Patent | Date |
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Anti-cancer combination therapy Grant 11,198,726 - Hilberg , et al. December 14, 2 | 2021-12-14 |
Anticancer Combination Therapy App 20190125751 - SOLCA; Flavio ;   et al. | 2019-05-02 |
Quinazoline Derivatives For The Treatment Of Cancer Diseases App 20180360834 - SOLCA; Flavio ;   et al. | 2018-12-20 |
Anti-cancer Combination Therapy App 20180346559 - Hilberg; Frank ;   et al. | 2018-12-06 |
Combination Treatment Of Cancer Comprising Egfr/her2 Inhibitors App 20180086744 - SOLCA; Flavio ;   et al. | 2018-03-29 |
Method For Egfr Directed Combination Treatment Of Cancer App 20170312360 - DENIS; Louis Jean ;   et al. | 2017-11-02 |
Quinazoline Derivatives For The Treatment Of Cancer Diseases App 20170112835 - SOLCA; Flavio ;   et al. | 2017-04-27 |
Anticancer Combination Therapy App 20170088609 - SOLCA; Flavio ;   et al. | 2017-03-30 |
Quinazoline derivatives for the treatment of cancer diseases Grant 9,539,258 - Solca , et al. January 10, 2 | 2017-01-10 |
Method For Egfr Directed Combination Treatment Of Cancer App 20160101175 - DENIS; Louis ;   et al. | 2016-04-14 |
Quinazoline Derivatives For The Treatment Of Cancer Diseases App 20150272954 - SOLCA; Flavio ;   et al. | 2015-10-01 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells, Or Angiogenesis App 20150265610 - STEFANIC; Martin Friedrich ;   et al. | 2015-09-24 |
Quinazoline derivatives for the treatment of cancer diseases Grant 9,089,571 - Solca , et al. July 28, 2 | 2015-07-28 |
Method For Egfr Directed Combination Treatment Of Cancer App 20140341926 - DENIS; Louis ;   et al. | 2014-11-20 |
Method for treating cancer harboring EGFR mutations Grant 8,877,764 - Solca November 4, 2 | 2014-11-04 |
Method for EGFR directed combination treatment of non-small cell lung cancer Grant 8,828,391 - Denis , et al. September 9, 2 | 2014-09-09 |
Combination Treatment Of Cancer Comprising Egfr/her2 Inhibitors App 20140199298 - SOLCA; Flavio ;   et al. | 2014-07-17 |
Anticancer Therapy App 20140194442 - Solca; Flavio ;   et al. | 2014-07-10 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them Grant 8,722,694 - Himmelsbach , et al. May 13, 2 | 2014-05-13 |
Combination Therapy In Treatment Of Cancer And Fibrotic Diseases App 20140066456 - VAN RYN; Joanne ;   et al. | 2014-03-06 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells, Or Angiogenesis App 20140057898 - STEFANIC; Martin Friedrich ;   et al. | 2014-02-27 |
Compounds Grant 8,623,887 - Zahn , et al. January 7, 2 | 2014-01-07 |
Quinazoline derivatives and pharmaceutical compositions containing them Grant 8,586,608 - Himmelsbach , et al. November 19, 2 | 2013-11-19 |
Combination therapy in treatment of oncological and fibrotic diseases App 20130289014 - SOLCA; Flavio ;   et al. | 2013-10-31 |
2,4-diamino-pyrimidines As Aurora Inhibitors App 20130281429 - ZAHN; Stephan Karl ;   et al. | 2013-10-24 |
Quinazoline Derivatives For The Treatment Of Cancer Diseases App 20130178487 - SOLCA; Flavio ;   et al. | 2013-07-11 |
Quinazoline derivatives for the treatment of cancer diseases Grant 8,404,697 - Solca , et al. March 26, 2 | 2013-03-26 |
Bibw 2992 For Use In The Treatment Of Triple Negative Breast Cancer App 20130012465 - Haslinger; Christian ;   et al. | 2013-01-10 |
Anticancer Therapy App 20130004481 - Solca; Flavio ;   et al. | 2013-01-03 |
Bicyclic heterocyclic compounds pharmaceutical compositions containing these compounds, their use and process for preparing the same Grant 8,343,982 - Himmelsbach , et al. January 1, 2 | 2013-01-01 |
Bicyclic Heterocycles, Pharmaceutical Compositions Containing These Compounds, Their Use And Processes For Preparing Them App 20120329778 - HIMMELSBACH; Frank ;   et al. | 2012-12-27 |
Method For Egfr Directed Combination Treatment Of Cancer App 20120294867 - DENIS; Louis ;   et al. | 2012-11-22 |
