTI20208710 64.596 0 TESTI20211240 6.816 0 TESTI20213580
40.357 0 TESTI20214250 4.107 0 TESTI20334410 2.618 0 TESTI20369130
24.204 0 TESTI20369690 4.285 0 TESTI20391770 4.943 0 THYMU20039810
2.491 0 THYMU20216840 58.853 0 THYMU20240710 39.309 0 TRACH20003590
3.557 0 TRACH20032720 4.419 0 TRACH20033230 2.123 0 TRACH20141240
3.693 0 TRAGH20149970 25.316 0 UMVEN10001860 0.63 0 UTERU20000740
62.692 0 UTERU20004240 1.013 0 UTERU20006290 100 0 UTERU20020010
40.126 0 UTERU20022940 2.165 0 UTERU20030570 3.085 0 UTERU20040610
100 0 UTERU20046640 4.048 0 UTERU20046980 100 0 UTERU20050690
64.596 0 UTERU20054460 24.816 0 UTERU20055330 100 0 UTERU20055930
4.016 0 UTERU20056010 3.04 0 UTERU20059050 100 0 UTERU20061030 100
0 UTERU20064000 15.228 0 UTERU20064860 51.819 0 UTERU20065930 3.522
0 UTERU20067050 100 0 UTERU20068990 100 0 UTERU20070040 24.856 0
UTERU20070810 17.449 0 UTERU20076390 100 0 UTERU20081300 53.896 0
UTERU20084260 26.26 0 UTERU20094350 12.756 0 UTERU20095380 40.674 0
UTERU20095400 100 0 UTERU20097760 100 0 UTERU20099720 16.901 0
UTERU20101240 100 0 UTERU20114100 100 0 UTERU20115740 100 0
UTERU20116570 100 0 UTERU20118110 100 0 UTERU20118970 100 0
UTERU20119060 16.267 0 UTERU20119680 100 0 UTERU20120310 53.896 0
UTERU20124070 29.356 0 UTERU20126880 51.568 0 UTERU20134910 13.929
0 UTERU20135860 7.858 0 UTERU20143980 100 0 UTERU20144640 16.101 0
UTERU20145480 39.231 0 UTERU20146310 100 0 UTERU20146680 39.231 0
UTERU20150870 100 0 UTERU20151980 100 0 UTERU20158300 58.853 0
UTERU20158800 100 0 UTERU20161570 100 0 UTERU20164260 15.158 0
UTERU20168220 19.178 0 UTERU20176130 12.264 0 UTERU20176320 64.596
0 UTERU20178100 100 0 UTERU20179880 100 0 UTERU20183640 53.896 0
UTERU20185230 40.126 0 UTERU20186740 100 0 UTERU20188110 100 0
UTERU20188810 100 0 BRAWH10000930 2.2 10.279 CT0NG20128470 2.054
38.378 UTERU20006960 3.394 63.416
[0582] TABLE-US-00017 TABLE 15 CloneID NTONG CTONG ADRGL20018300 0
22.262 ASTRO20058630 0 14.161 ASTRO20072210 0 34.963 ASTRO20108190
0 5.013 BRACE20003070 0 2.194 BRACE20039040 0 4.829 BRACE20060720 0
36.712 BRACE20061050 0 39.515 BRACE20210140 0 11.034 BRACE20276430
0 26.828 BRAMY20152110 0 24.194 BRAMY20266850 0 4.616 BRAMY20271400
0 48.032 BRAWH10000930 0 3.436 BRAWH20004600 0 1.137 BRCAN20280360
0 4.497 BRCOC20004870 0 0.54 BRHIP20005340 0 5.1 BRHIP20005530 0
4.786 BRHIP20238880 0 2.741 BRSSN20146100 0 6.65 CTONG10000100 0
12.075 CTONG10000220 0 100 CTONG10000620 0 100 CTONG10000930 0
74.021 CTONG10000940 0 0.725 CTONG10001650 0 100 CTONG10002770 0
38.523 CTONG20002180 0 100 CTONG20004690 0 5.439 CTONG20009770 0
100 CTONG20014280 0 62.446 CTONG20027090 0 4.036 CTONG20028410 0
19.729 CTONG20038890 0 100 CTONG20049410 0 100 CTONG20050280 0
25.499 CTONG20052650 0 34.822 CTONG20052900 0 42.764 CTONG20075860
0 11.194 CTONG20076130 0 16.303 CTONG20077790 0 62.68 CTONG20082690
0 12.672 CTONG20085950 0 100 CTONG20091080 0 44.201 CTONG20091320 0
100 CTONG20092570 0 100 CTONG20092580 0 100 CTONG20092680 0 100
CTONG20092700 0 100 CTONG20093950 0 100 CTONG20095270 0 100
CTONG20095290 0 11.777 CTONG20095340 0 14.323 CTONG20096430 0 100
CTONG20096750 0 100 CTONG20097660 0 100 CTONG20098440 0 33.474
CTONG20099380 0 37.266 CTONG20099550 0 100 CTONG20099630 0 38.502
CTONG20100240 0 100 CTONG20101480 0 100 CTONG20103480 0 13.193
CTONG20105080 0 15.273 CTONG20105660 0 25.256 CTONG20106230 0 100
CTONG20106520 0 29.937 CTONG20108210 0 2.662 CTONG20114290 0 100
CTONG20114740 0 100 CTONG20118150 0 100 CTONG20118250 0 15.991
CTONG20119200 0 100 CTONG20120770 0 100 CTONG20121010 0 29.404
CTONG20121580 0 33.983 CTONG20124010 0 7.835 CTONG20124220 0 69.076
CTONG20124470 0 100 CTONG20124730 0 100 CTONG20125540 0 100
CTONG20125640 0 7.359 CTONG20126070 0 3.221 CTONG20127450 0 10.331
CTONG20128470 0 9.622 CTONG20129960 0 32.63 CTONG20131490 0 24.817
CTONG20131560 0 38.523 CTONG20132220 0 6.999 CTONG20133390 0 100
CTONG20133480 0 10.246 CTONG20133520 0 50.616 CTONG20136300 0 100
CTONG20138030 0 100 CTONG20139070 0 8.031 CTONG20139340 0 12.919
CTONG20139860 0 100 CTONG20140320 0 100 CTONG20140580 0 100
CTONG20141650 0 8.968 CTONG20146300 0 100 CTONG20147050 0 34.963
CTONG20149460 0 100 CTONG20149950 0 100 CTONG20153300 0 52.97
CTONG20153580 0 74.021 CTONG20155180 0 24.734 CTONG20155400 0 100
CTONG20156780 0 62.446 CTONG20158040 0 100 CTONG20158150 0 16.385
CTONG20158660 0 100 CTONG20159530 0 100 CTONG20160560 0 3.704
CTONG20161850 0 19.368 CTONG20162170 0 100 CTONG20163550 0 100
CTONG20164990 0 65.066 CTONG20165050 0 33.474 CTONG20186320 0
14.897 CTONG20200310 0 100 CTONG20265130 0 100 CTONG20267700 0 100
CTONG20273610 0 100 FCBBF10000240 0 12.268 FCBBF10005740 0 3.866
FCBBF30123470 0 4.088 FCBBF30233680 0 9.14 FEBRA20025270 0 5.334
FEBRA20037500 0 6.8 HCHON20002260 0 1.502 HCHON20007380 0 5.546
HCHON20007510 0 6.65 HCHON20015350 0 17.176 HCHON20040020 0 1.462
HHDPC20034390 0 0.474 HLUNG10000550 0 2.016 KIDNE20002520 0 3.184
KIDNE20009470 0 9.415 KIDNE20115080 0 34.822 KIDNE20127100 0 35.274
LIVER20028420 0 3.556 MESAN20029400 0 5.924 NT2RI20023160 0 1.493
NT2RI20023910 0 1.51 NT2RI20091730 0 4.155 NT2RP70043480 0 4.209
NT2RP70078420 0 3.572 NT2RP70081610 0 11.694 OCBBF20006770 0 30.34
OCBBF20059560 0 5.287 OCBBF20073540 0 1.871 OCBBF20094240 0 13.516
OCBBF20108580 0 12.407 PEBLM20044520 0 15.083 PEBLM20071880 0
16.259 PROST20107820 0 0.453 PUAEN20030180 0 6.243 SKNSH20008190 0
4.636 SMINT20023280 0 34.547 SMINT20089170 0 20.839 SPLEN20179180 0
5.094 TESTI20094020 0 17.075 TESTI20094230 0 30.119 TESTI20152460 0
22.051 TESTI20184620 0 5.263 TESTI20211240 0 10.645 TESTI20442760 0
8.832 THYMU20039810 0 0.973 TRACH20028030 0 11.644 TRACH20141240 0
1.923 TSTOM20003150 0 4.245 UTERU20004240 0 1.582 UTERU20055930 0
2.091 UTERU20065930 0 2.75 UTERU20119060 0 12.702 UTERU20124070 0
45.844 BRACE20039440 34.336 0 BRACE20068590 74.88 0 FCBBF30018550
20.639 0 IMR3220002430 6.323 0 KIDNE20028830 16.715 0 NT2RI20028470
9.251 0 NT2RI20054050 2.069 0 NT2RI20086220 23.258 0 NTONG20009770
7.245 0 NTONG20013620 25.727 0 NTONG20028070 86.921 0 NTONG20029480
32.729 0 NTONG20029700 100 0 NTONG20046140 43.643 0 NTONG20048060
51.123 0 NTONG20049910 100 0 NTONG20050620 100 0 NTONG20050860 100
0 NTONG20051530 58.314 0 NTONG20052650 100 0 NTONG20056570 100 0
NTONG20061870 100 0 NTONG20063010 40.505 0 NTONG20064400 100 0
NTONG20064840 31.857 0 NTONG20065010 100 0 NTONG20066460 100 0
NTONG20067090 66.789 0 NTONG20067830 20.865 0 NTONG20070200 100 0
NTONG20070340 52.247 0 NTONG20075220 100 0 NTONG20076930 51.858 0
NTONG20077560 49.744 0 NTONG20083650 100 0 NTONG20088620 100 0
NTONG20090600 20.536 0 NTONG20090680 100 0 NTONG20092290 100 0
NTONG20092330 100 0 OCBBF20068490 14.895 0 SKMUS20001980 23.281 0
SMINT20138900 67.622 0 SPLEN20008390 67.269 0 SPLEN20162680 3.184 0
UTERU20134910 86.071 0 ASTRO20155290 13.655 3.451 FEBRA20080810
10.438 1.319 NT2RP70032610 10.013 27.835 NT2RP70036880 5.442 16.504
NTONG20015870 17.552 0.554 OCBBF20188730 10.213 2.581 SMINT20122910
33.985 8.589 SPLEN20099700 37.585 9.499
[0583] TABLE-US-00018 TABLE 16 CloneID FCBBF FEBRA OCBBF BRACE
BRALZ BRAMY BRAWH BRCAN BRCOC BRHIP BRSSN BRSTN BRTHA 3NB6910001910
0 0 0 0 0 0 6.122 0 0 6.426 0 0 0 ADRGL- 0 0 0 8.483 0 0 0 0 0 0 0
0 0 20018300 ASTRO20001410 0 0 0 0 0 3.06 0 0 0 0 0 0 0
ASTRO20033160 0 0 0 2.094 0 0 2.95 0 0 0 0 0 0 ASTRO20058630 0 0 0
0 0 0 7.603 0 0 0 0 0 0 ASTRO20064750 0 0 0 0 0 7.505 0 0 0 0 0 0
16.519 ASTRO20100720 0 0 0 0 0 0 0 39.838 0 0 0 0 0 ASTRO20141350 0
0 0 0 0 0 0 0 12.305 0 0 0 0 ASTRO20145760 0 0 0 0 0 11.388 0 0 0 0
42.066 0 0 ASTRO20181690 0 0 0 0 0 0.952 0 2.167 0 1.927 0 0 0
BGGI120006160 0 0 0 1.269 0 0.901 0 2.051 0 0 0 3.224 0.991
BRACE20006400 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20011070 0 0 0
10.447 53.184 0 0 0 0 0 0 0 0 BRACE20019540 0 0 0 100 0 0 0 0 0 0 0
0 0 BRACE20027620 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20037660 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20038000 0 0 0 38.906 0 0 0 0 0 0 0 0
30.394 BRACE20038470 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20038480 0 0
0 38.787 0 0 0 0 0 0 0 0 0 BRACE20038850 0 0 0 100 0 0 0 0 0 0 0 0
0 BRACE20039440 0 0 0 0.367 0 2.086 0.518 1.188 1.834 0 1.927 1.867
0 BRACE20039540 0 0 0 16.746 0 0 0 0 0 0 0 0 0 BRACE20050900 0 0 0
52.057 0 0 0 0 0 0 0 0 0 BRACE20051380 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20051690 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20052160 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20053280 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20053480 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20053630 0 0 0
10.086 0 0 0 0 0 0 0 0 0 BRACE20054500 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20055180 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20057420 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20057620 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20057730 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20058580 0 0 0
14.668 0 0 41.331 0 0 21.084 0 0 22.917 BRACE20058810 0 0 0 100 0 0
0 0 0 0 0 0 0
[0584] TABLE-US-00019 TABLE 17 BRACE20060840 0 0 0 2.179 0 3.093 0
14.084 0 0 0 11.067 0 BRACE20060890 0 0 0 54.983 0 0 16.309 0 0 0 0
0 0 BRACE20061050 0 0 0 15.058 0 0 0 0 0 0 0 0 0 BRACE20061740 0 0
0 100 0 0 0 0 0 0 0 0 0 BRACE20062400 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20062740 0 0 0 41.329 0 58.671 0 0 0 0 0 0 0 BRACE20063630 0 0
0 26.312 0 9.338 0 21.263 0 0 0 0 0 BRACE20063780 0 0 0 38.787 0 0
0 0 0 0 0 0 0 BRACE20063800 0 0 0 58.183 0 0 0 0 0 41.817 0 0 0
BRACE20063930 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20064880 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20068590 0 0 0 7.211 0 0 0 0 0 0 0 0 11.267
BRACE20069090 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20081720 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20082950 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20096200 0 0 0 13.619 0 0 0 0 0 0 0 0 0 BRACE20096540 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20097320 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20101700 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20101710 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20106840 0 0 0 38.787 0 0 0 0 0 0 0 0 0
BRACE20107530 0 0 0 13.239 0 0 0 0 66.077 0 0 0 20.684
BRACE20108130 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20108880 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20109370 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20109830 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20114780 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20115450 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20115920 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20116110 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20116460 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20118380 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20121850 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20141080 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20142320 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20147800 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20148210 0 0 0 100 0 0 0 0 0 0 0 0 0
[0585] TABLE-US-00020 TABLE 18 BRACE20148240 0 0 0 100 0 0 0 0 0 0
0 0 0 BRACE20150310 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20151320 0 0 0
11.694 0 0 0 0 58.366 0 0 0 0 BRACE20152870 0 0 0 1.63 0 0 0 0
8.135 0 0 0 2.547 BRACE20153680 0 0 0 41.512 0 0 58.488 0 0 0 0 0 0
BRACE20154120 0 0 0 17.282 0 0 12.174 0 0 0 0 0 0 BRACE20163150 0 0
0 100 0 0 0 0 0 0 0 0 0 BRACE20163350 0 0 0 9.897 0 0 0 0 0 0 0 0 0
BRACE20165830 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20171240 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20172980 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20175870 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20177200 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20179340 0 0 0 13.12 0 0 0 0 0 0 0 33.326 0
BRACE20185680 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20188470 0 0 0
13.846 0 0 39.016 0 0 0 0 0 21.634 BRACE20190040 0 0 0 39.025 0 0 0
0 0 0 0 0 60.975 BRACE20190440 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20192440 0 0 0 28.977 0 0 0 0 0 0 0 0 0 BRACE20195100 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20201570 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20220300 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20223280 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20223330 0 0 0 12.602 0 0 17.756 0 0 18.115 0
0 19.69 BRACE20224480 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20224500 0 0
0 100 0 0 0 0 0 0 0 0 0 BRACE20228480 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20229280 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20230700 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20232840 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20235400 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20237270 0 0 0
14.013 0 0 0 0 0 0 0 0 0 BRACE20238000 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20240740 0 0 0 45.981 0 0 0 0 0 0 0 0 0 BRACE20248260 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20253160 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20253330 0 0 0 100 0 0 0 0 0 0 0 0 0
[0586] TABLE-US-00021 TABLE 19 BRACE20257100 0 0 0 100 0 0 0 0 0 0
0 0 0 BRACE20262930 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20262940 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20266750 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20267250 0 0 0 13.014 0 0 0 0 0 0 0 0 0 BRACE20269200 0 0 0
100 0 0 0 0 0 0 0 0 0 BRACE20269710 0 0 0 100 0 0 0 0 0 0 0 0 0
BRACE20273890 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20274080 0 0 0 100 0
0 0 0 0 0 0 0 0 BRACE20283920 0 0 0 7.236 0 0 0 0 18.058 0 37.945
36.76 0 BRACE20284100 0 0 0 100 0 0 0 0 0 0 0 0 0 BRACE20286360 0 0
0 37.993 48.354 0 0 0 0 13.653 0 0 0 BRACE20287410 0 0 0 100 0 0 0
0 0 0 0 0 0 BRALZ20013500 0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20014450
0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20017430 0 0 0 0 100 0 0 0 0 0 0 0
0 BRALZ20018340 0 0 0 0 76.517 0 0 0 0 0 0 0 23.483 BRALZ20054710 0
0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20058880 0 0 0 0 100 0 0 0 0 0 0 0 0
BRALZ20059500 0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20064740 0 0 0 0 100
0 0 0 0 0 0 0 0 BRALZ20065600 0 0 0 0 100 0 0 0 0 0 0 0 0
BRALZ20069760 0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20073760 0 0 0 0 100
0 0 0 0 0 0 0 0 BRALZ20075450 0 0 0 0 100 0 0 0 0 0 0 0 0
BRALZ20075760 0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20077900 0 0 0 0 100
0 0 0 0 0 0 0 0 BRALZ20077930 0 0 0 0 100 0 0 0 0 0 0 0 0
BRALZ20080310 0 0 0 0 100 0 0 0 0 0 0 0 0 BRALZ20088690 0 0 0 0 100
0 0 0 0 0 0 0 0 BRAMY10001300 0 0 0 0 0 12.137 0 0 0 0 0 0 0
BRAMY10001570 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20000520 0 0 0 0
39.13 21.823 0 0 0 0 0 39.047 0 BRAMY20000860 0 0 0 0 0 100 0 0 0 0
0 0 0 BRAMY20002770 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20004110 0 0 0
4.399 0 18.735 0 0 0 12.647 23.069 0 0 BRAMY20011140 0 0 0 0 0 100
0 0 0 0 0 0 0
[0587] TABLE-US-00022 TABLE 20 BRAMY20025840 0 0 0 0 0 100 0 0 0 0
0 0 0 BRAMY20039260 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20045240 0 0 0
0 0 21.841 0 0 0 0 0 78.159 0 BRAMY20054880 0 0 0 8.088 0 22.964 0
0 40.37 11.626 0 0 0 BRAMY20060920 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20063970 0 0 0 0 0 2.83 0 6.443 0 2.865 10.452 0 0
BRAMY20071850 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20102080 0 0 0 0 0
36.63 0 0 0 0 0 0 0 BRAMY20104640 0 0 0 15.639 0 33.302 11.017 0 0
0 0 0 0 BRAMY20110640 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20111960 0 0
0 0 0 100 0 0 0 0 0 0 0 BRAMY20116790 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20121190 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20121620 0 0 0 0 0
100 0 0 0 0 0 0 0 BRAMY20124260 0 0 0 0 0 6.228 0 0 0 0 0 0 0
BRAMY20134140 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20135900 0 0 0 0 0
43.537 0 0 0 0 0 0 0 BRAMY20136210 0 0 0 0 0 29.482 0 0 0 0 0 0 0
BRAMY20137560 0 0 0 0 0 19.026 0 0 0 0 0 0 0 BRAMY20144620 0 0 0 0
0 49.688 0 0 0 50.312 0 0 0 BRAMY20147540 0 0 0 5.965 5.061 4.234
5.603 12.854 9.924 27.152 10.427 0 12.427 BRAMY20148130 0 0 0 0 0
19.441 0 0 0 0 0 0 0 BRAMY20152110 0 0 0 0 0 13.088 0 0 0 0 0 0 0
BRAMY20153110 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20157820 0 0 0 0 0
7.891 0 0 0 0 0 0 0 BRAMY20160700 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20163250 0 0 0 0 0 3.796 11.304 0 0 3.844 0 0 4.178
BRAMY20163270 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20167060 0 0 0 0 0
4.994 0 0 0 0 0 0 0 BRAMY20167710 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20168920 0 0 0 10.306 0 14.63 14.52 0 0 44.442 0 0 16.102
BRAMY20170140 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20174550 0 0 0 0 0
100 0 0 0 0 0 0 0 BRAMY20178640 0 0 0 0 0 13.922 0 0 0 14.097
51.427 0 0 BRAMY20181220 0 0 0 0 0 12.783 0 0 0 0 0 0 0
BRAMY20182730 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20183080 0 0 0 0 0
100 0 0 0 0 0 0 0
[0588] TABLE-US-00023 TABLE 21 BRAMY20184670 0 0 0 0 0 100 0 0 0 0
0 0 0 BRAMY20195090 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20204450 0 0 0
0 0 100 0 0 0 0 0 0 0 BRAMY20205740 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20210400 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20211390 0 0 0 0 0
25.787 0 0 0 0 0 0 0 BRAMY20211420 0 0 0 38.011 0 26.981 0 0 0 0 0
0 0 BRAMY20213100 0 0 0 0 0 12.518 0 0 0 0 0 0 0 BRAMY20215230 0 0
0 0 0 21.367 0 0 0 0 0 0 0 BRAMY20217460 0 0 0 0 0 100 0 0 0 0 0 0
0 BRAMY20218250 0 0 0 0 0 66.389 0 0 0 33.611 0 0 0 BRAMY20218670 0
0 0 25.113 0 35.65 0 0 0 0 0 0 39.237 BRAMY20229800 0 0 0 0 0
15.383 30.533 0 54.084 0 0 0 0 BRAMY20229840 0 0 0 0 0 100 0 0 0 0
0 0 0 BRAMY20230600 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20231720 0 0 0
0 0 100 0 0 0 0 0 0 0 BRAMY20240040 0 0 0 1.963 0 2.787 0 6.346
9.799 0 0 0 3.067 BRAMY20245300 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20247110 0 0 0 0 0 12.354 0 0 43.436 0 0 44.21 0 BRAMY20247280
0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20248490 0 0 0 0 0 100 0 0 0 0 0 0
0 BRAMY20250240 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20250320 0 0 0 0 0
100 0 0 0 0 0 0 0 BRAMY20252180 0 0 0 0 0 100 0 0 9 0 0 0 0
BRAMY20252720 0 0 0 0 0 47.605 0 0 0 0 0 0 52.395 BRAMY20260910 0 0
0 0 0 100 0 0 9 0 0 0 0 BRAMY20261680 0 0 0 0 0 32.33 32.087 0 9 0
0 0 35.583 BRAMY20266850 0 0 0 0 0 2.497 0 0 0 0 0 0 0
BRAMY20267130 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20268990 0 0 0 0 0
100 0 0 0 0 0 0 0 BRAMY20270730 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20271400 0 0 0 0 0 51.968 0 0 0 0 0 0 0 BRAMY20273960 0 0 0 0
0 100 0 0 0 0 0 0 0 BRAMY20277140 0 0 0 0 0 100 0 0 0 0 0 0 0
BRAMY20277170 0 0 0 0 0 16.593 20.585 0 0 12.601 0 0 50.221
BRAMY20280720 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20284910 0 0 0 0 0
36.15 0 0 0 0 0 0 0
[0589] TABLE-US-00024 TABLE 22 BRAMY20285160 0 0 0 0 0 3.974 0 0 0
0 14.68 0 0 BRAMY20285930 0 0 0 0 0 100 0 0 0 0 0 0 0 BRAMY20286820
0 0 0 0 0 21.396 0 0 0 0 0 0 0 BRAWH20002320 0 0 0 0 0 0 100 0 0 0
0 0 0 BRAWH20012390 0 0 0 0 0 0 7.296 0 0 0 27.156 0 8.091
BRAWH20014920 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20015350 0 0 0 0
5.352 6.965 1.975 15.859 5.247 10.075 16.539 14.243 10.951
BRAWH20015890 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20016660 0 0 0 0 0 0
100 0 0 0 0 0 0 BRAWH20016860 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20017010 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20018730 0 0 0 0 0 0
100 0 0 0 0 0 0 BRAWH20028110 0 0 0 0 31.162 17.379 8.624 0 0
17.598 0 0 9.564 BRAWH20029630 0 0 0 8.469 0 0 11.932 0 0 0 0 0 0
BRAWH20064050 0 0 0 0 0 0 12.977 0 0 13.24 0 0 0 BRAWH20075700 0 0
0 0 0 0 100 0 0 0 0 0 0 BRAWH20096780 0 0 0 0 0 0 21.269 0 0 0 0 0
0 BRAWH20100690 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20101360 0 0 0 0 0
26.605 26.404 0 0 0 0 0 0 BRAWH20103180 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20105840 0 0 0 0 0 0 30.356 69.644 0 0 0 0 0 BRAWH20106180 0 0
0 0 0 0 100 0 0 0 0 0 0 BRAWH20107540 0 0 0 7.94 0 0 11.186 0 0 0 0
40.334 0 BRAWH20110660 0 0 0 0 0 0 21.178 0 0 0 78.822 0 0
BRAWH20110790 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20110960 0 0 0 0 0 0
54.53 0 0 0 0 0 0 BRAWH20111550 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20112940 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20114000 0 0 0 0 0 0
100 0 0 0 0 0 0 BRAWH20117950 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20118230 0 0 0 0 0 0 21.626 0 0 0 0 0 0 BRAWH20122580 0 0 0 0
0 0 100 0 0 0 0 0 0 BRAWH20125380 0 0 0 0 0 0 10.145 0 0 0 18.88 0
0 BRAWH20126190 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20126980 0 0 0 0 0
57.958 19.174 0 0 0 0 0 0 BRAWH20132190 0 0 0 0 35.004 9.761 19.375
0 0 0 0 0 0 BRAWH20137480 0 0 0 0 0 8.068 2.669 6.123 9.455 2.723
9.934 0 2.96
[0590] TABLE-US-00025 TABLE 23 BRAWH20138660 0 0 0 0 0 0 100 0 0 0
0 0 0 BRAWH20139410 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20142340 0 0 0
0 0 0 100 0 0 0 0 0 0 BRAWH20147290 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20149340 0 0 0 0 0 0 35.975 0 0 0 0 0 0 BRAWH20155950 0 0 0 0
0 0 100 0 0 0 0 0 0 BRAWH20158530 0 0 0 0 0 0 100 0 0 0 0 0 0
BRAWH20160280 0 0 0 0 0 50.189 49.811 0 0 0 0 0 0 BRAWH20162690 0 0
0 0.936 0 1.328 1.318 3.025 4.67 0 4.907 0 0 BRAWH20166790 0 0 0
6.839 0 0 9.636 0 0 0 0 0 0 BRAWH20171030 0 0 0 0 0 0 100 0 0 0 0 0
0 BRAWH20173050 0 0 0 0 0 0 100 0 0 0 0 0 0 BRAWH20182060 0 0 0 0 0
0 11.051 0 0 11.275 0 0 36.766 BRAWH20185060 0 0 0 0 0 0 100 0 0 0
0 0 0 BRCAN10001490 0 0 0 0 0 0 0 56.874 0 0 0 0 0 BRCAN20003460 0
0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20006200 0 0 0 0 0 0 0 100 0 0 0 0 0
BRCAN20006390 0 0 0 0 0 0 0 38.481 0 0 0 0 0 BRCAN20054490 0 0 0 0
0 0 0 100 0 0 0 0 0 BRCAN20060190 0 0 0 2.666 13.575 0 0 25.857
26.617 3.833 0 13.546 0 BRCAN20064010 0 0 0 0 0 22.844 0 52.014 0 0
0 0 25.142 BRCAN20071190 0 0 0 0 0 0 0 38.885 0 0 0 61.115 0
BRCAN20091560 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20103740 0 0 0 0 0
30.516 0 69.484 0 0 0 0 0 BRCAN20124080 0 0 0 0 0 0 0 100 0 0 0 0 0
BRCAN20126130 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20143700 0 0 0 0 0 0
0 100 0 0 0 0 0 BRCAN20147880 0 0 0 0 0 0 0 100 0 0 0 0 0
BRCAN20216690 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20224720 0 0 0 0 0 0
0 100 0 0 0 0 0 BRCAN20237240 0 0 0 0 0 0 0 100 0 0 0 0 0
BRCAN20263400 0 0 0 10.726 54.604 0 0 34.67 0 0 0 0 0 BRCAN20273100
0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20273340 0 0 0 0 0 30.516 0 69.484
0 0 0 0 0 BRCAN20273550 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20275130 0
0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20279700 0 0 0 0 0 0 0 100 0 0 0 0
0
[0591] TABLE-US-00026 TABLE 24 BRCAN20280210 0 0 0 0 0 0 0 100 0 0
0 0 0 BRCAN20280400 0 0 0 0 0 0 0 60.666 0 0 0 0 0 BRCAN20283190 0
0 0 0 0 0 0 29.858 0 0 48.439 0 0 BRCAN20283380 0 0 0 0 0 0 0 100 0
0 0 0 0 BRCAN20284600 0 0 0 0 0 0 0 100 0 0 0 0 0 BRCAN20285450 0 0
0 0 0 0 0 38.885 0 0 0 61.115 0 BRCOC10000870 0 0 0 0 0 0 0 0 100 0
0 0 0 BRCOC20001860 0 0 0 4.222 0 0 0 0 10.537 0 0 0 0
BRCOC20004040 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20004870 0 0 0 0 0 0
0 0.665 1.026 0 0 0 0.643 BRCOC20006370 0 0 0 0 0 0 0 0 100 0 0 0 0
BRCOC20008160 0 0 0 0 0 0 22.014 0 77.986 0 0 0 0 BRCOC20008500 0 0
0 0 0 0 0 0 100 0 0 0 0 BRCOC20020850 0 0 0 0 0 0 0 0 100 0 0 0 0
BRCOC20021550 0 0 0 0 0 0 0 0 75.977 0 0 0 0 BRCOC20023230 0 0 0 0
0 0 0 0 100 0 0 0 0 BRCOC20026640 0 0 0 0 0 0 0 0 100 0 0 0 0
BRCOC20027510 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20031000 0 0 0
16.691 0 0 0 0 83.309 0 0 0 0 BRCOC20031250 0 0 0 0 0 0 0 0 20.131
0 0 0 0 BRCOC20031870 0 0 0 0.558 0 0 0.786 1.804 2.786 0 5.854
2.836 0 BRCOC20035130 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20037320 0 0
0 0 0 0 0 0 75.977 0 0 0 0 BRCOC20037400 0 0 0 0 0 0 0 0 100 0 0 0
0 BRCOC20041750 0 0 0 0 0 0 0 0 34.465 0 0 0 0 BRCOC20055420 0 0 0
0 0 17.805 0 0 62.599 0 0 0 19.596 BRCOC20059510 0 0 0 0 0 0 0 0
100 0 0 0 0 BRCOC20077690 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20090520
0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20091960 0 0 0 0 0 0 0 0 100 0 0 0
0 BRCOC20093800 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20099370 0 0 0 0 0
16.189 0 0 56.917 16.392 0 0 0 BRCOC20101230 0 0 0 0 0 0 0 2.513
3.881 0 0 0 0 BRCOC20107300 0 0 0 0 0 0 0 0 38.292 0 0 0 11.987
BRCOC20110100 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20114180 0 0 0 0 0 0
0 0 100 0 0 0 0 BRCOC20117690 0 0 0 0 0 0 0 0 100 0 0 0 0
[0592] TABLE-US-00027 TABLE 25 BRCOC20119960 0 0 0 0 0 0 0 0 100 0
0 0 0 BRCOC20121720 0 0 0 1.996 0 0 0 0 9.965 2.87 0 0 3.119
BRCOC20122290 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20128130 0 0 0 0 0 0
0 39.306 60.694 0 0 0 0 BRCOC20134480 0 0 0 0 0 0 0 0 100 0 0 0 0
BRCOC20135730 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20136750 0 0 0 0 0 0
0 0 100 0 0 0 0 BRCOC20144000 0 0 0 0 0 0 0 0 59.512 0 0 0 0
BRCOC20147480 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20148330 0 0 0 0 0 0
0 0 100 0 0 0 0 BRCOC20155970 0 0 0 0 0 0 0 0 74.813 0 0 0 0
BRCOC20158240 0 0 0 0 0 0 0 0 100 0 0 0 0 BRCOC20176520 0 0 0 0 0 0
0 0 48.902 0 0 0 0 BRCOC20178560 0 0 0 0 0 0 0 0 100 0 0 0 0
BRHIP10001290 0 0 0 0 0 49.688 0 0 0 50.312 0 0 0 BRHIP20000870 0 0
0 0 23.781 6.632 0 0 0 13.429 24.496 0 7.299 BRHIP20001630 0 0 0 0
0 0 37.398 0 0 38.155 0 0 0 BRHIP20096170 0 0 0 0 0 0 0 0 0 100 0 0
0 BRHIP20096850 0 0 0 0 0 0 7.124 0 0 7.269 0 0 7.901 BRHIP20103090
0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20104440 0 0 0 0 0 0 0 0 0 47.917
0 0 52.083 BRHIP20105710 0 0 0 21.859 0 15.515 0 0 0 31.42 0 0 0
BRHIP20106100 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20107440 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20111200 0 0 0 32.686 0 7.734 15.351 0 0
15.661 28.568 0 0 BRHIP20115080 0 0 0 0 0 0 0 0 0 22.032 0 0 23.948
BRHIP20115760 0 0 0 13.607 0 0 0 0 0 19.559 0 0 0 BRHIP20118380 0 0
0 0 0 0 0 0 0 100 0 0 0 BRHIP20118910 0 0 0 0 0 0 0 0 0 60.949 0 0
0 BRHIP20119330 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20121410 0 0 0 0 0
0 0 0 0 47.917 0 0 52.083 BRHIP20123140 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20129720 0 0 0 0 0 0 0 0 0 47.917 0 0 52.083 BRHIP20132860 0 0
0 0 0 0 0 0 0 17.468 0 0 0 BRHIP20135100 0 0 0 0 0 0 0 0 0 100 0 0
0 BRHIP20137230 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20139720 0 0 0 0 0
0 0 0 0 100 0 0 0
[0593] TABLE-US-00028 TABLE 26 BRHIP20140630 0 0 0 0 0 0 0 0 0
36.967 0 0 0 BRHIP20142850 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20143730 0 0 0 0 0 0 0 0 0 34.432 0 0 37.426 BRHIP20143860 0 0
0 0 0 0 0 0 0 55.026 0 0 0 BRHIP20149540 0 0 0 0 0 0 0 0 0 100 0 0
0 BRHIP20153560 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20153600 0 0 0 0 0
0 0 0 0 100 0 0 0 BRHIP20167880 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20169680 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20169900 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20170100 0 0 0 0 0 0 0 0 0 14.025 0 0 0
BRHIP20173150 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20174040 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20175420 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20180140 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20183690 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20186120 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20186500 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20189980 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20190070 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20191490 0 0 0 0 0 0 0 0 0 11.267 0 0 0 BRHIP20191770 0 0 0 0
0 0 0 0 0 100 0 0 0 BRHIP20194940 0 0 0 25.807 0 0 0 0 0 74.193 0 0
0 BRHIP20195890 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20196410 0 0 0 0 0
0 0 0 0 100 0 0 0 BRHIP20205090 0 0 0 0 0 0 0 0 0 19.104 0 0 0
BRHIP20207430 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20207990 0 0 0 3.592
0 15.298 5.061 0 0 36.143 0 0 5.612 BRHIP20208420 0 0 0 0 0 0 0 0 0
100 0 0 0 BRHIP20208590 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20227080 0
