| Patent | Date |
|---|
Nucleic Acid Binding Domains and Methods of Use Thereof
App 20220306699 - Stamatoyannopoulos; John A. ; et al. | 2022-09-29 |
Compositions and Methods for Modulation of Gene Expression
App 20220290188 - Urnov; Fyodor ; et al. | 2022-09-15 |
Methods and compositions for targeted cleavage and recombination
Grant 11,311,574 - Holmes , et al. April 26, 2 | 2022-04-26 |
Methods and compositions for modulating PD1
Grant 11,235,026 - Gregory , et al. February 1, 2 | 2022-02-01 |
Gapped And Tunable Repeat Units For Use In Genome Editing And Gene Regulation Compositions
App 20210371847 - Urnov; Fyodor ; et al. | 2021-12-02 |
Nuclease-mediated Regulation Of Gene Expression
App 20210348143 - Orkin; Stuart H. ; et al. | 2021-11-11 |
Targeted modification of malate dehydrogenase
Grant 11,085,092 - Shukla , et al. August 10, 2 | 2021-08-10 |
Nuclease-mediated regulation of gene expression
Grant 11,021,696 - Orkin , et al. June 1, 2 | 2021-06-01 |
Methods For Assessing Specificity Of Cell Engineering Tools
App 20210147922 - Urnov; Fyodor ; et al. | 2021-05-20 |
Animal Pathogen-derived Polypeptides And Uses Thereof For Genetic Engineering
App 20210115093 - Urnov; Fyodor ; et al. | 2021-04-22 |
Methods And Compositions For Modification Of A Hla Locus
App 20210054046 - Collingwood; Trevor ; et al. | 2021-02-25 |
Modulation of stem cells using zinc finger proteins
Grant 10,888,589 - Wolffe , et al. January 12, 2 | 2021-01-12 |
Methods and compositions for modification of a HLA locus
Grant 10,858,416 - Collingwood , et al. December 8, 2 | 2020-12-08 |
Methods And Compositions For Targeted Cleavage And Recombination
App 20200297762 - Holmes; Michael C. ; et al. | 2020-09-24 |
Targeted Deletion Of Cellular Dna Sequences
App 20200291424 - Guschin; Dmitry ; et al. | 2020-09-17 |
Methods and compositions for targeted cleavage and recombination
Grant 10,675,302 - Holmes , et al. | 2020-06-09 |
Targeted deletion of cellular DNA sequences
Grant 10,669,557 - Guschin , et al. | 2020-06-02 |
Optimized non-canonical zinc finger proteins
Grant 10,662,434 - Cai , et al. | 2020-05-26 |
Targeted Modification Of Malate Dehydrogenase
App 20190327928 - Shukla; Vipula ; et al. | 2019-10-31 |
Targeted modification of malate dehydrogenase
Grant 10,358,684 - Shukla , et al. | 2019-07-23 |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
Grant 10,344,289 - Gupta , et al. July 9, 2 | 2019-07-09 |
Novel Dna-binding Proteins And Uses Thereof
App 20190169640 - Gregory; Philip D. ; et al. | 2019-06-06 |
Targeted genomic alteration
Grant 10,260,062 - Ainley , et al. | 2019-04-16 |
DNA-binding proteins and uses thereof
Grant 10,253,333 - Gregory , et al. | 2019-04-09 |
Genome Editing In Rats Using Zinc-finger Nucleases
App 20190062789 - Cui; Xiaoxia ; et al. | 2019-02-28 |
Methods and compositions for treatment of a genetic condition
Grant 10,196,651 - Conway , et al. Fe | 2019-02-05 |
Methods and compositions for treatment of a genetic condition
Grant 10,196,652 - Conway , et al. Fe | 2019-02-05 |
Methods and compositions for nuclease-mediated targeted integration of transgenes
Grant 10,174,331 - Cost , et al. J | 2019-01-08 |
Methods And Compositions For Modulating Pd1
App 20180326000 - Gregory; Philip D. ; et al. | 2018-11-15 |
Methods And Compositions For Modification Of A Hla Locus
App 20180319864 - Collingwood; Trevor ; et al. | 2018-11-08 |
