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Wdr5-myc Inhibitors App 20220289673 - Tansey; William P. ;   et al. | 2022-09-15 |
Allosteric Activators Of The Alpha1a-adrenergic Receptor App 20220227717 - PEREZ; Dianne M. ;   et al. | 2022-07-21 |
WDR5 inhibitors and modulators Grant 10,844,044 - Alvarado , et al. November 24, 2 | 2020-11-24 |
WDR5-MLL1 inhibitors and modulators Grant 10,807,959 - Gogliotti , et al. October 20, 2 | 2020-10-20 |
Wdr5 Inhibitors And Modulators App 20200102288 - Alvarado; Joseph R. ;   et al. | 2020-04-02 |
Wdr5-mll1 Inhibitors And Modulators App 20200055824 - Gogliotti; Rocco D. ;   et al. | 2020-02-20 |
WDR5 inhibitors and modulators Grant 10,501,466 - Fesik , et al. Dec | 2019-12-10 |
Substituted And Fused 6-membered Protease Activated Receptor 4 (par-4) Antagonists App 20190119300 - Hamm; Heidi E. ;   et al. | 2019-04-25 |
Wdr5 Inhibitors And Modulators App 20190084988 - Fesik; Stephen W. ;   et al. | 2019-03-21 |
WDR5 inhibitors and modulators Grant 10,160,763 - Fesik , et al. Dec | 2018-12-25 |
Substituted 5-membered heterocyclic analogs as protease activated receptor 4 (PAR-4) antagonists Grant 9,963,466 - Hamm , et al. May 8, 2 | 2018-05-08 |
Wdr5 Inhibitors And Modulators App 20180086767 - Fesik; Stephen W. ;   et al. | 2018-03-29 |
Substituted 5-Membered Heterocyclic Analogs as Protease Activated Receptor 4 (PAR-4) Antagonists App 20170253617 - Hamm; Heidi E. ;   et al. | 2017-09-07 |
Substituted 4-benzyl-3,4-dihydro-2H-benzo[B][1,4]oxazine-2-carboxamide analogs as positive allosteric modulators of muscarinic acetycholine receptor M1 Grant 9,708,278 - Lindsley , et al. July 18, 2 | 2017-07-18 |
Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists Grant 9,572,794 - Hamm , et al. February 21, 2 | 2017-02-21 |
Substituted 4-benzyl-3,4-dihydro-2h-benzo[b][1,4]oxazine-2carboxamide Analogs As Positive Allosteric Modulators Of Muscarinic Acetycholine Receptor M1 App 20170022173 - Lindsley; Craig W. ;   et al. | 2017-01-26 |
Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1 Grant 9,540,371 - Lindsley , et al. January 10, 2 | 2017-01-10 |
Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 Grant 9,527,834 - Lindsley , et al. December 27, 2 | 2016-12-27 |
Substituted 3-benzylquinoxalin-4(3h)-one Analogs As Positive Allosteric Modulators Of Muscarinic Acetycholine Receptor M1 App 20160102090 - Lindsley; Craig W. ;   et al. | 2016-04-14 |
Substituted Indoles as Selective Protease Activated Receptor 4 (PAR-4) Antagonists App 20160083363 - Hamm; Heidi E. ;   et al. | 2016-03-24 |
Substituted 1-benzylquinoxalin-2(1h) Analogs As Positive Allosteric Modulators Of Muscarinic Acetylcholine Receptor M1 App 20160075690 - Lindsley; Craig W. ;   et al. | 2016-03-17 |
Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators Grant 9,255,103 - Conn , et al. February 9, 2 | 2016-02-09 |
P2X3 receptor antagonists for treatment of pain Grant 9,238,647 - Burgey , et al. January 19, 2 | 2016-01-19 |
Menin-MLL inhibitors and methods of use thereof Grant 9,212,180 - Grembecka , et al. December 15, 2 | 2015-12-15 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20150216863 - Conn; P. Jeffrey ;   et al. | 2015-08-06 |
Bicyclic oxazole and thiazole compounds and their use as allosteric modulators of mGluR5 receptors Grant 9,090,632 - Conn , et al. July 28, 2 | 2015-07-28 |
Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors Grant 9,029,366 - Conn , et al. May 12, 2 | 2015-05-12 |
Substituted 6-methylnicotinamides as mGluR5 positive allosteric modulators Grant 8,969,389 - Conn , et al. March 3, 2 | 2015-03-03 |
