Leppla; Stephen H.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Leppla; Stephen H..The latest application filed is for "monoclonal antibodies that neutralize anthrax protective antigen (pa) toxin".

Company Profile

4.36.36

Leppla; Stephen H. - Bethesda MD
Leppla; Stephen H - Rockville MD
Leppla; Stephen H. - Rockville MD

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.

Patent Activity

Patent	Date
Modified anthrax toxin protective antigen Grant 10,835,593 - Liu , et al. November 17, 2	2020-11-17
Monoclonal Antibodies that Neutralize Anthrax Protective Antigen (PA) Toxin App 20190144527 - CHEN; Zhaochun ; et al.	2019-05-16
Antibodies to tumor endothelial marker 8 Grant 10,273,299 - Frankel , et al.	2019-04-30
Protease-deficient bacillus anthracis Grant 10,273,548 - Pomerantsev , et al.	2019-04-30
Monoclonal antibodies that neutralize anthrax protective antigen (PA) toxin Grant 10,227,395 - Chen , et al.	2019-03-12
Modified Anthrax Toxin Protective Antigen App 20180250376 - Liu; Shi-Hui ; et al.	2018-09-06
Monoclonal antibodies that neutralize anthrax toxins Grant 10,053,503 - Chen , et al. August 21, 2	2018-08-21
Monoclonal Antibodies that Neutralize Anthrax Toxins App 20180111981 - CHEN; Zhaochun ; et al.	2018-04-26
Cytolethal distending toxin subunit B conjugated or fused to Bacillus anthracis toxin lethal factor Grant 9,890,369 - Bachran , et al. February 13, 2	2018-02-13
Engineered anthrax lethal toxin for targeted delivery Grant 9,730,993 - Leysath , et al. August 15, 2	2017-08-15
Protease-deficient Bacillus Anthracis App 20170145525 - POMERANTSEV; Andrei P. ; et al.	2017-05-25
Monoclonal antibodies that neutralize anthrax toxins Grant 9,580,492 - Chen , et al. February 28, 2	2017-02-28
Protease-deficient Bacillus anthracis Grant 9,555,064 - Pomerantsev , et al. January 31, 2	2017-01-31
Antibodies To Tumor Endothelial Marker 8 App 20160319016 - FRANKEL; Arthur E. ; et al.	2016-11-03
Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors Grant 9,403,872 - Leppla , et al. August 2, 2	2016-08-02
Monoclonal Antibodies That Neutralize Anthrax Toxins App 20160200803 - CHEN; Zhaochun ; et al.	2016-07-14
Cytolethal Distending Toxin Subunit B Conjugated Or Fused To Bacillus Anthracis Toxin Lethal Factor App 20160145590 - Bachran; Christopher H. ; et al.	2016-05-26
Antibodies to tumor endothelial marker 8 Grant 9,309,322 - Frankel , et al. April 12, 2	2016-04-12
Engineered Anthrax Lethal Toxin For Targeted Delivery App 20150224184 - Leysath; Clinton Edward ; et al.	2015-08-13
Use Of Saccharides Cross-reactive With Bacillus Anthracis Spore Glycoprotein As A Vaccine Against Anthrax App 20150093412 - Kubler-Kielb; Joanna ; et al.	2015-04-02
Monoclonal antibodies that neutralize anthrax toxins Grant 8,961,975 - Chen , et al. February 24, 2	2015-02-24
Monoclonal Antibodies That Neutralize Anthrax Toxins App 20150017153 - CHEN; Zhaochun ; et al.	2015-01-15
Use of saccharides cross-reactive with Bacillus anthracis spore glycoprotein as a vaccine against anthrax Grant 8,926,986 - Kubler-Kielb , et al. January 6, 2	2015-01-06
Mutated Anthrax Toxin Protective Antigen Proteins That Specifically Target Cells Containing High Amounts Of Cell-surface Metalloproteinases Or Plasminogen Activator Receptors App 20140378654 - LEPPLA; Stephen H. ; et al.	2014-12-25
Protease-deficient Bacillus Anthracis App 20140314716 - Pomerantsev; Andrei P. ; et al.	2014-10-23
Monoclonal Antibodies that Neutralize Anthrax Protective Antigen (PA) Toxin App 20140227257 - CHEN; Zhaochun ; et al.	2014-08-14
Methods of using Bacillus anthracis protective antigen sequences for vaccination Grant 8,703,150 - Leppla , et al. April 22, 2	2014-04-22
Monoclonal antibodies that neutralize anthrax toxins Grant 8,574,853 - Chen , et al. November 5, 2	2013-11-05
Use Of Saccharides Cross-reactive With Bacillus Anthracis Spore Glycoprotein As A Vaccine Against Anthrax App 20130273097 - Kubler-Kielb; Joanna ; et al.	2013-10-17
Methods for preparing immunogenic conjugates Grant 8,481,048 - Schneerson , et al. July 9, 2	2013-07-09
Recombinant modified Bacillus anthracis protective antigen for use in vaccines Grant 8,394,387 - Leppla , et al. March 12, 2	2013-03-12
