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Method for making antibody Fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof Grant 11,421,022 - Fenn , et al. August 23, 2 | 2022-08-23 |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof Grant 11,407,836 - Fenn , et al. August 9, 2 | 2022-08-09 |
Activity assay for bond forming enzymes Grant 11,169,146 - Boenitz-Dulat , et al. November 9, 2 | 2021-11-09 |
Enzymatic one-pot reaction for double polypeptide conjugation in a single step Grant 11,162,127 - Heindl , et al. November 2, 2 | 2021-11-02 |
Recombinant polypeptide production methods Grant 11,098,338 - Kopetzki , et al. August 24, 2 | 2021-08-24 |
Fusion Proteins For Ophthalmology With Increased Eye Retention App 20210024624 - HUELSMANN; Michael ;   et al. | 2021-01-28 |
Fusion proteins for opthalmology with increased eye retention Grant 10,836,816 - Huelsmann , et al. November 17, 2 | 2020-11-17 |
Method for selecting polypeptide producing cells App 20200157189 - Kopetzki; Erhard ;   et al. | 2020-05-21 |
Rapid Method For Cloning And Expression Of Cognate Antibody Variable Gene Segments App 20190382469 - Hoege; Simone ;   et al. | 2019-12-19 |
Recombinant Polypeptide Production Methods App 20190271021 - KOPETZKI; Erhard ;   et al. | 2019-09-05 |
Recombinant polypeptide production methods Grant 10,370,692 - Kopetzki , et al. | 2019-08-06 |
Protein Expression From Multiple Nucleic Acids App 20190233842 - GOEPFERT; Ulrich ;   et al. | 2019-08-01 |
Fusion Proteins For Opthalmology With Increased Eye Retention App 20190225676 - Huelsmann; Michael ;   et al. | 2019-07-25 |
Glycosylated Repeat-motif-molecule Conjugates App 20190135901 - FISCHER; STEPHAN ;   et al. | 2019-05-09 |
Glycosylated repeat-motif-molecule conjugates Grant 10,280,214 - Fischer , et al. | 2019-05-07 |
Method For Selection And Production Of Tailor-made Highly Selective And Multi-specific Targeting Entities Containing At Least Two Different Binding Entities And Uses Thereof App 20190002570 - FENN; Sebastian ;   et al. | 2019-01-03 |
Use of an amino acid auxotrophy cured prokaryotic strain for the recombinant production of a polypeptide Grant 10,155,970 - Kopetzki , et al. Dec | 2018-12-18 |
Bispecific antibodies Grant 10,106,600 - Brinkmann , et al. October 23, 2 | 2018-10-23 |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof Grant 10,106,612 - Fenn , et al. October 23, 2 | 2018-10-23 |
Method For The Expression Of Polypeptides Using Modified Nucleic Acids App 20180100006 - Klostermann; Stefan ;   et al. | 2018-04-12 |
Promoter Grant 9,926,567 - Klein , et al. March 27, 2 | 2018-03-27 |
Activity Assay For Bond Forming Enzymes App 20170370913 - Boenitz-Dulat; Mara ;   et al. | 2017-12-28 |
Enzymatic One-pot Reaction For Double Polypeptide Conjugation In A Single Step App 20170314055 - Heindl; Dieter ;   et al. | 2017-11-02 |
Rapid Method For Cloning And Expression Of Cognate Antibody Variable Region Gene Segments App 20170210785 - Hoege; Simone ;   et al. | 2017-07-27 |
METHOD AND CONSTRUCTS FOR THE pH DEPENDENT PASSAGE OF THE BLOOD-BRAIN-BARRIER App 20170174776 - Bohrmann; Bernd ;   et al. | 2017-06-22 |
Protein Expression From Multiple Nucleic Acids App 20170166923 - Goepfert; Ulrich ;   et al. | 2017-06-15 |
Improved Recombinant Polypeptide Production Methods App 20160326562 - KOPETZKI; Erhard ;   et al. | 2016-11-10 |
Method for reduction of 1->2 reading frame shifts Grant 9,487,576 - Grossmann , et al. November 8, 2 | 2016-11-08 |
Serpin-finger fusion polypeptide Grant 9,403,896 - Engh , et al. August 2, 2 | 2016-08-02 |
Multispecific antibodies comprising full length antibodies and single chain fab fragments Grant 9,382,323 - Brinkmann , et al. July 5, 2 | 2016-07-05 |
Promoter App 20160083735 - Klein; Christian ;   et al. | 2016-03-24 |
Use of an amino acid auxotrophy cured prokaryotic strain for the recombinant production of a polypeptide App 20150376674 - Kopetzki; Erhard ;   et al. | 2015-12-31 |
Method For The Expression Of Polypeptides Using Modified Nucleic Acids App 20150246961 - KLOSTERMANN; Stefan ;   et al. | 2015-09-03 |
