U.S. patent application number 10/792632 was filed with the patent office on 2004-09-02 for medical effect of jojoba oil in the treatment of skin diseases.
This patent application is currently assigned to Egyptian Natural Oil. Invention is credited to Sadek El Mogy, Nabil.
Application Number | 20040170712 10/792632 |
Document ID | / |
Family ID | 8163780 |
Filed Date | 2004-09-02 |
United States Patent
Application |
20040170712 |
Kind Code |
A1 |
Sadek El Mogy, Nabil |
September 2, 2004 |
Medical effect of Jojoba Oil in the treatment of skin diseases
Abstract
In accordance with the present invention Jojoba Oil may be used
in accordance with the treatment of and preventative measures
associated with Gynecology of Obstetrics and general surgery, as
well as in the treatment of eye diseases, inflammation of the
internal, middle or external ear, rheumatic pain and arthritis,
gingivostomatitis, toothache and dermal diseases. Jojoba oil is a
natural product and is characterized by being non-irritant and
non-allergic to skin and mucous membrane. This oil has lubricant,
moisturizing and soothing properties, as well as having
anti-bacterial, anti-inflammatory and anti-oxidant properties. It
has a very high healing power and improves blood circulation, and
also has high penetration into stratum corneum.
Inventors: |
Sadek El Mogy, Nabil; (Nasr
City, EG) |
Correspondence
Address: |
ADAM K. SACHAROFF
MUCH SHELIST FREED DENENBERG AMENT&RUBENSTEIN,PC
191 N. WACKER DRIVE
SUITE 1800
CHICAGO
IL
60606-1615
US
|
Assignee: |
Egyptian Natural Oil
Cairo
EG
South Egypt Drug Industries Co.
Cairo
EG
|
Family ID: |
8163780 |
Appl. No.: |
10/792632 |
Filed: |
March 4, 2004 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
|
|
10792632 |
Mar 4, 2004 |
|
|
|
10189888 |
Jul 3, 2002 |
|
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Current U.S.
Class: |
424/757 ;
424/642; 514/159 |
Current CPC
Class: |
A61Q 17/02 20130101;
A61Q 19/00 20130101; A61Q 11/00 20130101; A61P 13/08 20180101; A61Q
5/004 20130101; A61P 17/02 20180101; A61P 17/06 20180101; A61K
2800/522 20130101; A61P 15/00 20180101; A61P 17/08 20180101; A61P
17/00 20180101; A61P 27/16 20180101; A61P 1/02 20180101; A61P 7/02
20180101; B01D 11/0288 20130101; A61P 29/00 20180101; A61P 19/02
20180101; A61P 19/08 20180101; A61P 17/16 20180101; A61K 8/922
20130101; A61P 31/04 20180101; A61K 36/185 20130101; A61P 9/00
20180101; A61Q 5/006 20130101; A61Q 7/00 20130101; A61Q 19/008
20130101; A61P 37/08 20180101; A61P 31/10 20180101 |
Class at
Publication: |
424/757 ;
514/159; 424/642 |
International
Class: |
A61K 035/78; A61K
033/32 |
Foreign Application Data
Date |
Code |
Application Number |
Jul 7, 2001 |
EG |
750 |
Claims
17. (Currently Amended) A method of treating skin diseases, by
applying a composition that includes Jojoba oil extruded from
Jojoba seeds wherein the extraction of Jojoba oil is prepared by:
pressing a Jojoba seed under pressure from approximately 1 to
approximately 38 tons/inch to obtain a first phase oil, elutriating
said first phase oil for a predetermined amount of time, filtering
said elutriated oil with at least a level four filter creating a
filtered oil, re-elutriating said filtered oil for a predetermined
amount of time creating a re-elutriated oil, and re-filtering said
re-elutriated oil through a at least a level 4 filter.
23. The method of claim 17, wherein the skin diseases include but
are not limited to acne, psoriasis, dandruff, fishskin disease or
Ichthyosis, sebum or excessive exudation of sebaceous glands,
tinea, napkin dermatitis or diaper disease, skin rash, allergic
dermatitis or skin inflammation, inset bites, monilial and nipple
fissure or natural crevices.
28. The method of claim 27, wherein the composition includes
approximately 50% Jojoba Oil by weight and approximately 8% Zinc
Oxide by weight.
