| Patent | Date |
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1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer
Grant 10,167,282 - Springer , et al. J | 2019-01-01 |
Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivatives
Grant 10,100,053 - Zambon , et al. October 16, 2 | 2018-10-16 |
1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,- 3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy
Grant 9,820,976 - Springer , et al. November 21, 2 | 2017-11-21 |
1 -(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4h-pyrido[2, 3-b]pyrazin-8-yl)oxy]phenyl]urea Derivatives As Raf Inhibitors For The Treatment Of Cancer
App 20170298066 - SPRINGER; Caroline Joy ; et al. | 2017-10-19 |
Process For The Preparation Of 8-(4-aminophenoxy)-4h-pyrido[2,3-b]pyrazin-3-one Derivatives
App 20170298065 - Zambon; Alfonso ; et al. | 2017-10-19 |
1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b- ]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer
Grant 9,725,447 - Springer , et al. August 8, 2 | 2017-08-08 |
Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives
Grant 9,708,317 - Zambon , et al. July 18, 2 | 2017-07-18 |
1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,- 3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea And Related Compounds And Their Use In Therapy
App 20170079963 - SPRINGER; Caroline Joy ; et al. | 2017-03-23 |
Pyrido[2,3-b]pyrazin-8-substituted compounds and their use
Grant 9,540,372 - Springer , et al. January 10, 2 | 2017-01-10 |
1 -(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4h-pyrido[2, 3-b]pyrazin-8-yl)oxy]phenyl]urea Derivatives As Raf Inhibitors For The Treatment Of Cancer
App 20160355510 - SPRINGER; Caroline Joy ; et al. | 2016-12-08 |
Process For The Preparation Of 8-(4-aminophenoxy)-4h-pyrido[2,3-b]pyrazin-3-one Derivatives
App 20160297814 - Zambon; Alfonso ; et al. | 2016-10-13 |
Pyrido[2,3-b]pyrazin-8-substituted Compounds And Their Use
App 20160002230 - SPRINGER; Caroline Joy ; et al. | 2016-01-07 |
Pyrido[2,3-B]pyrazin-8-substituted compounds and their use
Grant 9,155,737 - Springer , et al. October 13, 2 | 2015-10-13 |
Pyrido[2,3-b]pyrazin-8-substituted Compounds And Their Use
App 20150182526 - SPRINGER; Caroline Joy ; et al. | 2015-07-02 |
Pyrido[2,3-B]pyrazin-8-substituted compounds and their use
Grant 8,912,191 - Springer , et al. December 16, 2 | 2014-12-16 |
Pyrido[2,3-b]pyrazin-8-substituted Compounds and Their Use
App 20140121212 - Springer; Caroline Joy ; et al. | 2014-05-01 |
Pyrido[2,3-b]pyrazin-8-substituted compounds and their use
Grant 8,546,387 - Springer , et al. October 1, 2 | 2013-10-01 |
Aryl-quinolyl compounds and their use
Grant 8,383,816 - Niculescu-Duvaz , et al. February 26, 2 | 2013-02-26 |
Pyrido[2,3-b]pyrazin-8-substituted Compounds and Their Use
App 20120238568 - Springer; Caroline Joy ; et al. | 2012-09-20 |
Pyrido[2,3-b]pyrazin-8-substituted compounds and their use
Grant 8,198,279 - Springer , et al. June 12, 2 | 2012-06-12 |
Imidazo[4, 5-B]pyridin-2-one and oxazolo[4, 5-B] pyridin-2-one compounds and analogs thereof as cancer therapeutic compounds
Grant 7,951,819 - Niculescu-Duvaz , et al. May 31, 2 | 2011-05-31 |
Aryl-Quinolyl Compounds and Their Use
App 20110053946 - Niculescu-Duvaz; Ion ; et al. | 2011-03-03 |
Pyrido[2,3-b]pyrazin-8-substituted Compounds and Their Use
App 20100298320 - Springer; Caroline Joy ; et al. | 2010-11-25 |
6-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compounds
Grant 7,737,152 - Springer , et al. June 15, 2 | 2010-06-15 |
Imidazo[4, 5-b]pyridin-2-one And Oxazolo[4, 5-b]pyridin-2-one Compounds And Analogs Thereof As Cancer Therapeutic Compounds
App 20090325945 - Niculescu-Duvaz; Dan ; et al. | 2009-12-31 |
Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds
Grant 7,625,922 - Niculescu-Duvaz , et al. December 1, 2 | 2009-12-01 |
Pyrazines and Pyridines and Derivatives Thereof as Therapeutic Compounds
App 20080015191 - Springer; Caroline Joy ; et al. | 2008-01-17 |
Imidazo[4,5-B]Pyridin-2-One and Oxazolo[4,5-B]Pyridin-2-One Compounds and Analogs Thereof as Therapeutic Compounds
App 20070287838 - Niculescu-Duvaz; Dan ; et al. | 2007-12-13 |
Methods of chemical systhesis of phenolic nitrogen mustard prodrugs
Grant 6,916,949 - Springer , et al. July 12, 2 | 2005-07-12 |
Methods of chemical systhesis of phenolic nitrogen mustard prodrugs
App 20040087813 - Springer, Caroline Joy ; et al. | 2004-05-06 |
Bacterial carboxypeptidase cpg2 variants and their use in gene directed enzyme prodrug therapy
App 20040014187 - Springer, Caroline Joy ; et al. | 2004-01-22 |
Surface expression of enzyme in gene directed prodrug therapy
Grant 6,025,340 - Springer , et al. February 15, 2 | 2000-02-15 |
Nitrogen mustard prodrugs with novel lipophilic protecting groups, and processes for their production
Grant 6,005,002 - Springer , et al. December 21, 1 | 1999-12-21 |
Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form
Grant 5,780,585 - Anlezark , et al. July 14, 1 | 1998-07-14 |
Prodrugs of protein tyrosine kinase inhibitors
Grant 5,728,868 - Springer , et al. March 17, 1 | 1998-03-17 |
Drug delivery systems
Grant 5,716,990 - Bagshawe , et al. February 10, 1 | 1998-02-10 |
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