loadpatents
name:-0.15516185760498
name:-0.16907095909119
name:-0.0012631416320801
Cook; Phillip Dan Patent Filings

Cook; Phillip Dan

Patent Applications and Registrations

Patent applications and USPTO patent grants for Cook; Phillip Dan.The latest application filed is for "nucleoside derivatives as inhibitors of rna-dependent rna viral polyermase".

Company Profile
0.132.65
  • Cook; Phillip Dan - Fallbrook CA
  • Cook; Phillip Dan - Cardiff CA
  • Cook; Phillip Dan - Lake San Marcos CA US
  • Cook; Phillip Dan - Escondido CA
  • Cook; Phillip Dan - Carlsbad CA
  • Cook; Phillip Dan - San Marcos CA
  • Cook; Phillip Dan - Vista CA
  • Cook; Phillip Dan - Lake San Marcis CA
  • Cook; Phillip Dan - Falbrook CA
*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.
Patent Activity
PatentDate
Nucleoside Derivatives As Inhibitors Of Rna-dependent Rna Viral Polyermase
App 20170183373 - Bhat; Balkrishen ;   et al.
2017-06-29
Nucleoside Derivatives As Inhibitors Of Rna-dependent Rna Viral Polymerase
App 20140309412 - Bhat; Balkrishen ;   et al.
2014-10-16
Compositions and methods for non-parenteral delivery of oligonucleotides
Grant 8,691,785 - Teng , et al. April 8, 2
2014-04-08
Compositions And Methods For Non-parenteral Delivery Of Oligonucleotides
App 20130274309 - Teng; Ching-Leou ;   et al.
2013-10-17
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 8,481,712 - Bhat , et al. July 9, 2
2013-07-09
Compositions and methods for non-parenteral delivery of oligonucleotides
Grant 8,377,897 - Teng , et al. February 19, 2
2013-02-19
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20120165515 - Bhat; Balkrishen ;   et al.
2012-06-28
Composition and methods for the pulmonary delivery of nucleic acids
Grant 8,153,602 - Bennett , et al. April 10, 2
2012-04-10
Compositions And Methods For Topical Delivery Of Oligonucleotides
App 20110213014 - Mehta; Rahul C. ;   et al.
2011-09-01
Compositions and methods for topical delivery of oligonucleotides
Grant 7,964,579 - Mehta , et al. June 21, 2
2011-06-21
Novel Tricyclic Nucleosides Or Nucleotides As Therapeutic Agents
App 20100311684 - Cook; Phillip Dan ;   et al.
2010-12-09
Tricyclic nucleosides or nucleotides as therapeutic agents
Grant 7,713,941 - Cook , et al. May 11, 2
2010-05-11
Compositions And Methods For Topical Delivery Of Oligonucleotides
App 20090326045 - Mehta; Rahul C. ;   et al.
2009-12-31
2'-Modified Oligonucleotides
App 20090198047 - Cook; Phillip Dan ;   et al.
2009-08-06
Novel Tricyclic Nucleosides or Nucleotides as Therapeutic Agents
App 20080200423 - Cook; Phillip Dan ;   et al.
2008-08-21
2'-modified Oligonucleotides
App 20080032945 - Cook; Phillip Dan ;   et al.
2008-02-07
Thionucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 7,323,449 - Olsen , et al. January 29, 2
2008-01-29
Nucleoside derivatives as inhibitors of rna-dependent RNA viral polymerase
App 20070275912 - Bhat; Balkrishen ;   et al.
2007-11-29
Compositions and methods for non-parenteral delivery of oligonucleotides
App 20070249551 - Teng; Ching-Leou ;   et al.
2007-10-25
Process For The Synthesis Of 2'-O-Substituted Pyrimidines And Oligomeric Compounds Therefrom
App 20070232798 - Cook; Phillip Dan ;   et al.
