U.S. patent number 3,868,965 [Application Number 05/376,227] was granted by the patent office on 1975-03-04 for drop former for intravenous set.
This patent grant is currently assigned to United States Surgical Corporation. Invention is credited to Douglas G. Noiles, Anthony D. Spasiano.
United States Patent |
3,868,965 |
Noiles , et al. |
March 4, 1975 |
DROP FORMER FOR INTRAVENOUS SET
Abstract
A drop former for use with the drip chamber for an intravenous
set for determining the flow rate of a parenteral fluid. The drop
former has a parenteral fluid passage formed therethrough having an
inlet opening for communicating with a source of parenteral fluid
and an outlet opening for communicating with the drip chamber. The
parenteral fluid passage defines a drop forming orifice for forming
drops of parenteral fluid of predetermined size having an outlet
opening at least as large as its inlet opening. The drop former is
formed form a plastic which absorbs less than about 0.03 percent by
weight water.
Inventors: |
Noiles; Douglas G. (New Canaan,
CT), Spasiano; Anthony D. (Greenwich, CT) |
Assignee: |
United States Surgical
Corporation (Baltimore, MD)
|
Family
ID: |
23484172 |
Appl.
No.: |
05/376,227 |
Filed: |
July 3, 1973 |
Current U.S.
Class: |
137/559;
604/411 |
Current CPC
Class: |
A61M
5/1411 (20130101); A61M 5/162 (20130101); Y10T
137/8359 (20150401); A61M 2005/1623 (20130101) |
Current International
Class: |
A61M
5/162 (20060101); A61M 5/14 (20060101); A61m
005/16 () |
Field of
Search: |
;137/559 ;128/214C,214.2
;222/421 ;141/114,330,331,332,337,329,392 ;251/125 |
References Cited
[Referenced By]
U.S. Patent Documents
Primary Examiner: Klinksiek; Henry T.
Attorney, Agent or Firm: Fleit & Jacobson
Claims
We claim:
1. A drop former for use with a drip chamber for determining the
flow rate of a parenteral fluid, comprising:, body means defining a
parenteral fluid passage therethrough, said parenteral fluid
passage having an inlet opening for communicating with a source of
parenteral fluid and an outlet opening for communicating with a
drip chamber, said parenteral fluid passage defining a drop forming
orifice for forming about 12 to 20 drops of parenteral fluid for
each millimeter of fluid flowing therethrough at the pressures
encountered in intravenous feeding, said outlet opening being at
least as large as said inlet opening, and said body means being
formed from a plastic which absorbs less than about 0.03 percent by
weight water measured over about a twenty-four hour period so that
the size of said drops will not materially change with time or flow
rate.
2. The drop former of claim 1 in which said plastic is
polyethylene, polypropylene, polytetrafluoroethylene, or
fluorinated ethylene propylene.
3. The drop former of claim 1 in which said plastic is
polypropylene.
4. The drop former of claim 1 in which said inlet opening is formed
in a portion of said body means which is of suitable size and shape
for insertion into the discharge opening of a parenteral fluid
passage in a piercer.
5. The drop former of claim 1 in which said outlet opening is
larger than said inlet opening.
6. The drop former of claim 1, in which said parenteral fluid
passage includes a portion upstream of said drop forming orifice of
suitable size for receiving a cannula for forming drops of
parenteral fluid which are smaller than said predetermined
size.
7. The drop former of claim 1 in which said parenteral fluid
passage includes a frusto-conical section adjacent said inlet
opening, a cylindrical section adjacent said outlet opening, and a
tapered intermediate section merging into said frusto-conical and
cylindrical sections.
8. The drop former of claim 1 in which said body means comprises a
cylindrical base portion forming said outlet opening and a tapered
portion attached to said base portion and forming an annular
shoulder therewith for facilitating attachment of said drop former
to a piercer.
9. The drop former of claim 8 in which said tapered portion has a
ring collar on the external surface thereof for the adhesive
attachment of said drop former to said piercer.
10. The drop former of claim 8 in which said base portion includes
an inwardly tapered bottom portion which merges into said outlet
opening forming a sharp cylindrical edge therewith.
