U.S. patent application number 10/451651 was filed with the patent office on 2004-08-26 for piece of jewelry bearing a genetic fingerprint.
Invention is credited to Olek, Alexander.
Application Number | 20040163412 10/451651 |
Document ID | / |
Family ID | 7669040 |
Filed Date | 2004-08-26 |
United States Patent
Application |
20040163412 |
Kind Code |
A1 |
Olek, Alexander |
August 26, 2004 |
Piece of jewelry bearing a genetic fingerprint
Abstract
Described are decoration objects, that are intended to be worn
by an individual and characterized in that they carry genetic
information about the individual wearing the decoration object, or
about a different individual. In a preferred embodiment these
decoration objects are wedding rings or engagement rings.
Inventors: |
Olek, Alexander; (Berlin,
DE) |
Correspondence
Address: |
Kriegsman & Kriegsman
565 Franklin Street
Framingham
MA
01702
US
|
Family ID: |
7669040 |
Appl. No.: |
10/451651 |
Filed: |
March 4, 2004 |
PCT Filed: |
December 21, 2001 |
PCT NO: |
PCT/DE01/04963 |
Current U.S.
Class: |
63/3 |
Current CPC
Class: |
A44C 9/00 20130101; A44C
5/0015 20130101 |
Class at
Publication: |
063/003 |
International
Class: |
A44C 005/00 |
Foreign Application Data
Date |
Code |
Application Number |
Dec 21, 2000 |
DE |
100 65 089 |
Claims
1. Decoration object that is determined to be worn by an
individual, characterized in that it carries information about
another individual, and characterized in that the decoration object
is a ring, a wedding ring, a engagement ring, a friendship ring, a
chain, a medallion, a bracelet or combinations thereof.
2. Set of devices according to claim 1, characterized in that the
devices carry the genetic fingerprint of a least two individuals,
whereas the decoration object, that is determined to be worn by a
particular individual, that contains the genetic fingerprint of the
respective other individual and characterized in that the
decoration object is a wedding ring, a engagement ring or a
friendship ring.
3. Decoration object, characterized in that it contains the genetic
fingerprints of the parents of an individual.
4. Decoration object according to claim 3, characterized in that it
is an mug, a plate, cutlery, insignia or another decoration object
that is customary as a birth present.
5. Decoration object according to claim 3, characterized in that it
is a mug, a plate, cutlery, badge or another decoration object that
is customary as a baptism related present.
6. Decoration object according to any of the preceding claims,
characterized in that the genetic fingerprint of the individual is
based on microsatellite markers, single nucleotide polymorphisms
(SNPs) or other genetic markers that are useful for the unambiguous
identification of individuals.
7. Decoration object according to any of the preceding claims,
characterized in that the genetic fingerprints are displayed in the
form of letter and/or syllable and/or word and/or number
combinations, that correspond to the respective standards in
Genetics, or as reliefs, in the form of tables or abstract art.
8. Decoration object according to any of the preceding claims,
characterized in that the genetic information displayed on it is
encoded.
9. Decoration object according to any of the preceding claims,
characterized in that the genetic information can be used with a
more than 99% confidence for the identification of the individual
the information is derived from.
10. Decoration object according to any of the preceding claims,
characterized in that the major function is not decoration, but the
possibility for identification.
11. Method to attach genetic information to an decoration object
and to retrieve the same from it, characterized in that the
following steps are carried out: a) the genetic information is
obtained from samples taken from said individuals; b) the genetic
information is encoded, and the key to this code is stored at a
person or an institution, that is not allowed to pass on this key
without authorization by a group of persons previously determined;
c) the encoded information is attached to the decoration object d)
in case, that the genetic information is required for
identification, it is retrieved from the (encoded) information on
the decoration object and the key provided by said person or
institution in case of qualified interest.
12. Method according to claim 11, characterized in that the
attachment of the genetic information to the device is conducted in
the form of letters and/or syllables and/or word and/or number
combinations, that correspond to the respective standards in
Genetics, or as reliefs, in the form of tables or abstract art.
