Tsien; Roger Y.

Patent Applications and Registrations

Patent applications and USPTO patent grants for Tsien; Roger Y..The latest application filed is for "optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic delivery".

Company Profile

5.119.85

Tsien; Roger Y. - Eugene OR
Tsien; Roger Y. - La Jolla CA
Tsien; Roger Y. - LaJolla CA
Tsien; Roger Y. - Berkeley CA

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.

Patent Activity

Patent	Date
Compositions and methods for imaging cell populations Grant 11,406,721 - Tsien , et al. August 9, 2	2022-08-09
Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic Grant 11,299,515 - Nguyen , et al. April 12, 2	2022-04-12
Fluorescent probes for monitoring voltage by photo-induced electron transfer Grant 11,187,660 - Miller , et al. November 30, 2	2021-11-30
Optimized Peptides For Targeting Human Nerves And Their Use In Image Guided Surgery, Diagnostics And Therapeutic Delivery App 20210363186 - Nguyen; Quyen T. ; et al.	2021-11-25
Compositions And Methods For Imaging Cell Populations App 20210205479 - Tsien; Roger Y. ; et al.	2021-07-08
Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic delivery Grant 11,021,517 - Nguyen , et al. June 1, 2	2021-06-01
Optimized Peptides for Targeting Human Nerves and Their Use in Image Guided Surgery, Diagnostics and Therapeutic Delivery App 20210087229 - Nguyen; Quyen T. ; et al.	2021-03-25
Optimized Peptides for Targeting Human Nerves and Their Use in Image Guided Surgery, Diagnostics and Therapeutic Delivery App 20200239522 - Nguyen; Quyen T. ; et al.	2020-07-30
Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof Grant 10,596,259 - Savariar , et al.	2020-03-24
Personalized protease assay to measure protease activity in neoplasms Grant 10,385,380 - Whitney , et al. A	2019-08-20
Imaging System And Method For Fluorescence Guided Surgery App 20190175021 - Steinbach; Paul ; et al.	2019-06-13
Imaging system and method for fluorescence guided surgery Grant 10,231,626 - Steinbach , et al.	2019-03-19
Pretargeted activatable cell penetrating peptide with intracellularly releasable prodrug Grant 10,029,017 - Savariar , et al. July 24, 2	2018-07-24
Tumor Radiosensitization With Antibody Conjugates App 20180140703 - Advani; Sunil J. ; et al.	2018-05-24
Fluorescent Probes For Monitoring Voltage By Photo-induced Electron Transfer App 20170315059 - Miller; Evan Walker ; et al.	2017-11-02
Activatable cell penetrating peptides with quenched fluorophores Grant 9,695,251 - Tsien , et al. July 4, 2	2017-07-04
Fluorescent probes for monitoring voltage by photo-induced electron transfer Grant 9,651,494 - Miller , et al. May 16, 2	2017-05-16
Tumor Radiosensitization With Monomethyl Auristatin E (mmae) And Derivatives Thereof App 20170080088 - Savariar; Elamprakash N. ; et al.	2017-03-23
Personalized Protease Assay To Measure Protease Activity In Neoplasms App 20160160263 - Whitney; Mike ; et al.	2016-06-09
Proteins that efficiently generate singlet oxygen Grant 9,279,769 - Shu , et al. March 8, 2	2016-03-08
Pretargeted Activatable Cell Penetrating Peptide With Intracellularly Releasable Prodrug App 20150359902 - Savariar; Elamprakash N. ; et al.	2015-12-17
Fusion proteins and polynucleotide constructs to measure protein turn-over Grant 8,993,256 - Lin , et al. March 31, 2	2015-03-31
Methods for engineering polypeptide variants via somatic hypermutation and polypeptide made thereby Grant 8,932,859 - Tsien , et al. January 13, 2	2015-01-13
Imaging System And Method For Fluorescence Guided Surgery App 20140276008 - Steinbach; Paul ; et al.	2014-09-18
Engineered red-shifted channelrhodopsin variants Grant 8,759,492 - Lin , et al. June 24, 2	2014-06-24
