ASTEX THERAPEUTICS LIMITED

Patent Applications and Registrations

Patent applications and USPTO patent grants for ASTEX THERAPEUTICS LIMITED.The latest application filed is for "bicyclic heterocycle compounds and their uses in therapy".

Company Profile

46.165.200

ASTEX THERAPEUTICS LIMITED - Cambridge GB
ASTEX THERAPEUTICS LTD - Cambridge GB
Astex Therapeutics Ltd. - Cambridge GB
ASTEX THERAPEUTICS LIMITED - Cambridge, Cambridgeshire GB
ASTEX THERAPEUTICS LIMITED - Cambridge, Cambridges GB
Astex Therapeutics, Limited - Cambridgeshire N/A GB
Astex Therapeutics, Ltd - Milton Road, Cambridge N/A GB
Astex Therapeutics, Limited - Milton Road, Cambridge GB
ASTEX THERAPEUTICS LTD - Cambridge, Cambridgeshire GB
Astex Therapeutics, Ltd. - Milton Road, Cambridge GB
Astex Therapeutics Limited - Cambrdige GB
Astex Therapeutics LTD - Cambridgeshire GB
ASTEX THERAPEUTICS LIMITED; - US
ASTEX THERAPEUTICS, LTD. - Cambrige UK
ASTEX THERAPEUTICS LIMITED - 436 Cambridge Science Park Milton Road Cambridge UK

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.
Trademarks

Patent Activity

Patent	Date
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20220204503 - CHESSARI; Gianni ; et al.	2022-06-30
Pyrazolyl Quinoxaline Kinase Inhibitors App 20220135544 - SAXTY; Gordon ; et al.	2022-05-05
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20220106287 - CHESSARI; Gianni ; et al.	2022-04-07
Ether Linked Triazoles As Nrf2 Activators App 20220089590 - Cooper; Anthony William James ; et al.	2022-03-24
Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity Grant 11,261,171 - Chessari , et al. March 1, 2	2022-03-01
Combination of isoindolinone derivatives with SGI-110 Grant 11,236,047 - Chessari , et al. February 1, 2	2022-02-01
Bicyclic heterocycle compounds and their uses in therapy Grant 11,225,476 - Chessari , et al. January 18, 2	2022-01-18
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20210276984 - CHESSARI; Gianni ; et al.	2021-09-09
Pyrrolopyrimidine Compounds And Their Uses App 20210253578 - BESONG; Gilbert ; et al.	2021-08-19
Chemical Compounds App 20210238162 - CADILLA; Rodolfo ; et al.	2021-08-05
Ether linked triazoles as NRF2 activators Grant 11,059,816 - Cooper , et al. July 13, 2	2021-07-13
Pharmaceutical Compositions Comprising N-(3,5-dimethoxyphenyl)-n'-(1-methylethyl)-n-[3-(1-methyl-1h-pyrazol-4-yl- )quinoxalin-6-yl]ethane-1,2-diamine App 20210169877 - BROGGINI; Diego Fernando Domenico	2021-06-10
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20210122749 - WOOLFORD; Alison Jo-Anne ; et al.	2021-04-29
Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity Grant 10,981,898 - Chessari , et al. April 20, 2	2021-04-20
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction And Process For Making Them App 20210101887 - HOWARD; Steven ; et al.	2021-04-08
Combinations App 20210038598 - JOVCHEVA; Eleonora ; et al.	2021-02-11
Pharmaceutical compositions comprising N-(3,5-dimethoxyphenyl)-N'-1 methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-di- amine Grant 10,898,482 - Broggini January 26, 2	2021-01-26
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20200325134 - CHESSARI; Gianni ; et al.	2020-10-15
Combinations of an FGFR inhibitor and an IGF1R inhibitor Grant 10,736,900 - Jovcheva , et al. A	2020-08-11
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20200247789A2 -	2020-08-06
Combinations Grant 10,716,787 - Jovcheva , et al.	2020-07-21
Combination Of Isoindolinone Derivatives With Sgi-110 App 20200207711 - CHESSARI; Gianni ; et al.	2020-07-02
Pyrazolyl Quinoxaline Kinase Inhibitors App 20200131153 - SAXTY; Gordon ; et al.	2020-04-30
Bicyclic heterocycle compounds and their uses in therapy Grant 10,618,895 - Chessari , et al.	2020-04-14