25. A method of treating skin diseases, such as but not limited to
acne, psoriasis, dandruff, fishskin disease or Ichthyosis, sebum or
excessive exudation of sebaceous glands, and tinea by topically
applying to the affected area on the human body an effective amount
of a composition comprising at least Jojoba Oil and Salicylic acid.
Description
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a divisional application of U.S. patent
application Ser. No. 10/189,888 and filed on Aug. 3, 2002, which
claims foreign priority to Egyptian Patent Application No. 750 and
filed on Jul. 7, 2001.
FIELD OF THE INVENTION
[0002] The present invention relates to various medical effects of
the Jojoba oil.
BACKGROUND OF THE INVENTION
[0003] Jojoba oil is used in Lubricating motors and added to some
cosmetic preparations. However, such previous uses of Jojoba Oil
are not related to the new uses subjected to this invention.
SUMMARY OF THE INVENTION
[0004] In accordance with the present invention Jojoba Oil may be
used in accordance with the treatment of and preventative measures
associated with Gynecology of Obstetrics and general surgery, as
well as in the treatment of eye diseases, inflammation of the
internal, middle or external ear, rheumatic pain and arthritis,
gingivostomatitis, toothache and dermal diseases.
[0005] Moreover, the Jojoba Oil is preferably extruded in
accordance with the present invention.
[0006] Numerous other advantages and features of the invention will
become readily apparent from the following detailed description of
the invention and the embodiments thereof, from the claims, and
from the accompanying drawings.
DETAILED DESCRIPTION OF THE EMBODIMENTS
[0007] While the invention is susceptible to embodiments in many
different forms, there are shown in the drawings and will be
described herein, in detail, the preferred embodiments of the
present invention. It should be understood, however, that the
present disclosure is to be considered an exemplification of the
principles of the invention and is not intended to limit the spirit
or scope of the invention and/or claims of the embodiments
illustrated.
[0008] Natural Jojoba oil is extracted from seeds of Jojoba shrub
{Simmondsia Chinensis (LINK) Schnieder}. It is made up of straight
chain esters of mono-unsaturated long chain fatty acids and fatty
alcohols and has an average total carbon chain length of 42
carbons, so it is classified chemically as a liquid wax.
[0009] Jojoba oil is composed entirely of esters of high molecular
weight, straight chain mono-ethylenic acids and mono-ethylenic
alcohols. The unsaturated acids are mixture of eicosanoic (C20) and
docosanoic (C22), with small quantities of palmiloleic (C18) and
oleic (C16) acids. The unsaturated alcohols are a mixture of
eicosanol and docosanol, with smaller quantities of hexacosanol and
alcohols of lower molecular weight.
[0010] Jojoba oil is non-volatile and free from rancidity, and this
is attributed in part to presence of tocopherols (natural
anti-oxidant) as a minor constituent and mainly to its wax
structure (It has only one alcohol group, so it is not subject to
oxidation and will never become rancid). Furthermore, researches
showed that Jojoba oil possesses the six general factors which
increase permeation into stratum cornium:--low viscosity, high
unsaturation, low saponification number, short carbon chain length,
low lecithin (Jojoba oil has no lecithin), straight chain molecule
and branched esters.
[0011] Jojoba oil helps to avoid the two important causes of
premature aging of the skin:--dryness and lipid perioxidation. It
serves as an excellent non-occlusive moisturizing agent that
enhances the flexibility and suppleness of the skin. At the same
time, its exceptional non-tacky spread and lubricity leave a rich
velvety after-feel.
[0012] Jojoba oil is characterized by having 50% of its content as
insaponifiables (Triterpene alcohols and Phytosterols) while other
vegetable oil contain only 2-3%. Moreover applying insaponifiables
to skin increases elastin formation, which in turn increases skin
luster, elasticity and integration. Jojoba Oil also provides skin
protection as it has anti-allergic properties, disinfectant, and
produces cell stimulation, skin regeneration and stops
inflammation. The pH of Jojoba oil is balanced and reveals
beneficial effects for dry and damaged skin.
[0013] Jojoba oil is also proven to have anti-inflammatory and
anti-microbial effects as well. Five of the most common bacteria
including staphylococcus aureus and pseudomonas aeruginosa as well
as fungus candida albicans are not able to grow in Jojoba oil.