11. The drop former of claim 1 in which the ratio of the length of
said drop forming orifice to the diameter of said outlet opening is
at least 2:1.
12. A piercer and flow meter for an intravenous set, comprising: a
piercer having a base and a piercing member with a sharp end for
piercing the closure of a parenteral fluid container, said piercer
defining a parenteral fluid passage for transferring parenteral
fluid from said container, said parenteral fluid passage having an
opening in said piercing member for communicating with said
container and a discharge opening in said base; a drip chamber
attached to said piercer and communicating with said discharge
opening; and a drop former attached to said piercer and comprising
body means defining a parenteral fluid passage therethrough, said
parenteral fluid passage having an inlet opening communicating with
said discharge opening in said piercer and an outlet opening
communicating with said drip chamber, said parenteral fluid passage
defining a drop forming orifice for forming drops of parenteral
fluid of predetermined size which can be visually observed while
falling through said drip chamber for determining the flow rate of
said parenteral fluid, said outlet opening being at least as large
as said inlet opening, and said body means being formed from a
plastic which absorbs less than about 0.03 percent by weight water
measured over about a 24 hour period so that the size of said drops
will not materially change with time of flow rate.
13. The piercer and flow meter of claim 12 in which said plastic is
polyethylene, polypropylene, polytetrafluoroethylene, or
fluorinated ethylene propylene.
14. The piercer and flow meter of claim 12 in which said plastic is
polypropylene.
15. The piercer and flow meter of claim 12 in which the outlet
opening in said drop former is larger than said inlet opening.
16. The piercer and flow meter of claim 12 in which the parenteral
fluid passage in said drop former includes a portion upstream of
said drop forming orifice of suitable size for receiving a cannula
for forming drops of parenteral fluid which are smaller than said
predetermined size.
17. The piercer and flow meter of claim 12 in which the parenteral
fluid passage of said drop former includes a frusto-conical section
adjacent said inlet opening, a cylindrical section adjacent said
outlet opening, and a tapered intermediate section merging into
said frusto-conical and cylindrical sections.
18. the piercer and flow meter of claim 12 in which the body means
of said drop former comprises a cylindrical base portion forming
said outlet opening and a tapered portion attached to said base
portion and forming an annular shoulder therewith for facilitating
attachment of said drop former to said piercer.
19. The piercer and flow meter of claim 18 in which the tapered
portion of said drop former has a ring collar on the external
surface thereof for enabling the adhesive attachment of said drop
former to said piercer.
20. The piercer and flow meter of claim 18 in which the base
portion of said drop former includes an inwardly tapered bottom
portion which merges into said outlet opening forming a sharp
cylindrical edge therewith.
21. The piercer and flow meter of claim 12 in which the outlet
opening of said drop former defines a drop forming orifice for
forming drops of parenteral fluid of such predetermined size that
from 12 to 20 drops are formed for each milliliter of fluid flowing
therethrough.
22. The piercer and flow meter of claim 12 in which the ratio of
the length of said drop forming orifice to the diameter of said
outlet opening is at least 2:1.
Description
BACKGROUND OF THE INVENTION
The present invention relates to an improved drop former for use
with a drip chamber of an intravenous set.
Intravenous sets for the introduction of parenteral fluid through
venipuncture typically include a piercer for insertion into a
parenteral fluid container, a flexible plastic tube for
transporting the parenteral fluid from the container to the
patient, and a needle adapter to which an intravenous needle is
attached. The typical intravenous set also includes a clamp which
closes the internal bore of the flexible tubing to control the flow
rate of the parenteral fluid. The flow rate is determined by a flow
meter, such as a drip chamber, positioned intermediate the piercer
and the needle adapter and upstream of the clamp.