Fluorescent Probes For Monitoring Voltage By Photo-induced Electron Transfer App 20140093907 - Miller; Evan Walker ; et al.	2014-04-03
Peptides and aptamers for targeting of neuron or nerves Grant 8,685,372 - Tsien , et al. April 1, 2	2014-04-01
Method for determining the presence of an enzyme in a sample Grant 8,679,742 - Tsien , et al. March 25, 2	2014-03-25
Chimeric phosphorylation indicator Grant 8,669,074 - Violin , et al. March 11, 2	2014-03-11
Peptides whose uptake by cells is controllable Grant 8,642,561 - Jiang , et al. February 4, 2	2014-02-04
Proteins That Efficiently Generate Singlet Oxygen App 20130330718 - Shu; Xiaokun ; et al.	2013-12-12
Activatable Cell Penetrating Peptides With Quenched Fluorophores App 20130078188 - Tsien; Roger Y. ; et al.	2013-03-28
Engineered Red-shifted Channelrhodopsin Variants App 20130066402 - Lin; John Yu-luen ; et al.	2013-03-14
Photon Reducing Agents For Fluorescence Assays App 20130004960 - KNAPP; Tom ; et al.	2013-01-03
Peptides Whose Uptake By Cells Is Controllable App 20120251445 - Jiang; Tao ; et al.	2012-10-04
Peptides And Aptamers For Targeting Of Neuron Or Nerves App 20120148499 - Tsien; Roger Y. ; et al.	2012-06-14
Peptides whose uptake by cells is controllable Grant 8,110,554 - Jiang , et al. February 7, 2	2012-02-07
Peptides Whose Uptake By Cells Is Controllable App 20120014873 - Jiang; Tao ; et al.	2012-01-19
Substrates for beta-lactamase and uses thereof Grant 8,071,761 - Tsien , et al. December 6, 2	2011-12-06
Synthetic molecules that specifically react with target sequences Grant 8,071,789 - Tsien , et al. December 6, 2	2011-12-06
Fluorescent protein sensors for detection of analytes Grant 7,993,879 - Tsien , et al. August 9, 2	2011-08-09
Peptides Whose Uptake By Cells Is Controllable App 20110172139 - Jiang; Tao ; et al.	2011-07-14
Photon Reducing Agents For Fluorescence Assays App 20110076711 - KNAPP; Tom ; et al.	2011-03-31
Monomeric and dimeric fluorescent protein variants and methods for making same Grant 7,906,636 - Tsien , et al. March 15, 2	2011-03-15
Multi-well platforms, caddies, lids and combinations thereof Grant 7,854,898 - Pham , et al. December 21, 2	2010-12-21
Synthetic Molecules That Specifically React With Target Sequences App 20100317097 - Tsien; Roger Y. ; et al.	2010-12-16
Tandem Fluorescent Protein Constructs App 20100233726 - Tsien; Roger Y. ; et al.	2010-09-16
Monomeric And Dimeric Fluorescent Protein Variants And Methods For Making Same App 20100227400 - Campbell; Robert E. ; et al.	2010-09-09
Detection of transmembrane potentials by optical methods Grant 7,687,282 - Tsien , et al. March 30, 2	2010-03-30
Monomeric and dimeric fluorescent protein variants and methods for making same Grant 7,687,614 - Campbell , et al. March 30, 2	2010-03-30
Drug Controlled Molecular Tags App 20100041092 - Lin; Michael Z. ; et al.	2010-02-18
Fluorescent Proteins With Increased Photostability App 20090203035 - Shaner; Nathan C. ; et al.	2009-08-13
Long wavelength engineered fluorescent proteins Grant 7,560,287 - Tsien , et al. July 14, 2	2009-07-14
Photon Reducing Agents For Fluorescence Assays App 20090162926 - Knapp; Tom ; et al.	2009-06-25
Multi-Well Platforms, Caddies, Lids and Combinations Thereof App 20090148350 - Pham; Andrew A. ; et al.	2009-06-11
Synthetic molecules that specifically react with target sequences Grant 7,524,972 - Tsien , et al. April 28, 2	2009-04-28
Multi-well platforms, caddies, lids and combinations thereof Grant 7,459,130 - Pham , et al. December 2, 2	2008-12-02
Methods For Engineering Polypeptide Variants Via Somatic Hypermutation And Polypeptide Made Thereby App 20080293068 - Tsien; Roger Y. ; et al.	2008-11-27
