U.S. patent application number 10/362808 was filed with the patent office on 2004-02-12 for carded blister pack.
Invention is credited to Hughes, David.
Application Number | 20040026293 10/362808 |
Document ID | / |
Family ID | 9898436 |
Filed Date | 2004-02-12 |
United States Patent
Application |
20040026293 |
Kind Code |
A1 |
Hughes, David |
February 12, 2004 |
Carded blister pack
Abstract
A blister pack (20) folded wallet has a mounting card (12), with
a [hinged] spine segment (15), and an adhesive edge strip (16).
Overlaid by a pre-formed blister pack (11), for mutual (edge)
entrainment; a dedicated assembly machine entrains mounting cards
and blister packs stored in respective magazines. Child resistance
is available through cover latching and/or paper reinforced foil
laminate (161), with through apertures (166) and perforations (163,
165) for selective localised paper patch (169) removal, over
individual blister pockets (168).
Inventors: |
Hughes, David; (Flintshire,
GB) |
Correspondence
Address: |
LAW OFFICES OF
DONALD N. MACINTOSH
180 MONTGOMERY, STE. 600
SAN FRANCISCO
CA
94104
US
|
Family ID: |
9898436 |
Appl. No.: |
10/362808 |
Filed: |
August 4, 2003 |
PCT Filed: |
July 31, 2001 |
PCT NO: |
PCT/GB01/03425 |
Current U.S.
Class: |
206/538 ;
206/531; 206/534.1 |
Current CPC
Class: |
B65B 15/00 20130101;
B65D 75/327 20130101; A61J 1/035 20130101; B65D 75/38 20130101;
B65D 2203/00 20130101 |
Class at
Publication: |
206/538 ;
206/531; 206/534.1 |
International
Class: |
B65D 083/04 |
Claims
1. A carded blister pack, comprising a mutually entrained blister
pack, of multiple blister pockets, and mounting card; with a common
edge bonding joint, defining a fold spine, about which the card can
fold, to overlie the blister pack, as a hinged cover; a foil
rupture layer over the blister pockets; a paper backing surmounting
the foil; prise 'n-peel access to blister pocket margins, for local
removal of paper backing, to a foil rupture layer, over individual
pockets.
2. {adhesive edge strip} A carded blister pack, as claimed in claim
1, bonded by an adhesive edge strip, upon either one, or both, card
and blister.
3. {adhesive bonding} A carded blister pack, as claimed in claim 1,
bonded with adhesive, selected from the group comprising (a) and/or
(b) and/or (c), where (a) (airless) contact, (b) twin chemically
interactive component curing, (c) hot melt.
4. {hinged spine} A carded blister pack, as claimed in claim 1,
comprising a mounting card, with a hinged spine, and an adhesive
portion, overlaid by a pre-formed blister pack, configured to allow
a card leaf or panel to fold over, upon the blister pack, as a
[hinged] protective cover.
5. {spine crease} A carded blister pack, as claimed in claim 1,
including a crease or fold line, between spine (segment) and
adhesive portion, to facilitate card over-turn about the spine, to
overlie the blister pack.
6. {localised weakening} A carded blister pack, as claimed in claim
1, including, in the card body, a localised weakening, perforation
or severance line, adjacent the spine, to facilitate mutual
severance and separation, of card and blister.
7. {book jacket} A carded blister pack, as claimed in claim 1, with
a mounting card configured as a jacket, having mutually hinged
panels or leafs, disposed about an intervening spine, at opposite
sides of the blister pack.
8. {multiple spines} A carded blister pack, as claimed in claim 1,
incorporating multiple spines, or spine segments.
9. {concertina folded spines} A carded blister pack, as claimed in
claim 1, incorporating a concertina-folded, multiple spine, or
segmented spine.
10. {staggered spines} A carded blister pack, as claimed in claim
1, with staggered, or mutually-offset, multiple spine, or spine
segment, folds.
11. {multiple blisters upon common spine} A carded blister pack, as
claimed in claim 1, with multiple blister packs, as leaves upon a
common spine.
12. {differential blisters upon common spine} A carded blister
pack, as claimed in claim 1, with differential blister packs, as
leaves upon a common single spine, or multiple spines.
13. {paper backed foil} A carded blister pack, as claimed in claim
1, including a paper backed foil, blister backing layer.
14. {perforated paper backing} A carded blister pack, as claimed in
claim 1, including a paper-backed foil blister backing layer, with
perforations, aligned with the margins of blisters, to facilitate
identification, and local separation from the foil, of a paper
backing layer portion, over a designated blister pocket.
15. {cover portions} A carded blister pack, as claimed in claim 1,
with cover portions along opposite edges, and a mechanical
interlock or latch, such as a slot and inter-fitting profiled tab,
operative therebetween, once cover portions are folded to overlie
the blister; a local, tear-of, tab upon one cover portion, allowing
mutual release of cover portions.
16. {tear-off severance tab} A carded blister pack, as claimed in
claim 1, with mutual entrainment of card and blister, along
opposite edges, with a tear-off severance tab, allowing release of
one edge, creating a hinged cover, about the edge still
entrained.
17. {tear-off edge tab & residual cover} A carded blister pack,
as claimed in claim 1, with mutual entrainment of card and blister,
along four successive side edges, featuring a tear-off release tab,
juxtaposed with one edge, to allow part-separation of a card edge,
and creation of a residual hinged cover, upon end closure flaps,
about residual opposite edges.
18. {carded blister pack assembly machine} A machine for assembly
of carded blister packs, as claimed in claim 1, with a mounting
card storage magazine, and a blister pack storage magazine, a
conveyor for transferring mounting cards, discharged individually
in succession from the mounting card storage magazine, through an
intervening adhesive application station, into juxtaposition with
individual blister packs, discharged individually in succession,
from the blister pack storage magazine.
19. {free paper edge} A carded blister pack, comprising a mutually
entrained blister pack, of multiple blister pockets, and a mounting
card; with a common edge bonding joint, defining a fold spine,
about which the card can fold, to overlie the blister pack, as a
hinged cover; a toil rupture layer, disposed over the blister pack;
a paper backing, surmounting the foil over blister pockets, to
inhibit foil rupture; locally free paper backing edge, at or
adjacent blister pocket margins, for local prise 'n-peel removal of
paper backing, to expose an underlying foil rupture layer, over
individual pockets, allowing foil rupture and access to pocket
contents.
20. {exposed detached paper edge} A carded blister pack, comprising
a mutually entrained blister pack of multiple blister pockets, and
a mounting card; with a common edge bonding joint, defining a fold
spine, about which the card can fold, to overlie the blister pack,
as a hinged cover; a foil rupture layer over the blister pack, a
paper backing attached to the foil upon blister pockets, an array
of perforations and/or cuts, through the paper overlay, separating
and bounding individual blister pockets; an accessible edge to a
region of paper (locally) detached from the foil underlay, for
local prise 'n-peel removal of paper backing, to a foil rupture
layer, over individual pockets, and access to pocket contents, by
local foil rupture.
21. {exposed paper edge & slit} A carded blister pack,
comprising a mutually entrained blister pack of multiple blister
pockets, and a mounting card; with a common edge bonding joint,
defining a fold spine, about which the card can fold, to overlie
the blister pack, as a hinged cover; a foil rupture layer over the
blister pack, a paper backing overlying and attached to the foil
upon blister pockets; perforations and/or cuts through the paper
overlay, to differentiate and bound individual blister pockets; a
region of local detachment of paper from foil underlay, a slit in
the detached paper, to create a free paper access edge, at a
selected blister pocket margin, in turn to allow edge prise 'n-peel
removal of local paper overlay, and underlying foil rupture, for
access to contents of a selected pocket.
Description
[0001] This invention relates to so-called `blister packs` (or
simply `blisters`) and is particularly, but not exclusively,
concerned with blister pack mounting, capture or entrainment in,
with, upon, or in relation to other elements or structures--say for
ease and security of transport and/or storage.
[0002] Some aspects of the invention are concerned with
tamper-resistant, in particular child-resistant, and/or tamper
evident (blister) pack features.
[0003] Terminology
[0004] The term `blister pack` is used herein to embrace a
pre-formed or pre-configured packaging sheet or layer, for example
configured as a shallow tray, pre-profiled with multiple localised
compartments or pockets.
[0005] The individual compartment profile conveniently complements
that of the intended contents, to ensure a snug relative
interfit.
[0006] The pocket wall affords some resistance to impact, but is
typically deformable to allow contents displacement and ejection,
and modest cushioning action.
