Patent | Date |
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Protein Tyrosine Phosphatase Inhibitors App 20220251083 - BLAKE; James Francis ;   et al. | 2022-08-11 |
Substituted Pyrazolo[1,5-a]pyrazine Compounds As Ret Kinase Inhibitors App 20220119396 - ANDREWS; Steven W. ;   et al. | 2022-04-21 |
Fused Heterocyclic Compounds As Ret Kinase Inhibitors App 20220112214 - BLAKE; James F. ;   et al. | 2022-04-14 |
Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Grant 11,267,818 - Haas , et al. March 8, 2 | 2022-03-08 |
Process for the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrim- idin-3-yl)-3-hydroxypyrrolidine-1-carboxamide and salts thereof Grant 11,214,571 - Reynolds , et al. January 4, 2 | 2022-01-04 |
Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors Grant 11,168,090 - Andrews , et al. November 9, 2 | 2021-11-09 |
Process for the preparation of pyrazolo[1,5-a]pyrimidines and salts thereof Grant 11,091,486 - Zhao , et al. August 17, 2 | 2021-08-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20210186959 - Andrews; Steven W. ;   et al. | 2021-06-24 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,953,005 - Andrews , et al. March 23, 2 | 2021-03-23 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,889,589 - Allen , et al. January 12, 2 | 2021-01-12 |
Method Of Treatment Using Substituted Pyrazolo[1,5-a] Pyrimidine Compounds App 20210002287 - Haas; Julia ;   et al. | 2021-01-07 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,881,652 - Andrews , et al. January 5, 2 | 2021-01-05 |
SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS AS RET KINASE INHIBITORS App 20200399279 - BLAKE; James F. ;   et al. | 2020-12-24 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200383966 - ANDREWS; Steven W. ;   et al. | 2020-12-10 |
Substituted Pyrazolyl[4,3-c]pyridine Compounds As Ret Kinase Inhibitors App 20200339579 - WALLS; Shane M. ;   et al. | 2020-10-29 |
Substituted Pyrrolo[2,3-d]pyrimidines Compounds As Ret Kinase Inhibitors App 20200339589 - BLAKE; James F. ;   et al. | 2020-10-29 |
Protein Tyrosine Phosphatase Inhibitors App 20200317665 - BLAKE; James F. ;   et al. | 2020-10-08 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20200291026 - Andrews; Steven W. ;   et al. | 2020-09-17 |
Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds Grant 10,774,085 - Haas , et al. Sept | 2020-09-15 |
Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 10,758,542 - Allen , et al. Sep | 2020-09-01 |
PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF App 20200216451 - Zhao; Qian ;   et al. | 2020-07-09 |
Macrocyclic compounds as TRK kinase inhibitors Grant 10,647,730 - Andrews , et al. | 2020-05-12 |
Method of treatment using substituted imidazo[1,2b]pyridazine compounds Grant 10,590,139 - Andrews , et al. | 2020-03-17 |
Crystalline forms Grant 10,584,124 - Metcalf , et al. | 2020-03-10 |
Substituted Pyrazolo[1,5-a]pyrazine Compounds As Ret Kinase Inhibitors App 20200055860 - ANDREWS; Steven W ;   et al. | 2020-02-20 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,555,944 - Andrews , et al. Feb | 2020-02-11 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20200030311 - ANDREWS; Steven W. ;   et al. | 2020-01-30 |
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS App 20190365763 - Allen; Shelley ;   et al. | 2019-12-05 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20190359597 - Allen; Shelley ;   et al. | 2019-11-28 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,441,581 - Andrews , et al. Oc | 2019-10-15 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20190270749 - Allen; Shelley ;   et al. | 2019-09-05 |
Crystalline Forms App 20190263811 - Metcalf; Andrew T. ;   et al. | 2019-08-29 |
Formulations Of A Macrocyclic Trk Kinase Inhibitor App 20190247398 - Zhao; Qian ;   et al. | 2019-08-15 |
Process For The Preparation Of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrim- Idin-3-yl)-3-hydroxypy App 20190218222 - Reynolds; Mark ;   et al. | 2019-07-18 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain Grant 10,351,575 - Allen , et al. July 16, 2 | 2019-07-16 |