Fgfr/pd-1 Combination Therapy For The Treatment Of Cancer App 20200108141 - KARKERA; Jayaprakash ; et al.	2020-04-09
Nrf2 regulators Grant 10,604,509 - Kerns , et al.	2020-03-31
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20200079761 - CHESSARI; Gianni ; et al.	2020-03-12
Nrf2 REGULATORS App 20200079759 - KERNS; Jeffrey K. ; et al.	2020-03-12
N-aryl Pyrazoles As Nrf2 Regulators App 20200071310 - BUDZIK; Brian W. ; et al.	2020-03-05
Ether Linked Triazoles As Nrf2 Activators App 20200071317 - COOPER; Anthony William James ; et al.	2020-03-05
Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity Grant 10,544,132 - Chessari , et al. Ja	2020-01-28
Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity Grant 10,526,311 - Chessari , et al. J	2020-01-07
Pyrazolyl quinoxaline kinase inhibitors Grant 10,519,137 - Saxty , et al. Dec	2019-12-31
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20190375748 - WOOLFORD; Alison Jo-Anne ; et al.	2019-12-12
Nrf2 regulators Grant 10,485,806 - Kerns , et al. Nov	2019-11-26
FGFR/PD-1 combination therapy for the treatment of cancer Grant 10,478,494 - Karkera , et al. Nov	2019-11-19
Quinoxaline derivatives useful as FGFR kinase modulators Grant 10,421,747 - Vermeulen , et al. Sept	2019-09-24
Biaryl pyrazoles as NRF2 regulators Grant 10,364,256 - Callahan , et al.	2019-07-30
Nrf2 REGULATORS App 20190224212 - Kerns; Jeffrey K. ; et al.	2019-07-25
Arylcyclohexyl pyrazoles as NRF2 regulators Grant 10,351,530 - Callahan , et al. July 16, 2	2019-07-16
Pteridines as FGFR inhibitors Grant 10,272,087 - Saxty , et al.	2019-04-30
NRF2 regulators Grant 10,272,095 - Kerns , et al.	2019-04-30
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20190055215 - CHESSARI; Gianni ; et al.	2019-02-21
Isoindolinone Inhibitors Of The Mdm2-p53 Interaction Having Anticancer Activity App 20190016708 - CHESSARI; Gianni ; et al.	2019-01-17
NRF2 Regulators App 20190002454 - BOEHM; Jeffrey Charles ; et al.	2019-01-03
Nrf2 regulators Grant 10,144,731 - Davies , et al. De	2018-12-04
Combinations App 20180296558 - JOVCHEVA; Eleonora ; et al.	2018-10-18
Arylcyclohexyl Pyrazoles As Nrf2 Regulators App 20180282283 - CALLAHAN; James ; et al.	2018-10-04
Biaryl Pyrazoles As Nrf2 Regulators App 20180282349 - CALLAHAN; James ; et al.	2018-10-04
Combinations Grant 10,085,982 - Jovcheva , et al. October 2, 2	2018-10-02
Substituted quinoxalines as FGFR kinase inhibitors Grant 10,052,320 - Woodhead , et al. August 21, 2	2018-08-21
Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors Grant 10,045,982 - Berdini , et al. August 14, 2	2018-08-14
Quinolines as FGFR kinase modulators Grant 10,039,759 - Berdini , et al. August 7, 2	2018-08-07
Quinoxaline Derivatives Useful As Fgfr Kinase Modulators App 20180186775 - VERMEULEN; Wim ; et al.	2018-07-05
Nrf2 REGULATORS App 20180179167 - KERNS; Jeffrey K. ; et al.	2018-06-28
Nrf2 REGULATORS App 20180179187 - KERNS; Jeffrey K. ; et al.	2018-06-28
Nrf2 REGULATORS App 20180169110 - KERNS; Jeffrey K. ; et al.	2018-06-21
Pyrrolopyrimidine Compounds And Their Uses App 20180155351 - Besong; Gilbert ; et al.	2018-06-07
Bicyclic heterocycle compounds and their uses in therapy Grant 9,980,973 - Chessari , et al. May 29, 2	2018-05-29
Pyrazolyl Quinoxaline Kinase Inhibitors App 20180127397 - SAXTY; Gordon ; et al.	2018-05-10
Hydroxybenzamide derivatives and their use as inhibitors of HSP90 Grant 9,914,719 - Chessari , et al. March 13, 2	2018-03-13
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20180065959 - CHESSARI; Gianni ; et al.	2018-03-08
Quinoxaline derivatives useful as FGFR kinase modulators Grant 9,902,714 - Vermeulen , et al. February 27, 2	2018-02-27