Method For Selection And Production Of Tailor-made Highly Selective And Multi-specific Targeting Entities Containing At Least Two Different Binding Entities And Uses Thereof App 20150232561 - Fenn; Sebastian ;   et al. | 2015-08-20 |
Method For Making Antibody Fc-region Conjugates Comprising At Least One Binding Entity That Specifically Binds To A Target And Uses Thereof App 20150232541 - FENN; SEBASTIAN ;   et al. | 2015-08-20 |
Method For The Selection And Production Of Tailor-made, Selective And Multi-specific Therapeutic Molecules Comprising At Least Two Different Targeting Entities And Uses Thereof App 20150232560 - HEINDL; DIETER ;   et al. | 2015-08-20 |
Promoter Grant 9,080,183 - Klein , et al. July 14, 2 | 2015-07-14 |
METHOD FOR REDUCTION OF 1->3 READING FRAME SHIFTS App 20150064746 - Grossmann; Adelbert ;   et al. | 2015-03-05 |
METHOD FOR REDUCTION OF 1->2 READING FRAME SHIFTS App 20150056656 - Grossmann; Adelbert ;   et al. | 2015-02-26 |
Protein Expression From Multiple Nucleic Acids App 20140335609 - GOEPFERT; ULRICH ;   et al. | 2014-11-13 |
Prokaryotic expression construct Grant 8,877,895 - Grossmann , et al. November 4, 2 | 2014-11-04 |
Rapid Method For Cloning And Expression Of Cognate Antibody Variable Region Gene Segments App 20140302559 - Hoege; Simone ;   et al. | 2014-10-09 |
Protein expression from multiple nucleic acids Grant 8,771,988 - Goepfert , et al. July 8, 2 | 2014-07-08 |
Incretin Receptor Ligand Polypeptide Fc-Region Fusion Polypeptides And Conjugates With Altered Fc-Effector Function App 20140051834 - HOFFMAN; Eike ;   et al. | 2014-02-20 |
Serpin-finger Fusion Polypeptide App 20140045742 - Engh; Richard ;   et al. | 2014-02-13 |
Recombinant Fc-fusion Protein Of The Fifth Fibronectin Type Iii Domain Of Dcc App 20130336972 - Klein; Christian ;   et al. | 2013-12-19 |
Anti-mhc Antibody Anti Viral Cytokine Fusion Protein App 20130266565 - Jenewein; Stefan ;   et al. | 2013-10-10 |
Polypeptide producing cells Grant 8,541,204 - Endl , et al. September 24, 2 | 2013-09-24 |
Methods of inhibiting the binding of P-selectin to PSGL-1 with anti-P-selectin antibodies Grant RE44,389 - Graus , et al. July 23, 2 | 2013-07-23 |
Nucleic acid molecules encoding anti-P-selectin antibodies Grant RE44,359 - Graus , et al. July 9, 2 | 2013-07-09 |
Polypeptide Producing Cells App 20130109058 - Endl; Josef ;   et al. | 2013-05-02 |
Polypeptide producing cells Grant 8,354,516 - Endl , et al. January 15, 2 | 2013-01-15 |
Glycosylated Repeat-motif-molecule Conjugates App 20120309940 - FISCHER; STEPHAN ;   et al. | 2012-12-06 |
Heavy chain mutant leading to improved immunoglobulin production Grant 8,314,225 - Goepfert , et al. November 20, 2 | 2012-11-20 |
Method and Constructs for the pH Dependent Passage of the Blood-brain-barrier App 20120282176 - Bohrmann; Bernd ;   et al. | 2012-11-08 |
Prokaryotic Expression Construct App 20120214200 - Grossmann; Adelbert ;   et al. | 2012-08-23 |
Anti-P-selectin antibodies Grant RE43,568 - Graus , et al. August 7, 2 | 2012-08-07 |
Bispecific Antibodies App 20110293613 - BRINKMANN; ULRICH ;   et al. | 2011-12-01 |
Cleavage of precursors of insulins by a variant of trypsin Grant 7,981,635 - Zocher , et al. July 19, 2 | 2011-07-19 |
Conjugate Of An Antibody Against Ccr5 And An Antifusogenic Peptide App 20110165182 - Brandt; Michael ;   et al. | 2011-07-07 |
Conjugate of an antibody against CCR5 and an antifusogenic peptide Grant 7,951,920 - Brandt , et al. May 31, 2 | 2011-05-31 |
Protein expression in rodent cells Grant 7,892,790 - Goepfert , et al. February 22, 2 | 2011-02-22 |
Methods of inhibiting the binding of P-selectin to PSGL-1 with anti-P-selectin antibodies Grant 7,824,684 - Graus , et al. November 2, 2 | 2010-11-02 |
Multispecific Antibodies Comprising Full Length Antibodies And Single Chain Fab Fragments App 20100256338 - Brinkmann; Ulrich ;   et al. | 2010-10-07 |
Method for the recombinant expression of a polypeptide Grant 7,807,409 - Kopetzki October 5, 2 | 2010-10-05 |
