name:-0.25073409080505
name:-0.22405004501343
name:-0.024838924407959
Sangamo BioSciences, Inc. Patent Filings

Sangamo BioSciences, Inc.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Sangamo BioSciences, Inc..The latest application filed is for "genome editing in rats using zinc-finger nucleases".

Company Profile
18.200.200
  • Sangamo BioSciences, Inc. - Richmond CA US
  • SANGAMO BIOSCIENCES, INC.; - US
*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.
Trademarks
Patent Activity
PatentDate
Targeted disruption of the T cell receptor
Grant 11,352,631 - Lee , et al. June 7, 2
2022-06-07
Methods and compositions for treating Huntington's Disease
Grant 11,110,154 - Froelich , et al. September 7, 2
2021-09-07
Isolated human cell with an inactivated glucocorticoid receptor gene
Grant 10,907,175 - Reik , et al. February 2, 2
2021-02-02
Methods and compositions for enhancing targeted transgene integration
Grant 10,889,834 - Cost , et al. January 12, 2
2021-01-12
Methods and compositions for delivery of biologics
Grant 10,883,119 - Cost January 5, 2
2021-01-05
Compositions for linking DNA-binding domains and cleavage domains
Grant 10,724,020 - Miller , et al.
2020-07-28
Methods and compositions for increased transgene expression
Grant 10,717,993 - Holmes , et al.
2020-07-21
Zinc finger nuclease-mediated homologous recombination
Grant 10,669,551 - Cai , et al.
2020-06-02
Optimized non-canonical zinc finger proteins
Grant 10,662,434 - Cai , et al.
2020-05-26
Method of treating mucopolysaccharidosis type I or II
Grant 10,648,001 - Rebar
2020-05-12
Methods and compositions for engineering immunity
Grant 10,639,383 - Holmes , et al.
2020-05-05
Delivery methods and compositions for nuclease-mediated genome engineering
Grant 10,604,771 - Cannon , et al.
2020-03-31
Methods and compositions for integration of an exogenous sequence within the genome of plants
Grant 10,501,748 - Ainley , et al. Dec
2019-12-10
HTT repressors and uses thereof
Grant 10,435,441 - Froelich , et al. O
2019-10-08
Method of treating factor IX deficiency using nuclease-mediated targeted integration
Grant 10,370,680 - Holmes , et al.
2019-08-06
Targeted modification of malate dehydrogenase
Grant 10,358,684 - Shukla , et al.
2019-07-23
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
Grant 10,344,289 - Gupta , et al. July 9, 2
2019-07-09
Genome Editing In Rats Using Zinc-finger Nucleases
App 20190062789 - Cui; Xiaoxia ;   et al.
2019-02-28
Methods and compositions for increasing transgene activity
Grant 10,179,918 - Cost Ja
2019-01-15
Methods and compositions for nuclease-mediated targeted integration of transgenes
Grant 10,174,331 - Cost , et al. J
2019-01-08
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
Grant 10,155,011 - Bonini , et al. Dec
2018-12-18
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
Grant 10,117,899 - Genovese , et al. November 6, 2
2018-11-06
Methods and compositions for genome engineering
Grant 10,081,661 - Miller , et al. September 25, 2
2018-09-25
Methods and compositions for treatment of a beta thalessemia
Grant 10,072,066 - Liu , et al. September 11, 2
2018-09-11
Methods and compositions for modification of a HLA locus
Grant 10,072,062 - Collingwood , et al. September 11, 2
2018-09-11
Methods and compositions for modulating PD1
Grant 10,046,028 - Gregory , et al. August 14, 2
2018-08-14
Compositions for linking DNA-binding domains and cleavage domains
Grant 9,982,245 - Miller May 29, 2
2018-05-29
Methods and compositions for nuclease design
Grant 9,970,001 - Miller May 15, 2
2018-05-15
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,970,028 - Cost , et al. May 15, 2
2018-05-15
Methods and compositions for treatment of a genetic condition
Grant 9,963,715 - Cost , et al. May 8, 2
2018-05-08
FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
Grant 9,963,711 - Cogan , et al. May 8, 2
2018-05-08
Delivery methods and compositions for nuclease-mediated genome engineering
Grant 9,957,526 - Holmes , et al. May 1, 2
2018-05-01
Nuclease-mediated regulation of gene expression
Grant 9,957,501 - Reik , et al. May 1, 2
2018-05-01
Method of treating lysosomal storage diseases
Grant 9,956,247 - Rebar May 1, 2
2018-05-01
Methods and compositions for treating trinucleotide repeat disorders
Grant 9,943,565 - Gregory , et al. April 17, 2
2018-04-17
Targeted disruption of T cell receptor genes using talens
Grant 9,937,207 - Gregory , et al. April 10, 2
2018-04-10
Targeted integration into the PPP1R12C locus
Grant 9,914,940 - DeKelver , et al. March 13, 2
2018-03-13
FAD3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
Grant 9,914,930 - Cogan , et al. March 13, 2
2018-03-13
Methods and compositions for treatment of a genetic condition
Grant 9,902,974 - Conway , et al. February 27, 2
2018-02-27
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
Grant 9,890,395 - Collingwood , et al. February 13, 2
2018-02-13
Method of treating lysosomal storage diseases using nucleases and a transgene
Grant 9,877,988 - Rebar January 30, 2
2018-01-30
Methods and compositions for treatment of a genetic condition
Grant 9,873,894 - Conway , et al. January 23, 2
2018-01-23
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
Grant 9,816,074 - Conway , et al. November 14, 2
2017-11-14
DNA-binding proteins and uses thereof
Grant 9,783,827 - Gregory , et al. October 10, 2
2017-10-10
Methods and compositions for targeted cleavage and recombination
Grant 9,782,437 - Holmes , et al. October 10, 2
2017-10-10
Methods and compositions for regulation of transgene expression
Grant 9,777,281 - Rebar October 3, 2
2017-10-03
Methods and compositions for treating hemophilia
Grant 9,771,403 - Miller , et al. September 26, 2
2017-09-26
Engineered cleavage half-domains for generating nuclease-mediated genomic modifications in a cell
Grant 9,765,361 - Doyon , et al. September 19, 2
2017-09-19
Linear donor constructs for targeted integration
Grant 9,765,360 - DeKelver , et al. September 19, 2
2017-09-19
Gene editing for HIV gene therapy
Grant 9,757,420 - Gregory , et al. September 12, 2
2017-09-12
Methods and compostions for targeted genomic deletion
Grant 9,752,140 - Urnov , et al. September 5, 2
2017-09-05
Compositions For Linking Dna-binding Domains And Cleavage Domains
App 20170218349 - Miller; Jeffrey C. ;   et al.
