Patent | Date |
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Amplification methods Grant 8,067,177 - Mahoney , et al. November 29, 2 | 2011-11-29 |
Negatively Charged Minor Groove Binders App 20100137614 - Lukhtanov; Eugeny A. ;   et al. | 2010-06-03 |
Compounds and methods for fluorescent labeling Grant 7,601,851 - Lukhtanov , et al. October 13, 2 | 2009-10-13 |
Negatively charged minor groove binders Grant 7,582,739 - Lukhtanov , et al. September 1, 2 | 2009-09-01 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 7,556,923 - Hedgpeth , et al. July 7, 2 | 2009-07-07 |
Method for amplifying target nucleic acid sequences using a primer comprising an AP endonuclease-cleavable linker Grant 7,553,643 - Kutyavin , et al. June 30, 2 | 2009-06-30 |
Compounds and methods for fluorescent labeling Grant 7,541,454 - Lukhtanov June 2, 2 | 2009-06-02 |
Amide-substituted Xanthene Dyes App 20090093612 - Lukhtanov; Eugene | 2009-04-09 |
Method For Generating Target Nucleic Acid Sequences App 20090092967 - Yao; Zuxu ;   et al. | 2009-04-09 |
Single Nucleotide Polymorphism Analysis Of Highly Polymorphic Target Sequences App 20090087922 - Belousov; Yevgeniy ;   et al. | 2009-04-02 |
Hybridization And Mismatch Discrimination Using Oligonucleotides Conjugated To Minor Groove Binders App 20090048427 - HEDGPETH; JOEL ;   et al. | 2009-02-19 |
Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis Grant 7,485,442 - Afonina , et al. February 3, 2 | 2009-02-03 |
Fluorescent Probes For Dna Detection By Hybridization With Improved Sensitivity And Low Background App 20080293586 - Lokhov; Sergey ;   et al. | 2008-11-27 |
Amplification Methods App 20080248474 - MAHONEY; WALT ;   et al. | 2008-10-09 |
Phosphonylated Fluorescent Dyes And Conjugates App 20080207887 - Lukhtanov; Eugeny ;   et al. | 2008-08-28 |
Abasic Site Endonuclease Assay App 20080166782 - Kutyavin; Igor V. ;   et al. | 2008-07-10 |
Fluorescent probes containing 5'-minor groove binder, fluorophore and quenching moieties and methods of use thereof Grant 7,381,818 - Lokhov , et al. June 3, 2 | 2008-06-03 |
T.sub.m leveling compositions Grant 7,368,549 - Dempcy , et al. May 6, 2 | 2008-05-06 |
Single nucleotide polymorphism analysis of highly polymorphic target sequences Grant 7,348,146 - Belousov , et al. March 25, 2 | 2008-03-25 |
Amplification methods Grant 7,319,022 - Mahoney , et al. January 15, 2 | 2008-01-15 |
Hybridization-triggered fluorescent detection of nucleic acids Grant 7,297,495 - Dempcy , et al. November 20, 2 | 2007-11-20 |
Abasic site endonuclease assay Grant 7,252,940 - Kutyavin , et al. August 7, 2 | 2007-08-07 |
Phosphonate fluorescent dyes and conjugates App 20070172832 - Lukhtanov; Eugeny ;   et al. | 2007-07-26 |
Hybridization-triggered fluorescent detection of nucleic acids App 20070166723 - Dempcy; Robert O. ;   et al. | 2007-07-19 |
Abasic site endonuclease assay App 20070141586 - Kutyavin; Igor V. ;   et al. | 2007-06-21 |
Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis Grant 7,205,105 - Afonina , et al. April 17, 2 | 2007-04-17 |
Process for the synthesis of pyrazolopyrimidines App 20070060744 - Dempcy; Robert O. ;   et al. | 2007-03-15 |
Improved Primer-based Amplification Methods App 20070048758 - Lokhov; Sergey ;   et al. | 2007-03-01 |
Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis App 20070003957 - Afonina; Irina A. ;   et al. | 2007-01-04 |
Fluorescent quenching detection reagents and methods App 20060292589 - Reed; Michael W. ;   et al. | 2006-12-28 |
Compounds and methods for fluorescent labeling Grant 7,112,684 - Lukhtanov , et al. September 26, 2 | 2006-09-26 |
Compounds and methods for fluorescent labeling App 20060204990 - Lukhtanov; Eugeny A. ;   et al. | 2006-09-14 |
Phosphonylated fluorescent dyes and conjugates App 20060199955 - Lukhtanov; Eugeny ;   et al. | 2006-09-07 |
Modified oligonucleotides for mismatch discrimination Grant 7,045,610 - Dempcy , et al. May 16, 2 | 2006-05-16 |
Process for the synthesis of pyrazolopyrimidines App 20060014943 - Dempcy; Robert O. ;   et al. | 2006-01-19 |
Tm leveling compositions App 20060003349 - Dempcy; Robert O. ;   et al. | 2006-01-05 |
