U.S. patent application number 09/932066 was filed with the patent office on 2002-02-28 for closure for vial.
Invention is credited to Asai, Kouichi, Sudo, Morihiro.
Application Number | 20020023893 09/932066 |
Document ID | / |
Family ID | 18743731 |
Filed Date | 2002-02-28 |
United States Patent
Application |
20020023893 |
Kind Code |
A1 |
Sudo, Morihiro ; et
al. |
February 28, 2002 |
Closure for vial
Abstract
A closure for a vial includes a head portion, and a stem portion
which projects from a lower surface of the head portion, the stem
portion being inserted in an opening of a vial; wherein the stem
portion is provided with a small diameter portion and a seal
portion, in that order from the lower surface the head portion, the
diameter of the small diameter portion being smaller than the
diameter of the seal portion. The entirety of the small diameter
portion and the seal portion are substantially uniformly fitted in
the opening of the vial.
Inventors: |
Sudo, Morihiro; (Tokyo,
JP) ; Asai, Kouichi; (Tokyo, JP) |
Correspondence
Address: |
McCormick, Paulding & Huber
City Place II
185 Asylum Street
Hartford
CT
06103-3402
US
|
Family ID: |
18743731 |
Appl. No.: |
09/932066 |
Filed: |
August 17, 2001 |
Current U.S.
Class: |
215/355 |
Current CPC
Class: |
B65D 39/16 20130101;
B01L 3/50825 20130101; B65D 39/0023 20130101 |
Class at
Publication: |
215/355 |
International
Class: |
B65D 039/00 |
Foreign Application Data
Date |
Code |
Application Number |
Aug 25, 2000 |
JP |
2000-254854 (P) |
Claims
What is claimed is:
1. A closure for a vial comprising: a head portion; and a stem
portion which projects from a lower surface of the head portion,
said stem portion being inserted in an opening of a vial; wherein
said stem portion is provided with a small diameter portion and a
seal portion, in that order from said lower surface the head
portion, the diameter of said small diameter portion being smaller
than the diameter of the seal portion; and wherein the entirety of
said small diameter portion and said seal portion are substantially
uniformly fitted in the opening of the vial.
2. The closure for a vial according to claim 1, wherein the
following condition is satisfied: 0.80D.ltoreq.d.ltoreq.0.98D;
wherein d designates the diameter of the small diameter portion;
and D designates the diameter of the seal portion.
3. The closure for a vial according to claim 1, wherein the stem
portion is further provided with a leg portion connected to the
seal portion, said leg portion being provided with at least one
radial opening and a plurality of half-insertion projections formed
on the outer peripheral surface of the seal portion, the diameter
of the seal portion being smaller than the diameter of a
circumscribed circle of the half-insertion projections.
4. The closure for a vial according to claim 1, wherein the
following condition is satisfied: S/5.gtoreq.j.gtoreq.S/20; wherein
j designates the axial length of the small diameter portion; and S
designates the axial length of the seal portion.
Description
BACKGROUND OF THE INVENTION
[0001] 1. Field of the Invention
[0002] The present invention relates to a closure to close an
opening of a medical vial (container) which holds therein liquid
medicament.
[0003] 2. Description of the Related Art
[0004] In general, a closure (rubber closure) for a vial is made of
a rubber material such as butyl rubber and has a cylindrical stem
portion which can be inserted in the opening of the vial and a head
portion which has a diameter larger than that of the stem portion
and which is located on the outside of the opening of the vial. The
stem portion of a conventional closure is provided with a close
contact portion (barrel portion) having a uniform diameter which is
brought into close contact with the opening of the vial and which
is located adjacent to the head portion, or is provided on its
barrel portion with a sealing annular projection which is in close
contact with the opening of the vial. A desired position of such a
sealing annular projection is disclosed, for example, in Japanese
Unexamined Utility Model No. Sho-61-2233.
