Patent | Date |
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Combinatorial Adenine and Cytosine DNA Base Editors App 20220290121 - Joung; J. Keith ;   et al. | 2022-09-15 |
Base Editors With Improved Precision And Specificity App 20220275356 - Joung; J. Keith ;   et al. | 2022-09-01 |
Engineered Human-endogenous Virus-like Particles And Methods Of Use Thereof For Delivery To Cells App 20220259617 - Joung; J. Keith ;   et al. | 2022-08-18 |
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity App 20220169998 - Joung; J. Keith ;   et al. | 2022-06-02 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20220145275 - Joung; J. Keith ;   et al. | 2022-05-12 |
Base editors with improved precision and specificity Grant 11,326,157 - Joung , et al. May 10, 2 | 2022-05-10 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 11,286,468 - Joung , et al. March 29, 2 | 2022-03-29 |
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci App 20220090145 - Joung; J. Keith ;   et al. | 2022-03-24 |
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1) App 20220025347 - Joung; J. Keith ;   et al. | 2022-01-27 |
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1) App 20220017883 - Joung; J. Keith ;   et al. | 2022-01-20 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 11,220,678 - Joung , et al. January 11, 2 | 2022-01-11 |
Tunneling Nanotube Cells And Methods Of Use Thereof For Delivery Of Biomolecules App 20220002718 - Joung; J. Keith ;   et al. | 2022-01-06 |
Selective Curbing of Unwanted RNA Editing (SECURE) DNA Base Editor Variants App 20210395730 - Grunewald; Julian ;   et al. | 2021-12-23 |
Engineered CRISPR-Cas9 Nucleases App 20210355465 - Joung; J. Keith ;   et al. | 2021-11-18 |
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1) Grant 11,168,313 - Joung , et al. November 9, 2 | 2021-11-09 |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci Grant 11,168,338 - Joung , et al. November 9, 2 | 2021-11-09 |
Inducible, Tunable, and Multiplex Human Gene Regulation Using CRISPR-Cpf1 App 20210309701 - Tak; Yu Gyoung ;   et al. | 2021-10-07 |
Methods For Increasing Efficiency Of Nuclease-induced Homology-directed Repair App 20210292795 - JOUNG; J. Keith ;   et al. | 2021-09-23 |
Variants of CPF1 (CAS12a) With Altered PAM Specificity App 20210269788 - Joung; J. Keith ;   et al. | 2021-09-02 |
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing Grant 11,098,326 - Joung , et al. August 24, 2 | 2021-08-24 |
Engineered CRISPR-Cas9 nucleases Grant 11,060,078 - Joung , et al. July 13, 2 | 2021-07-13 |
CCCTC-binding factor variants Grant 11,041,155 - Joung , et al. June 22, 2 | 2021-06-22 |
Full interrogation of nuclease DSBs and sequencing (FIND-seq) Grant 11,028,429 - Joung , et al. June 8, 2 | 2021-06-08 |
Methods for increasing efficiency of nuclease-induced homology-directed repair Grant 11,021,718 - Joung , et al. June 1, 2 | 2021-06-01 |
TAL-Tet1 Fusion Proteins and Methods of Use Thereof App 20210155907 - Joung; J. Keith ;   et al. | 2021-05-27 |
Highly Sensitive In Vitro Assays To Define Substrate Preferences And Sites Of Nucleic-acid Binding, Modifying, And Cleaving Agents App 20210155984 - Joung; J. Keith ;   et al. | 2021-05-27 |
Increasing Specificity for RNA-Guided Genome Editing App 20210130850 - Joung; J. Keith ;   et al. | 2021-05-06 |
CCCTC-Binding Factor Variants App 20210102213 - Cottman; Rebecca Tayler ;   et al. | 2021-04-08 |
Highly Sensitive In Vitro Assays To Define Substrate Preferences And Sites Of Nucleic-acid Binding, Modifying, And Cleaving Agents App 20210071248 - Joung; J. Keith ;   et al. | 2021-03-11 |
TAL-Tet1 fusion proteins and methods of use thereof Grant 10,894,950 - Joung , et al. January 19, 2 | 2021-01-19 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20200399620 - Joung; J. Keith ;   et al. | 2020-12-24 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20200399621 - Joung; J. Keith ;   et al. | 2020-12-24 |
Increasing specificity for RNA-guided genome editing Grant 10,844,403 - Joung , et al. November 24, 2 | 2020-11-24 |
