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Treatment of Irritable Bowel Syndrome App 20210212967 - SCHIENE; Klaus ;   et al. | 2021-07-15 |
Parenteral Administration Of Tapentadol App 20200215003 - CHRISTOPH; Thomas ;   et al. | 2020-07-09 |
Pharmaceutical Patch Comprising Lidocaine And Diclofenac For Treating Neuropathic Pain App 20190388360 - NARDI; Antonio ;   et al. | 2019-12-26 |
Tapentadol As A Local Anesthetic App 20190388364 - SCHNEIDER; Johannes ;   et al. | 2019-12-26 |
Administration Regimen For A Pharmaceutical Patch Comprising Lidocaine And Diclofenac App 20190374481 - NARDI; Antonio ;   et al. | 2019-12-12 |
Treatment of Pain Associated with Trigeminal Neuralgia App 20190274974 - CHRISTOPH; Thomas ;   et al. | 2019-09-12 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and antidepressants Grant 10,328,055 - Frosch , et al. | 2019-06-25 |
Pharmaceutical Combination App 20190133971 - SCHIENE; Klaus ;   et al. | 2019-05-09 |
Pharmaceutical combination Grant 10,206,890 - Schiene , et al. Feb | 2019-02-19 |
Treatment of Irritable Bowel Syndrome App 20180200205 - SCHIENE; Klaus ;   et al. | 2018-07-19 |
Substituted oxazole- and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands II Grant 9,771,359 - Frank-Foltyn , et al. September 26, 2 | 2017-09-26 |
Substituted Oxazole- and Thiazole-Based Carboxamide and Urea Derivatives as Vanilloid Receptor Ligands II App 20170253586 - FRANK-FOLTYN; Robert ;   et al. | 2017-09-07 |
Treatment of Irritable Bowel Syndrome App 20170216226 - SCHIENE; Klaus ;   et al. | 2017-08-03 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,629,825 - Frosch , et al. April 25, 2 | 2017-04-25 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 9,624,209 - Frank-Foltyn , et al. April 18, 2 | 2017-04-18 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indo]-4-amine and Antidepressants App 20170065560 - Frosch; Stefanie ;   et al. | 2017-03-09 |
Treatment of Irritable Bowel Syndrome App 20170042836 - SCHIENE; Klaus ;   et al. | 2017-02-16 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20160193183 - FROSCH; Stefanie ;   et al. | 2016-07-07 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]- indol]-4-amine and an anticonvulsant Grant 9,345,689 - Frosch , et al. May 24, 2 | 2016-05-24 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid Grant 9,320,725 - Frosch , et al. April 26, 2 | 2016-04-26 |
Parenteral Administration of Tapentadol App 20160106688 - CHRISTOPH; Thomas ;   et al. | 2016-04-21 |
Pharmaceutical Combination App 20160045458 - SCHIENE; Klaus ;   et al. | 2016-02-18 |
Mixed ORL1/mu-agonists for the Treatment of Pain App 20150342929 - LINZ; Klaus ;   et al. | 2015-12-03 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 9,120,756 - Frank , et al. September 1, 2 | 2015-09-01 |
Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands Grant 9,029,378 - Frank , et al. May 12, 2 | 2015-05-12 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20150099728 - FRANK; Robert ;   et al. | 2015-04-09 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 8,946,204 - Frank , et al. February 3, 2 | 2015-02-03 |
Combination of selected opioids with muscarine antagonists for treating urinary incontinence Grant 8,946,290 - Christoph February 3, 2 | 2015-02-03 |
Aryl or N-heteroaryl substituted methanesulfonamide derivatives as vanilloid receptor ligands Grant 8,937,092 - Frank , et al. January 20, 2 | 2015-01-20 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20150011592 - FRANK; Robert ;   et al. | 2015-01-08 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,791,268 - Frank , et al. July 29, 2 | 2014-07-29 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof to treat pain and other conditions Grant 8,785,474 - Frank , et al. July 22, 2 | 2014-07-22 |