Method Of Treatment Using Substituted Pyrazolo[1,5-a] Pyrimidine Compounds App 20190211017 - Haas; Julia ;   et al. | 2019-07-11 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190183886 - Andrews; Steven W. ;   et al. | 2019-06-20 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 10,323,022 - Allen , et al. | 2019-06-18 |
Method of Treatment Using Substituted Imidazo[1,2b]Pyridazine Compounds App 20190169193 - Andrews; Steven W. ;   et al. | 2019-06-06 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127375 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127373 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20190127374 - Andrews; Steven W. ;   et al. | 2019-05-02 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 10,251,889 - Allen , et al. | 2019-04-09 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20190031684 - Andrews; Steven W. ;   et al. | 2019-01-31 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,851 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,174,028 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,174,027 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,172,845 - Andrews , et al. J | 2019-01-08 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,144,734 - Andrews , et al. De | 2018-12-04 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,137,124 - Andrews , et al. November 27, 2 | 2018-11-27 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors Grant 10,138,243 - Andrews , et al. Nov | 2018-11-27 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20180334450 - Allen; Shelley ;   et al. | 2018-11-22 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,112,942 - Andrews , et al. October 30, 2 | 2018-10-30 |
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS App 20180263984 - Allen; Shelley ;   et al. | 2018-09-20 |
Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Grant 10,047,097 - Haas , et al. August 14, 2 | 2018-08-14 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors Grant 10,023,570 - Andrews , et al. July 17, 2 | 2018-07-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180186790 - Andrews; Steven W. ;   et al. | 2018-07-05 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180186791 - Andrews; Steven W. ;   et al. | 2018-07-05 |
Method of treatment using substituted imidazo[1,2b]pyridazine compounds Grant 10,011,604 - Andrews , et al. July 3, 2 | 2018-07-03 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180179203 - Andrews; Steven W. ;   et al. | 2018-06-28 |
Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Grant 10,005,783 - Haas , et al. June 26, 2 | 2018-06-26 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180148445 - Andrews; Steven W. ;   et al. | 2018-05-31 |
Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,981,959 - Brandhuber , et al. May 29, 2 | 2018-05-29 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134703 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133213 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133200 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180133207 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20180134702 - Andrews; Steven W. ;   et al. | 2018-05-17 |
Method Of Treatment Using Substituted Pyrazolo[1,5-a] Pyrimidine Compounds App 20180127427 - Haas; Julia ;   et al. | 2018-05-10 |
Macrocyclic compounds as TRK kinase inhibitors Grant 9,902,741 - Andrews , et al. February 27, 2 | 2018-02-27 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 9,878,997 - Allen , et al. January 30, 2 | 2018-01-30 |
Macrocyclic compounds as TRK kinase inhibitors Grant 9,840,519 - Andrews , et al. December 12, 2 | 2017-12-12 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,828,360 - Allen , et al. November 28, 2 | 2017-11-28 |
Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors Grant 9,809,578 - Brandhuber , et al. November 7, 2 | 2017-11-07 |