2017-08-03
Modification of CXCR4 using engineered zinc finger proteins
Grant 9,717,759 - Holmes , et al. August 1, 2
2017-08-01
Targeted Disruption Of The T Cell Receptor
App 20170211075 - Lee; Gary K. ;   et al.
2017-07-27
Methods And Compositions For Engineering Immunity
App 20170196992 - Holmes; Michael C. ;   et al.
2017-07-13
Targeted deletion of cellular DNA sequences
Grant 9,695,442 - Guschin , et al. July 4, 2
2017-07-04
Targeted Disruption Of The Mhc Cell Receptor
App 20170173080 - Lee; Gary K. ;   et al.
2017-06-22
Methods And Compositions For Increasing Rna Activity In A Cell
App 20170137845 - Tan; Siyuan ;   et al.
2017-05-18
Methods and compositions for treatment of a genetic condition
Grant 9,650,648 - Cost , et al. May 16, 2
2017-05-16
Liver-specific Constructs, Factor Viii Expression Cassettes And Methods Of Use Thereof
App 20170119906 - Riley; Brigit E.
2017-05-04
Engineered zinc finger proteins targeting plant genes involved in fatty acid biosynthesis
Grant 9,631,201 - DeKelver , et al. April 25, 2
2017-04-25
Methods and compositions for treating hemophilia B
Grant 9,629,930 - Gregory , et al. April 25, 2
2017-04-25
Methods and compositions for gene correction
Grant 9,631,187 - Jaenisch , et al. April 25, 2
2017-04-25
Methods and compositions for targeted single-stranded cleavage and targeted integration
Grant 9,631,186 - Wang April 25, 2
2017-04-25
Modulation of stem cells using zinc finger proteins
Grant 9,624,509 - Wolffe , et al. April 18, 2
2017-04-18
Methods and compositions for regulation of zinc finger protein expression
Grant 9,624,498 - Froelich , et al. April 18, 2
2017-04-18
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
Grant 9,616,090 - Conway , et al. April 11, 2
2017-04-11
Htt Repressors And Uses Thereof
App 20170096460 - Froelich; Steven ;   et al.
2017-04-06
Targeted Modification Of Malate Dehydrogenase
App 20170088825 - Shukla; Vipula ;   et al.
2017-03-30
T cell modifying compounds and uses thereof
Grant 9,597,357 - Gregory , et al. March 21, 2
2017-03-21
Methods and compositions for prevention or treatment of a disease
Grant 9,574,211 - Gregory , et al. February 21, 2
2017-02-21
Fad2 Performance Loci And Corresponding Target Site Specific Binding Proteins Capable Of Inducing Targeted Breaks
App 20170044559 - Ainley; W. Michael ;   et al.
2017-02-16
Genome editing of a Rosa locus using nucleases
Grant 9,567,573 - Gregory , et al. February 14, 2
2017-02-14
Methods and compositions for inhibiting viral entry into cells
Grant 9,566,352 - Holmes , et al. February 14, 2
2017-02-14
Compositions for linking DNA-binding domains and cleavage domains
Grant 9,567,609 - Paschon , et al. February 14, 2
2017-02-14
Methods And Compositions For Treating Huntington's Disease
App 20170035839 - Miller; Jeffrey C. ;   et al.
2017-02-09
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering
App 20170016027 - Lee; Gary K. ;   et al.
2017-01-19
Novel Dna-binding Proteins And Uses Thereof
App 20170016030 - Gregory; Philip D. ;   et al.
2017-01-19
Nuclease-mediated Regulation Of Gene Expression
App 20160369262 - Reik; Andreas ;   et al.
2016-12-22
Targeted modification of malate dehydrogenase
Grant 9,523,098 - Shukla , et al. December 20, 2
2016-12-20
Engineered transcription activator like effector (TALE) proteins
Grant 9,522,936 - Miller , et al. December 20, 2
2016-12-20
Rapid in vivo identification of biologically active nucleases
Grant 9,506,120 - Doyon , et al. November 29, 2
2016-11-29
Methods and compositions for treating Huntington's disease
Grant 9,499,597 - Miller , et al. November 22, 2
2016-11-22
Regulation of endogenous gene expression in cells using zinc finger proteins
Grant 9,491,934 - Cox, III , et al. November 15, 2
2016-11-15
FAD2 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks
Grant 9,493,779 - Ainley , et al. November 15, 2
2016-11-15
DNA-binding proteins and uses thereof
Grant 9,493,750 - Gregory , et al. November 15, 2
2016-11-15
Methods And Compositions For Increasing Transgene Activity
App 20160326548 - Cost; Gregory J.
