Patent | Date |
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Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Grant 11,447,777 - Brown September 20, 2 | 2022-09-20 |
Therapeutic inhibition of lactate dehydrogenase and agents therefor Grant 11,359,203 - Brown , et al. June 14, 2 | 2022-06-14 |
Methods and compositions for inhibiting expression of LDHA Grant 11,286,488 - Brown , et al. March 29, 2 | 2022-03-29 |
Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Grant 11,208,658 - Brown , et al. December 28, 2 | 2021-12-28 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20210230604 - BROWN; Bob D. ;   et al. | 2021-07-29 |
Methods and compositions for the specific inhibition of transthyretin (TTR) by double stranded RNA Grant 11,066,672 - Brown , et al. July 20, 2 | 2021-07-20 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 11,060,093 - Brown , et al. July 13, 2 | 2021-07-13 |
Therapeutic inhibition of lactate dehydrogenase and agents therefor Grant 11,053,502 - Brown , et al. July 6, 2 | 2021-07-06 |
Methods And Compositions For The Specific Inhibition Of Alpha-1 Antitrypsin By Double-stranded Rna App 20210180061 - BROWN; Bob D. ;   et al. | 2021-06-17 |
Therapeutic Inhibition Of Lactate Dehydrogenase And Agents Therefor App 20210180068 - BROWN; Bob D. ;   et al. | 2021-06-17 |
Methods And Compositions For The Specific Inhibition Of Complement Component 5(c5) By Double-stranded Rna App 20210139903 - BROWN; Bob D. ;   et al. | 2021-05-13 |
Methods And Compositions For The Specific Inhibition Of Antithrombin 3 (at3) By Double-stranded Rna App 20210095279 - BROWN; Bob D. ;   et al. | 2021-04-01 |
Methods and compositions for the specific inhibition of complement component 5(C5) by double-stranded RNA Grant 10,954,517 - Brown , et al. March 23, 2 | 2021-03-23 |
Compositions And Methods For Inhibiting Gys2 Expression App 20210062197 - BROWN; Bob D. ;   et al. | 2021-03-04 |
Methods And Compositions For Inhibiting Expression Of Ldha App 20210062199 - BROWN; Bob D. ;   et al. | 2021-03-04 |
Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Grant 10,844,381 - Brown , et al. November 24, 2 | 2020-11-24 |
Methods And Compositions For The Specific Inhibition Of Kras By Asymmetric Double-stranded Rna App 20200318118 - Brown; Bob D. | 2020-10-08 |
Methods And Compositions For Inhibiting Expression Of Ldha App 20200283775 - BROWN; Bob D. ;   et al. | 2020-09-10 |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Grant 10,752,899 - Brown A | 2020-08-25 |
Therapeutic inhibition of lactate dehydrogenase and agents therefor Grant 10,738,311 - Brown , et al. A | 2020-08-11 |
Methods and compositions for the specific inhibition of antithrombin 3 (AT3) by double-stranded RNA Grant 10,689,647 - Brown , et al. | 2020-06-23 |
Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA Grant 10,676,742 - Brown , et al. | 2020-06-09 |
Methods and compositions for the specific inhibition of .beta.-catenin by double-stranded RNA Grant 10,612,023 - Brown , et al. | 2020-04-07 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20200002705 - Brown; Bob D. ;   et al. | 2020-01-02 |
Methods And Compositions For The Specific Inhibition Of Aplha-1 Antitrypsin By Double-stranded Rna App 20190390198 - Brown; Bob D. ;   et al. | 2019-12-26 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 10,487,330 - Brown , et al. Nov | 2019-11-26 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 10,465,195 - Brown , et al. No | 2019-11-05 |
Therapeutic Inhibition Of Lactate Dehydrogenase And Agents Therefor App 20190323014 - Brown; Bob D. ;   et al. | 2019-10-24 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 10,435,692 - Brown , et al. O | 2019-10-08 |
Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Grant 10,370,655 - Brown , et al. | 2019-08-06 |
Methods And Compositions For The Specific Inhibition Of Complement Component 5(c5) By Double-stranded Rna App 20190218550 - Brown; Bob D. ;   et al. | 2019-07-18 |
Therapeutic inhibition of lactate dehydrogenase and agents therefor Grant 10,351,854 - Brown , et al. July 16, 2 | 2019-07-16 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20190211340 - Brown; Bob D. ;   et al. | 2019-07-11 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20190194665 - Brown; Bob D. ;   et al. | 2019-06-27 |
Methods And Compositions For The Specific Inhibition Of Transthyretin (ttr) By Double-stranded Rna App 20190144859 - Brown; Bob D. ;   et al. | 2019-05-16 |
Methods And Compositions For The Specific Inhibition Of Beta-catenin By Double-stranded Rna App 20190002879 - Brown; Bob D. ;   et al. | 2019-01-03 |
Methods and compositions for the specific inhibition of transthyretin (TTR) by double-stranded RNA Grant 10,150,965 - Brown , et al. Dec | 2018-12-11 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20180291379 - Brown; Bob D. ;   et al. | 2018-10-11 |
Methods And Compositions For The Specific Inhibition Of Antithrombin 3 (at3) By Double-stranded Rna App 20180282723 - BROWN; Bob D. ;   et al. | 2018-10-04 |
Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA Grant 10,072,263 - Brown , et al. September 11, 2 | 2018-09-11 |
Methods and compositions for the specific inhibition of complement component 5(C5) by double-stranded RNA Grant 10,036,017 - Brown , et al. July 31, 2 | 2018-07-31 |
Methods and compositions for the specific inhibition of HIF-1.alpha. by double-stranded RNA Grant 10,011,834 - Brown , et al. July 3, 2 | 2018-07-03 |
Methods And Compositions For The Specific Inhibition Of Kras By Asymmetric Double-stranded Rna App 20180044680 - Brown; Bob D. | 2018-02-15 |
Methods and compositions for the specific inhibition of CKAP5 by double-stranded RNA Grant 9,850,486 - Brown , et al. December 26, 2 | 2017-12-26 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 9,828,606 - Brown , et al. November 28, 2 | 2017-11-28 |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Grant 9,809,819 - Brown November 7, 2 | 2017-11-07 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20170306333 - Brown; Bob D. ;   et al. | 2017-10-26 |
Therapeutic Inhibition Of Lactate Dehydrogenase And Agents Therefor App 20170306332 - Brown; Bob D. ;   et al. | 2017-10-26 |
Ligand-Modified Double-Stranded Nucleic Acids App 20170305956 - Brown; Bob D. ;   et al. | 2017-10-26 |
Methods And Compositions For The Specific Inhibition Of Myc By Double-stranded Rna App 20170275618 - Brown; Bob D. ;   et al. | 2017-09-28 |
Methods and compositions for the specific inhibition of androgen receptor by double-stranded RNA Grant 9,732,347 - Brown , et al. August 15, 2 | 2017-08-15 |
Methods and compositions for the specific inhibition of MCL1 by double-stranded RNA Grant 9,708,605 - Brown , et al. July 18, 2 | 2017-07-18 |
Methods and compositions for the specific inhibition of glycolate oxidase (HAO1) by double-stranded RNA Grant 9,701,966 - Brown , et al. July 11, 2 | 2017-07-11 |
Methods and compositions for the specific inhibition of met by double stranded RNA Grant 9,670,488 - Brown , et al. June 6, 2 | 2017-06-06 |
Methods And Compositions For The Specific Inhibition Of Alpha-1 Antitrypsin By Double-standed Rna App 20170130221 - Brown; Bob D. ;   et al. | 2017-05-11 |
Methods and compositions for the specific inhibition of MYC by double-stranded RNA Grant 9,562,228 - Brown , et al. February 7, 2 | 2017-02-07 |
Methods And Compositions For The Specific Inhibition Of Transthyretin (ttr) By Double-stranded Rna App 20160304870 - Brown; Bob D. ;   et al. | 2016-10-20 |
