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Preparation and Use of Cyclic Sulfonamide Derivatives as PAR-1 Receptor Antagonists App 20170240539 - Stamford; Andrew W. ;   et al. | 2017-08-24 |
Processes For The Preparation Of A Bace Inhibitor App 20170233382 - Miller; Steven P. ;   et al. | 2017-08-17 |
Fused Tricyclic Heterocyclic Compounds As Hiv Integrase Inhibitors App 20170190701 - Yu; Tao ;   et al. | 2017-07-06 |
6,7-dihydro-5h-pyrrolo[3,4-b]pyridin-5-one Allosteric Modulators Of The M4 Muscarinic Acetylcholine Receptor App 20170183342 - BAO; JIANMING ;   et al. | 2017-06-29 |
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FACTOR XIa INHIBITORS App 20170044183 - Lim; Yeon-Hee ;   et al. | 2017-02-16 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20160367563 - Scott; Jack D. ;   et al. | 2016-12-22 |
5-substituted iminothiazines and their mono- and dioxides as BACE inhibitors, compositions, and their use Grant 9,499,502 - Wu , et al. November 22, 2 | 2016-11-22 |
C6-azaspiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use Grant 9,489,013 - Cumming , et al. November 8, 2 | 2016-11-08 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,475,785 - Scott , et al. October 25, 2 | 2016-10-25 |
C2-azaspiro iminothiazine dioxides as BACE inhibitors, compositions, and their use Grant 9,453,034 - Gilbert , et al. September 27, 2 | 2016-09-27 |
C6-spiro Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160264538 - Cumming; Jared N. ;   et al. | 2016-09-15 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,428,475 - Scott , et al. August 30, 2 | 2016-08-30 |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment Grant 9,422,266 - Miller , et al. August 23, 2 | 2016-08-23 |
Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,422,277 - Gilbert , et al. August 23, 2 | 2016-08-23 |
Tricyclic substituted thiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 9,416,129 - Gilbert , et al. August 16, 2 | 2016-08-16 |
Heterocyclic aspartyl protease inhibitors Grant 9,416,108 - Zhu , et al. August 16, 2 | 2016-08-16 |
Preparation and use of compounds as protease inhibitors Grant 9,382,242 - Stamford , et al. July 5, 2 | 2016-07-05 |
C6-azaspiro Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160043774 - Cumming; Jared N. ;   et al. | 2016-02-11 |
C2-azaspiro Iminothiazine Dioxides As Bace Inhibitors, Compositions, And Their Use App 20160016975 - Gilbert; Eric J. ;   et al. | 2016-01-21 |
C5-C6 oxacyclic-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,221,839 - Cumming , et al. December 29, 2 | 2015-12-29 |
2-spiro-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions and their use Grant 9,181,236 - Wu , et al. November 10, 2 | 2015-11-10 |
Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use App 20150307465 - Scott; Jack D. ;   et al. | 2015-10-29 |
Tricyclic Substituted Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20150284379 - Gilbert; Eric J. ;   et al. | 2015-10-08 |
Tricyclic Substituted Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20150274716 - Gilbert; Eric J. ;   et al. | 2015-10-01 |
Pyrrolidine-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 9,145,426 - Stamford , et al. September 29, 2 | 2015-09-29 |
Iminothiadiazine dioxide compounds as brace inhibitors, compositions, and their use Grant 9,029,362 - Scott , et al. May 12, 2 | 2015-05-12 |
Heterocyclic Aspartyl Protease Inhibitors App 20150105354 - Zhu; Zhaoning ;   et al. | 2015-04-16 |
Substituted cyclopropyl compounds, compositions containing such compounds and methods of treatment Grant 8,957,062 - Edmondson , et al. February 17, 2 | 2015-02-17 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use Grant 8,940,748 - Scott , et al. January 27, 2 | 2015-01-27 |