0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20230710 0 0 0 0 0 49.688 0 0 0
50.312 0 0 0 BRHIP20232290 0 0 0 0 0 0 0 0 0 15.312 0 0 0
BRHIP20233090 0 0 0 8.28 0 0 11.666 0 0 23.804 0 0 0 BRHIP20234380
0 0 0 0 0 0 0 0 0 26.026 0 0 0 BRHIP20236950 0 0 0 0 0 0 0 0 0
36.438 0 0 0 BRHIP20238600 0 0 0 0 0 0 0 0 0 100 0 0 0
[0594] TABLE-US-00029 TABLE 27 BRHIP20238690 0 0 0 0 0 0 0 0 0
36.661 0 0 39.849 BRHIP20240460 0 0 0 0 0 0 0 0 0 31.291 0 0 0
BRHIP20243470 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20249110 0 0 0 0 0 0
0 0 0 9.456 0 0 0 BRHIP20252450 0 0 0 0 0 0 0 0 0 47.666 0 0 0
BRHIP20253660 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20277620 0 0 0 0 0 0
0 0 0 100 0 0 0 BRHIP20283030 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP20284800 0 0 0 0 0 0 0 0 0 100 0 0 0 BRHIP20285830 0 0 0 0 0 0
0 0 0 12.691 0 0 0 BRHIP20285930 0 0 0 0 0 0 0 0 0 100 0 0 0
BRHIP30004880 0 0 0 0 0 0 0 0 0 100 0 0 0 BRSSN10000920 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSSN20013420 0 0 0 0 0 0 0 0 0 0 100 0 0
BRSSN20014260 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20015030 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSSN20015790 0 0 0 0 0 0 0 0 0 0 50.137 0 0
BRSSN20018690 0 0 0 2.142 0 0 0 6.925 0 0 11.235 0 6.695
BRSSN20028570 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20038200 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSSN20038410 0 0 0 0 0 0 0 0 0 0 100 0 0
BRSSN20039370 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20043040 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSSN20046570 0 0 0 0 0 0 0 0 0 0 85.061 0 0
BRSSN20046790 0 0 0 0 0 0 0 0 0 0 56.646 0 16.878 BRSSN20046860 0 0
0 0 0 0 0 0 0 0 100 0 0 BRSSN20066110 0 0 0 0 0 21.304 0 0 0 0
78.696 0 0 BRSSN20097020 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20101100
0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20105870 0 0 0 16.015 0 0 0 0 0 0
83.985 0 0 BRSSN20105960 0 0 0 0 43.31 12.077 0 0 0 0 44.612 0 0
BRSSN20108300 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20120810 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSSN20121030 0 0 0 0 0 0 0 0 0 0 100 0 0
BRSSN20137020 0 0 0 0 0 0 0 0 33.606 0 35.308 0 0 BRSSN20142940 0 0
0 0 0 0 0 0 0 0 34.652 0 0 BRSSN20146100 0 0 0 5.068 0 3.597 0 0 0
10.927 13.288 0 11.878
[0595] TABLE-US-00030 TABLE 28 BRSSN20151990 0 0 0 16.015 0 0 0 0 0
0 83.985 0 0 BRSSN20159070 0 0 0 0 0 0 0 0 0 0 100 0 0
BRSSN20159820 0 0 0 0 0 0 0 0 0 0 60.467 0 0 BRSSN20169050 0 0 0 0
0 0 0 0 0 0 100 0 0 BRSSN20176820 0 0 0 0 0 0 0 0 0 0 100 0 0
BRSSN20177570 0 0 0 0 0 0 0 0 0 0 100 0 0 BRSSN20187310 0 0 0 0 0 0
0 0 0 0 100 0 0 BRSTN20000580 0 0 0 3.424 0 2.431 0 33.205 25.637 0
8.978 17.396 0 BRSTN20005360 0 0 0 0 0 0 0 0 0 22.055 0 77.945 0
BRTHA20000570 0 0 0 0 0 0 0 0 0 0 0 0 48.181 BRTHA20004740 0 0 0 0
0 0 0 0 0 0 0 0 100 BRTHA20046290 0 0 0 0 0 0 0 0 0 0 0 0 100
BRTHA20046390 0 0 0 0 0 0 0 0 0 0 0 0 100 BRTHA20046420 0 0 0 0 0 0
0 0 0 0 0 0 100 CD34C30001250 0 0 0 0 0 0 0 0 0 2.372 0 0 0
CD34C30004240 0 0 0 0 0 0 0 0 0 2.336 0 0 0 CTONG10000100 0 0 0 0 0
6.532 0 0 0 0 0 0 7.19 CTONG20004690 0 0 0 0 0 0 0 0 10.345 0 0 0 0
CTONG20027090 0 0 0 1.538 0 0 0 0 0 0 0 0 0 CTONG20050280 0 0 0
14.575 0 0 6.845 0 0 0 0 0 7.591 CTONG20076130 0 0 0 0 0 0 0 0 0 0
0 0 9.707 CTONG20077790 0 0 0 0 0 0 0 0 0 0 0 0 37.32 CTONG20095290
0 0 0 0 0 0 0 14.506 0 0 0 0 0 CTONG20095340 0 0 0 16.375 0 0 0 0 0
23.537 28.623 0 8.528 CTONG20099380 0 0 0 0 0 0 0 0 0 0 0 0 22.188
CTONG20106520 0 0 0 0 0 0 0 0 0 0 0 0 35.648 CTONG20118250 0 0 0
6.093 0 0 0 0 0 0 0 0 0 CTONG20121010 0 0 0 0 0 15.907 0 0 0 0 0 0
0 CTONG20127450 0 0 0 0 0 0 0 0 0 5.659 0 0 0 CTONG20128470 0 0 0
1.222 0 0 3.444 0 0 0 0 0 1.91 CTONG20141650 0 0 0 0 0 0 0 0 0 0 0
0 5.339 CTONG20143690 0 0 0 2.954 0 0 0 0 0 4.246 0 0 0
CTONG20153300 0 0 0 0 0 0 28.439 0 0 0 0 0 0 CTONG20155180 0 0 0 0
0 0 26.559 0 0 0 0 0 0 CTONG20158150 0 0 0 6.244 0 0 8.797 0 0 0 0
0 0 CTONG20161850 0 0 0 3.69 0 2.619 0 0 0 0 0 0 0 CTONG20164990 0
0 0 0 0 0 34.934 0 0 0 0 0 0
[0596] TABLE-US-00031 TABLE 29 CTONG20186320 0 0 0 5.677 0 0 0 0 0
0 0 0 0 D3OST10002700 0 0 0 0 0 7.81 0 0 9.153 0 0 0 0
D6OST20003580 0 0 0 0 0 1.432 0 0 0 0 0 0 1.576 D9OST20000310 0 0 0
0 0 0 0 0 16.736 0 0 0 0 D9OST20035800 0 0 0 0 0 6.953 0 0 0 0 0 0
0 DFNES20010910 0 0 0 0 0 0 0 19.689 0 0 0 0 0 DFNES20071130 0 0 0
0 0 0 0 0 0 0 0 0 7.411 HCHON20002260 0 0 0 1.431 0 0 0.403 0.925
2.857 0.411 0 1.454 0 HCHON20003220 0 0 0 0 0 0 10.98 0 0 0 0 0 0
HCHON20010990 0 0 0 0 0 0 0 0 0 2.783 0 0 3.025 HCHON20015350 0 0 0
0 0 0 18.444 0 0 0 0 0 0 HCHON20022470 0 0 0 1.993 10.144 0 5.615 0
9.945 2.864 0 0 9.34 HCHON20067220 0 0 0 0 0 0 0 0 35.892 0 0 0 0
HCHON20067700 0 0 0 0 0 0 2.822 0 0 0 0 0 0 HEART20003060 0 0 0
9.616 0 0 0 0 0 0 0 0 0 HEART20005410 0 0 0 0 0 0 0 3.07 4.74 0 0 0
0 HEART20061950 0 0 0 0 0 0 0 0 0 9.669 0 0 0 HEART20090000 0 0 0
7.336 0 0 0 23.712 0 0 0 0 0 HHDPC10000650 0 0 0 0 0 0 0 0 0 27.988
0 0 0 HHDPC20057940 0 0 0 0 0 8.015 0 0 0 8.116 0 0 8.821
HLUNG20033780 0 0 0 6.571 0 0 0 0 0 0 0 0 0 KIDNE20011170 0 0 0 0 0
0 22.29 0 0 0 0 0 0 KIDNE20027250 0 0 0 7.303 0 0 10.289 23.605 0 0
0 0 11.41 KIDNE20104300 0 0 0 0 0 0 0 21.878 0 0 0 0 10.575
KIDNE20107500 0 0 0 0 0 0 0 0 0 0 0 0 11.811 KIDNE20122910 0 0 0
16.915 0 0 0 0 0 0 0 0 0 KIDNE20127100 0 0 0 0 0 0 0 0 0 0 0 0
10.501 KIDNE20180710 0 0 0 0 50.895 0 0 0 0 0 0 0 0 LIVER10001260 0
0 0 0 0 0 0 0 0 0 28.534 0 0 LIVER20064100 0 0 0 0 0 0 0 0 0 0 0 0
11.342 LIVER20087510 0 0 0 0 0 0 0 0 0 0 0 0 9.629 MAMGL10000830 0
0 0 0.206 0 0 0 0 0 0.296 0 0 0.321 MESAN20031900 0 0 0 0 0 0 0 0 0
0 0 0 19.624 MESAN20036460 0 0 0 0 0 0 0 0 0 0 0 0 23.021
MESAN20106640 0 0 0 6.16 0 0 0 19.91 0 0 0 0 9.624 MESAN20164090 0
0 0 0 0 0 0 38.222 0 0 0 0 0 NOVAR10000150 0 0 0 0 0 0 0 0 10.757 0
0 0 0
[0597] TABLE-US-00032 TABLE 30 NOVAR20000380 0 0 0 3.968 15.711
0.626 1.242 4.275 6.602 0 9.248 17.918 0 NT2NE20010400 0 0 0 11.003
0 15.621 0 0 0 0 0 0 17.192 NT2NE20010490 0 0 0 0 0 0 0 0 0 0 0
31.686 0 NT2NE20021620 0 0 0 0 0 0 0 0 0 0 45.501 0 0 NT2NE20122430
0 0 0 0 0 0 0 0 0 0 0 0 23.43 NT2NE20125050 0 0 0 13.014 0 0 0 0 0
0 0 0 0 NT2NE20174920 0 0 0 0 0 0 0 0 0 0 0 0 18.714 NT2RI20001330
0 0 0 1.819 0 0 0 0 0 0 0 0 0 NT2RI20023590 0 0 0 0 0 0 8.23 0 0 0
0 0 0 NT2RI20041880 0 0 0 0 0 0 0 0 0 0 0 10.353 0 NT2RI20046080 0
0 0 0 0 0 0 8.488 0 0 0 0 0 NT2RI20216250 0 0 0 0 0 0 0 0 0 19.442
0 0 0 NT2RI20252550 0 0 0 0 0 0 0 0 0 0 0 0 37.898 NT2RP60000770 0
0 0 0 0 0 0 0 0 0 0 0 7.128 NT2RP70045590 0 0 0 0 0 0 0 0 0 0 0 0
9.452 NT2RP70063950 0 0 0 0 0 0 0 0 0 17.468 0 0 0 NT2RP70195430 0
0 0 0 38.221 0 0 0 0 10.792 0 0 0 NT2RP70198350 0 0 0 0 0 0 1.042 0
0 0 0 3.758 0 NTONG20028070 0 0 0 0 0 0 0 0 0 0 0 0 13.079
NTONG20046140 0 0 0 0 0 0 0 0 0 0 0 0 6.567 NTONG20064840 0 0 0
3.068 0 0 0 0 0 0 0 0 0 NTONG20067830 0 0 0 0 0 2.853 0 0 0 0 0 0 0
NTONG20077560 0 0 0 4.791 0 0 0 0 0 0 0 0 0 PANCR10000910 0 0 0
0.214 0 0 0 0 0 0 0 0 0 PEBLM20024550 0 0 0 0 0 0 0 0 0 0 33.118 0
0 PEBLM20052820 0 0 0 0 0 11.82 0 0 0 0 0 0 0 PEBLM20074370 0 0 0 0
21.543 0 0 0 0 0 0 0 0 PERIC20004780 0 0 0 7.727 0 0 0 0 0 0 0 0 0
PLACE50000660 0 0 0 0 0 18.438 0 0 0 0 0 32.991 0 PLACE60079250 0 0
0 0 0 0 0 23.248 0 0 0 0 0 PLACE60136720 0 0 0 0 0 27.825 0 0 0 0 0
0 0 PLACE60138830 0 0 0 0 0 0 0 0 0 0 0 0 38.39 PROST20005670 0 0 0
0 0 14.432 0 0 0 0 0 0 0 PROST20050670 0 0 0 11.45 0 0 0 0 0 0 0 0
17.889 PROST20107820 0 0 0 0 0 0 0.243 0 0 0 0 0 0 PROST20111050 0
0 0 25.26 0 0 0 0 0 0 0 0 0 PROST20116600 0 0 0 16.676 0 0 0 0 0 0
0 0 0
[0598] TABLE-US-00033 TABLE 31 PROST20120160 0 0 0 0 0 22.126 0 0 0
0 0 0 0 PROST20123530 0 0 0 0 0 0 0 0 0 0 0 33.893 0 PROST20161950
0 0 0 0 0 0 0 0 0 0 0 21.086 0 PROST20171280 0 0 0 0 0 8.119 0 0 0
0 0 0 0 PROST20175290 0 0 0 1.802 0 0 0 0 0 0 0 0 2.815
PROST20185830 0 0 0 0 0 0 0 0 0 0 0 33.325 0 PROST20191640 0 0 0 0
0 0 3.687 0 0 0 0 0 0 PUAEN20015860 0 0 0 2.027 0 0 0 0 0 2.913 0 0
0 PUAEN20030180 0 0 0 0 0 0 0 0 0 0 0 12.086 3.717 PUAEN20044000 0
0 0 0 0 7.259 0 0 0 0 0 0 0 PUAEN20078980 0 0 0 0 39.038 0 0 0 0 0
0 0 0 PUAEN20085150 0 0 0 13.781 0 0 0 0 0 9.905 0 0 21.533
PUAEN20108240 0 0 0 11.155 0 26.393 5.239 0 0 16.034 0 0 11.619
SKMUS20012010 0 0 0 0 0 1.795 0 0 0 0 0 0 0 SKNSH20062340 0 0 0 0 0
3.527 0 0 0 0 0 0 0 SMINT20013480 0 0 0 0 0 0 0 0 32.864 0 0 0 0
SMINT20042990 0 0 0 6.406 0 0 0 0 0 0 0 0 0 SMINT20053300 0 0 0 0 0
0 0 0 0 0 51.332 0 0 SMINT20076470 0 0 0 0 0 22.212 0 0 0 0 0 0 0
SMINT20092330 0 0 0 16.746 0 0 0 0 0 0 0 0 0 SMINT20101440 0 0 0 0
0 0 0 0 0 0 0 0 23.912 SMINT20121220 0 0 0 0 0 0 0 0 12.384 0 0 0
3.877 SMINT20121950 0 0 0 16.746 0 0 0 0 0 0 0 0 0 SMINT20122910 0
0 0 6.546 0 0 0 0 0 0 0 0 0 SMINT20130320 0 0 0 0 0 12.051 0 0 0 0
0 0 0 SMINT20131810 0 0 0 0 0 22.212 0 0 0 0 0 0 0 SMINT20144800 0
0 0 0 0 0 0 0 5.628 0 5.913 0 0 SMINT20163960 0 0 0 0 0 0 0 0
50.098 0 0 0 0 SPLEN20002220 0 0 0 0 0 0 12.214 0 0 0 0 0 0
SPLEN20008740 0 0 0 0 1.761 0 0.487 0 0 0 0 0 0 SPLEN20011410 0 0 0
0.67 0 0 0 0 0 0.963 0 0 2.094 SPLEN20016260 0 0 0 0 0 0 0 0 0 0 0
67.455 0 SPLEN20027440 0 0 0 0 0 0 2.23 0 7.901 0 0 0 0
SPLEN20029310 0 0 0 0 0 0 4.078 0 0 0 0 0 0 SPLEN20033960 0 0 0 0 0
0 0 0 0 0 0 67.455 0 SPLEN20054290 0 0 0 5.201 0 0 0 0 0 3.738 0 0
4.063 SPLEN20126190 0 0 0 0 0 0 36.501 0 0 0 0 0 0
[0599] TABLE-US-00034 TABLE 32 SPLEN20128000 0 0 0 0 0 0 0 0.784 0
0 0 0 0.379 SPLEN20145720 0 0 0 0 0 0 0 0 22.047 0 0 0 6.902
SPLEN20146450 0 0 0 0 0 0 0 0 0 0 68.148 0 0 SPLEN20147110 0 0 0 0
0 0 2.652 0 0 0 0 0 0 SPLEN20149110 0 0 0 0.749 0 0 0 0 0 0 0 0
2.34 SPLEN20157880 0 0 0 3.436 0 0 0 0 0 0 0 0 5.368 SPLEN20158900
0 0 0 28.977 0 0 0 0 0 0 0 0 0 SPLEN20171210 0 0 0 0 0 15.624 7.753
0 0 0 0 0 8.598 SPLEN20179180 0 0 0 0 0 0 0 0 3.23 0 0 0 0
SPLEN20186430 0 0 0 0 0 0 36.501 0 0 0 0 0 0 SPLEN20204170 0 0 0
9.907 0 0 0 0 0 0 0 50.331 15.479 SPLEN20212730 0 0 0 0 0 0 14.747
0 0 0 0 0 16.354 SPLEN20214580 0 0 0 0 0 0 0 0 0 0 0 0 38.93
SPLEN20250390 0 0 0 28.977 0 0 0 0 0 0 0 0 0 STOMA20051200 0 0 0 0
0 0 0 0 0 0 0 0 14.012 STOMA20062290 0 0 0 0 0 0 6.012 0 0 0 0 0 0
STOMA20092890 0 0 0 4.072 0 0 5.737 0 0 0 0 0 0 SYNOV20003970 0 0 0
0 0 0 0 0 0 48.614 0 0 0 TESOP20005270 0 0 0 0 0 0 0 0 0 0 0 0
11.444 TESTI10000940 0 0 0 0 0 0 0 22.629 0 0 0 0 0 TESTI20001720 0
0 0 0 0 0 0 0 0 0 0 0 9.487 TESTI20002720 0 0 0 6.872 0 0 0 0 0 0 0
0 0 TESTI20004890 0 0 0 0 0 0 0 0 0 0 0 57.966 0 TESTI20011200 0 0
0 0 0 0 0 0 0 0.986 0 0 0 TESTI20035960 0 0 0 0 0 0 0 0 14.759 0 0
0 0 TESTI20037560 0 0 0 0 0 0 0 0 0 0 0 0 11.634 TESTI20044310 0 0
0 0 0 0 8.365 0 0 0 0 0 0 TESTI20061110 0 0 0 14.633 0 0 0 47.3 0 0
0 0 0 TESTI20063830 0 0 0 0 0 4.084 0 0 0 4.135 0 0 0 TESTI20086210
0 0 0 0 0 0 0 0 35.791 0 0 0 0 TESTI20152460 0 0 0 8.403 0 0 0 0 0
0 0 0 0 TESTI20168960 0 0 0 0 0 0 0 0 0 43.832 0 0 0 TESTI20170350
0 0 0 29.776 0 0 0 0 0 42.801 0 0 0 TESTI20208400 0 0 0 11.599 0 0
0 0 0 0 0 0 0 TESTI20213580 0 0 0 0 0 0 0 0 0 0 0 0 37.524
TESTI20214250 0 0 0 1.222 0 0 1.722 0 0 0 0 0 1.909 TESTI20254220 0
0 0 1.762 0 0 0 0 0 0 0 0 0
[0600] TABLE-US-00035 TABLE 33 TESTI20258460 0 0 0 43.347 0 0 0 0 0
20.77 0 0 22.576 TESTI20330310 0 0 0 0 0 0 0 0 0 0 0 0 34.12
TESTI20334410 0 0 0 0 0 0 0 0 0 0 0 0 2.434 TESTI20366910 0 0 0 0 0
0 0 0 0 0 0 84.653 0 TESTI20391770 0 0 0 5.883 0 0 16.578 0 0
21.141 0 0 18.384 TESTI20432750 0 0 0 0 31.972 0 0 0 0 0 0 0 0
TESTI20455620 0 0 0 0 0 0 0 0 0 0 0 84.653 0 THYMU20000570 0 0 0 0
0 0 0 0 0 0 0 0 1.504 THYMU20058070 0 0 0 45.981 0 0 0 0 0 0 0 0 0
THYMU20066100 0 0 0 0 0 0 0 0 0 0 0 0 30.115 THYMU20075320 0 0 0 0
56.448 0 0 0 0 0 0 0 0 ThYMU20081490 0 0 0 0 0 0 0 0 0 0 0 0 6.532
THYMU20100410 0 0 0 0 0 18.787 0 0 0 19.023 0 0 0 THYMU20101920 0 0
0 0 0 0 0 0 0 0 0 0 57.08 THYMU20108310 0 0 0 0 0 0 54.53 0 0 0 0 0
0 THYMU20119390 0 0 0 45.981 0 0 0 0 0 0 0 0 0 THYMU20126900 0 0 0
0 0 3.915 0 0 0 0 0 0 0 THYMU20128260 0 0 0 0 0 22.315 22.147 0 0
22.595 0 0 0 THYMU20169680 0 0 0 0 0 0 0 0 0 7.541 0 0 0
THYMU20193640 0 0 0 29.854 0 0 0 0 0 0 0 0 0 THYMU20209590 0 0 0
7.868 0 0 11.085 25.432 0 0 0 0 12.293 THYMU20235760 0 0 0 0 0 0
15.94 0 0 0 0 57.476 0 THYMU20239430 0 0 0 0 0 0 54.53 0 0 0 0 0 0
THYMU20240710 0 0 0 0 0 33.209 0 0 0 0 0 0 0 THYMU20253250 0 0 0 0
0 13.123 0 29.879 46.138 0 0 0 0 THYMU20286290 0 0 0 0 0 0 0 0 0 0
0 0 20.303 TKIDN10000010 0 0 0 7.899 0 0 0 0 0 0 0 0 12.342
TKIDN20005210 0 0 0 0 0 0 29.753 0 0 15.178 0 0 0 TKIDN20030590 0 0
0 0 0 0 0 0 0 21.607 0 0 0 TRACH20005020 0 0 0 0 0 0 47.167 0 0 0 0
0 0 TRACH20005400 0 0 0 0 0 0 0 0 0 0 0 0 3.16 TRACH20007020 0 0 0
5.573 0 0 0 0 0 0 0 0 0 TRACH20019960 0 0 0 0 0 0 0 67.193 0 0 0 0
0 TRACH20034840 0 0 0 38.787 0 0 0 0 0 0 0 0 0 TRACH20079690 0 0 0
0 0 0 2.538 0 0 0 0 0 0 TRACH20128110 0 0 0 5.533 28.17 0 0 17.886
0 0 0 0 34.582 TRACH20149970 0 0 0 12.555 0 0 14.151 0 0 7.219 0 0
0
[0601] TABLE-US-00036 TABLE 34 TRACH20183170 0 0 0 0 0 0 2.93 0 0 0
0 0 0 UMVEN10001860 0 0 0 0 0 0 0 0.606 0 0 0 0 0 UMVEN20003540 0 0
0 0 0 0 0 1.89 2.918 0 0 2.97 0.913 UTERU20000740 0 0 0 37.308 0 0
0 0 0 0 0 0 0 UTERU20030570 0 0 0 1.836 0 0 0 0 0 0 0 9.326 0
UTERU20054460 0 0 0 0 75.184 0 0 0 0 0 0 0 0 UTERU20055930 0 0 0
1.593 0 3.393 4.49 0 0 0 4.178 4.047 4.979 UTERU20056010 0 0 0 0 0
0 0 5.848 0 2.601 0 0 0 UTERU20064860 0 0 0 0 0 0 0 0 0 0 0 0
48.181 UTERU20065930 0 0 0 1.048 0 5.951 2.953 0 0 1.506 0 0 3.275
UTERU20070040 0 0 0 0 0 0 0 0 0 0 0 75.144 0 UTERU20081300 0 0 0 0
0 0 0 0 0 46.104 0 0 0 UTERU20084260 0 0 0 0 0 0 0 0 0 0 0 0 24.416
UTERU20094350 0 0 0 0 0 5.388 26.737 0 0 16.367 0 0 5.93
UTERU20120310 0 0 0 0 0 0 0 0 0 46.104 0 0 0 UTERU20124070 0 0 0 0
0 24.8 0 0 0 0 0 0 0 UTERU20164260 0 0 0 0 0 0 12.709 0 0 0 0 0
14.093 UTERU20168220 0 0 0 0 0 4.05 10.05 0 0 6.152 0 0 0
UTERU20183640 0 0 0 0 0 0 0 0 0 46.104 0 0 0 ASTRO20032120 27.675 0
0 10.632 0 0 0 0 0 0 0 0 0 ASTRO20125520 2.731 0 0 1.049 0 0 0 0 0
0 0 0 1.639 BRACE20039040 4.789 0 0 3.68 9.367 0 0 0 0 0 0 9.348 0
BRACE20060720 36.414 0 0 13.99 0 0 0 0 0 0 0 0 0 BRACE20062640
15.593 0 0 5.99 0 0 0 0 29.9 0 0 0 9.36 BRACE20090440 18.536 0 0
7.121 0 0 0 0 0 0 0 0 0 BRACE20099570 72.245 0 0 27.755 0 0 0 0 0 0
0 0 0 BRACE20111830 11.876 0 0 22.812 0 6.477 0 0 0 13.116 0 0
14.257 BRACE20142570 22.91 0 0 44.008 0 0 12.401 0 0 0 0 0 0
BRAWH20128270 16.614 0 0 0 0 9.061 8.993 0 31.859 0 33.472 0 0
BRCAN20280360 4.46 0 0 0 8.724 4.865 0 5.539 0 2.463 0 0 0
BRHIP20110800 64.423 0 0 0 0 0 0 0 0 35.577 0 0 0 BRHIP20176420
47.719 0 0 0 0 13.013 12.915 0 0 26.353 0 0 0 BRSSN20003120 19.877
0 0 7.636 0 21.682 10.759 0 0 0 40.045 0 0 CTONG20105660 50.102 0 0
0 0 0 0 0 0 0 0 0 0 CTONG20124010 15.543 0 0 0 0 4.239 0 0 0 0 0 0
0 CTONG20133480 10.163 0 0 0 0 5.543 5.501 0 0 0 0 0 12.201
CTONG20139070 7.966 0 0 4.591 0 2.172 2.156 0 0 0 0 0 2.391
[0602] TABLE-US-00037 TABLE 35 CTONG20160560 3.674 0 0 0 0 0 3.977
0 0 0 0 0 0 FCBBF10001210 18.354 0 0 0 0 10.01 0 0 35.196 0 0 0 0
FCBBF10001550 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF10001710 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF10001820 15.666 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF10002430 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF10002700 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF10002800 10.435 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF10003220 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF10003740 73.865 0 0
0 0 0 0 0 0 0 0 0 0 FCBBF10003760 78.7 0 0 0 0 0 21.3 0 0 0 0 0 0
FCBBF10005060 34.365 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF10005460 100 0 0
0 0 0 0 0 0 0 0 0 0 FCBBF10005500 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF20006780 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20014270 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF20023700 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF20032970 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20035280 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF20042170 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF20042560 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20051220 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF20054280 72.245 0 0 27.755 0 0 0 0 0 0 0 0 0
FCBBF20056370 5.134 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20064520 100 0 0 0
0 0 0 0 0 0 0 0 0 FCBBF20067810 11.69 0 0 0 0 6.376 0 0 0 0 0 0
7.017 FCBBF20071860 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF20072650 100 0
0 0 0 0 0 0 0 0 0 0 0 FCBBF20076330 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30008470 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30010810 9.702 0 0
1.864 9.488 2.646 0 0 0 0 0 0 5.824 FCBBF30012350 100 0 0 0 0 0 0 0
0 0 0 0 0 FCBBF30012810 37.617 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30015940 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30019120 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF30024750 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30028180 64.881 0 0 0 0 0 35.119 0 0 0 0 0 0
[0603] TABLE-US-00038 TABLE 36 FCBBF30033050 100 0 0 0 0 0 0 0 0 0
0 0 0 FCBBF30039020 43.392 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30052180
100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30054440 100 0 0 0 0 0 0 0 0 0 0 0
0 FCBBF30057290 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30062880 100 0 0 0
0 0 0 0 0 0 0 0 0 FCBBF30070770 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30071520 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30078290 20.784 0 0
0 0 0 0 0 0 0 0 0 0 FCBBF30083620 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30123470 4.055 0 0 0 0 0 0 0 7.775 0 8.169 0 2.434
FCBBF30170590 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30172550 64.423 0 0
0 0 0 0 0 0 35.577 0 0 0 FCBBF30175310 2.962 0 0 0 5.793 0 3.207
3.678 0 0 0 0 3.556 FCBBF30178730 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30190850 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30195640 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF30199610 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30215060 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30225660 64.881 0 0
0 0 0 35.119 0 0 0 0 0 0 FCBBF30240960 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF30242250 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30243640 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF30247930 29.517 0 0 11.34 0 0 0 0 0 0 0 0 0
FCBBF30252520 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30252800 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF30252850 44.606 0 0 0 0 0 0 55.394 0 0 0 0 0
FCBBF30262510 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30266780 100 0 0 0 0
0 0 0 0 0 0 0 0 FCBBF30266920 29.977 0 0 11.517 0 0 0 0 0 0 0
58.507 0 FCBBF30278630 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30279030
100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30281880 100 0 0 0 0 0 0 0 0 0 0 0
0 FCBBF30284720 100 0 0 0 0 0 0 0 0 0 0 0 0 FCBBF30285280 100 0 0 0
0 0 0 0 0 0 0 0 0 FCBBF40001730 100 0 0 0 0 0 0 0 0 0 0 0 0
FCBBF40005480 27.002 0 0 10.374 0 14.727 0 0 0 0 0 0 0
[0604] TABLE-US-00039 TABLE 17 HCHON20007380 5.501 0 0 0 0 0 0 0 0
0 11.082 0 0 HEART20072310 8.949 0 0 0 0 4.881 0 0 0 4.942 0 0 0
HHDPC20068620 13.827 0 0 0 0 7.541 0 0 0 0 0 0 0 HLUNG20023340
16.982 0 0 0 0 0 0 0 0 0 0 0 0 KIDNE20017130 28.625 0 0 0 0 0 0 0 0
0 0 0 0 KIDNE20028830 8.38 0 0 0 0 0 0 5.203 0 0 8.442 8.178 0
MESAN20014500 5.328 0 0 6.141 0 0 0 0 0 0 0 0 0 NT2RP70072690
43.392 0 0 0 0 0 0 0 0 0 0 0 0 NT2RP70137640 20.975 0 0 0 0 0 0 0 0
11.583 0 0 0 NTONG20067090 16.742 0 0 0 0 0 0 0 0 0 0 0 0
PLACE60004630 14.415 0 0 0 0 0 0 17.901 0 0 0 0 0 PROST20083600
3.325 0 0 2.555 0 0 1.8 0 0 1.836 0 0 3.992 PROST20189770 24.007 0
0 0 0 0 0 0 0 0 0 0 14.411 RECTM20003490 7.826 0 0 0 0 0 0 0 0 0 0
0 0 SKNSH20008190 4.598 0 0 1.767 8.994 12.539 2.489 0 0 0 0 0 8.28
SMINT20115880 34.363 0 0 0 0 0 0 0 0 0 0 0 0 SPLEN20169720 3.746 0
0 2.878 0 0 0 0 0 2.069 0 0 0 SPLEN20194050 2.646 0 0 1.016 0 7.215
1.432 6.571 5.073 1.461 0 0 1.588 SPLEN20284240 51.503 0 0 0 0 0 0
0 0 0 0 0 0 TESTI20083940 73.865 0 0 0 0 0 0 0 0 0 0 0 0
TESTI20213150 37.439 0 0 0 0 0 0 0 0 0 0 0 0 TESTI20254540 20.808 0
0 0 0 0 0 0 0 0 0 0 12.49 TESTI20265250 16.076 0 0 3.088 0 0 0 0 0
0 16.193 0 0 TRACH20118940 32.856 0 0 0 0 8.96 0 0 0 0 0 32.063 0
UTERU20145480 60.769 0 0 0 0 0 0 0 0 0 0 0 0 UTERU20146680 60.769 0
0 0 0 0 0 0 0 0 0 0 0 ASTRO20155290 0 9.237 0 0 0 0 0 0 0 0 0 0 0
BRAWH20030250 0 7.559 0 0 10.956 3.055 6.064 0 0 0 11.285 0 0
BRAWH20113430 0 17.488 0 9.958 0 0 7.015 0 0 7.157 0 0 7.779
BRAWH20122770 0 71.37 0 0 0 0 28.63 0 0 0 0 0 0 BRHIP20005340 0
0.853 0 0 0 0 0.342 0 0 0.349 0 0 0 BRHIP30001110 0 2.552 0 0.727
3.699 2.063 0 2.349 3.627 3.133 3.81 3.691 3.406 BRSTN20002200 0
8.553 0 0 0 20.742 0 7.871 0 10.501 0 37.113 15.219 CTONG20052900 0
57.236 0 0 0 0 0 0 0 0 0 0 0 CTONG20108210 0 3.563 0 3.55 0 1.44
1.429 0 0 2.187 0 0 3.17 DFNES20031920 0 7.467 0 0 0 3.018 0 0 0 0
0 0 0 FEBRA10001900 0 19.812 0 0 0 0 0 18.233 0 0 0 0 0
[0605] TABLE-US-00040 TABLE 38 FEBRA20003210 0 100 0 0 0 0 0 0 0 0
0 0 0 FEBRA20007620 0 15.507 0 0 0 0 0 0 0 0 0 22.43 0
FEBRA20009090 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20010120 0 100 0 0 0
0 0 0 0 0 0 0 0 FEBRA20017050 0 100 0 0 0 0 0 0 0 0 0 0 0
FEBRA20018280 0 27.125 0 3.861 0 0 0 0 0 0 0 0 0 FEBRA20025270 0
7.139 0 0 0 2.886 0 0 0 0 0 0 0 FEBRA20025520 0 100 0 0 0 0 0 0 0 0
0 0 0 FEBRA20026110 0 54.171 0 0 0 0 21.73 0 0 0 0 0 24.098
FEBRA20026280 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20029860 0 100 0 0 0
0 0 0 0 0 0 0 0 FEBRA20034680 0 100 0 0 0 0 0 0 0 0 0 0 0
FEBRA20037260 0 2.482 0 0.707 3.598 1.003 0 2.285 0 0 0 0 1.104
FEBRA20040530 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20042190 0 70.959 0
0 0 0 0 0 0 29.041 0 0 0 FEBRA20052910 0 9.04 0 0 0 0 0 0 0 0 0
13.076 0 FEBRA20060610 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20072120 0
9.786 0 11.144 0 0 0 0 0 16.019 0 0 4.353 FEBRA20079310 0 100 0 0 0
0 0 0 0 0 0 0 0 FEBRA20082010 0 5.978 0 0 0 0 2.398 0 0 0 0 0 2.659
FEBRA20088360 0 79.225 0 0 0 0 0 0 0 0 0 0 0 FEBRA20090290 0 100 0
0 0 0 0 0 0 0 0 0 0 FEBRA20092890 0 34.98 0 0 50.703 0 0 0 0 14.316
0 0 0 FEBRA20093520 0 70.959 0 0 0 0 0 0 0 29.041 0 0 0
FEBRA20097310 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20113560 0 100 0 0 0
0 0 0 0 0 0 0 0 FEBRA20125070 0 18.603 0 0 26.964 0 0 0 0 0 0 0 0
FEBRA20132740 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20140100 0 40.243 0
0 0 0 0 0 0 0 0 0 0 FEBRA20161120 0 100 0 0 0 0 0 0 0 0 0 0 0
FEBRA20166540 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20167390 0 100 0 0 0
0 0 0 0 0 0 0 0 FEBRA20171380 0 100 0 0 0 0 0 0 0 0 0 0 0
FEBRA20176800 0 23.704 0 0 0 9.581 0 21.815 0 9.701 0 0 0
FEBRA20184330 0 77.838 0 22.162 0 0 0 0 0 0 0 0 0 FEBRA20192420 0
20.225 0 5.758 0 0 0 0 0 8.277 0 0 0 FEBRA20195820 0 100 0 0 0 0 0
0 0 0 0 0 0
[0606] TABLE-US-00041 TABLE 39 FEBRA20196370 0 40.753 0 0 0 0 0 0 0
0 0 0 0 FEBRA20196630 0 21.712 0 0 0 0 0 0 0 0 0 0 0 FEBRA20197110
0 5.271 0 0 0 0 0 4.851 0 0 0 0 2.345 FEBRA20211710 0 26.519 0 0 0
10.719 0 24.406 0 0 0 38.357 0 FEBRA20214970 0 100 0 0 0 0 0 0 0 0
0 0 0 FEBRA20215500 0 77.838 0 22.162 0 0 0 0 0 0 0 0 0
FEBRA20216360 0 50.44 0 14.361 0 0 0 0 0 0 0 0 0 FEBRA20222040 0
100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20223220 0 100 0 0 0 0 0 0 0 0 0 0 0
FEBRA20225040 0 4.094 0 0 0 0 0 3.768 11.636 0 0 0 0 FEBRA20226010
0 77.838 0 22.162 0 0 0 0 0 0 0 0 0 FEBRA20229560 0 100 0 0 0 0 0 0
0 0 0 0 0 FEBRA20229630 0 100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20232850 0
100 0 0 0 0 0 0 0 0 0 0 0 FEBRA20235500 0 40.825 0 0 59.175 0 0 0 0
0 0 0 0 HCHON20040020 0 1.957 0 0 0 1.582 0 0 0 0 0 0 1.741
KIDNE20102650 0 5.89 0 0 0 0 2.363 0 0 0 0 0 0 NT2RP70037240 0
23.02 0 26.217 0 0 0 0 0 0 0 0 0 PEBLM20072960 0 4.311 0 0 0 0 0 0
0 0 0 0 0 PLACE60169420 0 9.752 0 0 0 3.942 3.912 8.975 13.858 0
14.56 0 4.338 SKMUS20003610 0 2.666 0 0 0 1.077 0 2.453 0 0 0 0 0
SMINT20026890 0 2.93 0 10.012 0 1.184 4.702 0 0 0 0 0 1.304
SMINT20033400 0 7.324 0 0 0 2.96 0 0 0 0 0 0 0 SPLEN20020070 0
47.573 0 0 0 19.229 0 0 0 0 0 0 0 SPLEN20079510 0 58.898 0 0 0 0 0
0 0 0 0 0 0 TESTI20001000 0 48.295 0 0 0 39.041 0 0 0 0 0 0 0
TESTI20094020 0 22.853 0 0 0 9.237 0 0 0 0 0 0 0 THYMU20027560 0
18.25 0 0 0 0 0 0 0 0 0 0 0 THYMU20180280 0 74.935 0 0 0 0 0 0 0 0
0 0 0 THYMU20271250 0 0.446 0 2.287 2.587 0.902 0.179 0.411 0 0 0
4.518 0.198 TRACH20003590 0 7.434 0 0 0 0 0 0 0 3.042 0 0 0
UMVEN10001560 0 2.576 0 0 0 0 0 0 0 0 0 0 0 UTERU20022940 0 13.576
0 0 0 0 1.815 0 0 0 0 0 4.026 UTERU20046640 0 4.23 0 0 0 1.71 1.697
0 0 0 0 0 1.882 UTERU20119060 0 17 0 0 0 13.742 13.639 0 0 0 0 0 0
UTERU20144640 0 33.653 0 0 0 0 0 0 0 0 50.246 0 0 UTERU20176130 0
51.268 0 0 0 0 0 0 0 0 0 0 0
[0607] TABLE-US-00042 TABLE 40 ASTR020008010 0 0 1.267 0 0 0 0 0 0
0 0 0 0 BRACE20276430 0 0 17.893 10.223 0 0 0 33.045 0 0 0 0 0
BRAMY20103570 0 0 18.549 21.196 0 30.09 14.931 0 0 15.234 0 0 0
BRAMY20120910 0 0 7.377 0 0 5.983 0 0 0 0 0 0 0 BRAMY20162510 0 0
8.934 5.104 25.986 43.477 0 16.499 0 0 0 0 0 BRAMY20196000 0 0
30.091 0 0 8.135 16.148 0 0 0 0 0 8.954 BRAWH20164460 0 0 10.808 0
0 0 8.7 0 0 0 0 0 0 BRCAN20273640 0 0 7.379 0 10.731 5.985 2.97
20.44 21.042 0 11.054 0 13.174 BRCOC20105100 0 0 14.918 0 0 0 0 0
85.082 0 0 0 0 BRHIP20198190 0 0 10.771 30.77 0 0 8.671 0 0 17.692
0 0 0 BRHIP20222280 0 0 11.352 0 0 0 9.138 20.964 0 9.323 0 0 0
BRHIP20254480 0 0 37.989 0 0 30.812 0 0 0 31.199 0 0 0
BRHIP30004570 0 0 33.739 38.553 0 0 0 0 0 27.708 0 0 0
CTONG20028410 0 0 26.318 15.036 0 0 21.185 0 0 10.807 0 0 0
CTONG20091080 0 0 29.481 0 0 0 0 0 0 0 0 0 26.317 CTONG20103480 0 0
2.2 7.541 0 1.784 3.542 4.063 0 1.807 6.591 0 3.927 CTONG20126070 0
0 2.148 0 0 0 0 0 0 0 0 0 5.754 CTONG20139340 0 0 8.617 24.615 0 0
6.936 0 0 7.077 0 0 7.692 DFNES20001530 0 0 3.977 0 0 0 0 0 0 0 0 0
3.551 HCHON20008150 0 0 3.469 0 0 2.814 2.793 0 0 0 10.394 0 0
HHDPC20001040 0 0 4.596 1.313 0 0 0 0 0 0 0 0 2.052 HLUNG20016330 0
0 9.947 0 0 0 0 0 0 0 0 0 0 HLUNG20017120 0 0 4.096 0 35.74 0 0 0 0
0 0 0 0 IMR3220002430 0 0 2.132 1.218 0 1.729 0 0 0 2.626 0 0 0.951
KIDNE20007210 0 0 26.272 0 0 0 0 0 0 0 0 0 0 KIDNE20021910 0 0
17.71 15.177 0 0 0 0 0 0 0 0 7.905 KIDNE20124400 0 0 2.199 2.513 0
0 0 0 0 3.612 6.588 0 3.926 MESAN10001260 0 0 2.218 7.605 0 0 1.786
0 0 3.644 0 0 1.98 MESAN20029400 0 0 3.951 0 0 0 3.18 0 0 0 0 0 0
MESAN20121130 0 0 7.329 0 0 0 0 0 0 6.019 0 0 6.543 MESAN20153910 0
0 25.095 0 0 0 0 0 0 0 0 0 0 NT2NE20159740 0 0 18.979 21.687 0
7.697 0 0 0 0 0 0 8.471 NT2NE20177520 0 0 29.166 0 0 0 0 0 0 0 0 0
0 NT2RI20086220 0 0 3.92 0 0 0 0 0 0 0 0 0 6.999 NT2RI20250750 0 0
21.061 12.033 0 0 0 0 0 17.297 0 0 18.801 NT2RP60000850 0 0 5.745
3.283 0 4.66 4.625 0 0 0 0 0 5.129 NT2RP70044280 0 0 12.569 7.181 0
6.796 16.862 0 0 6.881 0 0 0
[0608] TABLE-US-00043 TABLE 41 NT2RP70056750 0 0 7.226 8.256 0
5.861 11.633 0 0 8.901 0 0 3.225 NT2RP70081610 0 0 15.599 4.456 0 0
0 0 0 6.405 0 0 0 NTONG20009770 0 0 2.442 0 0 0 0 2.255 3.482 0 0 0
0 OCBBF10000540 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF10001750 0 0
17.896 5.112 0 7.258 0 0 0 0 0 0 0 OCBBF20006770 0 0 20.236 0 0
16.413 0 0 0 0 0 0 0 OCBBF20013890 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20019830 0 0 8.974 0 0 0 0 0 0 0 0 0 0 OCBBF20020150 0 0
17.182 9.817 0 0 0 0 0 0 0 0 15.338 OCBBF20020830 0 0 27.302 0 0 0
0 25.211 0 0 0 0 0 OCBBF20023570 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20028050 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20028650 0 0 65.522
0 0 0 0 0 0 0 0 0 0 OCBBF20029800 0 0 54.907 0 0 0 0 0 0 45.093 0 0
0 OCBBF20030280 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20030910 0 0 100 0
0 0 0 0 0 0 0 0 0 OCBBF20035930 0 0 55.403 0 0 0 44.597 0 0 0 0 0 0
OCBBF20037440 0 0 52.585 0 0 0 0 0 0 0 0 0 0 OCBBF20041680 0 0 100
0 0 0 0 0 0 0 0 0 0 OCBBF20045330 0 0 25.025 0 0 0 0 0 0 0 74.975 0
0 OCBBF20046120 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20046470 0 0 100 0
0 0 0 0 0 0 0 0 0 OCBBF20046690 0 0 54.907 0 0 0 0 0 0 45.093 0 0 0
OCBBF20048660 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20050770 0 0 100 0 0
0 0 0 0 0 0 0 0 OCBBF20051610 0 0 54.907 0 0 0 0 0 0 45.093 0 0 0
OCBBF20053430 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20053490 0 0 100 0 0
0 0 0 0 0 0 0 0 OCBBF20053730 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20054200 0 0 78.844 0 0 0 21.156 0 0 0 0 0 0 OCBBF20054760 0 0