[0007] The term `child-resistant` signals certain measures to
impede `unauthorised` pack opening or access to children, as
particularly vulnerable, `innocent`, irresponsible or uneducated
consumers--such as might otherwise arise by casual or curious
handling, as encountered in child play.
[0008] Such provision represents a precautionary or deterrent
measure, rather than necessarily an absolute defence.
BACKGROUND
[0009] Blister pack pre-formation is commonly by moulding a thin
sheet synthetic plastics or laminate material into a multi-pocket
or compartment tray.
[0010] This may be undertaken continually on-line followed by pack
fill and closure.
[0011] Pockets are commonly disposed in a rectangular grid
array.
[0012] An individual pocket is generally intended to contain a
single item.
[0013] Pocket contents may be accessed at random, or, in certain
instances, in a prescribed sequence.
[0014] A peripheral upstand rim, ledge or ridge may be
incorporated, to help stiffen the overall tray profile.
[0015] Pharmaceutical
[0016] For pharmaceutical use, blister packs are pre-formed
(typically moulded, resiliently deformable, synthetic plastics--eg
PVC (polyvinyl chloride) or aluminum laminates
(polyamide/aluminum/PVC)--shells, with a pre-configured array of
multiple discrete pockets (or blisters), of bespoke contour for
respective individual product items, typically a powder or
granulated base, in tablet or capsule form.
[0017] Tabletted or encapsulated product is captured or restrained
within the pockets, by a releasable, removable or frangible backing
layer, typically of metal (eg aluminum foil), metallized plastics
foil, or a laminated paper and foil combination.
[0018] In a laminated paper and foil combination, the paper is
(adhesive) bonded in a laminated, multi-ply, overlay to the foil,
as a (prisable, or `lift-off`) release layer.
[0019] As such, the paper is intended to protect the underlying
foil while the paper is in situ,
[0020] To that end, the paper is bonded to the foil, and is not
otherwise secured to the blister pack itself.
[0021] In practice, the foil is fused, by heat welding (such as by
a heated profiled platen), to the blister, except for certain
localised areas, say at the edges, which serve as a backing paper
lift-off point for `prise 'n-peel` paper separation and removal
from the foil.
[0022] The paper overlay effectively obscures the foil--and so
impedes localised or `piecemeal` foil and blister separation, as
described later.
[0023] Generally, the paper constitutes a tamper-resistant, and in
particular child-resistant, quasi-`impenetrable` layer, to casual
blister pack contents discharge--say through inquisitive handling
and experimentation.
[0024] Once the paper overlay is prised apart and peeled back from
the foil underlay, over a selected tablet or capsule pocket or
recess in the blister pack, foil puncture is allowed.
[0025] To assist localised peeling of the protective paper backing
layer, it is known to apply a matrix or grid of perforations, say,
upon pack fabrication and assembly.
[0026] Thus local removal of a paper backing cover portion
overlying a particular pocket and local exposure of foil overlying
that pocket, allows contents (such as a tablet or capsule)
displacement and ultimate ejection--upon foil tearing or
rupture--by depressing the relevant resiliently deformable blister
pocket walls.
[0027] Given their construction, blister packs, and particularly
the intentionally frangible (and so fragile) backing foil layer,
are vulnerable to inadvertent (impact or abrasion) contact damage
and consequent unintentional pack rupture and attendant product
fracture, fragmentation, or displacement and loss.
[0028] Thus folding, creasing or crushing, such as may arise by
carrying a foil-backed blister in the pocket, can lead to contents
contamination, displacement and loss altogether.
[0029] Similarly, casual handling by a naturally inquisitive child
can enable accidental contents access--and the risk of hazardous
consumption.
[0030] One aspect of the invention addresses this vulnerability by
the provision of a supplementary protective element--specifically a
card, which also allows a large print surface area for
(multi-lingual) pack directions and information.
[0031] For pharmaceutical packaging, this element may also have an
ancillary role in clinical trials--as described later.
[0032] Paper Backing
[0033] The frailty of foil alone has lead to paper-foil laminates,
in which the foil is effectively afforded a protective backing
layer of more robust and essentially inherently non-tearable
paper.
[0034] Mutually-bonded, paper-foil laminates are generally
prefabricated, before application to packaging machinery.
[0035] Wallet Card
[0036] Paper protective foil backing aside, another protective
counter-measure, is to mount blister packs in juxtaposition with
another element, in particular within a carded `wallet` effectively
a protective envelope, pocket, pouch, wrap or shroud.
[0037] The wallet also provides space for the addition of detailed
text information and patient instructions, to meet regulatory
requirements and promote patient compliance.
[0038] Such a wallet is convenient for personal storage in garment
pockets, handbags, purses or wallets.
[0039] Known such wallet card structures envelope the blister pack,
with card leaves on opposite sides.
[0040] The card wallet can be configured to allow product discharge
without removing the blister pack.
[0041] To this end, one card leaf may incorporate an array of
apertures corresponding to that of the blisters, to allow their
contents locally to penetrate the card.
[0042] In one known card sandwich configuration, a blister pack
entrained between opposed cards may feature corresponding aligned
sets of apertures in both cards, one accommodating the blisters,
the other for product discharge.
[0043] A further protective hinged fly leaf card completes the
wallet to inhibit inadvertent contact discharge.
[0044] The card may literally be of cardboard--ie (relatively thick
and stiff) paper (pulp and fibre) product--or other substitute
materials, including synthetic plastics and multi-layer
composites.
[0045] In a particular--albeit elaborate--walleting method, WO
00/501,511 (Covance), ultrasonic welding is employed to edge bond a
polymer coated card to a blister pack, to prescribed
constraints--namely, a seam width of .ltoreq.8 mm, located
.gtoreq.12 mm from the nearest medicament, and an ultrasound
exposure time of .ltoreq.2 seconds.
[0046] Pharmaceutical Dispensing
[0047] Blister packaging for dispensing pharmaceutical products is
generally favoured over loose product, or bottled tablets or
capsules, in prescription dispensing, for certainty in quantity
dispensed, security of storage and convenience of
consumption--hence improved prospect of compliance.
[0048] Generally, packaging should be comprehensible and accessible
to the elderly, frail and infirm--who may be defeated by certain
child-resistant features.
[0049] Clinical Trials
[0050] It is known to adopt bespoke blister packs for so-called
`clinical trials`--a research technique prior to product launch,
where (comparative and absolute) product performance and dosage
regimes are evaluated in a strictly regulated scheme, over a
designated patient study group, for an assessment of efficacy, side
effects and safety.
[0051] Sometimes a pharmaceutical is substituted by a non-active
product, or so-called `placebo`.
[0052] Information & Instructions
[0053] Information and instructions are commonly printed upon the
blister pack--for example a daily dosage and compliance regime.
[0054] For clinical trials, some provision for return of completed
information, by the patient and/or investigator/clinician may also
be desirable to facilitate evaluation.
[0055] Pack contents layout reflects the strict discipline of
sequential consumption dictated by the trial sponsor.
[0056] Colour and/or shape encoding of tablet or capsule contents
may also be adopted albeit at the risk of unduly complicating the
patient task in compliance with the trial sponsor's intentions.
[0057] Printed indicia on the card--and, according to some aspects
of the invention, optionally also on the foil or paper-backed foil
backing layer--to convey intended contents use, is also
envisaged.
[0058] Production
[0059] Machines dedicated to blister pack production are capable of
high speed operation and are of sophisticated construction.
[0060] Accordingly, their use is only justifiable economically for
long production runs of consistent pack format--that is without
frequent interruption for re-setting.
[0061] However, subsequent blister and card handling, relative
orientation and assembly steps for packaging, pack mounting, or
wallet pack assembly and insertion, are generally more elaborate
and cumbersome--and so much slower to effect.
[0062] Thus blister pack carding may prove either incompatible, or
slow blister pack production, possibly to uneconomic levels, for
short runs, such as may be dictated by clinical trial studies.
[0063] Some aspects of the present invention are concerned to
achieve a carded blister pack capable of high speed assembly, and
the attendant machines and processes.
STATEMENT OF INVENTION
[0064] According to one aspect of the invention,
[0065] a mounting card
[0066] and blister pack,
[0067] are [mutually] edge entrained--
[0068] such as by adhesive bonding.
[0069] Bonding
[0070] Mutual edge bonding is conveniently alongside one or more
spine folds in the card, to facilitate folding over the card, as a
cover hinged about that bonding edge.