Heterocyclic aspartyl protease inhibitors Grant 8,937,093 - Saionz , et al. January 20, 2 | 2015-01-20 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140296221 - Scott; Jack D. ;   et al. | 2014-10-02 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140296222 - Scott; Jack D. ;   et al. | 2014-10-02 |
Substituted Cyclopropyl Compounds, Compositions Containing Such Compounds And Methods Of Treatment App 20140256699 - Miller; Michael W. ;   et al. | 2014-09-11 |
Heterocyclic aspartyl protease inhibitors Grant 8,829,036 - Zhu , et al. September 9, 2 | 2014-09-09 |
Bicyclic heterocycle derivatives and use thereof as GPR119 modulators Grant 8,822,480 - Neelamkavil , et al. September 2, 2 | 2014-09-02 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140206675 - Scott; Jack D. ;   et al. | 2014-07-24 |
Preparation And Use Of Compounds As Protease Inhibitors App 20140206715 - Stamford; Andrew W. ;   et al. | 2014-07-24 |
2-spiro-substituted Iminothiazines And Their Mono-and Dioxides As Bace Inhibitors, Compositions And Their Use App 20140200213 - Wu; Wen-Lian ;   et al. | 2014-07-17 |
Pyrrolidines as glucagon receptor antagonists, compositions, and methods for their use Grant 8,735,604 - Gilbert , et al. May 27, 2 | 2014-05-27 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use Grant 8,729,071 - Scott , et al. May 20, 2 | 2014-05-20 |
5-substituted Iminothiazines And Their Mono- And Dioxides As Bace Inhibitors, Compositions, And Their Use App 20140128382 - Wu; Wen-Lian ;   et al. | 2014-05-08 |
Heterocyclic aspartyl protease inhibitors Grant 8,691,833 - Zhu , et al. April 8, 2 | 2014-04-08 |
Heterocyclic aspartyl protease inhibitors Grant 8,691,831 - Zhu , et al. April 8, 2 | 2014-04-08 |
Heterocyclic Aspartyl Protease Inhibitors App 20140057910 - Zhu; Zhaoning ;   et al. | 2014-02-27 |
Substituted Cycloproply Compounds, Compositions Containing Such Compounds And Methods Of Treatment App 20140057893 - Edmondson; Scott ;   et al. | 2014-02-27 |
C5-c6 Oxacyclic-fused Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140023668 - Cumming; Jared N. ;   et al. | 2014-01-23 |
Pyrrolidine-fused Thiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20140023667 - Stamford; Andrew W. ;   et al. | 2014-01-23 |
Pentafluorosulfur imino heterocyclic compounds as BACE-1 inhibitors, compositions and their use Grant 8,569,310 - Iserloh , et al. October 29, 2 | 2013-10-29 |
Iminothiadiazine dioxide compounds as bace inhibitors, compositions, and their use Grant 8,563,543 - Scott , et al. October 22, 2 | 2013-10-22 |
Pentafluorosulfur imino heterocyclic compounds as BACE-1 inhibitors, compositions, and their use Grant 8,557,826 - Stamford , et al. October 15, 2 | 2013-10-15 |
Phenyl-substituted 2-imino-3-methyl pyrrolo pyrimidinone compounds as BACE-1 inhibitors, compositions, and their use Grant 8,541,427 - Stamford , et al. September 24, 2 | 2013-09-24 |
Thiophenes as glucagon receptor antagonists, compositions, and methods for their use Grant 8,470,773 - Gilbert , et al. June 25, 2 | 2013-06-25 |
Substituted [1,2,4]triazolo[4,3-alpha]quinoxalines as adenosine A2a receptor antagonists Grant 8,435,994 - Harris , et al. May 7, 2 | 2013-05-07 |
Amino-quinoxaline and amino-quinoline compounds for use as adenosine A.sub.2a receptor antagonists Grant 8,415,353 - Harris , et al. April 9, 2 | 2013-04-09 |
Substituted Piperazines As Cb1 Antagonists App 20130072468 - Gilbert; Eric J. ;   et al. | 2013-03-21 |
Substituted amide beta secretase inhibitors Grant 8,367,712 - Huang , et al. February 5, 2 | 2013-02-05 |
Novel Spiro Imidazolone Derivatives As Glucagon Receptor Antagonists, Compositions, And Methods For Their Use App 20130012493 - Zhao; He ;   et al. | 2013-01-10 |