2007-10-04
Tricyclic nucleosides or nucleotides as therapeutic agents
Grant 7,268,119 - Cook , et al. September 11, 2
2007-09-11
Derivatized oligonucleotides having improved uptake and other properties
Grant 7,235,650 - Manoharan , et al. June 26, 2
2007-06-26
Novel Tricyclic Nucleosides Or Nucleotides As Therapeutic Agents
App 20070135363 - Cook; Phillip Dan ;   et al.
2007-06-14
Oligonucleotdies having A-DNA form and B-DNA form conformational geometry
App 20070123702 - Manoharan; Muthiah ;   et al.
2007-05-31
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 7,202,224 - Eldrup , et al. April 10, 2
2007-04-10
Gapped 2' Modified Oligonucleotides
App 20070032446 - Cook; Phillip Dan ;   et al.
2007-02-08
Oligonucleolotides having site specific chiral phosphorothioate internucleoside linkages
Grant RE39,464 - Cook , et al. January 9, 2
2007-01-09
Gapped 2' Modified Oligonucleotides
App 20060270624 - Cook; Phillip Dan ;   et al.
2006-11-30
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20060264390 - Eldrup; Anne B. ;   et al.
2006-11-23
Sugar modified oligonucleotides
Grant 7,138,517 - Cook , et al. November 21, 2
2006-11-21
Derivatized oligonucleotides having improved uptake and other properties
Grant 7,125,975 - Manoharan , et al. October 24, 2
2006-10-24
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 7,125,855 - Bhat , et al. October 24, 2
2006-10-24
Derivatized oligonucleotides having improved uptake and other properties
Grant 7,122,649 - Manoharan , et al. October 17, 2
2006-10-17
Oligonucleotides having A-DNA form and B-DNA form conformational geometry
Grant 7,119,184 - Manoharan , et al. October 10, 2
2006-10-10
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20060205686 - Bhat; Balkrishen ;   et al.
2006-09-14
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
Grant 7,105,499 - Carroll , et al. September 12, 2
2006-09-12
Oligonucleotides containing 2'-O-modified purines
Grant 7,101,993 - Cook , et al. September 5, 2
2006-09-05
Amine-derivatized nucleosides and oligonucleosides
Grant 7,037,646 - Cook , et al. May 2, 2
2006-05-02
Gapped oligonucleotides
Grant 7,015,315 - Cook , et al. March 21, 2
2006-03-21
Nucleobase heterocyclic combinatorialization
Grant 6,991,902 - Cook January 31, 2
2006-01-31
C3' -methylene hydrogen phosphonate oligomers and related compounds
Grant 6,974,865 - Cook , et al. December 13, 2
2005-12-13
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20050272676 - Bhat, Balkrishen ;   et al.
2005-12-08
Methods for processing chemical compounds having reactive functional groups
Grant 6,942,966 - Cook September 13, 2
2005-09-13
Derivatized oligonucleotides having improved uptake and other properties
App 20050158727 - Manoharan, Muthiah ;   et al.
2005-07-21
Derivatized oligonucleotides having improved uptake and other properties
Grant 6,919,439 - Manoharan , et al. July 19, 2
2005-07-19
Methods of using mammalian RNase H and compositions thereof
App 20050153921 - Monia, Brett P. ;   et al.
2005-07-14
Guanidinium functionalized intermediates
Grant 6,914,148 - Manoharan , et al. July 5, 2
2005-07-05
Amine-derivatized nucleosides and oligonucleosides
Grant 6,900,297 - Cook , et al. May 31, 2
2005-05-31
Backbone modified oligonucleotide analogues
Grant 6,900,301 - Cook , et al. May 31, 2
2005-05-31
.alpha.-modified nucleoside triphosphates
Grant 6,900,308 - Wyrzykiewicz , et al. May 31, 2
2005-05-31
Gapped 2' modified oligonucleotides
App 20050112563 - Cook, Phillip Dan ;   et al.