5.808 0 0 4.71 0 0 0 0 0 0 0 OCBBF20060300 0 0 100 0 0 0 0 0 0 0 0
0 0 OCBBF20062140 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20062410 0 0 100
0 0 0 0 0 0 0 0 0 0 OCBBF20066390 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20071210 0 0 52.585 0 0 0 0 0 0 0 0 0 0 OCBBF20071840 0 0 100
0 0 0 0 0 0 0 0 0 0
[0609] TABLE-US-00044 TABLE 42 OCBBF20072240 0 0 11.73 6.702 0 0
9.442 0 0 0 0 0 0 OCBBF20073540 0 0 1.248 0.713 0 1.012 3.014 2.305
0 0 0 0 1.114 OCBBF20074140 0 0 59.836 0 0 0 0 0 0 0 0 0 0
OCBBF20076220 0 0 4.561 2.606 0 0 0 0 0 0 0 0 0 OCBBF20079310 0 0
100 0 0 0 0 0 0 0 0 0 0 OCBBF20079460 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20081380 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20082830 0 0 100 0 0
0 0 0 0 0 0 0 0 OCBBF20085200 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20086400 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20086910 0 0 100 0 0
0 0 0 0 0 0 0 0 OCBBF20088140 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20088220 0 0 2.961 0 0 0 0 0 0 0 0 0 0 OCBBF20091150 0 0 100 0
0 0 0 0 0 0 0 0 0 OCBBF20100400 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20103130 0 0 34.079 0 49.562 0 0 0 0 0 0 0 0 OCBBF20104040 0 0
100 0 0 0 0 0 0 0 0 0 0 OCBBF20105570 0 0 22.763 13.005 0 0 0 0 0 0
0 0 0 OCBBF20107090 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20107920 0 0
100 0 0 0 0 0 0 0 0 0 0 OCBBF20108580 0 0 33.1 4.728 0 0 13.322 0 0
20.388 0 0 0 OCBBF20108630 0 0 55.216 0 0 44.784 0 0 0 0 0 0 0
OCBBF20109310 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20111770 0 0 100 0 0
0 0 0 0 0 0 0 0 OCBBF20116850 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20118970 0 0 21.447 0 0 17.395 0 0 61.158 0 0 0 0
OCBBF20120390 0 0 9.527 3.266 0 7.727 26.074 0 0 31.296 0 0 22.111
OCBBF20121390 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20122620 0 0 36.036
0 0 0 29.008 0 0 0 0 0 0 OCBBF20124360 0 0 59.836 0 0 0 0 0 0 0 0 0
0 OCBBF20127040 0 0 25.938 14.819 0 0 0 0 0 21.301 0 0 0
OCBBF20127140 0 0 7.211 4.12 0 0 0 0 0 0 0 0 0 OCBBF20127550 0 0
100 0 0 0 0 0 0 0 0 0 0 OCBBF20128120 0 0 25.584 0 74.416 0 0 0 0 0
0 0 0 OCBBF20129360 0 0 55.403 0 0 0 44.597 0 0 0 0 0 0
OCBBF20130910 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20132850 0 0 63.64
36.36 0 0 0 0 0 0 0 0 0
[0610] TABLE-US-00045 TABLE 43 OCBBF20140890 0 0 24.517 0 0 19.885
19.735 0 0 0 0 0 0 OCBBF20145760 0 0 4.539 2.593 0 0 0 0 0 3.728 0
0 4.052 OCBBF20148280 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20151150 0 0
44.332 12.664 0 0 0 0 0 0 0 0 0 OCBBF20153340 0 0 65.522 0 0 0 0 0
0 0 0 0 0 OCBBF20153350 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20155060 0
0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20164670 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20170690 0 0 100 0 0 0 0 0 0 0 0 0 0 OCBBF20173060 0 0 55.403
0 0 0 44.597 0 0 0 0 0 0 OCBBF20173250 0 0 100 0 0 0 0 0 0 0 0 0 0
OCBBF20178150 0 0 65.522 0 0 0 0 0 0 0 0 0 0 OCBBF20180840 0 0
16.434 9.389 0 4.443 4.41 0 0 0 0 0 0 OCBBF20186870 0 0 100 0 0 0 0
0 0 0 0 0 0 OCBBF20189560 0 0 2.102 3.604 0 1.705 0 0 0 0 0 0 1.877
PEBLM20044520 0 0 5.03 1.916 0 2.72 10.797 0 0 12.393 0 0 5.987
PEBLM20071880 0 0 10.845 0 0 0 0 0 0 0 0 0 0 PLACE60060420 0 0
6.763 0 0 0 0 0 0 0 0 0 0 PROST20047390 0 0 27.713 10.556 0 0 0 0 0
7.587 0 0 0 PUAEN20003740 0 0 1.59 0.909 1.156 0.322 2.24 0 0 0.653
0 0 1.775 SMINT20029760 0 0 6.48 0 0 0 10.432 0 0 5.322 0 0 0
SPLEN20008820 0 0 2.182 0 0 0 0 0 0 0 0 0 1.948 SPLEN20084600 0 0
1.627 0 0 0 0 0 0 2.673 0 0 0 SPLEN20095550 0 0 10.552 0 0 0 0 0 0
0 0 0 9.419 SPLEN20099700 0 0 12.671 0 0 0 0 0 0 5.203 0 0 0
SPLEN20140800 0 0 11.772 3.363 0 0 0 0 0 0 0 0 0 SPLEN20173510 0 0
7.473 2.135 0 0 9.023 0 9 0 11.195 0 6.671 SPLEN20211220 0 0 20.261
0 0 0 0 0 0 33.279 0 0 18.087 SPLEN20250170 0 0 41.66 0 0 0 0 0 0 0
0 0 0 STOMA20067800 0 0 10.791 0 0 0 0 0 0 0 0 0 0 TESTI20031270 0
0 13.265 0 0 10.759 0 0 0 0 0 0 0 TESTI20116830 0 0 40.221 0 0 0 0
0 0 0 0 0 0 TESTI20121550 0 0 7.961 0 0 0 6.408 0 0 6.538 0 0 7.106
TESTI20234140 0 0 5.057 2.889 0 0 0 0 0 0 0 0 0 TESTI20442760 0 0
11.782 0 0 0 0 10.879 0 0 0 0 10.517 THYMU20039810 0 0 0.649 0 0 0
0.522 0 1.85 2.664 0 0 0.579 THYMU20070360 0 0 19.184 0 0 7.78 0 0
0 0 0 0 8.562
[0611] TABLE-US-00046 TABLE 44 TRACH20033230 0 0 4.422 0 0 7.173
7.119 0 0 9.079 0 0 3.947 TRACH20084720 0 0 3.898 1.114 0 0 0 0
5.558 0 0 0 8.7 BRACE20067430 0 22.168 11.047 15.779 0 4.48 8.892 0
0 4.536 33.098 0 0 BRAWH10000930 0 1.15 2.292 0.655 0 0 0.461 0 0 0
1.717 0 0.511 BRHIP20003120 0 16.166 8.056 9.205 0 6.534 32.424 0 0
13.232 0 0 14.383 BRSSN20152380 0 8.534 8.505 4.859 0 0 10.27 0 0
6.985 12.742 0 0 FEBRA20024100 0 66.741 33.259 0 0 0 0 0 0 0 0 0 0
FEBRA20027810 0 17.057 25.5 43.707 0 6.894 6.842 0 0 0 0 0 0
FEBRA20037500 0 9.102 2.268 2.591 0 1.839 0 0 12.934 1.862 0 0
6.073 FEBRA20082100 0 16.72 8.332 4.761 0 6.758 0 0 23.761 0 0 0 0
FEBRA20098460 0 51.462 25.645 0 0 0 0 0 0 0 0 0 22.893
FEBRA20144170 0 4.038 2.012 0.766 0 3.264 7.559 6.194 3.826 3.856
4.019 5.841 1.198 FEBRA20145780 0 0 27.189 0 0 0 0 0 0 0 0 0 0
FEBRA20233770 0 19.338 9.637 0 28.03 0 15.515 0 27.481 0 0 0 0
HHDPC10000830 0 2.44 2.432 1.389 0 1.972 0 2.246 0 0 3.643 0 2.171
MESAN20025190 0 11.561 5.761 0 0 4.673 0 0 0 4.732 0 0 5.143
MESAN20089360 0 9.917 4.942 5.647 0 12.025 3.978 0 0 4.059 0 0 0
NT2RI20048840 0 11.556 0.96 0 0 0 0 0 0 0.788 2.876 0 0
NT2RP70043480 0 5.634 16.844 0 0 0 0 0 8.006 0 0 0 0 OCBBF20032460
0 24.396 24.315 0 0 9.861 9.786 0 0 19.969 0 0 0 OCBBF20039250 0
2.077 1.035 0 3.011 1.679 0 0 0 0 0 3.004 0 OCBBF20049300 0 25.873
12.893 0 0 0 0 23.811 0 0 0 37.423 0 OCBBF20061720 0 13.071 13.027
0 0 5.283 0 12.029 18.574 0 19.515 0 0 OCBBF20078920 0 21.239 5.292
0 0 0 0 0 0 0 0 15.36 0 OCBBF20084660 0 42.651 10.627 0 0 0 0 0 0 0
31.84 0 0 OCBBF20087010 0 27.016 40.389 0 0 10.92 21.675 0 0 0 0 0
0 PROST20087700 0 1.945 2.907 7.197 0 3.93 4.68 0 0 6.367 2.903
2.813 3.46 PROST20153320 0 6.425 3.202 27.441 0 2.597 10.31 0
18.262 5.259 0 0 0 TRACH20135520 0 25.898 12.906 7.374 0 0 10.389 0
0 31.797 0 0 0 ADIPS20004250 1.434 0 0.964 0 0 0 1.553 0 0 1.584 0
0 0 ASTRO10001650 4.095 0 11.014 0 0 0 0 0 0 0 0 0 0 BRACE20056810
3.689 0 4.961 14.879 0 13.076 16.971 4.581 0 20.37 7.431 7.199
3.321 BRACE20059370 22.318 0 7.504 8.574 0 0 0 0 0 0 0 0 0
BRACE20106690 11.777 0 31.677 9.049 0 0 19.124 0 0 6.504 0 0 7.069
BRACE20210140 10.945 0 14.719 4.205 0 0 17.772 0 0 18.132 0 0 0
BRAWH20103290 13.868 0 6.217 21.311 0 10.085 20.017 0 0 15.317 0 0
11.099 BRAWH20121640 38.493 0 25.884 14.788 0 0 20.835 0 0 0 0 0
0
[0612] TABLE-US-00047 TABLE 45 BRHIP20005530 4.747 0 12.769 1.824 0
2.589 2.57 0 0 5.243 0 0 2.85 BRHIP20217620 5.147 0 3.461 7.91 0 0
8.358 0 0 11.369 0 0 3.09 BRHIP20218580 6.182 0 8.314 4.75 0 3.372
3.346 0 0 3.414 0 0 0 BRHIP20238880 0.68 0 3.2 2.089 0 1.854 2.208
1.688 1.303 0.751 1.369 2.653 4.488 CTONG20075860 11.104 0 14.933 0
0 0 0 0 21.292 0 0 0 0 CTONG20129960 5.394 0 7.255 0 0 0 2.92 0 0 0
0 0 6.476 FCBBF10000240 8.112 0 10.91 0 0 6.637 6.587 0 0 6.72 0
7.916 0 FCBBF10000630 11.049 0 7.43 0 0 6.026 11.962 0 0 6.102 0 0
0 FCBBF10001150 37.553 0 25.252 14.427 0 0 0 0 0 0 0 0 0
FCBBF10004120 3.575 0 7.212 0 0 0 5.806 0 0 0 0 0 2.146
FCBBF10005740 7.67 0 15.473 2.947 0 10.458 8.303 0 7.354 6.353 0 0
4.604 FCBBF20075560 16.883 0 11.353 0 0 0 0 0 0 0 0 0 0
FCBBF30018550 31.042 0 3.479 1.988 0 0 0 0 0 0 0 0 0 FCBBF30025560
59.793 0 40.207 0 0 0 0 0 0 0 0 0 0 FCBBF30086440 15.918 0 10.704 0
0 0 8.616 0 0 0 0 0 0 FCBBF30090690 8.273 0 5.563 6.357 0 22.561
17.913 0 0 4.569 0 0 34.763 FCBBF30189490 52.288 0 17.58 0 0 0 0 0
0 14.438 0 0 15.693 FCBBF30233680 4.533 0 6.096 0 0 0 7.361 0 0
2.503 0 0 2.721 FCBBF30240020 10.485 0 28.201 16.112 0 5.718 5.675
0 0 0 0 0 0 HCHON20007510 6.596 0 4.435 0 0 0 3.57 0 0 0 0 0 3.959
HCHON20016650 2.851 0 5.751 2.191 0 9.329 0 0 0 6.297 0 0 0
HHDPC20095280 12.007 0 8.074 4.613 0 0 0 0 0 6.631 0 0 14.415
KIDNE20002520 1.579 0 6.37 1.213 0 3.444 6.837 0 6.055 3.488 0
3.082 2.843 KIDNE20009470 9.338 0 9.419 0 9.132 0 2.527 0 0 0 0 0
2.803 NT2RI20003480 16.371 0 44.033 0 0 0 0 0 0 0 0 0 0
NT2RI20055790 17.338 0 11.659 0 0 0 0 0 0 19.149 0 0 0
NT2RP70027380 10.635 0 35.756 4.086 0 0 5.756 0 0 5.873 0 0 6.384
NT2RP70032610 2.51 0 3.376 0 0 0 0 0 0 0 0 0 0 NT2RP70062230 7.806
0 10.498 17.994 0 0 4.225 0 0 8.622 15.726 0 0 OCBBF10001850 15.555
0 31.379 0 0 0 4.21 0 0 0 0 0 0 OCBBF20022900 18.632 0 12.529 0 0
20.324 0 0 0 0 0 0 11.184 OCBBF20026630 59.793 0 40.207 0 0 0 0 0 0
0 0 0 0 OCBBF20049840 44.001 0 29.587 0 0 0 0 0 0 0 0 0 26.412
OCBBF20059560 5.245 0 3.527 6.045 10.258 5.721 0 6.513 0 0 10.566 0
3.148 OCBBF20068490 3.734 0 7.532 0 0 0 0 0 0 0 0 0 0 OCBBF20071960
33.142 0 66.858 0 0 0 0 0 0 0 0 0 0 OCBBF20080410 7.723 0 2.597 0 0
0 4.18 0 0 0 0 0 0
[0613] TABLE-US-00048 TABLE 46 OCBBF20094240 13.407 0 9.015 0 0 0 0
0 0 0 0 0 0 OCBBF20097720 4.351 0 5.851 6.686 0 7.119 9.42 2.702
4.172 12.014 0 4.246 1.306 OCBBF20108190 23.173 0 15.583 8.903 0 0
0 0 0 0 0 0 13.91 OCBBF20108430 27.517 0 18.503 0 0 0 0 0 0 0 0 0 0
OCBBF20126780 25.486 0 25.707 29.374 0 0 6.898 0 0 0 0 0 0
OCBBF20130110 13.949 0 9.38 0 0 22.823 0 0 0 7.703 0 0 0
OCBBF20139260 22.924 0 77.076 0 0 0 0 0 0 0 0 0 0 OCBBF20148730
26.202 0 17.619 0 0 0 28.366 0 0 0 0 0 0 OCBBF20149280 59.793 0
40.207 0 0 0 0 0 0 0 0 0 0 OCBBF20164050 71.253 0 28.747 0 0 0 0 0
0 0 0 0 0 OCBBF20173980 2.376 0 9.588 1.826 0 3.888 9.005 0 4.557
6.562 4.788 0 4.28 OCBBF20178880 31.476 0 21.165 0 0 0 17.037 0 0 0
0 0 0 OCBBF20180120 5.185 0 3.487 0 0 2.828 0 0 0 0 0 0 0
OCBBF20188730 5.12 0 5.164 0 0 0 1.386 0 0 2.828 0 0 4.61
PROST20057930 7.245 0 4.872 0 0 0 0 0 0 0 0 0 4.349 SPLEN20162680
3.991 0 2.147 0.307 0 0.435 0 0 0 0 0 1.558 0.479 SPLEN20211940
12.464 0 4.191 0 0 0 3.373 0 0 0 0 0 0 TESTI20184620 5.221 0 7.021
0 0 5.695 2.826 0 0 0 0 0 9.401 TESTI20211240 10.559 0 7.1 0 0
5.759 17.146 0 0 11.662 0 0 0 TESTI20369690 19.913 0 8.927 2.55 0 0
7.186 0 0 3.666 0 0 3.984 THYMU20141670 10.152 0 20.48 0 0 0 0 0 0
0 0 19.814 6.094 TRACH20028030 7.7 0 2.589 2.958 0 4.199 0 0 0 0
23.268 7.514 0 UTERU20099720 13.09 0 39.61 0 0 0 3.543 0 0 3.614 0
0 0 UTERU20135860 24.344 0 8.185 0 0 0 0 0 23.341 13.444 0 0 0
BRACE20057190 5.487 14.807 0 6.324 32.194 5.985 0 6.814 0 3.03
11.054 0 0 BRHIP20191860 7.292 9.84 0 0 0 3.977 0 0 0 4.027 0 0 0
BRHIP20214950 11.849 15.989 0 4.552 46.351 0 0 14.715 0 6.544 0 0 0
FCBBF10003670 5.613 3.787 0 0 0 1.531 0 0 0 1.55 0 0 0
FCBBF10004370 23.626 31.88 0 0 0 0 0 0 0 0 0 0 0 FCBBF30013770
19.023 25.669 0 0 0 0 10.297 0 0 0 0 0 0 FCBBF30095260 21.826
29.451 0 0 0 23.808 11.814 0 0 0 0 0 13.101 FCBBF30246230 41.402
13.966 0 0 0 0 0 0 0 0 0 0 12.426 FEBRA20002100 1.306 3.524 0 0 0 0
0.707 0 0 0.721 0 0 0 FEBRA20034360 10.27 13.858 0 0 0 5.601 0 0
39.387 0 0 0 0 FEBRA20095140 12.239 24.772 0 0 0 3.338 0 0 0 3.379
0 0 0 FEBRA20130190 42.565 57.435 0 0 0 0 0 0 0 0 0 0 0
FEBRA20204060 42.565 57.435 0 0 0 0 0 0 0 0 0 0 0
[0614] TABLE-US-00049 TABLE 47 HCHON20008320 6.536 8.819 0 0 0 0 0
0 0 0 0 0 0 LIVER20028420 3.527 9.518 0 0 0 1.924 0 4.38 0 0 0 0
6.351 TRACH20111130 8.722 23.539 0 3.351 0 0 0 0 0 4.817 0 0 5.236
ASTRO20108190 6.215 3.355 6.687 6.686 0 3.39 4.037 0 2.384 4.119 0
0 0 BRACE20003070 6.528 2.936 10.243 20.064 0 0 1.178 2.702 0 2.403
0 0 1.306 BRACE20060550 7.391 4.987 2.485 4.259 0 2.016 4.001 0 0 0
0 0 2.218 BRAWH20004600 2.255 1.521 1.516 9.097 0 1.23 1.831 1.4
2.162 1.245 4.543 0 4.061 BRAWH20011710 3.423 4.619 15.345 9.644 0
9.334 6.176 1.417 0 1.89 2.299 0 4.794 BRAWH20016620 8.494 34.385
5.712 3.263 0 0 4.598 0 16.288 0 0 0 5.099 BRHIP10001740 9.366
25.278 6.298 3.598 0 5.108 0 0 17.961 5.173 0 18.281 5.622
BRSTN10000830 4.718 1.592 4.759 1.36 0 1.93 0.638 0 2.262 1.303 0
2.302 0 CTONG10000940 10.792 16.505 4.354 1.106 1.407 2.747 0 1.787
4.139 2.781 1.45 0 0.864 CTONG20150910 3.001 2.024 2.018 0.576 0 0
0 0 0 0 0 0 1.801 D3OST10002670 7.978 10.765 5.365 0 0 0 0 9.907 0
0 0 15.57 0 FCBBF10000380 20.755 28.007 41.87 0 0 0 0 0 0 0 0 0 0
FCBBF10000770 19.451 22.208 13.079 0 0 0.816 0 0 0 0 0 0 0.898
FCBBF10003770 39.957 26.958 13.434 0 0 0 0 0 0 0 0 0 0
FCBBF20059090 11.53 15.558 31.013 4.43 0 0 6.241 0 0 19.102 0 0
6.921 FCBBF30016320 2.852 3.848 13.424 1.096 0 0 0 3.542 0 0 0 0 0
FCBBF30016570 8.716 11.762 11.722 11.72 0 4.754 11.795 0 0 9.627
8.78 0 5.232 FCBBF30049550 28.476 19.212 28.723 0 0 0 0 0 0 23.589
0 0 0 FCBBF30083820 19.899 26.851 13.381 0 0 0 0 0 0 0 0 0 0
FCBBF30238870 17.508 23.625 58.866 0 0 0 0 0 0 0 0 0 0
FCBBF40001420 13.508 18.228 18.167 18.164 0 11.051 3.656 0 0 0 0 0
4.054 FEBRA10001880 38.663 15.651 36.398 0 0 2.109 0 0 0 2.135 0 0
0 FEBRA20004620 5.215 7.037 7.013 28.049 0 0 31.051 0 0 8.64 0 0
6.261 FEBRA20080810 1.308 3.531 4.399 1.508 0 2.141 2.124 3.249 0
0.722 2.636 0 0 FEBRA20086620 5.865 11.87 1.972 5.633 0 6.397 11.11
0 0 3.239 0 11.446 1.76 FEBRA20095880 8.952 24.158 42.136 0 0 0
19.382 0 0 0 0 0 5.373 HHDPC20034390 2.819 1.268 5.371 1.625 0
0.513 1.78 0 0 1.816 0.947 0 0.846 HLUNG10000550 1 1.349 4.035 0 0
0 0 0 1.918 1.105 4.029 1.952 1.201 NT2RI20023160 1.481 1.999 0.996
0.569 0 0 0 0 2.84 0.818 0 0 0.889 NT2RI20023910 4.495 4.043 1.007
0 0 4.086 0 1.86 0 0 0 0 1.799 NT2RI20025400 3.194 17.238 2.148
1.227 0 6.967 6.915 7.932 0 5.291 6.434 24.933 1.917 NT2RI20028470
6.957 9.388 7.797 0 0 1.265 0 0 0 1.281 0 0 2.784 NT2RI20054050
0.519 1.4 0.349 0.199 0 0 0.561 0 0 0.573 3.134 0 1.245
NT2RI20076290 3.724 5.025 5.008 1.431 0 4.062 0 0 0 0 0 0 0
[0615] TABLE-US-00050 TABLE 48 NT2RI20091730 2.061 5.561 1.386 0 0
1.124 0 0 0 1.138 0 0 1.237 NT2RI20091940 1.816 9.799 9.767 0 0
0.99 1.965 0 0 1.003 0 0 0 NT2RP70036880 2.728 1.841 8.256 4.193 0
6.696 3.692 0 0 0 0 0 4.913 NT2RP70078420 3.543 4.781 2.383 4.084
6.93 0 0 0 0 1.957 7.139 0 2.127 OCBBF20047570 18.314 30.89 12.315
3.518 8.955 2.497 0 5.686 0 0 0 0 0 OCBBF20080050 11.733 7.916
21.697 6.762 0 6.399 0 0 0 1.62 0 0 0 OCBBF20125530 4.333 11.695
4.371 0 4.238 1.182 0 2.691 0 2.393 4.365 4.229 0 OCBBF20140640
2.523 10.215 3.394 0 0 1.376 0 0 0 4.18 10.167 4.925 0
TRACH20032720 6.845 9.236 9.205 2.63 0 11.2 3.705 8.5 13.125 3.78 0
0 4.109 TRACH20141240 3.814 5.146 2.565 1.465 0 4.16 2.064 0 3.657
0 0 0 3.434 UTERU20004240 3.138 4.234 1.055 3.014 3.069 0.856 1.699
3.897 3.009 0 0 3.062 0
[0616] TABLE-US-00051 TABLE 49 CloneID FEHRT HEART FEHRT20003250
100 0 OCBBF20189560 35.243 0 BRAWH20029630 0 79.6 CTONG20150910 0
5.418 HCHON20007510 0 23.818 HEART20003060 0 90.384 HEART20005410 0
53.555 HEART20021840 0 100 HEART20025980 0 100 HEART20034320 0 100
HEART20037810 0 100 HEART20049400 0 100 HEART20049410 0 63.375
HEART20049800 0 100 HEART20061950 0 63.227 HEART20063340 0 100
HEART20067870 0 100 HEART20067890 0 100 HEART20072310 0 32.316
HEART20074430 0 100 HEART20077670 0 100 HEART20089940 0 100
HEART20090000 0 68.952 HEART20095990 0 100 HLUNG10000550 0 3.611
HLUNG20017120 0 21.996 KIDNE20028390 0 48.974 KIDNE20028830 0
15.131 NTONG20029480 0 44.44 OCBBF10001750 0 48.053 PROST20127800 0
48.531 SKMUS20001980 0 21.074 SKMUS20003610 0 7.134 SMINT20026890 0
7.842 SMINT20121220 0 23.322 SMINT20122910 0 30.763 SMINT20183530 0
65.405 SPLEN20008740 0 3.252 SPLEN20027440 0 14.879 SPLEN20162680 0
2.882 STOMA20062290 0 40.108 TESTI20254220 0 16.559 THYMU20271250 0
3.582 TRACH20141240 0 6.886 UTERU20004240 0 5.666
[0617] TABLE-US-00052 TABLE 50 CloneID FEKID KIDNE ASTRO10001650 0
7.727 ASTRO20108190 0 2.346 BGGI120006160 0 3.117 BRACE20039040 0
9.038 BRACE20060550 0 6.974 BRAMY20102080 0 63.37 BRAWH20004600 0
2.128 BRAWH20125380 0 35.37 BRAWH20162690 0 4.596 BRHIP20115760 0
66.835 BRHIP20205090 0 65.282 BRHIP20238880 0 1.283 CTONG20052650 0
65.178 CTONG20108210 0 2.491 CTONG20128470 0 6.004 CTONG20133480 0
19.179 CTONG20139070 0 7.516 D9OST20000310 0 16.47 DFNES20001530 0
11.162 FCBBF10001820 0 59.128 FEBRA20002100 0 4.929 HCHON20008980 0
35.524 HCHON20016650 0 5.38 HLUNG20033780 0 32.277 KIDNE20002520 0
2.979 KIDNE20003940 0 100 KIDNE20006780 0 100 KIDNE20007210 0
73.728 KIDNE20007770 0 19.958 KIDNE20008010 0 100 KIDNE20009470 0
8.811 KIDNE20011170 0 77.71 KIDNE20011400 0 100 KIDNE20013730 0
24.839 KIDNE20017130 0 54.019 KIDNE20018730 0 100 KIDNE20018970 0
100 KIDNE20020150 0 100 KIDNE20021680 0 100 KIDNE20021910 0 24.85
KIDNE20021980 0 100 KIDNE20022620 0 100 KIDNE20024830 0 100
KIDNE20027250 0 35.87 KIDNE20027950 0 100 KIDNE20028390 0 25.593
KIDNE20028830 0 7.907 KIDNE20029800 0 10.988 KIDNE20067330 0 100
KIDNE20079440 0 35.045 KIDNE20096280 0 100 KIDNE20096470 0 100
KIDNE20100070 0 100 KIDNE20100840 0 100 KIDNE20101370 0 100
KIDNE20101510 0 100 KIDNE20102650 0 8.237 KIDNE20102710 0 100
KIDNE20104300 0 33.246 KIDNE20106740 0 100 KIDNE20107390 0 100
KIDNE20107500 0 74.264 KIDNE20107620 0 100 KIDNE20109730 0 100
KIDNE20109890 0 100 KIDNE20112000 0 100 KIDNE20115080 0 65.178
KIDNE20118580 0 100 KIDNE20120090 0 33.186 KIDNE20121880 0 62.256
KIDNE20122910 0 83.085 KIDNE20124400 0 6.171 KIDNE20125630 0 100
KIDNE20126010 0 100 KIDNE20126130 0 100 KIDNE20127100 0 33.012
KIDNE20127450 0 100 KIDNE20127750 0 100 KIDNE20130450 0 100
KIDNE20131580 0 63.24 KIDNE20132180 0 100 KIDNE20137340 0 100
KIDNE20138010 0 100 KIDNE20141190 0 49.697 KIDNE20144890 0 100
KIDNE20148900 0 100 KIDNE20163880 0 100 KIDNE20180710 0 49.105
KIDNE20181660 0 100 KIDNE20182690 0 100 KIDNE20186780 0 100
KIDNE20190740 0 100 LIVER20035110 0 28.683 MESAN20025190 0 16.169
NOVAR20000380 0 2.166 NT2RI20054050 0 2.936 NT2RP70043480 0 7.879
PROST20107820 0 1.696 PROST20123530 0 32.771 PROST20161950 0 20.387
PUAEN20030180 0 46.744 SKMUS20003610 0 3.728 SMINT20033400 0 10.243
TBAES20000590 0 5.253 TESTI20044310 0 29.162 TESTI20082330 0 45.847
TRACH20032720 0 12.917 UTERU20099720 0 12.351 BRACE20003070 25.479
0 BRCOC20031870 34.023 0 CTONG20125640 85.462 0 FCBBF30016320
33.393 0 HCHON20002260 8.723 0 HLUNG10000550 11.709 0 PROST20130530
64.069 0 SPLEN20169720 43.864 0 SPLEN20194050 30.978 0
KIDNE20028720 12.368 1.993
[0618] TABLE-US-00053 TABLE 51 CloneID FELNG HLUNG BRACE20096200 0
70.38 BRAWH20004600 0 2.238 BRAWH20030250 0 11.121 BRCAN20006390 0
61.519 BRCAN20280360 0 8.855 BRHIP20238880 0 1.35 CTONG10000940 0
1.428 CTONG20103480 0 6.495 CTONG20129960 0 10.709 CTONG20155180 0
48.707 FCBBF10001210 0 36.439 FEBRA20144170 0 1.98 FEBRA20197110 0
7.756 HHDPC20034390 0 0.933 HLUNG20016330 0 29.367 HLUNG20016770 0
12.888 HLUNG20017120 0 12.093 HLUNG20023340 0 33.714 HLUNG20033780
0 33.957 HLUNG20084390 0 100 IMR3220002430 0 3.147 LIVER20028420 0
14.004 NOVAR20000380 0 2.278 NT2RI20054050 0 2.059 NT2RI20091730 0
4.091 NT2RP70044280 0 12.369 OCBBF20020830 0 40.304 OCBBF20125530 0
4.302 PLACE60004630 0 28.618 PROST20057930 0 14.383 PROST20107820 0
0.892 PROST20185830 0 33.898 PUAEN20030180 0 12.294 SMINT20121220 0
12.822 SPLEN20002220 0 44.799 SPLEN20054290 0 26.875 SPLEN20128000
0 1.253 SPLEN20157300 0 51.319 SPLEN20176200 0 18.8 SPLEN20179180 0
3.344 SPLEN20211940 0 12.373 STOMA20013890 0 21.183 TBAES20000590 0
5.527 TESTI20094230 0 59.311 TESTI20184620 0 10.365 TESTI20334410 0
8.049 THYMU20000570 0 4.974 THYMU20039810 0 1.915 TRACH20007020 0
14.4 TRACH20141240 0 3.786 TRACH20183170 0 10.745 D9OST20033970
61.464 0 FELNG20002410 100 0 HCHON20016650 33.188 0 KIDNE20029800
67.783 0 OCBBF20145760 78.585 0 SPLEN20162680 9.292 0 TESTI20214250
37.027 0 TRACH20005400 30.64 0 HCHON20002260 8.672 2.958
HLUNG10000550 11.642 3.971 NT2RI20023910 34.882 8.923 SPLEN20008740
10.483 1.788
[0619] TABLE-US-00054 TABLE 52 Alteration of the expression level
of each clone due to TNF-.alpha. stimulation to human monocyte cell
line THP-1 and alteration of the expression level of each clone due
to co- culture of gastric cancer cell line MKN45 with Helicobacter
pylori. ctl, TNF_1 h, and TNF_3 h in the column of THP-1,
respectively, indicate the relative mRNA expression levels in
unstimulated THP-1, in the cell stimulated with 10 ng/mL
TNF-.alpha. for 1 hour, and in the cell stimulated with 10 ng/mL
TNF-.alpha. for 3 hours; ctl, Hp, and .DELTA.cagE in the column of
MKN45 indicate the relative mRNA expression levels in MKN45
cultured without Helicobacter pylori, in the cells co-cultured with
cag PAI- positive Helicobacter pylori (TN2) (at a ratio of
MKN45:TN2 = 1:100 cells (colonies)) for 3 hours, and in the cells
co- cultured with the cagE mutant (TN2.DELTA.cagE) (at a ratio of
MKN45:TN2.DELTA.cagE = 1:100 cells (colonies)) for 3 hours,
respectively. [ATAC-PCR] THP-1 Clone TNF_1 TNF_3 MKN45 Name ctl h h
ctl Hp .DELTA.cagE 3NB6920014080 4 4 4.1 ADRGL20013010 0.1 0.1 0.1
0.04 0.04 0.04 ADRGL20067670 0 2.6 0 ADRGL20083310 0.3 0.3 0.3
ASTRO20032120 1.4 1.7 0.6 1.2 0 1 ASTRO20084250 1.2 1.1 0.4 0.1
0.04 0.1 ASTRO20152140 0.1 0.9 0.4 1.6 1.8 1.6 ASTRO20166810 0.7
0.7 0.2 4.3 3.5 4.4 ASTRO20181690 1.5 1.9 0.2 1.8 2.2 0.2
BLADE20004630 3.3 2.9 2.2 0.3 0.8 0 BRACE20006400 3.6 3.5 3.6
BRACE20019540 0.7 0 0 BRACE20038480 0.5 0.6 0.3 0.2 0.2 0.2
BRACE20039040 2.5 2.2 2.3 0.1 0.7 1.1 BRACE20039440 0.3 0.3 0.2
BRACE20052160 2.7 2.3 1.9 1.3 0.8 1 BRACE20053630 0.2 0.2 0 3.4 3
2.6 BRACE20057620 0 3.7 0.5 0 0 0.3 BRACE20058810 3.8 2 2.8 0.6 0
0.9 BRACE20060720 0 1.3 0 0 0 0.04 BRACE20060840 2.2 1.7 1.6 3.9
3.8 1.6 BRACE20061740 1.9 2.1 2.7 BRACE20062640 1.9 0.2 2.4 2.3 1.2
1 BRACE20063780 0 0.1 0 0.4 0.2 0.2 BRACE20067430 2.4 0 1.7 0.04 0
0 BRACE20090440 1.1 1.8 2.2 1 0.5 1.3 BRACE20101700 3.1 1.8 1.7 0.5
0.4 1 BRACE20114780 1 1.5 0.6 1.2 0.4 0.2 BRACE20151320 0 0 0.1 0.1
0.2 0 BRACE20152870 0.6 1.3 1.5 0.4 0.3 0.3 BRACE20163150 1.5 1.7
0.9 1.4 1.4 1.7 BRACE20165830 2.6 4.9 3.3 BRACE20201570 0 0 0 0 0 0
BRACE20210140 1.7 1.4 1 1 0.6 0.5 BRACE20223330 0.1 0 0 0 0.1 0
BRACE20224500 0.2 0 0.2 0 0 0.1 BRACE20229280 0.2 0.04 0.4 0 2.1 0
BRACE20235400 1.8 0.6 1 0.3 0.6 0.1 BRACE20266750 1.8 2.1 1 1.3 1.1
0.9 BRACE20267250 0.8 0.8 0 BRACE20269710 0.9 0.9 0.7 0.4 0.2 0.1
BRALZ20018340 1.1 1 0.5 0.3 0.4 0 BRALZ20058880 1 3.1 2.5
BRALZ20059500 1.7 1.5 2.3 BRALZ20064740 1.9 2.8 1.2 8.9 0 0
BRALZ20069760 1.3 0.4 0 0.04 0.04 0.04 BRALZ20075450 1.3 0 0 0.04
0.04 0.04 BRALZ20088690 1.8 1.4 1.5 0 0 1.6 BRAMY20002770 0.8 2.4
0.3 1.2 0 0 BRAMY20004110 0.8 0 0 BRAMY20060920 0.3 11.8 12.2
BRAMY20103570 0 0.1 0.1 0.6 0 0 BRAMY20144620 0.7 0 0.9
BRAMY20152110 1.8 1.7 1.2 2.5 2.3 0.8 BRAMY20162510 0.1 0 0 0.7 0.7
0 BRAMY20163250 3.4 4.2 2.4 2.2 1.5 0.9 BRAMY20163270 3.8 0.7 4.5
BRAMY20168920 2.4 2.5 2.2 0.2 0.04 0.1 BRAMY20178640 1.7 1.6 1.9
0.9 1 0.5 BRAMY20184670 0.4 0.3 0.2 0.04 0.2 0.6 BRAMY20204450 3.6
3.6 1.6 0 0 0 BRAMY20210400 0.5 0.5 0.5 1 0.2 0.9 BRAMY20215230 1
0.7 1.1 1.9 0.8 1 BRAMY20218670 1.6 0 1.5 0.2 2.6 0.1 BRAMY20229800
5 3.9 0.5 1.4 4 1 BRAMY20229840 0.04 0 0.04 0.3 0 0.2 BRAMY20231720
1.1 1.3 1.6 BRAMY20247280 3.5 2.2 1.9 2 0.7 0.5 BRAMY20261680 5.2 4
3 3.5 3.2 2.5 BRAMY20266850 0.4 4.4 6.9 2.2 2.9 2.7 BRAMY20267130
13.7 0 0 BRAMY20277140 3.3 2.5 3 0.7 0.8 0 BRAMY20280720 0 9.8 1.1
BRAWH10000930 2.6 1.3 1.9 0 0 0 BRAWH20015350 0 0 0 BRAWH20017010
0.9 0 0 0.6 0.2 0.9 BRAWH20029630 1.9 2.4 1.8 1.4 0.2 0.04
BRAWH20100690 3.2 0.9 0.8 BRAWH20106180 0 2.7 0.5 BRAWH20107540 2.1
1.3 0.8 1.1 1.1 0.6 BRAWH20110660 1.7 2.1 2.4 1.4 1.4 0.9
BRAWH20118230 0 0 0.04 2.3 0.9 1.9 BRAWH20122770 0 0 0.8
BRAWH20126190 0 0 0 0 0 0 BRAWH20132190 2.2 2.2 1 1.8 1.5 0.4
BRAWH20138660 3.3 2.2 2.1 BRAWH20139410 0.9 1.7 0.2 2.1 1.9 0.7
BRAWH20155950 1.5 1.8 1.5 0.9 0 0 BRAWH20158530 58.9 19.3 41.1
BRCAN20060190 0.2 0 0.2 BRCAN20147880 0.3 0.3 0 0.5 1 1.3
BRCAN20273340 2.8 3.5 0 0.3 0.3 0.3 BRCAN20273640 0.3 0.4 0.2 0.7
0.8 0.3 BRCAN20275130 3.9 3.6 2.3 0.2 0 0 BRCAN20280210 0 0 0 0.8 0
0 BRCAN20280400 3 3.6 2.6 1.8 1.7 1 BRCOC20021550 0.7 0 0.2 0.3 0.3
0 BRCOC20037400 1.5 1 1.2 0.1 0 0.2 BRCOC20105100 3.8 1 1.5
BRHIP10001740 0.8 0.7 0.9 0.4 0 0 BRHIP20001630 0.5 0 0
BRHIP20096170 0 0.4 0.3 BRHIP20103090 1 1 1.3 0.9 0 0.7
BRHIP20105710 1.5 0 1.9 0.7 0.7 0.9 BRHIP20110800 1.9 2.7 2.2 0.8 0
0 BRHIP20111200 0.3 0.9 1.1 BRHIP20118910 0 0 0 BRHIP20129720 0 0.1
0 0 0 0 BRHIP20143860 6.2 5.3 6.7 3.6 2.7 2.4 BRHIP20173150 0 0.04
0 0.9 1.6 2.8 BRHIP20175420 2.4 2.4 2.5 0.6 0 0 BRHIP20186120 1.2
2.9 0 BRHIP20194940 0.04 0.7 0.3 BRHIP20196410 1.7 2.6 1.8 0.9 2 1
BRHIP20207430 0 0 0.2 0 0 0.1 BRHIP20218580 1.1 1.8 0.9 1.2 0.6 0.3
BRHIP20233090 2.8 1.5 1.8 0.5 0 0.4 BRHIP20284800 2.3 1.5 1.7
BRHIP30004880 0.04 0.2 0.04 BRSSN20046570 2.5 2 1.7 2.6 1 1.2
BRSSN20142940 0 0 0.04 1.2 1.3 1.2 BRSSN20152380 0.5 1 0.7 0.04
0.04 0.04 BRSSN20176820 1.2 0.5 0.04 1.5 1 1.4 BRSSN20187310 2.5
9.6 27.6 BRTHA20046390 2 2.1 2 3.2 3.2 2.4 CD34C30004240 1 1.3 1.8
2 1.7 1.3 CD34C30004940 0 2.9 0 COLON20043180 7.2 6.6 7.2
CTONG10000620 0.04 0.04 0.04 CTONG20014280 0.4 0.5 0 CTONG20095270
0 1.9 1.6 0 0 0 CTONG20095290 1.5 0.5 0.8 0 0 0 CTONG20096750 0 0.1
0 0 0 0 CTONG20100240 0.2 0.8 0.04 0.2 0.04 0.04 CTONG20103480 2.7
2.9 3.7 0 0.1 0 CTONG20105660 7.2 4.3 3.7 3.1 2.8 3.1 CTONG20121010
0 0 0 1.7 1.6 0 CTONG20128470 0.8 1 1 0.2 0.3 0.2 CTONG20138030 2.7
2.1 1.9 2.2 0.8 1.8 CTONG20139070 2.4 2.3 2.2 0.9 0.4 1.1
CTONG20146970 7 6.9 5.4 7.3 2.7 6.8 CTONG20158150 0.2 3 0.4 1.6 0 1
CTONG20186320 3.6 2.5 3.8 1.8 1.8 0.6 CTONG20265130 1.2 2.2 6.3 0.8
6 20.3 D3OST20006540 0.7 1.7 0.4 0.7 0.2 0.9 D3OST20037970 2.7 2.7
1.7 1.9 0.6 1.3 D9OST20031370 0.8 2.9 1.1 0.04 0.04 0.04
DFNES10001850 0 0 0 DFNES20031920 2.1 2.2 0.8 1.2 2.9 0.8
FCBBF10005060 0.9 0 1 FCBBF20032970 3.1 3.6 3.6 1.6 0.9 2
FCBBF20035280 0 0 0 FCBBF20054280 2 2 2.4 FCBBF20071860 0.9 1.1 1.9
0 0 0.04 FCBBF30001840 1 1.6 1.5 2.5 0 0 FCBBF30016320 1 1.9 0.6
1.3 1.5 0.3 FCBBF30016570 2.4 1.8 1.7 0.4 0.2 0.4 FCBBF30033050 4.1
0 3.2 1 0 0.3 FCBBF30071520 2 0 1.2 FCBBF30083820 2.9 3.5 1.4 2.2
1.6 0.5 FCBBF30215060 0.5 0.5 0.5 FCBBF30251420 0 2.6 0 0.3 0.1 0.6
FCBBF30252520 1 3.8 2.4 0.4 0 0 FCBBF30262360 0.0 0.04 0.04
FCBBF30266920 0.3 0.4 2 FCBBF30278630 1.3 3.6 0 FCBBF30285280 0 0 0
0 0 0 FCBBF40001420 0.3 0.7 0.3 0.1 0.7 0.1 FEBRA10001880 0.5 0.4
0.4 0.4 0.4 0.5 FEBRA20010120 4.2 6.4 3.5 0.7 0 0 FEBRA20017050 0
0.8 0.8 0.04 0 0 FEBRA20034360 0.8 0.9 0.7 0.1 0.1 0.1
FEBRA20037260 1.2 1.4 0.9 FEBRA20037500 0.04 0 0.1 4.4 4 3.4
FEBRA20082100 0.2 0.3 0.5 2.1 0.7 0.5 FEBRA20095880 0.9 0 0.5 0.7
0.3 0.7 FEBRA20167390 0.3 0 0 0.9 0.3 0.6 FEBRA20176800 0.9 0 0
0.04 0 0 FEBRA20226010 0.9 0.2 0.2 0 0 0 HCASM10000500 2.7 2.7 3.1
0.9 0.8 0.4 HCHON20002260 0.1 0 0 0.8 0.6 0.9 HCHON20008980 1.8 2.4
0.2 HCHON20009350 0 0 0 HCHON20010990 0.3 0.3 0.3 HCHON20011160
0.04 0.2 0.04 HCHON20015230 2.6 2.3 2.4 1.2 1.7 0.6 HCHON20022470 2
1.2 0.7 1.6 1.1 1.1 HCHON20035130 1.9 2 2.4 1.3 0 2 HCHON20043590
2.6 2.4 1.8 1.5 0.3 0.6 HCHON20067220 1.5 2.1 2.3 2.1 0 0.9
HCHON20076500 2.1 2.4 2.1 0 0.1 0 HEART20021840 0.6 0.4 0
HEART20067870 0 0 0 0 0 0 HEART20083640 0.8 0.2 0.2 HHDPC10000650
1.4 1.4 1.1 0.7 0.4 0.3 HHDPC20034390 1.1 0.5 1.2 0.3 0.04 0.04
HHDPC20095280 0.8 0.7 0.5 0 0.5 0 HLUNG10000550 7.6 7 6.9 2.1 1.4 1
KIDNE20018970 1.5 1.2 0.9 1.4 0.9 0.9 KIDNE20028720 1.5 1.2 0
KIDNE20079440 1.4 1.8 0 KIDNE20096470 2.1 2.6 2.3 1.3 1 0.7
KIDNE20106740 0.2 0.1 0 0 0 0 KIDNE20120090 0.2 0 0 KIDNE20127750
1.9 0.6 0.4 KIDNE20130450 0.9 0.9 1.3 0.1 0.8 0.4 KIDNE20132180 0.7
0 0 KIDNE20141190 0.1 0.2 0 0.4 0.3 0 KIDNE20148900 4.6 0 4.7
KIDNE20163880 0.6 1.5 0 2.2 1.8 1.2 KIDNE20182690 0.5 0.4 3.9 2.5
3.1 3.1 LIVER10004790 1.5 3.3 1.6 0 0 0 LIVER20011130 2.4 0.8 0 0.2
1.9 0.2 LIVER20038540 0 5.1 0 1.2 4.9 0 LIVER20055440 0.5 0.5 0.4
0.3 0.1 0.1 LIVER20062510 1 1.1 1.2 0 0 0.9 LIVER20085800 0 0.8 0.5
MAMGL10000830 5.4 4.3 0.1 0.6 0.6 0.7 MESAN20031900 0.7 0.3 0.4 0.1
0.1 0.1 MESAN20121130 2.6 2.8 2.2 0.1 0.04 0.04 MESAN20127350 1.6
0.7 0.3 MESAN20130220 0.9 2.3 2.2 MESAN20154010 2.6 2.2 2 2.9 2.4
2.5 MESAN20174170 0 0 0.7 0 0 0
NOVAR10001020 0.3 0.04 0.04 NT2NE20053580 0.8 0 0 NT2NE20089610 0.9
1.3 1.5 0.1 0.04 0.04 NT2NE20089970 0.7 0 0 0 0 0 NT2NE20146810 2.8
2.3 1.9 NT2NE20155110 2.5 2.6 2.9 NT2NE20156260 1.3 1.3 1.7 0.3 0.1
1 NT2NE20158600 0.8 3.4 3 NT2NE20172590 0 0.8 0 NT2NE20174920 1.8 1
1.1 1.4 0 0 NT2NE20181650 1 1.1 0.5 0.2 0.1 0.04 NT2RI20005750 0
0.4 0 0.6 0.04 0.8 NT2RI20009870 3 2.3 2.3 7.3 2.1 3.4
NT2RI20023160 3.5 1.1 2.8 1.7 0.4 1.8 NT2RI20040930 0.7 0.6 0.5 0.3
0.1 0.1 NT2RI20046080 1.8 1.8 1.5 1.2 0.8 0.9 NT2RI20055790 0.9 0.9
0.9 0.8 0.6 1 NT2RI20069730 2.4 2.1 1.7 2.1 1.4 1.4 NT2RI20203900 0
0 0 0 0 0 NT2RP70062230 1.8 0 1.5 NT2RP70102350 1.7 0.04 0.04
NT2RP70110860 0 0 0.6 0 0 0 NT2RP70111320 3.2 4.4 2.8 NT2RP70130020
0 0 0 1 0 0.1 NT2RP70143480 1.2 2 1.7 0.8 1.1 0.6 NT2RP70150800 0.8