2016-11-10
Zinc Finger Nuclease-mediated Homologous Recombination
App 20160326537 - Cai; Qihua C. ;   et al.
2016-11-10
Methods And Compositions For Gene Inactivation
App 20160326505 - Ando; Dale ;   et al.
2016-11-10
Compositions For Linking Dna-binding Domains And Cleavage Domains
App 20160312197 - Miller; Jeffrey C.
2016-10-27
Methods And Compositions For Treating Huntington's Disease
App 20160296605 - Zhang; H. Steve
2016-10-13
Targeted Integration Into The Ppp1r12c Locus
App 20160289699 - DeKelver; Russell ;   et al.
2016-10-06
Modified DNA-binding proteins and uses thereof
Grant 9,458,205 - Gregory , et al. October 4, 2
2016-10-04
Engineered Cleavage Half-domains
App 20160265000 - Doyon; Yannick ;   et al.
2016-09-15
Methods and compositions for gene inactivation
Grant 9,434,776 - Ando , et al. September 6, 2
2016-09-06
Zinc finger nuclease-mediated homologous recombination
Grant 9,428,756 - Cai , et al. August 30, 2
2016-08-30
Linear Donor Constructs For Targeted Integration
App 20160237457 - DeKelver; Russell ;   et al.
2016-08-18
Methods And Compositions For Modulating Pd1
App 20160220634 - Gregory; Philip D. ;   et al.
2016-08-04
Modified Zinc Finger Binding Proteins
App 20160222364 - Rebar; Edward J. ;   et al.
2016-08-04
Methods and compositions for modulating PD1
Grant 9,402,879 - Gregory , et al. August 2, 2
2016-08-02
Methods And Compositions For Increased Transgene Expression
App 20160215298 - Holmes; Michael C. ;   et al.
2016-07-28
Compositions for linking DNA-binding domains and cleavage domains
Grant 9,394,531 - Miller July 19, 2
2016-07-19
Methods and compositions for regulation of transgene expression
Grant 9,394,545 - Rebar July 19, 2
2016-07-19
Methods and compositions for inactivating glutamine synthetase gene expression
Grant 9,388,426 - Liu , et al. July 12, 2
2016-07-12
Methods And Compositions For Inactivating Alpha 1,6 Fucosyltransferase (fut8) Gene Expression
App 20160194665 - Collingwood; Trevor ;   et al.
2016-07-07
Engineered cleavage half-domains
Grant 9,376,689 - Doyon , et al. June 28, 2
2016-06-28
Linear donor constructs for targeted integration
Grant 9,376,685 - DeKelver , et al. June 28, 2
2016-06-28
Methods And Compostions For Targeted Genomic Deletion
App 20160177290 - Urnov; Fyodor ;   et al.
2016-06-23
Methods And Compositions For Enhancing Targeted Transgene Integration
App 20160168593 - Cost; Gregory J. ;   et al.
2016-06-16
Targeted Genomic Modification With Partially Single-stranded Donor Molecules
App 20160145644 - Cost; Gregory J. ;   et al.
2016-05-26
Methods And Compositions For Regulation Of Metabolic Disorders
App 20160143953 - Gregory; Philip D. ;   et al.
2016-05-26
Optimized Non-canonical Zinc Finger Proteins
App 20160130314 - Cai; Qihua C. ;   et al.
2016-05-12
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
Grant 9,322,036 - Collingwood , et al. April 26, 2
2016-04-26
DNA-binding proteins and uses thereof
Grant 9,322,005 - Gregory , et al. April 26, 2
2016-04-26
Methods And Compositions For Treatment Of A Genetic Condition
App 20160090607 - Conway; Anthony ;   et al.
2016-03-31
Methods And Compositions For Treating Trinucleotide Repeat Disorders
App 20160082081 - Gregory; Philip D. ;   et al.
2016-03-24
Methods and compositions for targeted cleavage and recombination
Grant 9,289,451 - Urnov , et al. March 22, 2
2016-03-22
Method Of Inactivating A Glucocorticoid Receptor Gene In An Isolated Cell
App 20160076056 - Reik; Andreas ;   et al.
2016-03-17
Genome Editing In Rats Using Zinc-finger Nucleases
App 20160068865 - Cui; Xiaoxia ;   et al.
2016-03-10
Methods And Compositions For The Treatment Of Lysosomal Storage Diseases
App 20160060656 - Rebar; Edward J.
2016-03-03
Methods and compositions for gene correction
Grant 9,267,123 - Jaenisch , et al. February 23, 2
2016-02-23
Targeted integration into the PPP1R12C locus
Grant 9,267,154 - DeKelver , et al. February 23, 2
2016-02-23
Methods And Compositions For Gene Correction
App 20160046683 - Jaenisch; Rudolf ;   et al.
2016-02-18
Methods And Compositions For Targeted Single-stranded Cleavage And Targeted Integration
App 20160046915 - Wang; Jianbin
2016-02-18
Targeted integration and expression on exogenous nucleic acid sequences
Grant 9,260,726 - Gregory , et al. February 16, 2
2016-02-16
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,255,259 - Cost , et al. February 9, 2
2016-02-09
Isolated mouse or human cell having an exogenous transgene in an endogenous albumin gene
Grant 9,255,250 - Gregory , et al. February 9, 2
2016-02-09
Gene Correction Of Scid-related Genes In Hematopoietic Stem And Progenitor Cells
App 20160030477 - Conway; Anthony ;   et al.
