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Methods and compositions for targeted genetic modification through single-step multiple targeting Grant 11,326,184 - Voronina , et al. May 10, 2 | 2022-05-10 |
Cas-ready Mouse Embryonic Stem Cells And Mice And Uses Thereof App 20210392862 - Gong; Guochun ;   et al. | 2021-12-23 |
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Methods And Compositions For Assessing Crispr/cas-mediated Disruption Or Excision And Crispr/cas-induced Recombination With An Exogenous Donor Nucleic Acid In Vivo App 20210261985 - Gong; Guochun ;   et al. | 2021-08-26 |
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Methods And Compositions For Assessing Crispr/cas-induced Recombination With An Exogenous Donor Nucleic Acid In Vivo App 20190032156 - Gong; Guochun ;   et al. | 2019-01-31 |
Methods And Compositions For Assessing Crispr/cas-mediated Disruption Or Excision And Crispr/cas-induced Recombination With An Exogenous Donor Nucleic Acid In Vivo App 20190032092 - Gong; Guochun ;   et al. | 2019-01-31 |
Cas-ready Mouse Embryonic Stem Cells And Mice And Uses Thereof App 20190032155 - Gong; Guochun ;   et al. | 2019-01-31 |
Inhibitors of sodium glucose transporter 1 for constipation Grant 10,106,569 - Carson , et al. October 23, 2 | 2018-10-23 |
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Methods For Breaking Immunological Tolerance Using Multiple Guide Rnas App 20170332610 - Voronina; Vera ;   et al. | 2017-11-23 |
Inhibitors of sodium glucose cotransporter 1 Grant 9,688,710 - Carson , et al. June 27, 2 | 2017-06-27 |
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Methods And Compositions For Targeted Genetic Modification Through Single-step Multiple Targeting App 20160177339 - Voronina; Vera ;   et al. | 2016-06-23 |
Inhibitors of sodium glucose cotransporter 1 Grant 9,200,025 - Carson , et al. December 1, 2 | 2015-12-01 |
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Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same App 20090193532 - Abuin; Alejandro ;   et al. | 2009-07-30 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same App 20090149336 - Zambrowicz; Brian ;   et al. | 2009-06-11 |
Genetically Engineered and Phenotyped Mice and Stem Cell Clones for Producing the Same App 20090113564 - Abuin; Alejandro ;   et al. | 2009-04-30 |
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Methods Of Affecting Gastrointestinal Transit And Gastric Emptying, And Compounds Useful Therein App 20090029993 - Liu; Qingyun ;   et al. | 2009-01-29 |
Methods Of Treating Serotonin-mediated Diseases And Disorders App 20090005381 - Brown; Philip Manton ;   et al. | 2009-01-01 |
Novel human membrane proteins and polynucleotides encoding the same App 20080213878 - Donoho; Gregory ;   et al. | 2008-09-04 |
Genetically engineered and phenotyped mice and stem cell clones for producing the same App 20080189799 - Fan; Liangfen ;   et al. | 2008-08-07 |
Antibodies to novel lipoxygenase proteins App 20080125578 - Turner; C. Alexander ;   et al. | 2008-05-29 |
Novel human membrane proteins and polynucleotides encoding the same App 20080102520 - Abuin; Alejandro ;   et al. | 2008-05-01 |
Novel human kinases and polynucleotides encoding the same App 20080050809 - Abuin; Alejandro ;   et al. | 2008-02-28 |
Novel human secreted proteins and polynucleotides encoding the same App 20080044896 - Donoho; Gregory ;   et al. | 2008-02-21 |