0.3 0.3 NT2RP70157890 4.6 1.1 0.3 2.2 1.8 0 NT2RP70169110 0.5 1.3
1.7 1 3.3 2.5 NT2RP70175670 0.3 0.1 1.4 4.3 3.3 3.3 NT2RP70188020
2.5 2.8 2.6 0 0 0 NT2RP70188710 0 0.1 0.2 4.3 2.8 2.9 NT2RP70190640
0.4 0.4 0.9 NTONG20029480 3.1 0.7 2.2 NTONG20064840 1.5 1 1
NTONG20067090 2.5 2.1 2.3 0.4 0.1 0.2 NTONG20070340 0.1 0 0 6.3 1.3
0.7 NTONG20077560 0.5 0.5 0.5 NTONG20083650 2.9 2.9 2.7 2.5 2.5 1.9
NTONG20090680 2.1 2 2.4 2 1.3 1.6 OCBBF20005230 1.7 1.3 2.3 0.9 0.7
0.7 OCBBF20019380 0.6 0.6 0.5 0 0 0 OCBBF20020150 4.2 3.2 3 1 0 0.6
OCBBF20020830 2.7 2.7 1.3 4.4 2.3 2.1 OCBBF20039250 1 1.2 0.9 0.4
0.1 0.5 OCBBF20041680 1.4 0 0 OCBBF20047570 0.04 0 0 0.3 0.2 0.6
OCBBF20051610 0 0.04 0.04 0 0 0 OCBBF20054200 0.4 0.3 0 0.04 0.04
0.04 OCBBF20061720 1.3 2 0.2 0.7 1.2 0 OCBBF20062140 3.3 3.1 5
OCBBF20071960 0.1 0 0 OCBBF20072320 0.04 0 0.04 0.04 0.04 0.04
OCBBF20079310 0.04 0 0 0 0.04 1 OCBBF20081380 6.3 6.1 5.1 0.8 0.4
0.6 OCBBF20085200 0.1 0.5 1.3 OCBBF20094240 0.9 1.5 1.6 1.1 0.3 0
OCBBF20107920 2.9 2.9 2.6 2.6 0.7 0.3 OCBBF20127040 1.4 1.3 0.5 0.2
0.04 0 OCBBF20130110 3.2 2.4 1.8 OCBBF20139260 2.1 0.7 0.2
OCBBF20164050 0.3 0.3 0.2 0.2 0 0.04 OCBBF20178990 2.1 0.7 0.2 0.9
0 0 OCBBF20180840 3.7 2.7 3.1 0.1 0.3 0.3 PEBLM10000240 2.1 2.2 1.6
0 0.3 0 PEBLM20013120 3.3 0.5 3 PEBLM20024550 0.1 0 0 3 2.2 0.7
PEBLM20052820 1.9 2.1 2.2 1 0.6 0.8 PEBLM20074370 0.9 0.9 1.7 3.7
3.1 3 PERIC20002140 0.04 0.9 0.4 0.7 0.3 0.8 PERIC20004780 0 0.04
0.1 0.04 0 0.04 PLACE60003480 4.1 1.5 4.8 0.6 1.6 5.1 PLACE60136720
0.5 0.7 0.7 0.6 0.7 0.2 PLACE60155130 0.7 2.3 0 PLACE60169420 1.2
1.4 1.6 0.6 0 0.8 PLACE60181070 42.3 10 28.2 PROST10004800 3.1 3.2
1.8 PROST20120160 0 0.6 0 0 0.3 0.9 PROST20144220 2.5 2.8 2.4 1.6
0.5 0.2 PROST20149160 0.7 0 0.4 1.6 0.6 0.6 PROST20149250 0 0.9 0.4
0 0 0 PROST20151240 1.3 0.7 0 0 1.2 0 PROST20153320 1.4 1.2 1.8 1.4
0.3 1.2 PROST20161950 0 0 0.6 2.2 1.4 1.2 PROST20189770 1.1 1.4 0.8
2.8 2.8 2.1 PUAEN20003740 3.1 0.5 2.8 1.4 0.5 2.4 PUAEN20011880 1.3
2.4 0.4 0.1 0.3 0 PUAEN20015260 0.04 0.04 7.4 PUAEN20025680 1.9 1
2.3 3.1 0.9 1.1 PUAEN20040670 0.3 0.5 0.2 1.3 0.5 1 PUAEN20045250
1.8 1.6 1.6 1.9 1.6 1.1 PUAEN20078980 1.1 0.3 0.7 0.5 0 0.1
PUAEN20085150 2 1 2.3 1.6 1.1 0.2 SKMUS20018230 1.9 2.2 1.8 0.8 0.5
0.6 SKMUS20028210 1.6 2.7 2.2 0 0 1.3 SKMUS20031680 0.9 0 0 1.2 2.4
0.3 SKMUS20046670 0.3 0.3 0.3 SKNSH20062340 0.6 0.5 0 SKNSH20080430
1.1 2.6 0.5 0 1.3 0 SMINT20001760 1.8 1.5 0.7 0.3 0.1 0.3
SMINT20013480 1.3 2.1 0.9 SMINT20014580 2.7 2.1 1.4 1.2 0 0.6
SMINT20033400 2.6 1.7 1.4 SMINT20047810 2.2 0.7 0.5 SMINT20051610
0.1 0.1 0.3 0.4 0.1 0.5 SMINT20056210 0.9 1.8 0 SMINT20060780 0.2
0.6 0.5 0.04 0.04 0.04 SMINT20080540 0 0 0 SMINT20105000 0 1.1 0.3
SMINT20108530 1.3 1.5 0 0.04 0.04 0.04 SMINT20122850 0.04 0.04 0.04
0.04 0.04 0.04 SMINT20122910 0.3 0.3 0.3 SMINT20153530 4.8 4.6 5.6
2.7 1.5 1.8 SMINT20161220 8.5 6.2 19.5 2 1.1 1 SMINT20163960 0.6
0.5 1.4 0 0 0 SMINT20164770 2.4 2.1 1.6 1.8 1.2 1 SMINT20168570 0 0
0 SPLEN20008820 2.5 2.3 2.7 1.6 1.3 0.8 SPLEN20011410 0.4 0.4 0.1
SPLEN20013540 1.6 0.9 1.1 2.4 1.4 1.8 SPLEN20019450 1 1.8 1.2 0.2
0.6 0.4 SPLEN20022230 4.5 6.2 3.9 1.4 1.1 1.6 SPLEN20040600 3.2 4.5
3.6 0 0 0 SPLEN20076530 0.04 0.04 0.04 0 0 0 SPLEN20101190 0.3 0.2
0.6 1.6 0 0 SPLEN20126190 2.5 3.4 2.8 5.2 3.5 3.1 SPLEN20152760 4.2
3 3.2 1.2 0.8 1.6 SPLEN20157300 0.4 0.5 2.5 SPLEN20158990 1.9 0.9
2.6 1.1 1.1 1.3 SPLEN20163560 0.3 0.6 0.3 0 0 0 SPLEN20174260 0.4 0
0 0.3 0.1 0.1 SPLEN20211570 2.3 2.3 2.2 1 2.1 1.4 SPLEN20214580
0.04 0.6 0.9 1.4 1.3 2.6 SPLEN20245300 3.1 2.6 1.9 0.6 0 0.2
SPLEN20279950 0.8 2.1 0.3 SPLEN20280660 0.6 0.5 1 0 0 0
SPLEN20283650 1.8 1 0.8 0.8 0 0 SPLEN20329240 0.2 0 0 STOMA20010250
2 0.9 1 0 0 0.7 STOMA20032890 0.9 1.5 0.4 STOMA20048520 0.04 2 0.4
0 0.9 0 STOMA20057820 1.3 1 0 4.3 4.1 0 STOMA20062290 0.4 0.6 0.4
0.3 0.3 0.2 STOMA20076800 1.1 0.7 0.6 1.2 0.6 0.3 TESTI20001170 0 0
0 0.8 0.6 0.7 TESTI20002780 0 0 0 TESTI20004890 1.1 0.7 0.6 0 0.2
0.4 TESTI20011200 6.3 3.7 5.9 0.5 0.04 0.2 TESTI20018230 0 0 0 0.04
0.04 0.04 TESTI20035960 0.1 0 0 0.04 0.04 0.04 TESTI20038270 0 0 0
TESTI20044230 0 0 0 0.6 0.2 0.2 TESTI20046750 0.4 0.04 0.04 1 0.8 0
TESTI20060400 1.2 2 0.2 0.7 0.5 0.04 TESTI20066770 0 0 0 0.04 0.04
0.04 TESTI20076850 0 0.6 0 0.04 0.04 0.04 TESTI20083940 0.9 1.5 1.4
0 1.2 1.3 TESTI20087620 0.8 2.3 0.8 1.1 0.04 0.1 TESTI20098530 5.3
1.2 0 TESTI20105720 2.7 3.5 2.5 0.04 0.1 0.04 TESTI20108720 0.04
1.5 1.1 2.5 2.1 1.8 TESTI20123080 6 0 0 TESTI20128350 1.4 1.6 0
TESTI20136100 3.1 1.9 2.1 TESTI20137670 0.4 0.4 0.4 TESTI20143240
0.2 0.1 0.1 0.3 0.04 0.3 TESTI20143620 0.04 0 0 TESTI20156100 0.1
0.04 0.1 TESTI20161970 1.2 0.7 0 1.1 0.4 1 TESTI20168480 0.5 5.7
0.5 TESTI20168960 0.5 0.5 0.5 TESTI20178160 0.04 0.04 0.04 0.04
0.04 0.04 TESTI20185810 0.9 0 0 TESTI20199170 0.7 0 0 0.9 0.8 0
TESTI20200260 0.3 0 0 TESTI20200710 3.9 2.6 2.4 2.5 3.5 2.9
TESTI20202650 0.04 0.04 0.04 1 1.2 0.3 TESTI20220100 0 5.7 0
TESTI20224620 0 0 1.5 TESTI20229600 0 0 0 TESTI20230850 0.04 0.04 0
0.04 0.04 0.04 TESTI20231920 0.5 0.5 0.5 TESTI20234140 1.8 0.3 0.3
TESTI20234270 2.6 2.8 2.9 0.5 0.04 0.3 TESTI20238000 0.2 0 0.04
0.04 0.04 0.04 TESTI20238610 0.04 0.04 0.04 TESTI20239510 0 0.2 0
0.04 0.2 1 TESTI20242990 1.8 2.1 1.8 0 0 0 TESTI20265250 2.1 1.6
1.9 1.5 0.8 0.4 TESTI20265370 0.04 0.04 0.04 0.04 0.04 0.04
TESTI20266740 0.2 0 0.7 0.04 0.04 0.04 TESTI20272390 1.3 1.2 0.8
0.2 0.2 0.4 TESTI20275030 0 0 0 0 0 0.3 TESTI20275620 1.3 0.04 0.7
TESTI20277360 0 0 0 TESTI20282540 0.04 0 0.1 0.2 0.04 0.3
TESTI20284880 0.4 0.2 0.1 0.04 0 0.1 TESTI20285830 0.04 0.04 0.04
TESTI20288110 1.2 0 0 TESTI20289850 0.04 0 0 0.04 0.04 0.04
TESTI20307540 0.6 0.8 0 TESTI20308600 0.5 1.2 0.5 TESTI20311290 0 0
0 0 0 0.7 TESTI20317600 0 0 0 0.04 0.04 0.04 TESTI20319190 0.2 0 0
0.04 0.04 0.3 TESTI20332420 0.6 0.1 0.9 TESTI20335200 0.9 1.4 0.9
TESTI20342430 0 2.8 0 0.6 0.6 0.5 TESTI20345060 0.1 0 0.04
TESTI20347300 0.9 0.6 1.4 0.04 0 0 TESTI20357960 1 1 1.7 2.7 1.3
1.7 TESTI20361140 0.04 0.04 0.04 0.2 0 0 TESTI20369220 0.04 0.04
0.04 TESTI20369690 1.5 0 1.3 1.3 1.4 1 TESTI20370020 0.4 1.7 0.1
TESTI20371030 1.3 1.3 1 0.8 0.5 0.5 TESTI20386230 2 0.2 0.3
TESTI20391210 0.6 2.3 4.9 3.1 0 2.4 TESTI20392090 0 0 0.04 0.04
0.04 0.7 TESTI20392250 9.3 7.8 3.8 TESTI20392270 1.8 1.4 1.6 1.1
1.6 1.1 TESTI20401020 0.2 0.5 0.8 0 0 0 TESTI20401430 4.3 4.8 4.3
TESTI20409440 1.4 0.5 0.3 0.5 0 0.3 TESTI20415640 0.8 2.5 1 0 0 0
TESTI20424000 0.2 0.04 0.04 0 0 0 TESTI20424730 1.8 0.7 2.9 3.8 0
3.3 TESTI20425070 2.3 2.4 2.6 1.9 1.4 1.2 TESTI20433130 0 0 0
TESTI20438570 0.8 0.6 0.6 0.8 0.6 1.2 TESTI20443090 0.1 0.1 0.1 0.3
0.5 0.6 TESTI20463520 0 0 0 TESTI20465520 0.6 0.6 0.5 0.2 0 0.1
TESTI20478010 0.9 1.7 0.7 0 0.3 0 TESTI20478180 0.04 0.04 0.04 0.04
0 0 THYMU20029100 1.9 1.2 2.3 2 2.9 2.5 THYMU20061700 0 0 0 0.7 0.2
0.2 THYMU20095960 2.9 2.4 0.5 THYMU20111180 1.1 0.6 0.5 0 0 0
THYMU20118060 0.2 0 0.2 0.04 0.04 0.04 THYMU20130890 0.6 1.3 3.3
THYMU20142040 1 1.1 0.7 1.3 1.1 1 THYMU20142970 4 3.5 3.8 1.6 2 0.6
THYMU20153160 1 0.7 1 0.1 0.1 0.04 THYMU20158250 10.4 7 5.5 1.1 0 0
THYMU20187720 3.2 3.2 2.8 2.4 2.2 2.3 THYMU20194360 1.8 2.1 1.7 0.4
0.3 1.3 THYMU20208300 1.9 1.9 1.6 0.3 0.2 0.3 THYMU20226600 3 0 1.4
1.1 0.3 2.6 THYMU20239000 2.1 2.3 2.8 1.4 0.8 1.1 THYMU20253250 1.1
0.3 0.3 THYMU20272490 2.7 1.4 0.6 0.04 0.04 0.04
THYMU20284120 3.8 4.1 4 0.4 0.04 0.5 THYMU20286290 0 2.1 0.4 3.1
2.5 1.7 TKIDN10000010 2.2 2.2 2.5 1.2 1 1.1 TRACH20005020 0 0 0 2.8
0.9 0.5 TRACH20032720 0.1 0 0 0.6 0.04 0.1 TRACH20041830 0.8 0.2
0.9 TRACH20060150 0.2 0.9 2 TRACH20076760 5.1 4.9 4.5 0.6 0.5 0.4
TRACH20082780 0 0 0 TRACH20091230 0.4 0 0.2 2.1 1.1 1.2
TRACH20099340 1.8 3.8 4.9 1.9 2.5 0.9 TRACH20109650 3.5 3.3 3.5 3.7
3.7 3.4 TRACH20115740 0.04 0.04 0.04 TRACH20134950 5.6 5 4 3.5 1.2
1.9 TRACH20135520 1 0.9 0.6 0.9 0.9 0.5 TRACH20153810 2.1 0 0
TRACH20184490 2.2 3.2 2.8 1.6 0 0 TSTOM20001390 1.5 2.1 1.8 2.5 0.4
2.5 TSTOM20005690 1.3 0.8 1.1 0.3 0 0.1 UMVEN10001560 2.4 2.6 3.3
0.6 0 0.04 UMVEN20003540 5.2 3.9 4.9 3.1 2.4 2.8 UTERU20004240 0.04
0.2 0.1 0.04 0 0.04 UTERU20046980 0 0 0 UTERU20055930 2.5 3.6 2.9
2.3 1.6 2.5 UTERU20068990 0.04 1.3 0.04 0.1 0 0 UTERU20070810 2.7
1.9 2.4 1.9 1.3 1.1 UTERU20115740 3.1 3.2 5 2.3 1.9 0 UTERU20119060
0.8 1.9 0 1.9 0.3 1.6 UTERU20124070 2 2.7 1.8 2.8 2.1 1.8
UTERU20126880 0 2.2 0.1 UTERU20134910 2.5 2.7 2.3 2.9 1.4 1.3
UTERU20146680 0 0.1 0 0.5 0 0.04 UTERU20176130 2.9 1.3 1.6 1.9 0.6
0.8 UTERU20185230 3.1 3.2 1.8 1.6 1.1 0.6 UTERU20186740 1.9 1.4 0.7
0.04 0 0
Homology Search Result Data
[0620] Data obtained by the homology search for full-length
nucleotide sequences and deduced amino acid sequences.
[0621] In the result of the search shown below, both units, aa and
bp, are used as length units for the sequences to be compared.
[0622] Each data includes Clone name, Definition in hit data, P
value, Length of sequence to be compared, Homology, and Accession
number (No.) of hit data. These items are shown in this order and
separated by a double-slash mark, //.
3NB6910001910//ALANYL-TRNA SYNTHETASE (EC 6.1.1.7) (ALANINE--TRNA
LIGASE) (ALARS).//3.10E-20//392aa//24%//067323
3NB6920014080
3NB6920014590//HOMEOBOX PROTEIN
DLX-6.//1.00E-91//226aa//78%//Q98877
ADIPS10000640//Homo sapiens synaptic glycoprotein SC2 (SC2) mRNA,
complete cds.//1.60E-169//303aa//100%//AF222742
ADIPS20004250//ZINC FINGER PROTEIN
OZF.//6.60E-27//223aa//32%//Q15072
ADRGL10001470//CYTOCHROME P450 11B1 PRECURSOR (EC 1.14.15.4)
(CYPXIB1) (P450C11) (STEROID
11-BETA-HYDROXYLASE).//1.60E-38//84aa//98%//P15538
ADRGL20000640
ADRGL20011190//spectrin, beta, non-erythrocytic 1 [Homo
sapiens].//1.00E-36//250aa//38%//NP.sub.--003119
ADRGL20012870
ADRGL20013010
ADRGL20013520
ADRGL20018300//KINESIN LIGHT CHAIN
(KLC).//1.20E-207//566aa//70%//Q07866
ADRGL20018540
ADRGL20028570//Rattus norvegicus MG87 mRNA, complete
cds.//2.90E-69//250aa//53%//AF095741
ADRGL20035850//CYTOCHROME P450 17 (EC 1.14.99.9) (CYPXVII)
(P450-C17) (STEROID 17-ALPHA-HYDROXYLASE/17,20
LYASE).//7.30E-52//99aa//100%//P05093
ADRGL20044590
ADRGL20048330//Mus musculus mRNA for granuphilin-a, complete
cds.//0//673aa//89%//AB025258
ADRGL20061930//transposon-derived Buster1 transposase-like
protein//6.00E-65//500aa//33%//NP.sub.--067034
ADRGL20067670
ADRGL20068170
ADRGL20068460
ADRGL20073570
ADRGL20076360
ADRGL20078100//NADPH:ADRENODOXIN OXIDOREDUCTASE PRECURSOR (EC
1.18.1.2) (ADRENODOXIN REDUCTASE) (FERREDOXIN-NADP(+)
REDUCTASE).//3.10E-147//276aa//99%//P22570
ADRGL20083310
ASTRO10001650//DREBRIN E.//4.80E-293//540aa//99%//Q16643
ASTRO20001410
ASTRO20005330
ASTRO20008010//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)
(HTF1).//6.00E-57//143aa//70%//Q03923
ASTRO20012490
ASTRO20027430//RAS SUPPRESSOR PROTEIN 1 (RSU-1) (RSP-1 PROTEIN)
(RSP-1).//2.20E-18//178aa//34%//Q15404
ASTRO20032120
ASTRO20033160//BRAIN MITOCHONDRIAL CARRIER
PROTEIN-1.//2.70E-125//291aa//80%//095258
ASTRO20055750//Human elastin gene, exon
1.//2.70E-293//654aa//88%//M17282
ASTRO20058630
ASTRO20064750//Homo sapiens BM-003 mRNA, complete
cds.//6.10E-69//214aa//64%//AF208845
ASTRO20072210//PERIAXIN.//2.10E-25//87aa//56%//Q63425
ASTRO20084250//Ciona savignyi mRNA for PEM-3, complete
cds.//3.50E-56//154aa//64%//AB001769
ASTRO20100720
ASTRO20105820//ACTIN INTERACTING PROTEIN
2.//2.60E-111//392aa//56%//P46681
ASTRO20106150//H. sapiens mRNA for calpain-like
protease.//1.80E-291//473aa//98%//Y10552
ASTRO20108190//TUBERIN (TUBEROUS SCLEROSIS 2
PROTEIN).//5.30E-278//513aa//100%//P49815
ASTRO20111490
ASTRO20114370//Mus musculus SMAR1 mRNA, complete
cds.//1.30E-213//461aa//89%//AF235503
ASTRO20114610
ASTRO20125520//dnaj protein [Schizosaccharomyces
pombe]//7.80E-37//260aa//38%//CAB59885
ASTRO20130500//UBIQUITIN-ACTIVATING ENZYME
E1.//2.70E-157//815aa//42%//Q29504
ASTRO20136710
ASTRO20138020
ASTRO20141350//Mus musculus mRNA for granuphilin-b, complete
cds.//7.40E-12//169aa//30%//AB025259
ASTRO20143630
ASTRO20145760//TUBULIN--TYROSINE LIGASE (EC 6.3.2.25)
(TTL).//1.60E-14//233aa//27%//P38584
ASTRO20152140
ASTRO20155290
ASTRO20166810
ASTRO20168470//ZINC FINGER PROTEIN
135.//4.80E-103//289aa//59%//P52742
ASTRO20173480
ASTRO20181690//oocyte-specific protein
P100//1.60E-70//554aa//36%//S23468
ASTRO20190390
BEAST20004540
BGGI110000240
BGGI110001930
BGGI120006160//isomerase-like protein [Arabidopsis
thaliana].//1.00E-52//187aa//47%//BAB00076
BLADE20003400//ZINC FINGER PROTEIN
177.//2.50E-33//205aa//38%//Q13360
BLADE20003890//ZINC FINGER PROTEIN
135.//1.50E-264//471aa//95%//P52742
BLADE20004630
BNGH420088500
BRACE20003070//Rattus norvegicus neurabin mRNA, complete
cds.//2.30E-40//172aa//46%//U72994
BRACE20006400
BRACE20011070//Mus musculus F-box protein FBX15 mRNA, partial
cds.//9.60E-142//471aa//56%//AF176530
BRACE20019540
BRACE20027620//CYTOSOLIC ACYL COENZYME A THIOESTER HYDROLASE,
INDUCIBLE (EC 3.1.2.2) (LONG CHAIN ACYL-COA THIOESTER HYDROLASE)
(LONG CHAIN ACYL-COA HYDROLASE) (CTE-I) (LACH2)
(ACH2).//2.70E-148//423aa//65%//088267
BRACE20037660
BRACE20038000//MAP kinase phosphatase [Drosophila
melanogaster].//3.80E-83//426aa//42%//BAA89534
BRACE20038470//Rattus norvegicus neurexophilin 4 (Nph4) mRNA,
complete cds.//1.70E-57//109aa//98%//AF042714
BRACE20038480//Human SEC14L mRNA, complete
cds.//2.60E-93//179aa//99%//D67029
BRACE20038850
BRACE20039040
BRACE20039440//Drosophila melanogaster CHARYBDE (charybde) mRNA,
complete cds.//6.50E-17//142aa//35%//AF221109
BRACE20039540//MHC class I chain-related gene A protein [Homo
sapiens]//2.00E-116//246aa//90%//NP.sub.--000238
BRACE20050900
BRACE20051380
BRACE20051690
BRACE20052160//Xenopus laevis bicaudal-C (Bic-C) mRNA, complete
cds.//2.10E-13//208aa//30%//AF224746
BRACE20053280//Mus musculus Pdz-containing protein (Pdzx) mRNA,
complete cds.//5.20E-63//223aa//64%//AF229645
BRACE20053480//Mus musculus erythroblast macrophage protein EMP
mRNA, complete cds.//1.70E-133//145aa//97%//AF263247
BRACE20053630//BRITTLE-1 PROTEIN
PRECURSOR.//1.20E-24//208aa//31%//P29518
BRACE20054500
BRACE20055180
BRACE20056810
BRACE20057190//NUCLEOPLASMIN.//5.20E-42//215aa//45%//PO5221
BRACE20057420
BRACE20057620//EUKARYOTIC TRANSLATION INITIATION FACTOR 4E (EIF-4E)
(EIF4E) (MRNA CAP-BINDING PROTEIN) (EIF-4F 25 KDA
SUBUNIT).//1.00E-22//60aa//73%//P48597
BRACE20057730//toxin sensitivity protein KTI12
homolog//1.10E-10//173aa//26%//A64492
BRACE20058580//Homo sapiens HCMOGT-1 mRNA for sperm antigen,
complete cds.//2.10E-178//358aa//96%//AB041533
BRACE20058810
BRACE20059370//PROTEIN 4.1 (BAND 4.1)
(P4.1).//6.70E-52//400aa//32%//P11171
BRACE20060550//ANKYRIN HOMOLOG
PRECURSOR.//1.30E-14//139aa//44%//Q06527
BRACE20060720
BRACE20060840
BRACE20060890//ZINC FINGER PROTEIN ZIC4 (ZINC FINGER PROTEIN OF THE
CEREBELLUM 4).//4.00E-131//264aa//87%//Q61467
BRACE20061050
BRACE20061740
BRACE20062400
BRACE20062640//HYPOTHETICAL 93.7 KDA PROTEIN F48E8.6 IN CHROMOSOME
III.//9.10E-90//343aa//45%//Q09568
BRACE20062740
BRACE20063630
BRACE20063780
BRACE20063800
BRACE20063930
BRACE20064880//POLY(RC) BINDING PROTEIN 2 (PUTATIVE HETEROGENEOUS
NUCLEAR RIBONUCLEOPROTEIN X) (HNRNP X) (CTBP)
(CBP).//1.80E-129//207aa//81%//Q61990
BRACE20067430
BRACE20068590//HYPOTHETICAL ZINC FINGER PROTEIN
KIAA0961.//2.70E-155//504aa//56%//Q9Y2G7
BRACE20069090
BRACE20081720
BRACE20082950
BRACE20090440
BRACE20096200//Homo sapiens sir2-related protein type 7 (SIRT7)
mRNA, complete cds.//1.00E-162//305aa//99%//AF233395
BRACE20096540
BRACE20097320
BRACE20099570
BRACE20101700
BRACE20101710
BRACE20106690
BRACE20106840//Rattus norvegicus partial mRNA for CRM1
protein.//9.00E-59//120aa//100%//AJ238278
BRACE20107530//Rattus norvegicus putative peroxisomal
2,4-dienoyl-CoA reductase (DCR-AKL) mRNA, complete cds.//1.70E-48
//108aa//91%//AF044574
BRACE20108130//Homo sapiens RAB-like protein 2B (RABL2B) mRNA,
complete cds.//1.60E-43//92aa//100%//AF095352
BRACE20108880//MALEYLACETOACETATE ISOMERASE (EC 5.2.1.2) (MAAI)
(GLUTATHIONE TRANSFERASE ZETA 1) (EC
2.5.1.18).//5.90E-11//27aa//100%//043708
BRACE20109370
BRACE20109830
BRACE20111830
BRACE20114780
BRACE20115450
BRACE20115920//RHO-GTPASE-ACTIVATING PROTEIN 4 (RHO-GAP
HEMATOPOIETIC PROTEIN C1) (P115)
(KIAA0131).//9.70E-73//291aa//52%//P98171
BRACE20116110
BRACE20116460//ATP SYNTHASE DELTA CHAIN, MITOCHONDRIAL PRECURSOR
(EC 3.6.1.34).//1.00E-20//48aa//100%//P30049
BRACE20118380
BRACE20121850
BRACE20136240
BRACE20141080
BRACE20142320
BRACE20142570
BRACE20147800
BRACE20148210
BRACE20148240//Gsp1p [Saccharomyces
cerevisiae].//1.00E-05//75aa//35%//NP.sub.--013396
BRACE20150310
BRACE20151320//Drosophila melanogaster Oregon R cytoplasmic basic
protein (deltex) mRNA, complete
cds.//6.10E-35//202aa//41%//U09789
BRACE20152870
BRACE20153680//Rattus norvegicus putative four repeat ion channel
mRNA, complete cds.//4.10E-107//209aa//99%//AF078779
BRACE20154120//Shb=Src homology 2
protein//2.60E-23//79aa//48%//AAB29780
BRACE20163150
BRACE20163350//MYELIN PO PROTEIN
PRECURSOR.//8.20E-08//92aa//33%//P20938
BRACE20165830
BRACE20171240
BRACE20172980//translation initiation factor eIF3
[Schizosaccharomyces pombe]//5.60E-06//136aa//30%//CAB11250
BRACE20175870
BRACE20177200//RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN (RAN BINDING
PROTEIN 1) (RANBP1).//9.90E-32//63aa//100%//P34022
BRACE20179340
BRACE20185680//ACETYL-COENZYME A SYNTHETASE (EC 6.2.1.1)
(ACETATE--COA LIGASE) (ACYL-ACTIVATING
ENZYME).//1.40E-16//94aa//40%//Q01576
BRACE20188470//ATP-binding cassette, sub-family A member
8//1.70E-115//457aa//50%//NP.sub.--009099
BRACE20190040
BRACE20190440
BRACE20192440//TRANSLATION INITIATION FACTOR
IF-3.//1.20E-09//161aa//26%//P47438
BRACE20195100
BRACE20201570
BRACE20210140
BRACE20220300
BRACE20223280
BRACE20223330
BRACE20224480
BRACE20224500
BRACE20228480
BRACE20229280
BRACE20230700
BRACE20232840//ATP-binding cassette, sub-family E, member
1//0//560aa//75%//NP.sub.--002931
BRACE20235400
BRACE20237270//Human WW domain binding protein-2 mRNA, complete
cds.//6.10E-21//50aa//88%//U79458
BRACE20238000
BRACE20240740
BRACE20248260//H. sapiens PR264
mRNA.//1.50E-13//78aa//48%//X62447
BRACE20253160//putative trna-splicing endonuclease subunit
[Schizosaccharomyces pombe]//1.10E-11//148aa//32%//CAA21061
BRACE20253330//Homo sapiens Na+/H+ exchange regulatory co-factor
(NHERF) mRNA, complete cds.//5.50E-88//157aa//99%//AF036241
BRACE20257100//transcription factor (SMIF
gene)//2.00E-37//110aa//94%//NP.sub.--060873
BRACE20262930
BRACE20262940
BRACE20266750
BRACE20267250
BRACE20269200
BRACE20269710
BRACE20273890//Human phosphotyrosine independent ligand p62B B-cell
isoform for the Lck SH2 domain mRNA, partial
cds.//5.70E-25//100aa//65%//U46752
BRACE20274080
BRACE20276430//Homo sapiens. retinoblastoma-associated protein
RAP140 mRNA, complete cds.//4.70E-106//203aa//100%//AF180425
BRACE20283920
BRACE20284100//Homo sapiens beta-dystrobrevin (BDTN) mRNA, complete
cds.//7.20E-121//237aa//100%//AF022728
BRACE20286360
BRACE20287410
BRALZ20013500//Homo sapiens prostate stem cell antigen (PSCA) mRNA,
complete cds.//3.30E-06//122aa//32%//AF043498
BRALZ20014450
BRALZ20017430//H. sapiens mRNA for protein phosphatase
5.//1.70E-41//99aa//87%//X89416
BRALZ20018340//H. sapiens mRNA for glutamine transaminase
K.//4.70E-93//114aa//98%//X82224
BRALZ20019660
BRALZ20054710//Mus musculus mRNA for cysteine and histidine-rich
protein (Chrp gene).//1.70E-163//280aa//99%//AJ251516
BRALZ20058880
BRALZ20059500
BRALZ20064740
BRALZ20065600
BRALZ20069760
BRALZ20073760//MONOCYTE TO MACROPHAGE DIFFERENTIATION
PROTEIN.//8.40E-41//76aa//69%//Q15546
BRALZ20075450
BRALZ20075760
BRALZ20077900//anaphase-promoting complex 1; meiotic checkpoint
regulator//3.00E-91//190aa//92%//NP.sub.--073153
BRALZ20077930//Xenopus laevis 4g2 mRNA, complete
cds.//1.20E-191//501aa//71%//AF182319
BRALZ20080310
BRALZ20088690
BRAMY10001300//Homo sapiens MAGE-E1b mRNA, complete
cds.//5.40E-78//140aa//97%//AB040528
BRAMY10001570
BRAMY20000520//HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1/C2
(HNRNP C1 AND HNRNP C2).//7.10E-70//293aa//53%//P07910
BRAMY20000860
BRAMY20002770
BRAMY20004110
BRAMY20011140
BRAMY20025840//H. sapiens mRNA from TYL
gene.//7.10E-103//198aa//98%//X99688
BRAMY20039260
BRAMY20045240
BRAMY20054880//Rattus norvegicus KPL2 (Kpl2) mRNA, complete
cds.//1.40E-43//155aa//59%//AF102129
BRAMY20060920//reduced in osteosclerosis
transporter//1.50E-09//60aa//53%//NP.sub.--112471
BRAMY20063970
BRAMY20071850
BRAMY20102080
BRAMY20103570
BRAMY20104640//Mus musculus mRNA for serine/threonine protein
kinase.//1.80E-140//345aa//75%//AJ250840
BRAMY20110640
BRAMY20111960
BRAMY20112800
BRAMY20116790
BRAMY20120910//GRG PROTEIN (ESP1 PROTEIN) (AMINO ENHANCER OF SPLIT)
(AES-1/AES-2).//1.60E-97//188aa//100%//Q08117
BRAMY20121190
BRAMY20121620//Mus musculus kinesin light chain 2 (Klc2) mRNA,
complete cds.//1.80E-256//500aa//85%//AF055666
BRAMY20124260//Rattus norvegicus transmembrane receptor Unc5H2
mRNA, complete cds.//2.80E-286//554aa//92%//U87306
BRAMY20134140//ATPase, H+ transporting, lysosomal (vacuolar proton
pump) 9 kD//4.60E-29//52aa//59%//NP.sub.--003936
BRAMY20135900//CELLULAR APOPTOSIS SUSCEPTIBILITY
PROTEIN.//2.00E-07//146aa//23%//P55060
BRAMY20136210
BRAMY20137560
BRAMY20144620
BRAMY20147540
BRAMY20148130
BRAMY20152110
BRAMY20153110//TRYPTOPHAN 5-MONOOXYGENASE (EC 1.14.16.4)
(TRYPTOPHAN 5-HYDROXYLASE).//8.50E-58//201aa//58%//Q92142
BRAMY20157820//PUTATIVE KINESIN-LIKE PROTEIN
C2F12.13.//1.10E-90//341aa//50%//014343
BRAMY20160700
BRAMY20162510//MELANOMA-ASSOCIATED ANTIGEN B2 (MAGE-B2 ANTIGEN)
(DAM6).//1.30E-33//209aa//35%//015479
BRAMY20163250
BRAMY20163270
BRAMY20167060
BRAMY20167710
BRAMY20168920
BRAMY20170140
BRAMY20174550//Homo sapiens ATP-binding cassette protein M-ABC1
mRNA, nuclear gene encoding mitochondrial protein, complete
cds.//0//648aa//98%//AF047690
BRAMY20178640
BRAMY20181220
BRAMY20182730
BRAMY20183080
BRAMY20184670//Homo sapiens mRNA for ALEX1, complete
cds.//6.40E-14//139aa//27%//AB039670
BRAMY20195090
BRAMY20196000
BRAMY20204450
BRAMY20205740
BRAMY20210400//Homo sapiens thyroid hormone receptor-associated
protein complex component TRAP150 mRNA, complete
cds.//2.80E-16//141aa//39%//AF117756
BRAMY20211390//seven in absentia (Drosophila) homolog 1 [Homo
sapiens]//3.70E-156//282aa//99%//NP.sub.--003022
BRAMY20211420//Homo sapiens mRNA for LAK-4p, complete
cds.//3.00E-31//224aa//33%//AB002405
BRAMY20213100//Xenopus laevis Mi-2 histone deacetylase complex
protein 66 mRNA, complete cds.//2.10E-66//394aa//44%//AF171099
BRAMY20215230
BRAMY20217460//Homo sapiens cardiac voltage gated potassium channel
modulatory subunit mRNA, complete cds, alternatively
spliced.//3.70E-81//158aa//98%//AF295530
BRAMY20218250//putative four repeat ion channel [Rattus
norvegicus]//0//588aa//99%//AF078779
BRAMY20218670
BRAMY20229800
BRAMY20229840
BRAMY20230600
BRAMY20231720
BRAMY20240040//Homo sapiens suppressor of white apricot homolog 2
(SWAP2) mRNA, complete cds.//3.20E-301//642aa//90%//AF042800
BRAMY20242470//CORONIN-LIKE PROTEIN P57 (CORONIN
1A).//1.60E-70//210aa//66%//P31146
BRAMY20245300//Homo sapiens putative prostate cancer susceptibility
protein HPC2/ELAC2 mRNA, complete cds.//0//737aa//99%//AF304370
BRAMY20247110//Mus musculus semaphorin cytoplasmic
domain-associated protein 3A (Semcap3) mRNA, complete
cds.//6.00E-117//366aa//63%//AF127084
BRAMY20247280
BRAMY20248490
BRAMY20250240
BRAMY20250320
BRAMY20252180
BRAMY20252720//Homo sapiens mRNA for thioredoxin reductase II
alpha, partial cds.//1.60E-84//161aa//99%//AB019694
BRAMY20260910//Homo sapiens zinc finger DNA binding protein 99
(ZNF281) mRNA, complete cds.//0//811aa//99%//AF125158
BRAMY20261680
BRAMY20266850//Homo sapiens oxidation protection protein (0XR1)
mRNA, complete cds.//4.50E-57//193aa//56%//AF309387
BRAMY20267130
BRAMY20268990
BRAMY20270730//Fugu rubripes zinc finger protein, isotocin, fatty
acid binding protein, sepiapterin reductase and vasotocin genes,
complete cds.//7.80E-155//398aa//66%//U90880
BRAMY20271400//RHO-GUANINE NUCLEOTIDE EXCHANGE FACTOR(RHOGEF)
(RIP2).//0//946aa//80%//P97433
BRAMY20273960
BRAMY20277140
BRAMY20277170//VOLTAGE-GATED POTASSIUM CHANNEL PROTEIN KV3.2
(KSHIIIA).//1.00E-290//538aa//97%//P22462
BRAMY20280720
BRAMY20284910
BRAMY20285160//COMPLEMENT C3 PRECURSOR [CONTAINS: C3A
ANAPHYLATOXIN].//1.90E-79//148aa//100%//P01024
BRAMY20285930
BRAMY20286820
BRAWH10000930
BRAWH20002320//Manduca sexta death-associated small cytoplasmic
leucine-rich protein SCLP mRNA, complete
cds.//3.50E-18//167aa//31%//AF250910
BRAWH20004600//Mus musculus mRNA for NAKAP95, complete
cds.//8.40E-184//336aa//84%//AB028921
BRAWH20011710//cytoplasmic linker
2//1.60E-96//316aa//59%//NP.sub.--034120
BRAWH20012390//Trichomonas vaginalis mRNA for centrin (ce1
gene).//4.70E-14//153aa//28%//AJ249457
BRAWH20012410
BRAWH20014920
BRAWH20015350
BRAWH20015890
BRAWH20016620//Homo sapiens mRNA for MOK protein kinase, complete
cds.//3.40E-82//160aa//99%//AB022694
BRAWH20016660
BRAWH20016860
BRAWH20017010//Homo sapiens testes development-related NYD-SP22
mRNA, complete cds.//1.00E-23//56aa//92%//AF367474
BRAWH20018730//HYPOTHETICAL 56.4 KDA PROTEIN IN SRS2-SIP4
INTERGENIC REGION.//1.90E-46//503aa//31%//P47026
BRAWH20028110//Homo sapiens actin-binding double-zinc-finger
protein (abLIM) mRNA, complete
cds.//9.40E-168//416aa//61%//AF005654
BRAWH20029630//Homo sapiens bet3 (BET3) mRNA, complete
cds.//2.40E-47//96aa//100%//AF041432
BRAWH20030250
BRAWH20064050//FIBULIN-1, ISOFORM C
PRECURSOR.//6.30E-42//337aa//33%//P23144
BRAWH20075700//ZINC FINGER PROTEIN ZFP-1 (MKR1
PROTEIN).//1.60E-159//332aa//84%//P08042
BRAWH20096780//ZINC FINGER PROTEIN 184
(FRAGMENT).//5.00E-140//514aa//52%//Q99676
BRAWH20100690
BRAWH20101360
BRAWH20103180
BRAWH20103290//GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS (DBL'S BIG
SISTER) (MCF2 TRANSFORMING SEQUENCE-LIKE PROTEIN) (KIAA0362)
(FRAGMENT).//0//756aa//99%//015068
BRAWH20105840//HYPOTHETICAL 27.0 KDA PROTEIN IN SPOOA-MMGA
INTERGENIC REGION.//1.70E-21//156aa//32%//P54527
BRAWH20106180
BRAWH20107540
BRAWH20110660
BRAWH20110790
BRAWH20110960//Homo sapiens mRNA for 26S proteasome subunit p40.5,
complete cds.//1.50E-175//378aa//90%//AB009398
BRAWH20111550
BRAWH20112940//POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE (EC
2.4.1.41) (PROTEIN-UDP ACETYLGALACTOSAMINYLTRANSFERASE)
(UDP-GALNAC:POLYPEPTIDE, N-ACETYLGALACTOSAMINYLTRANSFERASE)
(GALNAC-T1).//1.10E-59//369aa//36%//Q07537
BRAWH20113430//COLD-INDUCIBLE RNA-BINDING PROTEIN (GLYCINE-RICH
RNA-BINDING PROTEIN CIRP) (A18
HNRNP).//9.30E-52//104aa//96%//Q14011
BRAWH20114000//GLUTAMATE DEHYDROGENASE 1 PRECURSOR (EC 1.4.1.3)
(GDH).//5.90E-233//426aa//98%//P00367
BRAWH20117950//LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1)
(PROLINE-BETA-NAPHTHYLAMIDASE).//1.80E-78//364aa//42%//Q29550
BRAWH20118230//BONE MORPHOGENETIC PROTEIN 7 PRECURSOR (BMP-7)
(OSTEOGENIC PROTEIN 1) (OP-1).//7.60E-74//85aa//98%//P18075
BRAWH20121640//transporter protein; system N1 Na+ and H+-coupled
glutamine transporter//1.00E-106//450aa//61%//NP.sub.--006832
BRAWH20122580
BRAWH20122770
BRAWH20125380//DIHYDRODIPICOLINATE SYNTHASE (EC 4.2.1.52)
(DHDPS).//6.40E-15//121aa//35%//Q57695
BRAWH20126190
BRAWH20126980
BRAWH20128270//BH3 INTERACTING DOMAIN DEATH AGONIST
(BID).//2.70E-100//195aa//99%//P55957
BRAWH20132190//Homo sapiens putative N-acetyltransferase Camello 2
(CML2) mRNA, complete cds.//1.80E-17//110aa//44%//AF185571
BRAWH20137480//actin binding LIM protein
1//2.80E-70//181aa//55%//NP.sub.--006710
BRAWH20138660//Homo sapiens stonin 2 mRNA, complete
cds.//1.50E-171//322aa//99%//AF255309
BRAWH20139410
BRAWH20142340
BRAWH20147290
BRAWH20149340//GUANINE NUCLEOTIDE RELEASING PROTEIN (GNRP) (P140
RAS-GRF).//4.10E-129//290aa//83%//P28818
BRAWH20155950
BRAWH20158530
BRAWH20160280
BRAWH20162690
BRAWH20164460//TAT-BINDING HOMOLOG
7.//1.60E-95//366aa//54%//P54816
BRAWH20166790
BRAWH20171030//Homo sapiens putative helicase RUVBL mRNA, complete
cds.//2.80E-209//324aa//100%//AF218313
BRAWH20173050
BRAWH20182060
BRAWH20185060
BRCAN10001490//chromobox homolog
6//2.10E-40//82aa//100%//NP.sub.--055107
BRCAN20003460//outer arm dynein intermediate chain
1//5.60E-57//159aa//49%//T02761
BRCAN20006200
BRCAN20006390
BRCAN20054490//Sus scrofa mRNA for 54 kDa vacuolar H(+)-ATPase
subunit, beta isoform.//1.00E-117//229aa//96%//AJ223758
BRCAN20060190
BRCAN20064010
BRCAN20071190//FAF1 PROTEIN (FAS-ASSOCIATED FACTOR
1).//4.00E-225//433aa//96%//P54731
BRCAN20091560//Xenopus laevis mRNA for Nfr1, complete
cds.//1.20E-256//605aa//77%//D86491
BRCAN20103740//P2X PURINOCEPTOR 7 (ATP RECEPTOR) (P2.times.7)
(PURINERGIC RECEPTOR) (P2Z
RECEPTOR).//2.20E-18//60aa//78%//Q99572
BRCAN20124080
BRCAN20126130