2016-02-04
Methods and compositions for targeted genomic deletion
Grant 9,249,428 - Urnov , et al. February 2, 2
2016-02-02
Methods And Compositions For Modulating Nuclease-mediated Genome Engineering In Hematopoietic Stem Cells
App 20160024474 - Conway; Anthony ;   et al.
2016-01-28
Gene Editing For Hiv Gene Therapy
App 20160022737 - Gregory; Philip D. ;   et al.
2016-01-28
Methods And Compositions For Treating Hemophilia B
App 20160022838 - Gregory; Philip D. ;   et al.
2016-01-28
Modified zinc finger binding proteins
Grant 9,238,803 - Rebar , et al. January 19, 2
2016-01-19
Screening Assays For Therapeutics For Parkinson's Disease
App 20160010154 - LAGANIERE; Josee ;   et al.
2016-01-14
Modified zinc finger binding proteins
Grant 9,234,187 - Rebar , et al. January 12, 2
2016-01-12
Engineered zinc finger proteins for treating trinucleotide repeat disorders
Grant 9,234,016 - Gregory , et al. January 12, 2
2016-01-12
Modified zinc finger binding proteins
Grant 9,234,188 - Rebar , et al. January 12, 2
2016-01-12
Methods and compositions for modification of the HPRT locus
Grant 9,222,105 - Cost , et al. December 29, 2
2015-12-29
Method of inactivating a glucocorticoid receptor gene in an isolated cell
Grant 9,217,026 - Reik , et al. December 22, 2
2015-12-22
Methods And Compositions For Nuclease Design
App 20150353917 - Miller; Jeffrey C.
2015-12-10
Method of deleting an IgM gene in an isolated rat cell
Grant 9,206,404 - Cui , et al. December 8, 2
2015-12-08
Methods And Compositions For Regulation Of Transgene Expression
App 20150344893 - Rebar; Edward J.
2015-12-03
Methods and compositions for targeted single-stranded cleavage and targeted integration
Grant 9,200,266 - Wang December 1, 2
2015-12-01
Methods And Compositions For Treating Huntington's Disease
App 20150335708 - Froelich; Steven ;   et al.
2015-11-26
Methods And Compositions For Prevention Or Treatment Of A Disease
App 20150329875 - Gregory; Philip D. ;   et al.
2015-11-19
Optimized non-canonical zinc finger proteins
Grant 9,187,758 - Cai , et al. November 17, 2
2015-11-17
Methods and compositions for treating hemophilia B
Grant 9,175,280 - Gregory , et al. November 3, 2
2015-11-03
Engineered Transcription Activator Like Effector (tale) Proteins
App 20150307561 - Miller; Jeffrey C. ;   et al.
2015-10-29
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
Grant 9,161,995 - Guschin , et al. October 20, 2
2015-10-20
Compositions for linking zinc finger modules
Grant 9,163,245 - Paschon , et al. October 20, 2
2015-10-20
Engineered cleavage half-domains
Grant 9,150,879 - Doyon , et al. October 6, 2
2015-10-06
Methods and compositions for regulation of transgene expression
Grant 9,150,847 - Rebar October 6, 2
2015-10-06
Methods And Compositions For Regulating Hiv Infection
App 20150267223 - Holmes; Michael C. ;   et al.
2015-09-24
Methods And Compositions For Regulation Of Zinc Finger Protein Expression
App 20150267205 - Froelich; Steven ;   et al.
2015-09-24
Methods And Compositions For Modification Of A Hla Locus
App 20150252094 - Collingwood; Trevor ;   et al.
2015-09-10
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
Grant 9,121,072 - Holmes , et al. September 1, 2
2015-09-01
Methods And Compositions For Nuclease-mediated Targeted Integration
App 20150240263 - Holmes; Michael C. ;   et al.
2015-08-27
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
Grant 9,115,409 - Doyon , et al. August 25, 2
2015-08-25
Linear Donor Constructs For Targeted Integration
App 20150225727 - DeKelver; Russell ;   et al.
2015-08-13
Methods And Compositions For Treatment Of A Beta Thalessemia
App 20150218253 - Liu; Pei-Qi ;   et al.
2015-08-06
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering In Hematopoietic Stem Cells
App 20150174169 - Genovese; Pietro ;   et al.
2015-06-25
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases
App 20150164954 - Bonini; Maria Chiara ;   et al.
2015-06-18
Methods And Compositions For Treating Hemophilia
App 20150166618 - Miller; Jeffrey C. ;   et al.
2015-06-18
Methods And Compositions For Genome Engineering
App 20150159172 - Miller; Jeffrey C. ;   et al.
2015-06-11
Engineered Cleavage Half-domains
App 20150159176 - Doyon; Yannick ;   et al.
2015-06-11
Linear donor constructs for targeted integration
Grant 9,045,763 - DeKelver , et al. June 2, 2
2015-06-02
Nuclease-mediated Regulation Of Gene Expression
App 20150132269 - Orkin; Stuart H. ;   et al.
2015-05-14
Modification Of Cxcr4 Using Engineered Zinc Finger Proteins
App 20150110757 - Holmes; Michael C. ;   et al.
2015-04-23
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering
App 20150110762 - Holmes; Michael C. ;   et al.
2015-04-23
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,005,973 - Cost , et al. April 14, 2
2015-04-14
Methods And Compositions For Inactivating Glutamine Synthetase Gene Expression
App 20150087067 - Liu; Pei-Qi ;   et al.
2015-03-26
Compositions For Linking Dna-binding Domains And Cleavage Domains
App 20150064789 - Paschon; David ;   et al.