Pharmaceutical Compositions Comprising N-(3,5-dimethoxyphenyl)-n'-(1-methylethyl)-n-[3-(1-methyl-1h-pyrazol-4-yl- )quinoxalin-6-yl]ethane-1,2-diamine App 20180021332 - BROGGINI; Diego Fernando Domenico	2018-01-25
Substituted quinoxalines as FGFR kinase inhibitors Grant 9,856,236 - Saxty , et al. January 2, 2	2018-01-02
Pyrazolyl quinoxaline kinase inhibitors Grant 9,850,228 - Saxty , et al. December 26, 2	2017-12-26
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20170334907 - WOOLFORD; Alison Jo-Anne ; et al.	2017-11-23
Bicyclic heterocycle compounds and their uses in therapy Grant 9,783,538 - Chessari , et al. October 10, 2	2017-10-10
Naphthyridine derivative compounds Grant 9,757,364 - Angibaud , et al. September 12, 2	2017-09-12
Compounds Grant 9,737,544 - Angibaud , et al. August 22, 2	2017-08-22
Pharmaceutical compounds Grant 9,730,912 - Thompson August 15, 2	2017-08-15
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20170224705 - CHESSARI; Gianni ; et al.	2017-08-10
Bicyclic heterocycle compounds and their uses in therapy Grant 9,676,768 - Woolford , et al. June 13, 2	2017-06-13
Bicyclic heterocycle compounds and their uses in therapy Grant 9,663,512 - Chessari , et al. May 30, 2	2017-05-30
Combinations App 20170119763 - JOVCHEVA; Eleonora ; et al.	2017-05-04
New Compounds App 20170105978 - ANGIBAUD; Patrick Rene ; et al.	2017-04-20
Quinoxaline Derivatives Useful As Fgfr Kinase Modulators App 20170101396 - VERMEULEN; Wim ; et al.	2017-04-13
Combinations Of An Fgfr Inhibitor And An Igf1r Inhibitor App 20170100406 - JOVCHEVA; Eleonora ; et al.	2017-04-13
Bicyclic heterocycle compounds and their uses in therapy Grant 9,617,283 - Chessari , et al. April 11, 2	2017-04-11
Bicyclic heterocycle compounds and their uses in therapy Grant 9,617,248 - Chessari , et al. April 11, 2	2017-04-11
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20170029419 - CHESSARI; Gianni ; et al.	2017-02-02
Pteridines As Fgfr Inhibitors App 20170000796 - SAXTY; Gordon ; et al.	2017-01-05
Quinolines As Fgfr Kinase Modulators App 20170000781 - BERDINI; Valerio ; et al.	2017-01-05
Naphthyridine derivative compounds Grant 9,527,844 - Angibaud , et al. December 27, 2	2016-12-27
Quinazolinone derivatives useful as FGFR kinase modulators Grant 9,493,426 - Angibaud , et al. November 15, 2	2016-11-15
Nrf2 Regulators App 20160318917 - Boehm; Jeffrey Charles ; et al.	2016-11-03
Pyrazolyl Quinoxaline Kinase Inhibitors App 20160311800 - SAXTY; Gordon ; et al.	2016-10-27
Pyrazolyl quinoxaline kinase inhibitors Grant 9,464,071 - Saxty , et al. October 11, 2	2016-10-11
Bicyclic heterocycle compounds and their uses in therapy Grant 9,458,158 - Buck , et al. October 4, 2	2016-10-04
Pteridines as FGFR inhibitors Grant 9,447,098 - Saxty , et al. September 20, 2	2016-09-20
Quinolines as FGFR kinase modulators Grant 9,439,896 - Berdini , et al. September 13, 2	2016-09-13
Pyrazole Derivatives As Protein Kinase Modulators App 20160250187 - BERDINI; Valerio ; et al.	2016-09-01
SUBSTITUTED PYRIDO[2,3-b]PYRAZINES AS FGFR KINASE INHIBITORS App 20160235744 - BERDINI; Valerio ; et al.	2016-08-18
Pyrrolopyrimidine compounds and their uses Grant 9,416,136 - Besong , et al. August 16, 2	2016-08-16
Substitutued Quinoxalines As Fgfr Kinase Inhibitors App 20160220564 - WOODHEAD; Steven John ; et al.	2016-08-04
New Compounds App 20160213677 - ANGIBAUD; Patrick Rene ; et al.	2016-07-28
Naphthyridine Derivative Compounds App 20160108034 - ANGIBAUD; Patrick Rene ; et al.	2016-04-21
Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors Grant 9,309,242 - Berdini , et al. April 12, 2	2016-04-12
Naphthyridine derivative compounds Grant 9,309,241 - Angibaud , et al. April 12, 2	2016-04-12
Compounds Grant 9,303,030 - Angibaud , et al. April 5, 2	2016-04-05