[0014] One novel way to extract the Jojoba Oil from the Jojoba
seeds is as follows. First, it has been determined that the Jojoba
seeds contain 50-55% of its weight oil. The Jojoba oil is extracted
in phase one by pressing the Jojoba seeds under pressure reaching
gradually from 1 to 35-38 Ton/Inch. About 26-28% oil from the seeds
weight is obtained form the first pressing phase, also called phase
one oil, which may be used for medical application. After
separating the phase-one oil from the crashed seeds, the residual
squeezed seeds are pressed again under pressure up to 100 Ton/Inch,
which extracts second phase oil, which may be used in cosmetic and
other fields. Also called second phase oil. Independently, the
first-phase-oil and second-phase-oil are elutriated for certain
time. The elutriated oils are then passed through 4-level filter
and again elutriated for a predetermined time. The oils are
refiltered through 4-level filter and a higher than the first
4-level filter, to obtain the final oil for use. The extracted oil
in the first phase is superior to the ordinary oil especially in
the medical effect.
[0015] The extracted Jojoba oil is effectively used in the
treatment of the following:
[0016] Dermal Diseases:
[0017] It has been effectively used with salicylic acid in the
treatment of psoriasis, dandruff, acne and fish skin disease. It
has been effectively used with zinc oxide in the treatment of
napkin dermatitis, skin rash, allergic dermatitis and monilial
infection. It has been effectively used with the treatment of
insect bites and the treatment of fungal infect in toes. It is
effective in protecting skin from non-infective allergic materials
such as liquid washing soap. It has been effectively used in
treatment of mange, treating first degree burns and sun burns as
well as protecting skin from hazards of ultra violate rays during
sun-tanning. It is also elective as a first aid for wounds and
treating inflammatory wounds and enhancing healing by primary
intention. It is effective in the treatment of bedsores. It has
been used in assisting treatment of alopecia areata and rogenetica.
It has been used to eliminate hair lice. It has been effectively
used in treatment of Herpes simplex labialis (cold sores). It has
also been effectively used in healing diabetic wounds especially
diabetic foot.
[0018] Treatment of Gingivostomatitis and Toothache:
[0019] The extracted Jojoba oil has been effectively used with
lidocaine in the treatment of recurrent aphthous ulceration. It has
been used in toothpaste to treat gingivitis and improve the
circulation of gingiva. It has been effectively used with zinc
oxide in temporary filling. It has also been effectively used in
the treatment of the dry socket as a side effect of chemotherapy
and radiotherapy.
[0020] Rheumatic Pain and Arthritis:
[0021] The Jojoba Oil is effective in treating and reliving pains
of polyarthitis, rheumatic pains, arthralgia, and spondylitis. It
is effective in enhancing the effect of physiotherapy and
supporting body to regain its physical ability in addition to
eliminating the stress and cramps.
[0022] Inflammation of the Ear
[0023] It has been effective in treatment of otitis externa and
otitis media.
[0024] Treatment of Eye Diseases:
[0025] It has been effectively used in treatment of thrombosis.
[0026] General Surgery:
[0027] It has been effectively used as suppositories in treatment
of acute and chronic anal fissure and anal fistula, as well as the
treatment of prostatits, Hiemorroids (at 2.sup.nd degree) and early
stages of Varicose Vein.
[0028] Gynecology of Obstetrics:
[0029] It has been effectively used as a Vaginal suppository in
treatment of vaginitis, used in reliving the pain accompanied with
dysmenorrhoea, and used in the treatment of nipple crakes and
improve its healing.
[0030] The Method of Use
[0031] The Jojoba oil is used by being added to other medicines,
for achieving better effects of the novel medicine without any side
effects. Examples are as following:
[0032] 1--10% of Jojoba oil by weight, and 0.5% of Lidocaine
hydrochloride by weight are used for treating the inflammation of
mucous membrane of mouth and condition resulted form administration
of antibiotics for long time.
[0033] 2--50% of Jojoba Oil by weight, and 2% salicylic acid by
weight are used in ointment form for treating acne, psoriases,
dandruff, sebum (abnormal excessive exudatation of sebaceous glands
in skin) and fish skin disease (Thick epidermis being tough and
continually scalling)
[0034] 3--50% of Jojoba oil by weight with 8% of zinc oxide weight
can be used in treating conditions of skin rash and allergic
dermatitis.
[0035] 4--As suppository contain, 20% of Jojoba oil by weight can
be used to treat the anal fissure.