2015-03-05
Fad3 Performance Loci And Corresponding Target Site Specific Binding Proteins Capable Of Inducing Targeted Breaks
App 20150067921 - Cogan; Noel ;   et al.
2015-03-05
Engineered Zinc Finger Proteins Targeting 5-enolpyruvyl Shikimate-3-phosphate Synthase Genes
App 20150064790 - Gupta; Manju ;   et al.
2015-03-05
Methods And Compositions For Treatment Of A Genetic Condition
App 20150056705 - Conway; Anthony ;   et al.
2015-02-26
Engineered cleavage half-domains
Grant 8,962,281 - Doyon , et al. February 24, 2
2015-02-24
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
Grant 8,956,828 - Bonini , et al. February 17, 2
2015-02-17
Methods And Compositions For Modification Of Hla
App 20150037304 - Gregory; Philip D. ;   et al.
2015-02-05
Methods and compositions for modification of a HLA locus
Grant 8,945,868 - Collingwood , et al. February 3, 2
2015-02-03
Methods And Compositions For Targeted Genomic Deletion
App 20150031090 - Urnov; Fyodor ;   et al.
2015-01-29
Methods and compositions for targeted integration
Grant 8,936,936 - Holmes , et al. January 20, 2
2015-01-20
Optimized non-canonical zinc finger proteins
Grant 8,921,112 - Cai , et al. December 30, 2
2014-12-30
Methods And Compositions For Targeted Cleavage And Recombination
App 20140369980 - Holmes; Michael C. ;   et al.
2014-12-18
DNA-binding proteins and uses thereof
Grant 8,912,138 - Gregory , et al. December 16, 2
2014-12-16
Targeted Integration Into The Ppp1r12c Locus
App 20140349394 - DeKelver; Russell ;   et al.
2014-11-27
Methods and compositions for modification of the HPRT locus
Grant 8,895,264 - Cost , et al. November 25, 2
2014-11-25
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
Grant 8,889,390 - Gupta , et al. November 18, 2
2014-11-18
Delivery Methods And Compositions For Nuclease-mediated Genome Engineering
App 20140335063 - Cannon; Paula M. ;   et al.
2014-11-13
Methods And Compositions For Treating Huntington's Disease
App 20140336133 - Miller; Jeffrey C. ;   et al.
2014-11-13
Regulation Of Endogenous Gene Expression In Cells Using Zinc Finger Proteins
App 20140325691 - Cox III; George Norbert ;   et al.
2014-10-30
Modification of CXCR4 using engineered zinc finger proteins
Grant 8,871,905 - Holmes , et al. October 28, 2
2014-10-28
Methods And Compositions For Integration Of An Exogenous Sequence Within The Genome Of Plants
App 20140304853 - Ainley; W. Michael ;   et al.
2014-10-09
Targeted Disruption Of T Cell Receptor Genes Using Engineered Zinc Finger Protein Nucleases
App 20140301990 - Gregory; Philip D. ;   et al.
2014-10-09
Compositions For Linking Zinc Finger Modules
App 20140287500 - Paschon; David ;   et al.
2014-09-25
Methods and compositions for treating Huntington's Disease
Grant 8,841,260 - Miller , et al. September 23, 2
2014-09-23
Methods And Compositions For Inactivating Alpha 1,6 Fucosyltransferase (fut8) Gene Expression
App 20140273097 - Collingwood; Trevor ;   et al.
2014-09-18
Targeted integration into the PPP1R12C locus
Grant 8,822,221 - DeKelver , et al. September 2, 2
2014-09-02
Methods And Compositions For Enhancing Nuclease-mediated Gene Disruption
App 20140242702 - Chen; Fuqiang ;   et al.
2014-08-28
Modulation Of Stem Cells Using Zinc Finger Proteins
App 20140234970 - Wolffe; Alan P. ;   et al.
2014-08-21
Methods And Compositions For Targeted Single-stranded Cleavage And Targeted Integration
App 20140212928 - Wang; Jianbin
2014-07-31
Methods And Compositions For Alteration Of A Cystic Fibrosis Transmembrane Conductance Regulator (cftr) Gene
App 20140205579 - Davis; Brian R. ;   et al.
2014-07-24
Methods And Compositions For Increased Transgene Expression
App 20140205576 - Holmes; Michael C. ;   et al.
2014-07-24
Compositions for linking zinc finger modules
Grant 8,772,453 - Paschon , et al. July 8, 2
2014-07-08
Methods and compositions for increasing nuclease activity
Grant 8,772,008 - Doyon July 8, 2
2014-07-08
Genome editing of a Rosa locus using zinc-finger nucleases
Grant 8,771,985 - Cui , et al. July 8, 2
2014-07-08
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
Grant 8,772,025 - Collingwood , et al. July 8, 2
2014-07-08
Methods and compositions for increasing nuclease activity
Grant 8,772,009 - Doyon July 8, 2
2014-07-08
Engineered cleavage half-domains
Grant 8,771,986 - Miller July 8, 2
2014-07-08
Methods And Compositions For Regulation Of Metabolic Disorders
App 20140155468 - Gregory; Philip D. ;   et al.
2014-06-05
Engineered Zinc Finger Proteins Targeting Plant Genes Involved In Fatty Acid Biosynthesis
App 20140157458 - DeKelver; Russell ;   et al.
2014-06-05
Modulation of stem cells using zinc finger proteins
Grant 8,735,153 - Wolffe , et al. May 27, 2
2014-05-27
Methods And Compositions For Muscular Dystrophies
App 20140140969 - Beausejour; Christian ;   et al.
