U.S. patent application number 10/663690 was filed with the patent office on 2004-04-01 for press-through pack, sealing sheet for press-through pack, and preparation method of tablet.
This patent application is currently assigned to KYOWA HAKKO KOGYO CO., LTD.. Invention is credited to Hayakawa, Eiji, Ito, Kunio, Miura, Shigemitsu, Miyabe, Junichi, Oota, Toshiyuki, Yotsuya, Yoichiro.
Application Number | 20040060845 10/663690 |
Document ID | / |
Family ID | 17477998 |
Filed Date | 2004-04-01 |
United States Patent
Application |
20040060845 |
Kind Code |
A1 |
Ito, Kunio ; et al. |
April 1, 2004 |
Press-through pack, sealing sheet for press-through pack, and
preparation method of tablet
Abstract
A press-through pack and a sealing sheet for use in the same
capable of easily taking out solid material such as tablet or the
like contained storage recesses by only pushing action of fingers.
The pack comprises an accommodation body (2) with plural storage
recesses (2a) defined by sheet like portions (2b) for a containing
solid material therein and sealing sheet (5). The sealing sheet (5)
is made of such material that a recess (2a) in which solid material
(T) contained, is partly ruptured without causing floating and
peeling at the adhesion portion of the adhesive layer (4) and the
sheet like portions (2b) when pushing the projecting portion (2c)
of the outer side of the recess (2a) with fingers, whereby the
solid material (T) contained in the recess (2a) is easily taken out
and the sealing sheet is partially bonded to the accommodation body
at sheet like portions (2b) in a manner that the whole parts of
sealing sheet (5) is easily peeled off from the accommodation
body.
Inventors: |
Ito, Kunio; (Sunto-gun,
JP) ; Hayakawa, Eiji; (Sunto-gun, JP) ; Miura,
Shigemitsu; (Susono-shi, JP) ; Miyabe, Junichi;
(Susono-shi, JP) ; Oota, Toshiyuki; (Osaka-shi,
JP) ; Yotsuya, Yoichiro; (Osaka-shi, JP) |
Correspondence
Address: |
FITZPATRICK CELLA HARPER & SCINTO
30 ROCKEFELLER PLAZA
NEW YORK
NY
10112
US
|
Assignee: |
KYOWA HAKKO KOGYO CO., LTD.
Tokyo
JP
|
Family ID: |
17477998 |
Appl. No.: |
10/663690 |
Filed: |
September 17, 2003 |
Related U.S. Patent Documents
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Application
Number |
Filing Date |
Patent Number |
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10663690 |
Sep 17, 2003 |
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09539701 |
Mar 31, 2000 |
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6637596 |
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09539701 |
Mar 31, 2000 |
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PCT/JP98/04452 |
Oct 1, 1998 |
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Current U.S.
Class: |
206/530 |
Current CPC
Class: |
A61J 1/035 20130101;
A61J 7/0007 20130101; B65D 2575/3218 20130101; B65D 2575/3245
20130101; B65D 75/327 20130101 |
Class at
Publication: |
206/530 |
International
Class: |
B65D 083/04 |
Foreign Application Data
Date |
Code |
Application Number |
Oct 2, 1997 |
JP |
9-269845 |
Claims
1. A press-through pack comprising; an accommodation body (2)
having plural storage recesses (2a) provided with sheet like
portions (2b) therebetween, and a sealing sheet (5) having a
substrate (3) on which one surface side an adhesive layer (4) is
formed, said accomodation body (2) being sealed tightly by said
sealing sheet (5) in a manner that said adhesive layer (4) and said
sheet like portions (2b) are bonded to each other, with a solid
material (T) contained in each of said plural storage recesses (2a)
wherein, said sealing sheet (5) is made of such material that the
part of said sealing sheet (5) responding to said recess (2a), a
part in which a solid material (T) in contained, is partly ruptured
without causing floating and peeling of adhesion portion between
said adhesive layer (4) of said sealing sheet (5) and said sheet
like portion (2b) of said accommodation body (3) when pushing the
projecting portion of the outer side of said recess (2a) with
fingers, whereby said solid material (T) contained in said recess
(2a) is taken out and wherein, said sealing sheet (5) is further
bonded to said sheet like portions (2b) of said accommodation body
(2) in a manner that said sealing sheet (5) is easily peeled off
from said accommodation body (2).
2. The press-through pack as set forth in claim 1, wherein said
solid material (T) is a dividable tablet.
3. The press-through pack as set forth in claim 1 or 2, wherein the
bonding strength between said sealing sheet (5) and said sheet like
portion (2b) of said accommodation body (2) is not less than
0.9N/15 mm width and not more than 3.1N/15 mm width in T peeling
test executed at a peeling speed of 200 mm/min.
4. The press-through pack as set forth in claim 1 or 2, wherein the
bonding strength between said sealing sheet (5) and said sheet like
portion (2b) of said accommodation body (2) is not less than
4.2N/15 mm width and not more than 7.0N/15 mm width in T peeling
test executed at a peeling speed of 100 mm/min.
5. The press-through pack as-set forth in one of claims 1 to 4,
wherein an adhesion lowering component is mixed for an adhesive
component of an adhesive forming said adhesive layer (4).
6. The press-through pack as set forth in one of claims 1 to 5,
wherein said adhesive layer (4) is coated on one surface side of
said sealing sheet (5) by a partial coating method.
7. A sealing sheet (5) for a press-through pack in which a
substrate (3) and an adhesive layer (4) formed on one surface of
said substrate (3) are provided, said adhesive layer (4) being
bonded to sheet like portions (2b) of an accommodation body (2)
having plural storage recesses (2a) provided with sheet like
portions (2b) therebetween, for tightly sealing the accommodation
body (2) wherein, said sealing sheet (5) is made of such material
that the part of said sealing sheet (5) responding to said recess
(2a), a part in which a solid material (T) is contained, is partly
ruptured without causing floating and peeling of adhesion portion
between said adhesive layer (4) of said sealing sheet (5) and said
sheet like portion (2b) of said accommodation body (2) when pushing
the projecting portion of the outer side of said recess (2a) with
fingers, whereby said solid material (T) contained in said recess
(2a) is taken out and wherein, said sealing sheet (5) is designed
to be bonded to said sheet like portions (2b) of said accommodation
body (2) in a manner that said sealing sheet (5) is easily peeled
off from said accommodation body (2).
8. The sealing sheet for the press-through pack as set forth in
claim 7, wherein the bonding strength between said sealing sheet
(5) and said sheet like portion (2b) of said accommodation body (2)
is adjusted not less than 0.9N/15 mm width and not more than
3.1N/15 mm width in T peeling test executed at a peeling speed of
200 mm/min.
9. The sealing sheet for the press-through pack as set forth in
claim 7, wherein the bonding strength between said sealing sheet
(5) and said sheet like portion (2b) of said accommodation body (2)
is adjusted not less than 4.2N/15 mm width and not more than
7.0N/15 mm width in T peeling test executed at a peeling speed of
100 mm/min.