Description
FIELD OF THE INVENTION
[0001] The invention is related to marking jewelry with genetic
fingerprints of individuals.
STATE OF THE ART
[0002] For establishing the classical genetic fingerprints, the
whole DNA of an individual, in one or more of the possible types,
is divided into smaller fragments, typically by means of a
so-called restriction endonuclease. These fragments are separated
according to the lengths of the fragments using gel
electrophoresis. Within many of the resulting fragments there are
so-called repeats, repetitions of one and the same base sequence,
and the number of repetitions varies between different individuals.
A labelled probe composed of a DNA sequence that is complementary
to the repeat can be hybridized and simultaneously the length of
many of such repeats can be visualized. The resulting pattern is
with very high likelihood unique for each human being. As the
length measurements of the different pieces of DNA are only
relative (within one separation), in each of such experiments
so-called standards have to be used that provide for the
comparability--and thus also the actual uniqueness--of the
[genetic] fingerprint.
[0003] The variant of the genetic fingerprint that is preferred
today is the [analysis of] so-called microsatellites. These also
are comprised of repeats of either two or four bases (the most
common type is the CACACACA repeat), and the number of repetitions
per repeat can vary.
[0004] The genetic markers, each single one of which can be present
in more than only two variants, are defined by the unique DNA
sequences flanking them on both sides.
[0005] The biggest advantage of these markers is, that in
world-wide sets of experiments a defined set of such markers was
established and is now accepted internationally. Also, one has
agreed on one [commonly] accepted number and letter code, that
sufficiently describes the information [contained in] the
individual markers.
[0006] The future method to determine the identity will probably be
the detection of single variable base exchanges of the human DNA.
Statistically, about every 100 or 1000 bases (the exact frequency
is still unknown and not important in this context) within the
human genome there is one position, at which there is the one base
in a part of the [human] population, but in another part of the
population another base is located at the same position. If such a
variability is very small (only the by far smallest part of the
population has the one base, while in the vast majority there is
the other one), this is classically referred to as a mutation. With
a certain distribution of the bases that are possible at a given
position being more equal, this is referred to as a polymorphism or
SNP. One can now calculate that in an analysis of an individual,
starting from a certain number of such SNP positions, the sum of
identities at the analysed positions will yield a unequivocal
description of said individual. There are hundred-thousands of such
SNPs in the human genome and today people world-wide have not yet
agreed on a combination that would be generally valid for all such
analyses. There is also no accepted addressing system for SNPs in
the human genome (besides the description of the actual sequence
context), and some ten positions would have to be used for the
unequivocal description of an individual. As soon as a standard set
of such markers will exist, however, there is no doubt that there
will also be an internationally accepted number or letter code (or
any other encoding). Possibly the characterisation of SNPs for the
unambiguous determination of identity will also be the method of
choice in the future.
[0007] Typically, when decoration objects, ornaments or other
luxury goods are exchanged or a present is made, the relationship
between the donating person and the person receiving the gift is of
primary importance, opposite to many other types of objects, that
may be given as presents. But also the unambiguous labelling of
objects (in own possession) in a highly individual, but appealing
manner is forever since an existing topic, be it because if
individualism or just securing property reasons or a combination of
both.
[0008] Especially when wedding rings are exchanged, such a
labelling is customary, and they normally carry the name or the
given name of the partner, and possibly the wedding date. Today
almost all members of the western societies increasingly appreciate
an exceptional and individual touch in all very personal affairs,
including the exchange of wedding rings or or similar decoration
objects which is again a special case thereof. The individuality of
a ring itself can only be gradually influenced, mainly however
though the price, in the form of the chosen materials of the brand
names of jeweller or a jewellery chain. This method for the
distinction of the decoration objects from the presents of an
unknown person is not possible for most persons alone because of
their limited spending capacity. Additionally, even if there is a
tailor made decoration object made from most distinguished
materials is chosen, the donating person is mostly less linked to
the decoration object than wanted by most individuals.