Peptides whose uptake by cells is controllable Grant 7,431,915 - Jiang , et al. October 7, 2	2008-10-07
Fluorogenic substrates for BETA-lactamase gene expression Grant 7,427,680 - Tsien , et al. September 23, 2	2008-09-23
Beta-lactamase substrates having phenolic ethers Grant 7,396,926 - Tsien , et al. July 8, 2	2008-07-08
Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same Grant 7,393,923 - Tsien , et al. July 1, 2	2008-07-01
Non-oligomerizing tandem fluorescent proteins Grant 7,332,598 - Tsien , et al. February 19, 2	2008-02-19
Fluorescent protein variants and methods for making same Grant 7,329,735 - Tsien , et al. February 12, 2	2008-02-12
Substrates for beta-lactamase and uses thereof App 20070184513 - Tsien; Roger Y. ; et al.	2007-08-09
Synthetic Molecules That Specifically React With Target Sequences App 20070185074 - Tsien; Roger Y. ; et al.	2007-08-09
Detector and screening device for ion channels App 20070139639 - Tsien; Roger Y. ; et al.	2007-06-21
Detection of transmembrane potentials by optical methods Grant 7,173,130 - Tsien , et al. February 6, 2	2007-02-06
Detection of transmembrane potentials by optical methods App 20070026384 - Tsien; Roger Y. ; et al.	2007-02-01
Novel fluorogenic substrates for beta-lactamase gene expression App 20070020715 - Tsien; Roger Y. ; et al.	2007-01-25
Low fluorescence assay platforms and related methods for drug discovery App 20070009883 - Coassin; Peter J. ; et al.	2007-01-11
Fluorescein-based metal sensors, and methods of making and using the same Grant 7,160,732 - Lippard , et al. January 9, 2	2007-01-09
Substrates for .beta.-lactamase and uses thereof Grant 7,157,575 - Tsien , et al. January 2, 2	2007-01-02
Monomeric and dimeric fluorescent protein variants and methods for making same Grant 7,157,566 - Tsien , et al. January 2, 2	2007-01-02
Detector and screening device for ion channels Grant 7,142,290 - Tsien , et al. November 28, 2	2006-11-28
Synthetic molecules that specifically react with target sequences Grant 7,138,503 - Tsien , et al. November 21, 2	2006-11-21
Detection of transmembrane potentials by optical methods Grant 7,118,899 - Tsien , et al. October 10, 2	2006-10-10
Detection of transmembrane potentials by optical methods Grant 7,115,401 - Tsien , et al. October 3, 2	2006-10-03
Fluorescent protein variants and methods for making same App 20060194282 - Tsien; Roger Y. ; et al.	2006-08-31
Detection of transmembrane potentials by optical methods Grant 7,087,416 - Tsien , et al. August 8, 2	2006-08-08
Detector and screening device for ion channels App 20060139624 - Tsien; Roger Y. ; et al.	2006-06-29
Photon reducing agents for fluorescence assays Grant 7,067,324 - Knapp , et al. June 27, 2	2006-06-27
Circularly permuted fluorescent protein indicators Grant 7,060,793 - Tsien , et al. June 13, 2	2006-06-13
Fluorescent protein sensors for detection of analytes Grant 7,060,869 - Tsien , et al. June 13, 2	2006-06-13
Fluorescent protein sensors for detection of analytes App 20060112440 - Tsien; Roger Y. ; et al.	2006-05-25
Methods for engineering polypeptide variants via somatic hypermutation and polypeptides made thereby App 20060099679 - Tsien; Roger Y. ; et al.	2006-05-11
Synthetic molecules for labeling histidine-rich proteins Grant 7,041,821 - Tsien , et al. May 9, 2	2006-05-09
Non-oligomerizing fluorescent proteins Grant 7,022,826 - Tsien , et al. April 4, 2	2006-04-04
Fluorescent protein variants and methods for making same Grant 7,005,511 - Tsien , et al. February 28, 2	2006-02-28
Peptides whose uptake by cells is controllable App 20060041105 - Jiang; Tao ; et al.	2006-02-23
Detector and screening device for ion channels Grant 7,002,671 - Tsien , et al. February 21, 2	2006-02-21
