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Use of 2-carboxamide cycloamino urea derivatives in the treatment of EGFR dependent diseases or diseases that have acquired resi App 20200022967 - BRACHMANN; Saskia Maria ;   et al. | 2020-01-23 |
Use of 2-carboxamide cycloamino urea derivatives in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members App 20180325883 - Brachmann; Saskia Maria ;   et al. | 2018-11-15 |
Combination Of A Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20180133226 - Garcia-Echeverria; Carlos ;   et al. | 2018-05-17 |
Combination Of Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20180085362 - Fritsch; Christine ;   et al. | 2018-03-29 |
Combination Of Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20170095463 - Fritsch; Christine ;   et al. | 2017-04-06 |
Hsp90 Inhibitor Combinations App 20170049781 - Garcia-Echeverria; Carlos ;   et al. | 2017-02-23 |
Pharmaceutical Combinations Comprising A Pyrido [4,3-d] Pyrimidine Derived Hsp90-inhibitor And A Her2 Inhibitor App 20160346292 - Garcia-Echeverria; Carlos ;   et al. | 2016-12-01 |
Isoxazole Compound For The Treatment Of Cancer App 20160220576 - Chene; Patrick ;   et al. | 2016-08-04 |
Imidazoquinolines as dual lipid kinase and mTOR inhibitors Grant 9,370,508 - Garcia-Echeverria , et al. June 21, 2 | 2016-06-21 |
Combination Of A Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20160136175 - Garcia-Echeverria; Carlos ;   et al. | 2016-05-19 |
Isoxazole Compound For The Treatment Of Cancer App 20160045513 - Chene; Patrick ;   et al. | 2016-02-18 |
Anti-tumoral Composition Comprising A Pi3kbeta-selective Inhibitor And A Pi3kalpha-selective Inhibitor App 20160030440 - BONNEVAUX; Helene ;   et al. | 2016-02-04 |
Anti-tumoral Composition Comprising A Pi3kbeta Inhibitor And A Raf Inhibitor, To Overcome Cancer Cells Resistance App 20160030438 - BONNEVAUX; Helene ;   et al. | 2016-02-04 |
Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of RAS/RAF/MEK pathway Grant 9,241,939 - Garcia-Echeverria , et al. January 26, 2 | 2016-01-26 |
MEK Mutations Conferring Resistance to MEK Inhibitors App 20150346204 - Garraway; Levi A. ;   et al. | 2015-12-03 |
Use of 2-carboxamide cycloamino urea derivatives in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members App 20150250778 - Brachmann; Saskia Maria ;   et al. | 2015-09-10 |
Pharmaceutical Combinations Comprising A Pyrido [4,3-d] Pyrimidine Derived Hsp90-inhibitor And A Her2 Inhibitor App 20150209362 - Garcia-Echeverria; Carlos ;   et al. | 2015-07-30 |
MEK mutations conferring resistance to MEK inhibitors Grant 9,084,781 - Garraway , et al. July 21, 2 | 2015-07-21 |
Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of RAS/RAF/MEK pathway App 20150105417 - Garcia-Echeverria; Carlos ;   et al. | 2015-04-16 |
Methods And Compositions For Treating Solid Tumors And Other Malignancies App 20150025074 - Buonamici; Silvia ;   et al. | 2015-01-22 |
Pharmaceutical Combinations Comprising A Pyrido [4,3-d] Pyrimidine Derived Hsp90-inhibitor And A Her2 Inhibitor App 20140328834 - Garcia-Echeverria; Carlos ;   et al. | 2014-11-06 |
Isoxazole compound for the treatment of cancer App 20140288075 - Chene; Patrick ;   et al. | 2014-09-25 |
Compositions And Methods For Treating Cancer Using Pi3kb Inhibitor And Mapk Pathway Inhibitor, Including Mek And Raf Inhibitors App 20140275078 - Garcia-Echeverria; Carlos ;   et al. | 2014-09-18 |
Hsp90 inhibitor combinations App 20140242088 - Garcia-Echeverria; Carlos ;   et al. | 2014-08-28 |
Use Of Pyrimidine Derivatives For The Treatment Of Egfr Dependent Diseases Or Diseases That Have Acquired Resistance To Agents That Target Egfr Family Members App 20140161722 - Garcia-Echeverria; Carlos ;   et al. | 2014-06-12 |
Combination Of Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20140066474 - Fritsch; Christine ;   et al. | 2014-03-06 |
Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of RAS/RAF/MEK pathway App 20140057904 - Garcia-Echeverria; Carlos ;   et al. | 2014-02-27 |
Compositions And Methods For Treating Cancer Using Pi3k Inhibitor And Mek Inhibitor App 20140024653 - DEBUSSCHE; Laurent ;   et al. | 2014-01-23 |
Spiro-oxindole MDM2 antagonists Grant 8,629,141 - Wang , et al. January 14, 2 | 2014-01-14 |
Use of 2-carboxamide cycloamino urea derivatives in the treatment of EGFR dependent diseases or diseases that have acquired resistance to agents that target EGFR family members App 20130209461 - Brachmann; Saskia Maria ;   et al. | 2013-08-15 |
1,3-dihydro-imidazo[4,5-c]quinolin-2-ones as lipid kinase inhibitors Grant 8,431,592 - Garcia-Echeverria , et al. April 30, 2 | 2013-04-30 |
Method Of Identification Of Cells That Show Sensitivity To Modulation Of Signaling Mediated By A Fibroblast Growth Factor Receptor Or A Variant Thereof App 20120315648 - Graus Porta; Diana ;   et al. | 2012-12-13 |
Spiro-oxindole Mdm2 Antagonists App 20120289494 - Wang; Shaomeng ;   et al. | 2012-11-15 |
5Imidazoquinolines and Pyrimidine Derivatives as Potent Modulators of VEGF-Driven Angiogenic Processes App 20120282252 - Garcia-Echeverria; Carlos | 2012-11-08 |
Methods And Compositions For Treating Solid Tumors And Other Malignancies App 20120232087 - Buonamici; Silvia ;   et al. | 2012-09-13 |
Pyrimidine derivatives Grant 8,263,590 - Garcia-Echeverria , et al. September 11, 2 | 2012-09-11 |
Pharmaceutical Combinations Comprising A Pyrido [4,3-d] Pyrimidine Derived Hsp90-inhibitor And A Her2 Inhibitor App 20120219550 - Garcia-Echeverria; Carlos ;   et al. | 2012-08-30 |
Isoxazole Compound For The Treatment Of Cancer App 20120214813 - Chene; Patrick ;   et al. | 2012-08-23 |
Imidazoquinolines as lipid kinase inhibitors App 20120207751 - Garcia-Echeverria; Carlos ;   et al. | 2012-08-16 |
Isoxazole Compound For The Treatment Of Cancer App 20120083496 - CHENE; Patrick ;   et al. | 2012-04-05 |
Combination Of (a) A Phosphoinositide 3-kinase Inhibitor And (b) An Antidiabetic Compound For Use In The Treatment Of Proliferative Diseases App 20120059005 - Baselga; Jose ;   et al. | 2012-03-08 |
Mek Mutations Conferring Resistance To Mek Inhibitors App 20120015973 - Garraway; Levi A. ;   et al. | 2012-01-19 |
1,3-Dihydro-imidazo[4,5-c]quinolin-2-ones as Lipid Kinase Inhibitors App 20110251202 - GARCIA-ECHEVERRIA; Carlos ;   et al. | 2011-10-13 |
Pharmaceutical Combinations Comprising A Pyrido [4,3-d] Pyrimidine Derived Hsp90-inhibitor And A Her2 Inhibitor App 20110236379 - Garcia-Echeverria; Carlos ;   et al. | 2011-09-29 |
Pharmaceutical Combination Comprising A Hsp 90 Inhibitor And A Mtor Inhibitor App 20110230444 - Garcia-Echeverria; Carlos ;   et al. | 2011-09-22 |
Hsp90 Inhibitors For Therapeutic Treatment App 20110230499 - Garcia-Echeverria; Carlos ;   et al. | 2011-09-22 |
Pyrimidine Derivatives App 20110201606 - Garcia-Echeverria; Carlos ;   et al. | 2011-08-18 |
1H-imidazo[4,5-c]quinoline derivatives in the treatment of protein kinase dependent diseases Grant 7,998,972 - Garcia-Echeverria , et al. August 16, 2 | 2011-08-16 |
Combination Of A Phosphatidylinositol-3-kinase (pi3k) Inhibitor And A Mtor Inhibitor App 20110195966 - Garcia-Echeverria; Carlos ;   et al. | 2011-08-11 |
1,3-dihydro-imidazo[4,5-C]quinolin-2-ones as lipid kinase inhibitors Grant 7,994,170 - Garcia-Echeverria , et al. August 9, 2 | 2011-08-09 |
2,4-di (phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders Grant 7,964,592 - Garcia-Echeverria , et al. June 21, 2 | 2011-06-21 |
Combination Of (a) A Phosphoinositide 3-kinase Inhibitor And (b) A Modulator Of Ras/raf/mek Pathway App 20110105521 - Garcia-Echeverria; Carlos ;   et al. | 2011-05-05 |
2,4-pyrimidinediamines Useful In The Treatment Of Neoplastic Diseases, Inflammatory And Immune System Disorders App 20110098280 - Garcia-Echeverria; Carlos ;   et al. | 2011-04-28 |