Amine substituted methanesulfonamide derivatives as vanilloid receptor ligands Grant 8,765,733 - Frank , et al. July 1, 2 | 2014-07-01 |
Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations App 20140179686 - LEE; Jeewoo ;   et al. | 2014-06-26 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions Grant 8,735,426 - Frank , et al. May 27, 2 | 2014-05-27 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20140142143 - FRANK; Robert ;   et al. | 2014-05-22 |
Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations Grant 8,710,233 - Lee , et al. April 29, 2 | 2014-04-29 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,642,775 - Frank , et al. February 4, 2 | 2014-02-04 |
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions Grant 8,642,623 - Frank , et al. February 4, 2 | 2014-02-04 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N, N-dimethyl-4-phenyl-4,9' -dihydro-3'H-spiro[cyclohexane-1,1' -pyrano[3,4,b]indol]-4-amine and an Anticonvulsant App 20130317009 - FROSCH; Stefanie ;   et al. | 2013-11-28 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands Grant 8,592,471 - Frank , et al. November 26, 2 | 2013-11-26 |
Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexa- ne-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants App 20130310385 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Pharmaceutical composition comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4'9'-dihydro-3'H-spiro[cyclohexan- e-1,1'-pyrano[3,4,b]indol]-4-amine and a gabapentinoid App 20130310434 - FROSCH; Stefanie ;   et al. | 2013-11-21 |
Substituted sulfonamide compounds Grant 8,580,965 - Oberboersch , et al. November 12, 2 | 2013-11-12 |
Use of 1 phenyl-3-dimethylamino-propane compounds for treating neuropathic pain Grant 8,536,130 - Christoph , et al. September 17, 2 | 2013-09-17 |
Treatment of Irritable Bowel Syndrome App 20130116334 - SCHIENE; Klaus ;   et al. | 2013-05-09 |
Substituted sulfonamide compounds Grant 8,435,978 - Oberboersch , et al. May 7, 2 | 2013-05-07 |
Aryl or N-heteroaryl Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079377 - Frank; Robert ;   et al. | 2013-03-28 |
Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079373 - FRANK; Robert ;   et al. | 2013-03-28 |
Amine Substituted Methanesulfonamide Derivatives as Vanilloid Receptor Ligands App 20130079320 - FRANK; Robert ;   et al. | 2013-03-28 |
Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20130029995 - FRANK; Robert ;   et al. | 2013-01-31 |
Substituted Heterocyclic Aza Compounds App 20130029961 - FRANK; Robert ;   et al. | 2013-01-31 |
Substituted Heteroaromatic Pyrazole-Containing Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20130029962 - FRANK; Robert ;   et al. | 2013-01-31 |
Substituted aromatic carboxamide and urea derivatives as vanilloid receptor ligands Grant 8,334,315 - Frank , et al. December 18, 2 | 2012-12-18 |
Treatment of Pain Associated with Trigeminal Neuralgia App 20120309840 - CHRISTOPH; Thomas ;   et al. | 2012-12-06 |
Vanilloid Receptor Ligand Compounds, Pharmaceutical Compositions Containing Them, a Method of Producing Them and the Use Thereof to Treat Pain and Various Other Conditions App 20120302602 - Frank; Robert ;   et al. | 2012-11-29 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20120258946 - FRANK; Robert ;   et al. | 2012-10-11 |
Parenteral Administration of Tapentadol App 20120225951 - CHRISTOPH; Thomas ;   et al. | 2012-09-06 |
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions Grant 8,252,816 - Frank , et al. August 28, 2 | 2012-08-28 |
Substituted Bicyclic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20120115893 - FRANK; Robert ;   et al. | 2012-05-10 |
Substituted Heteroaromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands App 20120115903 - Frank; Robert ;   et al. | 2012-05-10 |