Method of treatment using substituted imidazo[1,2b]pyridazine compounds Grant 9,795,611 - Andrews , et al. October 24, 2 | 2017-10-24 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 9,796,724 - Allen , et al. October 24, 2 | 2017-10-24 |
Method of treatment using substituted imidazo[1,2b]pyridazine compounds Grant 9,796,723 - Andrews , et al. October 24, 2 | 2017-10-24 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,790,178 - Allen , et al. October 17, 2 | 2017-10-17 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 9,782,415 - Allen , et al. October 10, 2 | 2017-10-10 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170283435 - Andrews; Steven W. ;   et al. | 2017-10-05 |
Macrocyclic compounds as Trk kinase inhibitors Grant 9,750,744 - Andrews , et al. September 5, 2 | 2017-09-05 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20170217936 - Allen; Shelley ;   et al. | 2017-08-03 |
Macrocyclic compounds as Trk kinase inhibitors Grant 9,718,822 - Andrews , et al. August 1, 2 | 2017-08-01 |
Substituted pyrazolo [1,5-A] pyrimidine compounds as TRK kinase inhibitors Grant 9,682,979 - Allen , et al. June 20, 2 | 2017-06-20 |
Method of treatment using substituted pyrazolo[1,5-A] pyrimidine compounds Grant 9,676,783 - Haas , et al. June 13, 2 | 2017-06-13 |
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS App 20170119770 - Allen; Shelley ;   et al. | 2017-05-04 |
Method of Treatment Using Substituted Imidazo[1,2b]Pyridazine Compounds App 20170112849 - Andrews; Steven W. ;   et al. | 2017-04-27 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170112842 - Andrews; Steven W. ;   et al. | 2017-04-27 |
Method of Treatment Using Substituted Imidazo[1,2b]Pyridazine Compounds App 20170114068 - Andrews; Steven W. ;   et al. | 2017-04-27 |
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS App 20170114069 - Allen; Shelley ;   et al. | 2017-04-27 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170114059 - Andrews; Steven W. ;   et al. | 2017-04-27 |
Method Of Treatment Using Substituted Pyrazolo[1,5-a] Pyrimidine Compounds App 20170114067 - Haas; Julia ;   et al. | 2017-04-27 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20170107232 - Andrews; Steven W. ;   et al. | 2017-04-20 |
Substituted Pyrazolo[1,5-a]pyridine Compounds As Ret Kinase Inhibitors App 20170096425 - Andrews; Steven W. ;   et al. | 2017-04-06 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors Grant 9,562,055 - Allen , et al. February 7, 2 | 2017-02-07 |
N-bicyclic aryl,N'-pyrazolyl urea, thiourea, guanidine cyanoguanidine compounds as TrkA kinase inhibitors Grant 9,546,156 - Allen , et al. January 17, 2 | 2017-01-17 |
Bicyclic Urea, Thiourea, Guanidine And Cyanoguanidine Compounds Useful For The Treatment Of Pain App 20160355521 - Allen; Shelley ;   et al. | 2016-12-08 |
Macrocyclic compounds as trk kinase inhibitors Grant 9,493,476 - Andrews , et al. November 15, 2 | 2016-11-15 |
Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160297758 - Allen; Shelley ;   et al. | 2016-10-13 |
Pyrrolidinyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160297796 - Allen; Shelley ;   et al. | 2016-10-13 |
N-bicyclic Aryl,n'-pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280681 - Allen; Shelley ;   et al. | 2016-09-29 |
Pyrazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280690 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
Thiazolyl And Oxazolyl Urea, Thiourea, Guanidine And Cyanoguanidine Compounds As Trka Kinase Inhibitors App 20160280702 - Brandhuber; Barbara J. ;   et al. | 2016-09-29 |
Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds Grant 9,447,104 - Haas , et al. September 20, 2 | 2016-09-20 |
Method of Treatment Using Substituted Imidazo[1,2b]Pyridazine Compounds App 20160251357 - Andrews; Steven W. ;   et al. | 2016-09-01 |
Method Of Treatment Using Substituted Pyrazolo[1,5-a] Pyrimidine Compounds App 20160228441 - Haas; Julia ;   et al. | 2016-08-11 |