2005-05-26
Nucleobase heterocyclic combinatorialization
Grant 6,893,815 - Cook May 17, 2
2005-05-17
Compositions and methods for topical delivery of oligonucleotides
App 20050096287 - Mehta, Rahul C. ;   et al.
2005-05-05
Carbamate-derivatized nucleosides and oligonucleosides
App 20050074771 - Cook, Phillip Dan ;   et al.
2005-04-07
Processes for the synthesis of 2'-O-substituted pyrimidines and oligomeric compounds therefrom
App 20050059815 - Cook, Phillip Dan ;   et al.
2005-03-17
Nucleosidic and non-nucleosidic folate conjugates
Grant 6,861,514 - Cook , et al. March 1, 2
2005-03-01
Derivatized oligonucleotides having improved uptake and other properties
App 20050043219 - Manoharan, Muthiah ;   et al.
2005-02-24
Oligonucleotide analogs having modified dimers
Grant 6,849,723 - Cook , et al. February 1, 2
2005-02-01
Compositions and methods for topical delivery of oligonucleotides
Grant 6,841,539 - Mehta , et al. January 11, 2
2005-01-11
Derivatized oligonucleotides having improved uptake and other properties
Grant 6,831,166 - Manoharan , et al. December 14, 2
2004-12-14
Compositions and methods for non-parenteral delivery of oligonucleotides
App 20040229831 - Teng, Ching-Leou ;   et al.
2004-11-18
Phosphorothioate oligonucleotides having modified internucleoside linkages
Grant 6,811,975 - Cook , et al. November 2, 2
2004-11-02
Carbamate-derivatized nucleosides and oligonucleosides
Grant 6,803,198 - Cook , et al. October 12, 2
2004-10-12
Complex chemical libraries
Grant 6,800,444 - Cook , et al. October 5, 2
2004-10-05
Amine-derivatized nucleosides and oligonucleosides
Grant 6,783,931 - Cook , et al. August 31, 2
2004-08-31
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase of hepatitis C virus
Grant 6,777,395 - Bhat , et al. August 17, 2
2004-08-17
Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals
App 20040142899 - Cook, Phillip Dan ;   et al.
2004-07-22
Peptide nucleic acid combinatorial libraries and improved methods of synthesis
Grant 6,756,199 - Cook , et al. June 29, 2
2004-06-29
Compositions and methods for enhanced biostability and altered biodistribution of oligonucleotides in mammals
Grant 6,753,423 - Cook , et al. June 22, 2
2004-06-22
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
App 20040110717 - Carroll, Steven S. ;   et al.
2004-06-10
Compositions and methods for non-parenteral delivery of oligonucleotides
Grant 6,747,014 - Teng , et al. June 8, 2
2004-06-08
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20040072788 - Bhat, Balkrishen ;   et al.
2004-04-15
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20040067901 - Bhat, Balkrishen ;   et al.
2004-04-08
Nucleotide mimics and their prodrugs
App 20040059104 - Cook, Phillip Dan ;   et al.
2004-03-25
Oligonucleotides containing 2'-0-modified purines
App 20040048826 - Cook, Phillip Dan ;   et al.
2004-03-11
Oligonucleotides having chiral phosphorus linkages
Grant 6,699,979 - Cook March 2, 2
2004-03-02
Gapped 2' modified oligonucleotides
App 20040038274 - Cook, Phillip Dan ;   et al.
2004-02-26
Oligonucleotides having modified nucleoside units
App 20040014108 - Eldrup, Anne B. ;   et al.
2004-01-22
Oligonucleotides having modified nucleoside units
App 20040014957 - Eldrup, Anne ;   et al.
2004-01-22
Methods of enhancing renal uptake of oligonucleotides
App 20040009938 - Manoharan, Muthiah ;   et al.