Recombinant Modified Bacillus Anthracis Protective Antigen For Use In Vaccines App 20130058967 - Leppla; Stephen H. ; et al.	2013-03-07
Multimeric protein toxins to target cells having multiple identifying characteristics Grant 8,388,933 - Leppla , et al. March 5, 2	2013-03-05
Monoclonal Antibodies That Neutralize Anthrax Toxins App 20120171196 - CHEN; Zhaochun ; et al.	2012-07-05
Bacillus Anthracis Protective Antigen Sequences App 20120009219 - Leppla; Stephen H. ; et al.	2012-01-12
Monoclonal antibodies that neutralize anthrax toxins Grant 8,071,100 - Chen , et al. December 6, 2	2011-12-06
Multimeric Protein Toxins To Target Cells Having Multiple Identifying Characteristics App 20110280908 - Leppla; Stephen H. ; et al.	2011-11-17
Bacillus anthracis protective antigen nucleic acid sequences Grant 8,044,189 - Leppla , et al. October 25, 2	2011-10-25
Multimeric protein toxins to target cells having multiple identifying characteristics Grant 7,947,289 - Leppla , et al. May 24, 2	2011-05-24
Use Of Saccharides Cross-reactive With Bacillus Anthracis Spore Glycoprotein As A Vaccine Against Anthrax App 20100330074 - Kubler-Kielb; Joanna ; et al.	2010-12-30
Bacillus Anthracis Protective Antigen Nucleic Acid Sequences App 20100272757 - Leppla; Stephen H. ; et al.	2010-10-28
Methods for preparing Bacillus anthracis protective antigen for use in vaccines Grant 7,763,451 - Shiloach , et al. July 27, 2	2010-07-27
Human Cancer Therapy Using Engineered Matrix Metalloproteinase-activated Anthrax Lethal Toxin That Targets Tumor Vasculatuture App 20100168012 - Leppla; Stephen H. ; et al.	2010-07-01
Monoclonal Antibodies That Neutralize Anthrax Toxins App 20100119520 - Chen; Zhaochun ; et al.	2010-05-13
Methods For Preparing Immunogenic Conjugates App 20100040644 - Schneerson; Rachel ; et al.	2010-02-18
Methods for preparing immunogenic conjugates Grant 7,625,736 - Schneerson , et al. December 1, 2	2009-12-01
Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors App 20090142794 - Leppla; Stephen H. ; et al.	2009-06-04
Mutated anthrax toxin protective antigen proteins that specifically target cells containing high amounts of cell-surface metalloproteinases or plasminogen activator receptors Grant 7,468,352 - Leppla , et al. December 23, 2	2008-12-23
Activation of Recombinant Diphtheria Toxin Fusion Proteins by Specific Proteases Highly Expressed on the Surface of Tumor Cells App 20080166375 - Leppla; Stephen H. ; et al.	2008-07-10
Recombinant modified Bacillus anthracis protective antigen for use in vaccines Grant 7,261,900 - Leppla , et al. August 28, 2	2007-08-28
Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein Grant 7,097,965 - Klimpel , et al. August 29, 2	2006-08-29
Methods and formulations comprising agonists and antagonists of nuclear hormone receptors App 20060035813 - Sternberg; Esther M. ; et al.	2006-02-16
Methods for preparing immunogenic conjugates App 20050271675 - Schneerson, Rachel ; et al.	2005-12-08
Multimeric protein toxins to target cells having multiple identifying characteristics App 20050255083 - Leppla, Stephen H. ; et al.	2005-11-17
Imaging the activity of extracellular protease in cells using mutant anthrax toxin protective antigens that are cleaved by specific extracellular proteases App 20050123476 - Bugge, Thomas H. ; et al.	2005-06-09
Methods for preparing Bacillus anthracis sporulation deficient mutants and for producing recombinant Bacillus anthracis protective antigen for use in vaccines App 20040171121 - Leppla, Stephen H. ; et al.	2004-09-02
Methods for preparing bacillus anthracis protective antigen for use in vaccines App 20040076638 - Shiloach, Joseph ; et al.	2004-04-22
Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein App 20030198651 - Klimpel, Kurt ; et al.	2003-10-23
Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein Grant 6,592,872 - Klimpel , et al. July 15, 2	2003-07-15
Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein App 20020048590 - Klimpel, Kurt ; et al.	2002-04-25
Anthrax toxin fusion proteins and related methods Grant 5,677,274 - Leppla , et al. October 14, 1	1997-10-14
Anthrax toxin fusion proteins, nucleic acid encoding same Grant 5,591,631 - Leppla , et al. January 7, 1	1997-01-07

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