Substituted quinoxalines as FGFR kinase inhibitors Grant 9,303,029 - Woodhead , et al. April 5, 2	2016-04-05
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20160083377 - BUCK; Ildiko Maria ; et al.	2016-03-24
Substituted quinoxalines as FGFR kinase inhibitors Grant 9,290,478 - Saxty , et al. March 22, 2	2016-03-22
Quinazolinone Derivatives Useful As Fgfr Kinase Modulators App 20160075666 - ANGIBAUD; Patrick Rene ; et al.	2016-03-17
Pyrazole derivatives as protein kinase modulators Grant 9,283,226 - Berdini , et al. March 15, 2	2016-03-15
Substituted Quinoxalines As Fgfr Kinase Inhibitors App 20160031856 - SAXTY; Gordon ; et al.	2016-02-04
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20150353537 - CHESSARI; Gianni ; et al.	2015-12-10
Salt(s) of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7H-pyrrolo- [2,3-D]pyrimidine-6-carboxylic acid dimethylamide and processes of making thereof Grant 9,193,732 - Calienni , et al. November 24, 2	2015-11-24
Pteridines As Fgfr Inhibitors App 20150291589 - Saxty; Gordon ; et al.	2015-10-15
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20150291586 - WOOLFORD; Alison Jo-Anne ; et al.	2015-10-15
Bicyclic heterocycle compounds and their uses in therapy Grant 9,155,743 - Buck , et al. October 13, 2	2015-10-13
Pharmaceutical compounds Grant 9,145,354 - Woodhead , et al. September 29, 2	2015-09-29
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20150266873 - Chessari; Gianni ; et al.	2015-09-24
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20150259359 - Chessari; Gianni ; et al.	2015-09-17
New Compounds App 20150239883 - Angibaud; Patrick Rene ; et al.	2015-08-27
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 9,051,278 - Berdini , et al. June 9, 2	2015-06-09
Bicyclic heterocycle compounds and their uses in therapy Grant 9,018,214 - Woolford , et al. April 28, 2	2015-04-28
Pyrazolyl Quinoxaline Kinase Inhibitors App 20150105368 - SAXTY; Gordon ; et al.	2015-04-16
Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein Grant 9,006,430 - Berdini , et al. April 14, 2	2015-04-14
New Compounds App 20150057293 - Angibaud; Patrick Rene ; et al.	2015-02-26
Pharmaceutical Compounds App 20150051199 - Woodhead; Andrew James ; et al.	2015-02-19
Hydroxybenzamide Derivatives And Their Use As Inhibitors Of HSP90 App 20150045362 - Chessari; Gianni ; et al.	2015-02-12
Anticancer Benzopyrazines Via The Inhibition Of Fgfr Kinases App 20150031669 - Woodhead; Steven John ; et al.	2015-01-29
Pharmaceutical combinations Grant 8,916,552 - Gallagher , et al. December 23, 2	2014-12-23
3,4-disubstituted 1h-pyrazole Compounds And Their Use As Cyclin Dependent Kinase And Glycogen Synthase Kinase-3 Modulators App 20140371213 - BERDINI; Valerio ; et al.	2014-12-18
Bicyclic heterocyclic compounds as FGFR inhibitors Grant 8,895,745 - Berdini , et al. November 25, 2	2014-11-25
Pyrazolyl quinoxaline kinase inhibitors Grant 8,895,601 - Saxty , et al. November 25, 2	2014-11-25
Pharmaceutical combinations Grant 8,883,790 - Gallagher , et al. November 11, 2	2014-11-11
Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors Grant 8,859,582 - Saxty , et al. October 14, 2	2014-10-14
Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors Grant 8,859,583 - Saxty , et al. October 14, 2	2014-10-14
Ortho-condensed Pyridine And Pyrimidine Derivatives (e.g., Purines) As Protein Kinases Inhibitors App 20140303177 - BERDINI; Valerio ; et al.	2014-10-09
Quinolines As Fgfr Kinase Modulators App 20140296236 - Berdini; Valerio ; et al.	2014-10-02
Anticancer Pyridopyrazines Via The Inhibition Of Fgfr Kinases App 20140288053 - Berdini; Valerio ; et al.	2014-09-25
Substituted Benzylamine Compounds, Their Use In Medicine, And In Particular The Treatment Of Hepatitis C Virus (hcv) Infection App 20140288040 - Woodhead; Andrew James ; et al.	2014-09-25
