U.S. patent application number 16/270067 was filed with the patent office on 2019-05-23 for immunogenic compositions for the prevention and treatment of meningococcal disease. The applicant listed for this patent is Wyeth Holdings LLC. Invention is credited to Liesel A. Bernfield, John E. Farley, Leah D. Fletcher, Benjamin J. Metcalf, Robert J. Zagursky, Gary W. Zlotnick.
Application Number | 20190151431 16/270067 |
Document ID | / |
Family ID | 27668840 |
Filed Date | 2019-05-23 |
United States Patent Application | 20190151431 |
Kind Code | A1 |
Zlotnick; Gary W. ; et al. | May 23, 2019 |
The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
Inventors: | Zlotnick; Gary W.; (San Antonio, TX) ; Fletcher; Leah D.; (Geneseo, NY) ; Farley; John E.; (Chapel Hill, NC) ; Bernfield; Liesel A.; (Rochester, NY) ; Zagursky; Robert J.; (Victor, NY) ; Metcalf; Benjamin J.; (Rochester, NY) | ||||||||||
Applicant: |
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Family ID: | 27668840 | ||||||||||
Appl. No.: | 16/270067 | ||||||||||
Filed: | February 7, 2019 |
Application Number | Filing Date | Patent Number | ||
---|---|---|---|---|
15443618 | Feb 27, 2017 | |||
16270067 | ||||
13455326 | Apr 25, 2012 | 9623101 | ||
15443618 | ||||
13333123 | Dec 21, 2011 | 8563006 | ||
13455326 | ||||
10492427 | Oct 7, 2004 | 8101194 | ||
PCT/US02/32369 | Oct 11, 2002 | |||
13333123 | ||||
60406934 | Aug 30, 2002 | |||
60328101 | Oct 11, 2001 | |||
Current U.S. Class: | 1/1 |
Current CPC Class: | C12N 9/2417 20130101; A61K 2039/55572 20130101; A61K 2039/505 20130101; G01N 2333/22 20130101; A61K 2039/53 20130101; G01N 33/56911 20130101; A61K 2039/55505 20130101; A61K 2039/6087 20130101; C07K 14/22 20130101; A61K 39/095 20130101; A61K 39/00 20130101; A61K 2039/55577 20130101; A61P 37/04 20180101; Y10S 530/825 20130101; A61K 2039/54 20130101; C07K 16/1217 20130101; A61K 47/543 20170801; A61K 2039/58 20130101; A61K 47/646 20170801; A61K 39/39 20130101; A61P 25/00 20180101; A61P 31/04 20180101; C12N 9/2471 20130101; C12N 9/2465 20130101 |
International Class: | A61K 39/095 20060101 A61K039/095; A61K 39/39 20060101 A61K039/39; A61K 47/64 20060101 A61K047/64; C12N 9/28 20060101 C12N009/28; C12N 9/40 20060101 C12N009/40; G01N 33/569 20060101 G01N033/569; A61K 47/54 20060101 A61K047/54; C07K 14/22 20060101 C07K014/22; C07K 16/12 20060101 C07K016/12; C12N 9/38 20060101 C12N009/38 |
Sequence CWU 1
1
3291765DNANeisseria meningitidis 1tgcagcagcg gaggcggcgg tgtcgccgcc
gacatcggcg cggggcttgc cgatgcacta 60accacaccgc tcgaccataa agacaaaagt
ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa
gctggcggca caaggtgcgg aaaaaactta tggaaacggc 180gacagcctca
atacgggcaa attgaagaac gacaaggtca gccgcttcga ctttatccgt
240caaatcgaag tggacggaca aaccatcacg ctggcaagcg gcgaatttca
aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag attgaaaaaa
tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg ctccttcctt
gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac tgcctgacgg
caaagccgag tatcacggca aagcattcag ctccgacgac 480ccgaacggca
ggctgcacta ctccattgat tttaccaaaa aacagggtta cggcagaatc
540gaacacctga aaacgcccga gcagaatgtc gagcttgcct ccgccgaact
caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac acgcgctacg
gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg cgaccgcgcc
caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa aggttcacga
aatcggcatc gccggcaaac agtag 7652254PRTNeisseria meningitidis 2Cys
Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10
15Ala Asp Ala Leu Thr Thr Pro Leu Asp His Lys Asp Lys Ser Leu Gln
20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys
Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser
Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp
Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Thr Ile Thr Leu
Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn His Ser Ala Val
Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile
Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu
Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys
Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Pro
Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr Lys Lys Gln Gly 165 170
175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu
180 185 190Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val
Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr
Tyr His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala
Gly Ser Ala Thr Val Lys225 230 235 240Ile Arg Glu Lys Val His Glu
Ile Gly Ile Ala Gly Lys Gln 245 2503768DNANeisseria meningitidis
3tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca
60ctaaccacac cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg acaaaccatc
acgctggcaa gcggcgaatt tcaaatatac 300aaacagaacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gacccgaacg gcaggctgca ctactccatt gattttacca
aaaaacaggg ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat
gtcgagcttg cctccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcggcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagataaggg aaaaggttca cgaaatcggc atcgccggca aacagtag
7684255PRTNeisseria meningitidis 4Cys Gly Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Thr
Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln
Ile Glu Val Asp Gly Gln Thr Ile Thr Leu Ala Ser Gly Glu 85 90 95Phe
Gln Ile Tyr Lys Gln Asn His Ser Ala Val Val Ala Leu Gln Ile 100 105
110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg
115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe
Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala
Phe Ser Ser Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser
Ile Asp Phe Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His
Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp
Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala
Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230
235 240Lys Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln
245 250 2555765DNANeisseria meningitidis 5atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accacaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 7656254PRTNeisseria
meningitidis 6Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Thr Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Thr Ile Thr Leu Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
2507765DNANeisseria meningitidis 7tgcagcagcg gaggcggcgg tgtcgccgcc
gacatcggcg cggggcttgc cgatgcacta 60accacaccgc tcgaccataa agacaaaagt
ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa
gctggcggca caaggtgcgg aaaaaactta tggaaacggc 180gacagcctca
atacgggcaa attgaagaac gacaaggtca gccgcttcga ctttatccgt
240caaatcgaag tggacggaca aaccatcacg ctggcaagcg gcgaatttca
aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag attgaaaaaa
tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg ctccttcctt
gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac tgcctgacgg
caaagccgag tatcacggca aagcattcag ctccgacgac 480ccgaacggca
ggctgcacta ctccattgat tttaccaaaa aacagggtta cggcagaatc
540gaacacctga aaacgcccga gcagaatgtc gagcttgcct ccgccgaact
caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac acgcgctacg
gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg cgaccgcgcc
caagaaatcg ccggcccggc aaccgtgaag 720ataagggaaa aggttcacga
aatcggcatc gccagcaaac agtag 7658254PRTNeisseria meningitidis 8Cys
Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10
15Ala Asp Ala Leu Thr Thr Pro Leu Asp His Lys Asp Lys Ser Leu Gln
20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys
Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser
Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp
Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Thr Ile Thr Leu
Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn His Ser Ala Val
Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile
Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu
Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys
Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Pro
Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr Lys Lys Gln Gly 165 170
175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu
180 185 190Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val
Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr
Tyr His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala
Gly Pro Ala Thr Val Lys225 230 235 240Ile Arg Glu Lys Val His Glu
Ile Gly Ile Ala Ser Lys Gln 245 2509768DNANeisseria meningitidis
9tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca
60ctaaccacac cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg acaaaccatc
acgctggcaa gcggcgaatt tcaaatatac 300aaacagaacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gacccgaacg gcaggctgca ctactccatt gattttacca
aaaaacaggg ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat
gtcgagcttg cctccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcggcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggccc ggcaaccgtg
720aagataaggg aaaaggttca cgaaatcggc atcgccagca aacagtag
76810255PRTNeisseria meningitidis 10Cys Gly Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Thr
Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln
Ile Glu Val Asp Gly Gln Thr Ile Thr Leu Ala Ser Gly Glu 85 90 95Phe
Gln Ile Tyr Lys Gln Asn His Ser Ala Val Val Ala Leu Gln Ile 100 105
110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg
115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe
Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala
Phe Ser Ser Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser
Ile Asp Phe Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His
Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp
Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala
Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Pro Ala Thr Val225 230
235 240Lys Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Ser Lys Gln
245 250 25511765DNANeisseria meningitidis 11atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accacaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggcccggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccagcaaac agtag 76512254PRTNeisseria
meningitidis 12Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Thr Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Thr Ile Thr Leu Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Pro Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Ser Lys Gln 245
25013765DNANeisseria meningitidis 13tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcggag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc
gccggcaaac agtag 76514254PRTNeisseria meningitidis 14Cys Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser
Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40
45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn
50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile
Arg65 70 75 80Gln Ile Gly Val Asp Gly Gln Thr Ile Thr Leu Ala Ser
Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn His Ser Ala Val Val Ala
Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser
Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly
Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu
Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Pro Asn Gly
Arg Leu His Tyr Ser Ile Asp Phe Thr Lys Lys Gln Gly 165 170 175Tyr
Gly Arg Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185
190Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu
195 200 205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His
Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser
Ala Thr Val Lys225 230 235 240Ile Arg Glu Lys Val His Glu Ile Gly
Ile Ala Gly Lys Gln 245 25015768DNANeisseria meningitidis
15tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca
60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg gagtggacgg acaaaccatc
acgctggcaa gcggcgaatt tcaaatatac 300aaacagaacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gacccgaacg gcaggctgca ctactccatt gattttacca
aaaaacaggg ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat
gtcgagcttg cctccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcggcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagataaggg aaaaggttca cgaaatcggc atcgccggca aacagtag
76816255PRTNeisseria meningitidis 16Cys Gly Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln
Ile Gly Val Asp Gly Gln Thr Ile Thr Leu Ala Ser Gly Glu 85 90 95Phe
Gln Ile Tyr Lys Gln Asn His Ser Ala Val Val Ala Leu Gln Ile 100 105
110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg
115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe
Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala
Phe Ser Ser Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser
Ile Asp Phe Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His
Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp
Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala
Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230
235 240Lys Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln
245 250 25517765DNANeisseria meningitidis 17atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcggag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76518254PRTNeisseria
meningitidis 18Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Gly Val Asp Gly Gln
Thr Ile Thr Leu Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25019765DNANeisseria meningitidis 19tgcagcagca gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76520254PRTNeisseria
meningitidis 20Cys Ser Ser Arg Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Thr Ile Thr Leu Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25021768DNANeisseria meningitidis 21tgcggatcca gcagaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg acaaaccatc acgctggcaa
gcggcgaatt tcaaatatac 300aaacagaacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggcgg agaacatacc 420gccttcaacc
aactgcctga cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gacccgaacg gcaggctgca ctactccatt gattttacca aaaaacaggg
ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76822255PRTNeisseria
meningitidis 22Cys Gly Ser Ser Arg Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Thr Ile Thr Leu Ala Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asn His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe
Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25523765DNANeisseria meningitidis 23atgagcagca gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacggaca aaccatcacg ctggcaagcg
gcgaatttca aatatacaaa 300cagaaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76524254PRTNeisseria
meningitidis 24Met Ser Ser Arg Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Thr Ile Thr Leu Ala Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asn
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25025765DNANeisseria meningitidis 25tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgt tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76526254PRTNeisseria
meningitidis 26Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Phe Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile
Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His
Thr Ala Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His
Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Pro Asn Gly Arg Leu
His Tyr Ser Ile Asp Phe Thr Lys Lys Gln Gly 165 170 175Tyr Gly Arg
Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala
Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200
205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu Ala
210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val Lys225 230 235 240Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 25027768DNANeisseria meningitidis 27tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgttcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggtgg agaacatacc
420gccttcaacc aactgcccag cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gacccgaacg gcaggctgca ctactccatt gattttacca
aaaaacaggg ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat
gtcgagcttg cctccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcggcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagataaggg aaaaggttca cgaaatcggc atcgccggca aacagtag
76828255PRTNeisseria meningitidis 28Cys Gly Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala
Pro Phe Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe
Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105
110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg
115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe
Asn Gln 130 135 140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala
Phe Ser Ser Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser
Ile Asp Phe Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His
Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp
Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala
Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230
235 240Lys Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln
245 250 25529765DNANeisseria meningitidis 29atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgt tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76530254PRTNeisseria
meningitidis 30Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Phe Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25031765DNANeisseria meningitidis 31tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76532254PRTNeisseria
meningitidis 32Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25033768DNANeisseria meningitidis 33tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gacccgaacg gcaggctgca ctactccatt gattttacca aaaaacaggg
ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76834255PRTNeisseria
meningitidis 34Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe
Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25535765DNANeisseria meningitidis 35atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76536254PRTNeisseria
meningitidis 36Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25037765DNANeisseria meningitidis 37tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76538254PRTNeisseria
meningitidis 38Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln
245 25039768DNANeisseria meningitidis 39tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gacccgaacg gcaggctgca ctactccatt gattttacca aaaaacaggg
ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76840255PRTNeisseria
meningitidis 40Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe
Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25541765DNANeisseria meningitidis 41atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76542254PRTNeisseria
meningitidis 42Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25043765DNANeisseria meningitidis 43tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76544254PRTNeisseria
meningitidis 44Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25045768DNANeisseria meningitidis 45tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gacccgaacg gcaggctgca ctactccatt gattttacca aaaaacaggg
ttacggcaga 540atcgaacacc tgaaaacgcc cgagcagaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76846255PRTNeisseria
meningitidis 46Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe
Thr Lys Lys Gln 165 170 175Gly Tyr Gly Arg Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25547765DNANeisseria meningitidis 47atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgac
480ccgaacggca ggctgcacta ctccattgat tttaccaaaa aacagggtta
cggcagaatc 540gaacacctga aaacgcccga gcagaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76548254PRTNeisseria
meningitidis 48Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Pro Asn Gly Arg Leu His Tyr Ser Ile Asp Phe Thr
Lys Lys Gln Gly 165 170 175Tyr Gly Arg Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25049786DNANeisseria meningitidis 49tgcagcagcg gaagcggaag
cggaggcggc ggtgtcgccg ccgacatcgg cacagggctt 60gccgatgcac taactgcgcc
gctcgaccat aaagacaaag gtttgaaatc cctgacattg 120gaagactcca
tttcccaaaa cggaacactg accctgtcgg cacaaggtgc ggaaaaaact
180ttcaaagtcg gcgacaaaga caacagtctc aatacaggca aattgaagaa
cgacaaaatc 240agccgcttcg actttgtgca aaaaatcgaa gtggacggac
aaaccatcac gctggcaagc 300ggcgaatttc aaatatacaa acaggaccac
tccgccgtcg ttgccctaca gattgaaaaa 360atcaacaacc ccgacaaaat
cgacagcctg ataaaccaac gctccttcct tgtcagcggt 420ttgggcggag
aacataccgc cttcaaccaa ctgcccagcg gcaaagccga gtatcacggc
480aaagcattca gctccgacga tgccggcgga aaactgacct ataccataga
ttttgccgcc 540aaacagggac acggcaaaat cgaacacctg aaaacacccg
agcagaatgt cgagcttgcc 600tccgccgaac tcaaagcaga tgaaaaatca
cacgccgtca ttttgggcga cacgcgctac 660ggcagcgaag aaaaaggcac
ttaccacctc gctcttttcg gcgaccgagc ccaagaaatc 720gccggctcgg
caaccgtgaa gataagggaa aaggttcacg aaatcggcat cgccggcaaa 780cagtag
78650261PRTNeisseria meningitidis 50Cys Ser Ser Gly Ser Gly Ser Gly
Gly Gly Gly Val Ala Ala Asp Ile1 5 10 15Gly Thr Gly Leu Ala Asp Ala
Leu Thr Ala Pro Leu Asp His Lys Asp 20 25 30Lys Gly Leu Lys Ser Leu
Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly 35 40 45Thr Leu Thr Leu Ser