[0005] When the stem portion is fitted in the opening of the vial,
the sealing annular projection is compressed more than the
remaining portion of the barrel portion, and hence, it has been
considered that the sealing annular projection contributes to
preventing the stem portion from slipping off from the opening of
the vial. In particular, for a specific type of vial, called a CS
vial (Fuji Glass CO., Ltd.) which is provided, on the end of the
opening thereof, with an inner small diameter portion (inner
flange), the sealing annular projection engages with the small
diameter portion, so that the slip-off prevention effect can be
enhanced.
[0006] However, if the closure is used with a vial other than a CS
vial, the sealing annular projection which is compressed more than
the remaining portion sometimes produces a force in a direction
opposite to the direction of insertion to thereby disengage the
closure from the vial. Because of this phenomenon, the sealing
annular projection has also been regarded as having an opposite
effect to that of slip-off prevention.
SUMMARY OF THE INVENTION
[0007] It is an object of the present invention to eliminate the
drawbacks and resolve the problems mentioned above, by providing a
closure for a vial in which the slip-off prevention effect of the
closure from the vial can be enhanced.
[0008] It has been conceived by the inventors that by providing a
small diameter portion on the end of the stem portion adjacent to
the head portion, instead of a sealing annular projection, the
material of the portion of the stem portion of the closure that is
compressed when the stem portion is inserted in the opening of the
vial is moved into the small diameter portion. Consequently, no
force to disengage the closure from the vial opening occurs, unlike
the conventional closure having the sealing annular projection.
[0009] To achieve the object mentioned above, according to the
present invention, a closure for a vial is provided, including a
head portion, and a stem portion which projects from a lower
surface of the head portion, the stem portion being inserted in an
opening of a vial; wherein the stem portion is provided with a
small diameter portion and a seal portion, in that order from the
lower surface the head portion, the diameter of the small diameter
portion being smaller than the diameter of the seal portion. The
entirety of the small diameter portion and the seal portion are
substantially uniformly fitted in the opening of the vial.
[0010] Preferably, the following condition is satisfied:
[0011] 0.80D.ltoreq.d.ltoreq.0.98D; wherein `d` designates the
diameter of the small diameter portion, and `D` designates the
diameter of the seal portion.
[0012] Preferably, the stem portion is further provided with a leg
portion connected to the seal portion, the leg portion being
provided with at least one radial opening and a plurality of
half-insertion projections formed on the outer peripheral surface
of the seal portion, the diameter of the seal portion being smaller
than the diameter of a circumscribed circle of the half-insertion
projections.
[0013] Preferably, the following condition is satisfied:
[0014] S/5.gtoreq.j.gtoreq.S/20; wherein `j` designates the axial
length of the small diameter portion, and `S` designates the axial
length of the seal portion.
[0015] The present disclosure relates to subject matter contained
in Japanese Patent Application No.2000-254854 (filed on Aug. 25,
2000) which is expressly incorporated herein by reference in its
entirety.
BRIEF DESCRIPTION OF THE INVENTION
[0016] FIG. 1 is a partially sectioned perspective view of a
closure for a vial, according to an embodiment of the present
invention;
[0017] FIG. 2 is a front elevational view of a closure for a vial
shown in FIG. 1; and
[0018] FIG. 3 is a back view of a closure for a vial shown in FIG.
1.
DESCRIPTION OF THE PREFERRED EMBODIMENT
[0019] A closure 10 for a vial 20 according to the present
invention is composed of a head portion (top plate) 11 in the form
of a circular disc, and a cylindrical stem portion 12, which has a
diameter smaller than that of the head portion 11 and which
projects from the lower surface of the head portion 11. The stem
portion 12 is fitted in an opening (bottle neck) 21 of the vial
(container for holding liquid medicament) 20. The head portion 11
is in contact with an end face 22 of the opening 21.
[0020] The stem portion 12 is provided with a seal portion 13
adjacent to the head portion 11 and a leg portion 14 connected to
the seal portion 13. The seal portion 13 is provided on its end
adjacent to the head portion 11, with a small diameter portion 15
having a smaller diameter. The seal portion 13 has a uniform
diameter D which is slightly greater than the uniform inner
diameter x of the opening 21 of the vial 20, so that when the stem
portion is inserted in the opening 21, the seal portion 13 is
uniformly compressed to establish a press fit therebetween. There
is no sealing annular projection or other projection provided on
the closure 10, unlike a conventional closure for a vial. In an
alternative embodiment, the seal portion 13 can be provided with a
slightly tapered peripheral surface.
