U.S. patent number 3,905,521 [Application Number 05/471,958] was granted by the patent office on 1975-09-16 for reagent dispenser.
This patent grant is currently assigned to Thyroid Diagnostics, Inc.. Invention is credited to Marshall E. Deutsch, Louis W. Mead.
United States Patent |
3,905,521 |
Mead , et al. |
September 16, 1975 |
Reagent dispenser
Abstract
A standard syringe is converted into a highly reproducible
reagent dispenser by the addition of a coiled spring and a sleeve.
The coiled spring is a compression spring arranged on the piston
rod of the syringe between the finger actuating flange of the rod
and barrel of the syringe for biasing the piston toward the open
end of the barrel, while the sleeve is arranged in the barrel
between the open end thereof and the piston for limiting movement
of the piston toward the open barrel end.
Inventors: |
Mead; Louis W. (Lexington,
MA), Deutsch; Marshall E. (Sudbury, MA) |
Assignee: |
Thyroid Diagnostics, Inc.
(Bedford, MA)
|
Family
ID: |
23873657 |
Appl.
No.: |
05/471,958 |
Filed: |
May 21, 1974 |
Current U.S.
Class: |
222/309; 222/340;
422/923; 604/208 |
Current CPC
Class: |
B01L
3/0217 (20130101); A61M 5/31591 (20130101); A61M
2005/3115 (20130101) |
Current International
Class: |
A61M
5/315 (20060101); B01L 3/02 (20060101); A61M
5/31 (20060101); G01F 011/06 () |
Field of
Search: |
;222/309,340,386,250,43,49 ;73/425.6
;128/234,218A,218C,218F,218PA,278,215 |
References Cited
[Referenced By]
U.S. Patent Documents
Foreign Patent Documents
|
|
|
|
|
|
|
208,502 |
|
Apr 1960 |
|
OE |
|
1,090,449 |
|
Oct 1960 |
|
DT |
|
Primary Examiner: Reeves; Robert B.
Assistant Examiner: Marmor; Charles A.
Attorney, Agent or Firm: O'Brien; Clarence A. Jacobson;
Harvey B.
Claims
What is claimed as new is as follows:
1. In combination with a standard syringe including a barrel member
provided with finger grips, a constricted open end and a discharge
end, a piston slidably arranged in the barrel, and a piston rod
having a cross-shaped cross section and connected to the piston and
arranged extending through the open end of the barrel, the open end
being substantially larger than the cross section of the piston rod
and a gap formed between the open end and the rod, a flange being
provided on an end of the rod extending out of the barrel, and an
annular recess being provided in the constricted open end adjacent
the finger grips and arranged facing the flange; a coiled
compression spring being arranged with coils of the spring around
the rod and seated between the flange and the recess in the
constricted open end of the barrel for biasing the rod and piston
toward the open end; and a sleeve arranged in the barrel between
the open end of the barrel and the piston for limiting movement of
the piston toward the open end of the barrel, the sleeve being a
split sleeve formed by a sheet having a thickness less than the gap
between the piston rod and open end, and bent to close on itself
and of a size which is less than the size of the constricted open
end for permitting passage of the sleeve through the constricted
open end and into the barrel, the constricted open end and the bias
of the sleeve against the barrel causing the sleeve to be retained
inside the barrel abutting the constricted end.
Description
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates generally to a reagent dispenser, and
particularly to the conversion of a standard syringe to a highly
reproducible reagent dispenser.
2. Description of the Prior Art
Devices for dispensing predetermined amounts of a liquid are
generally known to those skilled in the pertinent art. See, for
example, U.S. Pat. No. 2,530,909, issued Nov. 21, 1950 to G. S.
Riggs, U.S. Pat. No. 3,343,539, issued Sept. 26, 1967 to J. H.
Moorhouse, U.S. Pat. No. 3,327,904, issued June 27, 1967 to G. G.
Goda et al., and U.S. Pat. No. 3,430,813, issued Mar. 4, 1969 to R.
Gilmont. These known devices, however, are generally of special
construction, and the cost for obtaining a desired level of
reproducibility of dosage with these known devices is relatively
high.
SUMMARY OF THE INVENTION
It is an object of the present invention to provide a reagent
dispenser having simple yet economical construction of the
dispenser and its constituent parts.
It is another object of the present invention to provide an
inexpensive reagent dispenser having reproducibility that far
exceeds that of much more elaborate commercially available
devices.
It is yet another object of the present invention to provide a
reagent dispenser constructed by converting a standard syringe.
These and other objects are achieved according to the present
invention by providing a reagent dispenser having: a barrel member
provided with an open end and a discharge end; a piston slidably
arranged in the barrel for movement between the open end and the
discharge end; a piston rod connected to the piston and arranged
extending through the open end of the barrel; a spring for biasing
the rod toward the open end of the barrel; and a sleeve arranged in
the barrel for limiting movement of the piston toward the open end
of the barrel. As will be appreciated from the following
description, a reagent dispenser according to the present invention
may be formed by adding a suitable spring and sleeve to a
conventional syringe.