Ala Gln Gly Ala Glu Lys Thr Phe Lys Val Gly 50 55 60Asp Lys Asp Asn
Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys Ile65 70 75 80Ser Arg
Phe Asp Phe Val Gln Lys Ile Glu Val Asp Gly Gln Thr Ile 85 90 95Thr
Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys Gln Asp His Ser Ala 100 105
110Val Val Ala Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp
115 120 125Ser Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu Gly
Gly Glu 130 135 140His Thr Ala Phe Asn Gln Leu Pro Ser Gly Lys Ala
Glu Tyr His Gly145 150 155 160Lys Ala Phe Ser Ser Asp Asp Ala Gly
Gly Lys Leu Thr Tyr Thr Ile 165 170 175Asp Phe Ala Ala Lys Gln Gly
His Gly Lys Ile Glu His Leu Lys Thr 180 185 190Pro Glu Gln Asn Val
Glu Leu Ala Ser Ala Glu Leu Lys Ala Asp Glu 195 200 205Lys Ser His
Ala Val Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu Glu 210 215 220Lys
Gly Thr Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile225 230
235 240Ala Gly Ser Ala Thr Val Lys Ile Arg Glu Lys Val His Glu Ile
Gly 245 250 255Ile Ala Gly Lys Gln 26051789DNANeisseria
meningitidis 51tgcggatcca gcggaagcgg aagcggaggc ggcggtgtcg
ccgccgacat cggcacaggg 60cttgccgatg cactaactgc gccgctcgac cataaagaca
aaggtttgaa atccctgaca 120ttggaagact ccatttccca aaacggaaca
ctgaccctgt cggcacaagg tgcggaaaaa 180actttcaaag tcggcgacaa
agacaacagt ctcaatacag gcaaattgaa gaacgacaaa 240atcagccgct
tcgactttgt gcaaaaaatc gaagtggacg gacaaaccat cacgctggca
300agcggcgaat ttcaaatata caaacaggac cactccgccg tcgttgccct
acagattgaa 360aaaatcaaca accccgacaa aatcgacagc ctgataaacc
aacgctcctt ccttgtcagc 420ggtttgggcg gagaacatac cgccttcaac
caactgccca gcggcaaagc cgagtatcac 480ggcaaagcat tcagctccga
cgatgccggc ggaaaactga cctataccat agattttgcc 540gccaaacagg
gacacggcaa aatcgaacac ctgaaaacac ccgagcagaa tgtcgagctt
600gcctccgccg
aactcaaagc agatgaaaaa tcacacgccg tcattttggg cgacacgcgc
660tacggcagcg aagaaaaagg cacttaccac ctcgctcttt tcggcgaccg
agcccaagaa 720atcgccggct cggcaaccgt gaagataagg gaaaaggttc
acgaaatcgg catcgccggc 780aaacagtag 78952262PRTNeisseria
meningitidis 52Cys Gly Ser Ser Gly Ser Gly Ser Gly Gly Gly Gly Val
Ala Ala Asp1 5 10 15Ile Gly Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro
Leu Asp His Lys 20 25 30Asp Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp
Ser Ile Ser Gln Asn 35 40 45Gly Thr Leu Thr Leu Ser Ala Gln Gly Ala
Glu Lys Thr Phe Lys Val 50 55 60Gly Asp Lys Asp Asn Ser Leu Asn Thr
Gly Lys Leu Lys Asn Asp Lys65 70 75 80Ile Ser Arg Phe Asp Phe Val
Gln Lys Ile Glu Val Asp Gly Gln Thr 85 90 95Ile Thr Leu Ala Ser Gly
Glu Phe Gln Ile Tyr Lys Gln Asp His Ser 100 105 110Ala Val Val Ala
Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile 115 120 125Asp Ser
Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu Gly Gly 130 135
140Glu His Thr Ala Phe Asn Gln Leu Pro Ser Gly Lys Ala Glu Tyr
His145 150 155 160Gly Lys Ala Phe Ser Ser Asp Asp Ala Gly Gly Lys
Leu Thr Tyr Thr 165 170 175Ile Asp Phe Ala Ala Lys Gln Gly His Gly
Lys Ile Glu His Leu Lys 180 185 190Thr Pro Glu Gln Asn Val Glu Leu
Ala Ser Ala Glu Leu Lys Ala Asp 195 200 205Glu Lys Ser His Ala Val
Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu 210 215 220Glu Lys Gly Thr
Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu225 230 235 240Ile
Ala Gly Ser Ala Thr Val Lys Ile Arg Glu Lys Val His Glu Ile 245 250
255Gly Ile Ala Gly Lys Gln 26053786DNANeisseria meningitidis
53atgagcagcg gaagcggaag cggaggcggc ggtgtcgccg ccgacatcgg cacagggctt
60gccgatgcac taactgcgcc gctcgaccat aaagacaaag gtttgaaatc cctgacattg
120gaagactcca tttcccaaaa cggaacactg accctgtcgg cacaaggtgc
ggaaaaaact 180ttcaaagtcg gcgacaaaga caacagtctc aatacaggca
aattgaagaa cgacaaaatc 240agccgcttcg actttgtgca aaaaatcgaa
gtggacggac aaaccatcac gctggcaagc 300ggcgaatttc aaatatacaa
acaggaccac tccgccgtcg ttgccctaca gattgaaaaa 360atcaacaacc
ccgacaaaat cgacagcctg ataaaccaac gctccttcct tgtcagcggt
420ttgggcggag aacataccgc cttcaaccaa ctgcccagcg gcaaagccga
gtatcacggc 480aaagcattca gctccgacga tgccggcgga aaactgacct
ataccataga ttttgccgcc 540aaacagggac acggcaaaat cgaacacctg
aaaacacccg agcagaatgt cgagcttgcc 600tccgccgaac tcaaagcaga
tgaaaaatca cacgccgtca ttttgggcga cacgcgctac 660ggcagcgaag
aaaaaggcac ttaccacctc gctcttttcg gcgaccgagc ccaagaaatc
720gccggctcgg caaccgtgaa gataagggaa aaggttcacg aaatcggcat
cgccggcaaa 780cagtag 78654261PRTNeisseria meningitidis 54Met Ser
Ser Gly Ser Gly Ser Gly Gly Gly Gly Val Ala Ala Asp Ile1 5 10 15Gly
Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp 20 25
30Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly
35 40 45Thr Leu Thr Leu Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Val
Gly 50 55 60Asp Lys Asp Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp
Lys Ile65 70 75 80Ser Arg Phe Asp Phe Val Gln Lys Ile Glu Val Asp
Gly Gln Thr Ile 85 90 95Thr Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys
Gln Asp His Ser Ala 100 105 110Val Val Ala Leu Gln Ile Glu Lys Ile
Asn Asn Pro Asp Lys Ile Asp 115 120 125Ser Leu Ile Asn Gln Arg Ser
Phe Leu Val Ser Gly Leu Gly Gly Glu 130 135 140His Thr Ala Phe Asn
Gln Leu Pro Ser Gly Lys Ala Glu Tyr His Gly145 150 155 160Lys Ala
Phe Ser Ser Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile 165 170
175Asp Phe Ala Ala Lys Gln Gly His Gly Lys Ile Glu His Leu Lys Thr
180 185 190Pro Glu Gln Asn Val Glu Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu 195 200 205Lys Ser His Ala Val Ile Leu Gly Asp Thr Arg Tyr
Gly Ser Glu Glu 210 215 220Lys Gly Thr Tyr His Leu Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile225 230 235 240Ala Gly Ser Ala Thr Val Lys
Ile Arg Glu Lys Val His Glu Ile Gly 245 250 255Ile Ala Gly Lys Gln
26055786DNANeisseria meningitidis 55tgcagcagcg gaagcggaag
cggaggcggc ggtgtcgccg ccgacatcgg cacagggctt 60gccgatgcac taactgcgcc
gctcgaccat aaagacaaag gtttgaaatc cctgacattg 120gaagactcca
tttcccaaaa cggaacactg accctgtcgg cacaaggtgc ggaaaaaact
180ttcaaagtcg gcgacaaaga caacagtctc aatacaggca aattgaagaa
cgacaaaatc 240agccgcttcg actttgtgca aaaaatcgaa gtggacggac
aaaccatcac gctggcaagc 300ggcgaatttc aaatatacaa acaggaccac
tccgccgtcg ttgccctaca gattgaaaaa 360atcaacaacc ccgacaaaat
cgacagcctg ataaaccaac gctccttcct tgtcagcggt 420ttgggcggag
aacataccgc cttcaaccaa ctgcccagcg gcaaagccga gtatcacggc
480aaagcattca gctccgacga tgccggcgga aaactgacct ataccataga
ttttgccgcc 540aaacagggac acggcaaaat cgaacacctg aaaacacccg
agcagaatgt cgagcttgcc 600tccgccgaac tcaaagcaga tgaaaaatca
cacgccgtca ttttgggcga cacgcgctac 660ggcagcgaag aaaaaggcac
ttaccacctc gctcttttcg gcgaccgagc ccaagaaatc 720gccggctcgg
caaccgtgaa gataagggaa aaggttcacg aaatcggcat cgccggcaaa 780cagtag
78656261PRTNeisseria meningitidis 56Cys Ser Ser Gly Ser Gly Ser Gly
Gly Gly Gly Val Ala Ala Asp Ile1 5 10 15Gly Thr Gly Leu Ala Asp Ala
Leu Thr Ala Pro Leu Asp His Lys Asp 20 25 30Lys Gly Leu Lys Ser Leu
Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly 35 40 45Thr Leu Thr Leu Ser
Ala Gln Gly Ala Glu Lys Thr Phe Lys Val Gly 50 55 60Asp Lys Asp Asn
Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys Ile65 70 75 80Ser Arg
Phe Asp Phe Val Gln Lys Ile Glu Val Asp Gly Gln Thr Ile 85 90 95Thr
Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys Gln Asp His Ser Ala 100 105
110Val Val Ala Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp
115 120 125Ser Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu Gly
Gly Glu 130 135 140His Thr Ala Phe Asn Gln Leu Pro Ser Gly Lys Ala
Glu Tyr His Gly145 150 155 160Lys Ala Phe Ser Ser Asp Asp Ala Gly
Gly Lys Leu Thr Tyr Thr Ile 165 170 175Asp Phe Ala Ala Lys Gln Gly
His Gly Lys Ile Glu His Leu Lys Thr 180 185 190Pro Glu Gln Asn Val
Glu Leu Ala Ser Ala Glu Leu Lys Ala Asp Glu 195 200 205Lys Ser His
Ala Val Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu Glu 210 215 220Lys
Gly Thr Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile225 230
235 240Ala Gly Ser Ala Thr Val Lys Ile Arg Glu Lys Val His Glu Ile
Gly 245 250 255Ile Ala Gly Lys Gln 26057789DNANeisseria
meningitidis 57tgcggatcca gcggaagcgg aagcggaggc ggcggtgtcg
ccgccgacat cggcacaggg 60cttgccgatg cactaactgc gccgctcgac cataaagaca
aaggtttgaa atccctgaca 120ttggaagact ccatttccca aaacggaaca
ctgaccctgt cggcacaagg tgcggaaaaa 180actttcaaag tcggcgacaa
agacaacagt ctcaatacag gcaaattgaa gaacgacaaa 240atcagccgct
tcgactttgt gcaaaaaatc gaagtggacg gacaaaccat cacgctggca
300agcggcgaat ttcaaatata caaacaggac cactccgccg tcgttgccct
acagattgaa 360aaaatcaaca accccgacaa aatcgacagc ctgataaacc
aacgctcctt ccttgtcagc 420ggtttgggcg gagaacatac cgccttcaac
caactgccca gcggcaaagc cgagtatcac 480ggcaaagcat tcagctccga
cgatgccggc ggaaaactga cctataccat agattttgcc 540gccaaacagg
gacacggcaa aatcgaacac ctgaaaacac ccgagcagaa tgtcgagctt
600gcctccgccg aactcaaagc agatgaaaaa tcacacgccg tcattttggg
cgacacgcgc 660tacggcagcg aagaaaaagg cacttaccac ctcgctcttt
tcggcgaccg agcccaagaa 720atcgccggct cggcaaccgt gaagataagg
gaaaaggttc acgaaatcgg catcgccggc 780aaacagtag 78958262PRTNeisseria
meningitidis 58Cys Gly Ser Ser Gly Ser Gly Ser Gly Gly Gly Gly Val
Ala Ala Asp1 5 10 15Ile Gly Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro
Leu Asp His Lys 20 25 30Asp Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp
Ser Ile Ser Gln Asn 35 40 45Gly Thr Leu Thr Leu Ser Ala Gln Gly Ala
Glu Lys Thr Phe Lys Val 50 55 60Gly Asp Lys Asp Asn Ser Leu Asn Thr
Gly Lys Leu Lys Asn Asp Lys65 70 75 80Ile Ser Arg Phe Asp Phe Val
Gln Lys Ile Glu Val Asp Gly Gln Thr 85 90 95Ile Thr Leu Ala Ser Gly
Glu Phe Gln Ile Tyr Lys Gln Asp His Ser 100 105 110Ala Val Val Ala
Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile 115 120 125Asp Ser
Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu Gly Gly 130 135
140Glu His Thr Ala Phe Asn Gln Leu Pro Ser Gly Lys Ala Glu Tyr
His145 150 155 160Gly Lys Ala Phe Ser Ser Asp Asp Ala Gly Gly Lys
Leu Thr Tyr Thr 165 170 175Ile Asp Phe Ala Ala Lys Gln Gly His Gly
Lys Ile Glu His Leu Lys 180 185 190Thr Pro Glu Gln Asn Val Glu Leu
Ala Ser Ala Glu Leu Lys Ala Asp 195 200 205Glu Lys Ser His Ala Val
Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu 210 215 220Glu Lys Gly Thr
Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu225 230 235 240Ile
Ala Gly Ser Ala Thr Val Lys Ile Arg Glu Lys Val His Glu Ile 245 250
255Gly Ile Ala Gly Lys Gln 26059786DNANeisseria meningitidis
59atgagcagcg gaagcggaag cggaggcggc ggtgtcgccg ccgacatcgg cacagggctt
60gccgatgcac taactgcgcc gctcgaccat aaagacaaag gtttgaaatc cctgacattg
120gaagactcca tttcccaaaa cggaacactg accctgtcgg cacaaggtgc
ggaaaaaact 180ttcaaagtcg gcgacaaaga caacagtctc aatacaggca
aattgaagaa cgacaaaatc 240agccgcttcg actttgtgca aaaaatcgaa
gtggacggac aaaccatcac gctggcaagc 300ggcgaatttc aaatatacaa
acaggaccac tccgccgtcg ttgccctaca gattgaaaaa 360atcaacaacc
ccgacaaaat cgacagcctg ataaaccaac gctccttcct tgtcagcggt
420ttgggcggag aacataccgc cttcaaccaa ctgcccagcg gcaaagccga
gtatcacggc 480aaagcattca gctccgacga tgccggcgga aaactgacct
ataccataga ttttgccgcc 540aaacagggac acggcaaaat cgaacacctg
aaaacacccg agcagaatgt cgagcttgcc 600tccgccgaac tcaaagcaga
tgaaaaatca cacgccgtca ttttgggcga cacgcgctac 660ggcagcgaag
aaaaaggcac ttaccacctc gctcttttcg gcgaccgagc ccaagaaatc
720gccggctcgg caaccgtgaa gataagggaa aaggttcacg aaatcggcat
cgccggcaaa 780cagtag 78660261PRTNeisseria meningitidis 60Met Ser
Ser Gly Ser Gly Ser Gly Gly Gly Gly Val Ala Ala Asp Ile1 5 10 15Gly
Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp 20 25
30Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly
35 40 45Thr Leu Thr Leu Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Val
Gly 50 55 60Asp Lys Asp Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp
Lys Ile65 70 75 80Ser Arg Phe Asp Phe Val Gln Lys Ile Glu Val Asp
Gly Gln Thr Ile 85 90 95Thr Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys
Gln Asp His Ser Ala 100 105 110Val Val Ala Leu Gln Ile Glu Lys Ile
Asn Asn Pro Asp Lys Ile Asp 115 120 125Ser Leu Ile Asn Gln Arg Ser
Phe Leu Val Ser Gly Leu Gly Gly Glu 130 135 140His Thr Ala Phe Asn
Gln Leu Pro Ser Gly Lys Ala Glu Tyr His Gly145 150 155 160Lys Ala
Phe Ser Ser Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile 165 170
175Asp Phe Ala Ala Lys Gln Gly His Gly Lys Ile Glu His Leu Lys Thr
180 185 190Pro Glu Gln Asn Val Glu Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu 195 200 205Lys Ser His Ala Val Ile Leu Gly Asp Thr Arg Tyr
Gly Ser Glu Glu 210 215 220Lys Gly Thr Tyr His Leu Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile225 230 235 240Ala Gly Ser Ala Thr Val Lys
Ile Arg Glu Lys Val His Glu Ile Gly 245 250 255Ile Ala Gly Lys Gln
26061789DNANeisseria meningitidis 61tgcagcagcg gaggcggcgg
aagcggaggc ggcggtgtcg ccgccgacat cggcacgggg 60cttgccgatg cactaactgc
gccgctcgac cataaagaca aaggtttgaa atccctgaca 120ttggaagact
ctattcccca aaacggaaca ctaaccctgt cggcacaagg tgcggaaaaa
180actttcaaag ccggcgacaa agacaacagc ctcaacacgg gcaaactgaa
gaacgacaaa 240atcagccgct tcgactttgt gcaaaaaatc gaagtggacg
gacaaaccat cacgctggca 300agcggcgaat ttcaaatata caaacaggac
cactccgccg tcgttgccct acagattgaa 360aaaatcaaca accccgacaa
aatcgacagc ctgataaacc aacgctcctt ccttgtcagc 420ggtttgggcg
gagaacatac cgccttcaac caactgcccg gcggcaaagc cgagtatcac
480ggcaaagcat tcagctccga cgacccgaac ggcaggctgc actactccat
tgattttacc 540aaaaaacagg gttacggcgg aatcgaacac ctgaaaacac
ccgagcaaaa tgtcgagctt 600gcctccgccg aactcaaagc agatgaaaaa
tcacacgccg tcattttggg cgacacgcgc 660tacggcagcg aagaaaaagg
cacttaccac ctcgcccttt tcggcgaccg cgcccaagaa 720atcgccggct
cggcaaccgt gaagataggg gaaaaggttc acgaaatcgg catcgccggc 780aaacagtag
78962262PRTNeisseria meningitidis 62Cys Ser Ser Gly Gly Gly Gly Ser
Gly Gly Gly Gly Val Ala Ala Asp1 5 10 15Ile Gly Thr Gly Leu Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys 20 25 30Asp Lys Gly Leu Lys Ser
Leu Thr Leu Glu Asp Ser Ile Pro Gln Asn 35 40 45Gly Thr Leu Thr Leu
Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Ala 50 55 60Gly Asp Lys Asp
Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys65 70 75 80Ile Ser
Arg Phe Asp Phe Val Gln Lys Ile Glu Val Asp Gly Gln Thr 85 90 95Ile
Thr Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys Gln Asp His Ser 100 105
110Ala Val Val Ala Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile
115 120 125Asp Ser Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu
Gly Gly 130 135 140Glu His Thr Ala Phe Asn Gln Leu Pro Gly Gly Lys
Ala Glu Tyr His145 150 155 160Gly Lys Ala Phe Ser Ser Asp Asp Pro
Asn Gly Arg Leu His Tyr Ser 165 170 175Ile Asp Phe Thr Lys Lys Gln
Gly Tyr Gly Gly Ile Glu His Leu Lys 180 185 190Thr Pro Glu Gln Asn
Val Glu Leu Ala Ser Ala Glu Leu Lys Ala Asp 195 200 205Glu Lys Ser
His Ala Val Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu 210 215 220Glu
Lys Gly Thr Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu225 230
235 240Ile Ala Gly Ser Ala Thr Val Lys Ile Gly Glu Lys Val His Glu
Ile 245 250 255Gly Ile Ala Gly Lys Gln 26063792DNANeisseria
meningitidis 63tgcggatcca gcggaggcgg cggaagcgga ggcggcggtg
tcgccgccga catcggcacg 60gggcttgccg atgcactaac tgcgccgctc gaccataaag
acaaaggttt gaaatccctg 120acattggaag actctattcc ccaaaacgga
acactaaccc tgtcggcaca aggtgcggaa 180aaaactttca aagccggcga
caaagacaac agcctcaaca cgggcaaact gaagaacgac 240aaaatcagcc
gcttcgactt tgtgcaaaaa atcgaagtgg acggacaaac catcacgctg
300gcaagcggcg aatttcaaat atacaaacag gaccactccg ccgtcgttgc
cctacagatt 360gaaaaaatca acaaccccga caaaatcgac agcctgataa
accaacgctc cttccttgtc 420agcggtttgg gcggagaaca taccgccttc
aaccaactgc ccggcggcaa agccgagtat 480cacggcaaag cattcagctc
cgacgacccg aacggcaggc tgcactactc cattgatttt 540accaaaaaac
agggttacgg cggaatcgaa cacctgaaaa cacccgagca aaatgtcgag
600cttgcctccg ccgaactcaa agcagatgaa aaatcacacg ccgtcatttt
gggcgacacg 660cgctacggca gcgaagaaaa aggcacttac cacctcgccc
ttttcggcga ccgcgcccaa 720gaaatcgccg
gctcggcaac cgtgaagata ggggaaaagg ttcacgaaat cggcatcgcc
780ggcaaacagt ag 79264263PRTNeisseria meningitidis 64Cys Gly Ser
Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Val Ala Ala1 5 10 15Asp Ile
Gly Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His 20 25 30Lys
Asp Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp Ser Ile Pro Gln 35 40
45Asn Gly Thr Leu Thr Leu Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys
50 55 60Ala Gly Asp Lys Asp Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn
Asp65 70 75 80Lys Ile Ser Arg Phe Asp Phe Val Gln Lys Ile Glu Val
Asp Gly Gln 85 90 95Thr Ile Thr Leu Ala Ser Gly Glu Phe Gln Ile Tyr
Lys Gln Asp His 100 105 110Ser Ala Val Val Ala Leu Gln Ile Glu Lys
Ile Asn Asn Pro Asp Lys 115 120 125Ile Asp Ser Leu Ile Asn Gln Arg
Ser Phe Leu Val Ser Gly Leu Gly 130 135 140Gly Glu His Thr Ala Phe
Asn Gln Leu Pro Gly Gly Lys Ala Glu Tyr145 150 155 160His Gly Lys
Ala Phe Ser Ser Asp Asp Pro Asn Gly Arg Leu His Tyr 165 170 175Ser
Ile Asp Phe Thr Lys Lys Gln Gly Tyr Gly Gly Ile Glu His Leu 180 185
190Lys Thr Pro Glu Gln Asn Val Glu Leu Ala Ser Ala Glu Leu Lys Ala
195 200 205Asp Glu Lys Ser His Ala Val Ile Leu Gly Asp Thr Arg Tyr
Gly Ser 210 215 220Glu Glu Lys Gly Thr Tyr His Leu Ala Leu Phe Gly
Asp Arg Ala Gln225 230 235 240Glu Ile Ala Gly Ser Ala Thr Val Lys
Ile Gly Glu Lys Val His Glu 245 250 255Ile Gly Ile Ala Gly Lys Gln
26065789DNANeisseria meningitidis 65atgagcagcg gaggcggcgg
aagcggaggc ggcggtgtcg ccgccgacat cggcacgggg 60cttgccgatg cactaactgc
gccgctcgac cataaagaca aaggtttgaa atccctgaca 120ttggaagact
ctattcccca aaacggaaca ctaaccctgt cggcacaagg tgcggaaaaa
180actttcaaag ccggcgacaa agacaacagc ctcaacacgg gcaaactgaa
gaacgacaaa 240atcagccgct tcgactttgt gcaaaaaatc gaagtggacg
gacaaaccat cacgctggca 300agcggcgaat ttcaaatata caaacaggac
cactccgccg tcgttgccct acagattgaa 360aaaatcaaca accccgacaa
aatcgacagc ctgataaacc aacgctcctt ccttgtcagc 420ggtttgggcg
gagaacatac cgccttcaac caactgcccg gcggcaaagc cgagtatcac
480ggcaaagcat tcagctccga cgacccgaac ggcaggctgc actactccat
tgattttacc 540aaaaaacagg gttacggcgg aatcgaacac ctgaaaacac
ccgagcaaaa tgtcgagctt 600gcctccgccg aactcaaagc agatgaaaaa
tcacacgccg tcattttggg cgacacgcgc 660tacggcagcg aagaaaaagg
cacttaccac ctcgcccttt tcggcgaccg cgcccaagaa 720atcgccggct
cggcaaccgt gaagataggg gaaaaggttc acgaaatcgg catcgccggc 780aaacagtag
78966262PRTNeisseria meningitidis 66Met Ser Ser Gly Gly Gly Gly Ser
Gly Gly Gly Gly Val Ala Ala Asp1 5 10 15Ile Gly Thr Gly Leu Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys 20 25 30Asp Lys Gly Leu Lys Ser
Leu Thr Leu Glu Asp Ser Ile Pro Gln Asn 35 40 45Gly Thr Leu Thr Leu
Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Ala 50 55 60Gly Asp Lys Asp
Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys65 70 75 80Ile Ser
Arg Phe Asp Phe Val Gln Lys Ile Glu Val Asp Gly Gln Thr 85 90 95Ile
Thr Leu Ala Ser Gly Glu Phe Gln Ile Tyr Lys Gln Asp His Ser 100 105
110Ala Val Val Ala Leu Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile
115 120 125Asp Ser Leu Ile Asn Gln Arg Ser Phe Leu Val Ser Gly Leu
Gly Gly 130 135 140Glu His Thr Ala Phe Asn Gln Leu Pro Gly Gly Lys
Ala Glu Tyr His145 150 155 160Gly Lys Ala Phe Ser Ser Asp Asp Pro
Asn Gly Arg Leu His Tyr Ser 165 170 175Ile Asp Phe Thr Lys Lys Gln
Gly Tyr Gly Gly Ile Glu His Leu Lys 180 185 190Thr Pro Glu Gln Asn
Val Glu Leu Ala Ser Ala Glu Leu Lys Ala Asp 195 200 205Glu Lys Ser
His Ala Val Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu 210 215 220Glu
Lys Gly Thr Tyr His Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu225 230
235 240Ile Ala Gly Ser Ala Thr Val Lys Ile Gly Glu Lys Val His Glu
Ile 245 250 255Gly Ile Ala Gly Lys Gln 26067774DNANeisseria
meningitidis 67tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgaaatccc
tgacattgga agactccatt 120tcccaaaacg gaacactgac cctgtcggca
caaggtgcgg aaaaaacttt caaagtcggc 180gacaaagaca acagtctcaa
tacaggcaaa ttgaagaacg acaaaatcag ccgcttcgac 240tttgtgcaaa
aaatcgaagt ggacggacaa accatcacgc tggcaagcgg cgaatttcaa
300atatacaaac agaaccactc cgccgtcgtt gccctacaga ttgaaaaaat
caacaacccc 360gacaaaatcg acagcctgat aaaccaacgc tccttccttg
tcagcggttt gggcggagaa 420cataccgcct tcaaccaact gcccggcggc
aaagccgagt atcacggcaa agcattcagc 480tccgacgatg ccggcggaaa
actgacctat accatagatt ttgccgccaa acagggacac 540ggcaaaatcg
aacacctgaa aacacccgag caaaatgtcg agcttgccgc cgccgaactc
600aaagcagatg aaaaatcaca cgccgtcatt ttgggcgaca cgcgctacgg
cagcgaagaa 660aaaggcactt accacctcgc ccttttcggc gaccgcgctc
aagaaatcgc cggctcggca 720accgtgaaga taggagaaaa ggttcacgaa
atcagcatcg ccggcaaaca gtag 77468257PRTNeisseria meningitidis 68Cys
Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10
15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu Lys
20 25 30Ser Leu Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly Thr Leu Thr
Leu 35 40 45Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Val Gly Asp Lys
Asp Asn 50 55 60Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys Ile Ser
Arg Phe Asp65 70 75 80Phe Val Gln Lys Ile Glu Val Asp Gly Gln Thr
Ile Thr Leu Ala Ser 85 90 95Gly Glu Phe Gln Ile Tyr Lys Gln Asn His
Ser Ala Val Val Ala Leu 100 105 110Gln Ile Glu Lys Ile Asn Asn Pro
Asp Lys Ile Asp Ser Leu Ile Asn 115 120 125Gln Arg Ser Phe Leu Val
Ser Gly Leu Gly Gly Glu His Thr Ala Phe 130 135 140Asn Gln Leu Pro
Gly Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser145 150 155 160Ser
Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala 165 170
175Lys Gln Gly His Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn
180 185 190Val Glu Leu Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser
His Ala 195 200 205Val Ile Leu Gly Asp Thr Arg Tyr Gly Ser Glu Glu
Lys Gly Thr Tyr 210 215 220His Leu Ala Leu Phe Gly Asp Arg Ala Gln
Glu Ile Ala Gly Ser Ala225 230 235 240Thr Val Lys Ile Gly Glu Lys
Val His Glu Ile Ser Ile Ala Gly Lys 245 250 255Gln69777DNANeisseria
meningitidis 69tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg
gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa ggtttgaaat
ccctgacatt ggaagactcc 120atttcccaaa acggaacact gaccctgtcg
gcacaaggtg cggaaaaaac tttcaaagtc 180ggcgacaaag acaacagtct
caatacaggc aaattgaaga acgacaaaat cagccgcttc 240gactttgtgc
aaaaaatcga agtggacgga caaaccatca cgctggcaag cggcgaattt
300caaatataca aacagaacca ctccgccgtc gttgccctac agattgaaaa
aatcaacaac 360cccgacaaaa tcgacagcct gataaaccaa cgctccttcc
ttgtcagcgg tttgggcgga 420gaacataccg ccttcaacca actgcccggc
ggcaaagccg agtatcacgg caaagcattc 480agctccgacg atgccggcgg
aaaactgacc tataccatag attttgccgc caaacaggga 540cacggcaaaa
tcgaacacct gaaaacaccc gagcaaaatg tcgagcttgc cgccgccgaa
600ctcaaagcag atgaaaaatc acacgccgtc attttgggcg acacgcgcta
cggcagcgaa 660gaaaaaggca cttaccacct cgcccttttc ggcgaccgcg
ctcaagaaat cgccggctcg 720gcaaccgtga agataggaga aaaggttcac
gaaatcagca tcgccggcaa acagtag 77770258PRTNeisseria meningitidis
70Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1
5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly
Leu 20 25 30Lys Ser Leu Thr Leu Glu Asp Ser Ile Ser Gln Asn Gly Thr
Leu Thr 35 40 45Leu Ser Ala Gln Gly Ala Glu Lys Thr Phe Lys Val Gly
Asp Lys Asp 50 55 60Asn Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys
Ile Ser Arg Phe65 70 75 80Asp Phe Val Gln Lys Ile Glu Val Asp Gly
Gln Thr Ile Thr Leu Ala 85 90 95Ser Gly Glu Phe Gln Ile Tyr Lys Gln
Asn His Ser Ala Val Val Ala 100 105 110Leu Gln Ile Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile 115 120 125Asn Gln Arg Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala 130 135 140Phe Asn Gln
Leu Pro Gly Gly Lys Ala Glu Tyr His Gly Lys Ala Phe145 150 155
160Ser Ser Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
165 170 175Ala Lys Gln Gly His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln 180 185 190Asn Val Glu Leu Ala Ala Ala Glu Leu Lys Ala Asp
Glu Lys Ser His 195 200 205Ala Val Ile Leu Gly Asp Thr Arg Tyr Gly
Ser Glu Glu Lys Gly Thr 210 215 220Tyr His Leu Ala Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser225 230 235 240Ala Thr Val Lys Ile
Gly Glu Lys Val His Glu Ile Ser Ile Ala Gly 245 250 255Lys
Gln71774DNANeisseria meningitidis 71atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgaaatccc tgacattgga agactccatt 120tcccaaaacg
gaacactgac cctgtcggca caaggtgcgg aaaaaacttt caaagtcggc
180gacaaagaca acagtctcaa tacaggcaaa ttgaagaacg acaaaatcag
ccgcttcgac 240tttgtgcaaa aaatcgaagt ggacggacaa accatcacgc
tggcaagcgg cgaatttcaa 300atatacaaac agaaccactc cgccgtcgtt
gccctacaga ttgaaaaaat caacaacccc 360gacaaaatcg acagcctgat
aaaccaacgc tccttccttg tcagcggttt gggcggagaa 420cataccgcct
tcaaccaact gcccggcggc aaagccgagt atcacggcaa agcattcagc
480tccgacgatg ccggcggaaa actgacctat accatagatt ttgccgccaa
acagggacac 540ggcaaaatcg aacacctgaa aacacccgag caaaatgtcg
agcttgccgc cgccgaactc 600aaagcagatg aaaaatcaca cgccgtcatt
ttgggcgaca cgcgctacgg cagcgaagaa 660aaaggcactt accacctcgc
ccttttcggc gaccgcgctc aagaaatcgc cggctcggca 720accgtgaaga
taggagaaaa ggttcacgaa atcagcatcg ccggcaaaca gtag
77472257PRTNeisseria meningitidis 72Met Ser Ser Gly Gly Gly Gly Val
Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro
Leu Asp His Lys Asp Lys Gly Leu Lys 20 25 30Ser Leu Thr Leu Glu Asp
Ser Ile Ser Gln Asn Gly Thr Leu Thr Leu 35 40 45Ser Ala Gln Gly Ala
Glu Lys Thr Phe Lys Val Gly Asp Lys Asp Asn 50 55 60Ser Leu Asn Thr
Gly Lys Leu Lys Asn Asp Lys Ile Ser Arg Phe Asp65 70 75 80Phe Val
Gln Lys Ile Glu Val Asp Gly Gln Thr Ile Thr Leu Ala Ser 85 90 95Gly
Glu Phe Gln Ile Tyr Lys Gln Asn His Ser Ala Val Val Ala Leu 100 105
110Gln Ile Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
115 120 125Gln Arg Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe 130 135 140Asn Gln Leu Pro Gly Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser145 150 155 160Ser Asp Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala 165 170 175Lys Gln Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn 180 185 190Val Glu Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala 195 200 205Val Ile Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr 210 215 220His
Leu Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala225 230
235 240Thr Val Lys Ile Gly Glu Lys Val His Glu Ile Ser Ile Ala Gly
Lys 245 250 255Gln73765DNANeisseria meningitidis 73tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggtggaga acataccgcc
420ttcaaccaac tgcccagcgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccgcca
aacagggaca cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc
gagcttgcct ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg
cccttctcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataagggaaa aggttcacga aatcggcatt gccggcaaac agtag
76574254PRTNeisseria meningitidis 74Cys Ser Ser Gly Gly Gly Gly Val
Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro
Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln
Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala
Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu
Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile
Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln
Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105
110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser
115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn
Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe
Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile
Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu
Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu
Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr
Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu
Leu Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230
235 240Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25075768DNANeisseria meningitidis 75tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgcccttct
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc attgccggca aacagtag 76876255PRTNeisseria
meningitidis 76Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg
Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile
Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln Asp His Ser
Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn Asn Pro Asp
Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe Leu Val Ser
Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135 140Leu Pro Ser
Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp145 150 155
160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln
165 170 175Gly His Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn
Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser
His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr Gly Gly Glu Glu
Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Leu Gly Asp Arg Ala Gln
Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys Ile Arg Glu Lys
Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25577765DNANeisseria meningitidis 77atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttctcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatt gccggcaaac agtag 76578254PRTNeisseria
meningitidis 78Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Leu Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25079765DNANeisseria meningitidis 79tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76580254PRTNeisseria
meningitidis 80Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25081768DNANeisseria meningitidis 81tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76882255PRTNeisseria
meningitidis 82Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25583765DNANeisseria meningitidis 83atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76584254PRTNeisseria
meningitidis 84Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25085765DNANeisseria meningitidis 85tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76586254PRTNeisseria
meningitidis 86Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25087768DNANeisseria meningitidis 87tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76888255PRTNeisseria
meningitidis 88Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys
Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr Gly Gly Glu
Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly Asp Arg Ala
Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys Ile Arg Glu
Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25589765DNANeisseria meningitidis 89atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76590254PRTNeisseria
meningitidis 90Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25091765DNANeisseria meningitidis 91tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76592254PRTNeisseria
meningitidis 92Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25093768DNANeisseria meningitidis 93tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 76894255PRTNeisseria
meningitidis 94Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
25595765DNANeisseria meningitidis 95atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtag 76596254PRTNeisseria
meningitidis 96Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25097765DNANeisseria meningitidis 97tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccagcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc gagcttgcct
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa
aggttcacga aatcggcatc gccggcaaac agtaa 76598254PRTNeisseria
meningitidis 98Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
25099768DNANeisseria meningitidis 99tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccag cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat gtcgagcttg
cctccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcggcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg 720aagataaggg
aaaaggttca cgaaatcggc atcgccggca aacagtaa 768100255PRTNeisseria
meningitidis 100Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn
Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe
Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln 130 135
140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Thr
Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser Ala Glu Leu Lys Ala
Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr
Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215 220Ala Leu Phe Gly
Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val225 230 235 240Lys
Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245 250
255101765DNANeisseria meningitidis 101atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt
gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac tgcccagcgg
caaagccgag tatcacggca aagcattcag ctccgacgat 480gctggcggaa
aactgaccta taccatagat ttcgccgcca aacagggaca cggcaaaatc
540gaacacttga aaacacccga gcaaaatgtc gagcttgcct ccgccgaact
caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac acgcgctacg
gcggcgaaga aaaaggcact 660taccacctcg cccttttcgg cgaccgcgcc
caagaaatcg ccggctcggc aaccgtgaag 720ataagggaaa aggttcacga
aatcggcatc gccggcaaac agtaa 765102254PRTNeisseria meningitidis
102Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1
5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu
Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp His Ser Ala
Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys
Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly
Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Ser Gly
Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155
160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln Gly
165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val
Glu Leu 180 185 190Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His
Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys
Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu
Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile Arg Glu Lys Val
His Glu Ile Gly Ile Ala Gly Lys Gln 245 250103765DNANeisseria
meningitidis 103tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca aatatacaaa
300caggaccact ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc
cgacaaaatc 360gacagcctga taaaccaacg ctccttcctt gtcagcggtt
tgggtggaga acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag
tatcacggca aagcattcag ctccgacgat 480gctggcggaa aactgaccta
taccatagat ttcgccgcca aacagggaca cggcaaaatc 540gaacacttga
aaacacccga gcaaaatgtc gagcttgcct ccgccgaact caaagcagat
600gaaaaatcac acgccgtcat tttgggcgac acgcgctacg gcggcgaaga
aaaaggcact 660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg
ccggctcggc aaccgtgaag 720ataagggaaa aggttcacga aatcggcatc
gccggcaaac agtag 765104254PRTNeisseria meningitidis 104Cys Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser
Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40
45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn
50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile
Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser
Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala
Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser
Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly
Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu
Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly
Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His
Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185
190Ala Ser Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu
195 200 205Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His
Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser
Ala Thr Val Lys225 230 235 240Ile Arg Glu Lys Val His Glu Ile Gly
Ile Ala Gly Lys Gln 245 250105768DNANeisseria meningitidis
105tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct
tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt ctttgacgct
ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg
cggaaaaaac ttatggaaac 180ggcgacagcc ttaatacggg caaattgaag
aacgacaagg tcagccgttt cgactttatc 240cgtcaaatcg aagtggacgg
gcagctcatt accttggaga gcggagagtt ccaaatatac 300aaacaggacc
actccgccgt cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa
360atcgacagcc tgataaacca acgctccttc cttgtcagcg gtttgggtgg
agaacatacc 420gccttcaacc aactgcccag cggcaaagcc gagtatcacg
gcaaagcatt cagctccgac 480gatgctggcg gaaaactgac ctataccata
gatttcgccg ccaaacaggg acacggcaaa 540atcgaacact tgaaaacacc
cgagcaaaat gtcgagcttg cctccgccga actcaaagca 600gatgaaaaat
cacacgccgt cattttgggc gacacgcgct acggcggcga agaaaaaggc
660acttaccacc tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc
ggcaaccgtg 720aagataaggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768106255PRTNeisseria meningitidis 106Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ser
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255107765DNANeisseria meningitidis
107atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctta atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggtggaga
acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacttga aaacacccga
gcaaaatgtc gagcttgcct ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcggcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataagggaaa aggttcacga aatcggcatc gccggcaaac agtag
765108254PRTNeisseria meningitidis 108Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ser Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Gly Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Arg Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250109765DNANeisseria meningitidis 109tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg agaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggcggaga acataccgcc
420ttcaaccaac tgcctgacgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccgcca
aacagggaca cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765110254PRTNeisseria meningitidis 110Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250111768DNANeisseria meningitidis 111tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggagaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768112255PRTNeisseria meningitidis 112Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255113765DNANeisseria meningitidis
113atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
agaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765114254PRTNeisseria meningitidis 114Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50
55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile
Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser
Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala
Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser
Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly
Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu
Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly
Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His
Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185
190Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu
195 200 205Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His
Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser
Ala Thr Val Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly
Ile Ala Gly Lys Gln 245 250115765DNANeisseria meningitidis
115tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765116254PRTNeisseria meningitidis 116Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250117768DNANeisseria meningitidis 117tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768118255PRTNeisseria meningitidis 118Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255119765DNANeisseria meningitidis
119atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765120254PRTNeisseria meningitidis 120Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250121765DNANeisseria meningitidis 121tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggcggaga acataccgcc
420ttcaaccaac tgcctgacgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccgcca
aacagggaca cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765122254PRTNeisseria meningitidis 122Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250123768DNANeisseria meningitidis 123tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768124255PRTNeisseria meningitidis 124Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255125765DNANeisseria meningitidis
125atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765126254PRTNeisseria meningitidis 126Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180
185 190Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile
Leu 195 200 205Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr
His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly
Ser Ala Thr Val Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile
Gly Ile Ala Gly Lys Gln 245 250127765DNANeisseria meningitidis
127tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765128254PRTNeisseria meningitidis 128Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250129768DNANeisseria meningitidis 129tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768130255PRTNeisseria meningitidis 130Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255131765DNANeisseria meningitidis
131atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765132254PRTNeisseria meningitidis 132Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250133765DNANeisseria meningitidis 133tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggcggaga acataccgcc
420ttcaaccaac tgcctgacgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccgcca
aacagggaca cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtaa
765134254PRTNeisseria meningitidis 134Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250135768DNANeisseria meningitidis 135tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtaa
768136255PRTNeisseria meningitidis 136Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255137765DNANeisseria meningitidis
137atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtaa
765138254PRTNeisseria meningitidis 138Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250139765DNANeisseria meningitidis 139tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctta atacgggcaa attgaagaac gacaaggtca
gccgtttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggtggaga
acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccacca aacagggaca cggcaaaatc 540gaacacttga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765140254PRTNeisseria meningitidis 140Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Thr Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250141768DNANeisseria meningitidis 141tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc ttaatacggg caaattgaag aacgacaagg
