U.S. patent number 6,020,152 [Application Number 08/036,453] was granted by the patent office on 2000-02-01 for lymphocyte-associated cell surface protein. This patent grant is currently assigned to Dana-Farber Cancer Institute, Inc.. Invention is credited to Thomas F. Tedder.
United States Patent | 6,020,152 |
Tedder | February 1, 2000 |
A human cDNA sequence encoding lymphocyte-associated cell surface protein LAM-1, which contains domains homologous with binding domains of animal lectins, growth factors, and C3/C4 binding proteins, and the LAM-1 protein encoded by the cDNA sequence, are described. Antagonists to LAM-1 are used in a method of treating a human patient suffering from a lymphocyte-mobilizing condition which involves administering a therapeutic amount of the antagonist in a non-tox pharmaceutical carrier substance.
Inventors: | Tedder; Thomas F. (Wellesley, MA) |
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Assignee: | Dana-Farber Cancer Institute,
Inc. (Boston, MA) |
Family ID: | 23214421 |
Appl. No.: | 08/036,453 |
Filed: | March 24, 1993 |
Application Number | Filing Date | Patent Number | Issue Date | ||
---|---|---|---|---|---|
983606 | Nov 30, 1992 | ||||
730503 | Jul 8, 1991 | ||||
313109 | Feb 21, 1989 | ||||
Current U.S. Class: | 435/69.1; 435/252.3; 536/23.5; 435/320.1 |
Current CPC Class: | A61P 37/06 (20180101); C07K 16/2854 (20130101); A61P 35/04 (20180101); C07K 14/70564 (20130101); A61P 37/00 (20180101); A61K 38/00 (20130101) |
Current International Class: | C07K 16/28 (20060101); C07K 16/18 (20060101); C07K 14/705 (20060101); C07K 14/435 (20060101); A61K 38/00 (20060101); C12P 021/06 () |
Field of Search: | ;435/69.1,252.3,320.1 ;536/27 |
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4835255 | May 1989 | Weissman et al. |
5026537 | June 1991 | Daddona et al. |
5098833 | March 1992 | Lasky et al. |
5216131 | June 1993 | Lasky et al. |
5227369 | July 1993 | Rosen et al. |
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