Substituted Cyclic Carboxamide and Urea Derivatives as Ligands of the Vanilloid Receptor App 20120046301 - FRANK; Robert ;   et al. | 2012-02-23 |
Axomadol or a Metabolite Thereof for Use in the Treatment of Irritable Bowel Syndrome App 20120022294 - Schiene; Klaus ;   et al. | 2012-01-26 |
Combination of Selected Opioids with Muscarine Antagonists for Treating Urinary Incontinence App 20120016023 - CHRISTOPH; Thomas | 2012-01-19 |
Tapentadol for use in the treatment of irritable bowel syndrome App 20120004317 - SCHIENE; Klaus ;   et al. | 2012-01-05 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them, and use thereof for treating pain and other conditions Grant 8,084,484 - Frank , et al. December 27, 2 | 2011-12-27 |
Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof to Treat Pain and Other Conditions App 20110301156 - Frank; Robert ;   et al. | 2011-12-08 |
Substituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain Grant 8,017,772 - Merla , et al. September 13, 2 | 2011-09-13 |
Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions App 20110184020 - FRANK; Robert ;   et al. | 2011-07-28 |
Substituted tetrahydropyrrolopyrazine compounds and the use thereof in pharmaceutical compositions Grant 7,879,858 - Merla , et al. February 1, 2 | 2011-02-01 |
Mixed Orl1/mu-agonists For The Treatment Of Pain App 20110015220 - LINZ; KLAUS ;   et al. | 2011-01-20 |
Substituted Aromatic Carboxamide and Urea Derivatives as Vanilloid Receptor Ligands App 20110003795 - FRANK; Robert ;   et al. | 2011-01-06 |
Substituted Phenylureas and Phenylamides as Vanilloid Receptor Ligands App 20100331381 - Frank; Robert ;   et al. | 2010-12-30 |
Substituted Sulfonamide Compounds App 20100324009 - OBERBOERSCH; Stefan ;   et al. | 2010-12-23 |
Substituted Sulfonamide Compounds App 20100317644 - OBERBOERSCH; Stefan ;   et al. | 2010-12-16 |
Use of 1-Phenyl-3-dimethylamino-propane Compounds for Treating Neuropathic Pain App 20100311842 - CHRISTOPH; Thomas ;   et al. | 2010-12-09 |
Pharmaceutical Combination App 20100190752 - Schiene; Klaus ;   et al. | 2010-07-29 |
Pharmaceutical Combination App 20100063148 - Christoph; Thomas ;   et al. | 2010-03-11 |
Substituted Tetrahydropyrrolopyrazine Compounds And The Use Thereof In The Treatment And/or Inhibition Of Pain App 20100004252 - MERLA; Beatrix ;   et al. | 2010-01-07 |
Sutstituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain Grant 7,625,900 - Merla , et al. December 1, 2 | 2009-12-01 |
VR1 Receptor Ligands and u-Opioid Receptor Ligands for the Treatment of Pain App 20090286831 - KOEGEL; Babette-Yvonne ;   et al. | 2009-11-19 |
Substituted Tetrahydropyrrolopyrazine Compounds and the Use Thereof in Pharmaceutical Compositions App 20090258880 - MERLA; Beatrix ;   et al. | 2009-10-15 |
Method of Inhibiting Polyneuropathic Pain with 3-(2-Dimethylaminomethylcyclohexyl) Phenol App 20090197960 - CHRISTOPH; Thomas | 2009-08-06 |
Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions App 20090156590 - FRANK; Robert ;   et al. | 2009-06-18 |
Vanilloid receptor ligands, pharmaceutical compositions containing them, process for making them and use thereof for treating pain and other conditions App 20080275044 - Frank; Robert ;   et al. | 2008-11-06 |
Use of 1-Phenyl-3-Dimethylamino-propane Compounds for Treating Neuropathic Pain App 20080269326 - Christoph; Thomas ;   et al. | 2008-10-30 |
Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions App 20080269289 - Frank; Robert ;   et al. | 2008-10-30 |
Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process For Making Them, and Use Thereof For Treating Pain and Other Conditions App 20080262039 - FRANK; Robert ;   et al. | 2008-10-23 |
Substituted Sulfonamide Compounds App 20080249128 - OBERBOERSCH; Stefan ;   et al. | 2008-10-09 |
Substituted bicyclic imidazo-3-ylamine compounds Grant 7,420,056 - Kuehnert , et al. September 2, 2 | 2008-09-02 |