tcagccgttt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggtgg agaacatacc
420gccttcaacc aactgcccag cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgcca
ccaaacaggg acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768142255PRTNeisseria meningitidis 142Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Thr Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255143765DNANeisseria meningitidis
143atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctta atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggtggaga
acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccacca aacagggaca cggcaaaatc 540gaacacttga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765144254PRTNeisseria meningitidis 144Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Thr Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250145765DNANeisseria meningitidis 145tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctta atacgggcaa attgaagaac gacaaggtca
gccgtttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggtggaga acataccgcc
420ttcaaccaac tgcccagcgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccacca
aacagggaca cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765146254PRTNeisseria meningitidis 146Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Thr Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250147768DNANeisseria meningitidis 147tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc ttaatacggg caaattgaag aacgacaagg
tcagccgttt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggtgg agaacatacc
420gccttcaacc aactgcccag cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgcca
ccaaacaggg acacggcaaa 540atcgaacact tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768148255PRTNeisseria meningitidis 148Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Ser Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Thr Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255149765DNANeisseria meningitidis
149atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctta atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggtggaga
acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccacca aacagggaca cggcaaaatc 540gaacacttga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765150254PRTNeisseria meningitidis 150Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Thr Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250151765DNANeisseria meningitidis 151tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctta atacgggcaa attgaagaac gacaaggtca
gccgtttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggtggaga acataccgcc
420ttcaaccaac tgcccagcgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccacca
aacagggaca cggcaaaatc 540gaacacttga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765152254PRTNeisseria meningitidis 152Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly
Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg
Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile
Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp His Ser
Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp
Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser
Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Ser
Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155
160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Thr Lys Gln Gly
165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val
Glu Leu 180 185 190Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His
Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys
Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu
Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile Gly Glu Lys Val
His Glu Ile Gly Ile Ala Gly Lys Gln 245 250153768DNANeisseria
meningitidis 153tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg
gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt
ctttgacgct ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg
gcacaaggtg cggaaaaaac ttatggaaac 180ggcgacagcc ttaatacggg
caaattgaag aacgacaagg tcagccgttt cgactttatc 240cgtcaaatcg
aagtggacgg gcagctcatt accttggaga gcggagagtt ccaaatatac
300aaacaggacc actccgccgt cgttgcccta cagattgaaa aaatcaacaa
ccccgacaaa 360atcgacagcc tgataaacca acgctccttc cttgtcagcg
gtttgggtgg agaacatacc 420gccttcaacc aactgcccag cggcaaagcc
gagtatcacg gcaaagcatt cagctccgac 480gatgctggcg gaaaactgac
ctataccata gatttcgcca ccaaacaggg acacggcaaa 540atcgaacact
tgaaaacacc cgagcaaaat gtcgagcttg ccgccgccga actcaaagca
600gatgaaaaat cacacgccgt cattttgggc gacacgcgct acggcagcga
agaaaaaggc 660acttaccacc tcgccctttt cggcgaccgc gcccaagaaa
tcgccggctc ggcaaccgtg 720aagatagggg aaaaggttca cgaaatcggc
atcgccggca aacagtag 768154255PRTNeisseria meningitidis 154Cys Gly
Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu
Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25
30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys
35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser
Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp
Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu
Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val
Val Ala Leu Gln Ile 100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile
Asp Ser Leu Ile Asn Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu
Gly Gly Glu His Thr Ala Phe Asn Gln 130 135 140Leu Pro Ser Gly Lys
Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Thr Lys Gln 165 170
175Gly His Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu
180 185 190Leu Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala
Val Ile 195 200 205Leu Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly
Thr Tyr His Leu 210 215 220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile
Ala Gly Ser Ala Thr Val225 230 235 240Lys Ile Gly Glu Lys Val His
Glu Ile Gly Ile Ala Gly Lys Gln 245 250 255155765DNANeisseria
meningitidis 155atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca aatatacaaa
300caggaccact ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc
cgacaaaatc 360gacagcctga taaaccaacg ctccttcctt gtcagcggtt
tgggtggaga acataccgcc 420ttcaaccaac tgcccagcgg caaagccgag
tatcacggca aagcattcag ctccgacgat 480gctggcggaa aactgaccta
taccatagat ttcgccacca aacagggaca cggcaaaatc 540gaacacttga
aaacacccga gcaaaatgtc gagcttgccg ccgccgaact caaagcagat
600gaaaaatcac acgccgtcat tttgggcgac acgcgctacg gcagcgaaga
aaaaggcact 660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg
ccggctcggc aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc
gccggcaaac agtag 765156254PRTNeisseria meningitidis 156Met Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser
Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40
45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn
50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile
Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser
Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala
Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser
Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly
Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Ser Gly Lys Ala Glu
Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly
Lys Leu Thr Tyr Thr Ile Asp Phe Ala Thr Lys Gln Gly 165 170 175His
Gly Lys Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185
190Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu
195 200 205Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His
Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser
Ala Thr Val Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly
Ile Ala Gly Lys Gln 245 250157765DNANeisseria meningitidis
157tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgactataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctatag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggtggaga
acataccgcc 420ttcaaccaac tgcccggcgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgct caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765158253PRTNeisseria meningitidis 158Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp Tyr Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Ile Glu Lys
100 105 110Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg
Ser Phe 115 120 125Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe
Asn Gln Leu Pro 130 135 140Gly Gly Lys Ala Glu Tyr His Gly Lys Ala
Phe Ser Ser Asp Asp Ala145 150 155 160Gly Gly Lys Leu Thr Tyr Thr
Ile Asp Phe Ala Ala Lys Gln Gly His 165 170 175Gly Lys Ile Glu His
Leu Lys Thr Pro Glu Gln Asn Val Glu Leu Ala 180 185 190Ala Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu Gly 195 200 205Asp
Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala Leu 210 215
220Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys
Ile225 230 235 240Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys
Gln 245 250159768DNANeisseria meningitidis 159tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacta
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaaatatac 300aaacaggacc actccgccgt cgttgcccta
tagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc tgataaacca
acgctccttc cttgtcagcg gtttgggtgg agaacatacc 420gccttcaacc
aactgcccgg cggcaaagcc gagtatcacg gcaaagcatt cagctccgac
480gatgctggcg gaaaactgac ctataccata gatttcgccg ccaaacaggg
acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat gtcgagcttg
ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt cattttgggc
gacacgcgct acggcagcga agaaaaaggc 660acttaccacc tcgccctttt
cggcgaccgc gctcaagaaa tcgccggctc ggcaaccgtg 720aagatagggg
aaaaggttca cgaaatcggc atcgccggca aacagtag 768160254PRTNeisseria
meningitidis 160Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp Tyr Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Ile Tyr Lys Gln
Asp His Ser Ala Val Val Ala Leu Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Gly Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala Glu Leu Lys Ala Asp
Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly Asp Thr Arg Tyr Gly
Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215 220Leu Phe Gly Asp
Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys225 230 235 240Ile
Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
250161765DNANeisseria meningitidis 161atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgactataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctatag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggtggaga acataccgcc 420ttcaaccaac
tgcccggcgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc gagcttgccg
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgct caagaaatcg ccggctcggc aaccgtgaag 720ataggggaaa
aggttcacga aatcggcatc gccggcaaac agtag 765162253PRTNeisseria
meningitidis 162Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp Tyr Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Ile Glu Lys 100 105 110Ile Asn Asn Pro
Asp Lys Ile Asp Ser Leu Ile Asn Gln Arg Ser Phe 115 120 125Leu Val
Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu Pro 130 135
140Gly Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp
Ala145 150 155 160Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala
Lys Gln Gly His 165 170 175Gly Lys Ile Glu His Leu Lys Thr Pro Glu
Gln Asn Val Glu Leu Ala 180 185 190Ala Ala Glu Leu Lys Ala Asp Glu
Lys Ser His Ala Val Ile Leu Gly 195 200 205Asp Thr Arg Tyr Gly Ser
Glu Glu Lys Gly Thr Tyr His Leu Ala Leu 210 215 220Phe Gly Asp Arg
Ala Gln Glu Ile Ala Gly Ser Ala Thr Val Lys Ile225 230 235 240Gly
Glu Lys Val His Glu Ile Gly Ile Ala Gly Lys Gln 245
250163765DNANeisseria meningitidis 163tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca aatatacaaa 300caggaccact ccgccgtcgt tgccctacag
attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga taaaccgacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 420ttcaaccaac
tgcctgacgg caaagccgag tatcacggca aagcattcag ctccgacgat
480gctggcggaa aactgaccta taccatagat ttcgccgcca aacagggaca
cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc gagcttgccg
ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat tttgggcgac
acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg cccttttcgg
cgaccgcgcc caagaaatcg ccggctcggc aaccgtgaag 720ataggggaaa
aggttcacga aatcggcatc gccggcaaac agtag 765164254PRTNeisseria
meningitidis 164Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Asp
His Ser Ala Val Val Ala Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn
Pro Asp Lys Ile Asp Ser Leu Ile Asn Arg Arg Ser 115 120 125Phe Leu
Val Ser Gly Leu Gly Gly Glu His Thr Ala Phe Asn Gln Leu 130 135
140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp
Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala
Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu His Leu Lys Thr Pro
Glu Gln Asn Val Glu Leu 180
185 190Ala Ala Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile
Leu 195 200 205Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr
His Leu Ala 210 215 220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly
Ser Ala Thr Val Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile
Gly Ile Ala Gly Lys Gln 245 250165768DNANeisseria meningitidis
165tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct
tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt ctttgacgct
ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg
cggaaaaaac ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag
aacgacaagg tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg
gcagctcatt accttggaga gcggagagtt ccaaatatac 300aaacaggacc
actccgccgt cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa
360atcgacagcc tgataaaccg acgctccttc cttgtcagcg gtttgggcgg
agaacatacc 420gccttcaacc aactgcctga cggcaaagcc gagtatcacg
gcaaagcatt cagctccgac 480gatgctggcg gaaaactgac ctataccata
gatttcgccg ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc
cgagcaaaat gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat
cacacgccgt cattttgggc gacacgcgct acggcagcga agaaaaaggc
660acttaccacc tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc
ggcaaccgtg 720aagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768166255PRTNeisseria meningitidis 166Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Arg Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Lys Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255167765DNANeisseria meningitidis
167atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccgacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtgaag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765168254PRTNeisseria meningitidis 168Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Arg
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Lys225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250169765DNANeisseria meningitidis 169tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca aatatacaaa 300caggaccact ccgccgtcgt
tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc 360gacagcctga
taaaccaacg ctccttcctt gtcagcggtt tgggcggaga acataccgcc
420ttcaaccaac tgcctgacgg caaagccgag tatcacggca aagcattcag
ctccgacgat 480gctggcggaa aactgaccta taccatagat ttcgccgcca
aacagggaca cggcaaaatc 540gaacacctga aaacacccga gcaaaatgtc
gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac acgccgtcat
tttgggcgac acgcgctacg gcagcgaaga aaaaggcact 660taccacctcg
cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc aaccgtggag
720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765170254PRTNeisseria meningitidis 170Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Glu225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250171768DNANeisseria meningitidis 171tgcggatcca
gcggaggcgg cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa agtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt
accttggaga gcggagagtt ccaaatatac 300aaacaggacc actccgccgt
cgttgcccta cagattgaaa aaatcaacaa ccccgacaaa 360atcgacagcc
tgataaacca acgctccttc cttgtcagcg gtttgggcgg agaacatacc
420gccttcaacc aactgcctga cggcaaagcc gagtatcacg gcaaagcatt
cagctccgac 480gatgctggcg gaaaactgac ctataccata gatttcgccg
ccaaacaggg acacggcaaa 540atcgaacacc tgaaaacacc cgagcaaaat
gtcgagcttg ccgccgccga actcaaagca 600gatgaaaaat cacacgccgt
cattttgggc gacacgcgct acggcagcga agaaaaaggc 660acttaccacc
tcgccctttt cggcgaccgc gcccaagaaa tcgccggctc ggcaaccgtg
720gagatagggg aaaaggttca cgaaatcggc atcgccggca aacagtag
768172255PRTNeisseria meningitidis 172Cys Gly Ser Ser Gly Gly Gly
Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu
Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg
Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90
95Phe Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile
100 105 110Glu Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn
Gln Arg 115 120 125Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr
Ala Phe Asn Gln 130 135 140Leu Pro Asp Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe Ser Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu 180 185 190Leu Ala Ala
Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile 195 200 205Leu
Gly Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu 210 215
220Ala Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr
Val225 230 235 240Glu Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala
Gly Lys Gln 245 250 255173765DNANeisseria meningitidis
173atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggc 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgcttcga ctttatccgt 240caaatcgaag tggacgggca
gctcattacc ttggagagcg gagagttcca aatatacaaa 300caggaccact
ccgccgtcgt tgccctacag attgaaaaaa tcaacaaccc cgacaaaatc
360gacagcctga taaaccaacg ctccttcctt gtcagcggtt tgggcggaga
acataccgcc 420ttcaaccaac tgcctgacgg caaagccgag tatcacggca
aagcattcag ctccgacgat 480gctggcggaa aactgaccta taccatagat
ttcgccgcca aacagggaca cggcaaaatc 540gaacacctga aaacacccga
gcaaaatgtc gagcttgccg ccgccgaact caaagcagat 600gaaaaatcac
acgccgtcat tttgggcgac acgcgctacg gcagcgaaga aaaaggcact
660taccacctcg cccttttcgg cgaccgcgcc caagaaatcg ccggctcggc
aaccgtggag 720ataggggaaa aggttcacga aatcggcatc gccggcaaac agtag
765174254PRTNeisseria meningitidis 174Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Ile Tyr Lys Gln Asp His Ser Ala Val Val Ala Leu Gln Ile Glu
100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser Leu Ile Asn Gln
Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly Glu His Thr Ala
Phe Asn Gln Leu 130 135 140Pro Asp Gly Lys Ala Glu Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp145 150 155 160Ala Gly Gly Lys Leu Thr Tyr
Thr Ile Asp Phe Ala Ala Lys Gln Gly 165 170 175His Gly Lys Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185 190Ala Ala Ala
Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu 195 200 205Gly
Asp Thr Arg Tyr Gly Ser Glu Glu Lys Gly Thr Tyr His Leu Ala 210 215
220Leu Phe Gly Asp Arg Ala Gln Glu Ile Ala Gly Ser Ala Thr Val
Glu225 230 235 240Ile Gly Glu Lys Val His Glu Ile Gly Ile Ala Gly
Lys Gln 245 250175768DNANeisseria meningitidis 175tgcagcagcg
gaggcggcgg tgtcgccgcc gacatcggcg cggtgcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggc 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgcttcga ctttatccgt 240caaatcgaag tggacgggca gctcattacc
ttggagagcg gagagttcca agtgtacaaa 300caaagccatt ccgccttaac
cgcccttcag accgagcaag tacaagattc ggagcattca 360gggaagatgg
ttgcgaaacg ccagttcaga atcggcgata tagcgggtga acatacatct
420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg ggacggcatt
cggttcagac 480gatgccagtg gaaaactgac ctacaccata gatttcgccg
ccaagcaggg acacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat
gttgacctgg ccgcctccga tatcaagccg 600gataaaaaac gccatgccgt
catcagcggt tccgtccttt acaaccaagc cgagaaaggc 660agttactctc
taggcatctt tggcgggcaa gcccaggaag ttgccggcag cgcagaagtg
720gaaaccgcaa acggcatacg ccatatcggt cttgccgcca agcagtaa
768176255PRTNeisseria meningitidis 176Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Val Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Leu Gln Thr Glu
100 105 110Gln Val Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Ser Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ser Asp Ile Lys Pro Asp Lys Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Glu Thr Ala Asn Gly Ile Arg His Ile Gly Leu Ala
Ala Lys Gln 245 250 255177771DNANeisseria meningitidis
177tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg gcgcggtgct
tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt ctttgacgct
ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg
cggaaaaaac ttatggaaac 180ggcgacagcc tcaatacggg caaattgaag
aacgacaagg tcagccgctt cgactttatc 240cgtcaaatcg aagtggacgg
gcagctcatt accttggaga gcggagagtt ccaagtgtac 300aaacaaagcc
attccgcctt aaccgccctt
cagaccgagc aagtacaaga ttcggagcat 360tcagggaaga tggttgcgaa
acgccagttc agaatcggcg atatagcggg tgaacataca 420tcttttgaca
agcttcccga aggcggcagg gcgacatatc gcgggacggc attcggttca
480gacgatgcca gtggaaaact gacctacacc atagatttcg ccgccaagca
gggacacggc 540aaaatcgaac atttgaaatc gccagaactc aatgttgacc
tggccgcctc cgatatcaag 600ccggataaaa aacgccatgc cgtcatcagc
ggttccgtcc tttacaacca agccgagaaa 660ggcagttact ctctaggcat
ctttggcggg caagcccagg aagttgccgg cagcgcagaa 720gtggaaaccg