2004-01-15
2'-O-aminoethyloxyethyl-modified oligonucleotides
Grant 6,673,912 - Manoharan , et al. January 6, 2
2004-01-06
Di-nitrogen heterocycle compositions
Grant 6,660,466 - Cook , et al. December 9, 2
2003-12-09
Modified oligonucleotides
Grant 6,653,458 - Manoharan , et al. November 25, 2
2003-11-25
Process for the synthesis of 2'-O-substituted pyrimidines and oligomeric compounds therefrom
Grant 6,642,367 - Cook , et al. November 4, 2
2003-11-04
Aminooxy-modified nucleosidic compounds and oligomeric compounds prepared therefrom
Grant 6,639,062 - Manoharan , et al. October 28, 2
2003-10-28
C3'-methylene hydrogen phosphonate oligomers and related compounds
Grant 6,639,061 - Cook , et al. October 28, 2
2003-10-28
Method of using modified oligonucleotides for hepatic delivery
App 20030191075 - Cook, Phillip Dan ;   et al.
2003-10-09
2' -modified oligonucleotides
App 20030187240 - Cook, Phillip Dan ;   et al.
2003-10-02
Oligonucleotide analogs having modified dimers
App 20030181693 - Cook, Phillip Dan ;   et al.
2003-09-25
Derivatized oligonucleotides having improved uptake and other properties
App 20030175751 - Manoharan, Muthiah ;   et al.
2003-09-18
Compositions and methods for modulating RNA
Grant 6,610,663 - Cook , et al. August 26, 2
2003-08-26
2'-O-aminoethyloxyethyl-modified oligonucleotides
Grant 6,600,032 - Manoharan , et al. July 29, 2
2003-07-29
C3' -methylene hydrogen phosphonate oligomers and related compounds
App 20030139586 - Cook, Phillip Dan ;   et al.
2003-07-24
Guanidinium functionalized nucleotides and precursors thereof
Grant 6,593,466 - Manoharan , et al. July 15, 2
2003-07-15
Alpha modified nucleoside triphosphates
App 20030129615 - Wyrzykiewicz, Tadeusz ;   et al.
2003-07-10
Guanidinium functionalized oligomers and methods
App 20030092046 - Manoharan, Muthiah ;   et al.
2003-05-15
Aminooxy-modified Nucleosidic Compounds And Oligomeric Compounds Prepared Therefrom
App 20030088079 - MANOHARAN, MUTHIAH ;   et al.
2003-05-08
Derivatized oligonucleotides having improved uptake and other properties
App 20030064492 - Manoharan, Muthiah ;   et al.
2003-04-03
Guanidinium functionalized oligonucleotides and method/synthesis
Grant 6,534,639 - Manoharan , et al. March 18, 2
2003-03-18
Process for the synthesis of 2' -O-substituted pyrimidines and oligomeric compounds therefrom
App 20030050454 - Cook, Phillip Dan ;   et al.
2003-03-13
2'modified oligonucleotides
Grant 6,531,584 - Cook , et al. March 11, 2
2003-03-11
Backbone modified oligonucleotide analogues
App 20030045705 - Cook, Phillip Dan ;   et al.
2003-03-06
Oligonucleotide-folate conjugates
Grant 6,528,631 - Cook , et al. March 4, 2
2003-03-04
Compositions and methods for non-parenteral delivery of oligonucleotides
App 20030040497 - Teng, Ching-Leou ;   et al.
2003-02-27
Carbamate-derivatized nucleosides and oligonucleosides
App 20030039977 - Cook, Phillip Dan ;   et al.
2003-02-27
Nucleobase heterocyclic combinatorialization
App 20030003505 - Cook, Phillip Dan
2003-01-02
Sugar modified oligonucleotides
App 20030004325 - Cook, Phillip Dan ;   et al.
2003-01-02
Nucleotides having chiral phosphorus linkages
Grant 6,500,945 - Cook December 31, 2
2002-12-31
Backbone-modified oligonucleotide analogs and methods for using same
App 20020183502 - Mesmaeker, Alain De ;   et al.