2014-05-22
Novel Dna-binding Proteins And Uses Thereof
App 20140134740 - Gregory; Philip D. ;   et al.
2014-05-15
Novel Dna-binding Proteins And Uses Thereof
App 20140134723 - Gregory; Philip D. ;   et al.
2014-05-15
Novel Dna-binding Proteins And Uses Thereof
App 20140134741 - Gregory; Philip D. ;   et al.
2014-05-15
Methods And Compositions For Gene Inactivation
App 20140127811 - Ando; Dale ;   et al.
2014-05-08
T Cell Modifying Compounds And Uses Thereof
App 20140120622 - Gregory; Philip D. ;   et al.
2014-05-01
Engineered Cleavage Half-domains
App 20140120612 - Doyon; Yannick ;   et al.
2014-05-01
Methods and compositions for targeted single-stranded cleavage and targeted integration
Grant 8,703,489 - Wang April 22, 2
2014-04-22
Methods And Compositions For Treatment Of A Genetic Condition
App 20140093913 - Cost; Gregory J. ;   et al.
2014-04-03
Fad2 Performance Loci And Corresponding Target Site Specific Binding Proteins Capable Of Inducing Targeted Breaks
App 20140090112 - Cogan; Noel ;   et al.
2014-03-27
Fad2 Performance Loci And Corresponding Target Site Specific Binding Proteins Capable Of Inducing Targeted Breaks
App 20140090116 - Ainley; William Michael ;   et al.
2014-03-27
Zinc finger proteins for DNA binding and gene regulation in plants
Grant 8,680,021 - Jamieson , et al. March 25, 2
2014-03-25
Methods And Compositions For Treatment Of A Genetic Condition
App 20140080216 - Cost; Gregory J. ;   et al.
2014-03-20
Targeted Deletion Of Cellular Dna Sequences
App 20140065667 - Guschin; Dmitry ;   et al.
2014-03-06
Methods And Compositions For Modulating Pd1
App 20140030240 - Gregory; Philip D. ;   et al.
2014-01-30
Methods And Compositions For Delivery Of Biologics
App 20140017214 - Cost; Gregory J.
2014-01-16
Methods And Compositions For The Treatment Of Lysosomal Storage Diseases
App 20140017212 - Rebar; Edward J.
2014-01-16
Engineered cleavage half-domains
Grant 8,623,618 - Doyon , et al. January 7, 2
2014-01-07
Methods And Compositions For Nuclease-mediated Targeted Integration Of Transgenes
App 20130326645 - Cost; Gregory J. ;   et al.
2013-12-05
Targeted Modification Of Malate Dehydrogenase
App 20130326725 - Shukla; Vipula ;   et al.
2013-12-05
Methods and compositions for generation of Bax-and Bak-deficient cell lines
Grant 8,597,912 - Collingwood , et al. December 3, 2
2013-12-03
Engineered zinc finger proteins targeting plant genes involved in fatty acid biosynthesis
Grant 8,592,645 - DeKelver , et al. November 26, 2
2013-11-26
DNA-binding proteins and uses thereof
Grant 8,586,526 - Gregory , et al. November 19, 2
2013-11-19
Methods and compositions for gene inactivation
Grant 8,569,253 - Ando , et al. October 29, 2
2013-10-29
Methods and compositions for modulating PD1
Grant 8,563,314 - Gregory , et al. October 22, 2
2013-10-22
Methods and compositions for treating neuropathies
Grant 8,551,945 - Dent , et al. October 8, 2
2013-10-08
Taregted Integration And Expression Of Exogenous Nucleic Acid Sequences
App 20130244332 - Gregory; Philip D. ;   et al.
2013-09-19
Methods and compositions for targeted cleavage and recombination
Grant 8,524,500 - Urnov , et al. September 3, 2
2013-09-03
Position dependent recognition of GNN nucleotide triplets by zinc fingers
Grant 8,524,874 - Liu , et al. September 3, 2
2013-09-03
Methods and compositions for gene inactivation
Grant 8,524,221 - Ando , et al. September 3, 2
2013-09-03
Methods And Compostitions For Gene Editing Of A Pathogen
App 20130216579 - Fidock; David ;   et al.
2013-08-22
Modified Dna-binding Proteins And Uses Thereof
App 20130196373 - Gregory; Philip D. ;   et al.
2013-08-01
Methods And Compositions For Regulation Of Transgene Expression
App 20130177960 - Rebar; Edward J.
2013-07-11
Methods And Compositions For Regulating Hiv Infection
App 20130171732 - Holmes; Michael C. ;   et al.
2013-07-04
Rapid Screening Of Biologically Active Nucleases And Isolation Of Nuclease-modified Cells
App 20130171657 - Doyon; Yannick ;   et al.
2013-07-04
Methods And Compositions For Inactivating Glutamine Synthetase Gene Expression
App 20130164785 - Liu; Pei-Qi ;   et al.
2013-06-27
Nucleic acid encoding a zinc finger that recognizes the sodium channel Nav 1.8 (PN3) gene
Grant 8,466,267 - Collingwood June 18, 2
2013-06-18
Methods And Compositions For Modification Of The Hprt Locus
App 20130137104 - Cost; Gregory J. ;   et al.
2013-05-30
Methods And Compositions For Modification Of The Hprt Locus
App 20130122591 - Cost; Gregory J. ;   et al.
2013-05-16
Position Dependent Recognition Of Gnn Nucleotide Triplets By Zinc Fingers
App 20130123484 - Liu; Qiang ;   et al.