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci App 20200354704 - Joung; J. Keith ;   et al. | 2020-11-12 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 10,808,233 - Joung , et al. October 20, 2 | 2020-10-20 |
Adenine Dna Base Editor Variants With Reduced Off-target Rna Editing App 20200308571 - Joung; J. Keith ;   et al. | 2020-10-01 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 10,767,168 - Joung , et al. Sep | 2020-09-08 |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci Grant 10,760,064 - Joung , et al. Sep | 2020-09-01 |
Comprehensive in vitro reporting of cleavage events by sequencing (CIRCLE-seq) Grant 10,738,303 - Joung , et al. A | 2020-08-11 |
Targetable 3`-Overhang Nuclease Fusion Proteins App 20200248156 - Kind Code | 2020-08-06 |
Tale transcriptional activators Grant 10,731,167 - Joung , et al. | 2020-08-04 |
Methods for Detecting Site-Specific and Spurious Genomic Deamination Induced by Base Editing Technologies App 20200239930 - Joung; J. Keith ;   et al. | 2020-07-30 |
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing App 20200224222 - Joung; J. Keith ;   et al. | 2020-07-16 |
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing (GUIDE-Seq) App 20200199665 - Joung; J. Keith ;   et al. | 2020-06-25 |
Tale transcriptional activators Grant 10,676,749 - Joung , et al. | 2020-06-09 |
Epigenetically Regulated Site-Specific Nucleases App 20200172899 - Joung; J. Keith ;   et al. | 2020-06-04 |
Using Split Deaminases To Limit Unwanted Off-target Base Editor Deamination App 20200172895 - Joung; J. Keith ;   et al. | 2020-06-04 |
Base Editors With Improved Precision And Specificity App 20200172885 - JOUNG; J. Keith ;   et al. | 2020-06-04 |
Multiplex Guide RNAS App 20200165587 - Tsai; Shengdar ;   et al. | 2020-05-28 |
Engineered CRISPR-Cas9 Nucleases App 20200149024 - Joung; J. Keith ;   et al. | 2020-05-14 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20200149023 - Joung; J. Keith ;   et al. | 2020-05-14 |
Engineered CRISPR-Cas9 Nucleases App 20200140835 - Joung; J. Keith ;   et al. | 2020-05-07 |
Bipartite Base Editor (bbe) Architectures And Type-ii-c-cas9 Zinc Finger Editing App 20200140842 - Joung; J. Keith ;   et al. | 2020-05-07 |
Engineered CRISPR-Cas9 nucleases Grant 10,633,642 - Joung , et al. | 2020-04-28 |
Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing App 20200071730 - Joung; J. Keith ;   et al. | 2020-03-05 |
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing Grant 10,544,433 - Joung , et al. Ja | 2020-01-28 |
Highly Sensitive In Vitro Assays To Define Substrate Preferences And Sites Of Nucleic-acid Binding, Modifying, And Cleaving Agen App 20200010889 - Joung; J. Keith ;   et al. | 2020-01-09 |
Multiplex guide RNAs Grant 10,526,589 - Tsai , et al. J | 2020-01-07 |
Engineered CRISPR-Cas9 nucleases Grant 10,526,591 - Joung , et al. J | 2020-01-07 |
CCCTC-Binding Factor Variants App 20190382767 - Joung; J. Keith ;   et al. | 2019-12-19 |
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci App 20190376090 - Joung; J. Keith ;   et al. | 2019-12-12 |
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq) Grant 10,501,794 - Joung , et al. Dec | 2019-12-10 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 10,479,982 - Joung , et al. Nov | 2019-11-19 |
Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing Grant 10,415,059 - Joung , et al. Sept | 2019-09-17 |
RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic loci Grant 10,378,027 - Joung , et al. A | 2019-08-13 |
Methods of Transcription Activator Like Effector Assembly App 20190177374 - Joung; J. Keith ;   et al. | 2019-06-13 |
Methods of transcription activator like effector assembly Grant 10,273,271 - Joung , et al. | 2019-04-30 |
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity App 20190106687 - Joung; J. Keith ;   et al. | 2019-04-11 |
Engineered CRISPR-Cas9 Nucleases App 20190071657 - Joung; J. Keith ;   et al. | 2019-03-07 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 10,202,589 - Joung , et al. Feb | 2019-02-12 |
Variants of CPF1 (CAS12a) With Altered PAM Specificity App 20190010481 - Joung; J. Keith ;   et al. | 2019-01-10 |
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing App 20180340189 - Joung; J. Keith ;   et al. | 2018-11-29 |