[0071] Bonding may be undertaken by applying a (thin) strip of
adhesive alongside one edge of the cover card and affixing a
corresponding edge of the blister pack.
[0072] Adhesive curing or setting can be through various processes,
including `airless` contact, hot melt or chemical interaction or
admixture.
[0073] In the case of twin, chemically interactive, components,
such as epoxy resins, one component may be applied as an edge strip
to the blister pack and the other component to the cover card.
[0074] Thus, for example, a blister pack may be bonded at one edge
to a corresponding opposed edge of a mounting card.
[0075] Mounting card may be cardboard and/or plastics, including
(say, varnish) coated card, or multiple layer card and plastic
(thin) film laminates.
[0076] Mounting card may be translucent (plastics) or opaque.
[0077] A practical problem arises with securing a cover flap to a
foil backed, and in particular paper-foil laminate backed, blister
pack.
[0078] Thus, whilst a sufficient adhesive bond may be formed
between cover and foil, the necessary local `relief`, or peelable
edge exposure, would be obstructed at the spine joint between cover
and blister.
[0079] As the cover is envisaged as suitable for an otherwise
conventional blister pack--allowing assembly on conventional
packaging machinery--minimal blister pack structural adaption would
be desirable for cover mounting according to the invention.
[0080] Thus, in one approach, a paper-backed foil layer is stopped
short of the marginal edge of the blister, to leave an exposed
spine mounting strip.
[0081] The paper-backed foil edge would thus remain exposed
alongside, rather than overlaid by, the inboard cover
edge--allowing local edge prising and peeling back for selective
blister pack contents discharge.
[0082] Removal of a paper backing layer in its entirety would
expose the entire underlying foil and thus the contents of any or
all blister pockets to random access and discharge, upon foil
rupture.
[0083] Local paper backing layer removal is difficult to control,
without supplementary provision, such as pre-perforation around
individual pockets.
[0084] However, access to pockets away from the pack edge requires
an initial free prise 'n-peel edge.
SUPPLEMENTAL STATEMENT OF INVENTION
[0085] According to another aspect of the invention,
[0086] a paper foil backed blister pack
[0087] incorporates one or more access apertures,
[0088] through the paper foil and blister,
[0089] generally at the corners of individual blisters,
[0090] to afford edge `prise 'n-peel` access,
[0091] to local patches of paper backing.
[0092] In practice, around the aperture marginal periphery the
underlying foil would not be heat welded or fused to the
blister.
[0093] This separation creates continuous access edges for local
foil, and attendant localised prise 'n-peel of a patch of paper
backing, over a selected blister pocket
[0094] Peeling for patch removal is in a direction appropriate to
the particular underlying pocket to be exposed.
[0095] Such apertures could be profiled, for example, as pointer
triangles or arrows, to direct such paper and foil peeling.
[0096] Initially, the un-fused foil and bonded paper backing are
prised together away from the blister, until a point is reached
where the foil to blister pack fusion commences, whereupon
continued foil peeling is impeded, but paper backing peeling can be
continued, allowing the paper to separate from the foil.
[0097] In practice, by sub-division of the backing layer into a
mutually entrained patch matrix by a pre-perforation grid, such
paper backing removal is as a local `patch`, over a selected or
target underlying blister pocket.
[0098] In addition, or as an alternative, to paper backed foil,
further child resistant or tamper evident features may be
incorporated, to provide a visible indication that a pack has been
interfered with.
[0099] To that end, the same protective or barrier seals or
locking/latching tabs which inhibit child access could--upon
breakage--provide an irreversible sign of pack opening.
SUPPLEMENTAL STATEMENT OF INVENTION
[0100] According to another aspect of the invention,
[0101] a blister pack and
[0102] cover card (or cover wrap)
[0103] are variously entrained,
[0104] through single or multiple edge bonding,
[0105] to form a closed package,
[0106] which once closed and sealed,
[0107] can only be opened by (visibly) breaking the [tab] seal.
[0108] In practice, a single tab seal could be used for an entire
pack.
[0109] Alternatively, individual portions of a pack could be
separately closed, by respective discrete or severable cover
portions and attendant tab seals.
[0110] Moreover, the closure covers could be contrived as
interactive or interdependent--so that, say, access to covers must
follow a prescribed sequence.
[0111] This could be achieved with partial cover overlay or
interfit, or wholesale internesting or multi-layered covers or
wraps; vis wraps configured within wraps--to allow phased access
and contents discharge for consumption.
[0112] Production
SUPPLEMENTAL STATEMENT OF INVENTION
[0113] A machine for assembly of carded blister packs,
[0114] comprises
[0115] a mounting card storage magazine,
[0116] and a blister pack storage magazine;
[0117] a conveyor for transferring mounting cards,
[0118] discharged individually in succession
[0119] from the mounting card storage magazine,
[0120] through an intervening adhesive application station,
[0121] into juxtaposition with individual blister packs, discharged
individually in succession,
[0122] from the blister pack storage magazine.
[0123] In mass production, a stack of mutually-aligned mounting
cards may be stored in a magazine, ready for sequential discharge
and individual presentation to a designated blister pack.
[0124] Presentation requires mutual alignment of card and blister
pack, together with marginal edge overlap.
[0125] Prior to contact, a layer of (`airless`, contact, hot melt
or chemically cured) adhesive is applied to either, or both, card
and blister--whereupon the corresponding card and blister edges are
pressed and held together.
[0126] Alternatively, mounting card and blister pack may be solvent
bonded, welded or fused, along marginal edge overlap.
[0127] A flat platen or rotary (squeeze) roller, individually or in
mutual opposition, may be used, with local pressure application, by
virtue of the surface profile.
[0128] In a folding station, the card is turned to overlie, or
underlie, the blister pack--forming a book jacket, with one panel
of card and the other of blister pack.
[0129] Folding may be prefaced by preliminary creasing, or scoring,
about a fold line, locally to weaken the material and pre-dispose
it to `clean` folding, that is without wrinkles or creases.
[0130] In practice, the fold line can lie within the card, and
(just at or) beyond the blister pack margins--leaving the blister
itself intact.
[0131] The card thickness is chosen to provide sufficient residual
mechanical robustness upon folding.
[0132] A score or perforation line may be incorporated--again most
conveniently in the card itself--to facilitate detachment of the
card from the blister.
[0133] In a particular construction, a (discharge) conveyor carries
the carded blister assembly away from the jointing or joint bonding
station, to an optional folding area and thence to a collating
station.
[0134] At a collating station, the carded blisters are discharged
and stacked in succession, ready for transit and storage.
[0135] The cards--and indeed the blister packs--may be pre-printed
before assembly, or printed at a printing station as an integrated
step in the assembly sequence.
[0136] Assembly integrated printing may be of additional
information, such as a batch code and date identifier, upon an
otherwise pre-printed card and/or blister pack.
[0137] One carded blister pack variant is configured as a book
jacket, with a central (mounting) spine, overlaid with adhesive,
for attachment to an edge of a (preformed or pre-fabricated)
blister pack, and card panels disposed as opposed leaves about the
spine, with folds or creases, to allow mutual over-folding.
[0138] In such a configuration, either or both panels or leaves may
be severed from a residual spine by a pre-formed perforation or
score line.
[0139] For ease of mechanised assembly, one panel may be out-turned
and folded back upon itself, about a spine edge, to underlie the
other, and present the spine and a locally overlaid adhesive layer
for blister pack mounting.
[0140] So presented, the folded double card or book jacket thus
equates to the single card mounting configuration.
[0141] The out-turned panel is return folded back about the spine
to underlie the blister pack once mounted.
[0142] Multiple--similar or disparate--blister packs may be mounted
upon a common spine.
[0143] Moreover, multiple spines may be employed.
[0144] An example would be mutually concertina-folded spines, with
respective blister pack mounting strips.
[0145] Spines may be stacked overlying and/or mutually staggered or
laterally offset for ease of folding and access.
