Patent | Date |
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3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same Grant 4,719,231 - Umezawa , et al. January 12, 1 | 1988-01-12 |
4'-demethyl-4-epipodophyllotoxin derivative Grant 4,716,221 - Umezawa , et al. December 29, 1 | 1987-12-29 |
Medical composition for injection containing a spergualin as active ingredient and process for preparing the same Grant 4,710,517 - Umezawa , et al. December 1, 1 | 1987-12-01 |
Novel physiologically active substance MH435 Grant 4,686,308 - Umezawa , et al. August 11, 1 | 1987-08-11 |
11-O-methylspergualin Grant 4,658,058 - Umezawa , et al. April 14, 1 | 1987-04-14 |
Physiologically active substance, arphamenine and production thereof Grant 4,595,698 - Umezawa , et al. June 17, 1 | 1986-06-17 |
1-N-(.omega.-Amino-.alpha.-hydroxyalkanoyl-2',3'-dideoxykanamycin A and pharmaceutical composition containing same Grant 4,547,492 - Umezawa , et al. October 15, 1 | 1985-10-15 |
Derivatives of 4'-demethyl-4-epipodophyllotoxin Grant 4,547,567 - Umezawa , et al. October 15, 1 | 1985-10-15 |
Water-insoluble biospecific absorbent containing argininal derivative Grant 4,525,465 - Someno , et al. June 25, 1 | 1985-06-25 |
Anthracycline antibiotics Grant 4,474,945 - Yoshimoto , et al. October 2, 1 | 1984-10-02 |
Novel carcinostatic substance and process for synthesis thereof Grant 4,430,346 - Umezawa , et al. February 7, 1 | 1984-02-07 |
Istamycins and streptomyces culture for the production thereof Grant 4,380,581 - Umezawa , et al. April 19, 1 | 1983-04-19 |
Bestatin-related compounds as immunopotentiator Grant 4,370,318 - Umezawa , et al. January 25, 1 | 1983-01-25 |
Ebelactones and production thereof Grant 4,358,602 - Umezawa , et al. November 9, 1 | 1982-11-09 |
Cleomycins and process for producing same Grant 4,326,054 - Umezawa , et al. April 20, 1 | 1982-04-20 |
Physiologically active tetrapeptides Grant 4,318,847 - Umezawa , et al. March 9, 1 | 1982-03-09 |
Antitumor anthracycline antibiotics Grant 4,303,785 - Umezawa , et al. December 1, 1 | 1981-12-01 |
3',4'-Dideoxykanamycin A and 1-N-(S)-.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives thereof Grant 4,298,727 - Umezawa , et al. November 3, 1 | 1981-11-03 |
Production of a selectively protected N-acylated derivative of an aminoglycosidic antibiotic Grant 4,297,485 - Umezawa , et al. October 27, 1 | 1981-10-27 |
Istamycins and production thereof Grant 4,296,106 - Umezawa , et al. October 20, 1 | 1981-10-20 |
Cultivating streptomyces to produce an esterase inhibitor Grant 4,242,453 - Umezawa , et al. December 30, 1 | 1980-12-30 |
Pharmacological compound with immunopotentiating activity and production and uses thereof Grant 4,238,507 - Umezawa , et al. December 9, 1 | 1980-12-09 |
Process for producing new antitumor anthracycline antibiotics Grant 4,209,588 - Umezawa , et al. June 24, 1 | 1980-06-24 |
Novel macrolactone derivatives and process of producing them Grant 4,196,280 - Umezawa , et al. April 1, 1 | 1980-04-01 |
3',4'-Episulfido kanamycin B compounds Grant 4,195,170 - Umezawa , et al. March 25, 1 | 1980-03-25 |
3-[(S)-1'-Phenylethylamino]propylaminobleomycin, non-toxic salt thereof, and method for producing same Grant 4,195,018 - Takita , et al. March 25, 1 | 1980-03-25 |
Physiologically active substance esterastin Grant 4,189,438 - Umezawa , et al. February 19, 1 | 1980-02-19 |
Bestatin Grant 4,189,604 - Umezawa , et al. February 19, 1 | 1980-02-19 |
Peptides and acid addition salts thereof Grant 4,185,156 - Umezawa , et al. January 22, 1 | 1980-01-22 |
Derivatives of kanamycin A Grant 4,170,642 - Umezawa , et al. October 9, 1 | 1979-10-09 |