Vectors for making genomic modifications Grant 7,332,338 - Zambrowicz , et al. February 19, 2 | 2008-02-19 |
Novel human proteases and polynucleotides encoding the same App 20080003673 - Abuin; Alejandro ;   et al. | 2008-01-03 |
Novel human membrane proteins and polynucleotides encoding the same App 20070298489 - Abuin; Alejandro ;   et al. | 2007-12-27 |
Polynucleotides encoding human transporter proteins Grant 7,268,222 - Harras , et al. September 11, 2 | 2007-09-11 |
Novel human polynucleotides and polypeptides encoded thereby App 20070178475 - Nehls; Michael C. ;   et al. | 2007-08-02 |
Novel lipoxygenase proteins and polynucleotides encoding the same App 20070136832 - Turner; C. Alexander JR. ;   et al. | 2007-06-14 |
Novel human uncoupling proteins and polynucleotides encoding the same App 20060293512 - Turner; C. Alexander JR. ;   et al. | 2006-12-28 |
Lipoxygenase proteins and polynucleotides encoding the same Grant 7,144,730 - Turner, Jr. , et al. December 5, 2 | 2006-12-05 |
Novel human polynucleotides and the polypeptides encoded thereby App 20060216717 - Nehls; Michael ;   et al. | 2006-09-28 |
Novel human genes and proteins encoded thereby App 20060090212 - Turner; Alexander C. JR. ;   et al. | 2006-04-27 |
Novel human enzymes and polynucleotides encoding the same App 20060063245 - Walke; D. Wade ;   et al. | 2006-03-23 |
Novel mutated mammalian cells and animals App 20060031947 - Abuin; Alejandro ;   et al. | 2006-02-09 |
Novel human GABA receptor proteins and polynucleotides encoding the same App 20060025581 - Turner; C. Alexander JR. ;   et al. | 2006-02-02 |
Human uncoupling proteins and polynucleotides encoding the same Grant 6,987,178 - Turner, Jr. , et al. January 17, 2 | 2006-01-17 |
Novel human transferase proteins and polynucleotides encoding the same App 20050287568 - Donobo, Gregory ;   et al. | 2005-12-29 |
Novel human membrane protein and polynucleotides encoding the same App 20050261488 - Walke, D. Wade ;   et al. | 2005-11-24 |
Noved human proteases and polynucleotides encoding the same App 20050222401 - Donoho, Gregory ;   et al. | 2005-10-06 |
Novel human proteases and polynucleotides encoding the same App 20050214783 - Walke, D. Wade ;   et al. | 2005-09-29 |
Novel human 7TM proteins and polynucleotides encoding the same App 20050215776 - Hu, Yi ;   et al. | 2005-09-29 |
Novel human phosphatases and polynucleotides encoding the same App 20050208571 - Walke, D. Wade ;   et al. | 2005-09-22 |
Novel Human Carboxypeptidases And Polynucleotides Encoding The Same App 20050191641 - Donoho, Gregory ;   et al. | 2005-09-01 |
Novel mutated mammalian cells and animals App 20050186677 - Friedrich, Glenn ;   et al. | 2005-08-25 |
Novel human transporter proteins and polynucleotides encoding the same App 20050181397 - Donoho, Gregory ;   et al. | 2005-08-18 |
Novel human ATPase proteins and polynucleotides encoding the same App 20050182248 - Donoho, Gregory ;   et al. | 2005-08-18 |
Novel Human Uncoupling Proteins And Polynucleotides Encoding The Same App 20050181500 - Turney, C. Alexander JR. ;   et al. | 2005-08-18 |
Human transferase proteins and polynucleotides encoding the same Grant 6,929,937 - Turner, Jr. , et al. August 16, 2 | 2005-08-16 |
Novel human proteins and polynucleotides encoding the same App 20050170384 - Turner, C. Alexander JR. ;   et al. | 2005-08-04 |
Novel human notch ligand proteins and polynucleotides encoding the same App 20050170389 - Turner, C. Alexander JR. ;   et al. | 2005-08-04 |