The piercer is conventionally formed from a relatively rigid
plastic such as styrene-acrylonitrile, nylon or rigid polyvinyl
chloride, and includes a piercing member having a sharp end for
piercing the closure of a parenteral fluid container. A parenteral
fluid passage is provided in the piercer for transferring
parenteral fluid from the container to the intravenous set,
typically directly into a drip chamber. The piercer may also be
provided with a vent passage for venting the container when the
parenteral fluid container does not have a separate vent tube. When
a drip chamber is used as the flow meter, the discharge opening of
the parenteral fluid passage in the piercer comprises a drop
forming orifice for forming drops of predetermined size. The drops
emerge from the drop forming orifice and fall through the drip
chamber, where they are counted and the flow rate of the parenteral
fluid determined.
Smaller size drops are preferred in certain applications,
particularly for intravenous sets used in pediatric applications,
and so the drop forming orifice of the piercer is frequently
adapted to accept a plastic plug containing a very small diameter
metal tube or cannula which will form a smaller size drop. This
cannula typically forms 60 drops per milliliter whereas the drop
forming orifice of the piercer will normally form 12, 15 or 20
drops per milliliter. Accordingly, the use of the cannula enables a
much more accurate measurement of small flow rates. In other cases
a plastic insert having a tapered parenteral fluid passage has been
used in place of the plug and cannula. The plastic insert has an
inlet opening of somewhat similar size to the discharge opening of
the piercer and a smaller outlet opening of similar size to the
bore of the cannula. In these cases, the insert has been formed
from a plastic such as polyethylene.
It has been found that the size of the drops formed at the
parenteral fluid discharge opening of a conventional piercer varies
significantly with time. More specifically, variations of 5 to 15
percent have been observed over a twenty-four-hour period, In
general, it has been found that the drop size becomes larger with
time. Further, it has been observed that the size of the drops
formed with the plastic insert for pediatric use not only varies
with time, but with flow rate and that as the flow rate becomes
higher, the drop size becomes smaller. No significant change in
drop size has been observed with respect to the metal cannula;
however, it is not feasible to use a metal piercer because of cost
considerations and because the intravenous set is discarded after
one use. Also, it is not feasible to form a drop former for
insertion into the parenteral fluid discharge opening of a piercer
from metal because of the difficulty in properly shaping a small
metal insert and the difficulty in attaching the metal insert to
the plastic piercer.
In view of the foregoing, an object of the present invention is to
provide an improved drop former for use with the drip chamber of an
intravenous set.
A further object of the present invention is to provide a drop
former for an intravenous set which forms drops of predetermined
size, which size does not vary significantly with time or flow
rate.
Still another object of the present invention is to provide a drop
former for an intravenous set which can be inserted into the
parenteral fluid discharge opening of a conventional piercer.
Yet another object of the present invention is to provide a drop
former which is adapted to receive a conventional metal cannula for
forming drops of suitable size for pediatric use.
Still another object of the present invention is to provide an
economical drop former which can be easily fabricated and will
carry out the other objects of the present invention.
SUMMARY OF THE INVENTION
The present invention relates to an improved drop former having a
parenteral fluid passage with an inlet opening for communicating
with a source of parenteral fluid and an outlet opening for
communicating with a drip chamber. The parenteral fluid passage
defines a drop forming orifice for forming drops of parenteral
fluid of predetermined size and has an outlet opening which is at
least as large as its inlet opening. The drop former is formed from
a plastic which absorbs less than about 0.03 percent by weight
water. It has been found that the volume of the drops formed at the
outlet opening of the drop former will not vary significantly with
time or parenteral fluid flow rate. Examples of plastics which
absorb less than about 0.03 percent by weight water are
polyethylene, polypropylene, polytetrafluoroethylene and
fluorinated ethylene propylene. Of these materials, polypropylene
is most preferred.
The plastics such as polypropylene from which the drop former of
the present invention is formed are not well suited for forming
piercers because of their lack of sufficient rigidity and because
of their inability to be adhesively attached to the materials such
as polyvinyl chloride from which drip chambers are conventionally
formed. Accordingly, the drop former is typically formed of
suitable size and shape so that it can be inserted into the
parenteral fluid discharge opening of a conventional piercer. The
drop former of the present invention is preferably formed to accept
a conventional metal cannula so that it can be adapted for use
where the measurement of very small flow rates is required, such as
in pediatric applications.