Isocoformycin and a process for the production thereof Grant 4,163,839 - Umezawa , et al. August 7, 1 | 1979-08-07 |
Process for the synthesis of 3',4'-dideoxykanamycin B and products Grant 4,156,078 - Umezawa , et al. May 22, 1 | 1979-05-22 |
Anthracycline glycosides Grant 4,127,714 - Umezawa , et al. November 28, 1 | 1978-11-28 |
Novel process for the preparation of 1-N-(alpha-substituted-omega-aminoacyl)-3'-deoxyribostamycin Grant 4,125,706 - Umezawa , et al. November 14, 1 | 1978-11-14 |
Method for production of kanamycin C and its derivatives Grant 4,120,955 - Umezawa , et al. October 17, 1 | 1978-10-17 |
1-N-[(S)-.alpha.-hydroxy-.omega.-aminoacyl] derivatives of 3',4'-dideoxykanamycin B and 3'-deoxykanamycin B antibiotics Grant 4,107,424 - Umezawa , et al. August 15, 1 | 1978-08-15 |
Neothramycin antibiotics Grant 4,105,658 - Umezawa , et al. August 8, 1 | 1978-08-08 |
Process for producing stable macromomycin powder Grant 4,102,999 - Umezawa , et al. July 25, 1 | 1978-07-25 |
Pepstatin floating minicapsules Grant 4,101,650 - Umezawa July 18, 1 | 1978-07-18 |
N-methanesulfonic acid derivatives of 3',4'-dideoxykanamycin B Grant 4,091,202 - Umezawa , et al. May 23, 1 | 1978-05-23 |
Treatment of elevated histamine and uric acid levels Grant 4,091,097 - Umezawa , et al. May 23, 1 | 1978-05-23 |
3'-Epi-4'deoxykanamycin B Grant 4,078,138 - Akita , et al. March 7, 1 | 1978-03-07 |
Processes for production of a 1-N-(.alpha.-hydroxy-.PHI.-amino alkanoyl)-3-deoxy-5-O-pentafuranosyl neamine and new compounds produced by the same processes Grant 4,065,616 - Umezawa , et al. December 27, 1 | 1977-12-27 |
Processes for producing physiologically active peptide and its N-acyl derivatives Grant 4,055,468 - Umezawa , et al. October 25, 1 | 1977-10-25 |
Pharmaceutical method for the therapy of immune diseases Grant 4,032,635 - Umezawa , et al. June 28, 1 | 1977-06-28 |
Treatment of elevated histamine and uric acid levels Grant 4,024,253 - Umezawa , et al. May 17, 1 | 1977-05-17 |
1-N-[(S)-.alpha.-hydroxy-.omega.-aminoacyl] Grant 4,001,208 - Umezawa , et al. January 4, 1 | 1977-01-04 |
Process for the production of monopropionyl-josamycin-2 Grant 4,001,399 - Osono , et al. January 4, 1 | 1977-01-04 |
Antibiotics aclacinomycins A and B Grant 3,988,315 - Umezawa , et al. October 26, 1 | 1976-10-26 |
Microbial production of certain isoflavones Grant 3,974,184 - Umezawa , et al. August 10, 1 | 1976-08-10 |
Treatment of elevated histamine and uric acid levels Grant 3,973,038 - Umezawa , et al. August 3, 1 | 1976-08-03 |
New compound 6'-deoxy-'-substituted or unsubstituted amino-lividomycins and the production thereof Grant 3,956,274 - Umezawa , et al. May 11, 1 | 1976-05-11 |
3'-Deoxy derivatives of neamine and its related aminoglycosidic antibiotics, and the production thereof Grant 3,929,762 - Umezawa , et al. December 30, 1 | 1975-12-30 |
Process for the production of an 1-n-(s)-alpha- substituted-w-aminoacyl) derivative of neamine, 3', 4'-dideoxyneamine, ribostamycin or 3',4'-dideoxyribostamycin Grant 3,925,354 - Umezawa , et al. December 9, 1 | 1975-12-09 |
Preparation of 3-4 dideoxykanamycin B active against resistant bacteria Grant RE28,647 - Umezawa , et al. December 9, 1 | 1975-12-09 |
4-0-(6-Alkylamino-6-deoxy-alpha-D-hexopyranosyl)-deoxystreptamine derivatives and the production thereof Grant 3,925,353 - Umezawa , et al. December 9, 1 | 1975-12-09 |
Process for the production of new pepstatins having anti-pepsin activity Grant 3,869,347 - Umezawa , et al. March 4, 1 | 1975-03-04 |
Process for the synthesis of leupeptins and their analogues Grant 3,867,364 - Umezawa , et al. February 18, 1 | 1975-02-18 |