caaacggcat acgccatatc ggtcttgccg ccaagcagta a 771178256PRTNeisseria
meningitidis 178Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Val1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Val Gln
Asp Ser Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Ser Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly His Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Asp Leu Ala Ala Ser Asp Ile Lys
Pro Asp Lys Lys Arg His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Glu Thr Ala Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255179768DNANeisseria meningitidis 179atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggtgcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag tacaagattc ggagcattca 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgata tagcgggtga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcatt cggttcagac
480gatgccagtg gaaaactgac ctacaccata gatttcgccg ccaagcaggg
acacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat gttgacctgg
ccgcctccga tatcaagccg 600gataaaaaac gccatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactctc taggcatctt
tggcgggcaa gcccaggaag ttgccggcag cgcagaagtg 720gaaaccgcaa
acggcatacg ccatatcggt cttgccgcca agcagtaa 768180255PRTNeisseria
meningitidis 180Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Val Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Val Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Ser Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ser Asp Ile Lys Pro
Asp Lys Lys Arg His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Glu
Thr Ala Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255181747DNANeisseria meningitidis 181tgcagcagcg gagggggtgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggt
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgc 240caaatcgaag tggacgggca gctcattacc ttggagagtg
gagagttcca agtatacaaa 300caaagccatt ccgccttaac cgcctttcag
accgagcaaa tacaagattc ggagcattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctacaccata gatttcgccg ccaagcaggg
aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggcatacg ccatatc 747182249PRTNeisseria meningitidis 182Cys Ser
Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25
30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu
35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu
Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe
Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu
Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly
Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala
Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg
Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170
175Gly Asn Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp
180 185 190Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala
Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly
Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val
Ala Gly Ser Ala Glu Val225 230 235 240Lys Thr Val Asn Gly Ile Arg
His Ile 245183750DNANeisseria meningitidis 183tgcggatcca gcggaggggg
tggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa ggtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggtgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgttt
cgactttatc 240cgccaaatcg aagtggacgg gcagctcatt accttggaga
gtggagagtt ccaagtatac 300aaacaaagcc attccgcctt aaccgccttt
cagaccgagc aaatacaaga ttcggagcat 360tccgggaaga tggttgcgaa
acgccagttc agaatcggcg acatagcggg cgaacataca 420tcttttgaca
agcttcccga aggcggcagg gcgacatatc gcgggacggc gttcggttca
480gacgatgccg gcggaaaact gacctacacc atagatttcg ccgccaagca
gggaaacggc 540aaaatcgaac atttgaaatc gccagaactc aatgtcgacc
tggccgccgc cgatatcaag 600ccggatggaa aacgccatgc cgtcatcagc
ggttccgtcc tttacaacca agccgagaaa 660ggcagttact ccctcggtat
ctttggcgga aaagcccagg aagttgccgg cagcgcggaa 720gtgaaaaccg
taaacggcat acgccatatc 750184250PRTNeisseria meningitidis 184Cys Gly
Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu
Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu 20 25
30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys
35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser
Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp
Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu
Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln Ser His Ser Ala Leu
Thr Ala Phe Gln Thr 100 105 110Glu Gln Ile Gln Asp Ser Glu His Ser
Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe Arg Ile Gly Asp Ile
Ala Gly Glu His Thr Ser Phe Asp Lys 130 135 140Leu Pro Glu Gly Gly
Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser145 150 155 160Asp Asp
Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys 165 170
175Gln Gly Asn Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val
180 185 190Asp Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg His
Ala Val 195 200 205Ile Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys
Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe Gly Gly Lys Ala Gln Glu
Val Ala Gly Ser Ala Glu225 230 235 240Val Lys Thr Val Asn Gly Ile
Arg His Ile 245 250185747DNANeisseria meningitidis 185atgagcagcg
gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggt 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgtttcga ctttatccgc 240caaatcgaag tggacgggca gctcattacc
ttggagagtg gagagttcca agtatacaaa 300caaagccatt ccgccttaac
cgcctttcag accgagcaaa tacaagattc ggagcattcc 360gggaagatgg
ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga acatacatct
420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt
cggttcagac 480gatgccggcg gaaaactgac ctacaccata gatttcgccg
ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat
gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt
catcagcggt tccgtccttt acaaccaagc cgagaaaggc 660agttactccc
tcggtatctt tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg
720aaaaccgtaa acggcatacg ccatatc 747186249PRTNeisseria meningitidis
186Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1
5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu
Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala
Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp Ser Glu His
Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg Ile Gly Asp
Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Glu Gly
Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155
160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln
165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn
Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg
His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu
Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Lys Ala Gln
Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys Thr Val Asn Gly
Ile Arg His Ile 245187747DNANeisseria meningitidis 187tgcagcagcg
gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc
tcgaccataa agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc
120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg aaaaaactta
tggaaacggt 180gacagcctca atacgggcaa attgaagaac gacaaggtca
gccgtttcga ctttatccgc 240caaatcgaag tggacgggca gctcattacc
ttggagagtg gagagttcca agtatacaaa 300caaagccatt ccgccttaac
cgcctttcag accgagcaaa tacaagattc ggagcattcc 360gggaagatgg
ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga acatacatct
420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt
cggttcagac 480gatgccggcg gaaaactgac ctacaccata gatttcgccg
ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat
gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt
catcagcggt tccgtccttt acaaccaagc cgagaaaggc 660agttactccc
tcggtatctt tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg
720aaaaccgtaa acggcatacg ccatatc 747188249PRTNeisseria meningitidis
188Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1
5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu
Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala
Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp Ser Glu His
Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg Ile Gly Asp
Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Glu Gly
Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155
160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln
165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn
Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg
His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu
Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Lys Ala Gln
Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys Thr Val Asn Gly
Ile Arg His Ile 245189750DNANeisseria meningitidis 189tgcggatcca
gcggaggggg tggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac
cgctcgacca taaagacaaa ggtttgcagt ctttgacgct ggatcagtcc
120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg cggaaaaaac
ttatggaaac 180ggtgacagcc tcaatacggg caaattgaag aacgacaagg
tcagccgttt cgactttatc 240cgccaaatcg aagtggacgg gcagctcatt
accttggaga gtggagagtt ccaagtatac 300aaacaaagcc attccgcctt
aaccgccttt cagaccgagc aaatacaaga ttcggagcat 360tccgggaaga
tggttgcgaa acgccagttc agaatcggcg acatagcggg cgaacataca
420tcttttgaca agcttcccga aggcggcagg gcgacatatc gcgggacggc
gttcggttca 480gacgatgccg gcggaaaact gacctacacc atagatttcg
ccgccaagca gggaaacggc 540aaaatcgaac atttgaaatc gccagaactc
aatgtcgacc tggccgccgc cgatatcaag 600ccggatggaa aacgccatgc
cgtcatcagc ggttccgtcc tttacaacca agccgagaaa 660ggcagttact
ccctcggtat ctttggcgga aaagcccagg aagttgccgg cagcgcggaa
720gtgaaaaccg taaacggcat acgccatatc 750190250PRTNeisseria
meningitidis 190Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Gly Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp
Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Phe Gln Thr 100 105 110Glu Gln Ile Gln
Asp Ser Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly Asn Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Asp Leu Ala Ala Ala Asp Ile Lys
Pro Asp Gly Lys Arg His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Lys Thr Val Asn Gly Ile Arg His Ile 245 250191747DNANeisseria
meningitidis 191atgagcagcg gagggggtgg tgtcgccgcc gacatcggtg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggt 180gacagcctca atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgc 240caaatcgaag
tggacgggca gctcattacc ttggagagtg gagagttcca agtatacaaa
300caaagccatt ccgccttaac cgcctttcag accgagcaaa tacaagattc
ggagcattcc 360gggaagatgg ttgcgaaacg ccagttcaga atcggcgaca
tagcgggcga acatacatct 420tttgacaagc ttcccgaagg cggcagggcg
acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac
ctacaccata gatttcgccg ccaagcaggg aaacggcaaa 540atcgaacatt
tgaaatcgcc agaactcaat gtcgacctgg ccgccgccga tatcaagccg
600gatggaaaac gccatgccgt catcagcggt tccgtccttt acaaccaagc
cgagaaaggc 660agttactccc tcggtatctt tggcggaaaa gcccaggaag
ttgccggcag cgcggaagtg 720aaaaccgtaa acggcatacg ccatatc
747192249PRTNeisseria meningitidis 192Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe Gln Thr Glu
100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Lys Thr Val Asn Gly Ile Arg His Ile
245193768DNANeisseria meningitidis 193tgcagcagcg gagggggtgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggt
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgc 240caaatcgaag tggacgggca gctcattacc ttggagagtg
gagagttcca agtatacaaa 300caaagccatt ccgccttaac cgcctttcag
accgagcaaa tacaagattc ggagcattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctacaccata gatttcgccg ccaagcaggg
aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggcatacg ccatatcggc cttgccgcca agcaataa 768194255PRTNeisseria
meningitidis 194Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro
Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys
Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255195771DNANeisseria meningitidis 195tgcggatcca gcggaggggg
tggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa ggtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggtgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgttt
cgactttatc 240cgccaaatcg aagtggacgg gcagctcatt accttggaga
gtggagagtt ccaagtatac 300aaacaaagcc attccgcctt aaccgccttt
cagaccgagc aaatacaaga ttcggagcat 360tccgggaaga tggttgcgaa
acgccagttc agaatcggcg acatagcggg cgaacataca 420tcttttgaca
agcttcccga aggcggcagg gcgacatatc gcgggacggc gttcggttca
480gacgatgccg gcggaaaact gacctacacc atagatttcg ccgccaagca
gggaaacggc 540aaaatcgaac atttgaaatc gccagaactc aatgtcgacc
tggccgccgc cgatatcaag 600ccggatggaa aacgccatgc cgtcatcagc
ggttccgtcc tttacaacca agccgagaaa 660ggcagttact ccctcggtat
ctttggcgga aaagcccagg aagttgccgg cagcgcggaa 720gtgaaaaccg
taaacggcat acgccatatc ggccttgccg ccaagcaata a 771196256PRTNeisseria
meningitidis 196Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Gly Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Phe Gln Thr 100 105 110Glu Gln Ile Gln
Asp Ser Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly Asn Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Asp Leu Ala Ala Ala Asp Ile Lys
Pro Asp Gly Lys Arg His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255197768DNANeisseria meningitidis 197atgagcagcg gagggggtgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggt
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgc 240caaatcgaag tggacgggca gctcattacc ttggagagtg
gagagttcca agtatacaaa 300caaagccatt ccgccttaac cgcctttcag
accgagcaaa tacaagattc ggagcattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctacaccata gatttcgccg ccaagcaggg
aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggcatacg ccatatcggc cttgccgcca agcaataa 768198255PRTNeisseria
meningitidis 198Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro
Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys
Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255199768DNANeisseria meningitidis 199tgcagcagcg gagggggtgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggt
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgc 240caaatcgaag tggacgggca gctcattacc ttggagagtg
gagagttcca agtatacaaa 300caaagccatt ccgccttaac cgcctttcag
accgagcaaa tacaagattc ggagcattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctacaccata gatttcgccg ccaagcaggg
aaacggcaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatggaaaac gccatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggcatacg ccatatcggc cttgccgcca agcaataa 768200255PRTNeisseria
meningitidis 200Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro
Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys
Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255201771DNANeisseria meningitidis 201tgcggatcca gcggaggggg
tggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa ggtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggtgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgttt
cgactttatc 240cgccaaatcg aagtggacgg gcagctcatt accttggaga
gtggagagtt ccaagtatac 300aaacaaagcc attccgcctt aaccgccttt
cagaccgagc aaatacaaga ttcggagcat 360tccgggaaga tggttgcgaa
acgccagttc agaatcggcg acatagcggg cgaacataca 420tcttttgaca
agcttcccga aggcggcagg gcgacatatc gcgggacggc gttcggttca
480gacgatgccg gcggaaaact gacctacacc atagatttcg ccgccaagca
gggaaacggc 540aaaatcgaac atttgaaatc gccagaactc aatgtcgacc
tggccgccgc cgatatcaag 600ccggatggaa aacgccatgc cgtcatcagc
ggttccgtcc tttacaacca agccgagaaa 660ggcagttact ccctcggtat
ctttggcgga aaagcccagg aagttgccgg cagcgcggaa 720gtgaaaaccg
taaacggcat acgccatatc ggccttgccg ccaagcaata a 771202256PRTNeisseria
meningitidis 202Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Gly Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Phe Gln Thr 100 105 110Glu Gln Ile Gln
Asp Ser Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly Asn Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Asp
Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val 195 200
205Ile Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser
210 215 220Leu Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser
Ala Glu225 230 235 240Val Lys Thr Val Asn Gly Ile Arg His Ile Gly
Leu Ala Ala Lys Gln 245 250 255203768DNANeisseria meningitidis
203atgagcagcg gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggt 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgc 240caaatcgaag tggacgggca
gctcattacc ttggagagtg gagagttcca agtatacaaa 300caaagccatt
ccgccttaac cgcctttcag accgagcaaa tacaagattc ggagcattcc
360gggaagatgg ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga
acatacatct 420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg
ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac ctacaccata
gatttcgccg ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc
agaactcaat gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac
gccatgccgt catcagcggt tccgtccttt acaaccaagc cgagaaaggc
660agttactccc tcggtatctt tggcggaaaa gcccaggaag ttgccggcag
cgcggaagtg 720aaaaccgtaa acggcatacg ccatatcggc cttgccgcca agcaataa
768204255PRTNeisseria meningitidis 204Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe Gln Thr Glu
100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala
Ala Lys Gln 245 250 255205768DNANeisseria meningitidis
205tgcagcagcg gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggt 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgc 240caaatcgaag tggacgggca
gctcattacc ttggagagtg gagagttcca agtatacaaa 300caaagccatt
ccgccttaac cgcctttcag accgagcaaa tacaagattc ggagcattcc
360gggaagatgg ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga
acatacatct 420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg
ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac ctacaccata
gatttcgccg ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc
agaactcaat gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac
gccatgccgt catcagcggt tccgtccttt acaaccaagc cgagaaaggc
660agttactccc tcggtatctt tggcggaaaa gcccaggaag ttgccggcag
cgcggaagtg 720aaaaccgtaa acggcatacg ccatatcggc cttgccgcca agcaataa
768206255PRTNeisseria meningitidis 206Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe Gln Thr Glu
100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala
Ala Lys Gln 245 250 255207771DNANeisseria meningitidis
207tgcggatcca gcggaggggg tggtgtcgcc gccgacatcg gtgcggggct
tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa ggtttgcagt ctttgacgct
ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg
cggaaaaaac ttatggaaac 180ggtgacagcc tcaatacggg caaattgaag
aacgacaagg tcagccgttt cgactttatc 240cgccaaatcg aagtggacgg
gcagctcatt accttggaga gtggagagtt ccaagtatac 300aaacaaagcc
attccgcctt aaccgccttt cagaccgagc aaatacaaga ttcggagcat
360tccgggaaga tggttgcgaa acgccagttc agaatcggcg acatagcggg
cgaacataca 420tcttttgaca agcttcccga aggcggcagg gcgacatatc
gcgggacggc gttcggttca 480gacgatgccg gcggaaaact gacctacacc
atagatttcg ccgccaagca gggaaacggc 540aaaatcgaac atttgaaatc
gccagaactc aatgtcgacc tggccgccgc cgatatcaag 600ccggatggaa
aacgccatgc cgtcatcagc ggttccgtcc tttacaacca agccgagaaa
660ggcagttact ccctcggtat ctttggcgga aaagcccagg aagttgccgg
cagcgcggaa 720gtgaaaaccg taaacggcat acgccatatc ggccttgccg
ccaagcaata a 771208256PRTNeisseria meningitidis 208Cys Gly Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu 20 25 30Gln Ser
Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu
Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55
60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65
70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly
Glu 85 90 95Phe Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe
Gln Thr 100 105 110Glu Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met
Val Ala Lys Arg 115 120 125Gln Phe Arg Ile Gly Asp Ile Ala Gly Glu
His Thr Ser Phe Asp Lys 130 135 140Leu Pro Glu Gly Gly Arg Ala Thr
Tyr Arg Gly Thr Ala Phe Gly Ser145 150 155 160Asp Asp Ala Gly Gly
Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys 165 170 175Gln Gly Asn
Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val 180 185 190Asp
Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val 195 200
205Ile Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser
210 215 220Leu Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser
Ala Glu225 230 235 240Val Lys Thr Val Asn Gly Ile Arg His Ile Gly
Leu Ala Ala Lys Gln 245 250 255209768DNANeisseria meningitidis
209atgagcagcg gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggt 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgc 240caaatcgaag tggacgggca
gctcattacc ttggagagtg gagagttcca agtatacaaa 300caaagccatt
ccgccttaac cgcctttcag accgagcaaa tacaagattc ggagcattcc
360gggaagatgg ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga
acatacatct 420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg
ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac ctacaccata
gatttcgccg ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc
agaactcaat gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac
gccatgccgt catcagcggt tccgtccttt acaaccaagc cgagaaaggc
660agttactccc tcggtatctt tggcggaaaa gcccaggaag ttgccggcag
cgcggaagtg 720aaaaccgtaa acggcatacg ccatatcggc cttgccgcca agcaataa
768210255PRTNeisseria meningitidis 210Met Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe Gln Thr Glu
100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala
Ala Lys Gln 245 250 255211768DNANeisseria meningitidis