Novel Spiro Imidazolones As Glucagon Receptor Antagonists, Compositions, And Methods For Their Use App 20130012434 - Wong; Michael K. ;   et al. | 2013-01-10 |
Pyrimidinone derivatives and methods of use thereof Grant 8,318,751 - Boyle , et al. November 27, 2 | 2012-11-27 |
Heterocyclic aspartyl protease inhibitors Grant 8,242,112 - Zhu , et al. August 14, 2 | 2012-08-14 |
Substituted piperazines as CB.sub.1 antagonists Grant 8,236,805 - Gilbert , et al. August 7, 2 | 2012-08-07 |
Pentafluorosulfur Imino Heterocyclic Compounds As Bace-1 Inhibitors, Compositions And Their Use App 20120195881 - Iserloh; Ulrich ;   et al. | 2012-08-02 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions, And Their Use App 20120189642 - Scott; Jack D. ;   et al. | 2012-07-26 |
Iminothiadiazine Dioxide Compounds As Bace Inhibitors, Compositions And Their Use App 20120183563 - Scott; Jack D. ;   et al. | 2012-07-19 |
1,2,4-triazolo[4,3-c]pyrimidin-3-one and pyrazolo[4,3-e]-1,2,4-triazolo[4,3-c]pyrimidin-3-one compounds for use as adenosine A.sub.2a receptor antagonists Grant 8,222,259 - Harris , et al. July 17, 2 | 2012-07-17 |
Novel Pyrrolidines As Glucagon Receptor Antagonists, Compositions, And Methods For Their Use App 20120178789 - Gilbert; Eric J. ;   et al. | 2012-07-12 |
Heterocyclic aspartyl protease inhibitors Grant 8,202,854 - Zhu , et al. June 19, 2 | 2012-06-19 |
Pentafluorosulfur Imino Heterocyclic Compounds As Bace-1 Inhibitors, Compositions, And Their Use App 20120148603 - Stamford; Andrew W. ;   et al. | 2012-06-14 |
Heterocyclic aspartyl protease inhibitors Grant 8,178,513 - Zhu , et al. May 15, 2 | 2012-05-15 |
Thiophenes As Glucagon Receptor Antagonists, Compositions, And Methods For Their Use App 20120108505 - Gilbert; Eric J. ;   et al. | 2012-05-03 |
Heterocyclic Aspartyl Protease Inhibitors App 20110280867 - Zhu; Zhaoning ;   et al. | 2011-11-17 |
Heterocyclic aspartyl protease inhibitors Grant 8,012,960 - Zhu , et al. September 6, 2 | 2011-09-06 |
Macrocyclic beta-secretase inhibitors Grant 8,012,953 - Stamford , et al. September 6, 2 | 2011-09-06 |
Bicyclic Heterocycle Derivatives And Use Thereof As Gpr119 Modulators App 20110166165 - Neelamkavil; Santhosh Francis ;   et al. | 2011-07-07 |
1,2,4-TRIAZOLO[4,3-c]PYRIMIDIN-3-ONE AND PYRAZOLO[4,3-e]-1,2,4-TRIAZOLO[4,3-c]PYRIMIDIN-3-ONE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS App 20110152256 - Harris; Joel M. ;   et al. | 2011-06-23 |
Thiophenyl-substituted 2-imino-3-methyl Pyrrolo Pyrimidinone Compounds As Bace-1 Inhibitors, Compositions, And Their Use App 20110110927 - Stamford; Andrew W. ;   et al. | 2011-05-12 |
Phenyl-substituted 2-imino-3-methyl Pyrrolo Pyrimidinone Compounds As Bace-1 Inhibitors, Compositions, And Their Use App 20110110957 - Stamford; Andrew W. ;   et al. | 2011-05-12 |
AMINO-QUINOXALINE AND AMINO-QUINOLINE COMPOUNDS FOR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS App 20110105513 - Harris; Joel M. ;   et al. | 2011-05-05 |
Substituted Amide Beta Secretase Inhibitors App 20110003825 - Huang; Ying ;   et al. | 2011-01-06 |
Heterocyclic Aspartyl Protease Inhibitors App 20100247519 - Zhu; Zhaoning ;   et al. | 2010-09-30 |
Substituted amide beta secretase inhibitors Grant 7,803,802 - Huang , et al. September 28, 2 | 2010-09-28 |
Pyrimidinone Derivatives And Methods Of Use Thereof App 20100190687 - Boyle; Craig D. ;   et al. | 2010-07-29 |
Heterocyclic aspartyl protease inhibitors Grant 7,763,606 - Zhu , et al. July 27, 2 | 2010-07-27 |
Macrocyclic Beta-secretase Inhibitors App 20100178294 - Stamford; Andrew W. ;   et al. | 2010-07-15 |
Pyrimidinone Derivatives And Methods Of Use Thereof App 20100113487 - Boyle; Craig D ;   et al. | 2010-05-06 |