Substituted indolines as tyrosine kinase inhibitors Grant 8,207,179 - Engelhardt , et al. June 26, 2 | 2012-06-26 |
Method For Treating Colorectal Cancer App 20120157472 - Larsen; Annette ;   et al. | 2012-06-21 |
New Combination Therapy In Treatment Of Cancer And Fibrotic Diseases App 20120136004 - Van Ryn; Joanne ;   et al. | 2012-05-31 |
Quinazoline derivatives and pharmaceutical compositions containing them Grant RE43,431 - Himmelsbach , et al. May 29, 2 | 2012-05-29 |
Combination therapy in treatment of oncological and fibrotic diseases App 20120107304 - Solca; Flavio ;   et al. | 2012-05-03 |
2,4-diamino-pyrimidines As Aurora Inhibitors App 20110251174 - ZAHN; Stephan Karl ;   et al. | 2011-10-13 |
Dihydropteridinone compounds Grant 8,003,786 - Hoffmann , et al. August 23, 2 | 2011-08-23 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells, Or Angiogenesis App 20110171289 - STEFANIC; Martin Friedrich ;   et al. | 2011-07-14 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells, Or Angiogenesis App 20110136826 - HILBERG; Frank ;   et al. | 2011-06-09 |
Pyrimidines as PLK inhibitors App 20110086842 - STADTMUELLER; Heinz ;   et al. | 2011-04-14 |
Bicyclic Heterocyclic Compounds Pharmaceutical Compositions Containing These Compounds, Their Use And Process For Preparing The Same App 20110077246 - HIMMELSBACH; Frank ;   et al. | 2011-03-31 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them Grant 7,910,731 - Himmelsbach , et al. March 22, 2 | 2011-03-22 |
Methods Of Treating Diseases Using Quinazoline Derivatives And Pharmaceutical Compositions Containing Them App 20110046168 - HIMMELSBACH; Frank ;   et al. | 2011-02-24 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells, Or Angiogenesis App 20110039863 - HILBERG; Frank ;   et al. | 2011-02-17 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof Grant 7,863,281 - Himmelsbach , et al. January 4, 2 | 2011-01-04 |
Dihydropteridinone Compounds App 20100324288 - HOFFMANN; Matthias ;   et al. | 2010-12-23 |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis Grant 7,846,936 - Hilberg , et al. December 7, 2 | 2010-12-07 |
New Compounds App 20100222331 - Engelhardt; Harald ;   et al. | 2010-09-02 |
Methods for treating diseases or conditions using dihydropteridinone compounds Grant 7,786,299 - Hoffmann , et al. August 31, 2 | 2010-08-31 |
2-benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments Grant 7,759,347 - Hoffmann , et al. July 20, 2 | 2010-07-20 |
Intermediate compounds for making dihydropteridinones useful as pharmaceutical compositions and processes of making the same Grant 7,750,152 - Hoffman , et al. July 6, 2 | 2010-07-06 |
Compounds App 20100144706 - Zahn; Stephan Karl ;   et al. | 2010-06-10 |
Bicyclic Heterocycles, Pharmaceutical Compositions Containing These Compounds, Their Use And Processes For Preparing Them App 20100069414 - HIMMELSBACH; Frank ;   et al. | 2010-03-18 |
Quinazoline Derivatives And Pharmaceutical Compositions Containing Them App 20100010023 - HIMMELSBACH; Frank ;   et al. | 2010-01-14 |
Method For Treating Cancer Harboring Egfr Mutations App 20090318480 - Solca; Flavio | 2009-12-24 |
Combination Treatment Of Cancer Comprising Egfr/her2 Inhibitors App 20090306101 - Solca; Flavio ;   et al. | 2009-12-10 |
Quinazoline Derivatives For The Treatment Of Cancer Diseases App 20090306044 - Solca; Flavio ;   et al. | 2009-12-10 |
Bicyclic Heterocycles, Pharmaceutical Compositions Containing Them, Their Use, And Processes For Preparing Them App 20090203683 - HIMMELSBACH; Frank ;   et al. | 2009-08-13 |
2,4-diaminopyrimidines useful for treating cell proliferation diseases Grant 7,569,561 - Stadtmueller , et al. August 4, 2 | 2009-08-04 |
Pyrimidines as PLK inhibitors App 20090163465 - STADTMUELLER; Heinz ;   et al. | 2009-06-25 |
