Patent | Date |
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Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor Grant 10,517,866 - Laberge , et al. Dec | 2019-12-31 |
Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye Grant 10,478,432 - Laberge , et al. Nov | 2019-11-19 |
Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss Grant 10,478,433 - Laberge , et al. Nov | 2019-11-19 |
Therapy For Removing Senescent Cells And Treating Senescence-associated Disease Using An Mdm2 Inhibitor App 20190343832 - Laberge; Remi-Martin ;   et al. | 2019-11-14 |
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinase Grant 10,413,542 - Laberge , et al. Sept | 2019-09-17 |
Passive Vaccine For Elimination Of Senescent Cells App 20190201510 - Vasserot; Alain Philippe ;   et al. | 2019-07-04 |
Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells Grant 10,328,073 - Laberge , et al. | 2019-06-25 |
Immunogenic compositions for inducing an immune response for elimination of senescent cells Grant 10,279,018 - Vasserot , et al. | 2019-05-07 |
Use Of Sulfonamide Inhibitors Of Bcl-2 And Bcl-xl To Treat Ophthalmic Disease By Selectively Removing Senescent Cells App 20190022090 - Laberge; Remi-Martin ;   et al. | 2019-01-24 |
Methods and Compositions for Killing Senescent Cells and for Treating Senescence-Associated Diseases and Disorders App 20180256568 - Laberge; Remi-Martin ;   et al. | 2018-09-13 |
Removing Senescent Cells From A Mixed Cell Population Or Tissue Using A Phosphoinositide 3-kinase (pi3k) Inhibitor App 20180250296 - Laberge; Remi-Martin ;   et al. | 2018-09-06 |
Treatment of Ophthalmic Conditions by Selectively Removing Senescent Cells from the Eye App 20180235957 - Laberge; Remi-Martin ;   et al. | 2018-08-23 |
Compositions And Methods For Treating Senescence-associated Diseases And Disorders App 20180193458 - Lopez-Dominguez; Jose Alberto ;   et al. | 2018-07-12 |
Treatment of ophthalmic conditions by selectively removing senescent cells from the eye Grant 10,010,546 - Laberge , et al. July 3, 2 | 2018-07-03 |
Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2 Grant 9,993,472 - Laberge , et al. June 12, 2 | 2018-06-12 |
Treatment Of Ophthalmic Conditions By Selectively Removing Senescent Cells From The Eye App 20180117038 - Laberge; Remi-Martin ;   et al. | 2018-05-03 |
Aminoacyl tRNA synthetases for modulating inflammation Grant 9,943,577 - Watkins , et al. April 17, 2 | 2018-04-17 |
Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline Grant 9,855,266 - Laberge , et al. January 2, 2 | 2018-01-02 |
Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells Grant 9,849,128 - Laberge , et al. December 26, 2 | 2017-12-26 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170348307 - Laberge; Remi-Martin ;   et al. | 2017-12-07 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170224680 - Laberge; Remi-Martin ;   et al. | 2017-08-10 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170209435 - Laberge; Remi-Martin ;   et al. | 2017-07-27 |
Aminoacyl Trna Synthetases For Modulating Inflammation App 20170202933 - Watkins; Jeffry Dean ;   et al. | 2017-07-20 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170198253 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170196857 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20170196858 - Laberge; Remi-Martin ;   et al. | 2017-07-13 |
Aminoacyl tRNA synthetases for modulating inflammation Grant 9,540,628 - Watkins , et al. January 10, 2 | 2017-01-10 |
Methods And Compositions For Killing Senescent Cells And For Treating Senescence-associated Diseases And Disorders App 20160339019 - Laberge; Remi-Martin ;   et al. | 2016-11-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tryptophanyl-tRNA synthetases Grant 9,399,770 - Greene , et al. July 26, 2 | 2016-07-26 |
Amino acyl tRNA synthetases for modulating inflammation Grant 9,328,340 - Watkins , et al. May 3, 2 | 2016-05-03 |
Immunogenic Compositions For Inducing An Immune Response For Elimination Of Senescent Cells App 20160038576 - Vasserot; Alain Philippe ;   et al. | 2016-02-11 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Tyrosyl-trna Synthetases App 20150353914 - GREENE; Leslie Ann ;   et al. | 2015-12-10 |