10. A taking-out method of tablets from a press-through pack
wherein, said press-through pack (1) of claim 2 is placed on a flat
plate, all dividable tablets (T) contained in each storage recess
(2a) of said accommodation body (2) of said press-throught pack (1)
are divided by applying an equal force from upward of said
press-through pack (1) placed on the plate by means of a flat
plate, and said sealing sheet (5) is peeled off said accommodation
body (2) and all the divided tablets contained in each storage
recess (2a) of said accommodation body (2) are obtained at one
time.
Description
TECHNICAL FIELD
[0001] The present invention relates to a press-through pack, a
sealing sheet for a press-through pack and a taking-out method of
tablet. Specifically, it relates to a press-through pack wherein a
solid material such as a tablet or the like contained therein can
be taken out easily one by one and also plural solid materials or
all solid materials are taken out at one time if desired, a sealing
sheet appropriate for producing such a press-through pack, and a
taking-out method of tablets wherein all dividable tablets
contained in the press-through pack can be divided at one time and
all of the divided tablets in each storage recess of an
accommodation body can be obtained at one time.
BACKGROUND ART
[0002] A press-through pack (generally called as PTP package) can
contain a solid material one by one in each storage recess (or
pocket) tightly and hygienically sealed and a solid material
contained in the storage recess can be easily obtained one by one.
Therefore, such a press-through pack has been widely used for
individually packing medicines such as a tablet and a capsule, and
confections such as a candy.
[0003] FIG. 7 shows a sectional view of one embodiment of such a
press-through pack. The press-through pack 101 is provided with an
accommodation body 102 and a sealing sheet 105 and is constructed
such that an adhesive layer 104 of the sealing sheet 105 is bonded
to sheet like portions 102b, . . . 102b of the accommodation body
102.
[0004] The accommodation body 102 is made of synthetic resin such
as polyvinyl chloride, polypropylene and cyclic polyolefin and
plural storage recess 102a, . . . 102a generally formed according
to the shape of solid materials T, . . . T to be contained are
connected to the sheet like portions 102b, . . . 102b.
[0005] The sealing sheet 105 has a substrate 103 made of aluminum
foil or the like and an adhesive layer 104 provided on one surface
of the substrate 103.
[0006] According to the press-through pack 101, the adhesive layer
104 of the sealing sheet 105 and the sheet like portions 102b, . .
. 102b of the accommodation body 102 are bonded while containing
the solid materials T, . . . T in the plural storage recesses 102a,
. . . 102a of the accommodation body 102 respectively, and the
accommodation body 102 is tightly sealed by the sealing sheet
105.
[0007] According to such a press-through pack 101, when each
projecting portion 102c, . . . 102c as outer surface of each
storage recess 102a, . . . 102a is pressed, areas R1, . . . R1 of
the sealing sheet 105 tightly sealing each storage recess 102a, . .
. 102a are ruptured by solid materials T, . . . T contained in each
of the storage recesses 102a, . . . 102a, thereby the solid
materials T, . . . T can be obtained out of the press-through pack
101 one by one.
[0008] On the other hand, the dosage amount of medicine is required
to be varied depending on the weight, age and so on of the patient
to be dosed. Therefore, many tablets are provided with a dividing
line along which the tablets are easily divided by fingers or
tools.
[0009] However, the prior press-through pack 101 is designed such
that the solid materials T, . . . T each contained in the recesses
102a, . . . 102a are obtained one by one. Therefore, when medicine
containing plural different components is dividedly packed for one
dosage to a patient at a hospital, a clinic or a pharmacy, a
pharmacist takes the solid materials T, . . . T out of the
press-through pack 101 one by one and the removed solid materials
T, . . . T are dividedly packed for one dosage by means of a
dividedly packing machine. It takes trouble and time for taking the
solid materials T, . . . T out of the press-through pack 101 one by
one. It is requested by a pharmacist and an administrator at a
medical site to provide a press-through pack by which the solid
materials T. T can be obtained one by one and also easily all the
solid materials T, . . . T can be obtained at one time.
[0010] Aluminum foil is widely used as the substrate 103 of the
sealing seat 105 because it is highly dampproof, the solid
materials T can be easily obtained, and it is posh. However, the
aluminum substrate 103 and the accommodation body 102 aren't
separately disposed after all the solid materials T, . . . T are
taken out of the press-through pack 101 so that the treatment of
disposed materials is difficult and they aren't recycled.
DISCLOSURE OF THE INVENTION
[0011] The present invention is proposed to meet the
above-mentioned request.
[0012] Accordingly, an object of the invention is to provide a
press-through pack by which the solid materials stored therein can
easily be obtained one by one, plural solid materials or all of the
solid materials can be obtained at one time and which can be
disposed after separating a sealing sheet and an accommodation
body. And it is also an object of the invention to provide a
sealing sheet which can easily make such a press-through pack.
[0013] Many dividable tablets are obtained from a press-through
pack 101 one by one and each one is manually divided. Such a work
takes a lot of troubles and long time although they have dividing
lines so as to be easily divided by a punch as mentioned above. It
is expected by pharmacists for a long time to propose a taking-out
method of tablets wherein a large amount of tablets are divided at
one time and the divided tablets are easily gathered at one time in
order to improve efficiency of dispensation work.
[0014] A further object of the present invention for satisfying the
pharmacist's request is to provide a taking-out method wherein
dividable tablets contained in a press-through pack are taken out
one by one, also a lot of the dividable tablets are divided at one
time, and the divided tablets are gathered at one time.
[0015] According to the claim 1 of the present invention, a
press-through pack comprised of an accommodation body having plural
storage recesses provided with sheet like portions therebetween,
and a sealing sheet having a substrate on which one surface side an
adhesive layer is formed, said accomodation body being sealed
tightly by said sealing sheet in a manner that said adhesive layer
and said sheet like portions are bonded to each other with a solid
material contained in each of said plural storage recesses wherein,
said sealing sheet is made of such material that the part of said
sealing sheet responding to said recess, a part in which a solid
material is contained, is partly ruptured without causing floating
and peeling of adhesion portion between said adhesive layer of said
sealing sheet and said sheet like portion of said accommodation
body when pushing the projecting portion of the outer side of said
recess with fingers, whereby said solid material contained in said
recess is taken out and said sealing sheet is further bonded to
said sheet like portions of said accommodation body in a manner
that said sealing sheet is easily peeled off from said
accommodation body.
[0016] Here "the sealing sheet is further bonded to the sheet like
portions of the accommodation body in a manner that the sealing
sheet is easily peeled off from the accommodation body" means the
sealing sheet is bonded to the sheet like portion of the
accommodation body so that the sealing sheet is exfoliated from the
sheet like portion of the accommodation body easily and without
being ruptured when a part of the sealing sheet of the
press-through pack is peeled off.
[0017] The material of the accommodation body or the substrate of
the sealing sheet isn't limited if it can be used for a
press-through pack for packing pharmaceuticals, drugs for animals
and plants, confections, health foods, fishing baits, toys and so
on.
[0018] The press-through pack of the claim 2 of the present
invention is characterized in that the solid material is a
dividable tablet.