[0009] The closest state of the art to this invention is considered
to be U.S. Pat. No. 4,993,472, that describes the imprinting of
fingerprints of individuals onto decoration objects. It is to be
considered here, however, that it is usually not possible to place
a full fingerprint of an individual for example on the surface of a
wedding ring. It is a general problem, that the space on the inner
side of a wedding ring is mostly extremely limited, and an
unlimited amount of information about the identity of the donating
person cannot be made.
[0010] Ideally, many brides and grooms for example would like to
demonstrate an extensive exchange of their most personal domains.
Therefore, for the gravure of a wedding ring only stampings or
imprints can be chosen that are not changeable, are linked in an
inseparable manner to a person and have not been donated from
others before. Not even gravures displaying an American Social
Security Number fulfil all these criteria, although the exchange of
this number that is inseparably linked to the people living in the
USA has certainly already been implemented. Also a combination of
surname and given name, date of birth etc would seem to be to
bureaucratic because of the amount of the data, to prevail in
practice.
OBJECT OF THE INVENTION
[0011] The underlying problem that is solved by this invention is,
that it corresponds to the needs of many people, to identify
themselves or other persons in a unique manner on decoration
objects. This occurs, for example, on wedding rings, typically in a
way that their initials or full names are used. However, because of
only the name it is usually impossible to identify the owner of
such a ring. Also, may combinations of given names and surnames are
very abundant, thus the identification of the owner of such an
decoration object is only possible with substantial efforts. Often,
if the names are common, it is not possible with reasonable efforts
to identify the owner. Especially for expensive decoration objects,
however, there is considerable demand [to be able to do so].
[0012] Adding to this practical problem is the increasing
individuality needs in today's society as described above. For the
reasons mentioned, this demand is not always sufficiently met by
applying the name to the decoration object.
DESCRIPTION
[0013] In the following we describe one favourable and some more
technical solutions to the problem described above. The solution is
the attachment of a sum of data points derived from the genome (the
DNA) to the decoration object (for example, engraved into a wedding
ring), that are, taken together, that unique, that with highest
probability there is no other individual existing world-wide who
would have the exact same combination of data points.
[0014] The invention solves the problem by way of employing genetic
fingerprints for the identification of individuals on decoration
objects, as in principle known in the art. For this purpose, the
genetic fingerprints are encoded and printed, for example, into a
wedding ring. This does not only allow for the instant
identification of the rightful owner, but also they are naturally
highly individual. Depending on the effort, it is also possible
with the highest possible security to determine, that the
respective genetic fingerprint is world-wide unique.
[0015] Additionally the stamping allows for a certain theft
protection, as the original owner of the decoration object can be
re-identified any time, unless the decoration object had been
altered or the unique signature had been removed. Such
identification features are known from other high priced devices,
like for example motorized vehicles.
[0016] Subject of this invention is a decoration object, that is
intended to be worn by an individual, carrying genetic information
about an individual. In a particularly preferred embodiment the
decoration object carries the genetic fingerprint of the individual
rightfully wearing it. It can, however, also be the genetic
fingerprint of a different individual. This is especially the case
if decoration objects are exchanged between two individuals. It is
especially preferred that the decoration objects are a ring, a
wedding ring, an engagement ring, a friendship ring, a bracelet, a
medallion, an bracelet or a combination thereof.
[0017] Subject of this invention is also a set of decoration
objects. The decoration objects carry the genetic fingerprints of
at least two individuals, and they are characterized in that the
respective decoration object that is determined to be worn by an
individual contains the genetic fingerprint of the respective other
individual. It is also possible and preferred, that the decoration
objects as a component of a set of at least two decoration objects
each carry the genetic fingerprints of two individuals. In this
respect, a set of wedding rings, engagement rings or friendship
rings is particularly preferred.
[0018] Subject of this invention is further an decoration object
that contains the genetic fingerprints of the parents of an
individual. In this respect, it is particularly preferred that the
decoration object is a plate, mug, cutlery or insignia or any other
decoration object that is customary as a baptism related
present.