2002-12-05
Derivatized oligonucleotides having improved uptake and other properties
App 20020177150 - Manoharan, Muthiah ;   et al.
2002-11-28
Compositions and methods for modulating RNA
App 20020160972 - Cook, Phillip Dan ;   et al.
2002-10-31
Gapped 2' modified oligonucleotides
App 20020160379 - Cook, Phillip Dan ;   et al.
2002-10-31
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
App 20020147160 - Bhat, Balkrishen ;   et al.
2002-10-10
Oligonucleotides having chiral phosphorus linkages
App 20020137921 - Cook, Phillip Dan
2002-09-26
Sugar-modified gapped oligonucleotides
Grant 6,451,991 - Martin , et al. September 17, 2
2002-09-17
Oligonucleotides having site specific chiral phosphorothioate internucleoside linkages
Grant 6,440,943 - Cook , et al. August 27, 2
2002-08-27
Oligonucleotide analogs having modified dimers
Grant 6,420,549 - Cook , et al. July 16, 2
2002-07-16
Sugar modified oligonucleotides
Grant 6,399,754 - Cook June 4, 2
2002-06-04
Derivatized oligonucleotides having improved uptake and other properties
Grant 6,395,492 - Manoharan , et al. May 28, 2
2002-05-28
Nucleosidic and non-nucleosidic folate conjugates
App 20020049163 - Cook, Phillip Dan ;   et al.
2002-04-25
Pyrimidine nucleosides
Grant 6,369,040 - Acevedo , et al. April 9, 2
2002-04-09
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
Grant 6,359,124 - Ecker , et al. March 19, 2
2002-03-19
Compositions and methods for modulating RNA
Grant 6,358,931 - Cook , et al. March 19, 2
2002-03-19
Nucleobase Heterocyclic Combinatorialization
App 20020009748 - COOK, PHILLIP DAN
2002-01-24
Antisense oligonucleotides which have phosphorothioate linkages of high chiral purity and which modulate .beta.I, .beta.II, .gamma., .delta., .EPSILON., .zeta. and .eta. isoforms of human protein kinase C
Grant 6,339,066 - Bennett , et al. January 15, 2
2002-01-15
Nucleosidic and non-nucleosidic folate conjugates
Grant 6,335,434 - Guzaev , et al. January 1, 2
2002-01-01
Compounds having a plurality of nitrogenous substitutents
Grant 6,329,523 - Cook , et al. December 11, 2
2001-12-11
Gapped 2' modified oligonucleotides
Grant 6,326,199 - Cook , et al. December 4, 2
2001-12-04
Carbamate-derivatized nucleosides and oligonucleosides
Grant 6,322,987 - Cook , et al. November 27, 2
2001-11-27
Methods of using mammalian RNase H and compositions thereof
App 20010044145 - Monia, Brett P. ;   et al.
2001-11-22
4-desmethyl nucleoside analogs and oligomers thereof
Grant 6,320,040 - Cook , et al. November 20, 2
2001-11-20
Phosphorothioate oligonucleotides having modified internucleoside linkages
App 20010027251 - Cook, Phillip Dan ;   et al.