BRCAN20143700
BRCAN20147880
BRCAN20216690
BRCAN20224720//PROTOPORPHYRINOGEN OXIDASE (EC 1.3.3.4)
(PPO).//4.40E-132//254aa//100%//P50336
BRCAN20237240
BRCAN20263400
BRCAN20273100
BRCAN20273340
BRCAN20273550
BRCAN20273640//lymphocyte specific formin related
protein//3.00E-80//350aa//56%//NP.sub.--062653
BRCAN20275130
BRCAN20279700//Homo sapiens copine I mRNA, complete
cds.//2.10E-32//82aa//68%//U83246
BRCAN20280210//H. sapiens HZF10 mRNA for zinc finger
protein.//3.30E-54//219aa//49%//X78933
BRCAN20280360//Homo sapiens phosphatidic acid phosphohydrolase
type-2c mRNA, complete cds.//8.20E-22//213aa//28%//AF047760
BRCAN20280400
BRCAN20283190//CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1
(CHD-1).//1.20E-131//235aa//99%//014646
BRCAN20283380//Mus musculus mRNA for serine hydrolase protein,
isoform 2 (serh1 gene).//6.50E-45//103aa//80%//AJ245737
BRCAN20284600
BRCAN20285450
BRCOC10000870
BRCOC20001860//Homo sapiens endoplasmic reticulum alpha-mannosidase
I mRNA, complete cds.//6.30E-154//282aa//99%//AF145732
BRCOC20004040//Rattus norvegicus sphingosine 1-phosphate receptor
Edg-8 (Edg-8) mRNA, complete
cds.//4.80E-108//265aa//81%//AF233649
BRCOC20004870
BRCOC20006370//PUTATIVE SURFACE GLYCOPROTEIN C210RF1 PRECURSOR
(C210RF3).//4.00E-67//144aa//88%//P53801
BRCOC20008160//Homo sapiens mRNA for actin binding protein ABP620,
complete cds.//4.20E-155//777aa//40%//AB029290
BRCOC20008500//Human ras inhibitor mRNA, 3'
end.//4.60E-229//428aa//100%//M37190
BRCOC20020850
BRCOC20021550//Rattus norvegicus mRNA for Nadrin, complete
cds.//1.90E-56//247aa//55%//AB042827
BRCOC20023230
BRCOC20026640
BRCOC20027510//RAS SUPPRESSOR PROTEIN 1 (RSU-1) (RSP-1 PROTEIN)
(RSP-1).//2.20E-18//178aa//34%//Q15404
BRCOC20031000
BRCOC20031250//TRIOSEPHOSPHATE ISOMERASE (EC 5.3.1.1)
(TIM).//7.10E-38//92aa//82%//P48500
BRCOC20031870
BRCOC20035130//14-3-3 PROTEIN EPSILON (MITOCHONDRIAL IMPORT
STIMULATION FACTOR L SUBUNIT) (PROTEIN KINASE C INHIBITOR
PROTEIN-1) (KCIP-1) (14-3-3E).//1.00E-29//71aa//88%//P42655
BRCOC20037320//PUTATIVE IMPORTIN BETA-4 SUBUNIT (KARYOPHERIN BETA-4
SUBUNIT).//5.00E-75//937aa//26%//060100
BRCOC20037400
BRCOC20041750
BRCOC20055420//GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE 2 (EC
2.3.1.97) (PEPTIDE N-MYRISTOYLTRANSFERASE 2) (MYRISTOYL-COA:PROTEIN
N-MYRISTOYLTRANSFERASE 2) (NMT
2).//7.90E-229//421aa//99%//060551
BRCOC20059510//B. taurus myosin IB mRNA, complete
CDS.//1.40E-29//117aa//53%//Z22852
BRCOC20074760//CDC4-LIKE PROTEIN
(FRAGMENT).//4.50E-90//366aa//48%//P50851
BRCOC20077690
BRCOC20078640
BRCOC20090520
BRCOC20091960//CDC42-binding protein kinase beta (DMPK-like) [Homo
sapiens]//1.50E-71//140aa//100%//NP.sub.--006026
BRCOC20093800
BRCOC20099370//Homo sapiens SPG protein (SPG) mRNA, complete
cds.//0//576aa//97%//AF302154
BRCOC20101230////7.40E-32//227aa//35%//
BRCOC20105100
BRCOC20107300//Homo sapiens GTT1 mRNA, complete
cds.//3.60E-44//90aa//98%//AF270647
BRCOC20110100
BRCOC20114180
BRCOC20117690
BRCOC20119960
BRCOC20121720
BRCOC20122290
BRCOC20128130
BRCOC20134480
BRCOC20135730
BRCOC20136750
BRCOC20144000//DNA REPAIR PROTEIN
RAD8.//5.50E-14//111aa//36%//P36607
BRCOC20147480
BRCOC20148330
BRCOC20155970
BRCOC20158240
BRCOC20176520//Rattus norvegicus mRNA for type II brain 4.1,
complete cds.//2.30E-127//269aa//79%//AB032827
BRCOC20178270//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN
HPF1).//4.90E-101//272aa//64%//P51522
BRCOC20178560//PINCH PROTEIN (PARTICULARY INTERESTING NEW CYS-HIS
PROTEIN).//9.50E-130//247aa//85%//P48059
BRHIP10001290//Homo sapiens GalNAc-T9 mRNA for
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase, complete
cds.//1.10E-108//299aa//63%//AB040672
BRHIP10001740
BRHIP20000870
BRHIP20001630
BRHIP20003120//Homo sapiens reticulon gene family protein (RTN3)
mRNA, complete cds.//2.20E-92//190aa//98%//AF059524
BRHIP20005340//GAMMA-INTERFERON-INDUCIBLE PROTEIN IFI-16
(INTERFERON-INDUCIBLE MYELOID DIFFERENTIATION TRANSCRIPTIONAL
ACTIVATOR).//2.10E-157//407aa//77%//Q16666
BRHIP20005530//UBIQUITIN-ACTIVATING ENZYME E1
1.//1.00E-59//318aa//41%//Q02053
BRHIP20096170//Homo sapiens cellular repressor of E1A-stimulated
genes CREG mRNA, complete cds.//9.70E-35//174aa//39%//AF084523
BRHIP20096850//ALANINE AMINOTRANSFERASE (EC 2.6.1.2)
(GLUTAMIC-PYRUVIC TRANSAMINASE) (GPT) (GLUTAMIC--ALANINE
TRANSAMINASE).//1.60E-166//423aa//69%//P25409
BRHIP20103090//VACUOLAR ATP SYNTHASE SUBUNIT AC45 PRECURSOR (EC
3.6.1.34) (V-ATPASE AC45 SUBUNIT).//2.00E-12//82aa//47%//P40682
BRHIP20104440
BRHIP20105710
BRHIP20106100//GAR2 PROTEIN.//1.50E-19//199aa//31%//P41891
BRHIP20107440
BRHIP20110800
BRHIP20111200
BRHIP20115080//DYNAMIN 2 (DYNAMIN
UDNM).//4.80E-63//123aa//95%//P39054
BRHIP20115760
BRHIP20118380
BRHIP20118910
BRHIP20119330//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//6.80E-207//651aa//54%//Q05481
BRHIP20121410
BRHIP20123140
BRHIP20129720
BRHIP20132860//Homo sapiens rhophilin-like protein mRNA, complete
cds.//5.40E-144//298aa//93%//AF268032
BRHIP20135100
BRHIP20137230//Homo sapiens mRNA for
paralemin.//1.70E-37//352aa//35%//Y16278
BRHIP20139720
BRHIP20140630
BRHIP20142850
BRHIP20143730
BRHIP20143860
BRHIP20149540
BRHIP20153560
BRHIP20153600//Xenopus laevis RRM-containing protein SEB-4 mRNA,
complete cds.//1.50E-72//148aa//93%//AF223427
BRHIP20167880//Mus musculus left-right dynein (Lrd) mRNA, complete
cds.//8.10E-22//119aa//54%//AF183144
BRHIP20169680
BRHIP20169900
BRHIP20170100
BRHIP20173150
BRHIP20174040//CGMP-DEPENDENT 3',5'-CYCLIC PHOSPHODIESTERASE (EC
3.1.4.17) (CYCLIC GMP STIMULATED PHOSPHODIESTERASE)
(CGS-PDE).//0//857aa//99%//000408
BRHIP20175420//Mus musculus partial mRNA for stretch responsive
protein 278 (sr278 gene).//6.60E-36//170aa//50%//AJ250191
BRHIP20176420//HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1/C2
(HNRNP C1 AND HNRNP C2).//9.30E-68//292aa//52%//P07910
BRHIP20179200
BRHIP20180140
BRHIP20183690
BRHIP20186120
BRHIP20186500
BRHIP20189980//FLAGELLAR WD-REPEAT PROTEIN
PF20.//2.90E-41//210aa//46%//P93107
BRHIP20190070
BRHIP20191490//interferon, alpha-inducible protein
27//2.60E-36//92aa//95%//NP.sub.--005523
BRHIP20191770
BRHIP20191860//TRANSCRIPTION FACTOR 4 (IMMUNOGLOBULIN TRANSCRIPTION
FACTOR 2) (ITF-2) (SL3-3 ENHANCER FACTOR 2)
(SEF-2).//0//569aa//99%//P15884
BRHIP20194940//Homo sapiens A-kinase anchoring protein 220 mRNA,
complete cds.//1.30E-23//190aa//37%//AF176555
BRHIP20195890//FORKHEAD BOX PROTEIN D2 (FORKHEAD-RELATED PROTEIN
FKHL17) (FORKHEAD-RELATED TRANSCRIPTION FACTOR 9)
(FREAC-9).//9.10E-07//104aa//31%//060548
BRHIP20196410
BRHIP20198190
BRHIP20205090
BRHIP20207430
BRHIP20207990
BRHIP20208270
BRHIP20208420
BRHIP20208590
BRHIP20214950
BRHIP20217620
BRHIP20218580//Mus musculus betaPix-b mRNA, complete
cds.//5.10E-100//196aa//94%//AF247654
BRHIP20222280//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)
(HTF1).//1.70E-217//505aa//75%//Q03923
BRHIP20227080
BRHIP20230710
BRHIP20232290
BRHIP20233090
BRHIP20234380
BRHIP20236950
BRHIP20238600//WD-REPEAT PROTEIN
SAZD.//3.30E-95//182aa//99%//Q12788
BRHIP20238690
BRHIP20238880
BRHIP20240460
BRHIP20243470//GALECTIN-3 (GALACTOSE-SPECIFIC LECTIN 3) (MAC-2
ANTIGEN) (IGE-BINDING PROTEIN) (35 KDA LECTIN) (CARBOHYDRATE
BINDING PROTEIN 35) (CBP 35) (LAMININ-BINDING PROTEIN) (LECTIN
L-29).//1.10E-16//114aa//42%//P38486
BRHIP20249110//hexokinase 1//0//912aa//71%//NP.sub.--000179
BRHIP20252450//Mus musculus Syne-1B mRNA, partial
cds.//1.40E-159//980aa//33%//AF281870
BRHIP20253660//Rattus norvegicus mRNA for Proline Rich Synapse
Associated Protein 1A (ProSAP1A
gene).//1.90E-120//239aa//92%//AJ249562
BRHIP20254480
BRHIP20277620
BRHIP20283030//CADHERIN-RELATED TUMOR SUPPRESSOR PRECURSOR (FAT
PROTEIN).//1.40E-88//881aa//29%//P33450
BRHIP20284800
BRHIP20285830//TYPE III INTERMEDIATE
FILAMENT.//8.20E-10//88aa//35%//P23729
BRHIP20285930//Homo sapiens IL-1 receptor accessory protein mRNA,
complete cds.//3.30E-08//104aa//32%//AF029213
BRHIP30001110
BRHIP30004570//P-SELECTIN PRECURSOR (GRANULE MEMBRANE PROTEIN 140)
(GMP-140) (PADGEM) (CD62P) (LEUKOCYTE-ENDOTHELIAL CELL ADHESION
MOLECULE 3) (LECAM3).//3.60E-32//281aa//31%//Q01102
BRHIP30004880//H. sapiens mRNA for titin protein (clone
hh1-hh54).//9.60E-85//812aa//26%//X90568
BRSSN10000920
BRSSN20003120//METABOTROPIC GLUTAMATE RECEPTOR
PRECURSOR.//7.00E-08//257aa//22%//P91685
BRSSN20006340
BRSSN20013420//histone deacetylase 6 [Homo sapiens]
//0//811aa//99%//NP.sub.--006035
BRSSN20014260//RIBONUCLEASE
INHIBITOR.//1.70E-10//195aa//29%//P29315
BRSSN20015030
BRSSN20015790//ORNITHINE DECARBOXYLASE (EC 4.1.1.17)
(ODC).//9.00E-102//352aa//53%//P00860
BRSSN20018690//Homo sapiens NY-REN-25 antigen mRNA, partial
cds.//9.30E-41//88aa//100%//AF155103
BRSSN20021600//RING CANAL PROTEIN (KELCH
PROTEIN).//3.60E-59//510aa//31%//Q04652
BRSSN20028570
BRSSN20038200//RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE
2 (RALGDS-LIKE FACTOR) (RAS-ASSOCIATED PROTEIN
RAB2L).//3.90E-18//458aa//25%//015211
BRSSN20038410
BRSSN20039370//ZINC FINGER PROTEIN 7 (ZINC FINGER PROTEIN KOX4)
(ZINC FINGER PROTEIN HF. 16).//2.50E-38//94aa//52%//P17097
BRSSN20043040
BRSSN20046570
BRSSN20046790//ZINC FINGER PROTEIN
135.//8.60E-81//231aa//60%//P52742
BRSSN20046860
BRSSN20066110//Homo sapiens mRNA for mucolipidin, short form (ML4
gene).//1.70E-26//121aa//49%//AJ293659
BRSSN20097020
BRSSN20101100//GRG PROTEIN (ESP1 PROTEIN) (AMINO ENHANCER OF SPLIT)
(AES-1/AES-2).//2.50E-10//70aa//51%//Q08117
BRSSN20105870
BRSSN20105960
BRSSN20108300
BRSSN20117990
BRSSN20120810//SERINE PROTEASE HEPSIN (EC 3.4.21.-) (TRANSMEMBRANE
PROTEASE, SERINE 1).//9.80E-144//254aa//100%//P05981
BRSSN20121030
BRSSN20137020
BRSSN20142940
BRSSN20146100//ADENYLATE CYCLASE, OLFACTIVE TYPE (EC 4.6.1.1)
(ADENYLATE CYCLASE TYPE III) (ATP PYROPHOSPHATE-LYASE) (ADENYLYL
CYCLASE).//0//389aa//90%//P21932
BRSSN20151990
BRSSN20152380
BRSSN20159070
BRSSN20159820
BRSSN20169050
BRSSN20176820//Mus musculus p300 transcriptional cofactor JMY mRNA,
complete cds.//8.50E-297//640aa//89%//AF201390
BRSSN20177570
BRSSN20187310//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R)
(ANKYRINS 2.1 AND 2.2).//3.20E-26//306aa//30%//P16157
BRSTN10000830
BRSTN20000580
BRSTN20002200
BRSTN20005360//TRANSLATION INITIATION FACTOR
IF-2.//1.20E-07//205aa//26%//060841
BRTHA20000570
BRTHA20004740//HYPOTHETICAL 41.6 KDA PROTEIN IN IMP1-HLJ1INTERGENIC
REGION (RF1095).//1.60E-16//310aa//27%//P28625
BRTHA20046290//NOVEL ANTIGEN 2 (NAG-2)
(TSPAN-4).//7.30E-84//153aa//100%//014817
BRTHA20046390
BRTHA20046420 CD34C30001250 CD34C30003140 CD34C30004240//H. sapiens
graf gene.//1.10E-140//270aa//100%//Y10388 CD34C30004940
COLON10001350//IG ALPHA-1 CHAIN C
REGION.//1.70E-196//353aa//99%//P01876
COLON20043180
COLON20093370
CTONG10000100//GUFA PROTEIN.//2.10E-31//156aa//45%//Q06916
CTONG10000220//Mus musculus cerebellar postnatal development
protein-1 (Cpd1) mRNA, partial
cds.//1.80E-101//220aa//90%//U89345
CTONG10000620
CTONG10000930
CTONG10000940//CYCLIN-DEPENDENT KINASE 6 INHIBITOR(P18-INK6)
(CYCLIN-DEPENDENT KINASE 4 INHIBITOR C)
(P18-INK4C).//7.20E-13//131aa//35%//Q60772
CTONG10001650
CTONG10002770//PLECTIN.//2.00E-49//284aa//28%//P30427
CTONG20002180
CTONG20004690//CYTOCHROME B561 (CYTOCHROME
B-561).//2.80E-50//101aa//100%//P49447
CTONG20009770//26S PROTEASOME REGULATORY SUBUNIT S2 (P97) (TUMOR
NECROSIS FACTOR TYPE 1 RECEPTOR ASSOCIATED PROTEIN 2) (55.11
PROTEIN).//0//908aa//99%//Q13200
CTONG20014280//Xenopus laevis fizzy1 mRNA, complete
cds.//2.00E-82//479aa//38%//AF034578
CTONG20027090
CTONG20028410
CTONG20038890
CTONG20049410
CTONG20050280//ZINC FINGER PROTEIN ZFP-36
(FRAGMENT).//8.00E-149//490aa//55%//P16415
CTONG20052650//BYSTIN.//5.10E-60//120aa//99%//Q13895
CTONG20052900//FASCIN (ACTIN BUNDLING
PROTEIN).//7.30E-257//437aa//98%//Q16658
CTONG20075860//Homo sapiens mRNA for SPIN
protein.//3.90E-123//204aa//69%//Y14946
CTONG20076130//ZINC FINGER PROTEIN 185 (LIM-DOMAIN PROTEIN ZNF185)
(P1-A).//1.10E-158//327aa//89%//015231
CTONG20077790
CTONG20082690
CTONG20085950//ZINC FINGER PROTEIN
191.//5.80E-91//346aa//53%//014754
CTONG20091080//HOMEOBOX PROTEIN
DLX-1.//1.00E-54//134aa//84%//Q64317
CTONG20091320
CTONG20092570//Rattus norvegicus neural membrane protein 35 mRNA,
complete cds.//1.00E-55//300aa//49%//AF044201
CTONG20092580
CTONG20092680//Rattus norvegicus protein associating with small
stress protein PASS1 (Pass1) mRNA, complete
cds.//1.40E-11//98aa//40%//AF168362
CTONG20092700//Mus musculus transcriptional repressor RP58 (rp58)
mRNA, complete cds.//6.60E-18//162aa//35%//AF140224
CTONG20093950//Mus musculus zfh-4 mRNA for zinc-finger homeodomain
protein 4, complete cds.//0//473aa//90%//AB024499
CTONG20095270
CTONG20095290
CTONG20095340//PROBABLE CATION-TRANSPORTING ATPASE WO8D2.5 IN
CHROMOSOME IV (EC 3.6.1.-).//3.90E-134//500aa//37%//Q27533
CTONG20096430
CTONG20096750
CTONG20097660
CTONG20098440
CTONG20099380
CTONG20099550//TRICHOHYALIN.//4.20E-16//534aa//25%//Q07283
CTONG20099630
CTONG20100240//Mus musculus radial spokehead-L protein (Rshl1)
mRNA, complete cds.//1.60E-185//520aa//63%//AF329192
CTONG20101480
CTONG20103480
CTONG20105080
CTONG20105660
CTONG20106230
CTONG20106520//THREONINE SYNTHASE (EC
4.2.99.2).//6.70E-77//347aa//40%//Q42598
CTONG20108210
CTONG20114290//PUTATIVE IMPORTIN BETA-4 SUBUNIT (KARYOPHERIN BETA-4
SUBUNIT).//1.30E-75//937aa//27%//060100
CTONG20114740//Homo sapiens NY-REN-57 antigen mRNA, partial
cds.//1.70E-37//72aa//100%//AF155114
CTONG20118150//HYPOTHETICAL 100.6 KDA TRP-ASP REPEATS CONTAINING
PROTEIN C1672.07 IN CHROMOSOME
III.//2.10E-150//910aa//36%//014053
CTONG20118250//CARBONIC ANHYDRASE (EC 4.2.1.1) (CARBONATE
DEHYDRATASE).//3.30E-88//257aa//62%//Q92051
CTONG20119200//Homo sapiens NY-REN-57 antigen mRNA, partial
cds.//1.00E-18//41aa//100%//AF155114
CTONG20120770
CTONG20121010//ZINC FINGER PROTEIN 29
(ZFP-29).//7.80E-131//380aa//58%//Q07230
CTONG20121580//KINESIN-LIKE PROTEIN
KIF1A.//3.50E-148//395aa//59%//P33173
CTONG20124010
CTONG20124220//STEROL REGULATORY ELEMENT BINDING PROTEIN-1
(SREBP-1) (STEROL REGULATORY ELEMENT-BINDING TRANSCRIPTION FACTOR
1).//0//691aa//98%//P36956
CTONG20124470
CTONG20124730
CTONG20125540//PTB-ASSOCIATED SPLICING FACTOR
(PSF).//6.90E-07//144aa//29%//P23246
CTONG20125640//60S ACIDIC RIBOSOMAL PROTEIN PO
(L10E).//7.50E-137//306aa//89%//P05388
CTONG20126070
CTONG20127450//H. sapiens mRNA for Ndr protein
kinase.//4.50E-11//37aa//89%//Z35102
CTONG20128430//Human non-lens beta gamma-crystallin like protein
(AIM1) mRNA, partial cds.//8.40E-127//616aa//40%//U83115
CTONG20128470
CTONG20129960//Mus musculus F-box protein FBX18 mRNA, partial
cds.//0//905aa//92%//AF184275
CTONG20131490
CTONG20131560//NEUROBLAST DIFFERENTIATION ASSOCIATED PROTEIN AHNAK
(DESMOYOKIN) (FRAGMENTS).//0//632aa//99%//Q09666
CTONG20132220
CTONG20133390//ZINC FINGER PROTEIN
135.//1.00E-139//416aa//57%//P52742
CTONG20133480
CTONG20133520//ZINC FINGER PROTEIN
228.//1.50E-163//670aa//50%//Q9UJU3
CTONG20136300
CTONG20138030
CTONG20139070
CTONG20139340
CTONG20139860//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete
cds.//3.50E-17//162aa//36%//AF121775
CTONG20140320
CTONG20140580//HepA-related
protein//8.80E-61//345aa//42%//NP.sub.--054859
CTONG20141650
CTONG20143690
CTONG20146300
CTONG20146970
CTONG20147050
CTONG20149460//RING CANAL PROTEIN (KELCH
PROTEIN).//1.20E-56//556aa//27%//Q04652
CTONG20149950
CTONG20150910
CTONG20153300//H. sapiens mRNA for tre oncogene (clone
210).//4.80E-214//259aa//78%//X63546
CTONG20153580//Homo sapiens leucine-rich repeats containing F-box
protein FBL3 mRNA, complete
cds.//4.80E-37//326aa//28%//AF186273
CTONG20155180
CTONG20155400
CTONG20156780//Rattus norvegicus PGC1 mRNA for PPAR gamma
coactivator, complete cds.//1.80E-72//176aa//46%//AB025784
CTONG20158040//UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE (EC
2.7.7.23) (ANTIGEN X) (AGX) (AGX-1) (SPERM-ASSOCIATED ANTIGEN
2).//4.90E-126//376aa//61%//Q16222
CTONG20158150
CTONG20158660//Rattus norvegicus mRNA for seven transmembrane
receptor, complete cds.//5.90E-99//632aa//36%//AB019120
CTONG20159530//GLYPICAN-1
PRECURSOR.//3.40E-118//222aa//100%//P35052
CTONG20160560
CTONG20161850
CTONG20162170
CTONG20163550
CTONG20164990
CTONG20165050
CTONG20186320//RING CANAL PROTEIN (KELCH
PROTEIN).//3.70E-19//290aa//26%//Q04652
CTONG20200310//mitotic control protein dis3
homolog//1.20E-113//655aa//36%//JE0110
CTONG20265130
CTONG20267700
CTONG20273610
D3OST10001090
D3OST10002670
D3OST10002700
D3OST20006180//Drosophila melanogaster slingshot mRNA, complete
cds.//9.20E-114//358aa//56%//AB036834
D3OST20006540
D3OST20007340
D3OST20013280//ARP2/3 COMPLEX 16 KDA SUBUNIT
(P16-ARC).//1.10E-48//103aa//99%//015511
D3OST20024170
D3OST20024360//Homo sapiens neuroendocrine differentiation factor
mRNA, complete cds.//4.70E-35//80aa//100%//AF219226
D3OST20024520
D3OST20036070
D3OST20037970
D3OST20038560
D3OST30002580
D3OST30002910
D6OST20003580//H. sapiens mRNA for aminopeptidase
P-like.//7.40E-70//103aa//99%//X95762
D6OST20004450
D6OST20005070
D9OST20000310
D9OST20002780
D9OST20015470//Mus musculus MPS1 gene and mRNA,
3'end.//4.60E-147//329aa//79%//L20315
D9OST20023970//CARTILAGE GLYCOPROTEIN-39 PRECURSOR (GP-39) (39 KDA
SYNOVIAL PROTEIN) (YKL-40) (CHITINASE-3 LIKE
1).//1.30E-17//44aa//90%//P36222
D9OST20026730//Homo sapiens caspase recruitment domain protein 7
mRNA, complete cds.//2.40E-141//524aa//40%//AF298548
D9OST20031370//Homo sapiens mRNA for partial putative
TCPTP-interacting protein (ptpip5
gene).//3.40E-39//176aa//48%//AJ242719
D9OST20033970//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//2.50E-152//541aa//52%//Q05481
D9OST20035800
D9OST20035940//BRAIN MITOCHONDRIAL CARRIER
PROTEIN-1.//9.10E-93//216aa//80%//095258
D9OST20040180//OLFACTORY RECEPTOR-LIKE PROTEIN
OLF4.//1.20E-106//301aa//64%//Q95157
DFNES10000030
DFNES10001850
DFNES20001530//ATAXIN 7 (SPINOCEREBELLAR ATAXIA TYPE 7
PROTEIN).//2.30E-25//98aa//57%//015265
DFNES20010910
DFNES20014040//TRICHOHYALIN.//1.70E-17//380aa//26%//P37709
DFNES20025880
DFNES20031920//Drosophila melanogaster mRNA for fucosyltransferase
homologue (FucTB gene).//8.40E-18//133aa//36%//AJ302046
DFNES20037420//G1 TO S PHASE TRANSITION PROTEIN 1 HOMOLOG
(GTP-BINDING PROTEIN GST1-HS).//1.00E-274//499aa//99%//P15170
DFNES20055270
DFNES20071130//PHOSPHOTRIESTERASE RELATED PROTEIN (PARATHION
HYDROLASE-RELATED PROTEIN).//4.40E-141//233aa//86%//Q60866
DFNES20082800
FCBBF10000240
FCBBF10000380
FCBBF10000630//Homo sapiens huntingtin interacting protein HYPB
mRNA, partial cds.//3.70E-16//36aa//100%//AF049610
FCBBF10000770//Homo sapiens REC8 mRNA, partial
cds.//6.10E-266//528aa//96%//AF132734
FCBBF10001150//Homo sapiens protocadherin beta 14 (PCDH-beta14)
mRNA, complete cds.//4.10E-308//717aa//79%//AF152493
FCBBF10001210//Homo sapiens mRNA for SHPS-1, complete
cds.//6.90E-22//135aa//43%//D86043
FCBBF10001550
FCBBF10001710//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN
HPF1).//1.90E-131//397aa//59%//P51522
FCBBF10001820//CITRATE LYASE BETA CHAIN (EC 4.1.3.6) (CITRASE)
(CITRYL-COA LYASE SUBUNIT) (EC
4.1.3.34).//3.70E-32//294aa//27%//053078
FCBBF10002430
FCBBF10002700
FCBBF10002800
FCBBF10003220
FCBBF10003670//QUEUINE TRNA-RIBOSYLTRANSFERASE (EC 2.4.2.29)
(TRNA-GUANINE TRANSGLYCOSYLASE) (GUANINE INSERTION
ENZYME).//2.60E-195//308aa//100%//P54578
FCBBF10003740
FCBBF10003760
FCBBF10003770//Homo sapiens mRNA for GRIP1
protein.//0//572aa//99%//AJ133439
FCBBF10004120
FCBBF10004370//ZINC FINGER PROTEIN 33A (ZINC FINGER PROTEIN KOX31)
(KIAA0065) (HA0946) (FRAGMENT).//3.30E-96//292aa//52%//Q06730
FCBBF10005060//CELLULAR RETINALDEHYDE-BINDING PROTEIN
(CRALBP).//8.40E-51//260aa//41%//P10123
FCBBF10005460//Mus musculus putative neuronal cell adhesion
molecule (Punc) mRNA, complete
cds.//9.20E-275//484aa//94%//AF026465
FCBBF10005500
FCBBF10005740//MITOCHONDRIAL CARRIER PROTEIN YMC2
PRECURSOR.//1.10E-27//194aa//38%//P38087
FCBBF20006780
FCBBF20014270//ACYL-COA-BINDING PROTEIN (ACBP) (DIAZEPAM BINDING
INHIBITOR) (DBI) (ENDOZEPINE)
(EP).//1.40E-34//85aa//81%//P45882
FCBBF20023700
FCBBF20032970
FCBBF20035280
FCBBF20042170//Homo sapiens NIBAN mRNA, complete
cds.//1.90E-177//345aa//100%//AB050477
FCBBF20042560
FCBBF20049300//NEURONAL OLFACTOMEDIN-RELATED ER LOCALIZED PROTEIN
PRECURSOR (NOEL) (1B426B).//7.70E-64//187aa//63%//Q62609
FCBBF20051220
FCBBF20054280
FCBBF20056370
FCBBF20059090//ZINC FINGER PROTEIN 44 (ZINC FINGER PROTEIN KOX7)
(FRAGMENT).//2.00E-08//96aa//34%//P15621
FCBBF20064520//HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEINS C1/C2
(HNRNP C1 AND HNRNP C2).//5.50E-70//293aa//53%//P07910
FCBBF20067810//SPOOB-ASSOCIATED GTP-BINDING
PROTEIN.//1.30E-51//275aa//42%//P20964
FCBBF20068820//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN
HPF1).//1.50E-74//216aa//62%//P51522
FCBBF20071860
FCBBF20072650
FCBBF20075560
FCBBF20076330
FCBBF30001840
FCBBF30007680//Homo sapiens general transcription factor 2-I
(GTF2I) mRNA, alternatively spliced product, complete
cds.//4.80E-56//141aa//72%//AF038968
FCBBF30008470
FCBBF30010810//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)
(HTF1).//7.10E-173//436aa//70%//Q03923
FCBBF30012350//CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II
GAMMA CHAIN (CAM-KINASE II GAMMA CHAIN) (EC 2.7.1.123) (CAMK-II,
GAMMA SUBUNIT).//8.80E-143//291aa//92%//P11730
FCBBF30012810//Homo sapiens ubiquitin-specific processing protease
mRNA, complete cds.//1.10E-123//450aa//49%//AF229438
FCBBF30013770//Rattus norvegicus dnchc2 mRNA for cytoplasmic dynein
heavy chain, complete cds.//0//806aa//93%//AB041881
FCBBF30015940//Chlamydomonas reinhardtii dhc1 gene for 1-alpha
dynein heavy chain.//4.90E-228//831aa//52%//AJ243806
FCBBF30016320
FCBBF30016570
FCBBF30018550//Homo sapiens putative zinc finger protein mRNA,
complete cds.//9.40E-90//560aa//35%//AF251039
FCBBF30019120
FCBBF30024750//SEMAPHORIN 4F PRECURSOR (SEMAPHORIN W) (SEMA
W).//2.00E-73//129aa//100%//095754
FCBBF30025560//NERVOUS-SYSTEM SPECIFIC OCTAMER-BINDING
TRANSCRIPTION FACTOR N-OCT 3 (BRAIN-SPECIFIC HOMEOBOX/POU DOMAIN
PROTEIN 2) (BRN-2 PROTEIN) [CONTAINS: N-OCT 5A; N-OCT
5B].//4.30E-171//203aa//100%//P20265
FCBBF30028180
FCBBF30033050
FCBBF30039020//GROWTH-ARREST-SPECIFIC PROTEIN
2.//1.80E-68//194aa//64%//043903
FCBBF30049550//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,
NONERYTHROID).//0//1016aa//99%//Q01484
FCBBF30052180
FCBBF30054440
FCBBF30057290//Homo sapiens GIOT-4 mRNA for gonadotropin inducible
transcription repressor-4, complete
cds.//8.90E-258//642aa//68%//AB021644
FCBBF30062880
FCBBF30070770
FCBBF30071520
FCBBF30078290
FCBBF30083620//PLEXIN 4 PRECURSOR (TRANSMEMBRANE PROTEIN
SEX).//5.80E-146//344aa//77%//P51805
FCBBF30083820//Homo sapiens C2H2 (Kruppe1-type) zinc finger protein
mRNA, complete cds.//1.50E-14//142aa//38%//AF159567
FCBBF30086440
FCBBF30090690//Homo sapiens HT017 mRNA, complete
cds.//8.60E-54//311aa//38%//AF225421
FCBBF30095260
FCBBF30123470
FCBBF30129630//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)
(HTF1).//9.50E-98//228aa//73%//Q03923
FCBBF30170590
FCBBF30172550
FCBBF30175310//ETHANOLAMINEPHOSPHOTRANSFERASE (EC 2.7.8.1)
(ETHPT).//2.10E-38//401aa//28%//P22140
FCBBF30178730
FCBBF30189490
FCBBF30190850//E-SELECTIN PRECURSOR (ENDOTHELIAL LEUKOCYTE ADHESION
MOLECULE 1) (ELAM-1) (LEUKOCYTE-ENDOTHELIAL CELL ADHESION MOLECULE
2) (LECAM2) (CD62E).//6.10E-30//275aa//31%//P16581
FCBBF30195640//Homo sapiens ALR-like protein mRNA, complete
cds.//9.10E-188//331aa//99%//AF264750
FCBBF30199610
FCBBF30215060
FCBBF30225660
FCBBF30233680
FCBBF30238870//PROTEIN KINASE C-BINDING PROTEIN NELL2 PRECURSOR
(NEL-LIKE PROTEIN 2).//O//641aa//99%//Q99435
FCBBF30240020
FCBBF30240960//ZINC FINGER PROTEIN
136.//8.30E-131//338aa//65%//P52737
FCBBF30242250
FCBBF30243640//PROTEIN ARGININE N-METHYLTRANSFERASE 2 (EC
2.1.1.-).//6.40E-53//102aa//100%//P55345
FCBBF30246230//Homo sapiens C2H2 (Kruppe1-type) zinc finger protein
mRNA, complete cds.//7.10E-17//141aa//40%//AF159567
FCBBF30246630//H. sapiens mRNA for ZYG
homologue.//4.80E-60//562aa//29%//X99802
FCBBF30247930//Rattus norvegicus clone C42 CDK5 activator-binding
protein mRNA, complete cds.//2.70E-73//162aa//87%//AF177477
FCBBF30250730//TRICHOHYALIN.//1.30E-10//240aa//27%//P22793
FCBBF30251420
FCBBF30252520//Homo sapiens bicaudal-D (BICD) mRNA, alternatively
spliced, partial cds.//2.50E-47//103aa//98%//U90030
FCBBF30252800//NDRG1 PROTEIN (DIFFERENTIATION-RELATED GENE 1
PROTEIN) (DRG1) (REDUCING AGENTS AND TUNICAMYCIN-RESPONSIVE
PROTEIN) (RTP) (NICKEL-SPECIFIC INDUCTION PROTEIN
CAP43).//1.30E-134//260aa//97%//Q92597
FCBBF30252850//Mus musculus peripherial benzodiazepine receptor
associated protein (Pap7) mRNA, complete
cds.//2.90E-46//185aa//50%//AF022770
FCBBF30262360
FCBBF30262510
FCBBF30266780
FCBBF30266920
FCBBF30278630
FCBBF30279030//Homo sapiens BNPI mRNA for brain-specific
Na-dependent inorganic phosphate cotransporter, complete
cds.//2.40E-120//222aa//100%//AB032436
FCBBF30281880//regulator of G-protein signalling 7 [Homo
sapiens].//2.00E-05//100aa//33%//NP.sub.--002915
FCBBF30284720
FCBBF30285280
FCBBF40001420
FCBBF40001730//GUANINE NUCLEOTIDE-BINDING PROTEIN BETA SUBUNIT-LIKE
PROTEIN 12.3 (P205) (RECEPTOR OF ACTIVATED PROTEIN KINASE C 1)
(RACK1).//4.20E-120//265aa//84%//P25388
FCBBF40005480
FEBRA10001880//Homo sapiens serine/threonine kinase mRNA, complete
cds.//4.60E-106//344aa//53%//AF005046
FEBRA10001900
FEBRA20002100//D-XYLOSE-PROTON SYMPORTER (D-XYLOSE
TRANSPORTER).//2.00E-13//159aa//27%//052733
FEBRA20003210
FEBRA20004620//RAP1 GTPASE ACTIVATING PROTEIN 1
(RAP1GAP).//1.50E-46//208aa//43%//P47736
FEBRA20007620//PUTATIVE PRE-mRNA SPLICING FACTOR ATP-DEPENDENT RNA
HELICASE SPBC16H, 5.10; C.//2.30E-126//692aa//39%//042945
FEBRA20009090
FEBRA20010120//CLEAVAGE STIMULATION FACTOR, 64 KDA SUBUNIT (CSTF 64
KDA SUBUNIT) (CF-1 64 KDA
SUBUNIT).//1.10E-73//137aa//97%//P33240
FEBRA20017050
FEBRA20018280
FEBRA20018690//ZINC FINGER PROTEIN 44 (ZINC FINGER PROTEIN KOX7)
(FRAGMENT).//2.00E-08//96aa//34%//P15621
FEBRA20024100//Rattus norvegicus myosin heavy chain Myr 8 mRNA,
complete cds.//0//863aa//78%//AF209114
FEBRA20025270
FEBRA20025520
FEBRA20026110//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//1.10E-217//810aa//48%//Q05481
FEBRA20026280
FEBRA20027810
FEBRA20029860
FEBRA20034360
FEBRA20034680//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//5.60E-93//481aa//35%//P51523
FEBRA20037260
FEBRA20037500
FEBRA20040530//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//3.30E-115//335aa//54%//P51523
FEBRA20042190
FEBRA20052910
FEBRA20060610
FEBRA20072120
FEBRA20079310
FEBRA20080810//Rattus norvegicus mRNA for peptide/histidine
transporter, complete cds.//1.30E-107//239aa//87%//AB000280
FEBRA20082010//ZINC FINGER PROTEIN 195.//0//482aa//99%//014628
FEBRA20082100
FEBRA20086620//NEURONAL OLFACTOMEDIN-RELATED ER LOCALIZED PROTEIN
PRECURSOR (NOEL) (1B426B).//3.80E-165//453aa//65%//Q62609
FEBRA20088360//ALPHA-ADAPTIN C (CLATHRIN ASSEMBLY PROTEIN COMPLEX 2
ALPHA-C LARGE CHAIN) (100 KDA COATED VESICLE PROTEIN C) (PLASMA
MEMBRANE ADAPTOR HA2/AP2 ADAPTIN ALPHA C
SUBUNIT).//5.60E-05//58aa//53%//P17427
FEBRA20090290
FEBRA20092890//Rattus norvegicus neural cell adhesion protein BIG-2
precursor (BIG-2) mRNA, complete cds.//0//697aa//93%//U35371
FEBRA20093520
FEBRA20095140
FEBRA20095880
FEBRA20097310//Human Hsp27 ERE-TATA-binding protein (HET) mRNA,
complete cds.//0//597aa//97%//U72355
FEBRA20098460
FEBRA20111460
FEBRA20113560//R. norvegicus mRNA for DRM
protein.//5.10E-65//157aa//80%//Y10019
FEBRA20125070
FEBRA20130190//UDP-GlcNAc:betaGal
beta-1,3-N-acetylglucosaminyltransferase
3//8.20E-65//345aa//42%//NP.sub.--055071
FEBRA20132740//Homo sapiens mRNA for CDEP, complete
cds.//3.70E-16//40aa//92%//AB008430
FEBRA20140100//RER1 PROTEIN.//3.20E-106//196aa//99%//015258
FEBRA20144170//RIBOSOMAL PROTEIN S6 KINASE II ALPHA 2 (EC 2.7.1.-)
(S6KII-ALPHA 2) (P90-RSK 2) (RIBOSOMAL S6 KINASE 3) (RSK3)
(PP90RSK3).//1.30E-269//495aa//99%//Q15349
FEBRA20145780
FEBRA20161120
FEBRA20166540
FEBRA20167390//Mus musculus ST6GalNAc V mRNA for GD1 alpha
synthase, complete cds.//9.40E-64//134aa//91%//AB030836
FEBRA20171380//ZINC FINGER PROTEIN 33A (ZINC FINGER PROTEIN KOX31)
(KIAA0065) (HA0946) (FRAGMENT).//6.30E-127//415aa//48%//Q06730
FEBRA20174410//Mus musculus mRNA for nuclear protein ZAP, complete
cds.//2.30E-193//543aa//69%//AB033168
FEBRA20176800
FEBRA20184330//Rattus norvegicus glutamate receptor interacting
protein 2 (GRIP2) mRNA, complete
cds.//8.10E-72//161aa//88%//AF072509
FEBRA20192420
FEBRA20195820//ZINC FINGER PROTEIN
132.//2.60E-47//134aa//63%//P52740
FEBRA20196370
FEBRA20196630//RNA helicase-related
protein//0//317aa//100%//NP.sub.--031398