[0019] As the underlying information for the genetic fingerprints
microsatellite markers, single nucleotide polymorphisms (SNPs) or
other genetic markers that are useful for the unambiguous
identification of individuals are possible. According to present
knowledge in particular microsatellite markers and in the future
also single nucleotide polymorphisms are especially useful and
therefore preferred.
[0020] The oldest, maybe also best known form of a sum of data
points, that are suitable for the printing on decoration objects,
is the classical genetic fingerprint. In this case, the whole DNA
of an individual, in one or more of the possible types, is divided
into smaller subfragments, typically by means of a so-called
restriction endonuclease. These fragments are separated according
to the lengths of the fragments using gel electrophoresis. Within
many of the resulting fragments there are so-called repeats,
repetitions of one and the same base sequence, the number of which
varies between different individuals. A labelled probe composed of
a DNA sequence that is complementary to the repeat can be
hybridized and simultaneously the length of many of such repeats
can be visualized. The resulting pattern is with very high
likelihood unique for each human being.
[0021] Such a pattern (or an excerpt of it that is sufficient
accurately describing the individual) can now be imprinted or
engraved into a ring, for example, in a graphical format. Because
the length measurement of the different DNA fragments is only
relative (within one such separation), however, in each of such
experiments so-called standards have to be used that provide for
the comparability--and thus also the actual uniqueness--of the
[genetic] fingerprint. To enable a fingerprint describing an
individual accurately, it may therefore be required to also to
attach such a standard to, for example, a ring.
[0022] In case the sum of the relative distances (lengths) of the
DNA fragments only characterizes the individual unambiguously, at
least the challenge concerning the technical precision is that
severe, that these minimal differences are reproduced. This is an
extremely difficult undertaking in that also the size of the
gravure shall vary. Thus, the attachment of a classical genetic
fingerprint to a wedding ring, for example, is a possible, but not
the favoured solution to the problem to be solved.
[0023] The future method to determine the identity will probably be
the detection of single variable base exchanges of the human DNA.
Statistically, about every 100 or 1000 bases (the exact frequency
is still unknown and not important in this context) within the
human genome there is one position, at which there is the one base
in a part of the [human] population, while in another part of the
population another base is located at the same position. If such a
variability is very small (only the by far smallest part of the
population has the one base, while in the vast majority there is
the other one), this is classically referred to as a mutation. With
a certain distribution of the bases that are possible at a given
position being more equal, this is referred to as a polymorphism or
SNP.
[0024] For purposes of the present invention, the most suitable
polymorphism with two possible bases at a given position is the one
with both bases each being present in exactly one half of the
population.
[0025] One can now calculate that in an analysis of an individual,
starting from a certain number of such SNP positions, the sum of
identities at the analysed positions will yield an unambiguous
description of said individual. There are hundred thousands of such
SNPs in the human genome and today people word-wide have not yet
agreed on a combination [of these], that would be generally valid
for all such analyses. As there is also no accepted addressing
system for SNPs in the human genome (besides the description of the
actual sequence context), and some ten positions would have to be
used for the unambiguous description of an individual, a realistic
display in an appealing but unambiguously readable form is still
technically hard to implement on the limited surface of an
decoration object, for example a wedding ring.
[0026] As soon as a standard set of such markers will exist,
however, there is no doubt that there will also be an
internationally accepted number- or letter code (or any other
encoding), that then will also be useable as an appealing gravure.
Possibly the characterisation of SNPs for the unambiguous
determination of identity will also be the method of choice in the
future and therefore will be employed also for the gravure or
stamping of jewellery or other gifts.
[0027] Is the variability of the DNA not based on an exchange of a
single base by another one (or, at most, by the three other
possible ones), but on the exchange of several contiguous bases at
the same position in the genome or the loss of the insertion of
bases in only some individuals, the prediction concerning the
identity is the same, but technical feasibility of the analysis
will be more complicated. There is no agreement about a possible,
unique addressing of such markers, but such a procedure is still to
be considered part of this invention.