Substituted Tetrahydropyrrolopyrazine Compounds and the Use Thereof in the Treatment and/or Inhibition of Pain App 20080167315 - Merla; Beatrix ;   et al. | 2008-07-10 |
Substituted Sulfonamide Compounds App 20080153843 - OBERBOERSCH; Stefan ;   et al. | 2008-06-26 |
Mixed ORL1/mu-agonists for the treatment of pain App 20080125475 - LINZ; KLAUS ;   et al. | 2008-05-29 |
Compositions and methods for the treatment of urinary incontinence Grant 7,361,690 - Christoph , et al. April 22, 2 | 2008-04-22 |
Substituted Bicyclic Imidazo-3-ylamine Compounds App 20070155965 - KUHNERT; SVEN ;   et al. | 2007-07-05 |
VGLUT-specific dsRNA compounds App 20070117771 - Gillen; Clemens ;   et al. | 2007-05-24 |
Novel Vanilloid Receptor Ligands And Use Thereof For The Production Of Pharmaceutical Preparations App 20070105861 - Lee; Jeewoo ;   et al. | 2007-05-10 |
Pharmaceutical compositions containing aryl or heteroaryl azolylcarbinol compounds App 20060194860 - Gillen; Clemens ;   et al. | 2006-08-31 |
Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence Grant 7,008,939 - Christoph March 7, 2 | 2006-03-07 |
Metabolites of 1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol and their use in the treatment of urinary incontinence App 20050137145 - Kurth, Burkhard ;   et al. | 2005-06-23 |
Use of 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds for treatment of urinary incontinence Grant 6,908,944 - Christoph , et al. June 21, 2 | 2005-06-21 |
Compositions and methods for the treatment of urinary incontinence App 20050065120 - Christoph, Thomas ;   et al. | 2005-03-24 |
Use of 1-phenyl-3-dimethylaminopropane compounds for treatment of urinary incontinence Grant 6,841,575 - Christoph , et al. January 11, 2 | 2005-01-11 |
Combination of selected opioids with muscarine antagonists for treating urinary incontinence App 20040242617 - Christoph, Thomas | 2004-12-02 |
Use of buprenorphine for the manufacture of a transdermal delivery device for the treatment of urinary incontinence, especially urge incontinence App 20040228906 - Bartholomaeus, Johannes ;   et al. | 2004-11-18 |
Active substance combination containing a compound with an opioid effect and at least one further compound of formula 1 App 20040116352 - Chizh, Boris ;   et al. | 2004-06-17 |
Utilization of buprenorphine in urinary incontinence therapy App 20040102468 - Bartholomaeus, Johannes ;   et al. | 2004-05-27 |
Active substance combination containing an opioid having a fentanyl-type structure and ketamine App 20040092531 - Chizh, Boris ;   et al. | 2004-05-13 |
Use of 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds for treatment of urinary incontinence App 20040043968 - Christoph, Thomas ;   et al. | 2004-03-04 |
Use of 1-phenyl-3-dimethylaminopropane compounds for treatment of urinary incontinence App 20040034105 - Christoph, Thomas ;   et al. | 2004-02-19 |
Use of weak opioids and mixed opioid agonists/antagonists for treatment of urinary incontinence App 20040029905 - Christoph, Thomas | 2004-02-12 |
Compositions and methods for the treatment of urinary incontinence App 20040029878 - Christoph, Thomas ;   et al. | 2004-02-12 |
Use of (+)-tramadol, O-demethyltramadol or (+)-O-demethyl-tramadol, O-desmethyl-N-mono-desmethyl-tramadol or (+)- O-desmethyl-N-mono-desmethyltramadol Grant 6,660,774 - Christoph , et al. December 9, 2 | 2003-12-09 |
Medicament for combating respiratory depression App 20030130203 - Christoph, Thomas ;   et al. | 2003-07-10 |
Use of (+)-tramadol, O-demethyltramadol or (+)-O-demethyl-tramadol, O-desmethyl-N-mono-desmethyl-tramadol or (+)- O-desmethyl-N-mono-desmethy- ltramadol for the treatment of urinary incontinence App 20030069314 - Christoph, Thomas ;   et al. | 2003-04-10 |
Potassium channel activators and their use Grant 6,342,517 - Esch , et al. January 29, 2 | 2002-01-29 |