Method of treatment using substituted imidazo[1,2B]pyridazine compounds Grant 9,227,975 - Andrews , et al. January 5, 2 | 2016-01-05 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20150336970 - Andrews; Steven Wade ;   et al. | 2015-11-26 |
Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds Grant 9,127,013 - Haas , et al. September 8, 2 | 2015-09-08 |
Pyrrolidinyl Urea, Pyrrolidinyl Thiourea And Pyrrolidinyl Guanidine Compounds As Trka Kinase Inhibitors App 20150166564 - Allen; Shelley ;   et al. | 2015-06-18 |
METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-a] PYRIMIDINE COMPOUNDS App 20150133429 - Haas; Julia ;   et al. | 2015-05-14 |
Substituted Pyrazolo [1,5-A] Pyrimidine Compounds as TRK Kinase Inhibitors App 20150031667 - Allen; Shelley ;   et al. | 2015-01-29 |
Macrocyclic compounds as Trk kinase inhibitors Grant 8,933,084 - Andrews , et al. January 13, 2 | 2015-01-13 |
METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS App 20150005499 - Haas; Julia ;   et al. | 2015-01-01 |
Method of treatment using substituted pyrazolo[1,5-a]pyrimidine compounds Grant 8,865,698 - Haas , et al. October 21, 2 | 2014-10-21 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 8,791,123 - Allen , et al. July 29, 2 | 2014-07-29 |
METHOD OF TREATMENT USING SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS App 20140194403 - Haas; Julia ;   et al. | 2014-07-10 |
Method Of Treatment Using Substituted Imidazo[1,2b]pyridazine Compounds App 20130217662 - Andrews; Steven W. ;   et al. | 2013-08-22 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors Grant 8,513,263 - Haas , et al. August 20, 2 | 2013-08-20 |
Macrocyclic Compounds As Trk Kinase Inhibitors App 20130203776 - Andrews; Steven Wade ;   et al. | 2013-08-08 |
Substituted imidazo[1,2b]pyridazine compounds as Trk kinase inhibitors Grant 8,450,322 - Andrews , et al. May 28, 2 | 2013-05-28 |
Macrocyclic inhibitors of hepatitis C virus replication Grant 8,299,021 - Blatt , et al. October 30, 2 | 2012-10-30 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20120208995 - Blatt; Lawrence M. ;   et al. | 2012-08-16 |
SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS App 20120108568 - Allen; Shelley ;   et al. | 2012-05-03 |
Substituted Pyrazolo[1,5-a]Pyrimidine Compounds as TRK Kinase Inhibitors App 20110195948 - Haas; Julia ;   et al. | 2011-08-11 |
SUBSTITUTED IMIDAZO[1,2b]PYRIDAZINE COMPOUNDS AS TRK KINASE INHIBITORS App 20110166122 - Andrews; Steven W. ;   et al. | 2011-07-07 |
Peptide inhibitors of hepatitis C virus replication Grant 7,932,277 - Seiwert , et al. April 26, 2 | 2011-04-26 |
Macrocyclic inhibitors of hepatitis C virus replication Grant 7,829,665 - Blatt , et al. November 9, 2 | 2010-11-09 |
Novel Peptide Inhibitors Of Hepatitis C Virus Replication App 20090297476 - SEIWERT; SCOTT ;   et al. | 2009-12-03 |
Macrocyclic Compounds As Inhibitors Of Viral Replication App 20090286843 - BLATT; LAWRENCE M. ;   et al. | 2009-11-19 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20090169510 - Blatt; Lawrence M ;   et al. | 2009-07-02 |
Novel Macrocyclic Inhibitors Of Hepatitis C Virus Replication App 20090155209 - BLATT; LAWRENCE M. ;   et al. | 2009-06-18 |
Novel Macrocyclic Inhibitors of Hepatitis C Virus Replication App 20090148407 - Blatt; Lawrence M. ;   et al. | 2009-06-11 |
Macrocyclic Compounds As Inhibitors Of Viral Replication App 20090111982 - Blatt; Lawrence M. ;   et al. | 2009-04-30 |
Macrocyclic Compounds As Inhibitors Of Viral Replication App 20090111969 - Blatt; Lawrence M. ;   et al. | 2009-04-30 |
Macrocyclic Compounds As Inhibitors Of Viral Replication App 20090105471 - Blatt; Lawrence M. ;   et al. | 2009-04-23 |
Macrocyclic compounds as inhibitors of viral replication Grant 7,491,794 - Blatt , et al. February 17, 2 | 2009-02-17 |
Novel macrocyclic inhibitors of hepatitis C virus replication App 20070054842 - Blatt; Lawrence M. ;   et al. | 2007-03-08 |
Macrocyclic compounds as inhibitors of viral replication App 20050267018 - Blatt, Lawrence M. ;   et al. | 2005-12-01 |