Monomeric and dimeric fluorescent protein variants and methods for making same App 20060003420 - Tsien; Roger Y. ; et al.	2006-01-05
Fluorescent Protein Variants And Methods For Making Same App 20050244921 - Tsien, Roger Y. ; et al.	2005-11-03
Multi-well platforms, caddies, lids and combinations thereof App 20050214174 - Pham, Andrew A. ; et al.	2005-09-29
Monomeric and dimeric fluorescent protein variants and methods for making same App 20050196768 - Campbell, Robert E. ; et al.	2005-09-08
Synthetic molecules for labeling histidine-rich proteins Grant 6,933,384 - Tsien , et al. August 23, 2	2005-08-23
Beta-lactamase substrates having phenolic ethers App 20050181469 - Tsien, Roger Y. ; et al.	2005-08-18
Photon reducing agents for fluorescence assays App 20050136469 - Knapp, Tom ; et al.	2005-06-23
Synthetic molecules that specifically react with target sequences App 20050131217 - Tsien, Roger Y. ; et al.	2005-06-16
Novel fluorogenic substrates for beta-lactamase gene expression App 20050118669 - Tsien, Roger Y. ; et al.	2005-06-02
Emission ratiometric indicators of phosphorylation Grant 6,900,304 - Tsien , et al. May 31, 2	2005-05-31
Peptides whose uptake by cells is controllable App 20050107583 - Jiang, Tao ; et al.	2005-05-19
Long wavelength engineered fluorescent proteins App 20050079525 - Tsien, Roger Y. ; et al.	2005-04-14
Multi-well platforms, caddies, lids and combinations thereof Grant 6,861,035 - Pham , et al. March 1, 2	2005-03-01
Non-oligomerizing tandem fluorescent proteins Grant 6,852,849 - Tsien , et al. February 8, 2	2005-02-08
Emission ratiometric indicators of phosphorylation by C-kinase App 20050026234 - Violin, Jonathan D. ; et al.	2005-02-03
Non-oligomerizing tandem fluorescent proteins App 20040259165 - Tsien, Roger Y. ; et al.	2004-12-23
Synthetic molecules for labeling histidine-rich proteins App 20040241749 - Tsien, Roger Y. ; et al.	2004-12-02
Low fluorescence assay platforms and related methods for drug discovery App 20040202582 - Coassin, Peter J. ; et al.	2004-10-14
Tandem fluorescent protein constructs Grant 6,803,188 - Tsien , et al. October 12, 2	2004-10-12
Modified green fluorescent proteins Grant 6,800,733 - Tsien , et al. October 5, 2	2004-10-05
Long wavelength engineered fluorescent proteins Grant 6,780,975 - Tsien , et al. August 24, 2	2004-08-24
Synthetic molecules for labeling histidine-rich proteins App 20040143122 - Tsien, Roger Y. ; et al.	2004-07-22
Low fluorescence assay platforms and related methods for drug discovery Grant 6,730,520 - Coassin , et al. May 4, 2	2004-05-04
Detector and screening device for ion channels App 20040051863 - Tsien, Roger Y. ; et al.	2004-03-18
Circularly permuted fluorescent protein indicators Grant 6,699,687 - Tsien , et al. March 2, 2	2004-03-02
Synthetic molecules that specifically react with target sequences Grant 6,686,458 - Tsien , et al. February 3, 2	2004-02-03
Detection of transmembrane potentials by optical methods App 20040002123 - Tsien, Roger Y. ; et al.	2004-01-01
Fluorescent protein sensors for measuring the pH of a biological sample App 20030212265 - Tsien, Roger Y. ; et al.	2003-11-13
Detection of transmembrane potentials by optical methods App 20030207248 - Tsien, Roger Y. ; et al.	2003-11-06
Emission ratiometric indicators of phosphorylation App 20030186229 - Tsien, Roger Y. ; et al.	2003-10-02
Fluorescent protein sensors for measuring the pH of a biological sample Grant 6,627,449 - Tsien , et al. September 30, 2	2003-09-30
Non-oligomerizing fluorescent proteins App 20030170911 - Tsien, Roger Y. ; et al.	2003-09-11
Detector and screening device for ion channels Grant 6,608,671 - Tsien , et al. August 19, 2	2003-08-19