FEBRA20197110
FEBRA20204000
FEBRA20204060
FEBRA20211710
FEBRA20214970
FEBRA20215500//Mus musculus Nulp1 (nulp1) mRNA, complete
cds.//1.80E-38//146aa//64%//U94988
FEBRA20216360
FEBRA20222040
FEBRA20223220//Homo sapiens mRNA for
fibulin-4.//9.20E-110//202aa//100%//AJ132819
FEBRA20225040//high-glucose-regulated protein
8//1.40E-110//514aa//51%//NP.sub.--057342
FEBRA20226010
FEBRA20229560
FEBRA20229630
FEBRA20232850
FEBRA20233770//NEURONAL PAS DOMAIN PROTEIN 2 (NEURONAL PAS2)
(MEMBER OF PAS PROTEIN 4) (MOP4).//6.30E-62//164aa//81%//Q99743
FEBRA20235500//P3 PROTEIN.//5.20E-74//391aa//39%//P09131
FEBRA20237640//Rattus norvegicus neurabin mRNA, complete
cds.//9.10E-29//172aa//46%//U72994
FEHRT20003250//PHOSPHATIDYLINOSITOL 4-KINASE ALPHA (EC 2.7.1.67)
(PI4-KINASE) (PTDINS-4-KINASE)
(PI4K-ALPHA).//2.20E-146//269aa//100%//P42356
FELNG20002410
HCASM10000500//TOPOISOMERASE 1-RELATED PROTEIN
TRF5.//3.70E-09//193aa//22%//P48561
HCHON10001760//histone deacetylase
5//1.00E-133//320aa//67%//NP.sub.--005465
HCHON20000380
HCHON20001560//TRANSCRIPTION FACTOR-LIKE PROTEIN
MORF4.//7.20E-116//235aa//93%//Q9Y690
HCHON20002260
HCHON20003220//10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (EC 1.5.1.6)
(10-FTHFDH) (FBP-CI).//2.30E-302//731aa//72%//P28037
HCHON20003440//Homo sapiens cyclin-D binding Myb-like protein mRNA,
complete cds.//1.30E-64//155aa//87%//AF084530
HCHON20007380//Homo sapiens mRNA for HELG
protein.//3.90E-129//331aa//76%//AJ277291
HCHON20007510//rab6 GTPase activating protein (GAP and
centrosome-associated)//O//765aa//62%//NP.sub.--036329
HCHON20008150
HCHON20008180
HCHON20008320//ZINC FINGER PROTEIN
135.//2.20E-130//345aa//62%//P52742
HCHON20008980
HCHON20009350
HCHON20009560//ZINC FINGER PROTEIN
74.//1.50E-22//113aa//46%//Q16587
HCHON20010990
HCHON20011160
HCHON20014970
HCHON20015230//Homo sapiens nuclear pore-associated protein
(NPAP60L) mRNA, complete cds.//1.40E-78//158aa//97%//AF107840
HCHON20015350//PUTATIVE RRNA METHYLTRANSFERASE SPB1 (EC
2.1.1.-).//1.90E-117//771aa//36%//P25582
HCHON20015980//Homo sapiens integrin alpha 11 subunit precursor
(ITGA11) mRNA, complete cds.//1.00E-227//419aa//99%//AF137378
HCHON20016040//INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3
PRECURSOR (IGFBP-3) (IBP-3) (IGF-BINDING PROTEIN
3).//2.00E-21//45aa//97%//P17936
HCHON20016650//Mus musculus seven-pass transmembrane receptor
precursor (Celsr1) mRNA, complete
cds.//6.20E-27//343aa//27%//AF031572
HCHON20022470
HCHON20035130//ZINC FINGER PROTEIN 22 (ZINC FINGER PROTEIN KOX15)
(FRAGMENT).//1.10E-18//64aa//56%//P17026
HCHON20036420//Homo sapiens mRNA for PED
phosphoprotein.//1.30E-64//130aa//100%//Y13736
HCHON20036760
HCHON20040020//TNF-INDUCIBLE PROTEIN
CG12.sub.--1.//8.80E-40//302aa//36%//095236
HCHON20043590
HCHON20059870//Hypothetical
protein.//4.20E-204//667aa//56%//AL163279
HCHON20064590//ALPHA-2-MACROGLOBULIN PRECURSOR
(ALPHA-2-M).//5.00E-38//654aa//27%//P01023
HCHON20067220
HCHON20067700//Homo sapiens gremlin mRNA, complete
cds.//5.70E-76//106aa//99%//AF045800
HCHON20068410//Drosophila melanogaster microtubule associated
protein (asp) mRNA, complete cds.//8.10E-47//803aa//27%//U95171
HCHON20068710
HCHON20074820
HCHON20076500
HCHON20086720//INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3
PRECURSOR (IGFBP-3) (IBP-3) (IGF-BINDING PROTEIN
3).//4.10E-113//205aa//100%//P17936
HCHON20097490//dedicator of cyto-kinesis
1//1.00E-154//860aa//37%//NP.sub.--001371
HCHON20100740//LACTADHERIN PRECURSOR (MILK FAT GLOBULE-EGF FACTOR
8) (MFG-E8) (HMFG) (BREAST EPITHELIAL ANTIGEN BA46) (MFGM)
[CONTAINS: MEDIN].//1.60E-205//363aa//99%//Q08431
HEART20003060//BASIGIN PRECURSOR (LEUKOCYTE ACTIVATION ANTIGEN M6)
(COLLAGENASE STIMULATORY FACTOR) (EXTRACELLULAR MATRIX
METALLOPROTEINASE INDUCER) (EMMPRIN) (5F7) (CD147
ANTIGEN).//1.30E-132//248aa//100%//P35613
HEART20005410
HEART20017730//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,
NONERYTHROID).//2.40E-25//368aa//30%//Q01484
HEART20021840
HEART20025980//Homo sapiens smoothelin large isoform L2 (SMTN)
mRNA, complete cds.//9.00E-152//223aa//97%//AF064238
HEART20034320//ENDOGLUCANASE Z PRECURSOR (EC 3.2.1.4)
(ENDO-1,4-BETA-GLUCANASE) (THERMOACTIVE CELLULASE) (AVICELASE
I).//1.20E-64//480aa//32%//P23659
HEART20037810
HEART20049400
HEART20049410//Homo sapiens cerberus-related protein (CER1) gene,
complete cds.//1.10E-12//144aa//29%//AF090189
HEART20049800
HEART20061950//Homo sapiens mRNA for
myopodin.//1.30E-28//327aa//35%//AJ010482
HEART20063340
HEART20067870
HEART20067890
HEART20072310
HEART20074430
HEART20077670//Mus musculus mRNA for E-MAP-115
protein.//1.70E-50//363aa//41%//Y15197
HEART20083640//Mus musculus Xin mRNA, complete
cds.//3.10E-63//272aa//58%//AF051945
HEART20089940
HEART20090000//Rattus norvegicus PIPP mRNA for proline-rich
inositol polyphosphate 5-phosphatase, complete
cds.//0//639aa//91%//AB032551
HEART20095990
HHDPC10000650
HHDPC10000830//HYPOTHETICAL 24.9 KDA PROTEIN C16C10.7 IN CHROMOSOME
III.//1.50E-23//56aa//60%//Q09463
HHDPC20001040
HHDPC20006920
HHDPC20014320//ADAM 12 PRECURSOR (EC 3.4.24.-) (A DISINTEGRIN AND
METALLOPROTEINASE DOMAIN 12) (MELTRIN
ALPHA).//1.20E-14//139aa//38%//043184
HHDPC20030490//LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS
FACTOR-ALPHA FACTOR (LPS-INDUCED TNF-ALPHA FACTOR) (P53-INDUCED
PROTEIN 7).//1.90E-69//134aa//95%//Q99732
HHDPC20031130//Kruppel-type zinc finger (C2H2) [Homo
sapiens]//3.30E-196//607aa//57%//NP.sub.--005806
HHDPC20034390
HHDPC20034720//CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4
(INTRACELLULAR CHLORIDE ION CHANNEL PROTEIN
P64H1).//1.50E-121//213aa//99%//Q9Y696
HHDPC20057420//Mus musculus proline-rich protein (Bprp) mRNA,
complete cds.//5.40E-45//143aa//69%//AF085348
HHDPC20057940
HHDPC20064600//SUPPRESSOR PROTEIN
SRP40.//8.00E-05//175aa//24%//P32583
HHDPC20068620//Ig kappa chain precursor V region (0-81VL)-human
(fragment)//8.10E-06//132aa//31%//S22658
HHDPC20084140//Homo sapiens polyadenylate binding
protein-interacting protein-1 (PAIP1) mRNA, complete
cds.//8.10E-12//230aa//23%//AF013758
HHDPC20091140//Homo sapiens gremlin mRNA, complete
cds.//2.20E-60//105aa//100%//AF045800
HHDPC20091780//coagulation factor V (proaccelerin, labile
factor)//2.00E-26//170aa//40%//NP.sub.--000121
HHDPC20092080//INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3
PRECURSOR (IGFBP-3) (IBP-3) (IGF-BINDING PROTEIN
3).//3.30E-100//185aa//94%//P17936
HHDPC20095280
HLUNG10000550
HLUNG20016330//Homo sapiens actin filament associated protein
(AFAP) mRNA, complete cds.//6.70E-130//531aa//49%//AF188700
HLUNG20016770
HLUNG20017120//PEPTIDE CHAIN RELEASE FACTOR 2
(RF-2).//8.40E-11//82aa//40%//Q53915
HLUNG20023340//Mus musculus SLM-1 (Slm1) mRNA, complete
cds.//8.80E-141//270aa//95%//AF098796
HLUNG20033780//Rho guanine nucleotide exchange factor
5//6.00E-60//440aa//38%//NP.sub.--005426
HLUNG20084390
IMR3220002430//CHROMATIN ASSEMBLY FACTOR 1 P48 SUBUNIT (CAF-1 P48
SUBUNIT) (RETINOBLASTOMA BINDING PROTEIN P48)
(RETINOBLASTOMA-BINDING PROTEIN 4) (MSI1 PROTEIN
HOMOLOG).//7.10E-09//303aa//24%//Q09028
KIDNE20002520//glutamyl tRNA synthetase
homolog//9.90E-156//290aa//100%//T00743
[0623] KIDNE20003940//RENAL SODIUM-DEPENDENT PHOSPHATE TRANSPORT
PROTEIN 2 (SODIUM/PHOSPHATE COTRANSPORTER 2) (NA(+)/PI
COTRANSPORTER 2) (RENAL SODIUM-PHOSPHATE TRANSPORT PROTEIN 2)
(RENAL NA+-DEPENDENT PHOSPHATE COTRANSPORTER
2).//1.80E-151//582aa//51%//Q06496
KIDNE20006780
KIDNE20007210//Xenopus laevis mRNA for RPA interacting protein
alpha (ripalpha gene).//8.30E-17//104aa//47%//AJ243177
KIDNE20007770//CARCINOEMBRYONIC ANTIGEN CGM6 PRECURSOR(NONSPECIFIC
CROSS-REACTING ANTIGEN NCA-95) (ANTIGEN CD67) (CD66B
ANTIGEN).//1.20E-17//326aa//27%//P31997
KIDNE20008010//Homo sapiens mRNA for putative protein kinase (WNK1
gene).//2.50E-25//460aa//29%//AJ296290
KIDNE20009470
KIDNE20011170
KIDNE20011400
KIDNE20013730
KIDNE20017130//Oreochromis niloticus sex-determining protein DMO
mRNA, complete cds.//5.10E-43//252aa//43%//AF203490
KIDNE20018730
KIDNE20018970
KIDNE20020150//HEAT SHOCK 70 KDA PROTEIN 1 (HSP70.1)
(HSP70-1/HSP70-2).//9.90E-251//458aa//98%//P08107
KIDNE20021680//SHORT CHAIN 3-HYDROXYACYL-COA DEHYDROGENASE
PRECURSOR (EC 1.1.1.35) (HCDH).//7.10E-141//273aa//98%//Q16836
KIDNE20021910//Homo sapiens MRS1 mRNA, complete
cds.//2.30E-30//339aa//27%//AF093239
KIDNE20021980
KIDNE20022620//like-glycosyltransferase//8.50E-253//633aa//70%//NP.sub.--
-004728
KIDNE20024830//Homo sapiens copine I mRNA, complete
cds.//1.30E-46//134aa//47%//U83246
KIDNE20027250//ZINC FINGER PROTEIN 41 (ZFP-41) (CTFIN92)
(FRAGMENT).//3.80E-55//105aa//91%//Q02526
KIDNE20027950//ZINC FINGER PROTEIN 7 (ZINC FINGER PROTEIN KOX4)
(ZINC FINGER PROTEIN HF.16).//2.40E-40//82aa//100%//P17097
KIDNE20028390//GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (EC
2.7.7.10).//6.00E-70//85aa//90%//P43424
KIDNE20028720//Mus musculus Ac39/physophilin mRNA, complete
cds.//2.70E-130//345aa//68%//U21549
KIDNE20028830
KIDNE20029800
KIDNE20067330
KIDNE20079440
KIDNE20096280
KIDNE20096470
KIDNE20100070//Rattus norvegicus kidney-specific protein (KS) mRNA,
complete cds.//1.20E-253//572aa//77%//AF062389
KIDNE20100840
KIDNE20101370//GOLGIN-95.//3.40E-20//76aa//68%//Q08379
KIDNE20101510//UROMODULIN PRECURSOR (TAMM-HORSFALL URINARY
GLYCOPROTEIN) (THP).//0//519aa//95%//P07911
KIDNE20102650
KIDNE20102710//Mus musculus mRNA for Shank3b protein (shank3
gene).//1.20E-81//203aa//71%//AJ245904
KIDNE20104300
KIDNE20106740
KIDNE20107390//Homo sapiens CHRAC17 (CHRAC17) mRNA, complete
cds.//1.50E-40//105aa//86%//AF226077
KIDNE20107500
KIDNE20107620//Rattus norvegicus protein kinase WNK1 (WNK1) mRNA,
complete cds.//8.70E-140//266aa//74%//AF227741
KIDNE20109730//Mus musculus orphan transporter isoform B9 (Xtrp2)
mRNA, alternatively spliced, complete
cds.//8.70E-34//103aa//65%//AF075266
KIDNE20109890//Rattus norvegicus TGF-beta resistance-associated
protein (TRAG) mRNA, complete
cds.//2.60E-141//774aa//37%//AF305813
KIDNE20112000
KIDNE20115080//Homo sapiens mRNA for hNBL4, complete
cds.//6.20E-115//226aa//96%//AB030240
KIDNE20118580//actin interacting protein [Arabidopsis
thaliana].//5.00E-34//140aa//56%//CAB16815
KIDNE20120090
KIDNE20121880//Mus musculus claudin-19 mRNA, partial
cds.//6.10E-97//193aa//95%//AF249889
KIDNE20122910
KIDNE20124400//Homo sapiens mRNA for ALEX1, complete
cds.//1.10E-18//167aa//28%//AB039670
KIDNE20125630
KIDNE20126010
KIDNE20126130
KIDNE20127100//Drosophila melanogaster Diablo (dbo) mRNA, complete
cds.//1.10E-10//254aa//26%//AF237711
KIDNE20127450
KIDNE20127750//Homo sapiens partial mRNA for transport-secretion
protein 2.1 (TTS-2.1 gene).//6.50E-45//178aa//46%//AJ278475
KIDNE20130450
KIDNE20131580//Homo sapiens mRNA for LAK-4p, complete
cds.//1.80E-111//211aa//100%//AB002405
KIDNE20132180
KIDNE20137340//HYPOTHETICAL 49.1 KDA PROTEIN C11D3.06 IN CHROMOSOME
I.//5.80E-13//149aa//30%//Q10085
KIDNE20138010
KIDNE20141190
KIDNE20144890
KIDNE20148900
KIDNE20163880
KIDNE20180710
KIDNE20181660
KIDNE20182690//Homo sapiens mRNA for RERE, complete
cds.//3.50E-222//401aa//99%//AB036737
KIDNE20186780
KIDNE20190740//Rattus norvegicus SNIP-b mRNA, complete
cds.//6.70E-20//51aa//92%//AF156982
LIVER10001260
LIVER10004790
LIVER20002160//HEAT SHOCK COGNATE 71 KDA
PROTEIN.//0//585aa//95%//P11142
LIVER20011130//Homo sapiens F-box protein FBL9 mRNA, partial
cds.//5.50E-107//210aa//99%//AF176701
LIVER20011910
LIVER20028420
LIVER20035110
LIVER20035680
LIVER20038540
LIVER20045650
LIVER20055200//Homo sapiens leucocyte immunoglobulin-like
receptor-8 (LIR-8) mRNA, complete
cds.//2.50E-43//132aa//71%//AF025534
LIVER20055440//Homo sapiens Rho GAP p190-A mRNA, complete
cds.//2.90E-101//195aa//98%//AF159851
LIVER20059810//UDP-GLUCOSE 4-EPIMERASE (EC 5.1.3.2)
(GALACTOWALDENASE) (UDP-GALACTOSE
4-EPIMERASE).//1.60E-15//39aa//100%//Q14376
LIVER20062510
LIVER20064100//Ciona intestinalis mRNA for myoplasmin-C1, complete
cds.//2.90E-14//167aa//26%//D42167
LIVER20064690//PLASMA SERINE PROTEASE INHIBITOR PRECURSOR (PCI)
(PROTEIN C INHIBITOR) (PLASMINOGEN ACTIVATOR INHIBITOR-3)
(PAI3).//1.70E-146//319aa//89%//P05154
LIVER20075680
LIVER20080530//Drosophila melanogaster forked mRNA for large Forked
protein, complete cds.//1.10E-11//198aa//32%//D21203
LIVER20084730
LIVER20085800
LIVER20087060//Mus musculus putative purine nucleotide binding
protein mRNA, complete cds.//2.70E-233//619aa//70%//U44731
LIVER20087510
LIVER20091180
MAMGL10000830//Drosophila melanogaster L82B (L82) mRNA, complete
cds.//3.00E-27//231aa//38%//AF125385
MESAN10001260//Drosophila melanogaster Crossveinless 2 (CV-2) mRNA,
complete cds.//6.50E-104//628aa//35%//AF288223
MESAN20004570//MEDIAN BODY
PROTEIN.//3.00E-07//343aa//23%//Q08014
MESAN20014500//Drosophila melanogaster Dispatched (dispatched)
mRNA, complete cds.//1.60E-46//225aa//37%//AF200691
MESAN20025190//Mus musculus cell cycle checkpoint control protein
Mrad9 gene, complete cds.//7.30E-19//43aa//97%//AF045662
MESAN20027090
MESAN20029400
MESAN20031900//Homo sapiens mRNA for zinc-binding protein (Rbcc728
gene).//2.90E-161//724aa//43%//AJ272269
MESAN20035290
MESAN20036460
MESAN20038510
MESAN20089360
MESAN20101140//PINCH PROTEIN (PARTICULARY INTERESTING NEW CYS-HIS
PROTEIN).//2.30E-25//52aa//98%//P48059
MESAN20103120//Homo sapiens sodium/calcium exchanger NCKX3
(SLC24A3) mRNA, complete cds.//4.10E-66//289aa//37%//AF169257
MESAN20106640
MESAN20115970
MESAN20121130
MESAN20125860//MELANOTRANSFERRIN PRECURSOR (MELANOMA-ASSOCIATED
ANTIGEN P97).//1.30E-40//81aa//100%//P08582
MESAN20127350//myelin expression
factor-3//2.80E-15//227aa//29%//JE0163
MESAN20130220//Homo sapiens testis-specific chromodomain Y-like
protein (CDYL) mRNA, alternatively processed, complete
cds.//2.10E-126//319aa//63%//AF081258
MESAN20132110
MESAN20136110//Ciona savignyi mRNA for PEM-3, complete
cds.//1.90E-85//236aa//65%//AB001769
MESAN20138450
MESAN20139360
MESAN20141920//Human ovarian cancer downregulated myosin heavy
chain homolog (Doc1) mRNA, complete cds.//0//691aa//97%//U53445
MESAN20152770
MESAN20153910
MESAN20154010//Homo sapiens mRNA for putative
ribulose-5-phosphate-epimerase, partial
cds.//9.10E-60//69aa//100%//AJ224326
MESAN20157080
MESAN20161590
MESAN20164090
MESAN20171520//Homo sapiens TNF intracellular domain-interacting
protein mRNA, complete cds.//9.30E-30//198aa//40%//AF168676
MESAN20174170//REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4)
(RGP4).//1.80E-39//80aa//98%//P49798
MESAN20182090
MESAN20186700
NESOP10001080
NOVAR10000150
NOVAR10000910//COLORECTAL MUTANT CANCER PROTEIN (MCC
PROTEIN).//6.00E-199//392aa//98%//P23508
NOVAR10001020
NOVAR20000380
NOVAR20003520
NT2NE20003740
NT2NE20010050
NT2NE20010210
NT2NE20010400//Homo sapiens GLO13 mRNA, complete
cds.//2.90E-51//223aa//60%//AF267859
NT2NE20010490//ZINC FINGER PROTEIN 85 (ZINC FINGER PROTEIN HPF4)
(HTF1).//1.30E-194//464aa//72%//Q03923
NT2NE20015240
NT2NE20021620//Saccharomyces cerevisiae Vps9p (VPS9) gene, complete
cds.//1.00E-13//250aa//24%//U20373
NT2NE20043780
NT2NE20053580
NT2NE20068130//CELL SURFACE GLYCOPROTEIN 1 PRECURSOR (OUTER LAYER
PROTEIN B) (S-LAYER PROTEIN 1).//2.50E-34//377aa//40%//Q06852
NT2NE20072200
NT2NE20074250
NT2NE20080170//HUNTINGTIN-ASSOCIATED PROTEIN-INTERACTING PROTEIN
(DUO PROTEIN) (KALIRIN) (PAM COOH-TERMINAL INTERACTOR PROTEIN 10)
(P-CIP10).//6.60E-57//661aa//27%//P97924
NT2NE20089610
NT2NE20089970//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//1.60E-29//77aa//81%//Q05481
NT2NE20108540
NT2NE20110360
NT2NE20118960//DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE-PROTEIN
GLYCOSYLTRANSFERASE 63 KDA SUBUNIT PRECURSOR (EC 2.4.1.119)
(RIBOPHORIN II).//9.30E-274//562aa//94%//P04844
NT2NE20122430//GLYOXYLATE-INDUCED
PROTEIN.//7.70E-25//144aa//38%//P30147
NT2NE20124480
NT2NE20125050//Gallus gallus mRNA for avena, complete
cds.//5.80E-199//468aa//84%//AB017437
NT2NE20130190
NT2NE20131890
NT2NE20132170//Rattus norvegicus lysosomal amino acid transporter 1
mRNA, complete cds.//3.70E-97//357aa//52%//AF361239
NT2NE20142210//SINGLE-MINDED HOMOLOG 2 (SIM TRANSCRIPTION FACTOR)
(MSIM).//3.00E-24//660aa//26%//Q61079
NT2NE20146810
NT2NE20152750
NT2NE20155110
NT2NE20156260
NT2NE20157470//COMPLEMENT C2 PRECURSOR (EC 3.4.21.43) (C3/C5
CONVERTASE).//6.60E-138//256aa//100%//P06681
NT2NE20158600//erythroid ankyrin-Synechocystis sp. (strain PCC
6803).//7.00E-13//160aa//31%//S74626
NT2NE20159740
NT2NE20172590
NT2NE20174800
NT2NE20174920
NT2NE20177520//Guinea pig mRNA for decay-accelerating factor
(isoform GDab-SEC), complete cds.//1.70E-15//273aa//28%//D49421
NT2NE20181650//Shb=Src homology 2
protein//2.90E-36//115aa//43%//AAB29780
NT2NE20183760
NT2NE20184900//Mus musculus mRNA for transcription factor CA150b,
complete cds.//8.60E-29//98aa//55%//AB023485
NT2NE20187390
NT2RI20001330//Homo sapiens KE03 protein mRNA, partial
cds.//3.40E-103//339aa//57%//AF064604
NT2RI20003480//GLYPICAN-2 PRECURSOR (CEREBROGLYCAN) (HSPG
M13).//1.80E-261//581aa//82%//P51653
NT2RI20005750//Rattus norvegicus GTP-binding protein REM2 (Rem2)
mRNA, complete cds.//8.90E-139//272aa//95%//AF084464
NT2RI20009870//lunatic fringe precursor [Mus
musculus]//5.50E-123//237aa//91%//U94351
NT2RI20022600
NT2RI20023160
NT2RI20023590
NT2RI20023910//Homo sapiens TMTSP mRNA for transmembrane molecule
with thrombospondin module, complete
cds.//0//480aa//96%//AB044385
NT2RI20025400//Mouse mRNA for P24 protein, complete
cds.//9.70E-94//196aa//91%//D83206
NT2RI20025640
NT2RI20028470
NT2RI20036670
NT2RI20040930//MITOCHONDRIAL CARRIER PROTEIN YMC2
PRECURSOR.//1.10E-27//194aa//38%//P38087
NT2RI20040990//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,
NONERYTHROID).//2.40E-25//368aa//30%//Q01484
NT2RI20041880//MYOSIN HEAVY CHAIN, NONMUSCLE TYPE A (CELLULAR
MYOSIN HEAVY CHAIN, TYPE A)
(NMMHC-A).//8.10E-10//322aa//21%//P35579
NT2RI20046080
NT2RI20048840//GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2
SUBUNIT (ADENYLATE CYCLASE-INHIBITING G ALPHA
PROTEIN).//2.10E-171//316aa//100%//P04899
NT2RI20050960//Homo sapiens p53 regulated PA26-T2 nuclear protein
(PA26) mRNA, complete cds.//5.40E-164//496aa//61%//AF033120
NT2RI20054050//Drosophila melanogaster Abnormal X segregation (Axs)
gene, complete cds.//2.40E-83//487aa//37%//AF101361
NT2RI20055790
NT2RI20056700//NEURONAL OLFACTOMEDIN-RELATED ER LOCALIZED PROTEIN
PRECURSOR (NOEL) (1B426B).//3.40E-237//439aa//97%//Q62609
NT2RI20069730
NT2RI20076290
NT2RI20086220
NT2RI20091730
NT2RI20091940//CORNICHON-LIKE
PROTEIN.//9.70E-73//159aa//81%//035089
NT2RI20198260
NT2R1 20203900
NT2RI20207030
NT2RI20216250
NT2RI20240080//SMALL GLUTAMINE-RICH TETRATRICOPEPTIDE
REPEAT-CONTAINING PROTEIN.//1.30E-86//311aa//58%//043765
NT2R120244600//Homo sapiens mRNA for sphingosine-1-phosphatase
(ORF1).//2.60E-50//273aa//36%//AJ293294
NT2RI20244960
NT2RI20250750
NT2RI20252550
NT2RI20273230//PUTATIVE HELICASE
YGR271W.//1.10E-14//152aa//38%//P53327
NT2RP60000770//Homo sapiens mRNA for ZAC zinc finger
protein.//5.80E-179//325aa//98%//AJ006354
NT2RP60000850//Bos taurus RPGR-interacting protein-1 (RPGRIP1)
mRNA, complete cds.//2.10E-139//751aa//38%//AF227258
NT2RP70010740
NT2RP70027380//N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN)
(A-CHIMAERIN).//7.40E-31//203aa//36%//P15882
NT2RP70032610//ALPHA ENOLASE (EC 4.2.1.11) (2-PHOSPHO-D-GLYCERATE
HYDRO-LYASE) (NON-NEURAL ENOLASE) (NNE) (PHOSPHOPYRUVATE
HYDRATASE).//4.40E-180//387aa//88%//P06733
NT2RP70036880//Gtpase activating protein for Ypt1p; Gyp1p
[Saccharomyce
scerevisiae].//2.00E-66//250aa//50%//NP.sub.--014713
NT2RP70037240//H. sapiens E-MAP-115
mRNA.//1.10E-79//475aa//41%//X73882
NT2RP70043480//ZINC FINGER PROTEIN 93 (ZINC FINGER PROTEIN HTF34)
(FRAGMENT).//0//588aa//91%//P35789
NT2RP70044280//CTD-BINDING SR-LIKE PROTEIN RA4
(FRAGMENT).//1.20E-11//190aa//31%//095104
NT2RP70045590//PUTATIVE ENDONUCLEASE C1F12.06C (EC
3.1.-.-).//3.60E-34//246aa//36%//Q10348
NT2RP70056750
NT2RP70062230//NEUROFILAMENT TRIPLET H PROTEIN (200 KDA
NEUROFILAMENT PROTEIN) (NF-H).//2.50E-29//622aa//29%//P19246
NT2RP70063950//PUTATIVE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE
FACTOR(RHO/RAC GEF) (FACIOGENITAL DYSPLASIA PROTEIN
HOMOLOG).//4.90E-13//417aa//26%//P52734
NT2RP70072690
NT2RP70075240
NT2RP70077660
NT2RP70078420//Drosophila melanogaster Centaurin Gamma 1A (ceng1A)
mRNA, complete cds.//1.00E-120//700aa//40%//AF254741
NT2RP70080850
NT2RP70081610//Mus musculus 101F6 protein mRNA, complete
cds.//5.20E-52//214aa//50%//AF131206
NT2RP70085440
NT2RP70102350//Mus musculus mRNA for Olig3 bHLH protein, complete
cds.//1.90E-134//257aa//98%//AB038698
NT2RP70105210
NT2RP70110860
NT2RP70111320
NT2RP70122910
NT2RP70125160
NT2RP70130020
NT2RP70133740//SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN
2.//2.60E-136//267aa//94%//015127
NT2RP70134990
NT2RP70137290
NT2RP70137640
NT2RP70143480
NT2RP70147210
NT2RP70150800
NT2RP70157890//zinc finger protein 267; zinc finger
(C.sub.2H.sub.2) [Homo
sapiens]//1.60E-125//228aa//99%//NP.sub.--003405
NT2RP70159960//Rattus norvegicus p135 SynGAP mRNA, partial
cds.//4.80E-60//177aa//69%//AF053938
NT2RP70169110
NT2RP70175670
NT2RP70179710
NT2RP70181970
NT2RP70188020
NT2RP70188710
NT2RP70190640
NT2RP70192730//LYSOSOMAL ACID LIPASE/CHOLESTERYL ESTER HYDROLASE
PRECURSOR (EC 3.1.1.13) (LAL) (ACID CHOLESTERYL ESTER HYDROLASE)
(STEROL ESTERASE) (LIPASE A) (CHOLESTERYL
ESTERASE).//3.00E-181//323aa//99%//P38571
NT2RP70194450
NT2RP70195430//PUTATIVE NADP-DEPENDENT OXIDOREDUCTASE IN TEHB-RHSE
INTERGENIC REGION (EC 1.-.-.-).//1.10E-57//349aa//38%//P76113
NT2RP70198350//HEPATOMA-DERIVED GROWTH FACTOR
(HDGF).//2.60E-111//213aa//98%//P51858
NT2RP70203790
NTONG20009770//NEUROLYSIN PRECURSOR (EC 3.4.24.16) (NEUROTENSIN
ENDOPEPTIDASE) (MITOCHONDRIAL OLIGOPEPTIDASE M) (MICROSOMAL
ENDOPEPTIDASE) (MEP).//1.30E-304//599aa//92%//P42675
NTONG20013620//Homo sapiens hydroxysteroid sulfotransferase
SULT2B1b (HSST2) mRNA, complete
cds.//9.10E-82//151aa//100%//U92315
NTONG20015870//KERATIN, TYPE II CYTOSKELETAL 4 (CYTOKERATIN 4) (K4)
(CK4).//3.30E-132//489aa//54%//P19013
NTONG20028070//CYR61 PROTEIN PRECURSOR (GIG1 PROTEIN) (INSULIN-LIKE
GROWTH FACTOR-BINDING PROTEIN
10).//1.60E-65//133aa//92%//000622
NTONG20029480//Mus musculus Xin mRNA, complete
cds.//7.20E-93//409aa//54%//AF051945
NTONG20029700//Homo sapiens laminin alpha 3b chain mRNA, partial
cds.//6.60E-230//425aa//92%//AF005258
NTONG20046140//Homo sapiens mRNA for. MNK1, complete
cds.//5.70E-89//177aa//98%//AB000409
NTONG20048060
NTONG20049910
NTONG20050620
NTONG20050860
NTONG20051530//KUPFFER CELL
RECEPTOR.//6.30E-85//391aa//45%//P70194
NTONG20052650//Gallus gallus Xin mRNA, complete
cds.//5.40E-146//768aa//40%//AF051944
NTONG20056570//CORONIN-LIKE PROTEIN
P57.//2.20E-121//356aa//62%//Q92176
NTONG20061870
NTONG20063010//Mus musculus EF-9 mRNA, partial
cds.//1.70E-78//154aa//92%//U72678
NTONG20064400//REPETIN.//2.20E-107//446aa//50%//P97347
NTONG20064840//Mus musculus slp1 mRNA for synaptotagmin-like
protein 1, complete cds.//2.60E-128//258aa//90%//AB050741
NTONG20065010
NTONG20066460//Mus musculus Gd mRNA for gasdermin, complete
cds.//8.30E-207//446aa//88%//AB033595
NTONG20067090//Mus musculus mRNA for Sh3y11, complete
cds.//2.00E-63//136aa//91%//D85926
NTONG20067830//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R)
(ANKYRINS 2.1 AND 2.2).//1.10E-24//227aa//34%//P16157
NTONG20070200//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN
HPF1).//1.30E-134//352aa//65%//P51522
NTONG20070340//collagen alpha 1(IX)
chain//1.50E-43//220aa//45%//S42617
NTONG20075220//Rattus norvegicus SNIP-a mRNA, complete
cds.//1.80E-121//436aa//41%//AF156981
NTONG20076930//ALPHA-1-INHIBITOR III
PRECURSOR.//1.20E-124//513aa//47%//P14046
NTONG20077560
NTONG20083650
NTONG20088620//Homo sapiens genethonin 3 mRNA, partial
cds.//4.90E-202//390aa//99%//AF177292
NTONG20090600//SYNAPSIN I (BRAIN PROTEIN
4.1).//2.10E-07//198aa//29%//P17600
NTONG20090680
NTONG20092290
NTONG20092330//BESTROPHIN (VITELLIFORM MACULAR DYSTROPHY PROTEIN)
(TU15B).//1.40E-135//414aa//59%//076090
OCBBF10000540//Mus musculus rjs (rjs) mRNA, complete
cds.//4.00E-14//105aa//36%//AF061529
OCBBF10001750//Mus musculus mRNA for sprouty-4, complete
cds.//1.50E-159//300aa//92%//AB019280
OCBBF10001850//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//8.90E-166//605aa//51%//P51523
OCBBF20005230
OCBBF20006770//TREACLE PROTEIN (TREACHER COLLINS SYNDROME
PROTEIN).//2.50E-287//693aa//84%//Q13428
OCBBF20013890
OCBBF20019380//seizure related gene
6//6.00E-170//336aa//90%//NP.sub.--067261
OCBBF20019830
OCBBF20020150
OCBBF20020830//Homo sapiens Pumilio 1 (PUMH1) mRNA, complete
cds.//0//814aa//99%//AF315592
OCBBF20022900//Homo sapiens SCHIP-1 mRNA, complete
cds.//2.80E-250//469aa//99%//AF145713
OCBBF20023570
OCBBF20026630
OCBBF20028050//Homo sapiens B2 gene partial cDNA, clone
B2E.//7.70E-38//246aa//33%//AJ002220
OCBBF20028650//DOSAGE COMPENSATION REGULATOR (MALE-LESS PROTEIN)
(NO ACTION POTENTIAL PROTEIN).//1.40E-50//160aa//47%//P24785
OCBBF20029800
OCBBF20030280//Rattus norvegicus hfb2 mRNA, complete
cds.//5.20E-63//175aa//68%//AF031483
OCBBF20030910//PUROMYCIN-SENSITIVE AMINOPEPTIDASE (EC 3.4.11.-)
(PSA).//2.90E-146//279aa//98%//P55786
OCBBF20032460
OCBBF20035930//BETA-SOLUBLE NSF ATTACHMENT PROTEIN
(SNAP-BETA).//7.80E-135//264aa//96%//P81126
OCBBF20037440//ZINC-FINGER PROTEIN HT2A (72 KDA TAT-INTERACTING
PROTEIN).//2.10E-08//80aa//40%//Q13049
OCBBF20039250//Homo sapiens breast cancer metastasis-suppressor 1
(BRMS1) mRNA, complete cds.//2.20E-55//188aa//56%//AF159141
OCBBF20041680
OCBBF20045330
OCBBF20046120//zinc finger protein 16 (KOX
9)//1.00E-131//350aa//59%//NP.sub.--008889
OCBBF20046470//ARFAPTIN 1.//5.80E-114//229aa//97%//P53367
OCBBF20046690//PROBABLE CATION-TRANSPORTING ATPASE WO8D2.5 IN
CHROMOSOME IV (EC 3.6.1.-).//4.20E-105//249aa//39%//Q27533
OCBBF20047570
OCBBF20048660
OCBBF20049300//ZINC FINGER PROTEIN 184
(FRAGMENT).//7.10E-141//566aa//45%//Q99676
OCBBF20049840//Homo sapiens mRNA for neurabin II
protein.//4.90E-166//808aa//47%//AJ401189
OCBBF20050770//CARNITINE O-PALMITOYLTRANSFERASE I, MITOCHONDRIAL
LIVER ISOFORM (EC 2.3.1.21) (CPT I)
(CPTI-L).//3.10E-211//653aa//56%//P32198
OCBBF20051610
OCBBF20053430//Mus musculus MAST205 protein kinase mRNA, complete
cds.//0//498aa//94%//U02313
OCBBF20053490//MANNOSE-6-PHOSPHATE ISOMERASE (EC 5.3.1.8)
(PHOSPHOMANNOSE ISOMERASE) (PMI)
(PHOSPHOHEXOMUTASE).//1.10E-24//52aa//100%//P34949
OCBBF20053730//85 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 (EC
3.1.1.4) (IPLA2) (CAI-PLA2).//0//636aa//91%//060733
OCBBF20054200//DEVELOPMENTAL PROTEIN SEVEN IN
ABSENTIA.//1.10E-27//97aa//54%//P21461
OCBBF20054760//SERINE/THREONINE PROTEIN KINASE RIP (EC 2.7.1.-)
(CELL DEATH PROTEIN RIP) (RECEPTOR INTERACTING
PROTEIN).//4.00E-122//230aa//97%//Q13546
OCBBF20059560//Homo sapiens (clone D320) C219-reactive peptide
mRNA, partial cds.//6.70E-39//140aa//62%//L34688
OCBBF20060300
OCBBF20061720
OCBBF20062140
OCBBF20062410
OCBBF20063320
OCBBF20066390//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//8.90E-63//173aa//65%//P51523
OCBBF20068490//Mus musculus RW1 protein mRNA, complete
cds.//4.60E-40//310aa//37%//AF060565
OCBBF20071210//M-PHASE PHOSPHOPROTEIN 9
(FRAGMENT).//1.80E-96//184aa//100%//Q99550
OCBBF20071840//ZINC FINGER PROTEIN
135.//1.00E-139//416aa//57%//P52742
OCBBF20071960//Coturnix coturnix japonica qMEF2D
gene.//6.50E-06//124aa//31%//AJ002238
OCBBF20072240//Homo sapiens candidate tumor suppressor protein
DICE1 mRNA, complete cds.//7.60E-165//354aa//83%//AF097645
OCBBF20072320
OCBBF20073540//Homo sapiens p30 DBC mRNA, complete
cds.//4.00E-65//146aa//91%//AF293335
OCBBF20074140
OCBBF20076220
OCBBF20078920//Homo sapiens zinc-finger helicase (hZFH)
mRNA,-complete cds.//3.10E-67//152aa//92%//U91543
OCBBF20079310
OCBBF20079460
OCBBF20080050//RTOA PROTEIN
(RATIO-A).//3.50E-07//191aa//32%//P54681
OCBBF20080410//ZINC FINGER PROTEIN 43 (ZINC PROTEIN
HTF6).//6.90E-145//445aa//51%//P28160
OCBBF20081380
OCBBF20082830//NDRG1 PROTEIN (DIFFERENTIATION-RELATED GENE 1
PROTEIN) (DRG1) (REDUCING AGENTS AND TUNICAMYCIN-RESPONSIVE
PROTEIN) (RTP) (NICKEL-SPECIFIC INDUCTION PROTEIN
CAP43).//3.10E-190//282aa//99%//Q92597
OCBBF20084660
OCBBF20085200
OCBBF20086400//Mus musculus ADP-ribosylation factor-like
membrane-associated protein (Arm1) mRNA, complete
cds.//2.10E-114//244aa//87%//AF205936
OCBBF20086910//Mus musculus mSox5L mRNA, complete
cds.//9.30E-253//528aa//91%//AB006330
OCBBF20087010
OCBBF20088140
OCBBF20088220
OCBBF20091150
OCBBF20094240
OCBBF20097720
OCBBF20100400
OCBBF20103130
OCBBF20104040
OCBBF20105570
OCBBF20107090//Homo sapiens protocadherin 68 (PCH68) mRNA, complete
cds.//2.60E-77//359aa//49%//AF029343
