Patent | Date |
---|
(S)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetra- fluorophenoxy)pentanoic acid derivatives and related compounds as caspase inhibitors for treating cardiovascular diseases Grant 11,447,497 - Spada , et al. September 20, 2 | 2022-09-20 |
(s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetra- Fluorophenoxy)pentanoic Acid Derivatives And Related Compounds As Caspase Inhibitors For Treating Cardiovascular Diseases App 20210277014 - Spada; Alfred P. ;   et al. | 2021-09-09 |
Caspase Inhibitors And Methods Of Use Thereof App 20200283396 - Spada; Alfred P. ;   et al. | 2020-09-10 |
Methods Of Using Caspase Inhibitors In Treatment Of Liver Disease App 20190022043 - Spada; Alfred P. | 2019-01-24 |
Treatment Of The Complications Of Chronic Liver Disease With Caspase Inhibitors App 20170100448 - SPADA; Alfred P. | 2017-04-13 |
Treatment Of The Complications Of Chronic Liver Disease App 20160213736 - SPADA; Alfred P. | 2016-07-28 |
Combination Therapy For The Treatment Of Liver Diseases App 20110212056 - Spada; Alfred P. | 2011-09-01 |
Tetrapeptide analogs App 20100190688 - Chao; Bin ;   et al. | 2010-07-29 |
Substituted oxoazaheterocyclyl compounds Grant 7,612,075 - Ewing , et al. November 3, 2 | 2009-11-03 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 7,550,597 - Myers , et al. June 23, 2 | 2009-06-23 |
Combination therapy for the treatment of liver diseases App 20080207605 - Spada; Alfred P. | 2008-08-28 |
Methods for the treatment of liver diseases App 20080207569 - Spada; Alfred P. | 2008-08-28 |
Anti-vascular and anti-proliferation methods, therapies, and combinations employing specific tyrosine kinase inhibitors App 20070197538 - Nesbit; Mark ;   et al. | 2007-08-23 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases App 20050182054 - Myers, Michael R. ;   et al. | 2005-08-18 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,852,712 - Myers , et al. February 8, 2 | 2005-02-08 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,846,815 - Myers , et al. January 25, 2 | 2005-01-25 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and /or p56lck tyrosine kinases Grant 6,821,962 - Myers , et al. November 23, 2 | 2004-11-23 |
Substituted oxoazaheterocyclyl compounds App 20040102450 - Ewing, William R. ;   et al. | 2004-05-27 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,696,434 - Myers , et al. February 24, 2 | 2004-02-24 |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase App 20040014774 - Myers, Michael R. ;   et al. | 2004-01-22 |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase Grant 6,645,969 - Myers , et al. November 11, 2 | 2003-11-11 |
Methods of treating insulin resistance syndrome and diabetes App 20030176390 - Herling, Andreas ;   et al. | 2003-09-18 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases App 20030144284 - Myers, Michael R. ;   et al. | 2003-07-31 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases App 20030139399 - Myers, Michael R. ;   et al. | 2003-07-24 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and /or p56lck tyrosine kinases App 20030139400 - Myers, Michael R. ;   et al. | 2003-07-24 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases App 20030130285 - Myers, Michael R. ;   et al. | 2003-07-10 |
Compounds having antihypertensive, cardioprotective anti-ischemic and antilipolytic properties Grant 6,559,313 - Myers , et al. May 6, 2 | 2003-05-06 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,528,526 - Myers , et al. March 4, 2 | 2003-03-04 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,524,347 - Myers , et al. February 25, 2 | 2003-02-25 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,482,834 - Spada , et al. November 19, 2 | 2002-11-19 |
Compounds having antihypertensive, cardioprotective anti-ischemic and antilipolytic properties App 20020099030 - Myers, Michael R. ;   et al. | 2002-07-25 |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase Grant RE37,650 - Myers , et al. April 9, 2 | 2002-04-09 |
Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides Grant 6,323,227 - Klein , et al. November 27, 2 | 2001-11-27 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases App 20010023250 - Spada, Alfred P. ;   et al. | 2001-09-20 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,245,760 - He , et al. June 12, 2 | 2001-06-12 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56lck tyrosine kinases Grant 6,180,632 - Myers , et al. January 30, 2 | 2001-01-30 |
Quinoline and quinoxaline compounds which inhibit platelet-derived growth factor and/or p56.sup.lck tyrosine kinases Grant 6,159,978 - Myers , et al. December 12, 2 | 2000-12-12 |
Substituted n-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides Grant 6,080,767 - Klein , et al. June 27, 2 | 2000-06-27 |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 6,057,320 - Spada , et al. May 2, 2 | 2000-05-02 |
Substituted sulfonic acid N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds Grant 6,034,093 - Ewing , et al. March 7, 2 | 2000-03-07 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant RE36,256 - Spada , et al. July 20, 1 | 1999-07-20 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,795,889 - Spada , et al. August 18, 1 | 1998-08-18 |
Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties Grant 5,736,554 - Spada , et al. April 7, 1 | 1998-04-07 |
Protein tyrosine kinase aryl and heteroaryl quinazoline compounds having selective inhibition of HER-2 autophosphorylation properties Grant 5,721,237 - Myers , et al. February 24, 1 | 1998-02-24 |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase Grant 5,714,493 - Myers , et al. February 3, 1 | 1998-02-03 |
Aryl and heteroaryl quinazoline compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,710,158 - Myers , et al. January 20, 1 | 1998-01-20 |
Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit EGF receptor tyrosine kinase Grant 5,677,329 - Spada , et al. October 14, 1 | 1997-10-14 |
Bis mono-and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,656,643 - Spada , et al. A | 1997-08-12 |
Styryl-substituted heteroaryl compounds which inhibit EGF receptor tyrosine kinase Grant 5,656,655 - Spada , et al. August 12, 1 | 1997-08-12 |
DI (1R)-(-)camphosulfonic acid) salt, preparation thereof and use thereof Grant 5,652,366 - Spada , et al. July 29, 1 | 1997-07-29 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,646,153 - Spada , et al. July 8, 1 | 1997-07-08 |
Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds Grant 5,612,353 - Ewing , et al. March 18, 1 | 1997-03-18 |
Method and composition for treating psoriasis with styryl-substituted pyridyl compounds Grant 5,597,837 - Spada , et al. January 28, 1 | 1997-01-28 |
Compounds having antihypertensive, cardioprotective, anti-ischemic and antilipolytic properties Grant 5,561,134 - Spada , et al. October 1, 1 | 1996-10-01 |
Polyarylcarbamoylaza- and -carbamoylalkanedioic acids Grant 5,556,990 - Pauls , et al. September 17, 1 | 1996-09-17 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,480,883 - Spada , et al. January 2, 1 | 1996-01-02 |
Styryl-substituted monocyclic and bicyclic heteroaryl compounds which inhibit EGF receptor tyrosine kinase Grant 5,418,245 - Spada , et al. May 23, 1 | 1995-05-23 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase Grant 5,409,930 - Spada , et al. | 1995-04-25 |
Compounds having antihypertensive and anti-ischemic properties Grant 5,364,862 - Spada , et al. November 15, 1 | 1994-11-15 |
Styryl-substituted pyridyl compounds which inhibit EGF receptor tyrosine kinase Grant 5,302,606 - Spada , et al. April 12, 1 | 1994-04-12 |
Naphtheridinone- and pyridooxazinone-pyridone compounds, cardiotonic compositions including same, and their uses Grant 5,015,638 - Spada , et al. * May 14, 1 | 1991-05-14 |
Naphtheridinone- and pyridooxazinone-pyridone compounds, cardiotonic compositions including same, and their uses Grant 4,866,074 - Spada , et al. September 12, 1 | 1989-09-12 |
Pyrido[2,3-d]pyrimidinone and imidazo[4,5-b]pyrimidinone Grant 4,859,672 - Spada , et al. August 22, 1 | 1989-08-22 |