EMBODIMENTS
[0146] There now follows a description of some particular
embodiments of the invention, by way of example only, with
reference to the accompanying diagrammatic and schematic drawings,
in which:
[0147] Cover Card Variants
[0148] FIGS. 1A through 1D show successive assembly, folding over
and closing together stages for a carded blister pack;
[0149] More specifically:
[0150] FIG. 1A shows juxtaposition of a discrete card element and a
blister pack to be entrained thereby, with marginal corresponding
edge overlap;
[0151] FIG. 1B shows an assembled card and blister pack, with
marginal overlapped edges mutually bonded;
[0152] FIG. 1C shows an initial stage of card element folding,
about a crease line, alongside a (adhesively) bonded spine
portion;
[0153] FIG. 1D shows closure of the card element to overlie the
blister pack, as a book, book cover (leaf) or book jacket
configuration;
[0154] FIGS. 2A and 2B show a variant of FIGS. 1A through 1D with
severable card element through a perforation line;
[0155] More specifically:
[0156] FIG. 2A shows an assembled card and blister pack with
marginal overlapped edges mutually bonded, with optional
perforation to allow separation of cover and panel element;
[0157] FIG. 2B shows closure of card element to overlie the blister
pack, and initial stages of cover card removal by severance along
perforations;
[0158] FIGS. 3A through 3C show successive stages in assembly of a
variant carded blister construction to that of FIGS. 1A through
2B;
[0159] More specifically:
[0160] FIG. 3A shows juxtaposed fragmentary views of a
double-panelled card (in the form of a book jacket) and a blister
pack, with an edge overlapped upon a central spine strip, with
optional perforations to allow severance of panelled card
elements;
[0161] FIG. 3B shows an assembled, open, double card packet) and
blister pack, with panel element underlying blister pack folded
back, along a spine edge, to allow ejection of blister pack
contents;
[0162] FIG. 3C shows an assembled double card (jacket) and blister
pack, with one panelled element severed along a spine edge and
separated;
[0163] FIGS. 4A through 4C show variant configurations of carded
blister pack to those of FIGS. 1A through 3B;
[0164] More specifically:
[0165] FIG. 4A shows a semicircular carded blister pack
profile;
[0166] FIG. 4B shows a triangular carded blister pack profile, with
differently profiled blisters, disposed in a pattern array; and
[0167] FIG. 4C shows a waisted, curvilinear carded blister pack
(dumbbell) profile;
[0168] FIGS. 5A through 5D show successive assembly stages of a
multiple-spine, carded blister variant, in which stacked,
mutually-overlapping spine folds are entrained to respective
individual blister packs;
[0169] More specifically:
[0170] FIG. 5A shows a multiple-spine mounting card, with spine
segments (presenting attendant adhesive strips) spread apart and
juxtaposed with respective multiple individual blister packs;
[0171] FIG. 5B shows the multiple-spine mounting card of FIG. 5A
with blister packs located upon respective individual spine
segments;
[0172] FIG. 5C shows concertina-folding, into a
mutually-overlapping stack, of the (splayed) spine segments of
FIGS. 5A and 5B;
[0173] FIG. 5D shows full closure of the single card mounted
multiple blister pack assembly, following the steps of FIGS. 5A
through 5C;
[0174] FIGS. 6A through 6D show corresponding assembly and closure
stages, for a multiple-spine, carded blister variant of FIGS. 5A
through 5D, in which successive spine folds are somewhat staggered,
or mutually-offset laterally, to provide staggered exposed blister
leaves--for ease of selection and access upon closure;
[0175] More specifically:
[0176] FIG. 6A shows a multiple-spine mounting card with
differential width spine segments (presenting attendant adhesive
strips), juxtaposed with multiple individual blister packs;
[0177] FIG. 6B shows the multiple-spine mounting card of FIG. 6A
with blister packs disposed (in situ), in laterally staggered or
mutually offset relative positions, upon respective individual
spine segments;
[0178] FIG. 6C shows concertina-folding, into a mutually
part-overlapping, progressively marginally offset, stack of the
spine segments of FIGS. 6A and 6B;
[0179] FIG. 6D shows full closure of the single card mounted
multiple blister pack assembly following the steps of FIGS. 6A
through 6C, with successive stacked blister packs marginally
laterally offset, to present exposed outer edges, in the manner of
a card index file.
[0180] FIGS. 7A through 7D show successive assembly and closure
stages for a single spine, single card, multiple blister pack
variant, in which multiple individual blister packs--in this
example of generally similar rectangular form--are mounted in
tandem, juxtaposed upon respective adhesive pads, spread (evenly)
along a common spine;
[0181] More specifically:
[0182] FIG. 7A shows an initial stage in juxtaposition of multiple
individual blister packs upon respective adhesive mounting
pads;
[0183] FIG. 7B shows the multiple blister packs of FIG. 7A overlaid
upon the common card spine; the blister packs could be mounted
simultaneously under one press tool (not shown) or successively, by
relative displacement of the assembly and/or tool;
[0184] FIG. 7C shows the common (multiple blister pack) mounting
card folded about the common spine;
[0185] FIG. 7D shows conclusion of card folding of FIG. 7C to form
a common cover for multiple blister packs;
[0186] FIGS. 8A and 8B show a variant configuration of a
multiple-spine carded blister pack of FIGS. 5A through 5C,
employing disparate blister pack configurations.
[0187] More specifically:
[0188] FIG. 8A shows a multiple-spine mounting card, with disparate
blister packs--triangular, rectangular, and semi-circular--located
upon respective individual spine segments;
[0189] FIG. 8B shows concertina folding, into a mutually
overlapping stack, of the (splayed) spine segments and closure of
the common card cover of FIG. 8A;
[0190] FIGS. 9A and 9B show a variant configuration of a single
spine, single card, multiple blister pack of FIGS. 7A through
7D;
[0191] More specifically:
[0192] FIG. 9A shows multiple triangular blister packs mounted upon
a common spine of triangular card;
[0193] FIG. 9B shows closure of the common triangular cover card
over multiple, entrained, triangular blister packs.
[0194] FIG. 10 shows a part-sectioned, part cut-away, side
elevation of a bespoke machine for assembly of carded blister packs
according to FIGS. 1A through 9B;
[0195] FIGS. 11(1) through 11(6) show successive stages, designated
(1) through (6) respectively in FIG. 10, in assembly of a single
blister pack upon a mounting card, such as by using the machine of
FIG. 10;
[0196] More specifically:
[0197] FIG. 11(1) shows a mounting card initially deposited upon a
conveyor from an overhead stacked storage magazine;
[0198] FIG. 11(2) shows the mounting card of FIG. 11(1) placed on
the conveyor, its presence is confirmed, and then transferred along
the conveyor;
[0199] FIG. 11(3) shows deposition of a strip of adhesive, from a
discharge gun, upon the spine of the mounting cards of FIGS. 11(1)
and 11(2);
[0200] FIG. 11(4) shows deposition of a blister pack, discharged
from an overhead stacked storage magazine, upon the mounting card
with adhesive coated spine achieved in FIG. 11(3);
[0201] FIG. 11(5) shows a compression platen, or press compaction,
of the adhesive bonded blister pack and mounting card of FIG.
11(4);
[0202] FIG. 11(6) shows optional further compression and/or spine
folding for the card mounted blister of FIG. 11(5), prior to card
blister discharge (7) FIG. 10;
[0203] Paper-Backed Foil Variants
[0204] FIGS. 12A through 12E--of which FIGS. 12A and 12B are 3-D
perspective views and FIGS. 12C through 12E are local enlarged
cross-sections--show a paper foil backed blister pack, with edge
spine bonded folded cover card, incorporating through apertures and
perforations, for selective prising and peeling (`prise 'n-peel`)
of local paper patches over individual blisters or blister
pockets;
[0205] More specifically:
[0206] FIG. 12A shows juxtaposed fragmentary views of one (under)
side of a paper foil backing layer, with alternative modes of edge
spine attachment for a cover card, itself folded back upon itself
somewhat, for ease of illustration; and
[0207] FIG. 12B shows an opposite side blister tray, which the
cover is intended to overlay when closed, but with the cover card
omitted, again for ease of illustration;
[0208] FIGS. 12C and 12D detail, on an enlarged scale, the
alternative modes of cover card edge spine attachment depicted to
opposite sides of FIG. 12A;
[0209] Thus FIG. 12C depicts cover card attachment, by an adhesive
bonding strip direct to the paper backing layer,
[0210] FIG. 12D depicts cover card attachment, by an adhesive
bonding strip, direct to the blister pack itself, with the paper
backed foil marginally inset from the blister pack edge, to
accommodate the spine joint;
[0211] FIG. 12E depicts, on a still further enlarged scale, a
marginal peripheral (prise 'n-peel) rim, formed around each of the
apertures through the back assembly, by terminating the (heat) weld
fusion between foil and blister locally around the aperture;
[0212] FIGS. 13A through 13D are 3-D perspective views,
corresponding to FIG. 12A, of the blister and cover card of FIGS.