Novel human proteases and polynucleotides encoding the same App 20050170395 - Donoho, Gregory ;   et al. | 2005-08-04 |
Novel human kinase protein and polynucleotides encoding the same App 20050170364 - Donoho, Gregory ;   et al. | 2005-08-04 |
Novel human endothelin converting enzyme-like proteins and polynucleotides encoding the same App 20050143569 - Donoho, Gregory ;   et al. | 2005-06-30 |
Novel human transporter proteins and polynucleotides encoding the same App 20050142588 - Walke, D. Wade ;   et al. | 2005-06-30 |
Novel human thrombospondin-like proteins and polynucleotides encoding the same App 20050123955 - Turner, C. Alexander JR. ;   et al. | 2005-06-09 |
Novel human membrane proteins and polynucleotides encoding the same App 20050124802 - Turner, C. Alexander JR. ;   et al. | 2005-06-09 |
Methods and compositions for defining gene function App 20050118710 - Hansen, Gwenn ;   et al. | 2005-06-02 |
Human ATPase proteins and polynucleotides encoding the same Grant 6,900,046 - Donoho , et al. May 31, 2 | 2005-05-31 |
Novel human neurexin-like proteins and polynucleotides encoding the same App 20050096462 - Turner, C. Alexander JR. ;   et al. | 2005-05-05 |
Vectors for gene mutagenesis and gene discovery App 20050095713 - Zambrowicz, Brian ;   et al. | 2005-05-05 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same App 20050095620 - Zambrowicz, Brian ;   et al. | 2005-05-05 |
Novel human protease inhibitor-like proteins and polynucleotides encoding the same App 20050089892 - Donoho, Gregory ;   et al. | 2005-04-28 |
Novel human ion channel proteins App 20050089887 - Turner, Alexander C. JR. ;   et al. | 2005-04-28 |
Novel human phospholipases and polynucleotides encoding the same App 20050089886 - Hu, Yi ;   et al. | 2005-04-28 |
Novel human 7TM protein and polynucleotides encoding the same App 20050090000 - Turner, C. Alexander JR. ;   et al. | 2005-04-28 |
Human proteases and polynucleotides encoding the same Grant 6,881,563 - Donoho , et al. April 19, 2 | 2005-04-19 |
Novel human kinase proteins and polynucleotides encoding the same App 20050079530 - Donoho, Gregory ;   et al. | 2005-04-14 |
Novel human proteins and polynucleotides encoding the same App 20050079580 - Turner, C. Alexander JR. ;   et al. | 2005-04-14 |
Novel human secreted proteins and polynucleotides encoding the same App 20050069919 - Walke, D. Wade ;   et al. | 2005-03-31 |
Novel human 7TM proteins and polynucleotides encoding the same App 20050064466 - Walke, D. Wade ;   et al. | 2005-03-24 |
Arrayed collection of genomic clones App 20050066377 - Zambrowicz, Brian ;   et al. | 2005-03-24 |
Novel human polynucleotides and the polypeptides encoded thereby App 20050059060 - Nehls, Michael ;   et al. | 2005-03-17 |
Novel human genes and proteins encoded thereby App 20050053953 - Turner, Alex ;   et al. | 2005-03-10 |
Novel human kinase protein and polynucleotides encoding the same App 20050054844 - Mathur, Brian ;   et al. | 2005-03-10 |
Novel human proteins and polynucleotides encoding the same App 20050053969 - Donoho, Gregory ;   et al. | 2005-03-10 |
Novel human kinase proteins and polynucleotides encoding the same App 20050042626 - Donoho, Gregory ;   et al. | 2005-02-24 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same Grant 6,855,545 - Sands , et al. February 15, 2 | 2005-02-15 |
Human proteases and polynucleotides encoding the same Grant 6,852,521 - Donoho , et al. February 8, 2 | 2005-02-08 |
Novel human enzymes and polynucleotides encoding the same App 20050009087 - Donoho, Gregory ;   et al. | 2005-01-13 |