[0021] The diameter d and axial length (width) j of the small
diameter portion 15 are determined, taking into account a
difference in the diameter between the seal portion 13 and the
opening 21, so that when the seal portion 13 is fitted in the
opening 21 of the vial 20, the material of the portion of the seal
portion 13 that is compressed and deformed is moved into the small
diameter portion 15 so that no force is produced which would cause
the closure 10 to disengage from the vial 20. More specifically,
the diameter d of the small diameter portion 15 is preferably in
the range of d=0.80D to 0.98D (0.80D.ltoreq.d.ltoreq.0.98D)- ,
wherein D is the diameter of the seal portion 13. The axial length
j of the seal portion 15 is preferably in the range of j={{fraction
(1/5)} through {fraction (1/20)}}*S (i.e.,
S/5.gtoreq.j.gtoreq.S/20), wherein S is the axial length of the
seal portion 13. By way of example, in the closure 10 constructed
as above, the diameter of the head portion 11 is in the range of 10
mm through 30 mm and the overall length of the stem portion 12 is
in the range of 5 mm through 30 mm.
[0022] The leg portion 14 of the stem portion 12 is provided with a
radial opening 16 through which cleaning liquid can easily enter
the stem portion 12. The leg portion 14 is provided on its outer
peripheral surface with a plurality of half-insertion projections
17 (three projections in the illustrated in FIG. 2) at an equal
angular distance. When the stem portion 12 of the closure 10 is
inserted in the opening 21 of the vial 20, the projections 17 first
engage with the inner peripheral surface of the opening 21 to
provisionally hold the closure 10 while keeping the posture thereof
before the closure 10 is completely inserted in the vial 20. The
outer diameter D of the seal portion 13 is smaller than a diameter
t of a circumscribed circle to the projections 17. If the diameter
D were substantially identical to the diameter t, it would be
impossible to completely insert the closure 10 in the vial 20. If
the diametert of the circumscribed circle is larger than the outer
diameter D, the stem portion can be easily deformed due to the
presence of the opening 16, so that the closure 10 can be
half-inserted easily. The opening 16 and the projections 17 can be
appropriately increased in number.
[0023] The closure 10 is forced (press-fitted) into the opening 21
of the vial 20, after the vial 20 is filled with liquid medicament.
Upon the closure 10 being press-fitted into the vial 20, the leg
portion 14 of the stem portion 12 is elastically deformed and is
inserted in the opening 21. Consequently, the projections 17,
provided on the outer peripheral surface of the stem portion 14,
are frictionally engaged with the inner surface of the opening 21
of the vial 20 to establish a provisional holding (half-insertion
state). Thereafter, when the closure 10 is further inserted into
the opening 21, the seal portion 13 is pressed onto and brought
into uniform surface contact with the inner peripheral surface of
the opening 21 of the vial 20, so that the lower surface (under
surface) of the head portion 11 comes into contact with the end
face 22 of the opening 21. Thus, the complete insertion of the
closure 10 into the vial 20 is obtained. In this state, the
material of the portion of the seal portion 13 is partly moved into
and received in the small diameter portion 15. Hence, there is no
or little possibility that the elastic deformation of the seal
portion 13 causes the closure 10 to slip off from the vial 20.
[0024] As can be understood from the above discussion, according to
the present invention, the stem portion of the closure for a vial
is provided, on the portion thereof adjacent to the head portion,
with a seal portion that is entirely fitted in and brought into
close surface-contact with the inner surface of the opening of the
vial, and the seal portion is provided on an end thereof adjacent
to the head portion with a small diameter portion whose diameter is
smaller than the diameter of the main body of the seal portion.
According to this construction, no slipping force is applied to the
closure when the closure is fitted in the vial.
[0025] Obvious changes may be made in the specific embodiments of
the present invention described herein, such modifications being
within the spirit and scope of the invention claimed. It is
indicated that all matter contained herein is illustrative and does
not limit the scope of the present invention.
* * * * *