Substituted piperazines as CB1 antagonists Grant 7,700,597 - Gilbert , et al. April 20, 2 | 2010-04-20 |
Substituted Piperazines as CB1 Antagonists App 20100029607 - Gilbert; Eric J. ;   et al. | 2010-02-04 |
Macrocyclic .beta.-secretase inhibitors Grant 7,652,003 - Stamford , et al. January 26, 2 | 2010-01-26 |
Aspartyl protease inhibitors Grant 7,560,451 - Zhu , et al. July 14, 2 | 2009-07-14 |
Xanthine phosphodiesterase V inhibitors Grant 7,531,544 - Chackalamannil , et al. May 12, 2 | 2009-05-12 |
Xanthine Phosphodiesterase V Inhibitors App 20080058354 - Chackalamannil; Samuel ;   et al. | 2008-03-06 |
Neuropeptide Y Y5 receptor antagonists Grant 7,304,076 - Stamford , et al. December 4, 2 | 2007-12-04 |
Diaryl piperidines as CB1 modulators App 20070203183 - Scott; Jack D. ;   et al. | 2007-08-30 |
Heterocyclic aspartyl protease inhibitors App 20070099898 - Zhu; Zhaoning ;   et al. | 2007-05-03 |
Aspartyl protease inhibitors App 20070099875 - Zhu; Zhaoning ;   et al. | 2007-05-03 |
Neuropeptide Y Y5 receptor antagonists Grant 7,157,472 - Stamford , et al. January 2, 2 | 2007-01-02 |
Substituted piperazines as CB1 antagonists App 20060241121 - Greenlee; William J. ;   et al. | 2006-10-26 |
Macrocyclic beta-secretase inhibitors App 20060040948 - Stamford; Andrew W. ;   et al. | 2006-02-23 |
Substituted amide beta secretase inhibitors App 20060040994 - Huang; Ying ;   et al. | 2006-02-23 |
Polycyclic guanine derivative phosphodiesterase V inhibitors Grant 6,943,171 - Asberom , et al. September 13, 2 | 2005-09-13 |
Xanthine phosphodiesterase V inhibitors App 20050182077 - Chackalamannil, Samuel ;   et al. | 2005-08-18 |
Polycyclic guanine derivative phosphodiesterase V inhibitors App 20050171129 - Asberom, Theodros ;   et al. | 2005-08-04 |
Substituted urea neuropeptide Y Y5 Receptor antagonists Grant 6,894,063 - Greenlee , et al. May 17, 2 | 2005-05-17 |
Xanthine phosphodiesterase V inhibitors App 20050075349 - Chackalamannil, Samuel ;   et al. | 2005-04-07 |
Xanthine phosphodiesterase V inhibitors Grant 6,821,978 - Chackalamannil , et al. November 23, 2 | 2004-11-23 |
Xanthine phosphodiesterase V inhibitors App 20040229885 - Chackalamannil, Samuel ;   et al. | 2004-11-18 |
Xanthine phosphodiesterase V inhibitors App 20040167137 - Chackalamannil, Samuel ;   et al. | 2004-08-26 |
New neuropeptide Y Y5 receptor antagonists App 20040102474 - Stamford, Andrew W. ;   et al. | 2004-05-27 |
New neuropeptide Y Y5 receptor antagonists App 20040034008 - Stamford, Andrew W. ;   et al. | 2004-02-19 |
Neuropeptide Y Y5 receptor antagonists Grant 6,667,319 - Stamford , et al. December 23, 2 | 2003-12-23 |
Neuropeptide Y Y5 receptor antagonists App 20030207860 - Stamford, Andrew W. ;   et al. | 2003-11-06 |
Substituted imidazole neuropeptide Y Y5 receptor antagonists Grant 6,632,828 - Stamford , et al. October 14, 2 | 2003-10-14 |
Polycyclic guanine derivative phosphodiesterase V inhibitors App 20030176413 - Asberom, Theodros ;   et al. | 2003-09-18 |
Substituted imidazole neuropeptide Y Y5 receptor antagonists App 20030114465 - Stamford, Andrew W. ;   et al. | 2003-06-19 |
Substituted urea neuropeptide Y Y5 receptor antagonists App 20030114517 - Greenlee, William J. ;   et al. | 2003-06-19 |
Xanthine phosphodiesterase V inhibitors App 20020169174 - Chackalamannil, Samuel ;   et al. | 2002-11-14 |
Substituted urea neuropeptide Y Y5 receptor antagonists App 20020165223 - Greenlee, William J. ;   et al. | 2002-11-07 |
Neuropeptide Y5 receptor antagonists Grant 6,329,395 - Dugar , et al. December 11, 2 | 2001-12-11 |
Derivatives of phosphinic acid useful as endothelin converting enzyme inhibitors Grant 5,476,847 - McKittrick , et al. December 19, 1 | 1995-12-19 |