New compounds App 20090163467 - Zahn; Stephan Karl ;   et al. | 2009-06-25 |
Pyrimidines as PLK inhibitors App 20090149438 - STADTMUELLER; Heinz ;   et al. | 2009-06-11 |
2-benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments App 20090124628 - HOFFMANN; Matthias ;   et al. | 2009-05-14 |
Pyrimidines as PLK inhibitors Grant 7,521,457 - Stadtmueller , et al. April 21, 2 | 2009-04-21 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them App 20090036676 - Himmelsbach; Frank ;   et al. | 2009-02-05 |
New dihydropteridione derivatives, process for their manufacture and their use as medicament App 20080319190 - GRAUERT; Matthias ;   et al. | 2008-12-25 |
New dihydropteridione derivatives, process for their manufacture and their use as medicament App 20080319192 - GRAUERT; Matthias ;   et al. | 2008-12-25 |
New dihydropteridione derivatives, process for their manufacture and their use as medicament App 20080319193 - GRAUERT; Matthias ;   et al. | 2008-12-25 |
Piperazinyl Compounds App 20080293944 - Hoffmann; Matthias ;   et al. | 2008-11-27 |
Combinations For The Treatment Of Diseases Involving Cell Proliferation, Migration Or Apoptosis Of Myeloma Cells Or Angiogenesis App 20080254040 - STEFANIC; Martin Friedrich ;   et al. | 2008-10-16 |
Dihydropteridione derivatives, process for their manufacture and their use as medicament Grant 7,414,053 - Grauert , et al. August 19, 2 | 2008-08-19 |
Intermediate Compounds for making Dihydropteridinones Useful as Pharmaceutical Compositions App 20080171747 - Hoffman; Matthias ;   et al. | 2008-07-17 |
Bicyclic Heterocycles, Pharmaceutical Compositions Containing These Compounds, Their Use And Processes For The Preparation Thereof App 20080103161 - Himmelsbach; Frank ;   et al. | 2008-05-01 |
Dihydropteridione derivatives, process for their manufacture and their use as medicament Grant 7,332,491 - Grauert , et al. February 19, 2 | 2008-02-19 |
New Compounds App 20070207999 - Stadtmueller; Heinz ;   et al. | 2007-09-06 |
Bicyclic Heterocycles, Pharmaceutical Compositions Containing These Compounds, Their Use and Processes for Preparing Them App 20070185091 - Himmelsbach; Frank ;   et al. | 2007-08-09 |
Bicyclic heterocylces, pharmaceutical compositions containing these compounds, their use and processes for preparing them App 20070185081 - HIMMELSBACH; Frank ;   et al. | 2007-08-09 |
6-formyl-tetrahydropteridines, process for their manufacture and use thereof as medicaments Grant 7,241,889 - Hoffmann , et al. July 10, 2 | 2007-07-10 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them Grant 7,223,749 - Himmelsbach , et al. May 29, 2 | 2007-05-29 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them Grant 7,220,750 - Himmelsbach , et al. May 22, 2 | 2007-05-22 |
2,4-diamino-pyrimidines as aurora inhibitors App 20070032514 - Zahn; Stephan Karl ;   et al. | 2007-02-08 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them App 20060270672 - Himmelsbach; Frank ;   et al. | 2006-11-30 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them Grant 7,119,084 - Himmelsbach , et al. October 10, 2 | 2006-10-10 |
Pyrimidines as PLK inhibitors App 20060148800 - Stadtmueller; Heinz ;   et al. | 2006-07-06 |
Quinazoline derivatives and pharmaceutical compositions containing them App 20060100223 - Himmelsbach; Frank ;   et al. | 2006-05-11 |
Quinazoline derivatives and pharmaceutical compositions containing them Grant 7,019,012 - Himmelsbach , et al. March 28, 2 | 2006-03-28 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them App 20060063752 - Himmelsbach; Frank ;   et al. | 2006-03-23 |
New dihydropteridione derivatives, process for their manufacture and their use as medicament App 20060052383 - Grauert; Matthias ;   et al. | 2006-03-09 |
New dihydropteridione derivatives, process for their manufacture and their use as medicament App 20060046989 - Grauert; Matthias ;   et al. | 2006-03-02 |