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is a view of a conventional intravenous set incorporating
the drop former of the present invention.
FIG. 2 is an enlarged, exploded view of the piercer and drop former
of FIG. 1. FIG. 3 is an enlarged, vertical cross-sectional view of
the piercer and drop former of FIG. 1.
FIG. 4 is an enlarged, vertical cross-sectional view of the drop
former of the present invention.
FIG. 5 is an enlarged, exploded view of the drop former of the
present invention shown in use with a cannula for pediatric
use.
FIG. 6 is an enlarged, vertical cross-sectional view of the drop
former of the present invention with a cannula inserted
therein.
FIG. 7 is an enlarged, vertical cross-sectional view of a modified
form of the drop former of the present invention shown inserted
into the parenteral fluid discharge opening of a piercer.
DESCRIPTION OF THE PREFERRED EMBODIMENTS
Referring to FIG. 1, intravenous set 10 includes piercer 12 for
insertion into a parenteral fluid container, flexible plastic tube
14, typically polyvinyl chloride tubing, for transporting the
parenteral fluid from the container to the patient, and needle
adapter 16 to which an intravenous needle can be attached.
Intravenous set 10 also includes clamp 18 for closing the internal
bore of flexible tubing 14 to control the flow rate of the
parenteral fluid. the flow rate is determined by use of drip
chamber 20, attached to the base of piercer 12. Drip chamber 20 is
formed from a transparent material, typically flexible polyvinyl
chloride. Drop former 22 of the present invention is shown attached
to piercer 12 and in communication with drip chamber 20.
In using intravenous set 10, clamp 18 is closed and piercer 12
inserted into a parenteral fluid container (not shown). The
container is then appropriately suspended and the flow of
parenteral fluid is started, such as by squeezing drip chamber 20
until it is partially full. An intravenous needle (not shown) is
attached to needle adapter 16, and clamp 18 opened to allow the
parenteral fluid to displace air in tubing 14, needle adapter 16,
and the intravenous needle. Subsequently, clamp 18 is closed and
venipuncture performed. The flow rate of parenteral fluid is then
adjusted by using clamp 18. Parenteral fluid flows out of the
parenteral fluid container through piercer 12, is formed into drops
of known size in drop former 22, and falls through drip chamber 20,
wherein the drip count can be visually observed to determine the
flow rate.
Referring now to FIG. 2, piercer 12 comprises base 24 and piercing
member 26. Piercing member 26 has sharp end 28 for piercing the
closure of parenteral fluid container. Base 24 of piercer 12
includes laterally extending projection 30 which is closed by air
filter cap 32. Filter cap 32 contains semipermeable air filter
material which is permeable to air but impermeable to liquid at the
pressure differentials encountered, and serves to filter incoming
air for venting the parenteral fluid container. A typical air
filter material comprises a thin mat of felted microscopic fibers
of Teflon on a woven fiberglass substrate. Drip chamber 20 is
adhesively attached to annular flange 34 which projects from the
base 24 of piercer 12. Base 24 of piercer 12 also includes
cylindrical projection 36 to which drop former 22 is attached.
Piercer 12 is typically formed from a moldable plastic such as
styrene-acrylonitrile, nylon, or rigid polyvinyl chloride.
Drop former 22 includes a cylindrical base portion 38, tapered
intermediate portion 40, and cylindrical top portion 42. Tapered
intermediate portion 40 is of smaller diameter than cylindrical
base portion 38 forming annular shoulder 44 therebetween. The
bottom of base portion 38 is tapered inwardly at 46. Drop former 22
is formed from a plastic which absorbs less than about 0.03 percent
by weight water when measured over a twenty-four hour period.