2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders Grant 7,893,074 - Garcia-Echeverria , et al. February 22, 2 | 2011-02-22 |
Use Of Pyrimidine Derivatives For The Treatment Of Egfr Dependent Diseases Or Diseases That Have Acquired Resistance To Agents That Target Egfr Family Members App 20110033453 - Garcia-Echeverria; Carlos ;   et al. | 2011-02-10 |
5Imidazoquinolines and Pyrimidine Derivatives as Potent Modulators of VEGF-Driven Angiogenic Processes App 20110020338 - Garcia-Echeverria; Carlos | 2011-01-27 |
Isoxazole Compound For The Treatment Of Cancer App 20100210650 - Chene; Patrick ;   et al. | 2010-08-19 |
Use Of Imidazoquinolines For The Treatment Of Egfr Dependent Diseases Or Diseases That Have Acquired Resistance To Agents That Target Egfr Family Members App 20100196365 - Garcia-Echeverria; Carlos ;   et al. | 2010-08-05 |
IMIDAZOQUINOLINES AS DUAL LIPID KINASE AND mTOR INHIBITORS App 20100105696 - Garcia-Echeverria; Carlos ;   et al. | 2010-04-29 |
Method Of Identification Of Cells That Show Sensitivity To Modulation Of Signalingh Mediated By Fibroblast Growth Factor Receptor Or A Variant Thereof App 20100075337 - Graus Porta; Diana ;   et al. | 2010-03-25 |
1,3-dihydro-imidazo[4,5-c]quinolin-2-ones As Lipid Kinase Inhibitors App 20100056558 - Garcia-Echeverria; Carlos ;   et al. | 2010-03-04 |
1,3-dihydro-imidazo [4,5-C] quinolin-2-ones as lipid kinase inhibitors Grant 7,667,039 - Garcia-Echeverria , et al. February 23, 2 | 2010-02-23 |
Phenyl-[4-(3-phenyl-1h-pyrazol-4-yl)-pyrimidin-2-yl]-amine derivatives as igf-ir inhibitors App 20090149469 - Garcia-Echeverria; Carlos | 2009-06-11 |
Diaryl Urea Derivatives in the Treatment of Protein Kinase Dependent Diseases App 20080312192 - Bold; Guido ;   et al. | 2008-12-18 |
1H-Imidazoquinoline Derivatives as Prote In Kinase Inhibitors App 20080262021 - Capraro; Hans-Georg ;   et al. | 2008-10-23 |
1,3-Dihydro-Imidazo [4,5-C] Quinolin-2-Ones as Lipid Kinase Inhibitors App 20080194579 - Garcia-Echeverria; Carlos ;   et al. | 2008-08-14 |
2, 4-Pyrimidinediamines Useful In The Treatment Of Neoplastic Diseases, Inflammatory And Immune System Disorders App 20080132504 - Garcia-Echeverria; Carlos ;   et al. | 2008-06-05 |
4-Amino-5-phenyl-7-cyclobutyl-pyrrolo(2,3-d)pyrimidine derivatives Grant 7,326,699 - Capraro , et al. February 5, 2 | 2008-02-05 |
2,4-Di (phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders App 20060247241 - Garcia-Echeverria; Carlos ;   et al. | 2006-11-02 |
2-Amino-3-hydroxy-4-tert-leucyl-amino-5-phenyl-pentanoic acid amide derivatives App 20060205673 - Furet; Pascal ;   et al. | 2006-09-14 |
Inhibitors of the interaction between P53 and MDM2 Grant 7,083,983 - Lane , et al. August 1, 2 | 2006-08-01 |
4-Amino-5-phenyl-7-cyclohexyl-pyrrolo 2,3-d pyrimidine derivatives App 20060058324 - Capraro; Hans-Georg ;   et al. | 2006-03-16 |
1h-imidazo[4,5-c]quinoline derivatives in the treatment of protein kinase dependent diseases App 20050245562 - Garcia-Echeverria, Carlos ;   et al. | 2005-11-03 |
Methods and compositions for treating hyperproliferative conditions App 20050215564 - Stiles, Charles Dean ;   et al. | 2005-09-29 |
Inhibitors of the Interaction between p53 and MDM2 App 20050137137 - Lane, David Philip ;   et al. | 2005-06-23 |
Organic compounds App 20050118598 - Garcia-Echeverria, Carlos ;   et al. | 2005-06-02 |
Use of 2, 4diamino-3-hydroxycarboxylic acid derivatives as proteasome inhibitors App 20050026994 - France, Dennis ;   et al. | 2005-02-03 |
Peptide screen App 20040248194 - Garcia-Echeverria, Carlos ;   et al. | 2004-12-09 |
4-Amino-5-phenyl-7-cyclobutyl-pyrrolo(2,3-d)pyrimidine derivatives App 20040180911 - Capraro, Hans-Georg ;   et al. | 2004-09-16 |
2-Amino-3-hydroxy-4-tert-leucyl-amino-5 phenyl-pentanoic acid amide derivatives App 20030166572 - Furet, Pascal ;   et al. | 2003-09-04 |
Inhibitors Of The Interaction Between P53 And Mdm2 App 20010018511 - LANE, DAVID ;   et al. | 2001-08-30 |