Novel human polynucleotides and the polypeptides encoded thereby App 20050003444 - Nehls, Michael ;   et al. | 2005-01-06 |
Novel human polynucleotides and the polypeptides encoded thereby App 20050003443 - Nehls, Michael ;   et al. | 2005-01-06 |
Human endothelin converting enzyme-like proteins and polynucleotides encoding the same Grant 6,835,564 - Donoho , et al. December 28, 2 | 2004-12-28 |
Vectors for gene mutagenesis and gene discovery App 20040259253 - Zambrowicz, Brian ;   et al. | 2004-12-23 |
Novel human transferase proteins and polynucleotides encoding the same App 20040214202 - Walke, D. Wade ;   et al. | 2004-10-28 |
Vectors for gene mutagenesis and gene discovery Grant 6,808,921 - Zambrowicz , et al. October 26, 2 | 2004-10-26 |
Human kinase proteins and polynucleotides encoding the same Grant 6,806,073 - Donoho , et al. October 19, 2 | 2004-10-19 |
Human LDL receptor encoding polynucleotides Grant 6,806,083 - Turner, Jr. , et al. October 19, 2 | 2004-10-19 |
Novel human proteases and polynucleotides encoding the same App 20040203059 - Donoho, Gregory ;   et al. | 2004-10-14 |
Novel human calcium dependent proteases, polynucleotides encoding the same, and uses thereof App 20040198968 - Donoho, Gregory ;   et al. | 2004-10-07 |
Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby App 20040168209 - Abuin, Alejandro ;   et al. | 2004-08-26 |
Human carboxypeptidases and polynucleotides encoding the same Grant 6,780,640 - Donoho , et al. August 24, 2 | 2004-08-24 |
Human proteases and polynucleotides encoding the same Grant 6,777,221 - Donoho , et al. August 17, 2 | 2004-08-17 |
Vectors for gene mutagenesis and gene discovery Grant 6,776,988 - Zambrowicz , et al. August 17, 2 | 2004-08-17 |
Novel human ion channel protein and polynucleotides encoding the same App 20040157259 - Hu, Yi ;   et al. | 2004-08-12 |
Human ion channel protein and polynucleotides encoding the same Grant 6,767,736 - Hu , et al. July 27, 2 | 2004-07-27 |
Novel human thrombospondin repeat proteins and polynucleotides encoding the same App 20040143113 - Donoho, Gregory ;   et al. | 2004-07-22 |
Novel human proteases and polynucleotides encoding the same App 20040137502 - Donoho, Gregory ;   et al. | 2004-07-15 |
Human kinase protein and polynucleotides encoding the same Grant 6,746,861 - Donoho , et al. June 8, 2 | 2004-06-08 |
Human proteins and polynucleotides encoding the same Grant 6,743,907 - Donoho , et al. June 1, 2 | 2004-06-01 |
Human proteases and polynucleotides encoding the same Grant 6,743,621 - Donoho , et al. June 1, 2 | 2004-06-01 |
Novel human membrane proteins App 20040077078 - Wattler, Frank ;   et al. | 2004-04-22 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same App 20040072243 - Sands, Arthur ;   et al. | 2004-04-15 |
Human kinase protein and polynucleotides encoding the same Grant 6,720,173 - Mathur , et al. April 13, 2 | 2004-04-13 |
Human thrombospondin repeat proteins and polynucleotides encoding the same Grant 6,720,412 - Donoho , et al. April 13, 2 | 2004-04-13 |
Human kinase proteins and polynucleotides encoding the same Grant 6,716,616 - Donoho , et al. April 6, 2 | 2004-04-06 |
Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof Grant 6,716,614 - Donoho , et al. April 6, 2 | 2004-04-06 |
Human transferase proteins and polynucleotides encoding the same Grant 6,692,947 - Walke , et al. February 17, 2 | 2004-02-17 |