[0019] More than one dividable tablet may be contained in any of
the storage recesses of the accommodation body of the press-through
pack. The dividable tablet may be contained in the storage recess
in such a manner the surface having a dividing line faces the
accommodation body or the surface opposite to the one having a
dividing line faces the accommodation body. Further, those tablets
may be mixed at random.
[0020] "A dividable tablet" preferably has a dividing line at the
center of the surface thereof and can be divided along the dividing
line when pressure is applied on the surface or the back of the
tablet so that the force is concentrated on the dividing line. More
specifically, it is preferable to use a dividable tablet which has
a dividing line at its center of the surface and at least one of
the surface having a dividing line or its opposite surface may be
formed concave or convex.
[0021] Such a dividable tablet may be a naked tablet (uncoated
tablet) or a coated tablet which is appropriately coated with
coating material on the naked tablet.
[0022] The diameter of a dividable tablet is preferably from 3 mm
to 30 mm and more preferably from 5 mm to 12 mm.
[0023] The tabletting pressure for manufacturing a dividable tablet
is preferably not more than 50N of pressure in the thickness
direction when the tablet is divided and more preferably from 15N
to 40N.
[0024] According to the press-through pack of the claim 3 of the
present invention, the bonding strength of the sealing sheet and
the sheet like portion of the accommodation body in the
press-through pack of the claim 1 or 2 is not less than 0.9N/15 mm
width and not more than 3.1N/15 mm width in T peeling test executed
at a peeling speed of 200 mm/min.
[0025] The unit "N/15 mm width" used in the specification means
peeling strength when T peeling test is executed wherein the
accommodation body and the sealing sheet are bonded, thereafter the
bonded portion thereof is cut into 15 mm width and the cut piece is
used as a test sample.
[0026] The term "T peeling test" means a test according to JIS
(Japanese Industrial Standards) K6845.
[0027] In the above-mentioned range, peeling or floating between
the accommodation body and the sealing sheet isn't caused at the
bonded portion of the sheet like portion of the accommodation body
and the adhesive layer of the sealing sheet other than the storage
recesses (so called a pocket) from where solid materials are taken
by breaking the sealing sheet tightly sealing the storage recesses
by pushing the projecting portions as outer surface of the storage
recesses containing the solid materials into the sheet direction
with fingers, and the sealing sheet is bonded to the sheet like
portion of the accommodation body so as to be easily peeled from
the accommodation body without the sealing sheet ruptured.
[0028] Contrary under the above-mentioned range, the sealing sheet
can be peeled off from the accommodation body without being broken.
However, peeling or floating is caused at the bonded portion of the
sheet like portion of the accommodation body and the adhesive layer
of the sealing sheet other than the storage recesses from where
solid materials are taken by breaking the sealing sheet tightly
sealing the storage recesses by pushing the projecting portions as
outer surface of the storage recesses containing the solid
materials into the sheet direction with fingers.
[0029] Above the above-mentioned range, peeling or floating isn't
caused at the bonded portion of the sheet like portion of the
accommodation body and the adhesive layer of the sealing sheet
other than the storage recesses from where solid materials are
taken by breaking the sealing sheet tightly sealing the storage
recesses by pushing with fingers. However, it is difficult to peel
off or exfoliate the sealing sheet from the accommodation body.
When the sealing sheet is forcedly peeled off, a part of the
sealing sheet is ruptured.
[0030] The bonding strength of the bonded part between the sealing
sheet and the sheet like portion of the accommodation body is
preferably from 1.3N/15 mm width to 2.7N/15 mm width when T peeling
test is carried out at a peeling speed of 200 mm/min.
[0031] According to the press-through pack of the claim 4 of the
present invention, the bonding strength of the sealing sheet and
the sheet like portion of the accommodation body in the
press-through pack of the claim 1 or 2 is not less than 4.2N/15 mm
width and not more than 7.0N/15 mm width in T peeling test executed
at a peeling speed of 100 mm/min.
[0032] In the above-mentioned range, peeling or floating isn't
caused at the bonded portion of the sheet like portion of the
accommodation body and the adhesive layer of the sealing sheet
other than the storage recesses (so called a pocket) from where
solid materials are taken by breaking the sealing sheet tightly
sealing the storage recesses by pushing projecting portions as
outer surface of the storage recesses containing solid materials
into the sheet direction with fingers, and the sealing sheet is
bonded to the sheet like portion of the. accommodation body so as
to be easily exfoliated from the accommodation body without the
sealing sheet ruptured.
[0033] Contrary under the above-mentioned range, the sealing sheet
can be peeled off from the accommodation body without being broken.
However, peeling or floating is caused at the bonded portion of the
sheet like portion of the accommodation body and the adhesive layer
of the sealing sheet other than the storage recesses from where
solid materials are taken by breaking the sealing sheet tightly
sealing the storage recesses by pushing the projecting portions as
outer surface of the storage recesses containing the solid
materials into the sheet direction with fingers.
[0034] Above the above-mentioned range, peeling or floating isn't
caused at the bonded portion of the sheet like portion of the
accommodation body and the adhesive layer of the sealing sheet
other than the storage recesses from where solid materials are
taken by breaking the sealing sheet tightly sealing the storage
recesses by pushing with fingers. However, it is difficult to peel
off or exfoliate the sealing sheet from the accommodation body.
When the sealing sheet is forcedly peeled off, a part of the
sealing sheet is ruptured.
[0035] The bonding strength of the bonded part between the sealing
sheet and the sheet like portion of the accommodation body is
preferably from 4.8N/15 mm width to 6.5N/15 mm width in T peeling
test executed at a peeling speed of 100 mm/min.
[0036] According to the press-through pack of the claim 5 of the
present invention, an adhesion lowering component may be mixed for
an adhesive component of the adhesive forming the adhesive layer of
the sealing sheet of the press-through pack of any of the claims
1-4.
[0037] The "adhesive component" means an adhesive ordinarily used
for heat sealing or cold sealing.
[0038] The "adhesion lowering component" means a component for
weakening the bonding strength of an adhesive component such as an
adhesive with lower bonding strength or a component ordinarily used
for a molding lubricant or a filler. A resin used for a molding
lubricant is for example a silicone resin or fluorocarbon polymer.
When the accommodation body is made of polyvinyl chloride, acrylic
resin can be used as an adhesion lowering component.
[0039] As a filler, pulverized powder such as silicon oxide,
magnesium silicate, titanium oxide, zinc white, calcium carbonate,
almina, and talk can be used.
[0040] According to the press-through pack of the present
invention, the bonding strength is adjusted by mixing an
appropriate amount of bonding strength lowering component in an
adhesive component so that peeling or floating isn't caused at the
bonded portion of the sheet like portion of the accommodation body
and the adhesive layer of the sealing sheet other than the storage
recesses (so called a pocket) from where the solid materials are
taken by breaking a part of the sealing sheet tightly sealing the
storage recesses by pushing the projecting portions as outer
surface of the storage recesses containing the solid materials into
the sheet direction with fingers, and the sealing sheet is bonded
to the sheet like portion of the accommodation body so as to be
easily exfoliated from the accommodation body without the sealing
sheet ruptured.