Methods and compositions for modification of a HLA locus
Grant 10,072,062 - Collingwood , et al. September 11, 2 | 2018-09-11 |
Methods and compositions for modulating PD1
Grant 10,046,028 - Gregory , et al. August 14, 2 | 2018-08-14 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20180223311 - Cost; Gregory J. ; et al. | 2018-08-09 |
Targeted Integration Into The Ppp1r12c Locus
App 20180201955 - DeKelver; Russell ; et al. | 2018-07-19 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20180148740 - Conway; Anthony ; et al. | 2018-05-31 |
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,970,028 - Cost , et al. May 15, 2 | 2018-05-15 |
Methods and compositions for treatment of a genetic condition
Grant 9,963,715 - Cost , et al. May 8, 2 | 2018-05-08 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20180119175 - Conway; Anthony ; et al. | 2018-05-03 |
Targeted integration into the PPP1R12C locus
Grant 9,914,940 - DeKelver , et al. March 13, 2 | 2018-03-13 |
Methods and compositions for treatment of a genetic condition
Grant 9,902,974 - Conway , et al. February 27, 2 | 2018-02-27 |
Methods and compositions for treatment of a genetic condition
Grant 9,873,894 - Conway , et al. January 23, 2 | 2018-01-23 |
Novel Dna-binding Proteins And Uses Thereof
App 20180010152 - Gregory; Philip D. ; et al. | 2018-01-11 |
Targeted integration into stem cells
Grant 9,834,787 - Gregory , et al. December 5, 2 | 2017-12-05 |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
Grant 9,833,479 - Conway , et al. December 5, 2 | 2017-12-05 |
Methods And Compositions For Targeted Cleavage And Recombination
App 20170326174 - Holmes; Michael C. ; et al. | 2017-11-16 |
Targeted Deletion Of Cellular Dna Sequences
App 20170298385 - Guschin; Dmitry ; et al. | 2017-10-19 |
Methods and compositions for targeted cleavage and recombination
Grant 9,782,437 - Holmes , et al. October 10, 2 | 2017-10-10 |
DNA-binding proteins and uses thereof
Grant 9,783,827 - Gregory , et al. October 10, 2 | 2017-10-10 |
Linear donor constructs for targeted integration
Grant 9,765,360 - DeKelver , et al. September 19, 2 | 2017-09-19 |
Methods and compostions for targeted genomic deletion
Grant 9,752,140 - Urnov , et al. September 5, 2 | 2017-09-05 |
Modulation Of Stem Cells Using Zinc Finger Proteins
App 20170224741 - Wolffe; Alan P. ; et al. | 2017-08-10 |
Gene Correction Of Scid-related Genes In Hematopoietic Stem And Progenitor Cells
App 20170189450 - Conway; Anthony ; et al. | 2017-07-06 |
Targeted deletion of cellular DNA sequences
Grant 9,695,442 - Guschin , et al. July 4, 2 | 2017-07-04 |
Methods and compositions for treatment of a genetic condition
Grant 9,650,648 - Cost , et al. May 16, 2 | 2017-05-16 |
Modulation of stem cells using zinc finger proteins
Grant 9,624,509 - Wolffe , et al. April 18, 2 | 2017-04-18 |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
Grant 9,616,090 - Conway , et al. April 11, 2 | 2017-04-11 |
Targeted Modification Of Malate Dehydrogenase
App 20170088825 - Shukla; Vipula ; et al. | 2017-03-30 |
Novel Dna-binding Proteins And Uses Thereof
App 20170016030 - Gregory; Philip D. ; et al. | 2017-01-19 |
Targeted modification of malate dehydrogenase
Grant 9,523,098 - Shukla , et al. December 20, 2 | 2016-12-20 |
Rapid in vivo identification of biologically active nucleases
Grant 9,506,120 - Doyon , et al. November 29, 2 | 2016-11-29 |