Pyrazole Derivatives As Protein Kinase Modulators App 20140271662 - BERDINI; Valerio ; et al.	2014-09-18
Hydroxybenzamide derivatives and their use as inhibitors of Hsp90 Grant 8,816,087 - Chessari , et al. August 26, 2	2014-08-26
Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein kinases inhibitors Grant 8,809,336 - Berdini , et al. August 19, 2	2014-08-19
Imidazopyridine derivatives as inhibitors of receptor tyrosine kinases Grant 8,796,244 - Berdini , et al. August 5, 2	2014-08-05
Purine and deazapurine derivatives as pharmaceutical compounds Grant 8,796,293 - Davies , et al. August 5, 2	2014-08-05
Pharmaceutical compounds Grant 8,779,132 - Congreve , et al. July 15, 2	2014-07-15
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 8,779,147 - Berdini , et al. July 15, 2	2014-07-15
Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases Grant 8,778,936 - Berdini , et al. July 15, 2	2014-07-15
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20140179666 - Woolford; Alison Jo-Anne ; et al.	2014-06-26
Pyrrolopyrimidine Compounds And Their Uses App 20140135312 - BESONG; Gilbert ; et al.	2014-05-15
Imidazo [1,2-A]pyridine derivatives as FGFR kinase inhibitors for use in therapy Grant 8,722,687 - Saxty , et al. May 13, 2	2014-05-13
Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors App 20140107137 - BERDINI; Valerio ; et al.	2014-04-17
Pyrazole derivatives as protein kinase modulators Grant 8,691,806 - Berdini , et al. April 8, 2	2014-04-08
Pyrrolopyrimidine compounds and their uses Grant 8,685,980 - Besong , et al. April 1, 2	2014-04-01
Pharmaceutical compounds Grant 8,664,218 - Williams , et al. March 4, 2	2014-03-04
Hydrobenzamide derivatives as inhibitors of Hsp90 Grant 8,653,084 - Frederickson , et al. February 18, 2	2014-02-18
Bicyclic Heterocycle Compounds And Their Uses In Therapy App 20140045831 - Buck; Ildiko Maria ; et al.	2014-02-13
Benzimidazole Derivatives And Their Use As Protein Kinase Inhibitors App 20140010892 - BERDINI; Valerio ; et al.	2014-01-09
Imidazole derivatives and their use as modulators of cyclin dependent kinases Grant 8,598,217 - Howard , et al. December 3, 2	2013-12-03
Substituted Benzopyrazin Derivatives As Fgfr Kinase Inhibitors For The Treatment Of Cancer Diseases App 20130267525 - Saxty; Gordon ; et al.	2013-10-10
Ortho-condensed pyridine and pyrimidine derivatives (e.g., purines) as protein kinases inhibitors Grant 8,546,407 - Berdini , et al. October 1, 2	2013-10-01
Pharmaceutical combinations comprising pyrazole derivatives as protein kinase modulators Grant 8,541,461 - Thompson , et al. September 24, 2	2013-09-24
Therapeutic combinations of hydroxybenzamide derivatives as inhibitors of HSP90 Grant 8,530,469 - Chessari , et al. September 10, 2	2013-09-10
Salt(s) Of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo- [2,3-d]pyrimidine-6-carboxylic Acid Dimethylamide And Processes Of Making Thereof App 20130217698 - Calienni; John Vincent ; et al.	2013-08-22
Imidazo[1,2-a]pyridine compounds for use in treating cancer Grant 8,513,276 - Berdini , et al. August 20, 2	2013-08-20
Pharmaceutical Compounds App 20130210820 - Williams; Brian John ; et al.	2013-08-15
Compositions comprising (S)-2-amino-1-(4-chlorophenyl)-1-[4-(1H-pyrazol-4-yl)-phenyl]-ethanol as modulator of protein kinases Grant 8,497,294 - Woodhead , et al. July 30, 2	2013-07-30
Bicyclic heterocyclyl derivatives as FGFR kinase inhibitors for therapeutic use Grant 8,481,531 - Saxty , et al. July 9, 2	2013-07-09
Pharmaceutical combinations of 1-cyclopropyl-3-[3-(5-morpholin-4-ylmethyl-1H-benzoimidazol-2-yl)-1H-pyra- zol-4-yl]-urea Grant 8,435,970 - Curry , et al. May 7, 2	2013-05-07