Fluorescent protein sensors for measuring the pH of a biological sample Grant 6,608,189 - Tsien , et al. August 19, 2	2003-08-19
Detection of transmembrane potentials by optical methods App 20030129670 - Tsien, Roger Y. ; et al.	2003-07-10
Substrates for beta-lactamase and uses thereof App 20030119085 - Tsien, Roger Y. ; et al.	2003-06-26
Synthetic molecules that specifically react with target sequences App 20030083373 - Tsien, Roger Y. ; et al.	2003-05-01
Monomeric and dimeric fluorescent protein variants and methods for making same App 20030059835 - Tsien, Roger Y. ; et al.	2003-03-27
Multi-well platforms, caddies, lids and combinations thereof App 20030039591 - Pham, Andrew A. ; et al.	2003-02-27
Long wavelength engineered fluorescent proteins App 20030036178 - Tsien, Roger Y. ; et al.	2003-02-20
Non-oligomerizing tandem fluorescent proteins App 20030032088 - Tsien, Roger Y. ; et al.	2003-02-13
Beta-lactamase substrates having phenolic ethers App 20030003526 - Tsien, Roger Y. ; et al.	2003-01-02
Tandem fluorescent protein constructs App 20020164674 - Tsien, Roger Y. ; et al.	2002-11-07
Fluorescent protein sensors for detection of analytes App 20020165364 - Tsien, Roger Y. ; et al.	2002-11-07
Detection of transmembrane potentials by optical methods App 20020164577 - Tsien, Roger Y. ; et al.	2002-11-07
Cytosolic forms for .beta.-lactamase and uses thereof Grant 6,472,205 - Tsien , et al. October 29, 2	2002-10-29
Circularly permuted fluorescent protein indicators App 20020157120 - Tsien, Roger Y. ; et al.	2002-10-24
Low fluorescence assay platforms and related methods for drug discovery App 20020155617 - Pham, Andrew A. ; et al.	2002-10-24
Fluorescent protein indicators Grant 6,469,154 - Tsien , et al. October 22, 2	2002-10-22
Synthetic molecules that specifically react with target sequences Grant 6,451,569 - Tsien , et al. September 17, 2	2002-09-17
Modified green fluorescent proteins App 20020123113 - Tsien, Roger Y. ; et al.	2002-09-05
Fluorescein-based metal sensors, and methods of making and using the same App 20020106697 - Lippard, Stephen J. ; et al.	2002-08-08
Multi-well platforms, caddies, lids and combinations thereof Grant 6,426,050 - Pham , et al. July 30, 2	2002-07-30
Assays for protein kinases using fluorescent protein substrates App 20020061546 - Tsien, Roger Y. ; et al.	2002-05-23
Protecting Groups With Increased Photosensitivities App 20020016472 - TSIEN, ROGER Y. ; et al.	2002-02-07
Detection of transmembrane potentials by optical methods Grant 6,342,379 - Tsien , et al. January 29, 2	2002-01-29
Detector And Screening Device For Ion Channels App 20020008867 - TSIEN, ROGER Y. ; et al.	2002-01-24
Detector And Screening Device For Ion Channels App 20020001075 - TSIEN, ROGER Y. ; et al.	2002-01-03
Modified green fluorescent proteins Grant 6,319,669 - Tsien , et al. November 20, 2	2001-11-20
Cytosolic forms of beta-lactamase and uses thereof Grant 6,291,162 - Tsien , et al. September 18, 2	2001-09-18
Photon reducing agents for fluorescence assays App 20010006820 - Knapp, Tom ; et al.	2001-07-05
Assays for protein kinases using fluorescent protein substrates Grant 6,248,550 - Tsien , et al. June 19, 2	2001-06-19
Low background multi-well plates for fluorescence measurements of biological and biochemical samples Grant 6,232,114 - Coassin , et al. May 15, 2	2001-05-15
Low background multi-well plates with greater than 864 wells for spectroscopic measurements Grant 6,229,603 - Coassin , et al. May 8, 2	2001-05-08
Photon reducing agents for use in fluorescence assays Grant 6,221,612 - Knapp , et al. April 24, 2	2001-04-24
Photon reducing agents for reducing undesired light emission in assays Grant 6,214,563 - Negulescu , et al. April 10, 2	2001-04-10