Aminoacyl tRNA synthetases for modulating inflammation Grant 9,127,268 - Watkins , et al. September 8, 2 | 2015-09-08 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases Grant 9,068,177 - Greene , et al. June 30, 2 | 2015-06-30 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases Grant 9,062,301 - Greene , et al. June 23, 2 | 2015-06-23 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex Grant 9,062,302 - Greene , et al. June 23, 2 | 2015-06-23 |
Aminoacyl Trna Synthetases For Modulating Inflammation App 20150140072 - Watkins; Jeffry Dean ;   et al. | 2015-05-21 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases Grant 9,034,321 - Greene , et al. May 19, 2 | 2015-05-19 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases Grant 9,034,598 - Greene , et al. May 19, 2 | 2015-05-19 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Valyl-tRNA synthetases Grant 9,034,320 - Greene , et al. May 19, 2 | 2015-05-19 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases Grant 9,029,506 - Greene , et al. May 12, 2 | 2015-05-12 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases Grant 8,999,321 - Greene , et al. April 7, 2 | 2015-04-07 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases Grant 8,993,723 - Greene , et al. March 31, 2 | 2015-03-31 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl-tRNA synthetases Grant 8,986,681 - Greene , et al. March 24, 2 | 2015-03-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases Grant 8,986,680 - Greene , et al. March 24, 2 | 2015-03-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase Grant 8,980,253 - Greene , et al. March 17, 2 | 2015-03-17 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-tRNA synthetases Grant 8,981,045 - Greene , et al. March 17, 2 | 2015-03-17 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-tRNA synthetases Grant 8,969,301 - Greene , et al. March 3, 2 | 2015-03-03 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases Grant 8,961,960 - Chiang , et al. February 24, 2 | 2015-02-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Lysyl-tRNA synthetases Grant 8,962,560 - Greene , et al. February 24, 2 | 2015-02-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases Grant 8,961,961 - Greene , et al. February 24, 2 | 2015-02-24 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases Grant 8,945,541 - Greene , et al. February 3, 2 | 2015-02-03 |
Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of seryl-tRNA synthetases Grant 8,946,157 - Greene , et al. February 3, 2 | 2015-02-03 |
Anti-IL-6 antibodies Grant 8,623,362 - Chen , et al. January 7, 2 | 2014-01-07 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Tryptophanyl-trna Synthetases App 20130330312 - Greene; Leslie Ann ;   et al. | 2013-12-12 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Seryl-trna Synthetases App 20130315887 - Greene; Leslie Ann ;   et al. | 2013-11-28 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Alanyl-trna Synthetases App 20130287755 - Greene; Leslie Ann ;   et al. | 2013-10-31 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Aspartyl-trna Synthetases App 20130280230 - Greene; Leslie Ann ;   et al. | 2013-10-24 |
Amino Acyl Trna Synthetases For Modulating Inflammation App 20130273045 - Watkins; Jeffry Dean ;   et al. | 2013-10-17 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Lysyl-trna Synthetases App 20130243745 - Greene; Leslie Ann ;   et al. | 2013-09-19 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Methionyl-trna Synthetases App 20130236440 - Greene; Leslie Ann ;   et al. | 2013-09-12 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Glutaminyl-trna Synthetases App 20130230505 - Greene; Leslie Ann ;   et al. | 2013-09-05 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of P38 Multi-trna Synthetase Complex App 20130230507 - Greene; Leslie Ann ;   et al. | 2013-09-05 |
INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF TYROSYL-tRNA SYNTHETASES App 20130230508 - Greene; Leslie Ann ;   et al. | 2013-09-05 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Glycyl-trna Synthetases App 20130224174 - Greene; Leslie Ann ;   et al. | 2013-08-29 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Glutamyl-prolyl-trna Synthetases App 20130224173 - Greene; Leslie Ann ;   et al. | 2013-08-29 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Asparaginyl Trna Synthetases App 20130209472 - Greene; Leslie Ann ;   et al. | 2013-08-15 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Leucyl-trna Synthetases App 20130209434 - Greene; Leslie Ann ;   et al. | 2013-08-15 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Valyl-trna Synthetases App 20130202574 - Greene; Leslie Ann ;   et al. | 2013-08-08 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Histidyl-trna Synthetases App 20130202576 - Greene; Leslie Ann ;   et al. | 2013-08-08 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Phenylalanyl-beta-trna Synthetases App 20130202575 - Greene; Leslie Ann ;   et al. | 2013-08-08 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Phenylalanyl-alpha-trna Synthetases App 20130195832 - Greene; Leslie Ann ;   et al. | 2013-08-01 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related Protein Fragments Of Arginyl-trna Synthetases App 20130142774 - Greene; Leslie Ann ;   et al. | 2013-06-06 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Isoleucyl Trna Synthetases App 20130129703 - Chiang; Kyle P. ;   et al. | 2013-05-23 |
INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF CYSTEINYL-tRNA SYNTHETASE App 20130129705 - Greene; Leslie Ann ;   et al. | 2013-05-23 |
Innovative Discovery Of Therapeutic, Diagnostic, And Antibody Compositions Related To Protein Fragments Of Threonyl-trna Synthetases App 20130129704 - Greene; Leslie Ann ;   et al. | 2013-05-23 |
Amino Acyl Trna Synthetases For Modulating Inflammation App 20130108630 - Watkins; Jeffry Dean ;   et al. | 2013-05-02 |
Anti-IL-6 Antibodies, Compositions, Methods and Uses App 20130017208 - Chen; Yan ;   et al. | 2013-01-17 |
Anti-IL-6 antibodies, compositions, methods and uses Grant RE43,672 - Chan , et al. September 18, 2 | 2012-09-18 |
Anti-IL-6 antibodies, compositions, methods and uses Grant 8,226,611 - Chen , et al. July 24, 2 | 2012-07-24 |
Anti-IL-6 Antibodies, Compositions, Methods and Uses App 20120045453 - CHEN; YAN ;   et al. | 2012-02-23 |
Methods of treating conditions using anti-IL-6 antibodies Grant 8,067,003 - Chen , et al. November 29, 2 | 2011-11-29 |
Methods of Diagnosing and Treating Conditions Using Anti-IL-6 Antibodies App 20110081355 - CHEN; YAN ;   et al. | 2011-04-07 |
Anti-IL-23 antibodies Grant 7,872,102 - Beidler , et al. January 18, 2 | 2011-01-18 |
Anti-IL-6 antibody nucleic acid molecules and methods Grant 7,833,755 - Chen , et al. November 16, 2 | 2010-11-16 |
Anti-egfr Antibodies App 20100166755 - BEIDLER; Catherine Brautigam ;   et al. | 2010-07-01 |
Anti-EGFR antibodies Grant 7,723,484 - Beidler , et al. May 25, 2 | 2010-05-25 |
Humanized anti-IL-1 beta antibodies Grant 7,714,120 - Dickinson , et al. May 11, 2 | 2010-05-11 |
Thrombopoietic Activity Of Tyrosyl-trna Synthetase Polypeptides App 20100092434 - Belani; Rajesh ;   et al. | 2010-04-15 |
Anti-IL-23 Antibodies App 20090240036 - Beidler; Catherine Brautigam ;   et al. | 2009-09-24 |
Anti-IL-6 Antibody Nucleic Acid Molecules and Methods App 20090239258 - Chen; Yan ;   et al. | 2009-09-24 |
Human Il-1 Beta Antagonists App 20090209004 - Dickinson; Craig Duane ;   et al. | 2009-08-20 |
Methods Of Optimizing Antibody Variable Region Binding Affinity App 20090202986 - Huse; William D. ;   et al. | 2009-08-13 |
Anti-il-6 antibodies, compositions, methods and uses Grant 7,560,112 - Chen , et al. July 14, 2 | 2009-07-14 |
Humanized anti-IL-1.beta. antibodies Grant 7,541,033 - Dickinson , et al. June 2, 2 | 2009-06-02 |
Humanized anti-ghrelin antibodies Grant 7,479,271 - Marquis , et al. January 20, 2 | 2009-01-20 |
Anti-Egfr Antibodies App 20080274114 - Beidler; Catherine Brautigam ;   et al. | 2008-11-06 |
Telomerase Promoter Sequences for Screening Telomerase Modulators App 20080220438 - Morin; Gregg B. ;   et al. | 2008-09-11 |
Humanized Anti-Ghrelin Antibodies App 20080118498 - Marquis; David Matthew ;   et al. | 2008-05-22 |
Anti-IL-6 antibodies, compositions, methods and uses App 20060257407 - Chen; Yan ;   et al. | 2006-11-16 |
Human il-1 beta antagonists App 20060140932 - Dickinson; Craig Duane ;   et al. | 2006-06-29 |