[0041] According to the press-through pack of the claim 6 of the
present invention, the adhesive layer of the sealing sheet may be
coated on one surface of the sealing sheet of the press-through
pack of any of the claims 1-5 by a partial coating method.
[0042] As the "partial coating method", various methods may be
conceived, and an adhesive may be coated on the surface facing the
accommodation body of the sealing sheet like cross lines or lines
or both cross lines and lines only if the solid materials contained
in the storage recesses can be completely sealed.
[0043] According to such a press-through pack of the present
invention, the bonding strength is adjusted by applying the
adhesive partially so that peeling or floating isn't caused between
the accommodation body and the sealing sheet other than the
so-called pocket from where solid materials are taken by breaking a
part of the sealing sheet tightly sealing the storage recesses by
pushing the projecting portions as outer surface of the storage
recesses containing the solid materials into the sheet direction
with fingers, and the sealing sheet is bonded to the sheet like
portion of the accommodation body so as to be easily peeled from
the accommodation body without the sealing sheet ruptured.
[0044] According to the sealing sheet for a press-through pack of
any one of the claims 7-9 of the present invention, solid materials
contained in a press-through pack can be taken out one by one and
also plural solid materials or all the solid materials are taken
out at one time if desired.
[0045] The sealing sheet for a press-through pack of the claim 7 of
the present invention is provided with a substrate and an adhesive
layer on one surface of the substrate, said adhesive layer being
bonded to a sheet like portion of an accommodation body having
plural storage recesses with sheet like portions therebetween, and
said sealing sheet tightly sealing the accommodation body wherein,
said sealing sheet is made of such material that the part of said
sealing sheet responding to said recess, a part in which a solid
material is contained, is partly ruptured without causing floating
and peeling of adhesion portion between said adhesive layer of the
sealing sheet and said sheet like portion of the accommodation body
when pushing the projecting portion of the outer side of said
recess with fingers, whereby said solid material contained in said
recess is taken out and said sealing sheet is further bonded to
said sheet like portions of said accommodation body in a manner
that said sealing sheet is easily peeled off from said
accommodation body by fingers.
[0046] According to the sealing sheet for the press-through pack
according to the claim 8 of the present invention, the bonding
strength of the sealing sheet for the press-through pack according
to the claim 7 and the sheet like portion of the accommodation body
is not less than 0.9N/15 mm width and not more than 3.1N/15 mm
width in T peeling test executed at a peeling speed of 200
mm/min.
[0047] More preferably, the bonding strength of the sealing sheet
and the sheet like portion of the accommodation body is not less
than 1.3N/15 mm width and not more than 2.7N/15 mm width in T
peeling test executed at a peeling speed of 200 mm/min.
[0048] According to the sealing sheet for the press-through pack
according to the claim 9 of the present invention, the bonding
strength of the sealing sheet for the press-through pack according
to claim 7 and the sheet like portion of the accommodation body is
not less than 4.2N/15 mm width and not more than 7.0N/15 mm width
in T peeling test executed at a peeling speed of 100 mm/min.
[0049] More preferably, the bonding strength of the sealing sheet
and the sheet like portion of the accommodation body is not less
than 4.8N/15 mm width and not more than 6.5 N/15 mm width when T
peeling test is executed at a peeling speed of 100 mm/min.
[0050] The taking-out method of tablets of the claim 10 of the
present invention is characterized in that all dividable tablets
contained in the press-through pack are divided at one time and the
divided tablets are easily obtained at one time. According to such
a method, the press-through pack according to the claim 2 is placed
on a flat plate and all dividable tablets contained in each storage
recess of the accommodation body of the press-through pack are
divided by applying an equal force from upward of the press-through
pack placed on the flat plate by means of a flat plate, and the
sealing sheet is peeled off the accommodation body and all the
divided tablets contained in each storage recess of the
accommodation body are obtained at once.
BRIEF DESCRIPTION OF DRAWINGS
[0051] FIG. 1 is a sectional view of one embodiment of the
press-through pack of the present invention.
[0052] FIG. 2 is schematic diagram showing a dividing test for
dividable tablets.
[0053] FIG. 3 shows one example of a preferable dividable tablet to
be contained in the storage recess of the accommodation body of the
press-through pack of the present invention. FIG. 3(a) is its plane
view, FIG. 3(b) is its back view, and FIG. 3(c) is its side
view.
[0054] FIG. 4 is another example of a preferable dividable tablet
to be contained in the storage recess of the accommodation body of
the press-through pack of the present invention. FIG. 4(a) is its
plane view, FIG. 4(b) is its back view, and FIG. 4(c) is its side
view.
[0055] FIG. 5 is still further example of a preferable dividable
tablet to be contained in the storage recess of the accommodation
body of the press-through pack of the present invention. FIG. 5(a)
is its plane view, FIG. 5(b) is its back view, and FIG. 5(c) is its
side view.
[0056] FIG. 6 is still another example of a preferable dividable
tablet to be contained in the storage recess of the accommodation
body of the press-through pack of the present invention. FIG. 6(a)
is its plane view, FIG. 6(b) is its back view, and FIG. 6(c) is its
side view.
[0057] FIG. 7 is a sectional view showing one example of prior
press-through pack.
BEST MODE FOR CARRYING OUT OF THE INVENTION
[0058] The present invention will be more detailed referring to the
attached drawings.
[0059] FIG. 1 shows a sectional view of one embodiment of the
press-through pack of the present invention. The press-through pack
1 is provided with an accommodation body 2 and a sealing sheet 5
and an adhesive layer 4 of the sealing sheet 5 is bonded to sheet
like portions 2b, . . . 2b of the accommodation body 2.
[0060] The accommodation body 2 is thermoformed according to the
shape of solid materials T, . . . T to be contained and plural
storage recesses 2a, . . . 2a are connected with the sheet like
portions 2b, . . . 2b.
[0061] The material for the accommodation body 2 may be
thermoplastic synthetic resin such as polyvinyl chloride,
polypropylene, polystyrene, cyclic polyolefin and so on. When such
a material is used for the accommodation body 2, the plural storage
recess 2a, . . . 2a can be easily thermoformed according to the
shape of the solid materials T, . . . T to be contained.
[0062] The sealing sheet 5 has a substrate 3 and the adhesive layer
4 provided at one surface of the substrate 3.
[0063] Many kinds of packaging material can be used for the
substrate 3 of the sealing sheet 5 wherein the material can seal
the solid materials T, . . . T to be contained in each storage
recess 2a, . . . 2a of the accommodation body 2 and can be easily
ruptured by the contained solid materials T, . . . T when
projecting portions 2c, . . . 2c as outer surface of the storage
recesses 2a, . . . 2a are pushed into the direction of the sealing
sheet 5. For example, aluminum foil, glassine paper, synthetic
resin sheet containing a filler for easy breakage, a paper, and the
like are exemplified.
[0064] When aluminum foil is used for the substrate 3 of the
sealing sheet 5, its thickness is preferably not less than 5 .mu.m
and not more than 30 .mu.m, and more preferably it is a hard foil
from 15 .mu.m to 25 .mu.m.