12A through 12E, depicted in successive stages of selective
contents access.
[0213] Access is through targeted localised protective `patch`
prise 'n-peel, initially of the paper backing, and then rupture of
the underlying foil.
[0214] Foil penetration is by distortion of a selected individual
pocket, to displace the pocket (tablet or capsule) contents through
the foil and eject it altogether from the blister,
[0215] More specifically.
[0216] FIG. 13A shows local paper patch prise 'n-peel from an
aperture at a corner of an underlying blister pocket;
[0217] FIG. 13B shows a continuation of the FIG. 13A step, with
wholesale patch peeling back for separation and removal, to expose
the underlying foil over a target blister pocket;
[0218] FIG. 13C shows exposed foil tearing and rupture by
deformation of the target blister pocket walls;
[0219] FIG. 13D shows displacement and discharge of the target
blister pocket (tablet or capsule) contents;
[0220] FIGS. 14A through 14D depict 3-D perspective views,
corresponding to FIG. 12A and FIGS. 13A through 13D of bespoke
through aperture edge profile or bounding contour treatment, to
facilitate location, orientation and prising apart of protective
paper backing from underlying foil;
[0221] More specifically,
[0222] FIG. 14A depicts a diamond shaped apertures;
[0223] FIG. 14B depicts star-shaped apertures--with a curved edge
leaf inviting diagonal prise 'n-peel of a patch of paper
backing;
[0224] FIG. 14C depicts a `mix 'n match` combination of diverse
aperture shapes, in a distinctive pattern, to assist blister pocket
identification;
[0225] FIG. 14D is a refinement of FIG. 14C with even more
elaborate aperture profiling to enable visual and/or machine
readable encoding and user direction, such as blister access for
consumption sequence;
[0226] FIGS. 15A through 15E depict stages in aperture, formation,
by (multiple) punch and die cutting, in this instance from the
blister underside, corresponding to a typical orientation of the
blister pack in pack assembly machinery; FIGS. 15D and E are 3-D
perspective views, as in FIGS. 12A and 12B.
[0227] That said, tool and pack orientation may be varied according
to packaging machine configuration.
[0228] More specifically:
[0229] FIG. 15A depicts a mutually-aligned punch tool--[albeit for
ease of illustration showing only an individual one of multiple pin
heads mounted upon a common platen]--complementary die bed and
intervening paper foil backed blister, disposed at the corner of
adjoining blister pockets;
[0230] FIG. 15B shows die penetration of the blister pack and paper
foil backing, with waste cut-out portion displacement and discharge
through the die aperture; in practice a complete set of cut-out
apertures can be punched simultaneously, in a single tool
stroke;
[0231] FIG. 15C shows die punch retraction, to allow punched
blister removal from the tool path(s), say by indexed conveyor
output progression to a subsequent process stage, and substitution
by a fresh unpunched blister pack;
[0232] In practice, such aperture punching could be undertaken
simultaneously, or sequentially, with that for perforation
(tear-off) lines, as described later.
[0233] FIG. 15D depicts a punch tool with multiple pin heads
aligned for multiple aperture formation in a paper foil backed
blister pack, optional smaller pin heads allow the addition of
perforations, typically only in the paper and foil layer.
[0234] FIG. 15E shows a blister pack with cut out apertures between
blister pockets, and optional perforation of the paper foil backing
layer.
[0235] FIGS. 16A through 16C depict differential shape and/or size
blister and paper foil backing layer aperture profiles, to create a
(segmented) edge `reveal` around each blister aperture; that is the
paper foil is inset marginally within the aperture, to allow prise
'n-peel purchase with a user's finger (nail);
[0236] FIGS. 16A and 16B are 3-D perspective views from opposite
sides, as in FIGS. 12A and 12B; and
[0237] FIG. 16C is a localised sectional view, on an enlarged
scale, through an individual aperture and immediately surrounding
blister pack;
[0238] More specifically,
[0239] FIG. 16A shows a paper foil side, with an array of apertures
of one shape and size--somewhat smaller than corresponding aligned
apertures in the blister itself.
[0240] The blister holes may be integrally moulded upon blister
formation, or punched before contents fill and application of paper
foil backing layer;
[0241] FIG. 16B shows the opposite blister side to FIG. 16A,
revealing a marginal edge protrusion of paper foil within the
blister apertures;
[0242] FIG. 16C shows an enlarged scrap or fragmentary section A-A
differential aligned apertures in paper foil and blister, to create
a paper foil `overhang`, as a marginal starting edge for paper
prise 'n-peel.
[0243] FIGS. 17A through 17E show die punching for the dual
aperture configurations of FIGS. 16A through 16C; of these FIGS.
17A and 17B are 3-D perspective views of opposite sides of a
blister (any cover card being omitted for ease of illustration) and
FIGS. 17C through 17E are enlarged local sectional views of blister
and paper foil backing penetration with a (multi-head) die punch
tool;
[0244] More specifically,
[0245] FIG. 17A shows a paper foil layer overlaying a pre-punched
blister;
[0246] FIG. 17B shows a pre-punched blister, with apertures covered
on one side by an unpunctured, continuous, paper foil layer;
[0247] FIG. 17C shows a stepped-profile die punch tool aligned over
a pre-punched blister aperture, ready to penetrate the paper foil
backing;
[0248] FIG. 17D shows punching action, with interfit of an
individual punch tool and complementary die aperture, with
displacement of paper foil waste disc;
[0249] FIG. 17E shows punch tool retraction, leaving mutually
aligned apertures of different span respectively in the paper foil
and blister pack layers;
[0250] FIGS. 18A and 18B show an alternative approach for selective
blister pack individual contents removal, using a bespoke tool;
[0251] More specifically,
[0252] FIG. 18A shows a `discharge` tool or key, with a cutter
enabling local penetration of paper reinforced foil;
[0253] FIG. 18B shows a bespoke, complementary profiled side to the
blister pack configured for selective interaction and interfit with
the key of FIG. 18A; the blister profile incorporates a juxtaposed
blister pocket, for an individual tablet or capsule and a through
aperture, to receive a (paper) foil cutter blade upstand upon the
key;
[0254] FIGS. 19A through 19D show successive steps in using the
tool to access the contents of the blister pack of FIGS. 18A and
18B;
[0255] More specifically,
[0256] FIG. 19A shows an initial step of mutual alignment of a
blister pack with an individual blister pocket contents discharge
tool or key, configured as a recessed, indented or scalloped plate,
whose recess profile corresponds to that of an individual blister
pocket, with a knife cutter upstand, for location in the
corresponding profile local aperture in the blister, for local foil
(and optionally also reinforcement backing paper) penetration;
[0257] FIG. 19B shows the discharge tool pressed against an
individual blister pocket, so that the cutter penetrates the
(paper) foil overlayer;
[0258] FIG. 19C shows key removal;
[0259] FIG. 19D shows tearing and/or peeling back of the punctured
(paper) foil, to expose an individual blister pocket contents; the
key could also be used to deform or distort, the pocket wall
itself, by say, crushing or reverse, in-turn folding, say, upon
tool reversal or through adoption of a shallower tool recess;
[0260] Child Resistant Covers
[0261] FIGS. 20A through 23F show variant child-resistant and/or
tamper-evident pack configurations, with cover card edge bonding of
FIGS. 1A through 3B.
[0262] Although not detailed, the paper foil backing--with access
aperture variants of FIGS. 12A through 19D herein--can be
incorporated, as a supplementary feature.
[0263] FIGS. 20A through 20E show successive assembly stages for a
blister pack and a cover card bonded to one longitudinal edge and a
closure flap, with latching tab, bonded to the opposite side;
[0264] More specifically:
[0265] FIG. 20A shows preliminary juxtaposition of a blister pack
and a rectangular cover card element, with closure slot, to one
side and discrete second card element, with locking tab seal, to be
entrained thereby through tab insertion into the slot, with
residual marginal edge overlap;
[0266] FIG. 20B shows an assembled card and blister pack, with
opposite marginal edges respectively bonded to cover card
elements;
[0267] FIG. 20C shows the card and blister pack assembly of FIG.
20B, with the rectangular card folded, about a crease line,
alongside an adhesively bonded spine portion, to overlie the
blister;
[0268] FIG. 20D shows the card and blister pack assembly of FIG.
20C with the locking tab folded over and partially inserted into
the slot in the rectangular cover card element;
[0269] FIG. 20E shows the card and blister pack assembly of FIG.