Novel human kinase proteins and polynucleotides encoding the same App 20040014112 - Donoho, Gregory ;   et al. | 2004-01-22 |
Novel human GABA receptor proteins and polynucleotides encoding the same App 20030229217 - Turner, C. Alexander JR. ;   et al. | 2003-12-11 |
Novel human proteases and polynucleotides encoding the same App 20030225258 - Donoho, Gregory ;   et al. | 2003-12-04 |
Novel human 7TM proteins and polynucleotides encoding the same App 20030225246 - Hu, Yi ;   et al. | 2003-12-04 |
Novel human transporter proteins and polynucleotides encoding the same App 20030220491 - Walke, D. Wade ;   et al. | 2003-11-27 |
Human proteases and polynucleotides encoding the same Grant 6,649,399 - Donoho , et al. November 18, 2 | 2003-11-18 |
Novel lipoxygenase proteins and polynucleotides encoding the same App 20030172391 - Turner, C. Alexander JR. ;   et al. | 2003-09-11 |
Novel human transferase proteins and polynucleotides encoding the same App 20030166839 - Walke, D. Wade ;   et al. | 2003-09-04 |
Novel human secreted proteins and polynucleotides encoding the same App 20030166883 - Walke, D. Wade ;   et al. | 2003-09-04 |
Novel human transporter proteins App 20030162713 - Turner, Alex ;   et al. | 2003-08-28 |
Human kinase proteins and polynucleotides encoding the same Grant 6,602,698 - Donoho , et al. August 5, 2 | 2003-08-05 |
Novel human transferase proteins and polynucleotides encoding the same App 20030144497 - Donoho, Gregory ;   et al. | 2003-07-31 |
Novel human 7TM protein and polynucleotides encoding the same App 20030130495 - Turner, C. Alexander JR. ;   et al. | 2003-07-10 |
Lipoxygenase proteins and polynucleotides encoding the same Grant 6,582,957 - Turner, Jr. , et al. June 24, 2 | 2003-06-24 |
Novel human LDL receptor family proteins and polynucleotides encoding the same App 20030078383 - Turner, C. Alexander JR. ;   et al. | 2003-04-24 |
Novel human kinase proteins and polynucleotides encoding the same App 20030064495 - Donoho, Gregory ;   et al. | 2003-04-03 |
Novel human enzymes and polynucleotides encoding the same App 20030054513 - Donoho, Gregory ;   et al. | 2003-03-20 |
Human Transporter Proteins And Polynucleotides Encoding The Same App 20030039962 - Hu, Yi ;   et al. | 2003-02-27 |
Novel human phosphatases and polynucleotides encoding the same App 20030023064 - Walke, D. Wade ;   et al. | 2003-01-30 |
Novel human proteases and polynucleotides encoding the same App 20030023062 - Donoho, Gregory ;   et al. | 2003-01-30 |
Novel human ATPase proteins and polynucleotides encoding the same App 20030023065 - Donoho, Gregory ;   et al. | 2003-01-30 |
Novel human proteases and polynucleotides encoding the same App 20030009021 - Donoho, Gregory ;   et al. | 2003-01-09 |
Novel human GABA receptor proteins and polynucleotides encoding the same App 20020183507 - Turner, C. Alexander JR. ;   et al. | 2002-12-05 |
Vectors for gene mutagenesis and gene discovery App 20020182724 - Zambrowicz, Brian ;   et al. | 2002-12-05 |
Novel human carboxypeptidases and polynucleotides encoding the same App 20020173641 - Donoho, Gregory ;   et al. | 2002-11-21 |
Novel human proteases and polynucleotides encoding the same App 20020165376 - Walke, D. Wade ;   et al. | 2002-11-07 |
Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby App 20020161207 - Friedrich, Glenn ;   et al. | 2002-10-31 |
Novel human 7TM proteins and polynucleotides encoding the same App 20020128462 - Hu, Yi ;   et al. | 2002-09-12 |