[0065] When glassine paper is used for the substrate 3 of the
sealing sheet 5, 30.5 g/m.sup.2 of basis weight (weight per
m.sup.2) is preferable.
[0066] When synthetic resin sheet containing a filler for easy
breakage is used for the substrate 3 of the sealing sheet 5, its
thickness is preferably from 9 .mu.m to 100 .mu.m, and more
preferably from 12 .mu.m to 80 .mu.m.
[0067] Thermoplastic synthetic resin such as polyvinyl chloride,
polypropylene, polystyrene, or striated polyolefin is preferably
used as synthetic resin.
[0068] There are silicon oxide, magnesium silicate, titanium oxide,
zinc white, carcium carbonate, alumina, talc and the like as a
filler contained in the synthetic resin. The average particle
diameter is from 1 .mu.m to 10 .mu.m and the filler may be
contained in the synthetic resin from 5 weight % to 15 weight %,
more preferably from 5 weight % to 70 weight %.
[0069] When paper is used for the substrate 3 of the sealing sheet
5, the basis weight is preferably from 13 g/m.sup.2 to 100
g/m.sup.2.
[0070] The physical property and composition of the substrate 3 of
the sealing material 5 are such that solid materials T can be taken
out by breaking areas R1, . . . R1 sealing the storage recesses 2a,
. . . 2a of the sealing sheet 5 which seal the storage recess, when
the projecting portions 2c as outer surface of the storage recesses
2a containing the solid materials T are pushed by fingers.
[0071] Although the above-mentioned construction is the same as the
prior press-through pack 101, according to the press-through pack 1
of the present invention, the bonding strength of the adhesive
layer 4 of the sealing sheet 5 and the sheet like portions 2b, . .
. 2b of the accommodation body 2 is adjusted such that breakage of
the sealing sheet 5 doesn't spread to adhesive parts R2, . . . R2
of the sheet like portion 2b and the adhesive layer 4, and only the
areas R1, . . . R1 of the sealing sheet 5 ( so called a pocket )
sealing the storage recesses 2a, . . . 2a are ruptured so that the
solid materials T, . . . T can be taken out one by one when each
projecting portion 2c, . . . 2c as outer surface of the storage
recesses 2a, . . . 2a containing the solid materials T, . . . T is
pushed in the direction of the sealing sheet 5 by fingers. It is
also adjusted such that the sealing seat 5 can be easily separated
from the accommodation body 2 without being ruptured halfway.
[0072] Then adjustment method of bonding strength of the sealing
sheet 5 will be explained for the cases when the bonding strength
of the adhesive layer 4 is adjusted by the component of the
adhesive and when the bonding strength of the adhesive is adjusted
by a coating method for the substrate 3 of the sealing sheet 5.
[0073] A. Case that Bonding Strength is Adjusted by the Component
of Adhesive
[0074] In this case appropriate amount of adhesion lowering
component is included in the adhesive component.
[0075] Any material can be used for the adhesive component if it
can bond the accommodation body 2 and the substrate 3 of the
sealing sheet 5, and for example, thermoplastic resin capable of
heat sealing or cold sealing adhesive capable of cold sealing may
be used.
[0076] Vinyl chloride vinyl acetate copolymer can be preferably
used as thermoplastic resin capable of heat sealing when the
accommodation body 2 is made of polyvinyl chloride, chlorinated
polypropylene or carboxyl polypropylene is preferably used for the
accommodation body 2 made of polypropylene, and the mixture of
vinyl chloride/vinyl acetate copolymer and acrylic acid resin is
preferably used for the accommodation body 2 made of polystyrene,
however, the present invention isn't limited to such a
material.
[0077] Acrylic acid resin, silicon resin, rubber or the like may be
used as a cold sealing adhesive.
[0078] The "cold sealing adhesive" indicates an adhesive which can
bond members only by pressurizing.
[0079] As the adhesion lowering component included in the adhesive,
any material which can lower the bonding strength of the adhesive
layer 4 of the sealing sheet 5 and the accommodation body 2 or the
bonding strength of the adhesive layer 4 of the sealing sheet and
the substrate 3 of the sealing sheet 5 may be used.
[0080] For example, resin used as molding lubricant such as silicon
resin or fluorine-contained resin, acrylic acid resin, or striated
polyester resin is preferable.
[0081] Pulverized powder used as a filler such as silicon oxide,
magnesium silicate, titanium oxide, zinc white, calcium carbonate,
alumina, or talc is also preferable.
[0082] The composition ratio of the adhesive component of the
adhesive and the adhesion lowering component is determined
according to the result of an bonding strength test, an extrusion
test and a peeling test which will be explained later.
[0083] B. Case that Bonding Strength is Adjusted by a Coating
Method of Adhesive on the Substrate of the Sealing Sheet
[0084] In this case, a desirable bonding strength can be obtained
by coating an adhesive on the substrate 3 of the sealing sheet 5
entirely or partially or by adjusting the coating amount of an
adhesive per unit area on the substrate 3 of the sealing sheet
5.
[0085] When the adhesive is partially coated, it may be coated like
a mesh or lines on the surface facing to the accommodation body 2
of the sealing sheet 5 only if the solid materials T, . . . T can
be completely sealed in each storage recess 2a of the accommodation
body 2 respectively, or such a coating method may be combined.
[0086] When the coating amount per unit area on the substrate 3 of
the sealing sheet 5 is adjusted, a thinner may be mixed in the
adhesive or the layer thickness per unit area of the adhesive
coated on the substrate 3 of the sealing sheet 5 may be
adjusted.
[0087] When the bonding strength is adjusted by a coating method of
the adhesive on the substrate 3 of the sealing sheet 5, adhesive
lowering component may be contained or not contained in the
adhesive.
[0088] Next, the present invention will be explained exemplifying
concrete experimental results.
[0089] (Experiment 1)
[0090] (Manufacturing of a Sealing Sheet and a Sample for a Bonding
Strength Test of a Sealing Sheet and a Sheet like Portion of an
Accommodation Body)
[0091] Heat sealing agent for polyvinyl chloride (Leader Co., Ltd.,
brand name: LD830G) of which main ingredient was copolymer of vinyl
chloride and vinyl acetate was used as an adhesive component.
Acrylic resin (Konishi Co., Ltd., brand name: KV610) which was an
adhesive lowering component was mixed and plural samples of an
adhesive agent solution of which heat sealing strength (bonding
strength) was adjusted by varying its component ratio were
prepared. The samples were coated on the surface of an aluminum
foil (hard foil) (the substrate 3 of the sealing sheet 5) with 20
.mu.m thickness by means of a bar coater #12.
[0092] Then the aluminium foils (the substrate 3 of the sealing
sheet 5) were dried by a heat dryer at 200.degree. C. for 20
seconds and plural sealing sheets 5 having adhesive layers 4 with
several bonding strengths were manufactured.
[0093] Such manufactured sealing sheets 5 were thermally sealed
with polyvinyl chloride sheet (Sumitomo Bakelite Co., Ltd., brand
name: VSS1202) as the accommodation body 2 by means of a heat
sealer (Yasuda Seiki Co., Ltd., lever type heat sealer) having a
flat plate as a heat seal bar at 150.degree. C..times.3 Kg
pressure/c m.sup.2.times.1 second.