[0036] 5--Vaginal suppository containing 20% of Jojoba oil by
weight can be used in treating non-infective vaginitis.
[0037] Jojoba oil is extracted by pressing the crashed seeds
gradually under pressure form 1 to 35-38 Ton/Inch to obtain first
phase oil, then meal well be crashed again and pressed under
pressure up to 100 Ton/Inch to obtain second phase oil, then each
type of oil will go through different levels of filtration, since
the first phase oil is used for medical application for treating
many illnesses.
[0038] As mentioned previously, from seeds, Jojoba oil and its
derivatives are extracted including straight chains of
mono-ethylenic acids and mono ethylenic alcohols; further more
Jojoba oil is non-volatile, not subject to oxidation and not liable
to rancidity in addition to its high penetrability to skin as a
result of its low viscosity, high unsaturation, low saponification
number, short carbon chain length, low lecithin, straight chain
molecule and branched esters.
[0039] As motioned previously, the Jojoba oil is used as
anti-bacteria, skin protective, anti-allergic, anti-inflammatory,
anti-fungal, improving wound healing and blood circulation in the
skin.
[0040] As mentioned previously, Jojoba oil as an essential element,
is used for treating many dermal diseases.
[0041] As mentioned previously, Jojoba oil is used as an essential
element, in the treatment of the inflammation of mucus membrane of
the mouth, temporary filling and dry sockets.
[0042] As mentioned previously, Jojoba oil is used as a main
element in treating and reliving pains of polyarthitis, rheumatic
pains, arthralgia, and spondylitis.
[0043] As mentioned previously, Jojoba oil is used as a main
element, for treating otitis externa and otitis media.
[0044] As mentioned previously, as a main element, Jojoba oil is
used in treatment of thrombosis.
[0045] As mentioned previously, as a main element, Jojoba oil is
used in treatment of some general surgeries such as anal fissure,
anal fistula, prostatits, and Hiemorroids (at 2.sup.nd degree).
[0046] As mentioned previously, Jojoba oil is used as a main
element in treatment of vaginitis, and nipple crakes in addition to
reliving the pain accompanied with dysmenorrhoea.
[0047] As mentioned previously, compound contain 10% of Jojoba oil
by weight and 0.5% of lidocaine hydrochloride by weight, is
particularly effective in treating mouth ulcer and
gingivostomatitis and removing the erythena in addition to reducing
Edema associated to these inflammations--this effect returns to the
Jojoba oil properties as anti-bacterial and anti-inflammation
substance. Also, the Jojoba oil acts as a painkiller for the
conditions. Some of the Jojoba oil's indications are:
gingivostomatitis and conditions resulted from using antibiotics
for long time. Moreover, this compound has no side effects.
[0048] As mentioned previously, preparation contains 50% of Jojoba
oil by weight and 2% of salicylic acid by weight and is used for
treating acne, psoriasis dandruff sebum (abnormal) excessive
exudatation of seba ceous glands in skin and fish skin disease; it
could also be used in treatment of fungal infection as tinia
(tinea). This preparation also has no side effect.
[0049] As mentioned previously, a suppository containing 20% jojoba
oil by weight can be used to treat the anal fissure. It could
relieve the intensity of pains and the complications in many
patients as well as eliminating pills. Moreover, this suppository
has no side effects.
[0050] As mentioned previously, ointments containing 50% of Jojoba
oil by weight with 8% of zinc oxide by weight used in treating
condition of rash, napkin dermatitis, skin inflammation, insect
bytes, monilyases, and nipple fissure, no side effects have been
resulted from this preparation.
[0051] As mentioned previously, a vaginal suppository containing
20% Jojoba oil by weight is used to eliminate the vaginitis (acute
or recurrent). This suppository has no side effects.
[0052] Form all the above mentioned benefits, it becomes clear that
Jojoba oil, in its all forms and cases, all the illnesses treated
with it, has not any side-effects on the human body or
environment.
[0053] From the foregoing and as mentioned above, it will be
observed that numerous variations and modifications may be effected
without departing from the spirit and scope of the novel concept of
the invention. It is to be understood that no limitation with
respect to the specific methods and apparatus illustrated herein is
intended or should be inferred. It is, of course, intended to cover
by the appended claims all such modifications as fall within the
scope of the claims.
* * * * *