Pyrrolopyrimidine compounds and their uses Grant 8,415,355 - Brain , et al. April 9, 2	2013-04-09
Combinations of pyrazole kinase inhibitors Grant 8,404,718 - Curry , et al. March 26, 2	2013-03-26
Pyrazolyl Quinazoline Kinase Inhibitors App 20130072457 - Saxty; Gordon ; et al.	2013-03-21
Pharmaceutical compounds Grant 8,399,442 - Berdini , et al. March 19, 2	2013-03-19
Pharmaceutical compounds Grant 8,383,619 - Williams , et al. February 26, 2	2013-02-26
Pyrazole derivatives Grant 8,367,687 - Brain , et al. February 5, 2	2013-02-05
Pyrazole Derivatives As Protein Kinase Modulators App 20130005702 - BERDINI; Valerio ; et al.	2013-01-03
Pharmaceutical compounds Grant 8,343,953 - Davies , et al. January 1, 2	2013-01-01
Pyrrolopyrimidine compounds and their uses Grant 8,324,225 - Brain , et al. December 4, 2	2012-12-04
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide acid addition salts as kinase inhibitors Grant 8,293,767 - Wyatt , et al. October 23, 2	2012-10-23
Pharmaceutical combinations Grant 8,277,807 - Gallagher , et al. October 2, 2	2012-10-02
3,4-disubstituted 1h-pyrazole Compounds And Their Use As Cyclin Dependent Kinase And Glycogen Synthase Kinase-3 Modulators App 20120213791 - BERDINI; Valerio ; et al.	2012-08-23
Pyrazole derivatives as protein kinase modulators Grant 8,247,576 - Berdini , et al. August 21, 2	2012-08-21
Imidazopyridine Derivatives As Inhibitors Of Receptor Tyrosine Kinases App 20120208791 - Berdini; Valerio ; et al.	2012-08-16
Pyrrolopyrimidine Compounds And Their Uses App 20120207763 - BRAIN; Christopher Thomas ; et al.	2012-08-16
Pyrazole Compounds That Modulate The Activity Of Cdk, Gsk And Aurora Kinases App 20120190673 - BERDINI; Valerio ; et al.	2012-07-26
Imidazole Derivatives And Their Use As Modulators Of Cyclin Dependent Kinases App 20120101064 - Howard; Steven ; et al.	2012-04-26
FGFR pharmacophore compounds Grant 8,131,527 - Saxty , et al. March 6, 2	2012-03-06
Imidazo [1,2-a]pyridine Derivatives As Fgfr Kinase Inhibitors For Use In Therapy App 20120041000 - Saxty; Gordon ; et al.	2012-02-16
Bicyclic Heterocyclic Compounds As Protein Tyrosine Kinase Inhibitors App 20120035153 - SAXTY; Gordon ; et al.	2012-02-09
Bicyclic Heterocyclyl Derivatives As Fgfr Kinase Inhibitors For Therapeutic Use App 20120035171 - Saxty; Gordon ; et al.	2012-02-09
Bicyclic Heterocyclic Compounds As Protein Tyrosine Kinase Inhibitors App 20120035152 - SAXTY; Gordon ; et al.	2012-02-09
Pyrazole compounds that modulate the activity of CDK, GSK and aurora kinases Grant 8,110,573 - Berdini , et al. February 7, 2	2012-02-07
Dihydroxyphenyl isoindolylmethanones Grant 8,106,057 - Chessari , et al. January 31, 2	2012-01-31
Hydroxybenzamide derivatives and their use as inhibitors of HSP90 Grant 8,101,648 - Chessari , et al. January 24, 2	2012-01-24
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 8,080,666 - Berdini , et al. December 20, 2	2011-12-20
Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors Grant 8,076,354 - Saxty , et al. December 13, 2	2011-12-13
Bicyclic heterocyclic compounds as protein tyrosine kinase inhibitors Grant 8,071,614 - Saxty , et al. December 6, 2	2011-12-06
4-(2,6-dichloro-benzoylamino)-1h-pyrazole-3-carboxylic Acid Piperidin-4-ylamide Acid Addition Salts As Kinase Inhibitors App 20110274616 - WYATT; Paul Graham ; et al.	2011-11-10
Compositions Comprising (s)-2-amino-1-(4-chlorophenyl)-1-[4-(1h-pyrazol-4-yl)-phenyl]-ethanol As Modulator Of Protein Kinases App 20110269808 - WOODHEAD; Steven John ; et al.	2011-11-03
Benzimidazole Derivatives And Their Use As Protein Kinase Inhibitors App 20110224203 - BERDINI; Valerio ; et al.	2011-09-15
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide acid addition salts as kinase inhibitors Grant 8,013,163 - Wyatt , et al. September 6, 2	2011-09-06