[0094] (Bonding Strength Test of a Sealing Sheet and a Sheet like
Portion of an Accommodation Body)
[0095] The above-mentioned thermoformed sheets were cut into 15 mm
width and the cut pieces were used as samples for measuring bonding
strength.
[0096] Bonding strength test was executed by measuring peeling
strength by means of Instoron type tensile strength measuring
device (Shimadzu Corporation, type : AGS-100-D).
[0097] T peeling test was executed at 200 mm/min. peeling speed
according to JIS K6845.
[0098] (Manufacturing of an Evaluation Sample for an Extrusion Test
and a Peeling Test)
[0099] Plural press-through packs 1 were manufactured by heat
sealing each sealing sheet 5 having the above-mentioned adhesive
layer 4 on the aluminum foil (the substrate 3 of the sealing sheet
5) and the accommodation body 2 by means of a PTP filling machine
(CKD Corporation, type : M-1).
[0100] Polyvinyl chloride sheet (Sumitomo Bakelite Co., Ltd., brand
name: VSS1202) was used for the accommodation body 2, No. 4 capsule
as a solid substrate T was contained in each storage recess 2a made
by thermoforming, and the accommodation body 2 was heat sealed at
190.degree. C., thereby evaluation samples were manufactured for an
extrusion test and a peeling test. The sheet without storage
recesses 2a was cut into 15 mm width for which a bonding strength
test of the sealing sheet and the sheet like portion of the
accommodation body was executed.
[0101] (Extrusion Test)
[0102] For each press-through pack 1 manufactured as mentioned
above, the No. 4 capsule contained in each storage recess 2a was
obtained by breaking the sealing sheet 5 by pushing (by fingers)
the contained capsule from the projecting portion 2c (polyvinyl
chloride sheet side) as outer surface of the storage recess of the
accommodation body 2 into the direction of the sealing sheet 5.
Peeling and floating were observed for the adhesion areas R2 of the
adhesive layer 4 of the sealing sheet 5 and the sheet like portions
2b, . . . 2b of the accommodation body 2 except for the areas R1
sealing the storage recess 2a from which the No. 4 capsules were
obtained.
[0103] When peeling and floating of the sealing sheet 5 weren't
observed at the areas R2, it was evaluated as good (.largecircle.).
When peeling and floating were partially observed at the areas R2
other than the areas R1 corresponding to storage recesses 2a from
which the No. 4 capsules were obtained, it was evaluated as not so
good (.DELTA.). When peeling and floating were widely observed at
the areas R2 other than the areas R1 corresponding to storage
recesses 2a from which the No. 4 capsules were obtained, it was
evaluated as not good (X).
[0104] (Peeling Test)
[0105] The same samples of the press-through pack 1 as the samples
used for the extrusion test were used and rupture of the sealing
sheet 5 was observed when the sealing sheet 5 was peeled off the
accommodation body 2 (polyvinyl chloride sheet).
[0106] When the sealing sheet 5 was easily peeled off the
accommodation body 2 (polyvinyl chloride sheet) without being
ruptured or cut, it was evaluated as good (.largecircle.). When the
sealing sheet 5 was easily peeled off the accommodation body 2
(polyvinyl chloride sheet) however the sealing sheet 5 was cut or
ruptured, it was evaluated as not so good (.DELTA.). When the
sealing sheet 5 was difficult to be peeled off the accommodation
body 2 (polyvinyl chloride sheet) and was cut or ruptured when it
was forcibly peeled off the accommodation body 2 (polyvinyl
chloride sheet), it was evaluated as not good (X).
[0107] The result is shown in the following table 1.
1 TABLE 1 Component quantity main ingredient 4 mg Lactose
appropriate amount Starch 40 mg polyvinyl alcohol 4 mg magnesium
stearate 1 mg total weight 130 mg
[0108] According to the table 1, it was understood that the
preferable bonding strength of the accommodation body 2 and the
sealing sheet 5 was from 0.9N/15 mm width to 3.1N/15 mm width.
[0109] Further, it became apparent that the bonding strength of the
sealing sheet 5 and the sheet like portion 2b of the accommodation
body 2 was preferably adjusted from 1.3N/15 mm width to 2.7N/15 mm
width by repeating similar tests.
[0110] The compensated value in the table 1 indicates a value on
the regression line obtained by analyzing the actual measurement
and is a value compensated by the following equation.
N=-0.0871X+9.1695(N: compensated value)
R.sup.2=0.9965(R: confidence limit)X=weight % of KV610
[0111] (Experiment 2)
[0112] (Manufacturing of a Sealing Sheet and a Press-Through
Pack)
[0113] Heat sealing agent for polyvinyl chloride (Leader Co., Ltd.
Brand name: LD830G) of which main ingredient was copolymer of vinyl
chloride and vinyl acetate was used as an adhesive component.
Acrylic resin (Konishi Co., Ltd., brand name: KV610) which was an
adhesive lowering component was mixed and plural samples of an
adhesive agent solution of which heat sealing strength (bonding
strength) was adjusted by varying its component ratio were
prepared. The samples were coated on the surface of an aluminum
foil (hard foil) with 20 .mu.m thickness (the substrate 3 of the
sealing sheet 5) by means of a bar coater #12.
[0114] Then the foils (the substrate 3 of the sealing sheet) were
dried by a heat dryer at 200.degree. C. for 20 seconds and plural
sealing sheets 5 having adhesive layers 4 with several bonding
strengths were manufactured.
[0115] Plural storage recesses 2a are thermally formed in lines for
containing tablets having concave plain and 7 mm diameter
(hereinafter called 7 mm diameter tablet) by a junior blister
packing machine from polyvinyl chloride sheet (Sumitomo Bakelite
Co., Ltd., brand name: VSS1105SF). The 7 mm diameter tablet was
contained in each storage recess 2a formed as mentioned above. The
accommodation body 2 and plural sealing sheets 5 having adhesive
layers 4 of several bonding strength on the substrates 3 were
thermally bonded at 130.degree. C. by means of semi-automatic PTP
packing machine (Daiwa Kasei Kogyo Co., Ltd, Type:K-200KS), thereby
plural press-through packs 1 containing 7 mm diameter tablets were
manufactured.
[0116] (Extrusion Test)
[0117] For each press-through pack 1 manufactured as mentioned
above, the 7 mm diameter tablet contained in each storage recess 2a
was obtained by breaking the sealing sheet 5 by pushing (by
fingers) the contained tablet from the projecting portion 2c
(polyvinyl chloride sheet side) as outer surface of the storage
recess of the accommodation body 2 into the direction of the
sealing sheet 5. Peeling and floating were observed for the
adhesion areas R2 of the adhesive layer 4 of the sealing sheet 5
and the sheet like portions 2b, . . . 2b of the accommodation body
2 except for the areas R1 sealing the storage recesses 2a from
which the 7 mm diameter tablets were obtained.