20D fully closed;
[0270] The re-entrant or waisted profile of the locking tab nose,
in relation to the slot profile, means that it cannot be readily
withdrawn from, once fully inserted into, the slot--without tab
severance, such as by tearing off the nose.
[0271] FIGS. 21A through 21G show a variant locking tab seal
configuration of FIGS. 20A through 20E, using a single edge bonded
folded cover card and a discrete floating locking tab--also
entrained by edge bonding at the opposite side of the blister to
the cover card;
[0272] More specifically,
[0273] FIG. 21A shows juxtaposed blister pack, cover card and
locking tab seal;
[0274] FIG. 21B shows initial inter-assembly of cover card and
blister pack;
[0275] FIG. 21C shows folding over of the assembled cover card and
blister pack of FIG. 21B;
[0276] FIG. 21D shows fitmet of the tab seal in the assembly of
FIG. 21C;
[0277] FIG. 21E shows tab sealing;
[0278] FIG. 21F shows the sealed pack;
[0279] FIG. 21G shows tab seal fracture and removal, to allow cover
card opening and pack access
[0280] FIGS. 22A through 22H show a variant triple panel element
(vis opposed side and lid) cover card configuration, allowing four
sided blister attachment;
[0281] More specifically,
[0282] FIG. 22A shows juxta-posed triple-panel element cover card
and blister pack, with provision for adhesive edge bonding of each
panel along a respective spine fold, and corresponding blister
edge;
[0283] FIG. 22B shows the constituents of FIG. 22A in a bonded,
open-pack, assembly;
[0284] FIG. 22C shows initial in-folding of side panel elements of
the assembly of FIG. 22B;
[0285] FIG. 22D shows over folding of the lid cover panel and
depending lip of the folded assembly of FIG. 22C;
[0286] FIG. 22E shows closure lip in-turn and bonded edge sealing
of the assembly of
[0287] FIG. 22D--to achieve an overall pack closure seal;
[0288] FIG. 22F shows partial tear-off seal tab removal of the pack
of FIG. 22E;
[0289] FIG. 22G shows pack unsealing, by wholesale tab severance
and removal, to allow opening and contents access of the pack of
FIG. 22F;
[0290] FIG. 22H shows pack opening, by lid and side panel unfolding
of the unsealed pack of FIG. 22G;
[0291] FIGS. 23A through 23F show a blister pack and cover card
with twin opposed side leaves and respective edge spine sealing, to
achieve a cover sleeve configuration;
[0292] More specifically,
[0293] FIG. 23A shows juxtaposed cover sleeve and blister pack;
[0294] FIG. 23B shows initial positioning for opposed edge sealing
of the juxtaposed elements of FIG. 23A;
[0295] FIG. 23C shows cover sleeve opposed edge in-turn and
sealing, by adhesive spine bonding, closure of the assembly of FIG.
23B;
[0296] FIG. 23D shows initial tear-off (face cover) seal tab
removal of the cover sleeve and blister assembly of FIG. 23C,
[0297] FIG. 23E shows tab seal separation and removal to allow
opening of the unsealed assembly of FIG. 23E;
[0298] FIG. 23F shows sleeve face cover opening, by folding about
one entrained side edge, of the assembly of FIG. 23E, for contents
access.
[0299] Referring to the drawings--in particular FIGS. 1A through
2B--a carded, or card mounted, (single) blister pack assembly 20
comprises a mutually-entrained card element 12 and pre-formed (and
pre-filled and sealed) individual blister pack 11.
[0300] The blister pack element 11 comprises a plastics sheet 17,
with an array of pre-formed discrete pockets or compartments 18,
backed by a frangible layer of metal toil 19.
[0301] The card element 12 comprises a panel 14, a (double) hinged
spine segment 15 and an adhesive (peripheral) edge mounting strip
16.
[0302] A crease or fold line 29 separates or sub-divides the
mounting strip 16 from the spine segment 15.
[0303] Similarly, a crease or fold line 28 separates or sub-divides
the spine segment 15 from the panel 14.
[0304] An optional perforation line 13 is marginally inset from the
crease 28.
[0305] The panel 14 and spine segment 15 can be separated by a
relative tearing action along this perforation line 13.
[0306] Crease or fold lines 28, 29 may themselves by perforated to
allow removal of panel 14.
[0307] A corresponding double card(ed) 22A, 22B, blister pack
variant, as shown in FIGS. 3A through 3C, includes two removable
card panels 24A, 24B.
[0308] Access to blister 18 contents may be achieved by folding
back panel 24B, underlying blister pack 17.
[0309] Alternatively, panels 24A, 24B can be severed along
respective perforation lines 23A and 23B, offset marginally from a
(double) hinged intervening spine 25, and adhesive strip 26.
[0310] The mounting strip 16 can be regarded as an entrained (rear)
binding or peripheral edge portion of an overall mounting
spine.
[0311] The hinged spine segment 15 performs a (upstand) spacer role
in the final assembly of card and blister pack, as shown in FIG.
1D.
[0312] Mutual entrainment of card element 12 and blister pack 11 is
through respective marginal edge overlap, by the width of the
mounting strip 16.
[0313] Adhesive or bonding agent--such as hot melt glue--is applied
over a prescribed portion of the mounting strip 16 as a mounting
pad.
[0314] A continuous line of adhesive, and/or multiple discrete pads
(not shown), may be employed.
[0315] The adhesive 16 may be a tacky, contact, multi-component (eg
two-part epoxy) or impact (airless setting) type, or hot
melt--requiring heat application to activate and cooling to
harden.
[0316] Adhesive, or bonding agent, is conveniently applied to the
card 12, but may instead, or additionally, be applied to the
blister pack 11 itself.
[0317] In this case, the card element 12 is of cardboard (ie a
paper, or pulped fibre type of product), of a thickness or gauge
and constitution sufficient to impart a desired stiffness, for a
role of protective cover.
[0318] However, synthetic plastics sheet material may supplement,
reinforce or substitute for cardboard.
[0319] Composite, fibre-reinforced or laminated constructions may
be used.
[0320] The cardboard may be (surface) coated or sealed, for example
by varnish coating or laminated film covering (not shown), for
moisture resistance.
[0321] Single-Spine, Multiple Blister Pack
[0322] FIGS. 1A through 4C show single-spine, single carded blister
pack configurations.
[0323] In particular, FIGS. 4A through 4C show disparate blister
pack contours, in particular, triangular 42, semicircular 43 and
dumb-bell 44, embodying disparate individual blister forms 82, 83,
84 respectively.
[0324] For a single-spine, multiple blister pack variant, the
mounting strip 16 length of a single (common) mounting card 14
could be sub-divided into mounting portions 31, 32, 33 as shown in
FIGS. 7A through 7D.
[0325] These spine mounting portions could in turn be allocated to
different individual blister packs 11.
[0326] The packs 11 themselves could be correspondingly smaller in
span, or incorporate small-span protruding mounting tabs.
[0327] Again, disparate individual pack profiles and/or blister
forms could be employed, as with FIGS. 4A through 4C.
[0328] FIGS. 7A through 7D and 9A, 9B show variant such blister
pack combinations upon a common spine.
[0329] Multiple Spine
[0330] The assembly sequences of FIGS. 5A through 5D, 6A through
6D, and 8A, 8B, show variant multiple-spine, (single or common)
carded blister assemblies.
[0331] A single mounting card 12 is concertina--folded at one side
into multiple spine segments 61, 63, 65--alternating with
intervening adhesive mounting strips 62, 64, 66.
[0332] One (or more) blister packs 11 is allocated to each spine
segment 61, 63, 65, or rather the attendant juxtaposed adhesive
mounting strip 62, 64, 66.
[0333] In an initial mounting configuration--reflected in FIGS. 5A
and 5B--card and spine segments 61 63, 65 are laid flat, or
slightly stepped and mutually offset laterally.
[0334] The mounting strips 62, 64, 66 are thus presented somewhat
spread apart, ready for mounting respective blister packs 11.
[0335] Upon blister pack 11 mounting, the spine segments and
intervening mounting strips 61 through 66 are concertina-folded
into a stacked overlying array, as reflected in FIG. 5A.
[0336] Folding over the (face/cover) card panel 14 to overlie the
stack, as represented in FIG. 5D, completes the assembly 70.
[0337] In this way, a multiple (independent) leaf book array of
blister packs 11 can be achieved, as reflected in FIGS. 5C and
5D.