DNA-binding proteins and uses thereof
Grant 9,493,750 - Gregory , et al. November 15, 2 | 2016-11-15 |
Targeted Integration Into The Ppp1r12c Locus
App 20160289699 - DeKelver; Russell ; et al. | 2016-10-06 |
Modified DNA-binding proteins and uses thereof
Grant 9,458,205 - Gregory , et al. October 4, 2 | 2016-10-04 |
Linear Donor Constructs For Targeted Integration
App 20160237457 - DeKelver; Russell ; et al. | 2016-08-18 |
Methods And Compositions For Modulating Pd1
App 20160220634 - Gregory; Philip D. ; et al. | 2016-08-04 |
Methods and compositions for modulating PD1
Grant 9,402,879 - Gregory , et al. August 2, 2 | 2016-08-02 |
Linear donor constructs for targeted integration
Grant 9,376,685 - DeKelver , et al. June 28, 2 | 2016-06-28 |
Methods And Compostions For Targeted Genomic Deletion
App 20160177290 - Urnov; Fyodor ; et al. | 2016-06-23 |
Targeted Genomic Modification With Partially Single-stranded Donor Molecules
App 20160145644 - Cost; Gregory J. ; et al. | 2016-05-26 |
Optimized Non-canonical Zinc Finger Proteins
App 20160130314 - Cai; Qihua C. ; et al. | 2016-05-12 |
DNA-binding proteins and uses thereof
Grant 9,322,005 - Gregory , et al. April 26, 2 | 2016-04-26 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20160090607 - Conway; Anthony ; et al. | 2016-03-31 |
Methods and compositions for targeted cleavage and recombination
Grant 9,289,451 - Urnov , et al. March 22, 2 | 2016-03-22 |
Genome Editing In Rats Using Zinc-finger Nucleases
App 20160068865 - Cui; Xiaoxia ; et al. | 2016-03-10 |
Targeted integration into the PPP1R12C locus
Grant 9,267,154 - DeKelver , et al. February 23, 2 | 2016-02-23 |
Targeted integration and expression on exogenous nucleic acid sequences
Grant 9,260,726 - Gregory , et al. February 16, 2 | 2016-02-16 |
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,255,259 - Cost , et al. February 9, 2 | 2016-02-09 |
Gene Correction Of Scid-related Genes In Hematopoietic Stem And Progenitor Cells
App 20160030477 - Conway; Anthony ; et al. | 2016-02-04 |
Methods and compositions for targeted genomic deletion
Grant 9,249,428 - Urnov , et al. February 2, 2 | 2016-02-02 |
Methods and compositions for modification of the HPRT locus
Grant 9,222,105 - Cost , et al. December 29, 2 | 2015-12-29 |
Method of deleting an IgM gene in an isolated rat cell
Grant 9,206,404 - Cui , et al. December 8, 2 | 2015-12-08 |
Optimized non-canonical zinc finger proteins
Grant 9,187,758 - Cai , et al. November 17, 2 | 2015-11-17 |
Methods And Compositions For Regulating Hiv Infection
App 20150267223 - Holmes; Michael C. ; et al. | 2015-09-24 |
Methods And Compositions For Modification Of A Hla Locus
App 20150252094 - Collingwood; Trevor ; et al. | 2015-09-10 |
Linear Donor Constructs For Targeted Integration
App 20150225727 - DeKelver; Russell ; et al. | 2015-08-13 |
Linear donor constructs for targeted integration
Grant 9,045,763 - DeKelver , et al. June 2, 2 | 2015-06-02 |
Nuclease-mediated Regulation Of Gene Expression
App 20150132269 - Orkin; Stuart H. ; et al. | 2015-05-14 |
Targeted genomic modification with partially single-stranded donor molecules
Grant 9,005,973 - Cost , et al. April 14, 2 | 2015-04-14 |
Engineered Zinc Finger Proteins Targeting 5-enolpyruvyl Shikimate-3-phosphate Synthase Genes
App 20150064790 - Gupta; Manju ; et al. | 2015-03-05 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20150056705 - Conway; Anthony ; et al. | 2015-02-26 |