[0118] When peeling and floating of the sealing sheet 5 (aluminum
foil) weren't observed at the areas R2, it was evaluated as good
(.largecircle.). When peeling and floating were partially observed
at the areas R2 other than the areas R1 corresponding to storage
recesses 2a from which the 7 mm diameter tablets were obtained, it
was evaluated as not so good (.DELTA.). When peeling and floating
the sealing sheet were widely observed at the areas R2 other than
the areas R1 corresponding to storage recesses 2a from which the 7
mm diameter tablets were obtained, it was evaluated as not good
(X).
[0119] (Peeling Test)
[0120] The same samples of the press-through pack 1 as the samples
used for an extrusion test were used and rupture of the sealing
sheet 5 was observed when the sealing sheet 5 was peeled off the
accommodation body 2 (polyvinyl chloride sheet).
[0121] When the sealing sheet 5 was easily peeled off the
accommodation body 2 (polyvinyl chloride sheet) without being
ruptured or cut, it was evaluated as good (.largecircle.). When the
sealing sheet 5 was easily peeled off the accommodation body 2
(polyvinyl chloride sheet) however it was cut or ruptured, it was
evaluated as not so good (.DELTA.). When the sealing sheet 5 was
difficult to be peeled off the accommodation body 2 (polyvinyl
chloride sheet) and was cut or ruptured when it was forcibly peeled
off the accommodation body 2 (polyvinyl chloride sheet), it was
evaluated as not good (X).
[0122] (Bonding Strength Test of a Sealing Sheet and a Sheet like
Portion of an Accommodation Body)
[0123] The bonding part R2 (where the storage recesses 2a of the
accommodation body 2 aren't provided) of the sheet like portions 2b
of the accommodation body 2 and the sealing sheet 5 of each
press-through pack 1 manufactured as mentioned above was cut into
15 mm width and the cut pieces were used as samples for measuring
bonding strength.
[0124] The bonding strength test was executed by measuring peeling
strength by means of a strograph (TOYO SEIKI Co., Ltd., type
M1).
[0125] T peeling test was executed according to JIS K6845 at a
peeling speed of 100 mm/min.
[0126] The result is shown in the following table 2.
2 TABLE 2 bonding strength (N/15 mm width) (peeling speed:
extrusion 100 mm/min.) (7 mm Component ratio actual compensated
diameter peel- of adhesive measurement value tablet) ing
LD830G/KV610 = 50/50 9.6 9.3 .smallcircle. x LD830G/KV610 = 40/60
8.8 8.1 .smallcircle. x LD830G/KV610 = 35/65 7.4 7.6 .smallcircle.
x LD830G/KV610 = 30/70 6.1 7.0 .smallcircle. .DELTA. LD830G/KV610 =
25/75 5.8 6.5 .smallcircle. .smallcircle. LD830G/KV610 = 20/80 5.7
5.9 .smallcircle. .smallcircle. LD830G/KV610 = 10/90 5.1 4.8
.smallcircle. .smallcircle. LD830G/KV610 = 5/95 4.7 4.2 .DELTA.
.smallcircle. LD830G/KV610 = 3/97 4.1 4.0 x .smallcircle.
[0127] From the table 2, it was understood that the preferable
bonding strength of the accommodation body 2 and the sealing sheet
5 was from 4.2N/15 mm width to 7.0N/15 mm width.
[0128] Further, it became apparent that the bonding strength of the
sealing sheet 5 and the sheet like portion 2b of the accommodation
body 2 was preferably adjusted from 4.8N/15 mm width to 6.5N/15 mm
width by repeating similar tests.
[0129] The compensated value in the table 2 indicates a value on
the regression line obtained by analyzing the actual measurement
and is a value compensated by the following equation.
N=-0.1123X+14.882(N: compensated value)
R.sup.2=0.8968(R: confidence limit)X=weight % of KV610
[0130] When aluminum foil is used for the substrate 3 of the
sealing sheet 5, a print layer may be provided for showing company
name, brand name, brand code and so on at the surface provided with
the adhesive layer 4 or its opposite surface. Further, a surface
protection layer made of nitrocellulose, acrylic resin, epoxy
resin, melamine resin or a mixed resin of at least two of them may
be provided on the printing surface opposite to the surface with
the adhesive layer 4 in order to prevent spots such as fingerprint
and erosion, or to polish.
[0131] If necessary, V-shaped grooves or perforations may be
provided for the sheet like portions 2b, . . . 2b of the
accommodation body 2 for separating per each storage recess 2a, . .
. 2a.
[0132] (Dividing Test of Dividable Tablet)
[0133] Granule including lactose--starch as additives was tabletted
at various tabletting pressures and several kinds of dividable
tablets having a dividable line, with 7 mm diameter and 130 mg
total weight were manufactured.
3 TABLE 3 bonding strength (N/15 mm width) (peeling speed: 200
mm/min.) extrusion component ratio actual compensated (No. 4 peel-
of adhesive measurement Value capsule) ing LD830G/KV610 = 50/50 4.9
4.8 .smallcircle. x LD830G/KV610 = 40/60 3.9 3.9 .smallcircle. x
LD830G/KV610 = 35/65 3.4 3.5 .smallcircle. x LD830G/KV610 = 30/70
3.0 3.1 .smallcircle. .DELTA. LD830G/KV610 = 25/75 2.7 2.6
.smallcircle. .smallcircle. LD830G/KV610 = 20/80 2.1 2.2
.smallcircle. .smallcircle. LD830G/KV610 = 10/90 1.3 1.3
.smallcircle. .smallcircle. LD830G/KV610 = 5/95 1.0 0.9 .DELTA.
.smallcircle. LD830G/KV610 = 3/97 0.8 0.7 x .smallcircle.
[0134] Then the press-through pack 1A as mentioned above was
similarly manufactured but thus prepared several kinds of tablets
were used instead of the No. 4 capsule or the 7 mm diameter
tablet.
[0135] The press-through pack 1A containing dividable tablets Td, .
. . Td with a dividing line L in the storage recesses 2a, . . . 2a
of the accommodation body 2 was placed on the flat plate 21S on a
table 21 as shown in FIG. 2(a). A plastic plate 22 of about the
same size as the press-through pack 1A was pressed above the
press-through pack 1A so that the accommodation body 2 of the
press-through pack 1A was pushed into the direction of the sealing
sheet 5 (see FIG. 2(b)). Then the dividable tablets Td, . . . Td
contained in the storage recesses 2a, . . . 2a of the accommodation
body 2 were divided. The divided condition thereof were observed
(see FIG. 2(c)).
[0136] As the result, the dividable tablets Td, . . . Td of the
shapes shown in FIG. 3-FIG. 6 contained in each storage recess 2a,
. . . 2a, and divided at a pressure in the direction of the
thickness of tablet of not more than 50N, more specifically from
15N to 40N were all divided into two in each storage recess 2a, . .
. 2a.