[0338] A slight spine segment `splay` accommodates the depth of
each individual blister pack 11, without straining the spine or
distorting the stack.
[0339] FIGS. 8A, 8B show disparate profile blister packs 51, 52, 53
mounted upon respective spine segments.
[0340] Thus blister pack 51 has a rectangular profile, as with the
blister packs 11 of FIGS. 1A through 3B and 5A through 7D.
[0341] On the other hand, blister pack 52 has a triangular profile,
apex outward, as with the blister packs of FIGS. 4B and 9A, 9B.
[0342] Further blister pack 53 has a concave curved outer edge
profile, as with the semicircular blister pack of FIG. 4A.
[0343] The blister packs 51 through 53 can thus readily be
differentiated (indeed by touch alone)--for ease of identification
when different products are presented.
[0344] As with FIGS. 4A through 4C, or indeed any of the variants
depicted, different product shapes and sizes, conveniently
representing different ingredient products, may be presented upon
the same of different blister packs.
[0345] Staggered Stack
[0346] For ease of access to individual blister pack (leaves) in a
multiple carded stack, they could be staggered, or marginally
offset laterally, as depicted in FIGS. 6A through 6D, by adopting a
progressively varied spine segment width or depth.
[0347] This preserves a common master binding edge 72 when the
overall pack assembly 70 is closed, yet allows the opposite free
edges 73, 74, 75 of the blister pack leaves to protrude
differentially, in the manner of a card index--as reflected in FIG.
6D.
[0348] Diverse permutations and combinations of segmented spine
mounting, concertina spine segment folding, and pack outline
contour variations could be employed although not illustrated.
[0349] As evoked in FIG. 10, yet another aspect of the invention
addresses a bespoke or dedicated (cartoner, or cartoning) machine,
for assembling mounting cards and blister packs.
[0350] In practice, it is envisaged that cards and blister packs
would be produced (prefabricated) elsewhere and loaded,
cartridge-fashion into stacked storage magazines from which the
machine incrementally draws off stock.
[0351] Magazine contents may be drawn from the stack top or bottom
(as illustrated).
[0352] The cards could be pre-creased, pre-scored or folded, and
pre-perforated, or some of these features could be introduced as
machine stages, prior to and/or after assembly with a blister
pack.
[0353] Similarly, post-assembly, the card cover may be left flat,
or folded to overlie the entrained blister pack, by an additional
machine stage, prior to discharge.
[0354] A printing station (not shown) may be employed, to add local
date/time, content and batch code, as part of a production audit
trail.
[0355] Space is left on the card and/or blister pack (aside from
any generalised pre-printing) for such local data printing.
[0356] The card blister assembly may be discharged to a separate
(cartoner) packing stage--for insertion into a final overall wrap
or carton, along with a Patient Information Leaflet (PIL).
[0357] Assembly of mounting card and blister is a matter of precise
incremental indexing, (linear) alignment, layer deposition,
juxtaposition and closing of elements.
[0358] As such, assembly may be undertaken reliably and
consistently at high speed, but in short batch runs.
[0359] The attendant production economics are suitable for bespoke
carded blister packs as required for low-volume clinical
trials.
[0360] Similar assembly principles may be adopted for the multiple
(similar or disparate) blister packs upon a common spine, or single
or multiple (similar or disparate) blister packs upon stacked spine
variants, addressed FIGS. 1A through 9B.
[0361] For ease of access and assembly, pack installation can be
undertaken with multiple individual spine segments pulled apart and
laid flat.
[0362] Effectively, a repeat of single blister pack single card
mounting step is undertaken for each spine and each blister pack
location.
[0363] The more complex corrugated spine fold configuration is
adopted after assembly.
[0364] Child Resistant
[0365] Tamper and in particular child resistant features may be
embodied into a blister pack, as required by local regulation, in
various formats.
[0366] One format--of FIGS. 12A through 19D--uses an adaptation of
a (relatively robust) protective paper backing overlay to a
(relatively frail) foil underlay.
[0367] Paper backed foil, or simply paper foil, is known per se,
but some packing adaptation is required for its use with a cover
card according to the invention.
[0368] Another format--of FIGS. 20A through 23F--uses mechanical
(latching) coupling of a card cover overlay--such as with a locking
tab seal.
[0369] Aspects of both formats may be combined--for example in a
paper foil backed blister with a card cover and optional cover
latching.
[0370] Tamper Evident
[0371] The child resistant features may be adapted or combined with
tamper evident features--to provide a visible indication that a
pack has been interfered with.
[0372] To that end, the same protective or barrier seals or
locking/latching tabs which inhibit child access could--upon
breakage--provide an irreversible sign of pack opening.
[0373] Paper Backed Foil
[0374] FIGS. 12A through 14D depict the use of paper
(reinforcement) backed foil to import child-resistance.
[0375] More particularly, a laminated (dual layer) paper-backed
foil 161, integrates a frangible foil with a paper reinforcement
overlay, impeding foil rupture or tearing, until separated (by say
peeling back) from the foil.
[0376] The paper reinforcement layer 164 is (adhesive) bonded to
the foil layer 167, which is itself heat welded to the blister pack
162.
[0377] Peel back and separation of the paper 164, over a prescribed
local area, designated a `patch` 169, reveals foil 167 `closing` a
blister pocket 168.
[0378] Local edge `prise 'n-peel` access to the foil 167 and thus
the paper 164, is afforded by series of apertures 166 (penetrating)
through the combined pack thickness.
[0379] These apertures 166 could be die cut, such as by a profiled
(press) platen tool, as shown in FIGS. 15A through 15E.
[0380] The foil 167 is not bonded to the blister pack 162 either at
or adjacent the immediate periphery of the apertures 166.
[0381] These marginal `free` foil regions creates a formative
`prise 'n-peel (back)` rim 160, as a starting point for local
backing sheet removal.
[0382] The apertures 166 are located at, or rather adjacent, the
junction of juxtaposed blister pockets 168, and are disposed in a
complementary rectangular matrix array.
[0383] The apertures 166 thus give some indication of the
underlying blister pocket 168 layout.
[0384] The apertures 166 may be generally circular in form, to
afford uniform peripheral edge access and admit peel-back
`departure` of the paper 164 from the foil 167 in any
direction.
[0385] Alternatively, the apertures 166 may be shaped, say, as
diamond profiles 182, star shapes 183, octagonal shapes 184, or
more elaborately as letters 186 or numbers 187 to help orientate a
user to one or more particular directions, such as rows or
columns.
[0386] Lines of backing layer perforations, are disposed in a
regular rectangular grid array of rows 163 and columns 165,
representing the boundaries of the underlying blister pockets 168,
and define localised `patches` 169, of paper backed foil 161,
juxtaposed over individual pockets 168.
[0387] The perforations 163, 165 extend through at least a paper
backing layer 164, if not also the underlying foil 167, of the
paper foil laminate or sandwich 161.
[0388] As shown in FIGS. 15D and 15E, perforations 163, 165 may be
produced by a punch tool 211, such as a needle profile platen or
rotary needle, upon pack assembly.
[0389] Local patches 169 of backing layer 161, bordered by
successive perforation rows 163 and columns 165 and intervening
corner apertures 166, overly blister pockets 168.
[0390] An individual blister pocket 168 can thus be identified and
its respective paper foil overlay 161 located and peeled back from
one of the bordering corner apertures 166.
[0391] Cover Sheet
[0392] FIGS. 12A, 12C and 12D show two alternative approaches to
paper foil edge access at a cover spine.
[0393] In one approach, a cover sheet 171, with a folded mounting
strip 172, could be (adhesive) bonded at 177, direct to the foil
itself, or the paper backing.
[0394] A line of perforations 173 is introduced alongside and
marginally inset from the mounting strip bond 177.
[0395] The perforations are interrupted by spaced apertures 176 at
the blister row or column boundaries.
[0396] These apertures 176 could be semi-circular in profile, for
edge `prise 'n-peel` separation of the paper backing 164 from the
underlying foil 167, in a direction away from the mounting strip
172.
[0397] In another approach, the paper foil 161 stops short of the
blister pack 162 peripheral edge, to allow direct bonding 179 of a
cover mounting strip 172 to the blister itself.
[0398] In this case, at the paper foil edge 174 adjacent the
mounting strip joint, an underlying foil 167 edge reveal 175 is
created by leaving short of the edge heat fusion to the underlying
blister 162.
[0399] This would be a starting line for edge prise 'n-peel of the
overlying paper (reinforcement) layer 164.