Methods for treating diseases or conditions using dihydropteridinone compounds App 20060025411 - Hoffmann; Matthias ;   et al. | 2006-02-02 |
New 6-formyl-tetrahydropteridines, process for their manufacture and use thereof as medicaments App 20060014751 - Hoffmann; Matthias ;   et al. | 2006-01-19 |
2-Benzylaminodihydropteridinones, process for their manufacture and use thereof as medicaments App 20060004014 - Hoffmann; Matthias ;   et al. | 2006-01-05 |
4-amino-quinazoline and quinoline derivatives having an inhibitory effect on signal transduction mediated by tyrosine kinases Grant 6,972,288 - Himmelsbach , et al. December 6, 2 | 2005-12-06 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them App 20050182043 - Himmelsbach, Frank ;   et al. | 2005-08-18 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them Grant 6,924,285 - Himmelsbach , et al. August 2, 2 | 2005-08-02 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof App 20050159436 - Himmelsbach, Frank ;   et al. | 2005-07-21 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them App 20050107358 - Himmelsbach, Frank ;   et al. | 2005-05-19 |
Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions Grant 6,861,422 - Hoffmann , et al. March 1, 2 | 2005-03-01 |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis App 20050043233 - Stefanic, Martin Friedrich ;   et al. | 2005-02-24 |
Intermediate compounds for making dihydropteridinones useful as pharmaceutical compositions App 20050014761 - Hoffmann, Matthias ;   et al. | 2005-01-20 |
Methods of treating diseases or conditions using dihydropteridinone compounds App 20050014760 - Hoffmann, Matthias ;   et al. | 2005-01-20 |
New dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions App 20040176380 - Hoffmann, Matthias ;   et al. | 2004-09-09 |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases Grant 6,740,651 - Himmelsbach , et al. May 25, 2 | 2004-05-25 |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them App 20040048880 - Himmelsbach, Frank ;   et al. | 2004-03-11 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for the preparation thereof App 20040044014 - Himmelsbach, Frank ;   et al. | 2004-03-04 |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases Grant 6,656,946 - Himmelsbach , et al. December 2, 2 | 2003-12-02 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them Grant 6,653,305 - Himmelsbach , et al. November 25, 2 | 2003-11-25 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them Grant 6,627,634 - Himmelsbach , et al. September 30, 2 | 2003-09-30 |
Aminoquinazolines and their use as medicaments Grant 6,617,329 - Himmelsbach , et al. September 9, 2 | 2003-09-09 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them App 20020177601 - Himmelsbach, Frank ;   et al. | 2002-11-28 |
Quinazoline derivatives and phamaceutical compositions containing them App 20020173509 - Himmelsbach, Frank ;   et al. | 2002-11-21 |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them App 20020169180 - Himmelsbach, Frank ;   et al. | 2002-11-14 |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases App 20020115675 - Himmelsbach, Frank ;   et al. | 2002-08-22 |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases App 20020082271 - Himmelsbach, Frank ;   et al. | 2002-06-27 |
Aminoquinazolines which inhibit signal transduction mediated by tyrosine kinases App 20020082270 - Himmelsbach, Frank ;   et al. | 2002-06-27 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them App 20020077330 - Himmelsbach, Frank ;   et al. | 2002-06-20 |
Quinazolines, pharmaceutical compositions containing these compounds, their use and processes for preparing them Grant 6,403,580 - Himmelsbach , et al. June 11, 2 | 2002-06-11 |
Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them App 20010044435 - Himmelsbach, Frank ;   et al. | 2001-11-22 |