Yes. If the holder of an international registration is a national of, has a domicile in, or has a real and effective business or commercial establishment in the United States and the international registration is based on a U.S. application or registration, then the subsequent designation may be submitted to the USPTO using the electronic form provided through the Trademark Electronic Application System (TEAS) with a USPTO transmittal fee of $100. The holder also has the option of filing a subsequent designation directly with the International Bureau.