Examples of suitable plastics are polyethylene having a moisture
absorption of less than 0.01 percent, polypropylene having a
moisture absorption of less than 0.01 to 0.03 percent, and
polytetrafluoroethylene and fluorinated ethylene propylene, each
having a moisture absorption of about 0.01 percent. Polyethylene
and polypropylene are the generally preferred plastics, with
polypropylene being the most preferred because it is somewhat
stronger than polyethylene. Fluorinated ethylene propylene has
suitable moisture absorption properties, but is not preferred
because of its cost, mechanical strength, and difficulty in
moulding. By contrast, the materials from which the piercer is
formed have much higher moisture absorption characteristics over a
24 hour period. For example, styrene-acrylonitrile absorbs about
0.2 to 0.35 percent moisture over a 24 hour period. Nylon absorbs
even more moisture, in the range of about 0.4 to 1.8 percent. The
polyvinyl chlorides are also unsuitable, absorbing from 0.2 to 1
percent by weight moisture over a 24 hour period.
Turning now to FIG. 3, piercer 12 defines parenteral fluid passage
48, having opening 50 in piercing member 26 for communicating with
the parenteral fluid container and discharge opening 52 in base 24
for communicating with drip chamber 20. Piercer 12 also includes
vent passage 54 for venting the parenteral fluid container. Vent
passage 54 includes longitudinally extending portion 56 which is
substantially parallel to parenteral fluid passage 48 and has
opening 58 in piercing member 26 for communicating with the
parenteral fluid container. Vent passage 54 also includss laterally
extending portion 60 having opening 62 in laterally extending
projection 30. Opening 62 is closed by air filter cap 32 for
filtering incoming air. It should be understood that vent passage
54 is only required in piercers for use with parenteral fluid
containers which do not have a separate vent tube. One end of drop
former 22 is inserted into discharge opening 52 in piercer 12 so
that tapered intermediate portion 40 forms a tight friction fit
therewith and annular shoulder 44 abuts the end of cylindrical
portion 36. Drop former 22 forms drops of predetermined size, which
function is normally provided by discharge opening 52 in piercer
12.
Turning now to FIG. 4, body 64 of drop former 22 defines parenteral
fluid passage 66 having opening 68 in top cylindrical portion 42
for communicating with parenteral fluid passage 48 in piercer 12.
Parenteral fluid passage 66 also has opening 70 in cylindrical base
portion 38 for communicating with drip chamber 20. Parenteral fluid
passage 66 includes cylindrical inlet and outlet portions 72 and
74, respectively. Cylindrical inlet portion 72 merges into
frusto-conical intermediate portion 76, which in turn merges into
tapered portion 78. The outlet end of tapered portion 78 merges
into the inlet end of cylindrical outlet portion 74. Parenteral
fluid passage 66 tapers outwardly from inlet opening 79 of
frusto-conical intermediate portion 76 to near outlet opening 70 so
that outlet opening 70 is of larger diameter than the inlet opening
79 of frusto-conical intermediate portion 76. Parenteral fluid
passage portions 74, 76 and 78 together form the drop forming
orifice of drop former 22. It is preferred that the ratio of the
length to outlet diameter of the drop forming orifice be at least
2:1 or, in other words, that the combined length of portions 74, 76
and 78 of parenteral fluid passage 66 be at least twice as long as
the diameter of outlet opening 70.
As illustrative of one embodiment of the present invention, drop
former 22 was formed from polypropylene having an overall length of
approximately one-half inch. Tapered intermediate portion 40 was
tapered outwardly at 1 1/4.degree. and inwardly tapered portion 46
was formed with an angle of 30.degree. with respect to a line drawn
perpendicular to the longitudinal centerline of drop former 22.
This taper forms sharp circular edge 80 which facilitates the
formation of the drops. In this embodiment, inlet opening 68 had a
diameter of 0.032 inches and outlet opening 70 a diameter of 0.160
inches. Intermediate tapered portion 78 of parenteral fluid passage
66 was tapered at an angle of 4.degree. and frusto-conical section
76 was tapered at an angle of approximately 26.degree. . With this
arrangement, fifteen drops of parenteral fluid formed at outlet
opening 70 for each milliliter of parenteral fluid flowed
therethrough under standard intravenous set operating pressures.
Further, the drop size was found to remain constant even after
soaking the drop former overnight in 5 percent dextrose and
lactated Ringer's solution, respectively.