2001-10-04
Alkylation of alcohols, amines, thiols and their derivatives by cyclic sulfate intermediates
Grant 6,277,982 - Fraser , et al. August 21, 2
2001-08-21
Thiol-derivatized nucleosides and oligonucleosides
Grant 6,265,558 - Cook , et al. July 24, 2
2001-07-24
Oligonucleotides having chiral phosphorus linkages
App 20010008936 - Cook, Phillip Dan
2001-07-19
Compound for detecting and modulating RNA activity and gene expression
Grant 6,262,241 - Cook , et al. July 17, 2
2001-07-17
Phosphorothioate oligonucleotides having modified internucleoside linkages
Grant 6,242,589 - Cook , et al. June 5, 2
2001-06-05
Oligonucleotides having chiral phosphorus linkages
Grant 6,239,265 - Cook May 29, 2
2001-05-29
Substituted purines and oligonucleotide cross-linking
Grant 6,232,463 - Cook , et al. May 15, 2
2001-05-15
Process for the synthesis of 2'-O-substituted pyrimidines and oligomeric compounds therefrom
Grant 6,222,025 - Cook , et al. April 24, 2
2001-04-24
Oligonucleoside linkages containing adjacent nitrogen atoms
Grant 6,214,551 - Sanghvi , et al. April 10, 2
2001-04-10
PNA combinatorial libraries and improved methods of synthesis
Grant 6,204,326 - Cook , et al. March 20, 2
2001-03-20
Aminooxy-modified oligonucleotides and methods for making same
Grant 6,172,209 - Manoharan , et al. January 9, 2
2001-01-09
Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
Grant 6,166,197 - Cook , et al. December 26, 2
2000-12-26
Carbamate-derivatized nucleosides and oligonucleosides
Grant 6,166,188 - Cook , et al. December 26, 2
2000-12-26
N-2 substituted purines
Grant 6,166,199 - Cook , et al. December 26, 2
2000-12-26
Antibacterial quinazoline compounds
Grant 6,156,758 - Kung , et al. December 5, 2
2000-12-05
Derivatized oligonucleotides having improved uptake and other properties
Grant 6,153,737 - Manoharan , et al. November 28, 2
2000-11-28
Antimicrobial determination of N-(aminoalkyl) and/or N-(Amidoalkyl) dinitrogen heterocyclic compositions
Grant 6,150,129 - Cook , et al. November 21, 2
2000-11-21
2'-O-acetamido modified monomers and oligomers
Grant 6,147,200 - Manoharan , et al. November 14, 2
2000-11-14
Gapped 2' modified oligonucleotides
Grant 6,146,829 - Cook , et al. November 14, 2
2000-11-14
Process for the preparation of 2'-O-alkyl purine phosphoramidites
Grant 6,133,438 - Cook , et al. October 17, 2
2000-10-17
2'-O-aminooxy-modified oligonucleotides
Grant 6,127,533 - Cook , et al. October 3, 2
2000-10-03
Oligomeric compounds having nitrogen-containing linkages
Grant 6,121,433 - Cook , et al. September 19, 2
2000-09-19
Thiol-derivatized oligonucleotides
Grant 6,114,513 - Cook , et al. September 5, 2
2000-09-05
Carbamate-derivatized nucleosides and oligonucleosides
Grant 6,111,085 - Cook , et al. August 29, 2
2000-08-29
Nitrogenous macrocyclic compounds
Grant 6,107,482 - Cook , et al. August 22, 2
2000-08-22
Heteroatomic oligonucleoside linkages
Grant 6,087,482 - Teng , et al. July 11, 2
2000-07-11
Pyrimidine nucleoside compounds and oligonucleoside compounds containing same
Grant 6,060,592 - Acevedo , et al. May 9, 2
2000-05-09
2'-O-Dimethylaminoethyloxyethyl-modified oligonucleotides
Grant 6,043,352 - Manoharan , et al. March 28, 2
2000-03-28
Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
Grant 6,025,482 - Cook , et al. February 15, 2
2000-02-15
2'-modified oligonucleotides
Grant 6,005,087 - Cook , et al. December 21, 1
1999-12-21
Cyclobutyl oligonucleotide surrogates