211tgcagcagcg gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggt 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgc 240caaatcgaag tggacgggca
gctcattacc ttggagagtg gagagttcca agtatacaaa 300caaagccatt
ccgccttaac cgcctttcag accgagcaaa tacaagattc ggagcattcc
360gggaagatgg ttgcgaaacg ccagttcaga atcggcgaca tagcgggcga
acatacatct 420tttgacaagc ttcccgaagg cggcagggcg acatatcgcg
ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac ctacaccata
gatttcgccg ccaagcaggg aaacggcaaa 540atcgaacatt tgaaatcgcc
agaactcaat gtcgacctgg ccgccgccga tatcaagccg 600gatggaaaac
gccatgccgt catcagcggt tccgtccttt acaaccaagc cgagaaaggc
660agttactccc tcggtatctt tggcggaaaa gcccaggaag ttgccggcag
cgcggaagtg 720aaaaccgtaa acggcatacg ccatatcggt cttgccgcca agcagtaa
768212255PRTNeisseria meningitidis 212Cys Ser Ser Gly Gly Gly Gly
Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala
Pro Leu Asp His Lys Asp Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp
Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly
Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90
95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe Gln Thr Glu
100 105 110Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met Val Ala Lys
Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser
Phe Asp Lys Leu 130 135 140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr
Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly Asn Gly Lys Ile
Glu His Leu Lys Ser Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala
Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val Ile 195 200 205Ser
Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215
220Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu
Val225 230 235 240Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala
Ala Lys Gln 245 250 255213771DNANeisseria meningitidis
213tgcggatcca gcggaggggg tggtgtcgcc gccgacatcg gtgcggggct
tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa ggtttgcagt ctttgacgct
ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg gcacaaggtg
cggaaaaaac ttatggaaac 180ggtgacagcc tcaatacggg caaattgaag
aacgacaagg tcagccgttt cgactttatc 240cgccaaatcg aagtggacgg
gcagctcatt accttggaga gtggagagtt ccaagtatac 300aaacaaagcc
attccgcctt aaccgccttt cagaccgagc aaatacaaga ttcggagcat
360tccgggaaga tggttgcgaa acgccagttc agaatcggcg acatagcggg
cgaacataca 420tcttttgaca agcttcccga aggcggcagg gcgacatatc
gcgggacggc gttcggttca 480gacgatgccg gcggaaaact gacctacacc
atagatttcg ccgccaagca gggaaacggc 540aaaatcgaac atttgaaatc
gccagaactc aatgtcgacc tggccgccgc cgatatcaag 600ccggatggaa
aacgccatgc cgtcatcagc ggttccgtcc tttacaacca agccgagaaa
660ggcagttact ccctcggtat ctttggcgga aaagcccagg aagttgccgg
cagcgcggaa 720gtgaaaaccg taaacggcat acgccatatc ggtcttgccg
ccaagcagta a 771214256PRTNeisseria meningitidis 214Cys Gly Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10 15Leu Ala Asp
Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu 20 25 30Gln Ser
Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys 35 40 45Leu
Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu 50 55
60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile65
70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu Ser Gly
Glu 85 90 95Phe Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Phe
Gln Thr 100 105 110Glu Gln Ile Gln Asp Ser Glu His Ser Gly Lys Met
Val Ala Lys Arg 115 120 125Gln Phe Arg Ile Gly Asp Ile Ala Gly Glu
His Thr Ser Phe Asp Lys 130 135 140Leu Pro Glu Gly Gly Arg Ala Thr
Tyr Arg Gly Thr Ala Phe Gly Ser145 150 155 160Asp Asp Ala Gly Gly
Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys 165 170 175Gln Gly Asn
Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val 180 185 190Asp
Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg His Ala Val 195 200
205Ile Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser
210 215 220Leu Gly Ile Phe Gly Gly Lys Ala Gln Glu Val Ala Gly Ser
Ala Glu225 230 235 240Val Lys Thr Val Asn Gly Ile Arg His Ile Gly
Leu Ala Ala Lys Gln 245 250 255215768DNANeisseria meningitidis
215atgagcagcg gagggggtgg tgtcgccgcc gacatcggtg cggggcttgc
cgatgcacta 60accgcaccgc tcgaccataa agacaaaggt ttgcagtctt tgacgctgga
tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca caaggtgcgg
aaaaaactta tggaaacggt 180gacagcctca atacgggcaa attgaagaac
gacaaggtca gccgtttcga ctttatccgc
240caaatcgaag tggacgggca gctcattacc ttggagagtg gagagttcca
agtatacaaa 300caaagccatt ccgccttaac cgcctttcag accgagcaaa
tacaagattc ggagcattcc 360gggaagatgg ttgcgaaacg ccagttcaga
atcggcgaca tagcgggcga acatacatct 420tttgacaagc ttcccgaagg
cggcagggcg acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg
gaaaactgac ctacaccata gatttcgccg ccaagcaggg aaacggcaaa
540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg ccgccgccga
tatcaagccg 600gatggaaaac gccatgccgt catcagcggt tccgtccttt
acaaccaagc cgagaaaggc 660agttactccc tcggtatctt tggcggaaaa
gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa acggcatacg
ccatatcggt cttgccgcca agcagtaa 768216255PRTNeisseria meningitidis
216Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1
5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu
Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala
Leu Thr Ala Phe Gln Thr Glu 100 105 110Gln Ile Gln Asp Ser Glu His
Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg Ile Gly Asp
Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Glu Gly
Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155
160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln
165 170 175Gly Asn Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn
Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro Asp Gly Lys Arg
His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Ala Glu
Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Lys Ala Gln
Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys Thr Val Asn Gly
Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255217768DNANeisseria meningitidis 217tgcagcagcg gagggggcgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacaggca gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag tacaagactc ggagcattcc 360gggaagatgg ttgcgaaacg
tcagttcaga atcggcgaca tagcgggtga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgat ttacaccata gatttcgccg ctaagcaggg
acacggtaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatgaaaaac accatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggtatacg ccatatcggc cttgccgcca agcaataa 768218255PRTNeisseria
meningitidis 218Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Arg Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Val Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Ile Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro
Asp Glu Lys His His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys
Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255219771DNANeisseria meningitidis 219tgcggatcca gcggaggggg
cggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa ggtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc tcaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacag gcagctcatt accttggaga
gcggagagtt ccaagtgtac 300aaacaaagcc attccgcctt aaccgccctt
cagaccgagc aagtacaaga ctcggagcat 360tccgggaaga tggttgcgaa
acgtcagttc agaatcggcg acatagcggg tgaacataca 420tcttttgaca
agcttcccga aggcggcagg gcgacatatc gcgggacggc gttcggttca
480gacgatgccg gcggaaaact gatttacacc atagatttcg ccgctaagca
gggacacggt 540aaaatcgaac atttgaaatc gccagaactc aatgtcgacc
tggccgccgc cgatatcaag 600ccggatgaaa aacaccatgc cgtcatcagc
ggttccgtcc tttacaacca agccgagaaa 660ggcagttact ccctcggtat
ctttggcgga aaagcccagg aagttgccgg cagcgcggaa 720gtgaaaaccg
taaacggtat acgccatatc ggccttgccg ccaagcaata a 771220256PRTNeisseria
meningitidis 220Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Gly Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Arg
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Val Gln
Asp Ser Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Ile Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly His Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Asp Leu Ala Ala Ala Asp Ile Lys
Pro Asp Glu Lys His His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Ala Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Lys Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255221768DNANeisseria meningitidis 221atgagcagcg gagggggcgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctca atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacaggca gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag tacaagactc ggagcattcc 360gggaagatgg ttgcgaaacg
tcagttcaga atcggcgaca tagcgggtga acatacatct 420tttgacaagc
ttcccgaagg cggcagggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgat ttacaccata gatttcgccg ctaagcaggg
acacggtaaa 540atcgaacatt tgaaatcgcc agaactcaat gtcgacctgg
ccgccgccga tatcaagccg 600gatgaaaaac accatgccgt catcagcggt
tccgtccttt acaaccaagc cgagaaaggc 660agttactccc tcggtatctt
tggcggaaaa gcccaggaag ttgccggcag cgcggaagtg 720aaaaccgtaa
acggtatacg ccatatcggc cttgccgcca agcaataa 768222255PRTNeisseria
meningitidis 222Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Arg Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Val Gln Asp
Ser Glu His Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Glu Gly Gly Arg Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Ile Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Asp 180 185 190Leu Ala Ala Ala Asp Ile Lys Pro
Asp Glu Lys His His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Ala Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Lys Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Lys
Thr Val Asn Gly Ile Arg His Ile Gly Leu Ala Ala Lys Gln 245 250
255223768DNANeisseria meningitidis 223tgcagcagcg gagggggcgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt taacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctta atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggaa gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag tacaagactc ggaggattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccaaagg cggcagtgcg acatatcgcg ggacggcgtt cggttcagac
480gatgctggcg gaaaactgac ctatactata gatttcgccg ccaagcaggg
acacggcaaa 540atcgaacatt tgaaatcgcc cgaactcaat gtcgagcttg
ccaccgccta tatcaagccg 600gatgaaaaac gccatgccgt tatcagcggt
tccgtccttt acaaccaaga cgagaaaggc 660agttactccc tcggtatctt
tggcgggcaa gcccaggaag ttgccggcag cgcggaagtg 720gaaaccgcaa
acggcataca ccatatcggt cttgccgcca agcagtaa 768224255PRTNeisseria
meningitidis 224Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Gly Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Lys
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Val Gln Asp
Ser Glu Asp Ser Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Lys Gly Gly Ser Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Glu 180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro
Asp Glu Lys Arg His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Asp Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Glu
Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245 250
255225771DNANeisseria meningitidis 225tgcggatcca gcggaggggg
cggtgtcgcc gccgacatcg gtgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa ggtttgcagt ctttaacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc ttaatacggg caaattgaag aacgacaagg tcagccgctt
cgactttatc 240cgtcaaatcg aagtggacgg gaagctcatt accttggaga
gcggagagtt ccaagtgtac 300aaacaaagcc attccgcctt aaccgccctt
cagaccgagc aagtacaaga ctcggaggat 360tccgggaaga tggttgcgaa
acgccagttc agaatcggcg acatagcggg cgaacataca 420tcttttgaca
agcttcccaa aggcggcagt gcgacatatc gcgggacggc gttcggttca
480gacgatgctg gcggaaaact gacctatact atagatttcg ccgccaagca
gggacacggc 540aaaatcgaac atttgaaatc gcccgaactc aatgtcgagc
ttgccaccgc ctatatcaag 600ccggatgaaa aacgccatgc cgttatcagc
ggttccgtcc tttacaacca agacgagaaa 660ggcagttact ccctcggtat
ctttggcggg caagcccagg aagttgccgg cagcgcggaa 720gtggaaaccg
caaacggcat acaccatatc ggtcttgccg ccaagcagta a 771226256PRTNeisseria
meningitidis 226Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Gly Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Lys Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Val Gln
Asp Ser Glu Asp Ser Gly Lys Met Val Ala Lys Arg 115 120 125Gln Phe
Arg Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Lys Gly Gly Ser Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly His Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Glu Leu Ala Thr Ala Tyr Ile Lys
Pro Asp Glu Lys Arg His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Asp Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Glu Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245 250
255227768DNANeisseria meningitidis 227atgagcagcg gagggggcgg
tgtcgccgcc gacatcggtg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaggt ttgcagtctt taacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctta atacgggcaa attgaagaac gacaaggtca gccgcttcga
ctttatccgt 240caaatcgaag tggacgggaa gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag tacaagactc ggaggattcc 360gggaagatgg ttgcgaaacg
ccagttcaga atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccaaagg cggcagtgcg acatatcgcg ggacggcgtt cggttcagac
480gatgctggcg gaaaactgac ctatactata gatttcgccg ccaagcaggg
acacggcaaa 540atcgaacatt tgaaatcgcc cgaactcaat gtcgagcttg
ccaccgccta tatcaagccg 600gatgaaaaac gccatgccgt tatcagcggt
tccgtccttt acaaccaaga cgagaaaggc 660agttactccc tcggtatctt
tggcgggcaa gcccaggaag ttgccggcag cgcggaagtg 720gaaaccgcaa
acggcataca ccatatcggt cttgccgcca agcagtaa 768228255PRTNeisseria
meningitidis 228Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10
15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Gly Leu Gln
20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys
Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser
Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp
Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Lys Leu Ile Thr Leu
Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu
Thr Ala Leu Gln Thr Glu 100 105 110Gln Val Gln Asp Ser Glu Asp Ser
Gly Lys Met Val Ala Lys Arg Gln 115 120 125Phe Arg Ile Gly Asp Ile
Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Lys Gly Gly
Ser Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp
Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170
175Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Glu
180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys Arg His Ala
Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly
Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Gln Ala Gln Glu Val
Ala Gly Ser Ala Glu Val225 230 235 240Glu Thr Ala Asn Gly Ile His
His Ile Gly Leu Ala Ala Lys Gln 245 250 255229768DNANeisseria
meningitidis 229tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca agtgtacaaa
300caaagccatt ccgccttaac cgcccttcag accgagcaag aacaagatcc
agagcattcc 360gggaagatgg ttgcgaaacg ccggttcaaa atcggcgaca
tagcgggcga acatacatct 420tttgacaagc ttcccaaaga cgtcatggcg
acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac
ctatactata gattttgctg ccaaacaggg acacggcaaa 540atcgaacatt
tgaaatcgcc cgaactcaat gtcgagcttg ccaccgccta tatcaagccg
600gatgaaaaac accatgccgt catcagcggt tccgtccttt acaatcaaga
cgagaaaggc 660agttactccc tcggtatctt tggcgggcaa gcccaggaag
ttgccggcag cgcggaagtg 720gaaaccgcaa acggcataca ccatatcggt
cttgccgcca agcaataa 768230255PRTNeisseria meningitidis 230Cys Ser
Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25
30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu
35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu
Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe
Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu
Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp Pro Glu His Ser Gly
Lys Met Val Ala Lys Arg Arg 115 120 125Phe Lys Ile Gly Asp Ile Ala
Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Lys Asp Val Met
Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170
175Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Glu
180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys His His Ala
Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly
Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Gln Ala Gln Glu Val
Ala Gly Ser Ala Glu Val225 230 235 240Glu Thr Ala Asn Gly Ile His
His Ile Gly Leu Ala Ala Lys Gln 245 250 255231771DNANeisseria
meningitidis 231tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg
gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt
ctttgacgct ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg
gcacaaggtg cggaaaaaac ttatggaaac 180ggcgacagcc ttaatacggg
caaattgaag aacgacaagg tcagccgttt cgactttatc 240cgtcaaatcg
aagtggacgg gcagctcatt accttggaga gcggagagtt ccaagtgtac
300aaacaaagcc attccgcctt aaccgccctt cagaccgagc aagaacaaga
tccagagcat 360tccgggaaga tggttgcgaa acgccggttc aaaatcggcg
acatagcggg cgaacataca 420tcttttgaca agcttcccaa agacgtcatg
gcgacatatc gcgggacggc gttcggttca 480gacgatgccg gcggaaaact
gacctatact atagattttg ctgccaaaca gggacacggc 540aaaatcgaac
atttgaaatc gcccgaactc aatgtcgagc ttgccaccgc ctatatcaag
600ccggatgaaa aacaccatgc cgtcatcagc ggttccgtcc tttacaatca
agacgagaaa 660ggcagttact ccctcggtat ctttggcggg caagcccagg
aagttgccgg cagcgcggaa 720gtggaaaccg caaacggcat acaccatatc
ggtcttgccg ccaagcaata a 771232256PRTNeisseria meningitidis 232Cys
Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10
15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu
20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln Ser His Ser Ala
Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Glu Gln Asp Pro Glu His
Ser Gly Lys Met Val Ala Lys Arg 115 120 125Arg Phe Lys Ile Gly Asp
Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135 140Leu Pro Lys Asp
Val Met Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser145 150 155 160Asp
Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys 165 170
175Gln Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val
180 185 190Glu Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys His His
Ala Val 195 200 205Ile Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys
Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe Gly Gly Gln Ala Gln Glu
Val Ala Gly Ser Ala Glu225 230 235 240Val Glu Thr Ala Asn Gly Ile
His His Ile Gly Leu Ala Ala Lys Gln 245 250 255233768DNANeisseria
meningitidis 233atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca agtgtacaaa
300caaagccatt ccgccttaac cgcccttcag accgagcaag aacaagatcc
agagcattcc 360gggaagatgg ttgcgaaacg ccggttcaaa atcggcgaca
tagcgggcga acatacatct 420tttgacaagc ttcccaaaga cgtcatggcg
acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac
ctatactata gattttgctg ccaaacaggg acacggcaaa 540atcgaacatt
tgaaatcgcc cgaactcaat gtcgagcttg ccaccgccta tatcaagccg
600gatgaaaaac accatgccgt catcagcggt tccgtccttt acaatcaaga
cgagaaaggc 660agttactccc tcggtatctt tggcgggcaa gcccaggaag
ttgccggcag cgcggaagtg 720gaaaccgcaa acggcataca ccatatcggt
cttgccgcca agcaataa 768234255PRTNeisseria meningitidis 234Met Ser
Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25
30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu
35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu
Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe
Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu
Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp Pro Glu His Ser Gly
Lys Met Val Ala Lys Arg Arg 115 120 125Phe Lys Ile Gly Asp Ile Ala
Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Lys Asp Val Met
Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170
175Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Glu
180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys His His Ala
Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly
Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Gln Ala Gln Glu Val
Ala Gly Ser Ala Glu Val225 230 235 240Glu Thr Ala Asn Gly Ile His
His Ile Gly Leu Ala Ala Lys Gln 245 250 255235768DNANeisseria
meningitidis 235tgcagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca agtgtacaaa
300caaagccatt ccgccttaac cgcccttcag accgagcaag aacaagatcc
agagcattcc 360gggaagatgg ttgcgaaacg ccggttcaaa atcggcgaca
tagcgggcga acatacatct 420tttgacaagc ttcccaaaga cgtcatggcg
acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac
ctatactata gattttgctg ccaaacaggg acacggcaaa 540atcgaacatt
tgaaatcgcc cgaactcaat gtcgagcttg ccaccgccta tatcaagccg
600gatgaaaaac accatgccgt catcagcggt tccgtccttt acaatcaaga
cgagaaaggc 660agttactccc tcggtatctt tggcgggcaa gcccaggaag
ttgccggcag cgcggaagtg 720gaaaccgcaa acggcataca ccatatcggt
cttgccgcca agcaataa 768236255PRTNeisseria meningitidis 236Cys Ser
Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25
30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu
35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu
Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe
Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu
Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp Pro Glu His Ser Gly
Lys Met Val Ala Lys Arg Arg 115 120 125Phe Lys Ile Gly Asp Ile Ala
Gly Glu His Thr Ser Phe Asp Lys Leu 130 135 140Pro Lys Asp Val Met
Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170
175Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Glu
180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys His His Ala
Val Ile 195 200 205Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly
Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly Gly Gln Ala Gln Glu Val
Ala Gly Ser Ala Glu Val225 230 235 240Glu Thr Ala Asn Gly Ile His
His Ile Gly Leu Ala Ala Lys Gln 245 250 255237771DNANeisseria
meningitidis 237tgcggatcca gcggaggcgg cggtgtcgcc gccgacatcg
gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca taaagacaaa agtttgcagt
ctttgacgct ggatcagtcc 120gtcaggaaaa acgagaaact gaagctggcg
gcacaaggtg cggaaaaaac ttatggaaac 180ggcgacagcc ttaatacggg
caaattgaag aacgacaagg tcagccgttt cgactttatc 240cgtcaaatcg
aagtggacgg gcagctcatt accttggaga gcggagagtt ccaagtgtac
300aaacaaagcc attccgcctt aaccgccctt cagaccgagc aagaacaaga
tccagagcat 360tccgggaaga tggttgcgaa acgccggttc aaaatcggcg
acatagcggg cgaacataca 420tcttttgaca agcttcccaa agacgtcatg
gcgacatatc gcgggacggc gttcggttca 480gacgatgccg gcggaaaact
gacctatact atagattttg ctgccaaaca gggacacggc 540aaaatcgaac
atttgaaatc gcccgaactc aatgtcgagc ttgccaccgc ctatatcaag
600ccggatgaaa aacaccatgc cgtcatcagc ggttccgtcc tttacaatca
agacgagaaa 660ggcagttact ccctcggtat ctttggcggg caagcccagg
aagttgccgg cagcgcggaa 720gtggaaaccg caaacggcat acaccatatc
ggtcttgccg ccaagcaata a 771238256PRTNeisseria meningitidis 238Cys
Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly1 5 10
15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu
20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu
Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp
Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe
Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr
Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln Ser His Ser Ala
Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Glu Gln Asp Pro Glu His
Ser Gly Lys Met Val Ala Lys Arg 115 120 125Arg Phe Lys Ile Gly Asp
Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135 140Leu Pro Lys Asp
Val Met Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser145 150 155 160Asp
Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe Ala Ala Lys 165 170
175Gln Gly His Gly Lys Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val
180 185 190Glu Leu Ala Thr Ala Tyr Ile Lys Pro Asp Glu Lys His His
Ala Val 195 200 205Ile Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys
Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe Gly Gly Gln Ala Gln Glu
Val Ala Gly Ser Ala Glu225 230 235 240Val Glu Thr Ala Asn Gly Ile
His His Ile Gly Leu Ala Ala Lys Gln 245 250 255239768DNANeisseria
meningitidis 239atgagcagcg gaggcggcgg tgtcgccgcc gacatcggcg
cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa agacaaaagt ttgcagtctt
tgacgctgga tcagtccgtc 120aggaaaaacg agaaactgaa gctggcggca
caaggtgcgg aaaaaactta tggaaacggc 180gacagcctta atacgggcaa
attgaagaac gacaaggtca gccgtttcga ctttatccgt 240caaatcgaag
tggacgggca gctcattacc ttggagagcg gagagttcca agtgtacaaa
300caaagccatt ccgccttaac cgcccttcag accgagcaag aacaagatcc
agagcattcc 360gggaagatgg ttgcgaaacg ccggttcaaa atcggcgaca
tagcgggcga acatacatct 420tttgacaagc ttcccaaaga cgtcatggcg
acatatcgcg ggacggcgtt cggttcagac 480gatgccggcg gaaaactgac
ctatactata gattttgctg ccaaacaggg acacggcaaa 540atcgaacatt
tgaaatcgcc cgaactcaat gtcgagcttg ccaccgccta tatcaagccg
600gatgaaaaac accatgccgt catcagcggt tccgtccttt acaatcaaga
cgagaaaggc 660agttactccc tcggtatctt tggcgggcaa gcccaggaag
ttgccggcag cgcggaagtg 720gaaaccgcaa acggcataca ccatatcggt
cttgccgcca agcaataa 768240255PRTNeisseria meningitidis 240Met Ser
Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Ala Gly Leu1 5 10 15Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp Lys Ser Leu Gln 20 25
30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn Glu Lys Leu Lys Leu
35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu
Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe
Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu Glu
Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp Pro Glu His Ser Gly
Lys Met Val Ala Lys Arg Arg 115
120 125Phe Lys Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys
Leu 130 135 140Pro Lys Asp Val Met Ala Thr Tyr Arg Gly Thr Ala Phe
Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile
Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu
Lys Ser Pro Glu Leu Asn Val Glu 180 185 190Leu Ala Thr Ala Tyr Ile
Lys Pro Asp Glu Lys His His Ala Val Ile 195 200 205Ser Gly Ser Val
Leu Tyr Asn Gln Asp Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile
Phe Gly Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235
240Glu Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245
250 255241765DNANeisseria meningitidis 241tgcagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctta atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag aacaagatcc agagcattcc 360gggaagatgg ttgcgaaacg
ccggttcaaa atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccaaaga cgtcatggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctatactata gattttgctg ccaaacaggg
acacggcaaa 540atcgaacatt tgaaatcgcc cgaactcaat gtcgagcttg
ccaccgccta tatcaagccg 600gatgaaaaac accatgccgt catcagcggt
tccgtccttt acaatcaaga cgagaaaggc 660agttactccc tcggtatctt
tggcgggcaa gcccaggaag ttgccggcag cgcggaagtg 720gaaaccgcaa
acggcataca ccatatcggt cttgccgcca agcaa 765242255PRTNeisseria
meningitidis 242Cys Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp
Pro Glu His Ser Gly Lys Met Val Ala Lys Arg Arg 115 120 125Phe Lys
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Lys Asp Val Met Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Glu 180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro
Asp Glu Lys His His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Asp Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Glu
Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245 250
255243768DNANeisseria meningitidis 243tgcggatcca gcggaggcgg
cggtgtcgcc gccgacatcg gcgcggggct tgccgatgca 60ctaaccgcac cgctcgacca
taaagacaaa agtttgcagt ctttgacgct ggatcagtcc 120gtcaggaaaa
acgagaaact gaagctggcg gcacaaggtg cggaaaaaac ttatggaaac
180ggcgacagcc ttaatacggg caaattgaag aacgacaagg tcagccgttt
cgactttatc 240cgtcaaatcg aagtggacgg gcagctcatt accttggaga
gcggagagtt ccaagtgtac 300aaacaaagcc attccgcctt aaccgccctt
cagaccgagc aagaacaaga tccagagcat 360tccgggaaga tggttgcgaa
acgccggttc aaaatcggcg acatagcggg cgaacataca 420tcttttgaca
agcttcccaa agacgtcatg gcgacatatc gcgggacggc gttcggttca
480gacgatgccg gcggaaaact gacctatact atagattttg ctgccaaaca
gggacacggc 540aaaatcgaac atttgaaatc gcccgaactc aatgtcgagc
ttgccaccgc ctatatcaag 600ccggatgaaa aacaccatgc cgtcatcagc
ggttccgtcc tttacaatca agacgagaaa 660ggcagttact ccctcggtat
ctttggcggg caagcccagg aagttgccgg cagcgcggaa 720gtggaaaccg
caaacggcat acaccatatc ggtcttgccg ccaagcaa 768244256PRTNeisseria
meningitidis 244Cys Gly Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile
Gly Ala Gly1 5 10 15Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys
Asp Lys Ser Leu 20 25 30Gln Ser Leu Thr Leu Asp Gln Ser Val Arg Lys
Asn Glu Lys Leu Lys 35 40 45Leu Ala Ala Gln Gly Ala Glu Lys Thr Tyr
Gly Asn Gly Asp Ser Leu 50 55 60Asn Thr Gly Lys Leu Lys Asn Asp Lys
Val Ser Arg Phe Asp Phe Ile65 70 75 80Arg Gln Ile Glu Val Asp Gly
Gln Leu Ile Thr Leu Glu Ser Gly Glu 85 90 95Phe Gln Val Tyr Lys Gln
Ser His Ser Ala Leu Thr Ala Leu Gln Thr 100 105 110Glu Gln Glu Gln
Asp Pro Glu His Ser Gly Lys Met Val Ala Lys Arg 115 120 125Arg Phe
Lys Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys 130 135
140Leu Pro Lys Asp Val Met Ala Thr Tyr Arg Gly Thr Ala Phe Gly
Ser145 150 155 160Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
Phe Ala Ala Lys 165 170 175Gln Gly His Gly Lys Ile Glu His Leu Lys
Ser Pro Glu Leu Asn Val 180 185 190Glu Leu Ala Thr Ala Tyr Ile Lys
Pro Asp Glu Lys His His Ala Val 195 200 205Ile Ser Gly Ser Val Leu
Tyr Asn Gln Asp Glu Lys Gly Ser Tyr Ser 210 215 220Leu Gly Ile Phe
Gly Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu225 230 235 240Val
Glu Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245 250
255245765DNANeisseria meningitidis 245atgagcagcg gaggcggcgg
tgtcgccgcc gacatcggcg cggggcttgc cgatgcacta 60accgcaccgc tcgaccataa
agacaaaagt ttgcagtctt tgacgctgga tcagtccgtc 120aggaaaaacg
agaaactgaa gctggcggca caaggtgcgg aaaaaactta tggaaacggc
180gacagcctta atacgggcaa attgaagaac gacaaggtca gccgtttcga
ctttatccgt 240caaatcgaag tggacgggca gctcattacc ttggagagcg
gagagttcca agtgtacaaa 300caaagccatt ccgccttaac cgcccttcag
accgagcaag aacaagatcc agagcattcc 360gggaagatgg ttgcgaaacg
ccggttcaaa atcggcgaca tagcgggcga acatacatct 420tttgacaagc
ttcccaaaga cgtcatggcg acatatcgcg ggacggcgtt cggttcagac
480gatgccggcg gaaaactgac ctatactata gattttgctg ccaaacaggg
acacggcaaa 540atcgaacatt tgaaatcgcc cgaactcaat gtcgagcttg
ccaccgccta tatcaagccg 600gatgaaaaac accatgccgt catcagcggt
tccgtccttt acaatcaaga cgagaaaggc 660agttactccc tcggtatctt
tggcgggcaa gcccaggaag ttgccggcag cgcggaagtg 720gaaaccgcaa
acggcataca ccatatcggt cttgccgcca agcaa 765246255PRTNeisseria
meningitidis 246Met Ser Ser Gly Gly Gly Gly Val Ala Ala Asp Ile Gly
Ala Gly Leu1 5 10 15Ala Asp Ala Leu Thr Ala Pro Leu Asp His Lys Asp
Lys Ser Leu Gln 20 25 30Ser Leu Thr Leu Asp Gln Ser Val Arg Lys Asn
Glu Lys Leu Lys Leu 35 40 45Ala Ala Gln Gly Ala Glu Lys Thr Tyr Gly
Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Val
Ser Arg Phe Asp Phe Ile Arg65 70 75 80Gln Ile Glu Val Asp Gly Gln
Leu Ile Thr Leu Glu Ser Gly Glu Phe 85 90 95Gln Val Tyr Lys Gln Ser
His Ser Ala Leu Thr Ala Leu Gln Thr Glu 100 105 110Gln Glu Gln Asp
Pro Glu His Ser Gly Lys Met Val Ala Lys Arg Arg 115 120 125Phe Lys
Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys Leu 130 135
140Pro Lys Asp Val Met Ala Thr Tyr Arg Gly Thr Ala Phe Gly Ser
Asp145 150 155 160Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp Phe
Ala Ala Lys Gln 165 170 175Gly His Gly Lys Ile Glu His Leu Lys Ser
Pro Glu Leu Asn Val Glu 180 185 190Leu Ala Thr Ala Tyr Ile Lys Pro
Asp Glu Lys His His Ala Val Ile 195 200 205Ser Gly Ser Val Leu Tyr
Asn Gln Asp Glu Lys Gly Ser Tyr Ser Leu 210 215 220Gly Ile Phe Gly
Gly Gln Ala Gln Glu Val Ala Gly Ser Ala Glu Val225 230 235 240Glu
Thr Ala Asn Gly Ile His His Ile Gly Leu Ala Ala Lys Gln 245 250
255247783DNANeisseria meningitidis 247tgcagcagcg gaggcggcgg
aagcggaggc ggcggtgtca ccgccgacat cggcacgggg 60cttgccgatg cactaactgc
gccgctcgac cataaagaca aaggcttgaa atccctgaca 120ttggaagact
ccatttccca aaacggaaca ctgaccctgt cggcacaagg tgcggaaaaa
180acttatggaa acggcgacag ccttaatacg ggcaaattga agaacgacaa
ggtcagccgt 240ttcgacttta tccgtcaaat cgaagtggac gggcagctca
ttaccttgga gagcggagag 300ttccaagtgt acaaacaaag ccattccgcc
ttaaccgccc ttcagaccga gcaagaacaa 360gatccagagc attccgagaa
gatggttgcg aaacgccggt tcagaatcgg cgacatagcg 420ggcgaacata
catcttttga caagcttccc aaagacgtca tggcgacata tcgcgggacg
480gcgttcggtt cagacgatgc cggcggaaaa ctgacctata ctatagattt
tgctgccaaa 540cagggacacg gcaaaatcga acatttgaaa tcgccggaac
tcaatgtcga tctggccgtc 600gcctatatca agccggatga aaaacaccat
gccgtcatca gcggttccgt tctttacaac 660caagacgaga aaggcagtta
ctccctcggt atctttggcg aaaaagccca ggaagttgcc 720ggcagcgcgg
aagtggaaac cgcaaacggc atacaccata tcggtcttgc cgccaagcag 780taa
783248260PRTNeisseria meningitidis 248Cys Ser Ser Gly Gly Gly Gly
Ser Gly Gly Gly Gly Val Thr Ala Asp1 5 10 15Ile Gly Thr Gly Leu Ala
Asp Ala Leu Thr Ala Pro Leu Asp His Lys 20 25 30Asp Lys Gly Leu Lys
Ser Leu Thr Leu Glu Asp Ser Ile Ser Gln Asn 35 40 45Gly Thr Leu Thr
Leu Ser Ala Gln Gly Ala Glu Lys Thr Tyr Gly Asn 50 55 60Gly Asp Ser
Leu Asn Thr Gly Lys Leu Lys Asn Asp Lys Val Ser Arg65 70 75 80Phe
Asp Phe Ile Arg Gln Ile Glu Val Asp Gly Gln Leu Ile Thr Leu 85 90
95Glu Ser Gly Glu Phe Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr
100 105 110Ala Leu Gln Thr Glu Gln Glu Gln Asp Pro Glu His Ser Glu
Lys Met 115 120 125Val Ala Lys Arg Arg Phe Arg Ile Gly Asp Ile Ala
Gly Glu His Thr 130 135 140Ser Phe Asp Lys Leu Pro Lys Asp Val Met
Ala Thr Tyr Arg Gly Thr145 150 155 160Ala Phe Gly Ser Asp Asp Ala
Gly Gly Lys Leu Thr Tyr Thr Ile Asp 165 170 175Phe Ala Ala Lys Gln
Gly His Gly Lys Ile Glu His Leu Lys Ser Pro 180 185 190Glu Leu Asn
Val Asp Leu Ala Val Ala Tyr Ile Lys Pro Asp Glu Lys 195 200 205His
His Ala Val Ile Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys 210 215
220Gly Ser Tyr Ser Leu Gly Ile Phe Gly Glu Lys Ala Gln Glu Val
Ala225 230 235 240Gly Ser Ala Glu Val Glu Thr Ala Asn Gly Ile His
His Ile Gly Leu 245 250 255Ala Ala Lys Gln 260249786DNANeisseria
meningitidis 249tgcggatcca gcggaggcgg cggaagcgga ggcggcggtg
tcaccgccga catcggcacg 60gggcttgccg atgcactaac tgcgccgctc gaccataaag
acaaaggctt gaaatccctg 120acattggaag actccatttc ccaaaacgga
acactgaccc tgtcggcaca aggtgcggaa 180aaaacttatg gaaacggcga
cagccttaat acgggcaaat tgaagaacga caaggtcagc 240cgtttcgact
ttatccgtca aatcgaagtg gacgggcagc tcattacctt ggagagcgga
300gagttccaag tgtacaaaca aagccattcc gccttaaccg cccttcagac
cgagcaagaa 360caagatccag agcattccga gaagatggtt gcgaaacgcc
ggttcagaat cggcgacata 420gcgggcgaac atacatcttt tgacaagctt
cccaaagacg tcatggcgac atatcgcggg 480acggcgttcg gttcagacga
tgccggcgga aaactgacct atactataga ttttgctgcc 540aaacagggac
acggcaaaat cgaacatttg aaatcgccgg aactcaatgt cgatctggcc
600gtcgcctata tcaagccgga tgaaaaacac catgccgtca tcagcggttc
cgttctttac 660aaccaagacg agaaaggcag ttactccctc ggtatctttg
gcgaaaaagc ccaggaagtt 720gccggcagcg cggaagtgga aaccgcaaac
ggcatacacc atatcggtct tgccgccaag 780cagtaa 786250261PRTNeisseria
meningitidis 250Cys Gly Ser Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly
Val Thr Ala1 5 10 15Asp Ile Gly Thr Gly Leu Ala Asp Ala Leu Thr Ala
Pro Leu Asp His 20 25 30Lys Asp Lys Gly Leu Lys Ser Leu Thr Leu Glu
Asp Ser Ile Ser Gln 35 40 45Asn Gly Thr Leu Thr Leu Ser Ala Gln Gly
Ala Glu Lys Thr Tyr Gly 50 55 60Asn Gly Asp Ser Leu Asn Thr Gly Lys
Leu Lys Asn Asp Lys Val Ser65 70 75 80Arg Phe Asp Phe Ile Arg Gln
Ile Glu Val Asp Gly Gln Leu Ile Thr 85 90 95Leu Glu Ser Gly Glu Phe
Gln Val Tyr Lys Gln Ser His Ser Ala Leu 100 105 110Thr Ala Leu Gln
Thr Glu Gln Glu Gln Asp Pro Glu His Ser Glu Lys 115 120 125Met Val
Ala Lys Arg Arg Phe Arg Ile Gly Asp Ile Ala Gly Glu His 130 135
140Thr Ser Phe Asp Lys Leu Pro Lys Asp Val Met Ala Thr Tyr Arg
Gly145 150 155 160Thr Ala Phe Gly Ser Asp Asp Ala Gly Gly Lys Leu
Thr Tyr Thr Ile 165 170 175Asp Phe Ala Ala Lys Gln Gly His Gly Lys
Ile Glu His Leu Lys Ser 180 185 190Pro Glu Leu Asn Val Asp Leu Ala
Val Ala Tyr Ile Lys Pro Asp Glu 195 200 205Lys His His Ala Val Ile
Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu 210 215 220Lys Gly Ser Tyr
Ser Leu Gly Ile Phe Gly Glu Lys Ala Gln Glu Val225 230 235 240Ala
Gly Ser Ala Glu Val Glu Thr Ala Asn Gly Ile His His Ile Gly 245 250
255Leu Ala Ala Lys Gln 260251783DNANeisseria meningitidis
251atgagcagcg gaggcggcgg aagcggaggc ggcggtgtca ccgccgacat
cggcacgggg 60cttgccgatg cactaactgc gccgctcgac cataaagaca aaggcttgaa
atccctgaca 120ttggaagact ccatttccca aaacggaaca ctgaccctgt
cggcacaagg tgcggaaaaa 180acttatggaa acggcgacag ccttaatacg
ggcaaattga agaacgacaa ggtcagccgt 240ttcgacttta tccgtcaaat
cgaagtggac gggcagctca ttaccttgga gagcggagag 300ttccaagtgt
acaaacaaag ccattccgcc ttaaccgccc ttcagaccga gcaagaacaa
360gatccagagc attccgagaa gatggttgcg aaacgccggt tcagaatcgg
cgacatagcg 420ggcgaacata catcttttga caagcttccc aaagacgtca
tggcgacata tcgcgggacg 480gcgttcggtt cagacgatgc cggcggaaaa
ctgacctata ctatagattt tgctgccaaa 540cagggacacg gcaaaatcga
acatttgaaa tcgccggaac tcaatgtcga tctggccgtc 600gcctatatca
agccggatga aaaacaccat gccgtcatca gcggttccgt tctttacaac
660caagacgaga aaggcagtta ctccctcggt atctttggcg aaaaagccca
ggaagttgcc 720ggcagcgcgg aagtggaaac cgcaaacggc atacaccata
tcggtcttgc cgccaagcag 780taa 783252260PRTNeisseria meningitidis
252Met Ser Ser Gly Gly Gly Gly Ser Gly Gly Gly Gly Val Thr Ala Asp1
5 10 15Ile Gly Thr Gly Leu Ala Asp Ala Leu Thr Ala Pro Leu Asp His
Lys 20 25 30Asp Lys Gly Leu Lys Ser Leu Thr Leu Glu Asp Ser Ile Ser
Gln Asn 35 40 45Gly Thr Leu Thr Leu Ser Ala Gln Gly Ala Glu Lys Thr
Tyr Gly Asn 50 55 60Gly Asp Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp
Lys Val Ser Arg65 70 75 80Phe Asp Phe Ile Arg Gln Ile Glu Val Asp
Gly Gln Leu Ile Thr Leu 85 90 95Glu Ser Gly Glu Phe Gln Val Tyr Lys
Gln Ser His Ser Ala Leu Thr 100 105 110Ala Leu Gln Thr Glu Gln Glu
Gln Asp Pro Glu His Ser Glu Lys Met 115 120 125Val Ala Lys Arg Arg
Phe Arg Ile Gly Asp Ile Ala Gly Glu His Thr 130 135 140Ser Phe Asp
Lys Leu Pro Lys Asp Val Met Ala Thr Tyr Arg Gly Thr145 150 155
160Ala Phe Gly Ser Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr Ile Asp
165 170 175Phe Ala Ala Lys Gln Gly His Gly Lys Ile Glu His Leu Lys
Ser Pro 180 185 190Glu
Leu Asn Val Asp Leu Ala Val Ala Tyr Ile Lys Pro Asp Glu Lys 195 200
205His His Ala Val Ile Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys
210 215 220Gly Ser Tyr Ser Leu Gly Ile Phe Gly Glu Lys Ala Gln Glu
Val Ala225 230 235 240Gly Ser Ala Glu Val Glu Thr Ala Asn Gly Ile
His His Ile Gly Leu 245 250 255Ala Ala Lys Gln
260253390DNANeisseria meningitidis 253gacagcctga taaaccaacg
ctccttcctt gtcagcggtt tgggcggaga acataccgcc 60ttcaaccaac tgcctgacgg
caaagccgag tatcacggca aagcattcag ctccgacgat 120gctggcggaa
aactgaccta taccatagat ttcgccgcca aacagggaca cggcaaaatc
180gaacacctga aaacacccga gcaaaatgtc gagcttgccg ccgccgaact
caaagcagat 240gaaaaatcac acgccgtcat tttgggcgac acgcgctacg
gcagcgaaga aaaaggcact 300taccacctcg cccttttcgg cgaccgcgcc
caagaaatcg ccggctcggc aaccgtgaag 360ataggggaaa aggttcacga
aatcggcatc 39025410PRTNeisseria meningitidisMISC_FEATURE(5)..(5)Xaa
equals any of the naturally occurring L-amino acids 254Ala Asp Ile
Gly Xaa Gly Leu Ala Asp Ala1 5 1025510PRTNeisseria
meningitidisMISC_FEATURE(3)..(3)Xaa equals any of the naturally
occurring L-amino acids 255Ile Gly Xaa Gly Leu Ala Asp Ala Leu Thr1
5 1025610PRTNeisseria meningitidis 256Ser Leu Asn Thr Gly Lys Leu
Lys Asn Asp1 5 1025717PRTNeisseria
meningitidisMISC_FEATURE(12)..(12)Xaa equals any of the naturally
occurring L-amino acids 257Ser Leu Asn Thr Gly Lys Leu Lys Asn Asp
Lys Xaa Ser Arg Phe Asp1 5 10 15Phe2589PRTNeisseria
meningitidisMISC_FEATURE(6)..(6)Xaa equals any of the naturally
occurring L-amino acids 258Ser Gly Glu Phe Gln Xaa Tyr Lys Gln1
52598PRTNeisseria meningitidisMISC_FEATURE(6)..(6)Xaa equals any of
the naturally occurring L-amino acids 259Ile Glu His Leu Lys Xaa
Pro Glu1 526010PRTNeisseria meningitidisMISC_FEATURE(10)..(10)Xaa
equals any of the naturally occurring L-amino acids 260Gly Gly Gly
Val Ala Ala Asp Ile Gly Xaa1 5 102619PRTNeisseria meningitidis
261Ser Gly Glu Phe Gln Ile Tyr Lys Gln1 526210PRTNeisseria
meningitidis 262His Ser Ala Val Val Ala Leu Gln Ile Glu1 5
1026310PRTNeisseria meningitidis 263Glu Lys Ile Asn Asn Pro Asp Lys
Ile Asp1 5 1026410PRTNeisseria meningitidis 264Ser Leu Ile Asn Gln
Arg Ser Phe Leu Val1 5 1026510PRTNeisseria meningitidis 265Ser Gly
Leu Gly Gly Glu His Thr Ala Phe1 5 1026610PRTNeisseria meningitidis
266Gly Glu His Thr Ala Phe Asn Gln Leu Pro1 5 1026711PRTNeisseria
meningitidis 267Ser Phe Leu Val Ser Gly Leu Gly Gly Glu His1 5
1026834PRTNeisseria meningitidis 268Glu Lys Ile Asn Asn Pro Asp Lys
Ile Asp Ser Leu Ile Asn Gln Arg1 5 10 15Ser Phe Leu Val Ser Gly Leu
Gly Gly Glu His Thr Ala Phe Asn Gln 20 25 30Leu
Pro26910PRTNeisseria meningitidis 269Gly Lys Ala Glu Tyr His Gly
Lys Ala Phe1 5 1027010PRTNeisseria meningitidis 270Tyr His Gly Lys
Ala Phe Ser Ser Asp Asp1 5 1027114PRTNeisseria meningitidis 271Gly
Lys Ala Glu Tyr His Gly Lys Ala Phe Ser Ser Asp Asp1 5
1027210PRTNeisseria meningitidis 272Ile Glu His Leu Lys Thr Pro Glu
Gln Asn1 5 1027310PRTNeisseria meningitidis 273Lys Thr Pro Glu Gln
Asn Val Glu Leu Ala1 5 1027414PRTNeisseria meningitidis 274Ile Glu
His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu Ala1 5
1027510PRTNeisseria meningitidis 275Ala Glu Leu Lys Ala Asp Glu Lys
Ser His1 5 1027610PRTNeisseria meningitidis 276Ala Val Ile Leu Gly
Asp Thr Arg Tyr Gly1 5 1027720PRTNeisseria meningitidis 277Ala Glu
Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu Gly Asp1 5 10 15Thr
Arg Tyr Gly 2027810PRTNeisseria meningitidis 278Glu Glu Lys Gly Thr
Tyr His Leu Ala Leu1 5 1027910PRTNeisseria meningitidis 279Leu Ile
Thr Leu Glu Ser Gly Glu Phe Gln1 5 1028010PRTNeisseria meningitidis
280Ser Ala Leu Thr Ala Leu Gln Thr Glu Gln1 5 1028110PRTNeisseria
meningitidis 281Phe Gln Val Tyr Lys Gln Ser His Ser Ala1 5
1028226PRTNeisseria meningitidis 282Leu Ile Thr Leu Glu Ser Gly Glu
Phe Gln Val Tyr Lys Gln Ser His1 5 10 15Ser Ala Leu Thr Ala Leu Gln
Thr Glu Gln 20 2528310PRTNeisseria meningitidis 283Ile Gly Asp Ile
Ala Gly Glu His Thr Ser1 5 1028410PRTNeisseria meningitidis 284Glu
His Thr Ser Phe Asp Lys Leu Pro Lys1 5 1028516PRTNeisseria
meningitidis 285Ile Gly Asp Ile Ala Gly Glu His Thr Ser Phe Asp Lys
Leu Pro Lys1 5 10 1528610PRTNeisseria meningitidis 286Ala Thr Tyr
Arg Gly Thr Ala Phe Gly Ser1 5 1028710PRTNeisseria meningitidis
287Asp Asp Ala Gly Gly Lys Leu Thr Tyr Thr1 5 1028810PRTNeisseria