Fluorescent protein sensors for detection of analytes Grant 6,197,928 - Tsien , et al. March 6, 2	2001-03-06
Low fluorescence assay platforms and related methods for drug discovery Grant 6,171,780 - Pham , et al. January 9, 2	2001-01-09
Fluorescent protein sensors for measuring the pH of a biological sample Grant 6,150,176 - Tsien , et al. November 21, 2	2000-11-21
Fluorescent protein sensors for measuring the pH of a biological sample Grant 6,140,132 - Tsien , et al. October 31, 2	2000-10-31
Long wavelength engineered fluorescent proteins Grant 6,124,128 - Tsien , et al. September 26, 2	2000-09-26
Detection of transmembrane potentials by optical methods Grant 6,107,066 - Tsien , et al. August 22, 2	2000-08-22
Long wavelength engineered fluorescent proteins Grant 6,077,707 - Tsien , et al. June 20, 2	2000-06-20
Modified green fluorescent proteins Grant 6,066,476 - Tsien , et al. May 23, 2	2000-05-23
Methods of using synthetic molecules and target sequences Grant 6,054,271 - Tsien , et al. April 25, 2	2000-04-25
Long wavelength engineered fluorescent proteins Grant 6,054,321 - Tsien , et al. April 25, 2	2000-04-25
Photochromic fluorescent proteins and optical memory storage devices based on fluorescent proteins Grant 6,046,925 - Tsien , et al. April 4, 2	2000-04-04
Beta-lactam substrates and uses thereof Grant 6,031,094 - Tsien , et al. February 29, 2	2000-02-29
Synthetic molecules that specifically react with target sequences Grant 6,008,378 - Tsien , et al. December 28, 1	1999-12-28
Fluorescent protein sensors for detection of analytes Grant 5,998,204 - Tsien , et al. December 7, 1	1999-12-07
Tandem fluorescent protein constructs Grant 5,981,200 - Tsien , et al. November 9, 1	1999-11-09
Substrates for .beta.-lactamase and uses thereof Grant 5,955,604 - Tsien , et al. September 21, 1	1999-09-21
Target sequences for synthetic molecules Grant 5,932,474 - Tsien , et al. August 3, 1	1999-08-03
Assays for protein kinases using fluorescent protein substrates Grant 5,925,558 - Tsien , et al. July 20, 1	1999-07-20
Assays for protein kinases using fluorescent Grant 5,912,137 - Tsien , et al. June 15, 1	1999-06-15
Low background multi-well plates with greater than 864 wells for fluorescence measurements of biological and biochemical samples Grant 5,910,287 - Cassin , et al. June 8, 1	1999-06-08
Caged membrane-permeant inositol phosphates Grant 5,866,548 - Tsien , et al. February 2, 1	1999-02-02
Modified green fluorescent proteins Grant 5,777,079 - Tsien , et al. July 7, 1	1998-07-07
Fluorogenic substrates for .beta.-lactamase and methods of use Grant 5,741,657 - Tsien , et al. April 21, 1	1998-04-21
Voltage sensing by fluorescence resonance energy transfer Grant 5,661,035 - Tsien , et al. August 26, 1	1997-08-26
Modified green fluorescent proteins Grant 5,625,048 - Tsien , et al. April 29, 1	1997-04-29
Detection of analytes using fluorescent energy transfer Grant 5,439,797 - Tsien , et al. August 8, 1	1995-08-08
Compounds which release nitric oxide upon illumination Grant 5,374,710 - Tsien , et al. December 20, 1	1994-12-20
Scanning confocal microscope using fluorescence detection Grant 5,296,703 - Tsien March 22, 1	1994-03-22
Scanning confocal microscope providing a continuous display Grant 5,283,433 - Tsien February 1, 1	1994-02-01
Fluorescent indicator dyes for alkali metal cations Grant 5,134,232 - Tsien , et al. July 28, 1	1992-07-28
Fluorescent indicator dyes for calcium working at long wavelengths Grant 5,049,673 - Tsien , et al. September 17, 1	1991-09-17
Chelators whose affinity for calcium is decreased by illumination Grant 4,689,432 - Tsien , et al. August 25, 1	1987-08-25
Fluorescent indicator dyes for calcium ions Grant 4,603,209 - Tsien , et al. July 29, 1	1986-07-29