Methods and compositions for modification of a HLA locus
Grant 8,945,868 - Collingwood , et al. February 3, 2 | 2015-02-03 |
Methods And Compositions For Targeted Genomic Deletion
App 20150031090 - Urnov; Fyodor ; et al. | 2015-01-29 |
Optimized non-canonical zinc finger proteins
Grant 8,921,112 - Cai , et al. December 30, 2 | 2014-12-30 |
Methods And Compositions For Targeted Cleavage And Recombination
App 20140369980 - Holmes; Michael C. ; et al. | 2014-12-18 |
DNA-binding proteins and uses thereof
Grant 8,912,138 - Gregory , et al. December 16, 2 | 2014-12-16 |
Targeted Integration Into The Ppp1r12c Locus
App 20140349394 - DeKelver; Russell ; et al. | 2014-11-27 |
Methods and compositions for modification of the HPRT locus
Grant 8,895,264 - Cost , et al. November 25, 2 | 2014-11-25 |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
Grant 8,889,390 - Gupta , et al. November 18, 2 | 2014-11-18 |
Targeted integration into the PPP1R12C locus
Grant 8,822,221 - DeKelver , et al. September 2, 2 | 2014-09-02 |
Modulation Of Stem Cells Using Zinc Finger Proteins
App 20140234970 - Wolffe; Alan P. ; et al. | 2014-08-21 |
Modulation of stem cells using zinc finger proteins
Grant 8,735,153 - Wolffe , et al. May 27, 2 | 2014-05-27 |
Novel Dna-binding Proteins And Uses Thereof
App 20140134741 - Gregory; Philip D. ; et al. | 2014-05-15 |
Novel Dna-binding Proteins And Uses Thereof
App 20140134740 - Gregory; Philip D. ; et al. | 2014-05-15 |
Novel Dna-binding Proteins And Uses Thereof
App 20140134723 - Gregory; Philip D. ; et al. | 2014-05-15 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20140093913 - Cost; Gregory J. ; et al. | 2014-04-03 |
Methods And Compositions For Targeted Cleavage And Recombination
App 20140086885 - Urnov; Fyodor ; et al. | 2014-03-27 |
Methods And Compositions For Treatment Of A Genetic Condition
App 20140080216 - Cost; Gregory J. ; et al. | 2014-03-20 |
Targeted Deletion Of Cellular Dna Sequences
App 20140065667 - Guschin; Dmitry ; et al. | 2014-03-06 |
Methods And Compositions For Modulating Pd1
App 20140030240 - Gregory; Philip D. ; et al. | 2014-01-30 |
Methods And Compositions For Nuclease-mediated Targeted Integration Of Transgenes
App 20130326645 - Cost; Gregory J. ; et al. | 2013-12-05 |
Targeted Modification Of Malate Dehydrogenase
App 20130326725 - Shukla; Vipula ; et al. | 2013-12-05 |
DNA-binding proteins and uses thereof
Grant 8,586,526 - Gregory , et al. November 19, 2 | 2013-11-19 |
Methods and compositions for modulating PD1
Grant 8,563,314 - Gregory , et al. October 22, 2 | 2013-10-22 |
Taregted Integration And Expression Of Exogenous Nucleic Acid Sequences
App 20130244332 - Gregory; Philip D. ; et al. | 2013-09-19 |
Methods and compositions for targeted cleavage and recombination
Grant 8,524,500 - Urnov , et al. September 3, 2 | 2013-09-03 |
Methods And Compostitions For Gene Editing Of A Pathogen
App 20130216579 - Fidock; David ; et al. | 2013-08-22 |
Organisms Homozygous For Targeted Modification
App 20130198878 - Doyon; Yannick ; et al. | 2013-08-01 |
Modified Dna-binding Proteins And Uses Thereof
App 20130196373 - Gregory; Philip D. ; et al. | 2013-08-01 |
Methods And Compositions For Regulating Hiv Infection
App 20130171732 - Holmes; Michael C. ; et al. | 2013-07-04 |