2013-05-16
Targeted deletion of cellular DNA sequences
Grant 8,409,861 - Guschin , et al. April 2, 2
2013-04-02
Position dependent recognition of GNN nucleotide triplets by zinc fingers
Grant 8,383,766 - Liu , et al. February 26, 2
2013-02-26
Methods for targeted cleavage and recombination of CCR5
Grant 8,349,810 - Miller , et al. January 8, 2
2013-01-08
Targeted integration into the Zp15 locus
Grant 8,329,986 - Butler , et al. December 11, 2
2012-12-11
Methods And Compositions For Gene Inactivation
App 20120309091 - Ando; Dale ;   et al.
2012-12-06
Methods and Compositions for Gene Inactivation
App 20120308528 - Ando; Dale ;   et al.
2012-12-06
Regulation of endogenous gene expression in cells using zinc finger proteins
App 20120294838 - Cox III; George Norbert ;   et al.
2012-11-22
Zinc finger proteins and method for inactivating a dhfr gene in a chinese hamster ovary cell
Grant 8,313,925 - Gregory , et al. November 20, 2
2012-11-20
Methods And Compositions For Increasing Production Of Induced Pluripotent Stem Cells (ipscs)
App 20120252122 - LAGANIERE; Josee
2012-10-04
Rapid Screening Of Biologically Active Nucleases And Isolation Of Nuclease-modified Cells
App 20120237926 - Holmes; Michael C. ;   et al.
2012-09-20
Repressing endogenous CCR5 gene expression in cells using engineered zinc finger proteins
Grant 8,268,618 - Cox, III , et al. September 18, 2
2012-09-18
Methods And Compositions For Treating Occular Disorders
App 20120204282 - ZHANG; H. Steve
2012-08-09
Engineered Cleavage Half-domains
App 20120142062 - DOYON; Yannick ;   et al.
2012-06-07
Targeted Integration Into The Ppp1r12c Locus
App 20120142055 - DeKelver; Russell ;   et al.
2012-06-07
Methods And Compositions For Inhibiting Viral Entry Into Cells
App 20120093787 - HOLMES; Michael C. ;   et al.
2012-04-19
Methods And Compositions For Analysis Of Regulatory Sequences
App 20120088677 - URNOV; Fyodor ;   et al.
2012-04-12
Methods and compositions for inactivating glutamine synthetase gene expression
Grant 8,153,399 - Liu , et al. April 10, 2
2012-04-10
Engineered Cleavage Half-domains
App 20120040398 - MILLER; Jeffrey C.
2012-02-16
Targeted integration into the PPP1R12C locus
Grant 8,110,379 - DeKelver , et al. February 7, 2
2012-02-07
Methods And Compositions For Treating Neuropathic Pain
App 20110306559 - Forsayeth; John R.M. ;   et al.
2011-12-15
Novel DNA-binding proteins and uses thereof
App 20110301073 - Gregory; Philip D. ;   et al.
2011-12-08
Targeted modification of chromatin structure
Grant 8,071,370 - Wolffe , et al. December 6, 2
2011-12-06
Regulation of angiogenesis with zinc finger proteins
Grant 8,071,564 - Rebar , et al. December 6, 2
2011-12-06
Targeted genomic modification with partially single-stranded donor molecules
App 20110287545 - Cost; Gregory J. ;   et al.
2011-11-24
Compositions for linking zinc finger modules
App 20110287512 - Paschon; David ;   et al.
2011-11-24
Linear donor constructs for targeted integration
App 20110281361 - DeKelver; Russell ;   et al.
2011-11-17
Methods and compositions for increasing nuclease activity
App 20110269234 - Doyon; Yannick
2011-11-03
Genome editing of a Rosa locus using nucleases
App 20110265198 - Gregory; Philip D. ;   et al.
2011-10-27
Engineered cleavage half-domains
Grant 8,034,598 - Miller October 11, 2
2011-10-11
Organisms homozygous for targeted modification
App 20110247089 - Doyon; Yannick
2011-10-06
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
App 20110244474 - Holmes; Michael C. ;   et al.
2011-10-06
Anti-angiogenic methods and compositions
Grant 8,012,946 - Zhang , et al. September 6, 2
2011-09-06
Targeted genomic modification with partially single-stranded donor molecules
App 20110207221 - Cost; Gregory J. ;   et al.
2011-08-25
Regulation of endogenous gene expression in cells using zinc finger proteins
Grant 7,985,887 - Cox, III , et al. July 26, 2
2011-07-26
Methods and compositions for targeted cleavage and recombination
Grant 7,972,854 - Miller , et al. July 5, 2
2011-07-05
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
App 20110158957 - Bonini; Maria Chiara ;   et al.
2011-06-30
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
App 20110159541 - Collingwood; Trevor ;   et al.
2011-06-30
Methods and compositions for modulating PD1
App 20110136895 - Gregory; Philip D. ;   et al.
2011-06-09
Methods and compositions for gene inactivation
Grant 7,951,925 - Ando , et al. May 31, 2
2011-05-31
Compositions and methods for regulation of plant gamma-tocopherol methyltransferase
Grant 7,947,873 - Li , et al. May 24, 2
2011-05-24
Randomized libraries of zinc finger proteins
Grant 7,943,553 - Case , et al. May 17, 2
2011-05-17
Simultaneous modulation of multiple genes
Grant 7,939,327 - Miller , et al. May 10, 2
2011-05-10
Libraries of regulatory sequences, methods of making and using same
Grant 7,923,542 - Wolffe , et al. April 12, 2
2011-04-12
Methods and compositions for treating trinucleotide repeat disorders
App 20110082093 - GREGORY; PHILIP D. ;   et al.
2011-04-07
Methods and compositions for treating neuropathies
App 20110082078 - Dent; Carolyn ;   et al.