[0400] Localised removal of protective paper backing 164 from an
individual `patch` 169, defined by perforations 163, 165, permits
selective access to blister pocket 168 contents.
[0401] In practice, the paper layer 164 may be prised 'n-peeled
starting at the rim 160 of aperture 166 to expose the underlying
foil layer 167.
[0402] Subsequent pressure applied to the selected individual
blister pocket 168, causes rupture of the foil layer 167 and
ejection of the tablet/capsule contents 170.
[0403] In a particular example, apertures 166 in the blister pack
162 and paper foil layer 161, are formed simultaneously using a
punch cutter 191 and die 192.
[0404] The punch cutter 191 penetrates, and cuts, the paper 164,
foil, 167 and blister pack 162, to locate in a die aperture 194,
cut-out portions 196 are discarded.
[0405] Multiple apertures may be simultaneously punched using a
punch tool comprising a plate 211, with multiple cutters 209.
[0406] In addition, pins 212 may be located on the punch cutter
plate 211, to make perforations 214--typically only through the
paper and foil layer 161.
[0407] An alternative aperture profile 226, as depicted in FIGS.
16A through 16C, is configured such that the aperture 224, in the
blister pack 162, is somewhat larger in diameter than the aperture
225 in the paper backed foil 161.
[0408] As a result, an edge `reveal` 228 is created, where the
paper backed foil 161 is inset marginally within the blister pack
aperture 224, and can thus be accessed for prise 'n-peel removal of
the paper layer.
[0409] Apertures 224 in the blister pack may be pre-made, say, at
the vacuum moulding stage, whilst apertures 225 in the paper backed
foil 161, are made after heat sealing of the foil to the blister
pack.
[0410] FIGS. 17C though 17E depict use of a punch tool 191 and die
192 to make apertures 225.
[0411] Blister contents removal may be further assisted by the use
of a bespoke tool, such as illustrated in FIGS. 18A through
19D.
[0412] A bespoke `discharge` tool or key 231 is profiled for
complementary interfit with blister pack 232--aperture 234 locates
over a blister pocket 236, thereby aligning cutter blade 233 with
aperture 235 in the blister pack, such that paper backed foil 238
is penetrated.
[0413] Following removal of `discharge` tool, the pierced paper
layer 237 can be peeled off the foil layer 239, allowing blister
pocket contents 240 to be discharged upon rupture of the foil layer
239.
[0414] Referring now to the mechanical tear-off tab seal sequence
of FIGS. 20A through 20E, 21A through 21G, 22A through 22G and 23A
through 23F, a blister pack and overall cover card, or cover wrap,
are variously entrained, through single or multiple edge bonding,
to form a closed package.
[0415] Once closed and sealed, the pack can only be opened by
breaking the tab seal.
[0416] Whilst a single tab seal is depicted for an entire pack, in
principle, individual portions of the pack could be separately
closed, by respective discrete or severable cover portions and
attendant tab seals.
[0417] Moreover, the closure covers could be contrived as
interactive or interdependent--so that, say, access to covers must
follow a prescribed sequence.
[0418] This could be achieved with partial cover overlay or
interfit, or wholesale internesting or multi-layered covers or
wraps; vis wraps configured within wraps--to allow phased access
and contents discharge for consumption.
[0419] In particular, FIGS. 20A through 20E depict a blister pack
312, bonded along longitudinal edge 314 to a rectangular cover card
element 316, with closure slot 317--and along longitudinal edge 315
to card element 318 with locking tab 319.
[0420] Upon pack closure, locking tab 319 is located in slot
317.
[0421] In an alternative approach, a single card element 322, with
slot 323, is bonded along one longitudinal edge 315 of a blister
pack 312.
[0422] The card element 322 is folded over the blister pack and
held closed by a discrete locking tab 325, located through slot 323
and bonded to the underside of blister pack 312--as depicted in
FIGS. 21A through 21F.
[0423] To access the blister pack, the locking tab is severed,
along severance line 328.
[0424] For further protection, a card cover which enshrouds the
blister pack top, and is sealed along on all four sides, is
envisaged.
[0425] More specifically, a blister pack 342 is bonded on three
edges 343, 344, 345 to a triple panel element 347. Panel elements
351', 352 and finally 353 are folded to overlie the blister
pack.
[0426] Depending lip panel 355 is folded around blister pack edge
346 and bonded to its underside--thereby sealing the pack
closed.
[0427] The sealed pack is accessed by the removal of tear-off seal
tab 358.
[0428] In a simpler construction, a single element cover sleeve
363, with depending lips 366 and 367 is located over blister pack
362. Depending lips 366 and 367 are folded and bonded to the
underside of the blister back.
[0429] Again, blister pack access requires removal of tear-off seal
tab 369.
[0430] Component List
[0431] 11 blister pack
[0432] 12 mounting card
[0433] 13 perforation/severance line
[0434] 14 panel
[0435] 15 spine
[0436] 16 mounting/adhesive strip
[0437] 17 plastics sheet
[0438] 18 blister compartment
[0439] 19 (metal) foil backing layer
[0440] 20 card mounted (single) blister pack assembly
[0441] 22A mounting card
[0442] 22B mounting card
[0443] 23A severance line
[0444] 23B severance line
[0445] 24A panel
[0446] 24B panel
[0447] 25 spine
[0448] 26 adhesive strip
[0449] 28 fold line
[0450] 29 fold line
[0451] 31 mounting portion
[0452] 32 mounting portion
[0453] 33 mounting portion
[0454] 42 triangular carded blister pack assembly
[0455] 43 semi-circular carded blister pack assembly
[0456] 44 dumbbell carded blister pack assembly
[0457] 51 rectangular blister pack
[0458] 52 triangular blister pack
[0459] 53 semi-circular blister pack
[0460] 61 spine
[0461] 62 adhesive strip
[0462] 63 spine
[0463] 64 adhesive strip
[0464] 65 spine
[0465] 66 adhesive strip
[0466] 70 card mounted (multiple) blister pack assembly
[0467] 72 master binding edge
[0468] 73 protruding blister pack edge
[0469] 74 protruding blister pack edge
[0470] 75 protruding blister pack edge
[0471] 82 individual blister form
[0472] 83 individual blister form
[0473] 84 individual blister form
[0474] 160 rim
[0475] 161 paper backed foil
[0476] 162 blister pack
[0477] 163 perforation rows
[0478] 164 paper reinforced layer
[0479] 165 perforation columns
[0480] 166 aperture
[0481] 167 foil layer
[0482] 168 blister pocket
[0483] 169 patch
[0484] 170 tablet/capsule
[0485] 171 cover sheet
[0486] 172 mounting strip
[0487] 173 perforations
[0488] 174 paper foil edge
[0489] 175 edge `reveal`
[0490] 176 apertures
[0491] 177 mounting point
[0492] 179 mounting point
[0493] 182 diamond aperture
[0494] 183 star shaped aperture
[0495] 184 octagonal aperture
[0496] 186 letter profiled aperture
[0497] 187 numeral profiled aperture
[0498] 191 punch
[0499] 192 die
[0500] 194 die aperture
[0501] 196 cut-out
[0502] 209 cutter
[0503] 211 punch cutter plate
[0504] 212 pins
[0505] 214 perforations
[0506] 224 blister pack aperture
[0507] 225 paper foil layer aperture
[0508] 226 aperture
[0509] 228 edge `reveal`
[0510] 231 `discharge` tool/key
[0511] 232 blister pack
[0512] 233 cutter blade
[0513] 234 aperture
[0514] 235 aperture
[0515] 236 blister pocket
[0516] 237 paper layer
[0517] 238 paper backed foil layer
[0518] 239 foil layer
[0519] 240 blister pocket contents
[0520] 312 blister pack
[0521] 314 edge
[0522] 315 edge
[0523] 316 card element
[0524] 317 slot
[0525] 318 card element
[0526] 319 locking tab
[0527] 322 card element
[0528] 323 slot
[0529] 325 locking tab
[0530] 328 severance line
[0531] 342 blister pack
[0532] 343 edge
[0533] 344 edge
[0534] 345 edge
[0535] 346 edge
[0536] 347 triple panel element
[0537] 351 panel
[0538] 352 panel
[0539] 353 panel
[0540] 355 depending lip panel
[0541] 358 tear off seal tab
[0542] 362 blister pack
[0543] 363 single element cover sleeve
[0544] 366 depending lip
[0545] 367 depending lip
[0546] 369 tear off tab seal
* * * * *