Methods and compositions for the specific inhibition of alpha-1 antitrypsin by double-stranded RNA Grant 9,458,457 - Brown , et al. October 4, 2 | 2016-10-04 |
Methods And Compositions For The Specific Inhibition Of Myc By Double-stranded Rna App 20160281091 - Brown; Bob D. ;   et al. | 2016-09-29 |
Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA Grant 9,428,752 - Brown , et al. August 30, 2 | 2016-08-30 |
Methods And Compositions For The Specific Inhibition Of Complement Component 5(c5) By Double-stranded Rna App 20160237438 - Brown; Bob D. ;   et al. | 2016-08-18 |
Methods And Compositions For The Specific Inhibition Of Beta-catenin By Double-stranded Rna App 20160186176 - Brown; Bob D. ;   et al. | 2016-06-30 |
METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF HIF-1a BY DOUBLE-STRANDED RNA App 20160177303 - Brown; Bob D. ;   et al. | 2016-06-23 |
Methods and compositions for the specific inhibition of MYC by double-stranded RNA Grant 9,365,850 - Brown , et al. June 14, 2 | 2016-06-14 |
Lipid delivery formulations Grant 9,320,798 - Brown April 26, 2 | 2016-04-26 |
Methods And Compositions For The Specific Inhibition Of Beta-catenin By Double-stranded Rna App 20160053263 - Brown; Bob D. ;   et al. | 2016-02-25 |
Methods of using oligonucleotides comprising a molecular switch Grant 9,243,286 - Arnold, Jr. , et al. January 26, 2 | 2016-01-26 |
Methods and compositions for the specific inhibition of beta-catenin by double stranded RNA Grant 9,243,244 - Brown , et al. January 26, 2 | 2016-01-26 |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Grant 9,200,284 - Brown December 1, 2 | 2015-12-01 |
Methods And Compositions For The Specific Inhibition Of Ckap5 By Double-stranded Rna App 20150315583 - Brown; Bob D. ;   et al. | 2015-11-05 |
Methods And Compositions For The Specific Inhibition Of Myc By Double-stranded Rna App 20150240234 - Brown; Bob D. ;   et al. | 2015-08-27 |
Methods And Compositions For The Specific Inhibition Of Androgen Receptor By Double-stranded Rna App 20150197756 - Brown; Bob D. ;   et al. | 2015-07-16 |
Methods And Compositions For The Specific Inhibition Of Glycolate Oxidase (hao1) By Double-stranded Rna App 20150184160 - Brown; Bob D. ;   et al. | 2015-07-02 |
Methods And Compositions For The Specific Inhibition Of Mcl1 By Double-stranded Rna App 20150065555 - Brown; Bob D. ;   et al. | 2015-03-05 |
Methods And Compositions For The Specific Inhibition Of Kras By Asymmetric Double-stranded Rna App 20150057337 - Brown; Bob D. | 2015-02-26 |
Methods And Compositions For The Specific Inhibition Of Alpha-1 Antitrypsin By Double-stranded Rna App 20150011607 - Brown; Bob D. ;   et al. | 2015-01-08 |
Single stranded extended dicer substrate agents and methods for the specific inhibition of gene expression Grant 8,927,705 - Brown January 6, 2 | 2015-01-06 |
Methods and compositions for the specific inhibition of androgen receptor by double-stranded RNA Grant 8,927,515 - Brown , et al. January 6, 2 | 2015-01-06 |
Methods And Compositions For The Specific Inhibition Of Met By Double Stranded Rna App 20140315983 - Brown; Bob D. ;   et al. | 2014-10-23 |
Methods And Compositions For The Specific Inhibition Of Beta-catenin By Double-stranded Rna App 20140288292 - Brown; Bob D. ;   et al. | 2014-09-25 |
Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA Grant 8,815,825 - Brown , et al. August 26, 2 | 2014-08-26 |
Methods Of Using Oligonucleotides Comprising A Molecular Switch App 20140193815 - Arnold, JR.; Lyle J. ;   et al. | 2014-07-10 |
Methods And Compositions For The Specific Inhibitions Of Egfr By Double-stranded Rna App 20140155462 - Brown; Bob D. ;   et al. | 2014-06-05 |