Protein Expression From Multiple Nucleic Acids App 20100249379 - Goepfert; Ulrich ;   et al. | 2010-09-30 |
Cho-k1 Cell Line App 20100221781 - Kopetzki; Erhard ;   et al. | 2010-09-02 |
Methods Of Inhibiting The Binding Of P-selectin To Psgl-1 App 20100209423 - GRAUS; YVO ;   et al. | 2010-08-19 |
Cleavage Of Precursors Of Insulins By A Variant Of Trypsin App 20100196953 - Geipel; Frank ;   et al. | 2010-08-05 |
Immunoglobulin Production App 20100184144 - Goepfert; Ulrich ;   et al. | 2010-07-22 |
Cho Cell App 20100178672 - DeLange; Robert ;   et al. | 2010-07-15 |
Nucleic acid molecules encoding anti-P-selectin antibodies Grant 7,754,867 - Graus , et al. July 13, 2 | 2010-07-13 |
Promoter App 20100159489 - Klein; Christian ;   et al. | 2010-06-24 |
Protein Expression in Rodent Cells App 20100021965 - Goepfert; Ulrich ;   et al. | 2010-01-28 |
Polypeptide Producing Cells App 20090311725 - Endl; Josef ;   et al. | 2009-12-17 |
Anti-p-selectin Antibodies App 20090311779 - Graus; Yvo ;   et al. | 2009-12-17 |
Antibodies Against Insulin-like Growth Factor I Receptor And Uses Thereof App 20090275126 - Graus; Yvo ;   et al. | 2009-11-05 |
Antibody selection method against IGF-IR Grant 7,579,157 - Graus , et al. August 25, 2 | 2009-08-25 |
Antibodies against insulin-like growth factor I receptor and uses thereof Grant 7,572,897 - Graus , et al. August 11, 2 | 2009-08-11 |
Anti-P-selectin antibodies Grant 7,563,441 - Graus , et al. July 21, 2 | 2009-07-21 |
Conjugate of an antibody against CCR5 and an antifusogenic peptide App 20090028881 - Brandt; Michael ;   et al. | 2009-01-29 |
Conjugate of an antibody against CD4 and antifusogenic peptides App 20090022720 - Fischer; Stephan ;   et al. | 2009-01-22 |
Antibodies Against Insulin-like Growth Factor I Receptor And Uses Thereof App 20080132686 - Graus; Yvo ;   et al. | 2008-06-05 |
Antibodies against insulin-like growth factor 1 receptor and uses thereof Grant 7,378,503 - Graus , et al. May 27, 2 | 2008-05-27 |
Peptide-immunoglobulin-conjugate App 20070148180 - Fischer; Stephan ;   et al. | 2007-06-28 |
Method for the recombinant expression of a polypeptide App 20070117185 - Kopetzki; Erhard | 2007-05-24 |
Method for recombinant production of polypeptides Grant 7,034,119 - Gruenbeck , et al. April 25, 2 | 2006-04-25 |
Anti-P-selectin antibodies App 20050226876 - Graus, Yvo ;   et al. | 2005-10-13 |
Methods for the recombinant production of antifusogenic peptides App 20050191729 - Kaczmarek, Alexandra ;   et al. | 2005-09-01 |
Conjugates of the c domain of human gelatinase a and polyethylene glycol, methods of purification and uses thereof App 20050153416 - Dimoudis, Nikolaos ;   et al. | 2005-07-14 |
Antibodies against insulin-like growth factor 1 receptor and uses thereof App 20050008642 - Graus, Yvo ;   et al. | 2005-01-13 |
Method for recombinant production of polypeptides App 20050003485 - Gruenbeck, Rainer ;   et al. | 2005-01-06 |
Antibodies against insulin-like growth factor 1 receptor and uses thereof App 20040228859 - Graus, Yvo ;   et al. | 2004-11-18 |
Chimeric serine proteases Grant 6,660,492 - Bode , et al. December 9, 2 | 2003-12-09 |
Autocatalytically activatable zymogenic precursors of proteases and their use App 20030207402 - Kopetzki, Erhard ;   et al. | 2003-11-06 |
Recombinant inactive core streptavidin mutants Grant 6,312,916 - Kopetzki , et al. November 6, 2 | 2001-11-06 |
Host-vector system Grant 6,291,245 - Kopetzki , et al. September 18, 2 | 2001-09-18 |
Process for the production of peptides by way of streptavidin fusion proteins Grant 6,136,564 - Kopetzki October 24, 2 | 2000-10-24 |
Electrochemical sensor containing an enzyme linked to binding molecules bound to a noble metal surface Grant 5,834,224 - Ruger , et al. November 10, 1 | 1998-11-10 |
Recombinant core streptavidin Grant 5,672,691 - Kopetzki , et al. September 30, 1 | 1997-09-30 |
Process for the production of proteins or protein-containing gene products Grant 5,179,003 - Wolf , et al. January 12, 1 | 1993-01-12 |