Compounds and methods for fluorescent labeling App 20050277144 - Lukhtanov, Eugeny A. ;   et al. | 2005-12-15 |
Non-aggregating non-quenching oligomer comprising nucelotide analogs, method of synthesis and use thereof Grant 6,972,328 - Gall , et al. December 6, 2 | 2005-12-06 |
Compounds and methods for fluorescent labeling Grant 6,972,339 - Lukhtanov , et al. December 6, 2 | 2005-12-06 |
Process for the synthesis of pyrazolopyrimidines Grant 6,962,991 - Dempcy , et al. November 8, 2 | 2005-11-08 |
Non-aggregating non-quenching oligomers comprising nucleotide analogs; methods of synthesis and use thereof App 20050239121 - Gall, Alexander A. ;   et al. | 2005-10-27 |
Hybridization-triggered fluorescent detection of nucleic acids Grant 6,951,930 - Dempcy , et al. October 4, 2 | 2005-10-04 |
Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background App 20050214797 - Lokhov, Sergey ;   et al. | 2005-09-29 |
Compounds and methods for fluorescent labeling App 20050176066 - Lukhtanov, Eugeny A. ;   et al. | 2005-08-11 |
Compounds And Methods For Fluorescent Labeling App 20050171340 - Lukhtanov, Eugeny A. ;   et al. | 2005-08-04 |
Compounds and methods for fluorescent labeling App 20050159606 - Lukhtanov, Eugeny A. | 2005-07-21 |
Single nucleotide polymorphism analysis of highly polymorphic target sequences App 20050118623 - Belousov, Yevgeniy ;   et al. | 2005-06-02 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 6,884,584 - Hedgpeth , et al. April 26, 2 | 2005-04-26 |
TM leveling methods App 20050075491 - Dempcy, Robert O. ;   et al. | 2005-04-07 |
Process for the synthesis of pyrazolopyrimidines App 20040191824 - Dempcy, Robert O. ;   et al. | 2004-09-30 |
Fluorescent quenching detection reagents and methods Grant 6,790,945 - Lukhtanov , et al. September 14, 2 | 2004-09-14 |
Non-aggregating non-quenching oligomer comprising nucelotide analogs, method of synthesis and use thereof App 20040116689 - Gall, Alexander A. ;   et al. | 2004-06-17 |
Abasic site endonuclease assay App 20040101893 - Kutyavin, Igor V. ;   et al. | 2004-05-27 |
Fluorescent quenching detection reagents and methods App 20040081959 - Reed, Michael W. ;   et al. | 2004-04-29 |
Fluorescent quenching detection reagents and methods Grant 6,699,975 - Reed , et al. March 2, 2 | 2004-03-02 |
Cross-linking oligonucleotides Grant RE38,416 - Petrie , et al. February 3, 2 | 2004-02-03 |
Tm leveling methods Grant 6,683,173 - Dempcy , et al. January 27, 2 | 2004-01-27 |
Systems and methods for predicting oligonucleotide melting temperature (TmS) App 20030235822 - Lokhov, Sergey G. ;   et al. | 2003-12-25 |
Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof Grant 6,660,845 - Gall , et al. December 9, 2 | 2003-12-09 |
Tmleveling Methods App 20030224359 - Dempcy, Robert O. ;   et al. | 2003-12-04 |
Fluorescent quenching detection reagents and methods Grant 6,653,473 - Reed , et al. November 25, 2 | 2003-11-25 |
Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis App 20030175728 - Belousov, Yevgeniy S. ;   et al. | 2003-09-18 |
Hybridization-triggered fluorescent detection of nucleic acids App 20030113765 - Dempcy, Robert O. ;   et al. | 2003-06-19 |
Fluorescent quenching detection reagents and methods App 20030096254 - Reed, Michael W. ;   et al. | 2003-05-22 |
Process for the synthesis of pyrazolopyrimidines App 20030078413 - Dempcy, Robert O. ;   et al. | 2003-04-24 |
Fluorescent quenching detection reagents and methods App 20030008304 - Reed, Michael W. ;   et al. | 2003-01-09 |
Covalently linked oligonucleotide minor groove binder conjugates Grant 6,486,308 - Kutyavin , et al. November 26, 2 | 2002-11-26 |
Hybridization-triggered fluorescent detection of nucleic acids Grant 6,472,153 - Dempcy , et al. October 29, 2 | 2002-10-29 |
Covalently linked oligonucleotide minor groove binder conjugates Grant 6,426,408 - Kutyavin , et al. July 30, 2 | 2002-07-30 |
Attachment of oligonucleotides to solid supports through Schiff base type linkages for capture and detection of nucleic acids Grant 6,339,147 - Lukhtanov , et al. January 15, 2 | 2002-01-15 |