Benzimidazole derivatives and their use as protein kinase inhibitors Grant 7,977,477 - Berdini , et al. July 12, 2	2011-07-12
Pharmaceutical Combinations App 20110159111 - Curry; Jayne Elizabeth ; et al.	2011-06-30
Pyrazole Derivatives As Protein Kinase Modulators App 20110144080 - Berdini; Valerio ; et al.	2011-06-16
Imidazo[4, 5-B]pyridin-2-one and oxazolo[4, 5-B] pyridin-2-one compounds and analogs thereof as cancer therapeutic compounds Grant 7,951,819 - Niculescu-Duvaz , et al. May 31, 2	2011-05-31
Pharmaceutical Combinations App 20110105501 - Gallagher; Neil James ; et al.	2011-05-05
Combinations of Pyrazole Kinase Inhibitors App 20110002879 - CURRY; Jayne Elizabeth ; et al.	2011-01-06
3,4-disubstituted 1h-pyrazole Compounds And Their Use As Cyclin Dependent Kinase And Glycogen Synthase Kinase-3 Modulators App 20110003799 - BERDINI; Valerio ; et al.	2011-01-06
Bicyclic Heterocyclic Compounds As Protein Tyrosine Kinase Inhibitors App 20100331296 - Saxty; Gordon ; et al.	2010-12-30
Compounds Grant 7,855,213 - Arnold , et al. December 21, 2	2010-12-21
Bicyclic Heterocyclic Compounds As Protein Tyrosine Kinase Inhibitors App 20100286113 - Saxty; Gordon ; et al.	2010-11-11
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 7,825,140 - Berdini , et al. November 2, 2	2010-11-02
Aryl-Alkylamines And Heteroaryl-Alkylamines As Protein Kinase Inhibitors App 20100210617 - Woodhead; Steven John ; et al.	2010-08-19
Dihydroxyphenyl isoindolymethanones Grant 7,754,725 - Chessari , et al. July 13, 2	2010-07-13
Pharmaceutical Combinations Comprising Pyrazole Derivatives As Protein Kinase Modulators App 20100166699 - Thompson; Neil Thomas ; et al.	2010-07-01
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 7,745,638 - Berdini , et al. June 29, 2	2010-06-29
Pyrazole Derivatives As That Modulate The Activity Of Cdk, Gsk And Aurora Kinases App 20100160324 - Berdini; Valerio ; et al.	2010-06-24
Pharmaceutical Compounds App 20100152184 - Congreve; Miles Stuart ; et al.	2010-06-17
Pharmaceutical Compounds App 20100130464 - Davies; Thomas Glanmor ; et al.	2010-05-27
Bicyclic Heterocyclic Compounds as FGFR Inhibitors App 20100120761 - Berdini; Valerio ; et al.	2010-05-13
Substituted Piperidines Containing A Heteroarylamide Or Heteroarylphenyl Moiety App 20100120798 - Woodhead; Steven John ; et al.	2010-05-13
Compositions Comprising (s)-2-amino-1-(4-chlorophenyl)-1-[4-(1h-pyrazol-4-yl)-phenyl]-ethanol As Modulator Of Protein Kinases App 20100113551 - Woodhead; Steven John ; et al.	2010-05-06
Hydroxybenzamide derivatives and their use as inhibitors of Hsp90 Grant 7,700,625 - Chessari , et al. April 20, 2	2010-04-20
Substituted Piperidines Having Protein Kinase Inhibiting Activity App 20100093748 - Woodhead; Steven John ; et al.	2010-04-15
Pharmaceutical Combinations Of 1-cyclopropyl-3- [3-(5-m0rphoolin-4-yl-methyl-1h-benzoimidazol-2-yl)- Lh-1-pyrazol-4-yl]- Urea App 20100055094 - Curry; Jayne Elizabeth ; et al.	2010-03-04
Combinations Of Pyrazole Derivatives For The Inhibition Of Cdks And Gsk's App 20100021420 - Lyons; John Francis ; et al.	2010-01-28
Purine And Deazapurine Derivatives As Pharmaceutical Compounds App 20100022564 - Davies; Thomas Glanmor ; et al.	2010-01-28
Pharmaceutical Compounds App 20100016340 - Woodhead; Steven John ; et al.	2010-01-21
Pharmaceutical Compounds App 20100004232 - Berdini; Valerio ; et al.	2010-01-07
Pharmaceutical Compounds App 20100004243 - Congreve; Miles Stuart ; et al.	2010-01-07
4-(2, 6-Dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide for the Treatment of Cancer App 20090318500 - Trewartha; Gary ; et al.	2009-12-24
Pyrrolopyrimidine Compounds and Their Uses App 20090318441 - Brain; Christopher Thomas ; et al.	2009-12-24