OCBBF20107920
OCBBF20108190//ZINC FINGER PROTEIN ZFP-36
(FRAGMENT).//2.90E-151//429aa//61%//P16415
OCBBF20108430//GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-2
SUBUNIT (ADENYLATE CYCLASE-INHIBITING G ALPHA
PROTEIN).//2.10E-171//316aa//100%//P04899
OCBBF20108580//APICAL-LIKE PROTEIN (APXL
PROTEIN).//1.00E-196//376aa//100%//Q13796
OCBBF20108630//ATP-BINDING CASSETTE, SUB-FAMILY A, MEMBER 1
(ATP-BINDING CASSETTE TRANSPORTER 1) (ATP-BINDING CASSETTE
1).//1.00E-63//268aa//46%//P41233
OCBBF20109310
OCBBF20111770
OCBBF20116850//Mus musculus Islr(immunoglobulin superfamily
containing leucine-rich repeat) mRNA, complete
cds.//2.10E-88//285aa//57%//AB024538
OCBBF20118970
OCBBF20120390//SODIUM-DEPENDENT PROLINE TRANSPORTER
(FRAGMENT).//0//636aa//100%//Q99884
OCBBF20121390//RING CANAL PROTEIN (KELCH
PROTEIN).//7.80E-28//220aa//31%//Q04652
OCBBF20122620
OCBBF20124360//Homo sapiens mRNA for Misshapen/NIK-related kinase
MINK-1, complete cds.//2.70E-98//185aa//100%//AB035698
OCBBF20125530//Mus musculus PRAJA1 (Praja1) mRNA, complete
cds.//3.60E-110//281aa//77%//U06944
OCBBF20126780
OCBBF20127040//Drosophila melanogaster woc gene, exons
1-11.//1.10E-09//284aa//24%//AJ276394
OCBBF20127140//GUANINE NUCLEOTIDE-BINDING PROTEIN G(I)/G(S)/G(T)
BETA SUBUNIT 1 (TRANSDUCIN BETA CHAIN
1).//5.50E-63//119aa//100%//P04901
OCBBF20127550
OCBBF20128120//Mus musculus mmDNAJA4 mRNA for mmDj4, complete
cds.//1.20E-205//397aa//93%//AB032401
OCBBF20129360//1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1)
(PHOSPHOLIPASE C-DELTA-1)
(PLC-III).//1.00E-130//461aa//36%//P51178
OCBBF20130110
OCBBF20130910
OCBBF20132850//Homo sapiens brain tumor associated protein NAG14
(NAG14) mRNA, complete cds.//3.80E-24//399aa//27%//AF196976
OCBBF20139260
OCBBF20140640
OCBBF20140890
OCBBF20145760//GLYPICAN-1
PRECURSOR.//3.40E-118//222aa//100%//P35052
OCBBF20148280//Mus musculus mlt 1 gene, complete
cds.//1.70E-151//502aa//63%//AB032418
OCBBF20148730//RING CANAL PROTEIN (KELCH
PROTEIN).//2.90E-43//509aa//26%//Q04652
OCBBF20149280//Mus musculus WAVE-1 mRNA, complete
cds.//4.30E-07//210aa//29%//AF290877
OCBBF20151150
OCBBF20153340//Rattus norvegicus cytosolic sorting protein PACS-1a
(PACS-1) mRNA, complete cds.//0//701aa//93%//AF076183
OCBBF20153350//G PROTEIN PATHWAY SUPPRESSOR 2 (GPS2
PROTEIN).//1.20E-49//103aa//99%//Q13227
OCBBF20155060//CADHERIN-RELATED TUMOR SUPPRESSOR PRECURSOR (FAT
PROTEIN).//1.90E-67//307aa//37%//P33450
OCBBF20164050
OCBBF20164670
OCBBF20170690
OCBBF20173060
OCBBF20173250
OCBBF20173980//Homo sapiens RCC1-like G exchanging factor RLG mRNA,
complete cds.//3.70E-211//531aa//70%//AF060219
OCBBF20178150//Plasmodium falciparum ADA2-like protein gene,
partial cds.//2.20E-19//322aa//27%//AF184590
OCBBF20178880//1'-CIS RETINOL DEHYDROGENASE (EC 1.1.1.105) (11-CIS
RDH).//3.90E-37//101aa//78%//Q92781
OCBBF20178990
OCBBF20180120//Hbmo sapiens sodium-dependent high-affinity
dicarboxylate transporter (NADC3) mRNA, complete
cds.//1.50E-272//320aa//89%//AF154121
OCBBF20180840
OCBBF20186870
OCBBF20188730
OCBBF20189560 PANCR10000910//ATP-binding cassette, sub-family A
member 8//2.00E-17//230aa//30%//NP.sub.--009099
PEBLM10000240
PEBLM10000710//leptin receptor//2.10E-29//69aa//91%//U66496
PEBLM20013120//Homo sapiens rhotekin mRNA, partial
cds.//4.10E-25//164aa//36%//AF290512
PEBLM20024320//zinc resistance protein
homolog//3.80E-28//139aa//45%//T27544
PEBLM20024550
PEBLM20040150
PEBLM20042900
PEBLM20044520//PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT
PAN2 (EC 3.1.13.4) (PAB1P-DEPENDENT
POLY(A)-NUCLEASE).//2.40E-54//331aa//39%//P53010
PEBLM20052820//PROTEIN PHOSPHATASE 2C HOMOLOG 3 (EC 3.1.3.16)
(PP2C-3).//7.60E-09//96aa//36%//Q09173
PEBLM20060310
PEBLM20060360//ZINC FINGER PROTEIN 33A (ZINC FINGER PROTEIN KOX31)
(KIAA0065) (HA0946) (FRAGMENT).//5.10E-12//57aa//56%//Q06730
PEBLM20060490//polymerase (RNA) III (DNA directed) (39 kD) [Homo
sapiens]//1.50E-72//143aa//100%//NP.sub.--006457
PEBLM20071880
PEBLM20072960
PEBLM20074370
PEBLM20075980//Mus musculus immunoglobulin scavenger receptor IgSR
mRNA, complete cds.//2.30E-69//285aa//52%//AF302046
PEBLM20078320//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//2.00E-184//543aa//59%//P51523
PEBLM20085760//Homo sapiens mRNA for TOLLIP
protein.//1.10E-106//153aa//98%//AJ242972
PERIC10000250//DNA TOPOISOMERASE III BETA-1 (EC
5.99.1.2).//1.20E-138//271aa//94%//095985
PERIC20002140
PERIC20003860
PERIC20003870//Mus musculus transcriptional activator alpha-NAC
(Naca) gene, complete cds.//1.20E-152//956aa//43%//U48363
PERIC20004220
PERIC20004780//Rattus norvegicus Jun dimerization protein 1 (jdp-1)
gene, complete cds.//2.00E-15//73aa//49%//U53450
PLACE50000660//PROTEIN ARGININE N-METHYLTRANSFERASE 1 (EC
2.1.1.-).//1.60E-12//200aa//27%//Q63009
PLACE60003480//Rattus norvegicus protein associating with small
stress protein PASS1 (Pass1) mRNA, complete
cds.//4.60E-119//255aa//82%//AF168362
PLACE60004630
PLACE60060420//60S RIBOSOMAL PROTEIN L44
(L36A).//1.70E-29//58aa//100%//P09896
PLACE60079250//Homo sapiens mRNA for actin binding protein ABP620,
complete cds.//0//979aa//61%//AB029290
PLACE60086400
PLACE60119750
PLACE60121080
PLACE60136500
PLACE60136720
PLACE60138830
PLACE60153220
PLACE60155130
PLACE60161600
PLACE60169420
PLACE60177140//PROSTACYCLIN RECEPTOR (PROSTANOID IP RECEPTOR) (PGI
RECEPTOR).//9.90E-135//257aa//99%//P43119
PLACE60181070
PLACE60187690
PLACE60188340
PROST10003220//HOMEOBOX PROTEIN
HOX-A2.//5.00E-69//139aa//95%//043364
PROST10004800
PROST20005050
PROST20005670
PROST20021010
PROST20024890
PROST20029270
PROST20047270
PROST20047390//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//5.70E-52//427aa//31%//P51523
PROST20050670
PROST20052280
PROST20057930
PROST20059040
PROST20066880//Mus musculus zinc finger protein 276 C2H2 type
(Zfp276) mRNA, complete cds.//9.80E-101//192aa//94%//AF178935
PROST20079500
PROST20083600//Bos taurus pyruvate dehydrogenase phosphatase
regulatory subunit precursor, mRNA, complete
cds.//1.40E-101//243aa//83%//AF026954
PROST20087700
PROST20097950
PROST20100460//Homo sapiens secretory mucin MUC6 (MUC6) mRNA,
partial cds.//3.10E-216//421aa//98%//U97698
PROST20104000//SPLICEOSOME ASSOCIATED PROTEIN 62 (SAP 62)
(SF3A66).//1.40E-20//128aa//39%//Q62203
PROST20107820//Human C3f mRNA, complete
cds.//9.90E-140//252aa//100%//U72515
PROST20111050
PROST20112970
PROST20114390
PROST20116600
PROST20120050
PROST20120160
PROST20121900
PROST20123530
PROST20127400
PROST20127800
PROST20130530
PROST20132600
PROST20133270
PROST20144220
PROST20146010
PROST20149160
PROST20149250
PROST20151240
PROST20152460
PROST20153320
PROST20159240//Homo sapiens Opa-interacting protein OIP2 mRNA,
partial cds.//1.10E-19//46aa//100%//AF025438
PROST20161950//Mus musculus RalGDS-like protein 3 mRNA, complete
cds.//8.30E-88//205aa//85%//AF237669
PROST20164440
PROST20166680
PROST20168290
PROST20169800//CYTOCHROME P450 4F2 (EC 1.14.13.30) (CYPIVF2)
(LEUKOTRIENE-B4 OMEGA-HYDROXYLASE) (LEUKOTRIENE-B4
20-MONOOXYGENASE) (CYTOCHROME
P450-LTB-OMEGA).//6.30E-188//507aa//66%//P78329
PROST20170980
PROST20171280//hematopoietic zinc
finger//2.00E-70//380aa//50%//NP.sub.--038894
PROST20175290
PROST20176170//Homo sapiens ENIGMA protein mRNA, complete
cds.//2.60E-156//270aa//98%//AF265209
PROST20178360
PROST20185830//NITROGEN REGULATORY PROTEIN
AREA.//5.50E-07//141aa//28%//013412
PROST20189770//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//5.00E-155//459aa//53%//P51523
PROST20191640//Mus musculus UbcM4-interacting protein 4 mRNA,
complete cds.//1.50E-91//279aa//57%//AF360998
PUAEN10000850
PUAEN20003740
PUAEN20011880//Mus musculus mRNA for MIWI (piwi), complete
cds.//2.70E-190//670aa//51%//AB032604
PUAEN20015260//Rattus norvegicus inositol polyphosphate multikinase
(Ipmk) mRNA, complete cds.//2.40E-111//246aa//85%//AY014898
PUAEN20015860//Mus musculus PDZ-RGS3 protein mRNA, complete
cds.//1.50E-205//469aa//82%//AF350047
PUAEN20018820//C-ETS-2 PROTEIN.//7.90E-261//469aa//99%//P15036
PUAEN20025680
PUAEN20027580
PUAEN20030180//CARBONIC ANHYDRASE XII PRECURSOR (EC 4.2.1.1)
(CARBONATE DEHYDRATASE XII) (CA-XII) (TUMOR ANTIGEN
HOM-RCC-3.1.3).//7.60E-148//259aa//95%//043570
PUAEN20040670//Mus musculus neuronal protein 4.1 mRNA, complete
cds.//0//733aa//93%//AF061283
PUAEN20044000
PUAEN20045110
PUAEN20045250
PUAEN20051100//Mus musculus otogelin mRNA, complete
cds.//2.60E-89//368aa//43%//U96411
PUAEN20052470
PUAEN20055020//Homo sapiens goodpasture antigen-binding protein
(COL4A3BP) mRNA, complete cds.//0//624aa//1.00%//AF136450
PUAEN20078980//faciogenital dysplasia
homolog//1.00E-19//200aa//39%//NP.sub.--032027
PUAEN20081230
PUAEN20083140//Homo sapiens SWAP-70 mRNA, complete
cds.//2.70E-280//451aa//99%//AF210818
PUAEN20085150
PUAEN20108240//Drosophila melanogaster ankyrin 2 (Ank2) mRNA,
complete cds.//5.00E-22//200aa//35%//AF190635
RECTM10001410
RECTM20003490
RECTM20005100
SALGL10001710//Homo sapiens mRNA for C110RF25
gene.//1.80E-88//455aa//41%//AJ300461
SKMUS20001980//Mus musculus N-RAP mRNA, complete
cds.//1.40E-63//141aa//88%//U76618
SKMUS20003610//PUTATIVE MITOCHONDRIAL CARRIER PROTEIN
PET8.//7.40E-59//274aa//47%//P38921
SKMUS20007010//VESTIGIAL PROTEIN.//2.70E-14//209aa//32%//Q26366
SKMUS20007800//PROSTAGLANDIN TRANSPORTER (PGT) (MATRIN
F/G).//4.20E-47//274aa//36%//Q00910
SKMUS20011640
SKMUS20012010
SKMUS20016220//Mus musculus N-RAP mRNA, complete
cds.//1.80E-85//352aa//47%//U76618
SKMUS20018230//Homo sapiens MYPT2 mRNA, complete
cds.//8.10E-13//107aa//40%//AB003062
SKMUS20018500//Homo sapiens t(3;5)(q25.1;p34) fusion gene NPM-MLF1
mRNA, complete cds.//2.30E-131//268aa//94%//L49054
SKMUS20020840
SKMUS20021530//Homo sapiens SPG protein (SPG) mRNA, complete
cds.//1.50E-278//506aa//99%//AF302154
SKMUS20024750//RAS SUPPRESSOR PROTEIN 1 (RSU-1) (RSP-1 PROTEIN)
(RSP-1).//3.90E-21//203aa//33%//Q15404
SKMUS20028210
SKMUS20028400//Mus musculus YIP1B (Yip1b) mRNA, complete
cds.//2.90E-53//142aa//74%//AF217188
SKMUS20029200//Homo sapiens ASB-1 protein mRNA, complete
cds.//1.20E-45//302aa//39%//AF156777
SKMUS20031680
SKMUS20046670
SKMUS20048970//ACTIN, ALPHA SKELETAL MUSCLE (ALPHA-ACTIN
1).//8.00E-181//263aa//99%//P02568
SKMUS20049030//H. sapiens mRNA for
nebulin.//3.50E-148//286aa//99%//X83957
SKMUS20077400
SKMUS20084740
SKNMC20006220
SKNSH20008190//ZINC FINGER PROTEIN
133.//2.80E-165//503aa//56%//P52736
SKNSH20020540
SKNSH20028660
SKNSH20031740
SKNSH20034660
SKNSH20051940
SKNSH20062340
SKNSH20063040//Homo sapiens tetraspan NET-4 mRNA, complete
cds.//1.00E-20//177aa//41%//AF065389
SKNSH20080430
SKNSH20087770
SKNSH20089400//Homo sapiens Rad51-interacting protein mRNA,
complete-cds.//2.20E-172//292aa//93%//AF006259
SKNSH20091970
SMINT20001760//ZINC FINGER PROTEIN 83 (ZINC FINGER PROTEIN
HPF1).//1.40E-37//138aa//37%//P51522
SMINT20005410
SMINT20008240
SMINT20009840//IG KAPPA CHAIN V-II REGION GM607 PRECURSOR
(FRAGMENT).//9.00E-54//117aa//90%//P06309
SMINT20011140
SMINT20011580
SMINT20011990
SMINT20013480
SMINT20014580
SMINT20015590
SMINT20022020
SMINT20023280
SMINT20024570//tektin A1//6.90E-26//124aa//45%//M97188
SMINT20026890//SMOOTHELIN.//3.10E-278//611aa//88%//P53814
SMINT20028820//Homo sapiens mRNA for F5-2, complete
cds.//2.40E-83//162aa//98%//AB020739
SMINT20029760
SMINT20033170
SMINT20033400
SMINT20035690
SMINT20040860
SMINT20042990
SMINT20047810
SMINT20049090//Homo sapiens mRNA for partial putative
mitogen-activated protein kinase kinase
kinase.//2.20E-32//69aa//98%//AJ242724
SMINT20050750//SPARC PRECURSOR (SECRETED PROTEIN ACIDIC AND RICH IN
CYSTEINE) (OSTEONECTIN) (ON) (BASEMENT MEMBRANE PROTEIN
BM-40).//4.20E-111//259aa//82%//P09486
SMINT20051610//Mus musculus ES18 mRNA, complete
cds.//6.90E-235//485aa//88%//AF083929
SMINT20053300//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.//7.00E-20//44aa//100%//AF218421
SMINT20053870
SMINT20056210
SMINT20058000
SMINT20060780
SMINT20065960
SMINT20068010
SMINT20071400
SMINT20073650//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
SMINT20076470
SMINT20080540
SMINT20089170
SMINT20092330
SMINT20092720
SMINT20095050
SMINT20098320
SMINT20100680
SMINT20101440//Human cisplatin resistance associated alpha protein
(hCRA alpha) mRNA, complete cds.//1.70E-96//182aa//100%//U78556
SMINT20102780//NICOTINATE PHOSPHORIBOSYLTRANSFERASE (EC 2.4.2.11)
(NAPRTASE).//5.30E-05//123aa//33%//P18133
SMINT20103690
SMINT20105000
SMINT20105330//BETA-GALACTOSIDASE PRECURSOR (EC 3.2.1.23) (LACTASE)
(ACID BETA-GALACTOSIDASE).//1.00E-54//138aa//78%//P16278
SMINT20106290//FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (EC 3.2.2.23)
(FAPY-DNA GLYCOSYLASE).//7.00E-07//214aa//32%//050606
SMINT20106720//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//3.30E-235//477aa//89%//Y14737
SMINT20108530
SMINT20109970
SMINT20110330
SMINT20110660//Homo sapiens mammalian inositol hexakisphosphate
kinase 2 (IP6K2) mRNA, complete
cds.//1.20E-33//68aa//100%//AF177145
SMINT20112730//IG ALPHA-1 CHAIN C
REGION.//1.70E-196//353aa//99%//P01876
SMINT20115880//Kruppe1 associated box (KRAB) zinc finger 1 [Rattus
norvegicus]//1.50E-42//211aa//45%//NP.sub.--062566
SMINT20121220//MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B (CELLULAR
MYOSIN HEAVY CHAIN, TYPE B)
(NMMHC-B).//1.00E-18//493aa//24%//P35580
SMINT20121950//HYPOTHETICAL 70.2 KDA PROTEIN C22E12.10C IN
CHROMOSOME I.//5.70E-16//90aa//45%//Q10361
SMINT20122850
SMINT20122910//Mus musculus StAR-related protein 1-4E mRNA, partial
cds.//1.50E-77//170aa//82%//AY007808
SMINT20127350//U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA (U1 SNRNP
70 KDA) (SNRP70).//3.50E-14//186aa//32%//P08621
SMINT20127930//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
SMINT20130320//Rattus norvegicus MHC class II transactivator type
IV (CIITA) mRNA, complete cds.//2.50E-33//645aa//26%//AF251307
SMINT20131810
SMINT20132280
SMINT20136130//IG LAMBDA CHAIN C
REGIONS.//4.00E-51//105aa//95%//P01842
SMINT20138900//DESMIN.//7.20E-203//425aa//94%//P17661
SMINT20144430//IG LAMBDA CHAIN V-I REGION BL2
PRECURSOR.//3.80E-55//130aa//83%//P06316
SMINT20144800//Human zinc finger protein zfp6 (ZF6) mRNA, partial
cds.//1.60E-139//354aa//70%//U71363
SMINT20144890
SMINT20152940//Mus musculus ATP-dependent zinc metalloprotease
(Afg311) mRNA, complete cds; nuclear gene for mitochondrial
product.//1.10E-52//75aa//84%//AF329695
SMINT20153260//EXTRACELLULAR MATRIX PROTEIN 1 PRECURSOR (SECRETORY
COMPONENT P85).//3.50E-274//476aa//98%//Q16610
SMINT20153530
SMINT20154540//CHLORINE CHANNEL PROTEIN
P64.//1.10E-135//419aa//68%//P35526
SMINT20155180//Homo sapiens GBAS (GBAS) mRNA, complete
cds.//6.70E-115//142aa//97%//AF029786
SMINT20157450
SMINT20158100
SMINT20161220
SMINT20162860
SMINT20163960
SMINT20164400
SMINT20164770
SMINT20168570//Homo sapiens mRNA for stabilin-1 (stab1
gene).//5.50E-61//128aa//98%//AJ275213
SMINT20173190
SMINT20173240
SMINT20174360//RHYTHMICALLY EXPRESSED GENE 2 PROTEIN
(DREG-2).//6.90E-24//242aa//28%//Q94915
SMINT20177360//SPLICING FACTOR, ARGININE/SERINE-RICH 2 (SPLICING
FACTOR SC35) (SC-35) (SPLICING COMPONENT, 35 KDA) (PR264
PROTEIN).//6.40E-37//82aa//92%//P30352
SMINT20178550
SMINT20179740//IG MU CHAIN C
REGION.//8.50E-248//454aa//99%//P01871
SMINT20183530//GCN20 PROTEIN.//5.50E-118//410aa//52%//P43535
SMINT20190170//IG ALPHA-1 CHAIN C
REGION.//8.50E-199//353aa//100%//P01876
SMINT20191420//AMP DEAMINASE 1 (EC 3.5.4.6) (MYOADENYLATE
DEAMINASE) (AMP DEAMINASE ISOFORM
M).//5.40E-214//401aa//97%//P23109
SMINT20191530//PUTATIVE ATP-DEPENDENT RNA HELICASE
DBP73D.//5.00E-85//547aa//42%//P26802
SMINT20192000
SPLEN10000830
SPLEN20000640
SPLEN20002220
SPLEN20003070
SPLEN20006070//ANKYRIN 1 (ERYTHROCYTE ANKYRIN) (ANKYRIN R)
(ANKYRINS 2.1 AND 2.2).//1.50E-81//788aa//30%//P16157
SPLEN20008390//Human placenta (Diff48) mRNA, complete
cds.//4.60E-108//337aa//60%//U49187
SPLEN20008740//IMPORTIN ALPHA SUBUNIT (KARYOPHERIN ALPHA SUBUNIT)
(SERINE-RICH RNA POLYMERASE I SUPPRESSOR
PROTEIN).//5.50E-12//490aa//22%//Q02821
SPLEN20008820
SPLEN20011410//RHO-GTPASE-ACTIVATING PROTEIN 1 (GTPASE-ACTIVATING
PROTEIN RHOGAP) (RHO-RELATED SMALL GTPASE PROTEIN ACTIVATOR) (CDC42
GTPASE-ACTIVATING PROTEIN)
(P50-RHOGAP).//1.50E-21//183aa//34%//Q07960
SPLEN20013540
SPLEN20016260
SPLEN20019450
SPLEN20020070
SPLEN20021660//GAMMA-GLUTAMYLTRANSPEPTIDASE PRECURSOR (EC 2.3.2.2)
(GAMMA-GLUTAMYLTRANSFERASE)
(GGT).//9.00E-23//167aa//33%//P07314
SPLEN20022230
SPLEN20023140
SPLEN20026950//POSSIBLE GLOBAL TRANSCRIPTION ACTIVATOR SNF2L2
(SNF2-ALPHA).//0//766aa//81%//P51531
SPLEN20027440//ANKYRIN 2 (BRAIN ANKYRIN) (ANKYRIN B) (ANKYRIN,
NONERYTHROID).//6.10E-25//368aa//30%//Q01484
SPLEN20029310
SPLEN20031600
SPLEN20032040
SPLEN20032190
SPLEN20033960
SPLEN20039240//HEAT SHOCK 70 KDA PROTEIN 1 (HSP70.1)
(HSP70-1/HSP70-2).//9.80E-112//213aa//100%//P08107
SPLEN20040600
SPLEN20054290//Fugu rubripes zinc finger protein, isotocin, fatty
acid binding protein, sepiapterin reductase and vasotocin genes,
complete cds.//4.20E-180//448aa//71%//U90880
SPLEN20076530
SPLEN20077500//Mus musculus Niban mRNA, complete
cds.//1.30E-39//351aa//31%//AB049355
SPLEN20079260//ZINC FINGER PROTEIN
132.//6.30E-117//320aa//61%//P52740
SPLEN20079510
SPLEN20084600//RING CANAL PROTEIN (KELCH
PROTEIN).//5.20E-58//558aa//29%//Q04652
SPLEN20095410//ZINC FINGER PROTEIN 184
(FRAGMENT).//6.50E-83//236aa//58%//Q99676
SPLEN20095550
SPLEN20095810
SPLEN20097330
SPLEN20099700//TAT-BINDING HOMOLOG
7.//1.50E-142//553aa//48%//P54816
SPLEN20101190
SPLEN20103950//40S RIBOSOMAL PROTEIN
S17.//7.10E-22//49aa//100%//P.sub.06584
SPLEN20106250
SPLEN20117660//Homo sapiens BCL-6 corepressor (BCOR) mRNA, complete
cds; alternatively spliced.//1.30E-38//139aa//61%//AF317391
SPLEN20118300//Rattus norvegicus amino acid transport system A3
(Ata3) mRNA, complete cds.//1.70E-20//210aa//28%//AF295535
SPLEN20119810
SPLEN20121750//Danio rerio uridine kinase mRNA, complete
cds.//1.60E-29//130aa//50%//AF195851
SPLEN20126190
SPLEN20128000//Xenopus laevis XMAB21 (Xmab-21) mRNA, complete
cds.//6.80E-12//287aa//24%//AF040992
SPLEN20129610
SPLEN20140800//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//1.20E-145//586aa//47%//P51523
SPLEN20141360
SPLEN20141990
SPLEN20142100//Rattus norvegicus alpha D integrin mRNA, complete
cds.//7.10E-37//105aa//76%//AF021334
SPLEN20143180//Mus musculus EWS/FLI1 activated transcript 2 (EAT-2)
mRNA, complete cds.//2.50E-45//132aa//65%//AF020263
SPLEN20144520
SPLEN20145720//Rattus norvegicus nuclear GTPase PIKE mRNA, complete
cds.//2.00E-24//120aa//45%//AF280816
SPLEN20146450//H. sapiens mRNA for plakophilin 2a and
b.//1.20E-08//87aa//42%//X97675
SPLEN20146690
SPLEN20147110//cyclin-E binding protein
1//0//580aa//58%//NP.sub.--057407
SPLEN20147390//ZINC FINGER PROTEIN
136.//1.40E-105//417aa//49%//P52737
SPLEN20149110
SPLEN20149190
SPLEN20149240//Cricetulus longicaudatus arginine
N-methyltransferase p82 isoform mRNA, complete cds, alternatively
spliced.//3.50E-259//525aa//86%//AF336043
SPLEN20150940//Mus musculus histone deacetylase mHDA1 mRNA,
complete cds.//4.20E-187//550aa//51%//AF006602
SPLEN20151210//protein tyrosine phosphatase, non-receptor type
13(AP0-1/CD95 (Fas)-associated
phosphatase)//3.00E-25//250aa//29%//NP.sub.--006255
SPLEN20152610
SPLEN20152760
SPLEN20157300
SPLEN20157880//Homo sapiens Ig superfamily receptor LNIR precursor,
mRNA, complete cds.//1.70E-05//137aa//29%//AF160477
SPLEN20158900
SPLEN20158990
SPLEN20160450//Homo sapiens mRNA for Hrs, complete
cds.//5.60E-28//59aa//100%//D84064
SPLEN20160690
SPLEN20160980
SPLEN20162680//NUCLEAR PROTEIN
SNF7.//4.20E-11//189aa//25%//P39929
SPLEN20163560
SPLEN20165310//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//4.90E-230//477aa//88%//Y14737
SPLEN20166270
SPLEN20167200//Mus musculus MPS1 gene and mRNA,
3'end.//1.50E-15//46aa//84%//L20315
SPLEN20169220
SPLEN20169720
SPLEN20170310//Homo sapiens Asef mRNA for APC-stimulated guanine
nucleotide exchange factor, complete
cds.//8.40E-95//305aa//62%//AB042199
SPLEN20171210
SPLEN20171470
SPLEN20171890
SPLEN20172120
SPLEN20173510//Xenopus laevis putative N-terminal acetyltransferase
mRNA, complete cds.//3.90E-210//413aa//66%//AF247679
SPLEN20174260
SPLEN20176200
SPLEN20179180//Homo sapiens EH domain containing 2 (EHD2) mRNA,
complete cds.//1.10E-181//340aa//94%//AF181263
SPLEN20179810//Mus musculus pecanex 1 mRNA, complete
cds.//3.80E-131//534aa//51%//AF096286
SPLEN20181810//Mus musculus faciogenital dysplasia protein 2 (Fgd2)
mRNA, complete cds.//6.60E-68//144aa//86%//AF017368
SPLEN20186430//PROBABLE G PROTEIN-COUPLED RECEPTOR
APJ.//2.20E-163//226aa//96%//P35414
SPLEN20193110
SPLEN20194050//Homo sapiens HOTTL protein mRNA, complete
cds.//9.50E-135//264aa//93%//AF078842
SPLEN20198110
SPLEN20204170
SPLEN20211220
SPLEN20211570
SPLEN20211940
SPLEN20212730//CALPAIN 2, LARGE [CATALYTIC] SUBUNIT (EC 3.4.22.17)
(CALCIUM-ACTIVATED NEUTRAL PROTEINASE) (CANP)
(M-TYPE).//1.70E-137//265aa//98%//P17655
SPLEN20212950
SPLEN20213830
SPLEN20214400
SPLEN20214580//Mus musculus mdg1-1 mRNA, complete
cds.//1.40E-16//39aa//94%//AF190624
SPLEN20222270//Mus musculus adaptor protein (Dokl) mRNA, complete
cds.//1.10E-42//123aa//61%//AF179242
SPLEN20225220
SPLEN20242320
SPLEN20242730
SPLEN20243830//TRANSCRIPTION INITIATION FACTOR TFIID 135 KDA
SUBUNIT (TAFII-135) (TAFII135) (TAFII-130)
(TAFII130).//4.70E-38//98aa//87%//000268
SPLEN20245300//ADP-ribosylation factor binding protein
GGA1//3.00E-39//120aa//76%//NP.sub.--037497
SPLEN20249560
SPLEN20250170//PUTATIVE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE
FACTOR(RHO/RAC GEF) (FACIOGENITAL DYSPLASIA PROTEIN
HOMOLOG).//1.40E-51//488aa//27%//P52734
SPLEN20250390//CALPAIN 1, LARGE [CATALYTIC] SUBUNIT (EC 3.4.22.17)
(CALCIUM-ACTIVATED NEUTRAL PROTEINASE) (CANP)
(MU-TYPE).//3.00E-55//115aa//94%//P07384
SPLEN20252190//ZINC FINGER PROTEIN
135.//6.00E-89//303aa//52%//P52742
SPLEN20261440
SPLEN20264110
SPLEN20267650//ZINC FINGER PROTEIN 184
(FRAGMENT).//5.20E-90//410aa//45%//Q99676
SPLEN20273950
SPLEN20279950
SPLEN20280660
SPLEN20283650//Mus musculus ras activator RasGRP (Rasgrp) mRNA,
complete cds.//9.80E-54//182aa//57%//AF106070
SPLEN20284240//Homo sapiens hOBDPF mRNA for osteoblast
differentiation promoting factor, complete
cds.//9.80E-93//177aa//98%//AB048363
SPLEN20292950//ATP-binding cassette, sub-family A member
8//3.30E-211//469aa//64%//NP.sub.--009099
SPLEN20293800
SPLEN20303970
SPLEN20304950//Homo sapiens CAGH32 mRNA, partial
cds.//9.60E-44//86aa//98%//U80743
SPLEN20305620//DIHYDROOROTATE DEHYDROGENASE PRECURSOR (EC 1.3.3.1)
(DIHYDROOROTATE OXIDASE)
(FRAGMENT).//3.60E-59//124aa//96%//Q02127
SPLEN20329240
STOMA20001830//IG ALPHA-1 CHAIN C
REGION.//2.10E-196//353aa//99%//P01876
STOMA20005390//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
STOMA20005670//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//1.90E-216//478aa//83%//Y14737
STOMA20006400//Homo sapiens IGHG3 gene for immunoglobulin heavy
chain gamma 3 constant region, 4-exon hinge, isolate
Lib-A2.//8.40E-214//377aa//100%//AJ390247
STOMA20006780
STOMA20006860//Homo sapiens TOB3 mRNA, complete
cds.//1.80E-74//159aa//97%//AF343078
STOMA20008880//MYOCILIN PRECURSOR (TRABECULAR MESHWORK-INDUCED
GLUCOCORTICOID RESPONSE
PROTEIN).//1.00E-196//405aa//91%//Q99972
STOMA20010250//Homo sapiens RNA-binding protein (RBMS3) mRNA,
complete cds.//7.70E-46//116aa//86%//AF023259
STOMA20013890
STOMA20026880
STOMA20032890//ZINC FINGER PROTEIN
CKR1.//5.80E-30//162aa//38%//P30373
STOMA20034770//IG ALPHA-1 CHAIN C
REGION.//4.40E-196//353aa//99%//P01876
STOMA20036460
STOMA20046680//FOSB PROTEIN (G0/G1 SWITCH REGULATORY PROTEIN
3).//4.10E-14//36aa//100%//P53539
STOMA20048520
STOMA20048840
STOMA20051200
STOMA20056640//Ig lambda chain V
region//6.80E-54//150aa//73%//S23626
STOMA20056670//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
STOMA20057820
STOMA20062130//IG KAPPA CHAIN V-III REGION HAH
PRECURSOR.//3.10E-53//129aa//80%//P18135
STOMA20062290
STOMA20063250//TRANSCRIPTION FACTOR COE3 (EARLY B-CELL FACTOR 3)
(EBF-3) (OLF-1/EBF-LIKE 2) (OE-2)
(O/E-2).//7.50E-50//105aa//93%//008791
STOMA20063980
STOMA20064470//PLACENTAL RIBONUCLEASE INHIBITOR
(RIBONUCLEASE/ANGIOGENIN INHIBITOR) (RAI)
(R1).//3.60E-14//262aa//30%//P13489
STOMA20067800
STOMA20069040
STOMA20072690
STOMA20076800
STOMA20077450//UBIQUITIN-ACTIVATING ENZYME E1 (A1S9
PROTEIN).//2.70E-228//430aa//97%//P22314
STOMA20080500//ATP-binding cassette, sub-family A, member 7,
isoform a//1.00E-297//538aa//94%//NP.sub.--061985
STOMA20083610//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
STOMA20086140
STOMA20088380//IG ALPHA-1 CHAIN C
REGION.//2.10E-196//352aa//100%//P01876
STOMA20092530//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//3.10E-239//477aa//91%//Y14737
STOMA20092560
STOMA20092890
SYNOV20001520//Homo sapiens kappa 1 immunoglobulin light chain
mRNA, complete cds.//5.50E-107//236aa//86%//AF113887
SYNOV20001730//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//2.60E-226//479aa//86%//M87789
SYNOV20002510//Homo sapiens IGHG3 gene for immunoglobulin heavy
chain gamma 3 constant region, 4-exon hinge, isolate
Kp-25.//6.60E-214//377aa//100%//AJ390254
SYNOV20002790//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//1.30E-238//476aa//91%//M87789
SYNOV20002970//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//7.00E-226//476aa//86%//M87789
SYNOV20003970
SYNOV20004260//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//1.10E-225//477aa//86%//Y14737
SYNOV20007000//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//4.00E-239//478aa//91%//M87789
SYNOV20008240//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//4.10E-237//479aa//90%//M87789
SYNOV20009230//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
SYNOV20010880//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//1.60E-233//476aa//89%//M87789
SYNOV20011110//Human (hybridoma H210) anti-hepatitis A IgG variable
region, constant region, complementarity-determining regions mRNA,
complete cds.//6.90E-235//476aa//89%//M87789
SYNOV20013000//Ig gamma=immunoglobulin heavy chain [rats, humanized
lympholytic MoAb CAMPATH-1H, mRNA, 1465
nt].//7.70E-220//472aa//86%//S79307
SYNOV20013560//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//1.40E-234//477aa//89%//Y14737
SYNOV20013900//Homo sapiens mRNA for immunoglobulin kappa heavy
chain.//3.50E-231//476aa//89%//Y14735
SYNOV20017080
SYNOV30001840
TBAES20000590
TBAES20002550//AMINOPEPTIDASE B (EC 3.4.11.6) (ARGINYL
AMINOPEPTIDASE) (ARGININE AMINOPEPTIDASE) (CYTOSOL AMINOPEPTIDASE
IV) (AP-B).//2.10E-310//586aa//89%//009175
TBAES20003150//CYTOCHROME P450 4A1 (EC 1.14.15.3) (CYPIVA1) (LAURIC
ACID OMEGA-HYDROXYLASE) (P450-LA-OMEGA 1)
(P452).//1.40E-82//323aa//44%//P08516
TBAES20003770//SPERM-SPECIFIC ANTIGEN 2 (CLEAVAGE SIGNAL-1 PROTEIN)
(CS-1).//1.90E-122//249aa//97%//P28290
TCOLN20001390
TESOP20000900
TESOP20003120
TESOP20004000//CATHEPSIN B PRECURSOR (EC 3.4.22.1) (CATHEPSIN B1)
(APP SECRETASE).//3.30E-111//194aa//98%//P07858
[0624] TESOP20005270//MONOAMINE-SULFATING PHENOL SULFOTRANSFERASE
(EC 2.8.2.1) (SULFOTRANSFERASE, MONOAMINE-PREFERRING) (M-PST)
(THERMOLABILE PHENOL SULFOTRANSFERASE) (TL-PST) (PLACENTAL ESTROGEN
SULFOTRANSFERASE) (CATECHOLAMINE-SULFATING PHENOL SULFOTRANSFERASE)
(HAST3).//3.40E-47//92aa//100%//P50224
TESOP20005690//Mus musculus p53 apoptosis-associated target (Perp)
mRNA, complete cds.//2.30E-53//113aa//91%//AF249870
TESTI10000940
TESTI20001000//FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (EC 3.2.2.23)
(FAPY-DNA GLYCOSYLASE).//7.80E-06//238aa//28%//P74290
TESTI20001170
TESTI20001720
TESTI20002720//TUBULIN-TYROSINE LIGASE (EC 6.3.2.25)
(TTL).//1.70E-18//237aa//29%//P38584
TESTI20002780//ADENYLATE CYCLASE (EC 4.6.1.1) (ATP
PYROPHOSPHATE-LYASE) (ADENYLYL
CYCLASE).//1.90E-11//140aa//36%//P08678
TESTI20004890
TESTI20011200
TESTI20017950
TESTI20018230
TESTI20023510
TESTI20029930
TESTI20030310
TESTI20030890
TESTI20031270//TUMOR NECROSIS FACTOR, ALPHA-INDUCED PROTEIN 1,
ENDOTHELIAL (B12 PROTEIN).//7.30E-52//146aa//71%//Q13829
TESTI20031810
TESTI20035960//VEGETATIBLE INCOMPATIBILITY PROTEIN
HET-E-1.//1.70E-67//329aa//40%//Q00808
TESTI20036380//DRA PROTEIN (DOWN-REGULATED IN
ADENOMA).//6.40E-46//243aa//35%//P40879
TESTI20037560
TESTI20038270
TESTI20039400//EBNA-1 NUCLEAR
PROTEIN.//3.60E-43//298aa//43%//P03211
TESTI20041690//TRANSCRIPTION INTERMEDIARY FACTOR 1-BETA (KRAB-A
INTERACTING PROTEIN) (KRIP-1).//1.00E-12//341aa//21%//Q62318
TESTI20044230//Mus musculus testis-specific Y-encoded-like protein
(Tspyl1) mRNA, complete cds.//1.70E-94//291aa//64%//AF042180
TESTI20044310//RAS SUPPRESSOR PROTEIN 1 (RSU-1) (RSP-1 PROTEIN)
(RSP-1).//6.70E-06//118aa//32%//Q15404