[0137] The shapes of the dividable tablets will be explained in
more detail. The dividable tablet Td1 in FIG. 3 has a V-shaped
dividing line L at a center of one surface Sa thereof. The surface
Sa of the tablet Td1 provided with the dividing line L is formed
concave so that the deepest portion accords with the position of
the dividing line L and a corner D1 of the concave surface and a
side Sc of the tablet is rounded. Further, a surface Sb opposite to
the surface Sa of the tablet Td1 having the dividing line L is
formed convex of which highest portion accords with the most
deepest portion of the dividing line L.
[0138] When pressure is applied on the dividable tablet Td1,
ripping force is concentrated on the dividing line L by cooperation
of the concave surface Sa and the convex surface Sb so that the
dividable tablet Td1 can be easily divided along the dividable line
L.
[0139] The dividable tablet Td2 in FIG. 4 is provided with an
annular part C with a fixed space from its circumference for a
design purpose on the surface Sb opposite to the surface Sa having
a dividing line L and also provided with a convex surface inside of
the annular part C. Its construction is actually similar to the
construction of the dividable tablet Td1 and their effects are the
same.
[0140] The dividable tablet Td3 in FIG. 5 is provided with a
V-shaped dividing line L of which deepest portion is deeper than a
corner D2 of a surface Sa and a side Sc of the tablet Td3. The
surface Sa with the dividing line L is flat, the corner D2 is
rounded, and convex surface is formed at a surface Sb opposite to
the surface Sa.
[0141] When pressure is applied on the dividable tablet Td3,
ripping force is concentrated on the dividing line L because of the
convex shape of the surface Sb and the dividing line L is formed
V-shaped, thereby the tablet Td3 can be easily divided along the
dividing line L.
[0142] The dividable tablet Td4 shown in FIG. 6 has a V-shaped
dividing line L at a center of one surface Sa thereof and the
surface Sa is designed such that V-shaped form which is gentle
comparing to the dividing line L is continued from the dividing
line L to the side Sc of the tablet Td4 so that the deepest part
thereof accords with the position of the dividing line L. A corner
D3 of the V-shaped surface and the side Sc is rounded and a surface
Sb opposite to the surface Sa is gently V-shaped having the deepest
portion thereof at the center. The deepest portion of the V-shaped
surface Sb is designed to be aligned with the dividing line L of
the surface Sa and a corner D4 of the gently V-shaped surface Sb
and the side Sc of the tablet is rounded.
[0143] When pressure is applied on the dividable tablet Td4, the
tablet Td4 can be easily divided because pressure applied on the
gently V-shaped surface Sa is concentrated on the dividing line L
and the deepest part of the V-shaped surface Sb accords with the
deepest part of the V-shaped dividing line L.
[0144] As shown in FIG. 2(d), the sealing sheet 5 was peeled off
the accommodation body 2 of the press-through pack 1A containing
divided tablets Tdh, . . . Tdh in the storage recesses 2a, . . .
2a, the sheet 5 could be peeled off without being ruptured and all
the divided tablet Tdh, . . . Tdh could be obtained.
[0145] When the dividable tablets Td, . . . Td contained in the
storage recesses 2a, . . . 2a were pushed into the sealing sheet 5
direction from the accommodation body 2 (polyvinyl chloride sheet)
and taken out one by one by breaking the sealing sheet 5, it was
observed whether peeling or floating was occurred at the areas R2
other than the areas R1 of the accommodation body 2 from where the
dividable tablets Td were taken out. The press-through pack 1A
containing dividable tablets Td1, Td2, Td3, Td4 in each storage
recess 2a, . . . 2a didn't cause peeling or floating at the areas
R2 and the dividable tablets Td1, Td2, Td3, Td4 were taken out of
the press-through pack 1A without divided respectively.
[0146] Each press-through pack 1A containing the dividable tablets
Td1, Td2, Td3, Td4 was packed in a box (10 tablets PTP.times.100
sheets) and transported by a regular delivery method. In such a
test, any of the dividable tablets Td1, Td2, Td3, Td4 contained in
each storage recess 2a, . . . 2a of the press-through pack 1A
weren't divided or dropped outside by breaking the sealing sheet
5.
[0147] At least one dividable tablet Td may be contained in each
storage recess 2a, . . . 2a of the accommodation body 2 of the
press-through pack 1A. The dividable tablet Td may be positioned in
the recess 2a while the surface Sa with a dividing line L faces the
accommodation body 2 or the surface Sb faces the accommodation body
2. Further, the surfaces Sa of some tablets Td may face the
accommodation body 2 and the surfaces Sb of the others face the
accommodation body 2.
[0148] The tablets Td1, Td2, Td3, Td4 are only a sample of
dividable tablets contained in the storage recess 2a, . . . 2a of
the accommodation body 2. Any types of dividable tablets may be
used only if the tablets Td can be divided along the dividing line
L when pressure is applied on the surface Sa having the dividing
line L or on the surface Sb opposite to the surface Sa and the
force is concentrated on the line L.
[0149] It is preferable that a concave or a convex is formed on at
least one surface Sa having a dividing line L of the tablet Td or
its opposite surface Sb so that the tablets can be easily divided
along the dividing line L.
[0150] Such a dividable tablet may be a naked tablet (uncoated
tablet) or a coated tablet wherein coating material such as
sugarcoating or film coating is appropriately applied on the naked
tablet.
[0151] The diameter of a dividable tablet is preferably from 3 mm
to 30 mm and more preferably from 5 mm to 12 mm considering
practical prescription such as patient compliance.
[0152] Industrial Applicability
[0153] According to the press-through pack of the present
invention, solid materials can be obtained one by one by breaking
the part of the sheet sealing the storage recess without causing
floating or peeling at the adhesion area of the sheet like portion
of the accommodation body and the adhesive layer of the sealing
sheet when the projecting portions as outer surface of the storage
recess containing solid materials are pushed in the direction of
the sealing sheet by fingers. Further, when the sealing sheet was
peeled off the accommodation body, plural or whole solid materials
contained in the press-through pack can easily be obtained at one
time because the sealing sheet is bonded to the accommodation body
so as to be easily peeled off without being broken.
[0154] The accommodation body and the sealing sheet can be easily
separated after all the solid materials are obtained so that
disposal treatment and recycle are easily accomplished by disposing
them separately.
[0155] Further according to the present invention, when dividable
tablets are contained in the storage recesses, they can be obtained
one by one and also a large amount of tablets can be divided at one
time and the divided tablets can be easily obtained at one
time.
[0156] When the press-through pack of the present invention is
used, solid materials can be obtained by pushing the projecting
portions as outer surface of the storage recesses containing solid
materials and breaking the part of the sheet sealing the storage
recesses. And also when the sealing sheet is peeled off, it can be
easily separated from the accommodation body without being
broken.
[0157] The press-through pack of the present invention has such an
excellent effect so that it can be preferably used for individually
packing materials such as solid medicine like a tablet or a
capsule, confections like a candy, and solid materials like health
food, fishing baits or toys.
[0158] The sealing sheet for the press-through pack of the present
invention is preferably used for manufacturing individual packing
form of such solid materials.
[0159] Further according to the taking-out method of the present
invention, a dividable tablet can be obtained from the
press-through pack one by one and also a large amount of dividable
tablet can be divided in the press-through pack and obtained at one
time.
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