The open end of the barrel is advantageously constricted, with the
sleeve being arranged in the barrel between the constricted open
end and the piston. By forming the sleeve as a split sleeve from a
bent sheet of suitable material, the sleeve may be slipped into the
barrel of a syringe by reducing the size of the sleeve so as to fit
between the constricted opening and the associated piston rod.
The piston rod is preferably provided with a finger actuating
flange on an end of the rod extending out of the barrel, so that a
coiled compression spring may be arranged on the piston rod between
this flange and the open end of the barrel.
These together with other objects and advantages which will become
subsequently apparent reside in the details of construction and
operation as more fully hereinafter described and claimed,
reference being had to the accompanying drawings forming a part
hereof, wherein like numerals refer to like parts throughout.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a perspective view showing a reagent dispenser according
to the present invention.
FIG. 2 is a fragmentary, sectional view taken generally along the
line 2--2 of FIG. 1.
FIG. 3 is a sectional view taken generally along the line 3--3 of
FIG. 2.
FIG. 4 is a perspective view of a sleeve used in forming a reagent
dispenser according to the present invention.
DESCRIPTION OF THE PREFERRED EMBODIMENT
Referring now more particularly to FIGS. 1 and 2 of the drawings, a
reagent dispenser 10 according to the present invention has a
barrel 12 provided with finger grips 38, an open end 14 and a
discharge end 16. Barrel 12, together with the ends thereof, may be
a, for example, standard disposable plastic syringe, and the like,
having a conventional cannula 18 attached thereto as by the
standard luer fitting 20.
A piston 22 is slidably arranged in barrel 12 for movement between
the ends 14 and 16 thereof. This piston may be of conventional
construction, such as well known in the manufacture of the
aforementioned disposable syringe. A piston rod 24 is connected to
piston 22 in the conventional manner for moving the piston toward
the discharge end 16. This piston rod 24, which is arranged
extending through open end 14 of barrel 12, has provided on the end
thereof extending out of barrel 12 a finger actuating flame 26.
This flange 26 is conventionally provided on standard syringes for
selectively depressing rod 24, and thereby piston 22, toward the
discharge end 16 of the syringe barrel 12.
A coiled compression spring 28 is arranged with coils 30 of same
around rod 24 and between flange 26 and open end 14 for resiliently
biasing rod 24 and piston 22 toward the open end of the barrel. A
recess 32 is desirably provided in open end 14 of barrel 12
adjacent finger grips 38 to assist in retaining spring 28 in
position.
Open end 14 of barrel 12 is advantageously constricted, as is
conventional with syringes, and a sleeve 34 arranged in barrel 12
between the constricted open end 14 and the piston 22 for limiting
movement of piston 22 toward open end 14. Sleeve 34 is preferably a
split sleeve formed by a sheet of suitable material, such as steel,
bent to close on itself and form a split 36. In this manner, sleeve
34 may be reduced to a size which is less than the size of the
constricted open end 14 for permitting passage of sleeve 34 through
end 14 and into barrel 12. Thus, the constriction of open end 14
will retain sleeve 34 in place, while the construction of sleeve 34
will permit same to be inserted into a standard syringe.
A reagent dispenser according to the present invention can be made
to dispense any desired volume up to the capacity of the syringe,
which conventionally comes in different capacities. Such dispensing
is repetitive because of the use of the split sleeve 34. By
selecting a sleeve of appropriate size for a volume to be
repetitively dispensed, a reagent dispenser according to the
present invention can achieve reproductibility that far exceeds
that of much more elaborate commercially available devices. Models
have been constructed that dispense with a reproductibility better
than plus or minus 1%.
As can be appreciated from the above description and from the
drawings, when the insert or sleeve 34 is slipped into the barrel
12 of the syringe, the limited space available in constricted open
end 14 forces the sleeve toward its closed, or even into an
overlapping, position. Its tendency to open, however, causes the
sleeve to be retained in position once inside of barrel 12.
Alternatively to the illustrated embodiment, it is also possible to
construct an arrangement according to the present invention wherein
the dispenser is sealed into the cap of a reagent bottle (not
shown). When such an arrangement is employed, it has the further
advantage of permitting inversion of the entire assembly during
filling of the dispenser. Thus, it is possible in this manner to
eliminate all air bubbles from the device in the process of filling
it.
The foregoing is considered as illustrative only of the principles
of the invention. Further, since numerous modifications and changes
will readily occur to those skilled in the art, it is not desired
to limit the invention to the exact construction and operation
shown and described, and accordingly all suitable modifications and
equivalents may be resorted to, falling within the scope of the
invention.
* * * * *