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing Grant 10,138,476 - Joung , et al. Nov | 2018-11-27 |
Synthetic transcriptional and epigenetic regulators based on engineered, orthogonal zinc finger proteins Grant 10,138,493 - Khalil , et al. Nov | 2018-11-27 |
Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing Grant 10,119,133 - Joung , et al. November 6, 2 | 2018-11-06 |
Engineered CRISPR-Cas9 nucleases Grant 10,093,910 - Joung , et al. October 9, 2 | 2018-10-09 |
Engineered CRISPR-Cas9 Nucleases with Altered PAM Specificity App 20180282714 - Joung; J. Keith ;   et al. | 2018-10-04 |
Full Interrogation of Nuclease DSBs and Sequencing (FIND-seq) App 20180265920 - Joung; J. Keith ;   et al. | 2018-09-20 |
Comprehensive In vitro Reporting of Cleavage Events by Sequencing (CIRCLE-seq) App 20180245071 - Joung; J. Keith ;   et al. | 2018-08-30 |
Methods For Increasing Efficiency Of Nuclease-induced Homology-directed Repair App 20180230494 - JOUNG; J. Keith ;   et al. | 2018-08-16 |
Engineered CRISPR-Cas9 Nucleases App 20180216088 - Joung; J. Keith ;   et al. | 2018-08-02 |
Increasing Specificity for RNA-Guided Genome Editing App 20180208921 - Joung; J. Keith ;   et al. | 2018-07-26 |
TAL-Tet1 Fusion Proteins and Methods of Use Thereof App 20180187168 - Joung; J. Keith ;   et al. | 2018-07-05 |
Using RNA-guided FokI Nucleases (RFNs) to increase specificity for RNA-Guided Genome Editing Grant 10,011,850 - Joung , et al. July 3, 2 | 2018-07-03 |
Full interrogation of nuclease DSBs and sequencing (find-seq) Grant 9,988,674 - Joung , et al. June 5, 2 | 2018-06-05 |
Engineered CRISPR-Cas9 nucleases with altered PAM specificity Grant 9,944,912 - Joung , et al. April 17, 2 | 2018-04-17 |
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing (GUIDE-Seq) App 20180087104 - Joung; J. Keith ;   et al. | 2018-03-29 |
Engineered CRISPR-Cas9 nucleases Grant 9,926,546 - Joung , et al. March 27, 2 | 2018-03-27 |
Engineered CRISPR-CAS9 nucleases with altered PAM specificity Grant 9,926,545 - Joung , et al. March 27, 2 | 2018-03-27 |
Synthetic Transcriptional And Epigenetic Regulators Based On Engineered, Orthogonal Zinc Finger Proteins App 20180057838 - Khalil; Ahmad S. ;   et al. | 2018-03-01 |
TAL-Tet1 fusion proteins and methods of use thereof Grant 9,890,364 - Joung , et al. February 13, 2 | 2018-02-13 |
Increasing specificity for RNA-guided genome editing Grant 9,885,033 - Joung , et al. February 6, 2 | 2018-02-06 |
Variants of CRISPR from Prevotella and Francisella 1 (Cpf1) App 20180030425 - Joung; J. Keith ;   et al. | 2018-02-01 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20180002681 - Joung; J. Keith ;   et al. | 2018-01-04 |
Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq) Grant 9,850,484 - Joung , et al. December 26, 2 | 2017-12-26 |
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-Seq) Grant 9,822,407 - Joung , et al. November 21, 2 | 2017-11-21 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20170327804 - Joung; J. Keith ;   et al. | 2017-11-16 |
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing App 20170327805 - Joung; J. Keith ;   et al. | 2017-11-16 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20170327806 - Joung; J. Keith ;   et al. | 2017-11-16 |
Engineered CRISPR-CAS9 nucleases with altered PAM specificity Grant 9,752,132 - Joung , et al. September 5, 2 | 2017-09-05 |
Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing App 20170152508 - Joung; J. Keith ;   et al. | 2017-06-01 |
Tale Transcriptional Activators App 20170114347 - Joung; J. Keith ;   et al. | 2017-04-27 |
Comprehensive In Vitro Reporting of Cleavage Events by Sequencing (Circle-SEQ) App 20170088833 - Joung; J. Keith ;   et al. | 2017-03-30 |
Genetic Correction Of Myotonic Dystrophy Type 1 App 20170088819 - VANDENDRIESSCHE; Thierry ;   et al. | 2017-03-30 |
Engineered CRISPR-Cas9 Nucleases App 20170081650 - Joung; J. Keith ;   et al. | 2017-03-23 |
Full Interrogation Of Nuclease Dsbs And Sequencing (find-seq) App 20170073747 - Joung; J. Keith ;   et al. | 2017-03-16 |
Engineered CRISPR-Cas9 Nucleases App 20170058271 - Joung; J. Keith ;   et al. | 2017-03-02 |
Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editing Grant 9,567,604 - Joung , et al. February 14, 2 | 2017-02-14 |
Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editing Grant 9,567,603 - Joung , et al. February 14, 2 | 2017-02-14 |
Engineered CRISPR-Cas9 nucleases Grant 9,512,446 - Joung , et al. December 6, 2 | 2016-12-06 |
Methods of Transcription Activator Like Effector Assembly App 20160318978 - Joung; J. Keith ;   et al. | 2016-11-03 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20160319261 - Joung; J. Keith ;   et al. | 2016-11-03 |
Multiplex Guide Rnas App 20160319281 - Tsai; Shengdar ;   et al. | 2016-11-03 |
Engineered CRISPR-Cas9 nucleases with Altered PAM Specificity App 20160319260 - Joung; J. Keith ;   et al. | 2016-11-03 |
Engineered CRISPR-CAS9 Nucleases with Altered PAM Specificity App 20160312199 - Joung; J. Keith ;   et al. | 2016-10-27 |
Engineered CRISPR-CAS9 NUCLEASES WITH ALTERED PAM SPECIFICITY App 20160312198 - Joung; J. Keith ;   et al. | 2016-10-27 |
Genomewide Unbiased Identification of DSBs Evaluated by Sequencing (GUIDE-Seq) App 20160304950 - Joung; J. Keith ;   et al. | 2016-10-20 |
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing App 20160153003 - JOUNG; J. Keith ;   et al. | 2016-06-02 |
Increasing Specificity for RNA-Guided Genome Editing App 20160024524 - Joung; J. Keith ;   et al. | 2016-01-28 |
Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing App 20160024523 - Joung; J. Keith ;   et al. | 2016-01-28 |
RNA-Guided Targeting of Genetic and Epigenomic Regulatory Proteins to Specific Genomic Loci App 20160010076 - Joung; J. Keith ;   et al. | 2016-01-14 |
Tale Transcriptional Activators App 20150376626 - Joung; J. Keith ;   et al. | 2015-12-31 |
Rna-guided Targeting Of Genetic And Epigenomic Regulatory Proteins To Specific Genomic Loci App 20140377868 - Joung; J. Keith ;   et al. | 2014-12-25 |
Using RNA-guided FokI Nucleases (RFNs) to Increase Specificity for RNA-Guided Genome Editing App 20140295556 - Joung; J. Keith ;   et al. | 2014-10-02 |
Using Truncated Guide RNAs (tru-gRNAs) to Increase Specificity for RNA-Guided Genome Editing App 20140295557 - Joung; J. Keith ;   et al. | 2014-10-02 |
Methods of Transcription Activator Like Effector Assembly App 20140274812 - Joung; J. Keith ;   et al. | 2014-09-18 |
Methods For Site-specific Genetic Modification In Stem Cells Using Xanthomonas Tal Nucleases (xtn) For The Creation Of Model Organisms App 20140201858 - Ostertag; Eric M. ;   et al. | 2014-07-17 |
TAL-Tet1 Fusion Proteins and Methods of Use Thereof App 20130323220 - Joung; J. Keith ;   et al. | 2013-12-05 |
Engineering Of Zinc Finger Arrays By Context-dependent Assembly App 20120178647 - Joung; J. Keith ;   et al. | 2012-07-12 |
Yeast bacterial two-hybrid system and methods of use thereof Grant 7,919,610 - Serebriiskii , et al. April 5, 2 | 2011-04-05 |
Methods and compositions for interaction trap assays Grant 7,393,318 - Joung , et al. July 1, 2 | 2008-07-01 |
Yeast Bacterial Two-Hybrid System And Methods Of Use Thereof App 20080118919 - Serebriiskii; Ilya G. ;   et al. | 2008-05-22 |
Methods and compositions for interaction trap assays Grant 7,297,491 - Joung , et al. November 20, 2 | 2007-11-20 |
Context sensitive paralell optimization of zinc finger dna binding domains App 20070178454 - Joung; J. Keith ;   et al. | 2007-08-02 |
Methods for producing zinc finger proteins that bind to extended dna target sequences App 20060246440 - Joung; J. Keith | 2006-11-02 |
Methods and compositions for interaction trap assays Grant 7,029,847 - Joung , et al. April 18, 2 | 2006-04-18 |
Methods and compositions for interaction trap assays App 20050064477 - Joung, J. Keith ;   et al. | 2005-03-24 |
Methods and compositions for interaction trap assays App 20040146931 - Joung, J. Keith ;   et al. | 2004-07-29 |
Methods and compositions for interaction trap assays App 20030044787 - Joung, J. Keith ;   et al. | 2003-03-06 |
Methods and compositions for interaction trap assays App 20020119498 - Joung, J. Keith ;   et al. | 2002-08-29 |
Intraction trap assay, reagents and uses thereof Grant 5,925,523 - Dove , et al. July 20, 1 | 1999-07-20 |