Medical Use Of Cyclin Dependent Kinases Inhibitors App 20090318430 - Pike; Andrew ; et al.	2009-12-24
Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds Grant 7,625,922 - Niculescu-Duvaz , et al. December 1, 2	2009-12-01
Pharmaceutical Combinations App 20090263398 - Lyons; John Francis ; et al.	2009-10-22
Pharmaceutical Compounds App 20090253718 - Davies; Thomas Glanmor ; et al.	2009-10-08
Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors App 20090247538 - Berdini; Valerio ; et al.	2009-10-01
New Compounds 835 App 20090233943 - Burrows; Jeremy Nicholas ; et al.	2009-09-17
Hydroxybenzamide derivatives and their use as inhibitors of HSP90 App 20090215772 - Chessari; Gianni ; et al.	2009-08-27
Pyrimidine Derivatives As HSP90 Inhibitors App 20090215777 - Chessari; Gianni ; et al.	2009-08-27
Pharmaceutical Combinations of Diazole Derivatives for Cancer Treatment App 20090142337 - Squires; Matthew Simon	2009-06-04
2-Aminopyrimidin-4-Ones And Their Use For Treating Or Preventing Alpha Beta-Related Pathologies App 20090099217 - Berg; Stefan ; et al.	2009-04-16
Ortho-Condensed Pyridine and Pyrimidine Derivatives (e.g., Purines) as Protein Kinases Inhibitors App 20090099213 - Berdini; Valerio ; et al.	2009-04-16
Pharmaceutical Compounds App 20090036435 - Curry; Jayne Elizabeth ; et al.	2009-02-05
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide acid addition salts as kinase inhibitors App 20090012124 - Wyatt; Paul Graham ; et al.	2009-01-08
Thiazole And Isothiazole Derivatives That Modulate The Activity Of CDK, GSK And Aurora Kinases App 20080312223 - Berdini; Valerio ; et al.	2008-12-18
Pyrazole Derivatives for the Inhibition of CDK'S and GSK'S App 20080306069 - Wyatt; Paul Graham ; et al.	2008-12-11
Pharmaceutical Compounds App 20080306054 - Chessari; Gianni ; et al.	2008-12-11
New Compounds 835 App 20080287460 - Burrows; Jeremy Nicholas ; et al.	2008-11-20
Compounds for Treating Protein-Kinase Mediated Disorders App 20080275029 - Berdini; Valerio ; et al.	2008-11-06
3,4-disubstituted 1h-pyrazole Compounds And Their Use As Cyclin Dependent Kinase And Glycogen Synthase Kinase-3 Modulators App 20080269207 - Berdini; Valerio ; et al.	2008-10-30
3,4-disubstituted 1h-pyrazole Compounds And Their Use As Cyclin Dependent Kinase And Glycogen Synthase Kinase-3 Modulators App 20080200509 - Berdini; Valerio ; et al.	2008-08-21
Pyrazole Derivatives For The Inhibition Of Cdk's And Gsk's App 20080194562 - Wyatt; Paul Graham ; et al.	2008-08-14
Pharmaceutical Compounds App 20080167309 - Berdini; Valerio ; et al.	2008-07-10
Combinations of Pyrazole Kinase Inhibitors and Further Antitumor Agents App 20080161355 - Curry; Jayne Elizabeth ; et al.	2008-07-03
Pharmaceutical Compounds App 20080161251 - Curry; Jayne Elizabeth ; et al.	2008-07-03
Pyrazole Derivatives For The Inhibition Of Cdk's And Gsk's App 20080139620 - Wyatt; Paul Graham ; et al.	2008-06-12
3,4-disubstituted 1H-pyrazole compounds and their use as cyclin dependent kinase and glycogen synthase kinase-3 modulators Grant 7,385,059 - Berdini , et al. June 10, 2	2008-06-10
Pyrazole Compounds that Modulate the Activity of Cdk, Gsk and Aurora Kinases App 20080132495 - Berdini; Valerio ; et al.	2008-06-05
3,4-Disubstituted Pyrazoles as Cyclin Dependent Kinases (Cdk) or Aurora Kinase or Glycogen Synthase 3 (Gsk-3) Inhibitors App 20080004270 - Gill; Adrian Liam ; et al.	2008-01-03
Hydroxybenzamide Derivatives And Their Use As Inhibitors Of HSP90 App 20070276026 - Chessari; Gianni ; et al.	2007-11-29
Crystal structure of cytochrome P450 Grant 7,148,046 - Williams December 12, 2	2006-12-12
Synthesis and screening of ligands using X-ray crystallography Grant 7,149,280 - Jhoti , et al. December 12, 2	2006-12-12