meningitidis 288Ile Asp Phe Ala Ala Lys Gln Gly His Gly1 5
1028910PRTNeisseria meningitidis 289Lys Ile Glu His Leu Lys Ser Pro
Glu Leu1 5 1029042PRTNeisseria meningitidis 290Ala Thr Tyr Arg Gly
Thr Ala Phe Gly Ser Asp Asp Ala Gly Gly Lys1 5 10 15Leu Thr Tyr Thr
Ile Asp Phe Ala Ala Lys Gln Gly His Gly Lys Ile 20 25 30Glu His Leu
Lys Ser Pro Glu Leu Asn Val 35 4029110PRTNeisseria meningitidis
291His Ala Val Ile Ser Gly Ser Val Leu Tyr1 5 1029210PRTNeisseria
meningitidis 292Lys Gly Ser Tyr Ser Leu Gly Ile Phe Gly1 5
1029310PRTNeisseria meningitidis 293Val Leu Tyr Asn Gln Asp Glu Lys
Gly Ser1 5 1029424PRTNeisseria meningitidis 294His Ala Val Ile Ser
Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly1 5 10 15Ser Tyr Ser Leu
Gly Ile Phe Gly 2029510PRTNeisseria meningitidis 295Ala Gln Glu Val
Ala Gly Ser Ala Glu Val1 5 1029610PRTNeisseria meningitidis 296Ile
His His Ile Gly Leu Ala Ala Lys Gln1 5 1029710PRTNeisseria
meningitidis 297Val Glu Thr Ala Asn Gly Ile His His Ile1 5
1029825PRTNeisseria meningitidis 298Ala Gln Glu Val Ala Gly Ser Ala
Glu Val Glu Thr Ala Asn Gly Ile1 5 10 15His His Ile Gly Leu Ala Ala
Lys Gln 20 2529922PRTNeisseria meningitidis 299Val Ala Gly Ser Ala
Glu Val Glu Thr Ala Asn Gly Ile His His Ile1 5 10 15Gly Leu Ala Ala
Lys Gln 20300254PRTNeisseria meningitidisMISC_FEATURE(9)..(9)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(14)..(14)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(22)..(22)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(24)..(24)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(26)..(26)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(30)..(30)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(32)..(32)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(37)..(37)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(38)..(38)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(40)..(40)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(41)..(41)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(42)..(42)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(44)..(44)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(45)..(45)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(47)..(47)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(49)..(49)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(57)..(57)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(58)..(58)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(59)..(59)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(73)..(73)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(79)..(79)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(80)..(80)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(81)..(81)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(83)..(83)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(87)..(87)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(88)..(88)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(92)..(92)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(98)..(98)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(102)..(102)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(106)..(106)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(107)..(107)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(111)..(111)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(113)..(113)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(114)..(114)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(115)..(115)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(116)..(116)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(117)..(117)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(118)..(118)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(119)..(119)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(120)..(120)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(121)..(121)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(122)..(122)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(123)..(123)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(124)..(124)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(125)..(125)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(126)..(126)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(128)..(128)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(130)..(130)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(131)..(131)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(132)..(132)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(133)..(133)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(134)..(134)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(135)..(135)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(140)..(140)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(142)..(142)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(143)..(143)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(146)..(146)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(147)..(147)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(148)..(148)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(150)..(150)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(152)..(152)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(154)..(154)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(157)..(157)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(161)..(161)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(162)..(162)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(164)..(164)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(166)..(166)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(168)..(168)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(172)..(172)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(173)..(173)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(177)..(177)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(179)..(179)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(185)..(185)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(188)..(188)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(191)..(191)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(194)..(194)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(195)..(195)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(196)..(196)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(197)..(197)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(199)..(199)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(203)..(203)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(208)..(208)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(210)..(210)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(211)..(211)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(212)..(212)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(214)..(214)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(215)..(215)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(216)..(216)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(220)..(220)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(222)..(222)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(224)..(224)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(225)..(225)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(226)..(226)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(228)..(228)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(229)..(229)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(233)..(233)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(236)..(236)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(238)..(238)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(240)..(240)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(241)..(241)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(242)..(242)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(243)..(243)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(244)..(244)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(245)..(245)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(247)..(247)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(249)..(249)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(250)..(250)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(252)..(252)Xaa equals any of
the naturally occurring L-amino acids 300Cys Ser Ser Gly Gly Gly
Gly Val Xaa Ala Asp Ile Gly Xaa Gly Leu1 5 10 15Ala Asp Ala Leu Thr
Xaa Pro Xaa Asp Xaa Lys Asp Lys Xaa Leu Xaa 20 25 30Ser Leu Thr Leu
Xaa Xaa Ser Xaa Xaa Xaa Asn Xaa Xaa Leu Xaa Leu 35 40 45Xaa Ala Gln
Gly Ala Glu Lys Thr Xaa Xaa Xaa Gly Asp Ser Leu Asn 50 55 60Thr Gly
Lys Leu Lys Asn Asp Lys Xaa Ser Arg Phe Asp Phe Xaa Xaa65 70 75
80Xaa Ile Xaa Val Asp
Gly Xaa Xaa Ile Thr Leu Xaa Ser Gly Glu Phe 85 90 95Gln Xaa Tyr Lys
Gln Xaa His Ser Ala Xaa Xaa Ala Leu Gln Xaa Glu 100 105 110Xaa Xaa
Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Arg Xaa 115 120
125Phe Xaa Xaa Xaa Xaa Xaa Xaa Gly Glu His Thr Xaa Phe Xaa Xaa Leu
130 135 140Pro Xaa Xaa Xaa Ala Xaa Tyr Xaa Gly Xaa Ala Phe Xaa Ser
Asp Asp145 150 155 160Xaa Xaa Gly Xaa Leu Xaa Tyr Xaa Ile Asp Phe
Xaa Xaa Lys Gln Gly 165 170 175Xaa Gly Xaa Ile Glu His Leu Lys Xaa
Pro Glu Xaa Asn Val Xaa Leu 180 185 190Ala Xaa Xaa Xaa Xaa Lys Xaa
Asp Glu Lys Xaa His Ala Val Ile Xaa 195 200 205Gly Xaa Xaa Xaa Tyr
Xaa Xaa Xaa Glu Lys Gly Xaa Tyr Xaa Leu Xaa 210 215 220Xaa Xaa Gly
Xaa Xaa Ala Gln Glu Xaa Ala Gly Xaa Ala Xaa Val Xaa225 230 235
240Xaa Xaa Xaa Xaa Xaa His Xaa Ile Xaa Xaa Ala Xaa Lys Gln 245
250301254PRTNeisseria meningitidisMISC_FEATURE(14)..(14)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(22)..(22)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(24)..(24)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(26)..(26)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(30)..(30)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(32)..(32)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(37)..(37)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(38)..(38)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(40)..(40)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(41)..(41)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(42)..(42)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(44)..(44)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(45)..(45)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(47)..(47)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(49)..(49)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(57)..(57)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(58)..(58)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(59)..(59)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(73)..(73)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(79)..(79)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(80)..(80)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(81)..(81)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(83)..(83)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(88)..(88)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(92)..(92)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(102)..(102)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(146)..(146)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(161)..(161)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(162)..(162)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(164)..(164)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(166)..(166)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(168)..(168)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(172)..(172)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(173)..(173)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(177)..(177)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(179)..(179)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(194)..(194)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(215)..(215)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(226)..(226)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(236)..(236)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(242)..(242)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(249)..(249)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(252)..(252)Xaa
equals any of the naturally occurring L-amino acids 301Cys Ser Ser
Gly Gly Gly Gly Val Ala Ala Asp Ile Gly Xaa Gly Leu1 5 10 15Ala Asp
Ala Leu Thr Xaa Pro Xaa Asp Xaa Lys Asp Lys Xaa Leu Xaa 20 25 30Ser
Leu Thr Leu Xaa Xaa Ser Xaa Xaa Xaa Asn Xaa Xaa Leu Xaa Leu 35 40
45Xaa Ala Gln Gly Ala Glu Lys Thr Xaa Xaa Xaa Gly Asp Ser Leu Asn
50 55 60Thr Gly Lys Leu Lys Asn Asp Lys Xaa Ser Arg Phe Asp Phe Xaa
Xaa65 70 75 80Xaa Ile Xaa Val Asp Gly Gln Xaa Ile Thr Leu Xaa Ser
Gly Glu Phe 85 90 95Gln Ile Tyr Lys Gln Xaa His Ser Ala Val Val Ala
Leu Gln Ile Glu 100 105 110Lys Ile Asn Asn Pro Asp Lys Ile Asp Ser
Leu Ile Asn Gln Arg Ser 115 120 125Phe Leu Val Ser Gly Leu Gly Gly
Glu His Thr Ala Phe Asn Gln Leu 130 135 140Pro Xaa Gly Lys Ala Glu
Tyr His Gly Lys Ala Phe Ser Ser Asp Asp145 150 155 160Xaa Xaa Gly
Xaa Leu Xaa Tyr Xaa Ile Asp Phe Xaa Xaa Lys Gln Gly 165 170 175Xaa
Gly Xaa Ile Glu His Leu Lys Thr Pro Glu Gln Asn Val Glu Leu 180 185
190Ala Xaa Ala Glu Leu Lys Ala Asp Glu Lys Ser His Ala Val Ile Leu
195 200 205Gly Asp Thr Arg Tyr Gly Xaa Glu Glu Lys Gly Thr Tyr His
Leu Ala 210 215 220Leu Xaa Gly Asp Arg Ala Gln Glu Ile Ala Gly Xaa
Ala Thr Val Lys225 230 235 240Ile Xaa Glu Lys Val His Glu Ile Xaa
Ile Ala Xaa Lys Gln 245 250302255PRTNeisseria
meningitidisMISC_FEATURE(9)..(9)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(14)..(14)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(30)..(30)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(32)..(32)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(37)..(37)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(38)..(38)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(40)..(40)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(41)..(41)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(42)..(42)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(44)..(44)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(45)..(45)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(47)..(47)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(49)..(49)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(87)..(87)Xaa equals any of the
naturally occurring L-amino acidsMISC_FEATURE(114)..(114)Xaa equals
any of the naturally occurring L-amino
acidsMISC_FEATURE(117)..(117)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(119)..(119)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(121)..(121)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(128)..(128)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(130)..(130)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(147)..(147)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(148)..(148)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(149)..(149)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(192)..(192)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(195)..(195)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(196)..(196)Xaa equals any of
the naturally occurring L-amino acidsMISC_FEATURE(204)..(204)Xaa
equals any of the naturally occurring L-amino
acidsMISC_FEATURE(229)..(229)Xaa equals any of the naturally
occurring L-amino acidsMISC_FEATURE(230)..(230)Xaa equals any of
the naturally occurring L-amino acids 302Cys Ser Ser Gly Gly Gly
Gly Val Xaa Ala Asp Ile Gly Xaa Gly Leu1 5 10 15Ala Asp Ala Leu Thr
Ala Pro Leu Asp His Lys Asp Lys Xaa Leu Xaa 20 25 30Ser Leu Thr Leu
Xaa Xaa Ser Xaa Xaa Xaa Asn Xaa Xaa Leu Xaa Leu 35 40 45Xaa Ala Gln
Gly Ala Glu Lys Thr Tyr Gly Asn Gly Asp Ser Leu Asn 50 55 60Thr Gly
Lys Leu Lys Asn Asp Lys Val Ser Arg Phe Asp Phe Ile Arg65 70 75
80Gln Ile Glu Val Asp Gly Xaa Leu Ile Thr Leu Glu Ser Gly Glu Phe
85 90 95Gln Val Tyr Lys Gln Ser His Ser Ala Leu Thr Ala Leu Gln Thr
Glu 100 105 110Gln Xaa Gln Asp Xaa Glu Xaa Ser Xaa Lys Met Val Ala
Lys Arg Xaa 115 120 125Phe Xaa Ile Gly Asp Ile Ala Gly Glu His Thr
Ser Phe Asp Lys Leu 130 135 140Pro Lys Xaa Xaa Xaa Ala Thr Tyr Arg
Gly Thr Ala Phe Gly Ser Asp145 150 155 160Asp Ala Gly Gly Lys Leu
Thr Tyr Thr Ile Asp Phe Ala Ala Lys Gln 165 170 175Gly His Gly Lys
Ile Glu His Leu Lys Ser Pro Glu Leu Asn Val Xaa 180 185 190Leu Ala
Xaa Xaa Tyr Ile Lys Pro Asp Glu Lys Xaa His Ala Val Ile 195 200
205Ser Gly Ser Val Leu Tyr Asn Gln Asp Glu Lys Gly Ser Tyr Ser Leu
210 215 220Gly Ile Phe Gly Xaa Xaa Ala Gln Glu Val Ala Gly Ser Ala
Glu Val225 230 235 240Glu Thr Ala Asn Gly Ile His His Ile Gly Leu
Ala Ala Lys Gln 245 250 25530331DNAArtificial SequencePrimer
303gcgcggatcc ttactgcttg gcggcaagac c 3130423DNAArtificial
SequencePrimer 304ctattctgca tatgactagg agc 2330521DNAArtificial
SequencePrimer 305agcagcggag gcggcggtgt c 2130621DNAArtificial
SequencePrimer 306tgccgatgca ctaaccgcac c 2130721DNAArtificial
SequencePrimer 307cgtttcgcaa ccatcttccc g 2130844DNAArtificial
SequencePrimer 308gagatctcac tcactcatta ctgcttggcg gcaagaccga tatg
4430929DNAArtificial SequencePrimer 309gcggatccag cggagggggt
ggtgtcgcc 2931035DNAArtificial SequencePrimer 310gcgcatgctt
actgcttggc ggcaagaccg atatg 3531126DNAArtificial SequencePrimer
311gcggatccag cggaggcggc ggaagc 2631265DNAArtificial
SequencePrimermisc_feature(46)..(46)"Y" equals C or
Tmisc_feature(49)..(49)"W" equals A or T 312gcgcagatct catatgagca
gcggaggggg tggtgtcgcc gccgayatwg gtgcggggct 60tgccg
6531319DNAArtificial SequencePrimer 313ctattctgcg tatgactag
1931422DNAArtificial SequencePrimer 314gtccgaacgg taaattatcg tg
2231529DNAArtificial SequencePrimer 315gcggatccag cggaggcggc
ggtgtcgcc 2931634DNAArtificial SequencePrimer 316gagatctcat
atgagcagcg gaggcggcgg aagc 3431716DNAArtificial SequencePrimer
317gacagcctga taaacc 1631819DNAArtificial SequencePrimer
318gatgccgatt tcgtgaacc 1931927DNAArtificial SequencePrimer
319gcgcatgcct actgtttgcc ggcgatg 2732044DNAArtificial
SequencePrimer 320gagatctcac tcactcacta ctgtttgccg gcgatgccga tttc
4432170DNAArtificial SequencePrimer 321gcgcagatct catatgagca
gcggaggcgg cggaagcgga ggcggcggtg tcaccgccga 60cataggcacg
7032259DNAArtificial SequenceLeader 322atgaaaacaa cgttaaaaat
gaccgcactt gcggctcttt ctgcttttgt tttagctgg 5932375DNAArtificial
SequenceLeader 323atgactagga gcaaacctgt gaaccgaact gccttctgct
gcctttccct gaccgccgcc 60ctgattctga ccgcc 7532475DNAArtificial
SequenceLeader 324atgactagga gcaaacctgt gaaccgaact gccttctgct
gcttttctct gaccgccgcc 60ctgattctga ccgcc 7532575DNAArtificial
SequenceLeader 325atgactagga gcaaacctgt gaaccgaact accttctgtt
gcctttctct gaccgccgcc 60ctgattctga ccgcc 7532675DNAArtificial
SequenceLeader 326atgactagga gtaaacctgt gaatcgaact gccttctgct
gcctttctct gaccactgcc 60ctgattctga ccgcc 75327335PRTNeisseria
meningitidis 327Cys Ser Pro Ala Ala Asp Ser Asn His Pro Ser Gly Gln
Asn Ala Pro1 5 10 15Ala Asn Thr Glu Ser Asp Gly Lys Asn Ile Thr Leu
Leu Asn Ala Ser 20 25 30Tyr Asp Val Ala Arg Asp Phe Tyr Lys Glu Tyr
Asn Pro Leu Phe Ile 35 40 45Lys Thr Tyr Gln Ser Glu His Pro Gly Thr
Ser Val Ser Ile Gln Gln 50 55 60Ser His Gly Gly Ser Ser Lys Gln Ala
Leu Ser Val Ala Asn Gly Leu65 70 75 80Gln Ala Asp Val Val Thr Met
Asn Gln Ser Ser Asp Ile Asp Leu Leu 85 90 95Glu Lys Lys Gly Leu Val
Glu Lys Gly Trp Gln Gln Ala Leu Pro Asp 100 105 110His Ala Ala Pro
Tyr Thr Ser Thr Met Val Phe Leu Val Arg Lys Asn 115 120 125Asn Pro
Lys Gln Ile Arg Asp Trp Asn Asp Leu Ala Lys Asp Gly Val 130 135
140Asn Ile Val Ile Ala Asn Pro Lys Thr Ser Gly Asn Gly Arg Tyr
Ala145 150 155 160Phe Leu Gly Ala Tyr Gly Tyr Gly Leu Lys Thr Thr
Asn Gly Asn Glu 165 170 175Gln Glu Ala Gln Lys Leu Val Ala Ser Ile
Leu Lys Asn Thr Pro Val 180 185 190Phe Glu Asn Gly Gly Arg Ala Ala
Thr Thr Thr Phe Thr Gln Arg Asn 195 200 205Ile Gly Asp Val Leu Ile
Thr Phe Glu Asn Glu Ala Asn Tyr Val Ser 210 215 220Lys Lys Leu Thr
Gln Gly Gln Phe Glu Ile Val Tyr Pro Ser Tyr Thr225 230 235 240Ile
Ser Ala Glu Ser Pro Val Ala Val Val Asn Ser Val Val Ala Lys 245 250
255Lys Gly Thr Gln Lys Thr Ala Arg Ala Tyr Leu Glu Tyr Leu Trp Ser
260 265 270Glu Pro Ala Gln Glu Leu Ala Ala Ser Leu Tyr Leu Arg Pro
Arg Asn 275 280 285Pro Glu Val Leu Ala Arg His Lys Ala Asp Phe Pro
Asp Leu Asp Thr 290 295 300Phe Ser Pro Glu Glu Lys Phe Gly Gly Trp
Asp Asn Ile Met Lys Thr305 310 315 320Tyr Phe Ala Asp Gly Gly Ile
Phe Asp Arg Leu Thr Ala Gln Lys 325 330 33532868PRTNeisseria
meningitidis 328Cys Ala Gly Thr Trp Glu Gly Ala Lys Gln Asp Thr Ala
Arg Asn Leu1 5 10 15Asp Lys Thr Gln Ala Ala Ala Glu Arg Ala Ala Glu
Gln Thr Gly Asn 20 25 30Ala Val Glu Lys Gly Trp Asp Lys Thr Lys Glu
Ala Val Lys Lys Gly 35 40 45Gly Asn Ala Val Gly Arg Gly Ile Ser His
Leu Gly Gly Lys Ile Glu 50 55 60Asn Ala Thr Glu6532921PRTNeisseria
meningitidis 329Cys Met Lys Thr Thr Leu Lys Met Thr Ala Leu Ala Ala
Leu Ser Ala1 5 10 15Phe Val Leu Ala Gly 20
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