[0028] It is however a possible variant of the invention, and this
of course applies to all the mentioned methods of engraving, that
the giving persons prefer not to leave gravures that are clearly
readable for all unauthorized people. In the opposite, for many
people it will sufficient to know (to fulfil their individualism
needs) that the pattern was derived from their genome in a unique
manner. It is also possible that the person would want an
identification of his identity to be absolutely impossible based on
the gravure, but that it can be distinguished from the identity of
another person any time, if only the method for the generation of
the genetic fingerprint was known. It is also possible that [the
identification of] a person, the fingerprint of whom in the form of
a gravure characterized an object is only possible by means of a
code that is stored at a confidential location. For a SNP diagram,
for example, the bases could be engraved, the identity of the
positions in the genome, however (for example by way of the
sequence context) could be deposited at a notary, a bank, the
laboratory producing the fingerprint or even at the jeweller. Of
course, it is also conceivable to encode the sequence context by
means of a cryptographic algorithm and storage on a chip or a
separate computer. It is however more likely that in the future a
high amount of medical data will be story centrally or in a
distributed way, thus also the sequence contexts of the SNPs used
for the fingerprint or generally the identity of other genetic
markers could be stored relying the given confidentiality in this
case. The spectrum of possibilities for the storage of such
information is practically unlimited today. It however assumed that
the form of storage of information does pertain to the major
subject of the invention and that this invention will therefore
include also other forms of the transfer and storage of important
information in this context.
[0029] The encoding of the fingerprints (regardless of the
technical method used, be it in a standardized or discrete form) is
preferably converted into an especially appealing format,
individually or as a limited edition or even a mass product by an
artisan or graphically skilled person (or a similarly acting
designer, jeweller or similar). Certainly the simple number or
letter code, that already exists for microsatellites and that will
likely be available for SNPs soon, will not be the preferred format
for the gravure for a decoration object. In the opposite, the value
and the individuality and thus the exclusivity of a such labelled
present could be significantly enhanced by the conversion of such
number or letter codes into appealing patterns by well known
artisans. This way a well known artisan could, by manufacturing a
unique pattern (it is not relevant in each of the variants whether
the absolute information is readable for each and every person, or
whether the used encoding procedure--as the graphical
representation could be an encoding variant as well--remains
discretely in the possession or availability of a limited circle of
persons or, is deposited confidentially or even is destroyed),
create extreme values in the form of single objects that are
world-wide, in several respects, unique. Also limited editions
that--for example are contracted by jewellery chains to known
artists or designers or could be established on their own--are sold
in larger series, could still satisfy the mentioned individuality
need and even could emphasize the individuality aspect.
[0030] It is possible and of course within the scope of the
invention to introduce standards for the labelling of decoration
objects, or even the introduction of a standard encoding system,
that generally protects the objects by labelling with an own
genetic fingerprint, this identity however is only readable under
defined conditions (or even by law) for other persons.
[0031] In principle, even an absolutely secure signature for the
labelling of objects could be created this way.
[0032] The described methods are the three important, but not the
only ones to derive an individual gravure or imprint for decoration
objects or other presents or even for the labelling of own
property. We would like to emphasize that these are only the most
likely examples for such a labelling. Any possible way to retrieve
information out of the human genome (also, for example, expression
patterns in a particular cell type or protein expression patterns
or other highly individual parameters) and to attach this
information in the form of a engraving, imprint or print for the
labelling of presents, in particular wedding rings, but also
generally properties, is meant to be within the scope of the
present invention. Also the different ways to attach a unambiguous
genetic description of an individual to an object, is of low
importance with respect to the spirit of this invention. These
embodiments include prints, imprints, gravures, reliefs, paintings,
3 dimensional work, millings, bore holes or any other methods to
attach signs to materials. But also the facets of a jewel could in
this context, using (open or discrete) standards take over the role
of an encoding of a genetic fingerprint.