2011-04-07
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
Grant 7,919,313 - Collingwood , et al. April 5, 2
2011-04-05
Engineered cleavage half-domains
Grant 7,914,796 - Miller , et al. March 29, 2
2011-03-29
Anti-angiogenic methods and compositions
Grant 7,893,022 - Zhang , et al. February 22, 2
2011-02-22
Organisms homozygous for targeted modification
App 20110041195 - Doyon; Yannick
2011-02-17
Targeted integration into stem cells
App 20110027235 - Gregory; Philip D. ;   et al.
2011-02-03
Methods and compositions for targeted cleavage and recombination
App 20110030076 - Urnov; Fyodor ;   et al.
2011-02-03
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
App 20110014616 - HOLMES; MICHAEL C. ;   et al.
2011-01-20
Targeted modification of chromatin structure
App 20100323424 - Wolffe; Alan P. ;   et al.
2010-12-23
Methods and compositions for inactivating glutamine synthetase gene expression
App 20100311124 - Liu; Pei-Qi ;   et al.
2010-12-09
Modification of CXCR4 using engineered zinc finger proteins
App 20100291048 - Holmes; Michael C. ;   et al.
2010-11-18
Alteration of tumor growth using zinc finger proteins
App 20100279406 - Cox, III; George Norbert ;   et al.
2010-11-04
Regulation of endogenous gene expression in cells using zinc finger proteins
App 20100261271 - Cox, III; George Norbert ;   et al.
2010-10-14
Methods and compositions for treating neuropathic and neurodegenerative conditions
App 20100256221 - Martin; J. Tyler
2010-10-07
Genome editing in rats using zinc-finger nucleases
App 20100218264 - Cui; Xiaoxia ;   et al.
2010-08-26
Methods and compositions for inactivating glutamine synthetase gene expression
App 20100129869 - Liu; Pei-Qi ;   et al.
2010-05-27
Methods and compositions for gene inactivation
App 20100111907 - Ando; Dale ;   et al.
2010-05-06
Regulation Of Angiogenesis With Zinc Finger Proteins
App 20100093838 - Rebar; Edward ;   et al.
2010-04-15
Methods and compositions for targeted single-stranded cleavage and targeted integration
App 20100047805 - Wang; Jianbin
2010-02-25
Methods and compositions for generation of Bax-and Bak-deficient cell lines
App 20100003756 - Collingwood; Trevor ;   et al.
2010-01-07
Engineered cleavage half-domains
App 20090311787 - Miller; Jeffrey C.
2009-12-17
Engineered cleavage half-domains
App 20090305346 - Miller; Jeffrey C.
2009-12-10
Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
App 20090305402 - Liljedahl; Monika ;   et al.
2009-12-10
Compositions for linking DNA-binding domains and cleavage domains
App 20090305419 - Miller; Jeffrey C.
2009-12-10
Linear donor constructs for targeted integration
App 20090263900 - DeKelver; Russell ;   et al.
2009-10-22
Targeted integration and expression of exogenous nucleic acid sequences
App 20090258363 - Gregory; Philip D. ;   et al.
2009-10-15
Treatment Of Chronic Pain With Zinc Finger Proteins
App 20090215878 - TAN; SIYUAN ;   et al.
2009-08-27
Genomic editing in zebrafish using zinc finger nucleases
App 20090203140 - AMACHER; SHARON ;   et al.
2009-08-13
Modulation of gene expression using insulator binding proteins
App 20090181455 - Wolffe; Alan P. ;   et al.
2009-07-16
Methods and compositions for targeted integration
App 20090117617 - Holmes; Michael C. ;   et al.
2009-05-07
Treatment of neuropathic pain with zinc finger proteins
App 20090069259 - Collingwood; Trevor
2009-03-12
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
App 20090042250 - Collingwood; Trevor ;   et al.
2009-02-12
Targeted modification of chromatin structure
App 20090023153 - Wolffe; Alan P. ;   et al.
2009-01-22
Methods and compositions for increased transgene expression
App 20080311095 - Holmes; Michael C. ;   et al.
2008-12-18
Targeted integration into the PPP1R12C locus
App 20080299580 - DeKelver; Russell ;   et al.
2008-12-04
Simultaneous modulation of multiple genes
App 20080233641 - Miller; Jeffrey ;   et al.
2008-09-25
Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
App 20080209587 - Liljedahl; Monika ;   et al.
2008-08-28
Anti-angiogenic methods and compositions
App 20080187523 - Zhang; H. Steve ;   et al.
2008-08-07
Engineered cleavage half-domains
App 20080131962 - Miller; Jeffrey C.
2008-06-05
Anti-angiogenic methods and compositions
App 20080118469 - Zhang; H. Steve ;   et al.
2008-05-22
Anti-angiogenic methods and compositions
App 20080108556 - Zhang; H. Steve ;   et al.
2008-05-08
Regulated gene expression in plants
App 20080070306 - Choo; Yen ;   et al.
2008-03-20
Methods and compositions for inactivation of dihydrofolate reductase
App 20080015164 - Collingwood; Trevor
2008-01-17
Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
App 20070287189 - Eisenberg; Stephen P. ;   et al.
2007-12-13
Methods and compositions for targeted cleavage and recombination
App 20070218528 - Miller; Jeffrey C.
2007-09-20
Targeted integration and expression of exogenous nucleic acid sequences
App 20070134796 - Holmes; Michael C. ;   et al.
2007-06-14
Regulation of angiogenesis with zinc finger proteins
App 20070072818 - Rebar; Edward ;   et al.
2007-03-29

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