Engineered Zinc Finger Proteins Targeting 5-enolpyruvyl Shikimate-3-phosphate Synthase Genes
App 20130145503 - Gupta; Manju ; et al. | 2013-06-06 |
Methods And Compositions For Modification Of The Hprt Locus
App 20130137104 - Cost; Gregory J. ; et al. | 2013-05-30 |
Methods And Compositions For Modification Of The Hprt Locus
App 20130122591 - Cost; Gregory J. ; et al. | 2013-05-16 |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
Grant 8,399,218 - Gupta , et al. March 19, 2 | 2013-03-19 |
Targeted integration into the Zp15 locus
Grant 8,329,986 - Butler , et al. December 11, 2 | 2012-12-11 |
Methods And Compositions For Targeted Genomic Deletion
App 20120196370 - URNOV; Fyodor ; et al. | 2012-08-02 |
Targeted Integration Into The Ppp1r12c Locus
App 20120142055 - DeKelver; Russell ; et al. | 2012-06-07 |
Methods And Compositions For Analysis Of Regulatory Sequences
App 20120088677 - URNOV; Fyodor ; et al. | 2012-04-12 |
Methods And Compositions For Modification Of A Hla Locus
App 20120060230 - Collingwood; Trevor ; et al. | 2012-03-08 |
Targeted integration into the PPP1R12C locus
Grant 8,110,379 - DeKelver , et al. February 7, 2 | 2012-02-07 |
Novel DNA-binding proteins and uses thereof
App 20110301073 - Gregory; Philip D. ; et al. | 2011-12-08 |
Targeted modification of chromatin structure
Grant 8,071,370 - Wolffe , et al. December 6, 2 | 2011-12-06 |
Targeted genomic modification with partially single-stranded donor molecules
App 20110287545 - Cost; Gregory J. ; et al. | 2011-11-24 |
Linear donor constructs for targeted integration
App 20110281361 - DeKelver; Russell ; et al. | 2011-11-17 |
Targeted genomic modification with partially single-stranded donor molecules
App 20110207221 - Cost; Gregory J. ; et al. | 2011-08-25 |
Targeted genomic alteration
App 20110189775 - Ainley; William M. ; et al. | 2011-08-04 |
Methods and compositions for modulating PD1
App 20110136895 - Gregory; Philip D. ; et al. | 2011-06-09 |
Libraries of regulatory sequences, methods of making and using same
Grant 7,923,542 - Wolffe , et al. April 12, 2 | 2011-04-12 |
Methods and compositions for targeted cleavage and recombination
Grant 7,888,121 - Urnov , et al. February 15, 2 | 2011-02-15 |
Methods and compositions for targeted cleavage and recombination
App 20110030076 - Urnov; Fyodor ; et al. | 2011-02-03 |
Targeted integration into stem cells
App 20110027235 - Gregory; Philip D. ; et al. | 2011-02-03 |
Targeted modification of chromatin structure
App 20100323424 - Wolffe; Alan P. ; et al. | 2010-12-23 |
Targeted modification of chromatin structure
Grant 7,785,792 - Wolffe , et al. August 31, 2 | 2010-08-31 |
Genome editing in rats using zinc-finger nucleases
App 20100218264 - Cui; Xiaoxia ; et al. | 2010-08-26 |
Targeted integration into the Zp15 locus
App 20100199389 - Butler; Holly J. ; et al. | 2010-08-05 |
Linear donor constructs for targeted integration
App 20090263900 - DeKelver; Russell ; et al. | 2009-10-22 |
Genomic editing in zebrafish using zinc finger nucleases
App 20090203140 - AMACHER; SHARON ; et al. | 2009-08-13 |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
App 20090205083 - Gupta; Manju ; et al. | 2009-08-13 |
Rapid in vivo identification of biologically active nucleases
App 20090111119 - Doyon; Yannick ; et al. | 2009-04-30 |
Optimized non-canonical zinc finger proteins
App 20090111188 - Cai; Qihua C. ; et al. | 2009-04-30 |