[0033] Also the kind of the material in this context is not
relevant for the spirit of this invention. In principle, even not
very durable presents or gifts like, for example, pralines with
genetic fingerprints are conceivable and are a good [technical]
solution for the permanent problem of finding an individualized
present.
[0034] But it essentially is in the spirit of the invention that as
durable materials as possible are equipped with a durable
labelling. Certainly, gold, white gold or platinum would be most
frequently used for wedding rings, but also a gravure or jewel
would be possible. For example, at the higher end the facets of a
diamond could describe a genetic marker each.
[0035] Normally the genetic fingerprints that are established
today, are not optimized towards a compact display that would be
suitable for smaller decoration objects. Particularly preferred is
the display of the genetic fingerprints in the form of a letter
and/or syllable and/or word and/or number combinations or as
relief, in the form of tables or abstract art.
[0036] The variant of the genetic fingerprint that is preferred
today is the [analysis of] so-called microsatellites. These also
are comprised of repeats of either two or four bases (the most
common type is the CACACACA repeat), and the number of repetitions
per repeat can vary.
[0037] The genetic markers, each single one of which can be present
in more than only two variants, are defined by the unique DNA
sequences flanking them on both sides. As there are multiple
variants of each of the markers, the prediction power of each
marker about the identity of an individual is much higher, as the
one of a particular SNP alone. The biggest advantage of these
markers is, that in world-wide sets of experiments a defined set of
such markers was established and is now accepted internationally.
Also, one has agreed on one [commonly] accepted number and letter
code, that sufficiently describes the information [contained in]
the individual markers. It is therefore very simple to display in a
well-defined way the either eight or twelve used markers by means
of a gravure, even be it as a graphically little appealing
numbering code.
[0038] In a particularly preferred embodiment of the invention, the
genetic information attached to the decoration object is
encoded.
[0039] For persons which prefer an unrestricted readability and
high individuality at an acceptable price, these markers in an open
(standard encoded) form are the gravure or imprint variant of
choice. Persons that prefer an encoded uniqueness, can now choose
any procedure, simple (for example by exchange of the order of the
letters or numbers), or complicated (by use of cryptography), to
confound the unambiguous readability. Of course also a complete
anonymization by destruction of the code is again possible.
[0040] In a particularly preferred embodiment of the invention, the
genetic information attached to the decoration object can be used
with a more than 99% confidence for the identification of the
individual the information is derived from.
[0041] There are also cases where the identification of a person is
already, for example via a chain worn by them, an essential
function of the same, like it is the case with soldiers. It is
assumed for one embodiment of the invention, that the use of
genetic fingerprint as proposed here can also be equivalently
employed for such purposes. In another preferred embodiment of the
invention the major function of the decoration object is not to be
decorative, but the possibility to identify the individual wearing
the decoration object.
[0042] Further embodiments could in the future include such genetic
markers into the engraving, that describe special personal
properties of the donating or the person to which a present was
made. So it seems possible to attach the blood type, eye or hair
colours, in the form of genetic markers to a piece of property,
decoration object or present.
[0043] Subject of this invention is also a method for the
attachment of genetic information to an decoration object and to
the retrieval of the same. Mainly, this method shall ensure that
the genetic information that is attached to the decoration object
cannot be immediately used by unauthorized persons.
[0044] In the first step, as generally known to the person skilled
in the art, the genetic information is retrieved from samples
derived from said individuals.
[0045] In the second step the genetic information is encoded, and
the key to said code is stored at a person or an institution, that
is not authorized to distribute the key without consent of a circle
of persons that has previously been determined. Usually, only the
individual himself or close relatives will belong to this
circle.
[0046] In the third step of the method the encoded information is
attached to the decoration object. This can be conducted either in
the form of a letter and/or syllable and/or word and/or number
combinations, or as reliefs, in a table format or in an
artificially abstract manner, with different techniques like
imprinting, engraving or etching.
[0047] In the last step of the method, in case the genetic
information is required for identification, the information is
derived from the information on the decoration object and from the
key made available by said person or institution in case of a
justified interest.
* * * * *