Methods And Compositions For The Specific Inhibition Of Myc By Double-stranded Rna App 20140107178 - Brown; Bob D. ;   et al. | 2014-04-17 |
Oligonucleotides comprising a molecular switch Grant 8,679,789 - Arnold, Jr. , et al. March 25, 2 | 2014-03-25 |
Lipid Delivery Formulations App 20130225663 - Brown; Bob D. | 2013-08-29 |
Methods And Compositions For The Specific Inhibition Of Androgen Receptor By Double-stranded Rna App 20130131149 - Brown; Bob D. ;   et al. | 2013-05-23 |
Methods And Compositions For The Specific Inhibition Of Kras By Asymmetric Double-stranded Rna App 20130123342 - Brown; Bob D. | 2013-05-16 |
Methods And Compositions For The Specific Inhibition Of Beta-catenin By Double-stranded Rna App 20130109740 - Brown; Bob D. ;   et al. | 2013-05-02 |
Single Stranded Extended Dicer Substrate Agents And Methods For The Specific Inhibition Of Gene Expression App 20130096290 - Brown; Bob D. | 2013-04-18 |
Methods and compositions for the specific inhibition of KRAS by asymmetric double-stranded RNA Grant 8,372,816 - Brown February 12, 2 | 2013-02-12 |
Oligonucleotide probes and primers comprising universal bases for diagnostic purposes Grant 8,153,772 - Brown , et al. April 10, 2 | 2012-04-10 |
Peptide Dicer Substrate Agents And Methods For Their Specific Inhibition Of Gene Expression App 20110111056 - Basu; Sujit K. ;   et al. | 2011-05-12 |
Peptide Dicer Substrate Agents And Methods For Their Specific Inhibition Of Gene Expression App 20110059187 - Basu; Sujit K. ;   et al. | 2011-03-10 |
Methods And Compositions For The Specific Inhibition Of Kras By Asymmetric Double-stranded Rna App 20110021604 - Brown; Bob D. | 2011-01-27 |
Single Stranded Extended Dicer Substrate Agents And Methods For The Specific Inhibition Of Gene Expression App 20110003881 - BROWN; BOB D. | 2011-01-06 |
Antisense oligonucleotides with increased RNase sensitivity Grant 7,790,877 - Riley , et al. September 7, 2 | 2010-09-07 |
Pharmaceutical Gallium Compositions and Methods App 20090275655 - Warrell, JR.; Raymond P. ;   et al. | 2009-11-05 |
Pharmaceutical Gallium Compositions and Methods App 20090275654 - Brown; Bob D. | 2009-11-05 |
Methods and Compositions for Treating Cancer Using BCL-2 Antisense Oligomers, Tyrosine Kinase Inhibitors, and Chemotherapeutic Agents App 20080171718 - Brown; Bob D. | 2008-07-17 |
Dosing and scheduling of oligomers App 20070270371 - Brown; Bob D. | 2007-11-22 |
Combination of gallium compounds with nonchemotherapeutic anticancer agents in the treatment of neoplasia App 20060275308 - Warrell; Raymond P. JR. ;   et al. | 2006-12-07 |
Oligonucleotides comprising a molecular switch App 20050042638 - Arnold, Lyle J. JR. ;   et al. | 2005-02-24 |
Combination of gallium compounds with nonchemotherapeutic anticancer agents in the treatment of neoplasia App 20040191328 - Warrell, Raymond P. JR. ;   et al. | 2004-09-30 |
Amplification primer pairs and use thereof App 20040014129 - Brown, Bob D. | 2004-01-22 |
Oligonucleotide probes and primers comprising universal bases for diagnostic purposes App 20030170711 - Brown, Bob D. ;   et al. | 2003-09-11 |
Oligonucleotide probes and primers comprising universal bases for therapeutic purposes App 20030171315 - Brown, Bob D. ;   et al. | 2003-09-11 |
Oligonucleotide probes and primers comprising universal bases for diagnostic purposes App 20030165888 - Brown, Bob D. ;   et al. | 2003-09-04 |
Antisense oligonucleotides with increased RNase sensitivity App 20030119016 - Riley, Timothy A. ;   et al. | 2003-06-26 |
Antisense oligonucleotides comprising universal and/or degenerate bases App 20030045488 - Brown, Bob D. ;   et al. | 2003-03-06 |
Amplification primer pairs and use thereof App 20020119533 - Brown, Bob D. | 2002-08-29 |