Grant 6,001,841 - Cook , et al. December 14, 1
1999-12-14
4'-desmethyl nucleoside analogs, and oligomers thereof
Grant 5,998,603 - Cook , et al. December 7, 1
1999-12-07
Backbone modified oligonucleotide analogs and preparation thereof through radical coupling
Grant 5,969,118 - Sanghvi , et al. October 19, 1
1999-10-19
Antisense inhibition of ras gene with chimeric and alternating oligonucleotides
Grant 5,965,722 - Ecker , et al. October 12, 1
1999-10-12
Backbone modified oligonucleotide analogues
Grant 5,965,721 - Cook , et al. October 12, 1
1999-10-12
Gapped 2' modified oligonucleotides
Grant 5,955,589 - Cook , et al. September 21, 1
1999-09-21
2'-O-modified nucleosides and phosphoramidites
Grant 5,914,396 - Cook , et al. June 22, 1
1999-06-22
Phosphate linked oligomers
Grant 5,886,177 - Cook , et al. March 23, 1
1999-03-23
2'-O-modified oligonucleotides
Grant 5,872,232 - Cook , et al. February 16, 1
1999-02-16
Peptide nucleic acid combinatorial libraries
Grant 5,864,010 - Cook , et al. January 26, 1
1999-01-26
Process for the synthesis of 2'-O-substituted pyrimidines
Grant 5,861,493 - Cook , et al. January 19, 1
1999-01-19
2'-modified oligonucleotides
Grant 5,859,221 - Cook , et al. January 12, 1
1999-01-12
Gapped 2'-modified oligonucleotides
Grant 5,856,455 - Cook January 5, 1
1999-01-05
Thiol-derivatized oligonucleosides
Grant 5,852,182 - Cook , et al. December 22, 1
1998-12-22
Oligonucleotides having chiral phosphorus linkages
Grant 5,852,188 - Cook December 22, 1
1998-12-22
PNA combinatorial libraries and improved methods of synthesis
Grant 5,831,014 - Cook , et al. November 3, 1
1998-11-03
Substituted purines and oligonucleotide cross-linking
Grant 5,811,534 - Cook , et al. September 22, 1
1998-09-22
Modified oligonucleotides
Grant 5,808,023 - Sanghvi , et al. September 15, 1
1998-09-15
N-2 substituted purines in oligonucleotides
Grant 5,808,027 - Cook , et al. September 15, 1
1998-09-15
Oligonucleoside linkages containing adjacent nitrogen atoms
Grant 5,792,844 - Sanghvi , et al. August 11, 1
1998-08-11
Complex chemical libraries
Grant 5,780,241 - Cook July 14, 1
1998-07-14
Heteroatomic oligonucleoside linkages
Grant 5,777,092 - Cook , et al. July 7, 1
1998-07-07
Process for the synthesis of 2'-O-substituted pyrimidines
Grant 5,760,202 - Cook , et al. June 2, 1
1998-06-02
Covalently cross-linked oligonucleotides
Grant 5,719,271 - Cook , et al. February 17, 1
1998-02-17
Phosphoramidate and phosphorothiomidate oligomeric compounds
Grant 5,717,083 - Cook , et al. February 10, 1
1998-02-10
PNA-DNA-PNA chimeric macromolecules
Grant 5,700,922 - Cook December 23, 1
1997-12-23
Methods of making conjugated 4' desmethyl nucleoside analog compounds
Grant 5,688,941 - Cook , et al. November 18, 1
1997-11-18
Substituted purines and oligonucleotide cross-linking
Grant 5,681,941 - Cook , et al. October 28, 1
1997-10-28
Heteroatomic oligonucleoside linkages
Grant 5,677,437 - Teng , et al. October 14, 1
1997-10-14
Sugar modified oligonucleotides that detect and modulate gene expression
Grant 5,670,633 - Cook , et al. September 23, 1
1997-09-23
Oligonucleotides for modulating Ha-ras or Ki-ras having phosphorothioate linkages of high chiral purity
Grant 5,661,134 - Cook , et al. August 26, 1
1997-08-26
Oligonucleotides for modulating RAF kinase having phosphorothioate linkages of high chiral purity
Grant 5,654,284 - Cook , et al. August 5, 1
1997-08-05

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