Novel human proteases and polynocleotides encoding the same App 20020120113 - Donoho, Gregory ;   et al. | 2002-08-29 |
Novel human membrane proteins and polynucleotides encoding the same App 20020115837 - Turner, C. Alexander JR. ;   et al. | 2002-08-22 |
Novel human bcl-x-like proteins and polynucleotides encoding the same App 20020110893 - Donoho, Gregory ;   et al. | 2002-08-15 |
Novel human polynucleotides and polypeptides encoded thereby App 20020110809 - Nehls, Michael C. ;   et al. | 2002-08-15 |
Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby App 20020102543 - Friedrich, Glenn ;   et al. | 2002-08-01 |
Novel human membrane proteins and polynucleotides encoding the same App 20020103359 - Donoho, Gregory ;   et al. | 2002-08-01 |
Novel human thrombospondin repeat proteins and polynucleotides encoding the same App 20020099027 - Donoho, Gregory ;   et al. | 2002-07-25 |
Novel human transferase proteins and polynucleotides encoding the same App 20020098486 - Donoho, Gregory ;   et al. | 2002-07-25 |
Novel human polynucleotides and polypeptides encoded thereby App 20020095031 - Nehls, Michael C. ;   et al. | 2002-07-18 |
Novel human transporter proteins and polynucleotides encoding the same App 20020082405 - Donoho, Gregory ;   et al. | 2002-06-27 |
Novel human phospholipases and polynucleotides encoding the same App 20020081595 - Hu, Yi ;   et al. | 2002-06-27 |
Novel murine polynucleotide sequences and mutant cells and mutant animals defined thereby App 20020081668 - Friedrich, Glenn ;   et al. | 2002-06-27 |
Novel human neurexin-like proteins and polynucleotides encoding the same App 20020077464 - Turner, C. Alexander JR. ;   et al. | 2002-06-20 |
Human uncoupling proteins and polynucleotides encoding the same Grant 6,403,784 - Turner, Jr. , et al. June 11, 2 | 2002-06-11 |
Noel human thrombospondin-like proteins and polynucleotides encoding the same App 20020049312 - Turner, C. Alexander JR. ;   et al. | 2002-04-25 |
Novel human 7TM proteins and polynucleotides encoding the same App 20020045740 - Walke, D. Wade ;   et al. | 2002-04-18 |
Novel human ion channel protein and polynucleotides encoding the same App 20020042505 - Hu, Yi ;   et al. | 2002-04-11 |
Novel human kinases and polynucleotides encoding the same App 20020038011 - Walke, D. Wade ;   et al. | 2002-03-28 |
Novel human kinase protein and polynucleotides encoding the same App 20020038009 - Donoho, Gregory ;   et al. | 2002-03-28 |
Novel human regulatory protein and polynucleotides encoding the same App 20020038012 - Donoho, Gregory ;   et al. | 2002-03-28 |
Novel human transporter protein and polynucleotides encoding the same App 20020034799 - Donoho, Gregory ;   et al. | 2002-03-21 |
Arrayed collection of genomic clones App 20020031829 - Zambrowicz, Brian ;   et al. | 2002-03-14 |
Novel human proteases and polynucleotides encoding the same App 20020004591 - Donoho, Gregory ;   et al. | 2002-01-10 |
Novel human membrane protein and polynucleotides encoding the same App 20010034438 - Walke, D. Wade ;   et al. | 2001-10-25 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same Grant 6,207,371 - Zambrowicz , et al. March 27, 2 | 2001-03-27 |
Targeted gene discovery Grant 6,139,833 - Burgess , et al. October 31, 2 | 2000-10-31 |
Indexed library of cells containing genomic modifications and methods of making and utilizing the same Grant 6,136,566 - Sands , et al. October 24, 2 | 2000-10-24 |
Vectors for gene trapping and gene activation Grant 6,080,576 - Zambrowicz , et al. June 27, 2 | 2000-06-27 |