Referring now to FIGS. 5 and 6, drop former 22 is shown in use with
cannula 82, typically formed from stainless steel, which is used
for forming small drops suitable for measuring small flow rates
such as used in pediatric applications. In this arrangement,
cylindrical inlet portion 72 of parenteral fluid passage 66 forms a
sleeve into which cannula 82 is inserted. Cylindrical inlet portion
72 has a slightly smaller inner diameter than the outer diameter of
cannula 82, so that cannula 82 can be friction fitted in drop
former 22. Cannula 82 defines cylindrical passage 84, having inlet
opening 86 for communicating with parenteral fluid passage 48 in
piercer 12 and outlet opening 88 for communicating with drip
chamber 20. Outlet opening 88 is typically of suitable size for
forming 60 drops of parenteral fluid for each milliliter flowed
therethrough.
FIG. 7 shows a modified form of the drop former of the present
invention. Drop former 90 is shown inserted in parenteral fluid
discharge opening 92 in cylindrical projection 94 of the base 96 of
a piercer such as shown in FIG. 1. Drop former 90 includes
cylindrical base portion 98 and tapered top portion 100. Tapered
top portion 100 is of smaller diameter than cylindrical base
portion 98 forming annular shoulder 102 therebetween. Annular ring
collar 104 extends around top portion 100 of drop former 90 and is
adapted to contact the internal surface of parenteral fluid
discharge opening 108 when the bottom of cylindrical portion 94 of
the piercer contacts shoulder 102 of drop former 90. A typical
height for collar 104 would be approximately 0.004 inches.
Otherwise, drop former 90 is the same as drop former 22. As
previously mentioned, adhesive will not adhere to plastics such as
polypropylene which are used for forming the drop former of the
present invention, but it will adhere to plastics such as
styrene-acrylonitrile which are used in forming a piercer. In the
modified form of the drop former shown in FIG. 7, adhesive 109 can
be placed in annular opening 106 defined between annular projection
94 of the piercer and tapered top portion 100 of drop former 90.
The adhesive adheres to the inner surface of parenteral fluid
passage 108 of the piercer but does not adhere to the outer surface
of tapered top portion 100 of drop former 90. However, ring collar
104 forms a mechanical lock with adhesive 109, thereby preventing
drop former 90 from being inadvertently removed from parenteral
fluid passage 108.
As mentioned previously, it has been found that the size of the
drops formed at the drop forming orifice of a conventional piercer
formed from materials such as styrene-acrylonitrile, nylon, or
rigid polyvinyl chloride becomes larger with time, with up to 150
percent difference being noted over a 24 hour period. Also,
variations in drop size with time and with parenteral fluid flow
rate have been noted with respect to the plastic insert for
pediatric use discussed above which has a tapered parenteral fluid
passage which tapers inwardly from its inlet to its outlet forming
a passage of increasingly smaller diameter. While not desiring to
be limited by any particular theory, it is believed that the change
in drop size with time in the prior art piercers results from a
change in surface tension at the interface between the liquid and
plastic caused by a wetting of the surface, or possibly by an
expansion of the plastic due to water absorption. Further, it is
believed that the decrease in drop size at higher flow rates found
in the plastic pediatric insert is caused by insufficient viscous
drag to overcome the parenteral fluid inertia, which inertia
increases with the flow rate. These problems of the prior art are
solved by the use of the drop former of the present invention which
is formed from the plastic which absorbs less than about 0.03
percent by weight water, so that water absorption and surface
wetting are substantially avoided. Also, the viscous drag problems
are solved by providing a drop former having a straight or
outwardly tapered flow passage.
While one or more specific embodiments of the present invention
have been illustrated, it will be understood that there are other
embodiments falling within the scope of the present invention. For
example, the cylindrical inlet portion of the parenteral fluid
passage of the drop former can be dispensed with when it is not
desired to adapt the drop former for pediatric use, such as by
insertion of a stainless steel cannula. Also, the general exterior
shape of the drop former can be varied to adapt it for use in
combination with various size and shape discharge openings in
conventional piercers.
* * * * *