Targeted integration into the PPP1R12C locus
App 20080299580 - DeKelver; Russell ; et al. | 2008-12-04 |
Optimized non-canonical zinc finger proteins
App 20080182332 - Cai; Qihua C. ; et al. | 2008-07-31 |
Functional genomics using zinc finger proteins
Grant 7,235,354 - Case , et al. June 26, 2 | 2007-06-26 |
Targeted integration and expression of exogenous nucleic acid sequences
App 20070134796 - Holmes; Michael C. ; et al. | 2007-06-14 |
Modulation of endogenous gene expression in cells
Grant 7,220,719 - Case , et al. May 22, 2 | 2007-05-22 |
Databases of regulatory sequences; methods of making and using same
Grant 7,217,509 - Wolffe , et al. May 15, 2 | 2007-05-15 |
Modulation of stem cells using zinc finger proteins
App 20060251642 - Wolffe; Alan P. ; et al. | 2006-11-09 |
Screening methods based on isolating a collection of polynucleotides corresponding to accessible regions of chromatin
Grant 7,097,978 - Wolffe , et al. August 29, 2 | 2006-08-29 |
Methods and compositions for analysis of regulatory sequences
App 20060166206 - Urnov; Fyodor ; et al. | 2006-07-27 |
Modulation of endogenous gene expression in cells
Grant 6,933,113 - Case , et al. August 23, 2 | 2005-08-23 |
Modulation of gene expression using localization domains
Grant 6,919,204 - Wolffe , et al. July 19, 2 | 2005-07-19 |
Modulation of gene expression using localization domains
App 20050130267 - Wolffe, Alan P. ; et al. | 2005-06-16 |
Methods and compositions for targeted cleavage and recombination
App 20050064474 - Urnov, Fyodor ; et al. | 2005-03-24 |
Methods for genome annotation
App 20050032108 - Case, Casey C. ; et al. | 2005-02-10 |
Functional genomics using zinc finger proteins
App 20040203064 - Case, Casey C. ; et al. | 2004-10-14 |
Modulation of endogenous gene expression in cells
App 20040204345 - Case, Casey C. ; et al. | 2004-10-14 |
Gene identification
Grant 6,780,590 - Case , et al. August 24, 2 | 2004-08-24 |
Functional genomics using zinc finger proteins
Grant 6,777,185 - Case , et al. August 17, 2 | 2004-08-17 |
Pharmacogenomics and idenitfication of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions
App 20030190664 - Wolffe, Alan ; et al. | 2003-10-09 |
Pharmacogenomics and identification of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions
Grant 6,610,489 - Wolffe , et al. August 26, 2 | 2003-08-26 |
Databases of regulatory sequences; methods of making and using same
App 20030129603 - Wolffe, Alan P. ; et al. | 2003-07-10 |
Modulation of gene expression using localization domains
App 20030082552 - Wolffe, Alan P. ; et al. | 2003-05-01 |
Methods for designing exogenous regulatory molecules
Grant 6,511,808 - Wolffe , et al. January 28, 2 | 2003-01-28 |
Gene identification
App 20020164575 - Case, Casey C. ; et al. | 2002-11-07 |
Modulation of endogenous gene expression in cells
App 20020160940 - Case, Casey C. ; et al. | 2002-10-31 |
Pharmacogenomics and identification of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions
App 20020127559 - Wolffe, Alan ; et al. | 2002-09-12 |
Gene identification
App 20020094529 - Case, Casey C. ; et al. | 2002-07-18 |
Databases of regulatory sequences; methods of making and using same
App 20020081603 - Wolffe, Alan ; et al. | 2002-06-27 |
Methods for designing exogenous regulatory molecules
App 20020076711 - Wolffe, Alan ; et al. | 2002-06-20 |
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