TESTI20046750
TESTI20057750
TESTI20060400//Columba livia mRNA for
5'-nucleotidase.//3.80E-115//328aa//66%//AJ131243
TESTI20061110//Xenopus laevis katanin p60 mRNA, partial
cds.//1.80E-170//489aa//66%//AF177942
TESTI20063830//Drosophila melanogaster nuclear fallout (nuf) mRNA,
nuf-1 allele, complete cds.//2.10E-34//371aa//29%//AF045015
TESTI20066670//probable acyl-CoA
dehydrogenase//1.90E-72//222aa//60%//D75616
TESTI20066770
TESTI20067200//PRE-B-CELL LEUKEMIA TRANSCRIPTION FACTOR-3 (HOMEOBOX
PROTEIN PBX3).//4.20E-132//352aa//71%//P40426
TESTI20076850
TESTI20082330//helicase II
homolog//4.10E-44//775aa//25%//T13889
TESTI20083200//Homo sapiens mitogen-activated protein kinase
phosphatase x (MKPX) mRNA, complete
cds.//1.00E-41//131aa//58%//AF165519
TESTI20083940
TESTI20086210
TESTI20087620
TESTI20088220//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//8.50E-175//633aa//48%//Q05481
TESTI20094020
TESTI20094120
TESTI20094230//Strongylocentrotus purpuratus tektin A1 mRNA,
complete cds//4.50E-64//252aa//50%//M97188
TESTI20094470//ETS-RELATED PROTEIN 71 (ETS TRANSLOCATION VARIANT
2).//1.40E-183//318aa//99%//000321
TESTI20098350
TESTI20098530
TESTI20102800
TESTI20105720
TESTI20108720//PROTEIN PHOSPHATASE 2C BETA ISOFORM (EC 3.1.3.16)
(PP2C-BETA) (IA) (PROTEIN PHOSPHATASE
1B).//3.30E-49//249aa//46%//P36993
TESTI20110280
TESTI20112940
TESTI20114070
TESTI20116650
TESTI20116830//Homo sapiens liprin-beta2 mRNA, partial
cds.//8.20E-17//50aa//92%//AF034803
TESTI20121550//NUCLEOPORIN-LIKE PROTEIN RIP (REV INTERACTING
PROTEIN) (REV/REX ACTIVATION DOMAIN-BINDING
PROTEIN).//1.60E-152//363aa//85%//P52594
TESTI20122310
TESTI20123080
TESTI20123560
TESTI20127760
TESTI20128350
TESTI20129150
TESTI20129220
TESTI20130010//ZINC FINGER PROTEIN 84 (ZINC FINGER PROTEIN
HPF2).//2.10E-63//173aa//65%//P51523
TESTI20130120
TESTI20135660
TESTI20136100//ZINC/CADMIUM RESISTANCE
PROTEIN.//3.70E-12//101aa//35%//P20107
TESTI20136710
TESTI20136990
TESTI20137370
TESTI20137670
TESTI20143240
TESTI20143390//Mus musculus testicular condensing enzyme (AMAC1)
mRNA, complete cds.//1.60E-51//123aa//79%//AF016712
TESTI20143620
TESTI20148000//PROTEIN DISULFIDE ISOMERASE (PDI) (EC 5.3.4.1)
(PROLYL 4-HYDROXYLASE BETA SUBUNIT) (CELLULAR THYROID HORMONE
BINDING PROTEIN) (RETINA COGNIN)
(R-COGNIN).//2.80E-75//493aa//34%//P09102
TESTI20152460//ML02 PROTEIN.//9.60E-42//170aa//40%//Q09329
TESTI20155900
TESTI20156100//KRUPPEL-LIKE FACTOR 4 (EPITHELIAL ZINC-FINGER
PROTEIN EZF).//2.30E-32//254aa//32%//043474
TESTI20157100
TESTI20157520
TESTI20159140
TESTI20161970
TESTI20164100
TESTI20168480//H. sapiens mRNA for titin protein (clone
hh1-hh54).//6.30E-48//393aa//31%//X90568
TESTI20168630
TESTI20168960
TESTI20169960
TESTI20170350
TESTI20171020
TESTI20178160
TESTI20179320
TESTI20183370
TESTI20184620//OXYSTEROL-BINDING
PROTEIN.//6.20E-27//181aa//28%//P16258
TESTI20185650//Xenopus laevis ubiquitin-like fusion protein mRNA,
complete cds.//2.90E-129//543aa//46%//L08474
TESTI20185810
TESTI20189410//Mus musculus axotrophin mRNA, complete
cds.//7.50E-43//142aa//57%//AF155739
TESTI20192280
TESTI20192800//Homo sapiens nasopharyngeal carcinoma susceptibility
protein LZ16 mRNA, complete
cds.//2.40E-23//164aa//41%//AF121775
TESTI20193360
TESTI20194300
TESTI20194810
TESTI20197940
TESTI20199170
TESTI20199750//TRICHOHYALIN.//8.80E-59//547aa//30%//P37709
TESTI20200260
TESTI20200710//Mus musculus epithelial protein lost in neoplasm-a
(Eplin) mRNA, complete cds.//4.40E-40//212aa//42%//AF307844
TESTI20202650
TESTI20203440
TESTI20204450//M. musculus of DNA encoding DNA-binding
protein.//1.90E-58//477aa//32%//Z54200
TESTI20208400//PROLIFERATING-CELL NUCLEOLAR ANTIGEN P120
(PROLIFERATION-ASSOCIATED NUCLEOLAR PROTEIN
P120).//1.70E-16//181aa//33%//P46087
TESTI20208710
TESTI20209460
TESTI20209810
TESTI20209990
TESTI20211160
TESTI20211220
TESTI20211240
TESTI20213150
TESTI20213580
TESTI20214250//MITOCHONDRIAL CARRIER PROTEIN
PMT.//1.10E-34//242aa//36%//P32332
TESTI20215990//Homo sapiens leucine-rich repeats containing F-box
protein FBL3 mRNA, complete
cds.//1.10E-39//375aa//28%//AF186273
TESTI20216370//LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1)
(ES-MALE) (ESTERASE-31).//1.50E-60//164aa//68%//Q63880
TESTI20220100
TESTI20220650
TESTI20224620
TESTI20226230//Rattus norvegicus KPL2 (Kpl2) mRNA, complete
cds.//8.90E-111//371aa//59%//AF102129
TESTI20226490
TESTI20229600//Drosophila melanogaster SP2353 mRNA, complete
cds.//8.30E-117//607aa//33%//AF239610
TESTI20230250
TESTI20230850//CIRCADIAN LOCOMOTER OUTPUT CYCLES KAPUT PROTEIN
(MCLOCK).//1.00E-23//186aa//30%//008785
TESTI20231920
TESTI20231940//Human OB binding protein-2 (OB-BP2) mRNA, complete
cds.//4.60E-14//140aa//36%//U71383
TESTI20232140//1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1)
(PHOSPHOLIPASE C-DELTA-1) (PLC-III)
(FRAGMENT).//2.50E-90//388aa//47%//P10895
TESTI20234140
TESTI20234270
TESTI20234360//PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING
1 (EC 5.2.1.8).//5.90E-66//128aa//98%//Q13526
TESTI20237520//poly(A)-specific ribonuclease (deadenylation
nuclease)//1.10E-34//311aa//26%//NP.sub.--002573
TESTI20238000
TESTI20238610//MELANOMA-ASSOCIATED ANTIGEN B1 (MAGE-B1 ANTIGEN)
(MAGE-XP ANTIGEN) (DAM10).//6.80E-69//268aa//51%//P43366
TESTI20239470
TESTI20239510//ubiquitin specific protease
6//5.60E-43//182aa//50%//NP.sub.--004496
TESTI20240090
TESTI20241530
TESTI20241920
TESTI20242830
TESTI20242990
TESTI20244190//Homo sapiens IGHG3 gene for immunoglobulin heavy
chain gamma 3 constant region, 4-exon hinge, isolate
Lib-A2.//8.40E-214//377aa//100%//AJ390247
TESTI20244760
TESTI20249990//ATAXIN 7 (SPINOCEREBELLAR ATAXIA TYPE 7
PROTEIN).//7.30E-49//388aa//37%//015265
TESTI20254220
TESTI20254540//Homo sapiens hepatocellular carcinoma-associated
antigen 59 mRNA, complete cds.//1.60E-100//197aa//98%//AF218421
TESTI20254860//TUMOR SUPPRESSOR PROTEIN DCC
PRECURSOR.//1.20E-35//564aa//28%//P70211
TESTI20255820
TESTI20258460//Homo sapiens OSBP-related protein 4 mRNA, complete
cds.//8.20E-196//369aa//99%//AF323731
TESTI20262330
TESTI20262910
TESTI20265250
TESTI20265370
TESTI20265970
TESTI20266740//Homo sapiens topoisomerase-related function protein
(TRF4-1) mRNA, partial cds.//2.70E-105//278aa//71%//AF089896
TESTI20269570
TESTI20271850
TESTI20272060
TESTI20272390
TESTI20272960//Mus musculus gene for odorant receptor MOR83,
complete cds.//3.30E-84//306aa//50%//AB030894
TESTI20275030
TESTI20275620
TESTI20277360
TESTI20278200
TESTI20278400//INTRACELLULAR PROTEIN TRANSPORT PROTEIN
USO1.//2.50E-11//604aa//21%//P25386
TESTI20280980
TESTI20282540
TESTI20284880
TESTI20285830
TESTI20288110
TESTI20288910//Mus musculus endophilin II mRNA, complete
cds.//2.10E-110//225aa//92%//U58885
TESTI20289850
TESTI20291310
TESTI20291620
TESTI20291960//RHOMBOID PROTEIN (VEINLET
PROTEIN).//2.00E-40//230aa//38%//P20350
TESTI20294700
TESTI20297850
TESTI20301360
TESTI20303220//Rattus norvegicus neural cell adhesion protein BIG-2
precursor (BIG-2) mRNA, complete cds.//0//807aa//94%//U35371
TESTI20303360
TESTI20303420
TESTI20305540//M. musculus mRNA for
IB3/5-polypeptide.//1.30E-183//684aa//56%//X79131
TESTI20305560
TESTI20307540
TESTI20307700
TESTI20308600
TESTI20309170//Mucor circinelloides crgA gene for carotenoid
regulatory protein.//3.10E-41//198aa//40%//AJ250998
TESTI20310070
TESTI20311290
TESTI20314180//TRYPSIN I-PI PRECURSOR (EC
3.4.21.4).//2.10E-25//86aa//40%//Q90627
TESTI20316870//Homo sapiens mRNA for cartilage-associated protein
(CASP).//4.90E-106//199aa//99%//AJ006470
TESTI20317600
TESTI20318090//ZINC FINGER PROTEIN
135.//2.00E-56//208aa//50%//P52742
TESTI20319190
TESTI20320440//THIOREDOXIN.//4.30E-32//103aa//63%//P50413
TESTI20320670//Rattus norvegicus mRNA for type A/B hnRNP protein
p40.//2.20E-170//337aa//91%//AJ238854
TESTI20326810//RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN (RAN BINDING
PROTEIN 1) (RANBP1).//2.00E-33//66aa//100%//P34022
TESTI20327680
TESTI20327740
TESTI20328280
TESTI20330310
TESTI20332420//Mus musculus cell cycle checkpoint control protein
Mrad9 gene, complete cds.//5.80E-20//246aa//28%//AF045662
TESTI20333000
TESTI20333950
TESTI20334410//Sus scrofa RNA helicase (RHIV-1) mRNA, complete
cds.//4.40E-58//281aa//33%//AF181119
TESTI20335050//Homo sapiens cell cycle checkpoint protein CHFR
mRNA, complete cds.//6.00E-188//333aa//99%//AF170724
TESTI20335200//BILIARY GLYCOPROTEIN 1 PRECURSOR (BGP-1) (ANTIGEN
CD66) (CD66A ANTIGEN).//8.10E-20//87aa//50%//P13688
TESTI20336410
TESTI20337100
TESTI20342430
TESTI20343070
TESTI20343570//TRIPEPTIDYL-PEPTIDASE II (EC 3.4.14.10) (TPP II)
(TRIPEPTIDYL AMINOPEPTIDASE).//2.00E-75//201aa//75%//P29144
TESTI20345060
TESTI20347180//Mus musculus membrane protein TMS-2 mRNA, complete
cds.//6.00E-35//186aa//41%//AF181685
TESTI20347300
TESTI20347740
TESTI20347770
TESTI20351830
[0625] TESTI20352620//PROACTIVATOR POLYPEPTIDE PRECURSOR [CONTAINS:
SAPOSIN A (PROTEIN A); SAPOSIN B (SPHINGOLIPID ACTIVATOR PROTEIN 1)
(SAP-1) (DISPERSIN) (SULFATIDE/GM1 ACTIVATOR); SAPOSIN
C(CO-BETA-GLUCOSIDASE) (A1 ACTIVATOR) (GLUCOSYLCERAMIDASE
ACTIVATOR) (SPHINGOLIPID ACTIVATOR PROTEIN 2) (SAP-2); SAPOSIN D
(PROTEIN C) (COMPONENT C)].//1.30E-52//240aa//44%//P07602
TESTI20355020//Drosophila sp. Hls (hls) mRNA, complete
cds.//9.80E-30//416aa//28%//S79915
TESTI20357750
TESTI20357930
TESTI20357960
TESTI20358980//Volvox carteri mRNA for hydroxyproline-rich
glycoprotein (HRGP gene).//2.90E-37//155aa//50%//AJ242540
TESTI20361140
TESTI20366910//Homo sapiens mRNA for thioredoxin reductase II beta,
complete cds.//2.00E-233//442aa//93%//AB019695
TESTI20367360
TESTI20368330//M-PHASE INDUCER PHOSPHATASE 3 (EC
3.1.3.48).//2.10E-258//473aa//99%//P30307
TESTI20369130
TESTI20369220
TESTI20369650//Homo sapiens mRNA for HsGAK, complete
cds.//2.40E-269//493aa//99%//D88435
TESTI20369690
TESTI20370020
TESTI20370550
TESTI20370810//Homo sapiens mRNA for LAK-4p, complete
cds.//1.10E-74//385aa//38%//AB002405
TESTI20371030//TIP ELONGATION ABERRANT PROTEIN 1 (CELL POLARITY
PROTEIN TEA1).//7.80E-23//243aa//29%//P87061
TESTI20371060
TESTI20373820
TESTI20375340//1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1)
(PHOSPHOLIPASE C-DELTA-1) (PLC-III)
(FRAGMENT).//4.80E-68//273aa//45%//P10895
TESTI20377230
TESTI20378190//ZINC FINGER PROTEIN 91 (ZINC FINGER PROTEIN HTF10)
(HPF7).//2.30E-114//323aa//52%//Q05481
TESTI20378450
TESTI20380650
TESTI20381040
TESTI20382750//Homo sapiens hook1 protein (HOOK1) mRNA, complete
cds.//2.60E-96//195aa//99%//AF044923
TESTI20383880//Homo sapiens gamma cysteine string protein mRNA,
partial cds.//6.50E-61//109aa//100%//AF368277
TESTI20385960//Homo sapiens mRNA for RET finger protein-like
3.//4.80E-156//288aa//100%//AJ010232
TESTI20386230
TESTI20386440
TESTI20388580
TESTI20390260
TESTI20390410
TESTI20391130
TESTI20391210
TESTI20391770
TESTI20392090
TESTI20392250//Homo sapiens VAV-3 protein mRNA, complete
cds.//9.80E-145//268aa//98%//AF067817
TESTI20392270
TESTI20392760//PROTEIN PHOSPHATASES PP1 REGULATORY SUBUNIT
SDS22.//5.70E-22//226aa//31%//P36047
TESTI20393530//MITOCHONDRIAL PHOSPHATE CARRIER PROTEIN PRECURSOR
(PTP).//9.00E-34//105aa//68%//P12234
TESTI20396130
TESTI20397760//POTENTIAL PHOSPHOLIPID-TRANSPORTING ATPASE IIB (EC
3.6.1.-).//1.60E-109//221aa//90%//P98195
TESTI20400940//CENTROMERIC PROTEIN E (CENP-E
PROTEIN).//4.70E-16//669aa//23%//Q02224
TESTI20401020//Oryctolagus cuniculus peroxisomal Ca-dependent
solute carrier mRNA, complete
cds.//5.80E-64//234aa//56%//AF004161
TESTI20401280
TESTI20401430
TESTI20404240//INTERFERON-RELATED DEVELOPMENTAL REGULATOR 2 (SKMC15
PROTEIN).//4.60E-36//46aa//93%//Q12894
TESTI20406420
TESTI20408150
TESTI20408970//NUCLEAR ENVELOPE PORE MEMBRANE PROTEIN POM 121 (PORE
MEMBRANE PROTEIN OF 121 KDA)
(P145).//4.30E-16//264aa//30%//P52591
TESTI20409440
TESTI20409890//GCD14 PROTEIN.//2.30E-46//263aa//40%//P46959
TESTI20413300
TESTI20415170
TESTI20415640
TESTI20416640//CHOLINE/ETHANOLAMINE KINASE [INCLUDES: CHOLINE
KINASE (EC 2.7.1.32) (CK); ETHANOLAMINE KINASE (EC 2.7.1.82)
(EK)].//2.10E-77//139aa//100%//Q9Y259
TESTI20417300//DYNEIN BETA CHAIN,
CILIARY.//6.80E-129//552aa//45%//P39057
TESTI20419560
TESTI20420620//TRANSCRIPTION INITIATION FACTOR TFIID 70 KDA SUBUNIT
(TAFII-70) (TAFII-80) (TAFII80).//0//526aa//99%//P49848
TESTI20421490
TESTI20422640
TESTI20423020
TESTI20424000
TESTI20424730
TESTI20425070
TESTI20427830
TESTI20428060
TESTI20429280
TESTI20429580
TESTI20432750//Mus musculus pantothenate kinase 1 beta (panKlbeta)
mRNA, complete cds.//9.70E-165//363aa//82%//AF200357
TESTI20432820//ZINC FINGER PROTEIN 43 (ZINC PROTEIN
HTF6).//1.00E-173//403aa//75%//P28160
TESTI20433130
TESTI20436560//LAMIN C.//9.20E-235//453aa//99%//PO.sub.2546
TESTI20438570//Homo sapiens nolp mRNA, complete
cds.//2.70E-43//146aa//60%//AB017800
TESTI20438660
TESTI20441940//Human K-Cl cotransporter (hKCC1) mRNA, complete
cds.//5.50E-139//264aa//99%//U55054
TESTI20442760//Homo sapiens Ig-like membrane protein (IGSF3) mRNA,
complete cds.//0//545aa//93%//AF031174
TESTI20443090//DNA REPAIR PROTEIN RAD51 HOMOLOG 4 (R51H3)
(TRAD).//2.70E-68//141aa//100%//075771
TESTI20444130
TESTI20444180
TESTI20447540
TESTI20449200//METABOTROPIC GLUTAMATE RECEPTOR 7
PRECURSOR.//9.00E-173//313aa//99%//Q14831
TESTI20451710
TESTI20451990
TESTI20455090//KERATIN, TYPE I CYTOSKELETAL 18 (CYTOKERATIN 18)
(K18) (CK 18).//1.20E-76//199aa//80%//P05783
TESTI20455620//HEAT SHOCK-RELATED 70 KDA PROTEIN 2 (HEAT SHOCK 70
KDA PROTEIN 2).//4.80E-218//336aa//99%//P54652
TESTI20456110//52 KDA RO PROTEIN (SJOGREN SYNDROME TYPE A ANTIGEN
(SS-A)) (RO(SS-A)).//9.40E-75//382aa//43%//P19474
TESTI20458190
TESTI20463520
TESTI20463580//UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 4 (EC
3.1.2.15) (UBIQUITIN THIOLESTERASE 4) (UBIQUITIN-SPECIFIC
PROCESSING PROTEASE 4) (DEUBIQUITINATING ENZYME 4) (UBIQUITOUS
NUCLEAR PROTEIN HOMOLOG).//1.50E-17//190aa//28%//Q13107
TESTI20465350//2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE (EC
3.1.4.37) (CNP) (CNPASE).//2.20E-123//231aa//100%//P09543
TESTI20465520
TESTI20465690//Homo sapiens Borg4 mRNA, complete
cds.//2.00E-152//235aa//99%//AB042237
TESTI20467210//Homo sapiens mRNA for HELG
protein.//2.00E-166//368aa//83%//AJ277291
TESTI20467320//Mus musculus WAVE-1 mRNA, complete
cds.//1.20E-111//233aa//88%//AF290877
TESTI20467970
TESTI20468630
TESTI20471410//PROTEIN PHOSPHATASE 2C ALPHA ISOFORM (EC 3.1.3.16)
(PP2C-ALPHA) (IA) (PROTEIN PHOSPHATASE
IA).//1.30E-210//382aa//99%//P35813
TESTI20471470
TESTI20471530
TESTI20472120
TESTI20473420
TESTI20473830//Columba livia mRNA for
5'-nucleotidase.//2.00E-14//75aa//49%//AJ131243
TESTI20477920
TESTI20478010
TESTI20478180
TESTI20478850
TESTI20479300
THYMU10005360//Human T cell receptor beta chain (TCRB) mRNA, VNDNJC
region, 5'end.//1.20E-130//270aa//91%//L07294
THYMU10005540//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//1.20E-237//479aa//90%//Y14737
THYMU20000570
THYMU20011950
THYMU20015210
THYMU20018190
THYMU20023380//Homo sapiens m6A methyltransferase (MT-A70) gene,
complete cds.//1.20E-38//86aa//100%//AF014837
THYMU20027560
THYMU20029100
THYMU20032870
THYMU20039810//MPS1 protein//2.60E-283//646aa//77%//152603
THYMU20045120
THYMU20058070
THYMU20061700
THYMU20066100
THYMU20070360
THYMU20075320
THYMU20081490//Homo sapiens ICB-1 mRNA, complete
cds.//1.50E-23//267aa//33%//AF044896
THYMU20095960
THYMU20100410
THYMU20101610
THYMU20101920
THYMU20105190//MYOSIN I ALPHA
(MMI-ALPHA).//7.50E-54//282aa//45%//P46735
THYMU20106710//Homo sapiens T-cell receptor alpha delta locus from
bases 501613 to 752736 (section 3 of 5) of the Complete Nucleotide
Sequence.//1.20E-54//113aa//98%//AE000660
THYMU20108310//Mouse NCBP-29 mRNA for PW29, complete
cds.//7.70E-93//102aa//99%//D49429
THYMU20111180
THYMU20111420
THYMU20111830//protease, serine, 16
(thymus)//1.40E-129//175aa//98%//NP.sub.--005856
THYMU20114470
THYMU20115850
THYMU20118060
THYMU20118520//Xenopus laevis ubiquitin-like fusion protein mRNA,
complete cds//3.00E-42//109aa//77%//L08475
THYMU20119390
THYMU20122730//target of mybl (chicken)
homolog//1.00E-122//233aa//100%//NP.sub.--005479
THYMU20126900//UDP-GLUCOSE 6-DEHYDROGENASE (EC 1.1.1.22) (UDP-GLC
DEHYDROGENASE) (UDP-GLCDH)
(UDPGDH).//1.40E-229//341aa//99%//060701
THYMU20128070
THYMU20128260
THYMU20130890//40S RIBOSOMAL PROTEIN
S16.//1.90E-28//125aa//57%//P17008
THYMU20141670
THYMU20142040//WISKOTT-ALDRICH SYNDROME PROTEIN HOMOLOG
(WASP).//2.60E-12//155aa//32%//P70315
THYMU20142970
THYMU20143270//Homo sapiens HSNFRK (HSNFRK) mRNA, complete
cds.//5.40E-171//321aa//100%//AF226044
THYMU20147770//Homo sapiens mRNA for immunoglobulin lambda heavy
chain.//5.40E-235//477aa//89%//Y14737
THYMU20153160
THYMU20158250
THYMU20159430//IG ALPHA-1 CHAIN C
REGION.//7.90E-197//353aa//100%//P01876
THYMU20161640//Mus musculus p53 apoptosis-associated target (Perp)
mRNA, complete cds.//1.40E-92//188aa//89%//AF249870
THYMU20162190
THYMU20169680//DIACYLGLYCEROL KINASE, ZETA (EC 2.7.1.107)
(DIGLYCERIDE KINASE) (DGK-ZETA) (DAG KINASE
ZETA).//1.40E-64//124aa//99%//Q13574
THYMU20172150//CORONIN-LIKE PROTEIN P57 (CORONIN
1A).//1.60E-49//96aa//100%//P31146
THYMU20173980
THYMU20180280//RED PROTEIN (RER PROTEIN) (IK FACTOR) (CYTOKINE
IK).//2.60E-40//83aa//96%//Q13123
THYMU20186390
THYMU20186730
THYMU20187720
THYMU20193640//HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN L (HNRNP
L).//1.70E-82//157aa//99%//P14866
THYMU20194360
THYMU20194420
THYMU20195990
THYMU20201980//Mus musculus faciogenital dysplasia protein 2 (Fgd2)
mRNA, complete cds.//2.90E-122//259aa//86%//AF017368
THYMU20202890//PROTEIN KINASE CLK3 (EC
2.7.1.-).//1.10E-204//367aa//99%//035492
THYMU20204160
THYMU20204990
THYMU20208300
THYMU20209590//DYNAMIN 2.//2.10E-189//363aa//97%//P50570
THYMU20215090
THYMU20215970
THYMU20216840
THYMU20222890
THYMU20226600
THYMU20228540
THYMU20229220
THYMU20232090//SYNTAXIN BINDING PROTEIN 2 (UNC-18 HOMOLOG 2)
(UNC-18B).//2.10E-54//112aa//99%//Q15833
THYMU20235760
THYMU20239000//collagen alpha 1(XI)
chain//1.70E-37//579aa//33%//S18251
THYMU20239430
THYMU20240710//Halocynthia roretzi mRNA for HrPET-3, complete
cds.//5.60E-54//155aa//44%//AB029335
THYMU20241210//Homo sapiens mRNA for nuclear protein, NP220,
complete cds.//2.00E-58//117aa//100%//D83032
THYMU20241850//HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DX BETA
CHAIN PRECURSOR.//4.40E-141//261aa//100%//P05538
THYMU20246840
THYMU20247480//ZINC FINGER PROTEIN
135.//1.20E-97//191aa//90%//P52742
THYMU20250420
THYMU20251890
THYMU20253250
THYMU20255570
THYMU20255720
THYMU20259090
THYMU20265300
THYMU20271250
THYMU20272490
THYMU20277390
THYMU20279750
THYMU20283790
THYMU20284120
THYMU20286290
THYMU20286320
TKIDN10000010//translocase of inner mitochondrial membrane 23
(yeast) homolog//6.30E-67//133aa//98%//NP.sub.--006318
TKIDN20004640//GALACTOKINASE 2 (EC
2.7.1.6).//5.10E-99//200aa//97%//Q01415
TKIDN20005210
TKIDN20030590
TKIDN20030620
[0626] TKIDN20047480//MITOGEN-ACTIVATED PROTEIN KINASE 12 (EC
2.7.1.-) (EXTRACELLULAR SIGNAL-REGULATED KINASE 6) (EC 2.7.1.-)
(ERK6) (ERK5) (STRESS-ACTIVATED PROTEIN KINASE-3)
(MITOGEN-ACTIVATED PROTEIN KINASE P38 GAMMA) (MAP KINASE P38
GAMMA).//2.20E-52//104aa//100%//P53778
TOVAR20004760
TOVAR20005750
TRACH20002870//CLAUDIN-6.//1.30E-27//175aa//42%//Q9Z262
TRACH20003590//CYTOCHROME P450 4A4 (EC 1.14.14.1) (CYPIVA4)
(PROSTAGLANDIN OMEGA-HYDROXYLASE)
(P450-P-2).//1.50E-138//493aa//49%//P10611
TRACH20005020
TRACH20005400//Mus musculus GTPase Rab37 (Rab37) mRNA, complete
cds.//3.30E-109//223aa//93%//AF233582
TRACH20007020//TRICHOHYALIN.//5.60E-24//532aa//23%//P37709
TRACH20016210//ALPHA-(1,3)-FUCOSYLTRANSFERASE (EC 2.4.1.65)
(GALACTOSIDE 3-L-FUCOSYLTRANSFERASE) (FUCOSYLTRANSFERASE 6)
(FUCT-VI).//5.00E-192//254aa//99%//P51993
TRACH20019960//SODIUM/POTASSIUM-TRANSPORTING ATPASE ALPHA-1 CHAIN
PRECURSOR (EC 3.6.1.37) (SODIUM PUMP) (NA+/K+
ATPASE).//9.50E-185//410aa//84%//P05023
TRACH20027840
TRACH20028030//Mus musculus mmDNAJA4 mRNA for mmDj4, complete
cds.//8.50E-205//397aa//92%//AB032401
TRACH20029540
TRACH20032720
TRACH20033230//MALTOSE PERMEASE.//1.20E-10//197aa//23%//Q45632
TRACH20034840//SKIN SECRETORY PROTEIN XP2 PRECURSOR (APEG
PROTEIN).//5.90E-14//342aa//28%//P17437
TRACH20037360
TRACH20041830//Aedes triseriatus putative disulfide-isomerase mRNA,
partial cds.//3.10E-29//134aa//47%//AF306866
TRACH20042920//Human C3f mRNA, complete
cds.//7.80E-195//381aa//89%//U72515
TRACH20048450//PROTEIN K4 (PROTEIN
K3).//4.70E-57//431aa//32%//P18377
TRACH20050040//PUTATIVE SURFACE GLYCOPROTEIN C210RF1 PRECURSOR
(C210RF3).//8.50E-74//177aa//74%//P53801
TRACH20056980
TRACH20057690//RAC-BETA SERINE/THREONINE KINASE (EC 2.7.1.-)
(RAC-PK-BETA) (AKT2 KINASE).//8.80E-22//48aa//100%//P31751
TRACH20060150
TRACH20067620//N-ACETYLLACTOSAMINIDE
BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE (EC 2.4.1.150)
(N-ACETYLGLUCOSAMINYLTRANSFERASE) (1-BRANCHING ENZYME)
(IGNT).//8.20E-76//145aa//92%//Q06430
TRACH20068660//Mouse 19.5 mRNA, complete
cds.//1.00E-55//263aa//41%//M32486
TRACH20068700//Homo sapiens adaptor protein CIKS mRNA, complete
cds.//1.50E-232//572aa//79%//AF272151
TRACH20069180//Homo sapiens IGHG3 gene for immunoglobulin heavy
chain gamma 3 constant region, 4-exon hinge, isolate
Lib-A2.//1.00E-213//377aa//100%//AJ390247
TRACH20076740//FOLATE-LIKE TRANSPORTER DJ206D15.1 ON CHROMOSOME 1
(FRAGMENT).//1.00E-61//276aa//46%//060779
TRACH20076760
TRACH20077540//DXS8237E PROTEIN
(FRAGMENT).//6.00E-96//189aa//95%//P98175
TRACH20079690//ZINC FINGER PROTEIN
136.//1.50E-113//368aa//58%//P52737
TRACH20082780
TRACH20084720//METHIONYL-TRNA SYNTHETASE, MITOCHONDRIAL (EC
6.1.1.10) (METHIONINE-TRNA LIGASE)
(METRS).//8.50E-90//525aa//38%//074634
TRACH20085400//Mus musculus immunoglobulin scavenger receptor IgSR
mRNA, complete cds.//1.30E-89//384aa//47%//AF302046
TRACH20085830//CYTOCHROME P450 4A8 (EC 1.14.14.1) (CYPIVA8)
(P450-KP1) (P450-PP1).//3.70E-247//508aa//87%//P24464
TRACH20091230
TRACH20092680
TRACH20096610//LAMIN A (70 KDA
LAMIN).//1.70E-77//164aa//93%//P02545
TRACH20099340
TRACH20105870//EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA
(EIF-4-GAMMA) (EIF-4G) (EIF4G)
(P220).//9.20E-95//204aa//92%//Q04637
TRACH20107710
TRACH20109650
TRACH20111130
TRACH20115740
TRACH20118940
TRACH20121380//REGULATOR OF G-PROTEIN SIGNALING 14 (RGS14)
(FRAGMENT).//7.60E-144//308aa//92%//043566
TRACH20128110//Rattus norvegicus TM6P1 (TM6P1) mRNA, complete
cds.//2.10E-87//187aa//88%//AF186469
TRACH20128230//Homo sapiens IGHG3 gene for immunoglobulin heavy
chain gamma 3 constant region, 4-exon hinge, isolate
Lib-A2.//9.60E-213//377aa//99%//AJ390247
TRACH20134950
TRACH20135520
TRACH20136710//IG LAMBDA CHAIN V-II REGION
NIG-84.//2.20E-43//112aa//75%//P04209
TRACH20139820//SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN
(SRP68).//3.70E-48//107aa//92%//Q00004
TRACH20140820
TRACH20141240//Mus musculus G21 protein mRNA, complete
cds.//6.10E-26//60aa//93%//AF131207
TRACH20145440
TRACH20147250
TRACH20149970//Rattus norvegicus Ca2+-dependent activator protein
(CAPS) mRNA, complete cds.//2.30E-205//512aa//74%//U16802
TRACH20153810
TRACH20154860//RETINOIC ACID RECEPTOR ALPHA
(RAR-ALPHA).//8.90E-221//443aa//92%//P10276
TRACH20162860//NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B (EC
1.6.5.3) (EC 1.6.99.3) (COMPLEX I-B14.5B)
(C1-B14.5B).//1.80E-39//80aa//98%//095298
TRACH20163170//HOMEOBOX PROTEIN
MEISI.//1.50E-131//238aa//100%//000470
TRACH20164980//ZINC FINGER PROTEIN 184
(FRAGMENT).//1.50E-163//488aa//56%//Q99676
TRACH20167220
TRACH20168350
TRACH20169800
TRACH20180840
TRACH20183170//Rattus norvegicus Sprague-Dawley SM-20 mRNA,
complete cds.//1.60E-75//215aa//61%//U06713
TRACH20184490//Homo sapiens mRNA for zinc finger protein (ZNF304
gene).//3.20E-111//477aa//46%//AJ276316
TRACH20187180
TRACH20190240//Homo sapiens mRNA for
fibulin-4.//1.00E-98//179aa//97%//AJ132819
TSTOM10001860
TSTOM20001390
TSTOM20003150
TSTOM20005690//kelch (Drosophila)-like 3 [Homo
sapiens]//5.60E-211//399aa//98%//NP.sub.--059111
TUTER20002830//Homo sapiens transformer-2-beta (SFRS10) gene,
alternatively spliced products, complete
cds.//4.70E-122//253aa//90%//AF057159
UMVEN10001560//Anthocidaris crassispina mRNA for outer arm dynein
light chain 1, complete cds.//1.90E-24//119aa//47%//AB010055
UMVEN10001860//N-CHIMAERIN (NC) (N-CHIMERIN) (ALPHA CHIMERIN)
(A-CHIMAERIN).//5.90E-25//180aa//33%//P30337
UMVEN20000690
UMVEN20003540
UTERU20000740//Human fusion protein mRNA, complete
cds.//4.90E-47//97aa//100%//M82829
UTERU20004240//CGI-96
protein//2.10E-39//108aa//81%//NP.sub.--056518
UTERU20006290
UTERU20006960//endoplasmic reticulum resident protein
58//5.90E-51//150aa//63%//NP.sub.--076994
UTERU20020010
UTERU20022940//Human (p23) mRNA, complete
cds.//2.80E-80//147aa//99%//L24804
UTERU20030570//CHLORIDE CHANNEL PROTEIN CLC-KB
(CLC-K2).//3.00E-252//469aa//99%//P51801
UTERU20040610
UTERU20046640//Mus musculus ldlBp (LDLB) mRNA, complete
cds.//0//839aa//83%//AF109377
UTERU20046980//Mus musculus mRNA for thrombospondin type 1 domain,
complete cds.//7.30E-117//232aa//87%//AB016768
UTERU20050690
UTERU20054460
UTERU20055330
UTERU20055480
UTERU20055930
UTERU20056010
UTERU20059050
UTERU20061030
UTERU20064000
UTERU20064860//GLUCOAMYLASE S1/S2 PRECURSOR (EC 3.2.1.3) (GLUCAN
1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN
GLUCOHYDROLASE).//1.50E-29//595aa//28%//P08640
UTERU20065930//GTP-RHO BINDING PROTEIN 1
(RHOPHILIN).//6.10E-131//489aa//48%//Q61085
UTERU20067050
UTERU20068990
UTERU20070040
UTERU20070810
UTERU20076390
UTERU20081300
UTERU20084260
UTERU20094350
UTERU20095380
UTERU20095400
UTERU20097760//OVCA2=candidate tumor suppressor [human, fetal
brain, Peptide, 120 aa]//6.00E-30//66aa//95%//AAB36422
UTERU20099720//Homo sapiens mRNA for SPIN
protein.//6.50E-72//186aa//79%//Y14946
UTERU20101240
UTERU20114100
UTERU20115740//Human PMS2 related (hPMSR3) gene, complete
cds.//1.00E-43//84aa//98%//U38979
UTERU20116570//Homo sapiens actin-binding double-zinc-finger
protein (abLIM) mRNA, complete
cds.//4.80E-163//468aa//71%//AF005654
UTERU20118110
UTERU20118970
UTERU20119060
UTERU20119680
UTERU20120310//Rattus norvegicus rexo70 mRNA, complete
cds.//1.50E-65//178aa//78%//AF032667
UTERU20124070
UTERU20126880
UTERU20134910
UTERU20135860
UTERU20143980
UTERU20144640//ACID CERAMIDASE PRECURSOR (EC 3.5.1.23)
(ACYLSPHINGOSINE DEACYLASE) (N-ACYLSPHINGOSINE AMIDOHYDROLASE) (AC)
(PUTATIVE 32 KDA HEART PROTEIN)
(PHP32).//1.90E-166//243aa//100%//Q13510
UTERU20145480//Homo sapiens ZK1 mRNA for Kruppel-type zinc finger
protein, complete cds.//4.40E-213//673aa//57%//AB011414
UTERU20146310//DIACYLGLYCEROL KINASE ETA (EC 2.7.1.107)
(DIGLYCERIDE KINASE) (DGK-ETA) (DAG KINASE
ETA).//4.50E-242//485aa//92%//Q64398
UTERU20146680
UTERU20150870
UTERU20151980//DUAL SPECIFICITY PROTEIN PHOSPHATASE 8 (EC 3.1.3.48)
(EC 3.1.3.16) (DUAL SPECIFICITY PROTEIN PHOSPHATASE
HVH-5).//5.20E-15//248aa//31%//Q13202
UTERU20158300
UTERU20158800//P-SELECTIN GLYCOPROTEIN LIGAND 1 PRECURSOR (PSGL-1)
(SELECTIN P LIGAND) (CD162
ANTIGEN).//2.20E-185//384aa//95%//Q14242
UTERU20161570//PROBABLE G PROTEIN-COUPLED RECEPTOR
RTA.//2.70E-141//303aa//85%//P23749
UTERU20164260
UTERU20168220//AIG1 PROTEIN.//7.70E-16//145aa//35%//P54120
UTERU20176130//Mus musculus zinc finger protein 289 (Zfp289) mRNA,
complete cds.//4.00E-143//297aa//94%//AF229439
UTERU20176320//DNA REPAIR PROTEIN
RAD18.//1.10E-40//333aa//32%//P53692
UTERU20178100
UTERU20179880
UTERU20183640//SEMAPHORIN 3B PRECURSOR (SEMAPHORIN V) (SEMA
V).//1.20E-69//135aa//100%//Q13214
UTERU20185230//Human androgen-induced prostate proliferative
shutoff associated protein (AS3) mRNA, complete
cds.//1.90E-255//571aa//80%//U95825
UTERU20186740
UTERU20188110//Rattus norvegicus cytosolic sorting protein PACS-1a
(PACS-1) mRNA, complete cds.//4.10E-157//315aa//97%//AF076183
UTERU20188810
Sequence CWU 0 SQTB SEQUENCE LISTING The patent application
contains a lengthy "Sequence Listing" section. A copy of the
"Sequence Listing" is available in electronic form from the USPTO
web site
(http://seqdata.uspto.gov/?pageRequest=docDetail&DocID=US20060105376A1).
An electronic copy of the "Sequence Listing" will also be available
from the USPTO upon request and payment of the fee set forth in 37
CFR 1.19(b)(3).
0 SQTB SEQUENCE LISTING The patent application contains a lengthy
"Sequence Listing" section. A copy of the "Sequence Listing" is
available in electronic form from the USPTO web site
(http://seqdata.uspto.gov/?pageRequest=docDetail&DocID=US20060105376A1).
An electronic copy of the "Sequence Listing" will also be available
from the USPTO upon request and payment of the fee set forth in 37
CFR 1.19(b)(3).
* * * * *
References