Menin-mll Inhibitors And Methods Of Use Thereof App 20140371239 - Grembecka; Jolanta ;   et al. | 2014-12-18 |
Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors Grant 8,901,125 - Conn , et al. December 2, 2 | 2014-12-02 |
Substituted Imidazopyrimidin-5(6h)-ones As Allosteric Modulators Of Mglur5 Receptors App 20140329838 - Conn; P. Jeffrey ;   et al. | 2014-11-06 |
Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors Grant 8,865,725 - Conn , et al. October 21, 2 | 2014-10-21 |
Naphthyridinone analogs as mGluR5 positive allosteric modulators Grant 8,853,237 - Conn , et al. October 7, 2 | 2014-10-07 |
Bicyclic Pyrazole Compounds As Allosteric Modulators Of Mglur5 Receptors App 20140213593 - Conn; P. Jeffrey ;   et al. | 2014-07-31 |
Dihydronaphthyridinyl(organo)methanone analogs as positive allosteric mGluR5 modulators Grant 8,710,074 - Conn , et al. April 29, 2 | 2014-04-29 |
Substituted pyrazolo[1,5-A]pyrazine compounds as allosteric modulators of mGluR5 receptors Grant 8,703,946 - Conn , et al. April 22, 2 | 2014-04-22 |
Bicyclic Triazole And Pyrazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20140057870 - Conn; P. Jeffrey ;   et al. | 2014-02-27 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345203 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Alkoxy Pyrazole Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345206 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Cycloalkyl Pyrazole Lactam Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345204 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Substituted Bicyclic Aralkyl Pyrazole Lactam Analogs As Allosteric Modulators Of Mglur5 Receptors App 20130345205 - Conn; P. Jeffrey ;   et al. | 2013-12-26 |
Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors Grant 8,592,422 - Conn , et al. November 26, 2 | 2013-11-26 |
Bicyclic Oxazole And Thiazole Compounds And Their Use As Allosteric Modulators Of Mglur5 Receptors App 20130261107 - Conn; P. Jeffrey ;   et al. | 2013-10-03 |
Bicyclic Oxazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20130252943 - Conn; P. Jeffrey ;   et al. | 2013-09-26 |
Substituted Imidazopyrimidin-5(6h)-ones As Allosteric Modulators Of Mglur5 Receptors App 20130245043 - Conn; P. Jeffrey ;   et al. | 2013-09-19 |
Macrocyclic spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease Grant 8,399,473 - Nantermet , et al. March 19, 2 | 2013-03-19 |
2,3,4,6-substituted pyridyl derivative compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease Grant 8,394,837 - Nantermet , et al. March 12, 2 | 2013-03-12 |
Bicyclic spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease Grant 8,377,954 - Stauffer , et al. February 19, 2 | 2013-02-19 |
Tertiary carbinamines having substituted heterocycles which are active as .beta.-secretase inhibitors for the treatment of alzheimer's disease Grant 8,338,614 - McGaughey , et al. December 25, 2 | 2012-12-25 |
Bicyclic Pyrazole Compounds As Allosteric Modulators Of Mglur5 Receptors App 20120295913 - Conn; P. Jeffrey ;   et al. | 2012-11-22 |
Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease Grant 8,293,759 - Stauffer , et al. October 23, 2 | 2012-10-23 |
Bicyclic Triazole And Pyrazole Lactams As Allosteric Modulators Of Mglur5 Receptors App 20120225844 - Conn; P. Jeffrey ;   et al. | 2012-09-06 |
Dihydronaphthyridinyl(organo)methanone Analogs As Positive Allosteric Mglur5 Modulators App 20120178776 - Conn; P. Jeffrey ;   et al. | 2012-07-12 |
Naphthyridinone Analogs As Mglur5 Positive Allosteric Modulators App 20120172391 - Conn; P. Jeffrey ;   et al. | 2012-07-05 |
Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease Grant 8,211,904 - Coburn , et al. July 3, 2 | 2012-07-03 |
Piperidine and pyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease Grant 8,143,405 - Stauffer March 27, 2 | 2012-03-27 |
P2X3 Receptor Antagonists for Treatment of Pain App 20120064181 - Burgey; Christopher S. ;   et al. | 2012-03-15 |
Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease Grant 8,114,887 - Barrow , et al. February 14, 2 | 2012-02-14 |
Substituted 6-methylnicotinamides As Mglur5 Positive Allosteric Modulators App 20110294858 - Conn; P. Jeffrey ;   et al. | 2011-12-01 |
2,4,6-substituted pyridyl derivative compounds useful as beta-secretase inhibitors for the treatment of Alzheimer's Disease Grant 7,968,571 - Barrow , et al. June 28, 2 | 2011-06-28 |
1,3,5-substituted phenyl derivative compounds useful as beta-secretase inhibitors for the treatment of Alzheimer's disease Grant 7,847,100 - Barrow , et al. December 7, 2 | 2010-12-07 |
Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's Disease App 20100298342 - Egbertson; Melissa S. ;   et al. | 2010-11-25 |
Aminomethyl beta-secretase inhibitors for the treatment of alzheimer's disease Grant 7,820,674 - Coburn , et al. October 26, 2 | 2010-10-26 |
Bicyclic Spiropiperidine Beta-secretase Inhibitors For The Treatment Of Alzheimer's Disease App 20100076004 - Stauffer; Shaun R. ;   et al. | 2010-03-25 |
Spiropiperidine Beta-secretase Inhibitors For The Treatment Of Alzheimer's Disease App 20100069419 - Stauffer; Shaun R. ;   et al. | 2010-03-18 |
Piperidine and pyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease App 20100041667 - Stauffer; Shaun R. | 2010-02-18 |
Macrocyclic Spiropiperidine Beta-secretase Inhibitors For The Treatment Of Alzheimer's Disease App 20100029701 - Nantermet; Philippe G. ;   et al. | 2010-02-04 |
Phenylamide and pyridylamide beta-secretase inhibitors for the treatment of Alzheimer's disease Grant 7,550,481 - Barrow , et al. June 23, 2 | 2009-06-23 |
Aminomethyl Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease App 20080153846 - Coburn; Craig A. ;   et al. | 2008-06-26 |
Tertiary Carbinamines Having Substituted Heterocycles Which Are Active As Beta-Secretase Inhibitors For The Treatment Of Alzheimer's Disease App 20080139538 - McGaughey; Georgia B. ;   et al. | 2008-06-12 |
Benzylether and benzylamino beta-secretase inhibitors for the treatment of Alzheimer's disease Grant 7,354,942 - Nantermet , et al. April 8, 2 | 2008-04-08 |
2,4,6-Substituted Pyridyl Derivative Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease App 20080015233 - Barrow; James C. ;   et al. | 2008-01-17 |
2,3,4,6-Substituted Pyridyl Derivative Compounds Useful As Beta-Secretase Inhibitors For The Treatment Of Alzheimer's Disease App 20070293497 - Nantermet; Philippe G. ;   et al. | 2007-12-20 |
1,3,5-Substituted Phenyl Derivative Compounds Useful as Beta-Secretase Inhibitors for the Treatment of Alzheimer's Disease App 20070244119 - Barrow; James C. ;   et al. | 2007-10-18 |
Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of alzheimer' s disease App 20070197571 - Barrow; James C. ;   et al. | 2007-08-23 |
Phenylamide and pyridylamide beta-secretase inhibitors for the treatment of alzheimer's disease App 20070142634 - Barrow; James C. ;   et al. | 2007-06-21 |
Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer's disease App 20070088165 - Nantermet; Philippe G. ;   et al. | 2007-04-19 |
Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease App 20070021454 - Coburn; Craig A. ;   et al. | 2007-01-25 |