SHEPARD; H. Michael

Patent Applications and Registrations

Patent applications and USPTO patent grants for SHEPARD; H. Michael.The latest application filed is for "methods and compositions to treat autoimmune diseases and cancer".

Company Profile

4.38.64

SHEPARD; H. Michael - Springfield OR
Shepard; H. Michael - San Diego CA
Shepard; H. Michael - San Francisco CA
Shepard; H. Michael - Encinitas CA
Shepard; H. Michael - Rancho Sante Fe CA
Shepard; H. Michael - Rancho Santa Fe CA
Shepard; H. Michael - US
Shepard; H. Michael - Santa Fe CA

*profile and listings may contain filings by different individuals or companies with the same name. Review application materials to confirm ownership/assignment.

Patent Activity

Patent	Date
Methods And Compositions To Treat Autoimmune Diseases And Cancer App 20220288226 - SHEPARD; H. Michael	2022-09-15
Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor Grant 11,414,489 - Rosengren , et al. August 16, 2	2022-08-16
Antibodies And Enonomers App 20220175945 - SHEPARD; H. Michael	2022-06-09
Ph20 Polypeptide Variants, Formulations And Uses Thereof App 20210284985 - Wei; Ge ; et al.	2021-09-16
Ph20 Polypeptide Variants, Formulations And Uses Thereof App 20210277376 - Wei; Ge ; et al.	2021-09-09
PH20 polypeptide variants, formulations and uses thereof Grant 11,066,656 - Wei , et al. July 20, 2	2021-07-20
PH20 polypeptide variants, formulations and uses thereof Grant 11,041,149 - Wei , et al. June 22, 2	2021-06-22
PH20 polypeptide variants, formulations and uses thereof Grant 10,865,400 - Wei , et al. December 15, 2	2020-12-15
Ph20 Polypeptide Variants, Formulations And Uses Thereof App 20200318091 - WEI; GE ; et al.	2020-10-08
Ph20 Polypeptide Variants, Formulations And Uses Thereof App 20200255814 - WEI; Ge ; et al.	2020-08-13
Combination Therapy With An Anti-hyaluronan Agent And Therapeutic Agent App 20190083449 - Maneval; Daniel C. ; et al.	2019-03-21
Combination therapy with an anti-hyaluronan agent and therapeutic agent Grant 10,137,104 - Maneval , et al. November 27, 2	2018-11-27
Compositions Of Adenosine Deaminase-2 (ada2), Variants Thereof And Methods Of Using Same App 20180216095 - THANOS; Christopher D. ; et al.	2018-08-02
Compositions of adenosine deaminase-2 (ADA2), variants thereof and methods of using same Grant 9,969,998 - Thanos , et al. May 15, 2	2018-05-15
Combination therapy with an anti-hyaluronan agent and therapeutic agent Grant 9,913,822 - Maneval , et al. March 13, 2	2018-03-13
Combination Therapy With A Hyaluronan-degrading Enzyme And An Immune Checkpoint Inhibitor App 20180044419 - ROSENGREN; Sanna ; et al.	2018-02-15
Combination Therapy With An Anti-hyaluronan Agent And Therapeutic Agent App 20170290796 - Maneval; Daniel C. ; et al.	2017-10-12
Combination Therapy With A Hyaluronan-degrading Enzyme And An Immune Checkpoint Inhibitor App 20170218069 - ROSENGREN; Sanna ; et al.	2017-08-03
Compositions Of Adenosine Deaminase-2 (ada2), Variants Thereof And Methods Of Using Same App 20170166878 - Thanos; Christopher D. ; et al.	2017-06-15
Ph20 Polypeptide Variants, Formulations And Uses Thereof App 20160362670 - Wei; Ge ; et al.	2016-12-15
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof Grant 9,458,442 - Jiang , et al. October 4, 2	2016-10-04
Compositions Of Adenosine Deaminase-2 (ada2), Variants Thereof And Methods Of Using Same App 20160272960 - Thanos; Christopher D. ; et al.	2016-09-22
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods Grant 9,278,124 - Shepard , et al. March 8, 2	2016-03-08
Companion Diagnostic For Anti-hyaluronan Agent Therapy And Methods Of Use Thereof App 20150218544 - Jiang; Ping ; et al.	2015-08-06
Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof App 20150196625 - Paladini; Rudolph D. ; et al.	2015-07-16
Modified Anti-epidermal Growth Factor Receptor Antibodies And Methods Of Use Thereof App 20150071923 - Wei; Ge ; et al.	2015-03-12
Companion Diagnostic For Anti-hyaluronan Agent Therapy And Methods Of Use Thereof App 20140348817 - Jiang; Ping ; et al.	2014-11-27
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof Grant 8,846,034 - Jiang , et al. September 30, 2	2014-09-30
Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof App 20140219992 - Paladini; Rudolph D. ; et al.	2014-08-07
PH20 Polypeptide Variants, Formulations And Uses Thereof App 20140178330 - Wei; Ge ; et al.	2014-06-26
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof App 20140170159 - Wei; Ge ; et al.	2014-06-19
Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods App 20140105824 - Shepard; H. Michael ; et al.	2014-04-17
Combination therapy with an anti-hyaluronan agent and therapeutic agent App 20130302400 - Maneval; Daniel C. ; et al.	2013-11-14
PH20 Polypeptide Variants, Formulations And Uses Thereof App 20130302275 - Wei; Ge ; et al.	2013-11-14
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof App 20130266579 - Wei; Ge ; et al.	2013-10-10
Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof App 20130202583 - Jiang; Ping ; et al.	2013-08-08
Compositions Comprising Optimized Her1 And Her3 Multimers And Methods Of Use Thereof App 20100278801 - Shepard; H. Michael ; et al.	2010-11-04
Pan-cell Surface Receptor-specific Therapeutics App 20100055093 - Shepard; H. Michael ; et al.	2010-03-04
Enzyme catalyzed therapeutic compounds Grant 7,605,144 - Shepard , et al. October 20, 2	2009-10-20
Enzyme catalyzed therapeutic agents Grant 7,601,703 - Shepard , et al. October 13, 2	2009-10-13
Cell Surface Receptor Isoforms And Methods Of Identifying And Using The Same App 20090170769 - JIN; Pei ; et al.	2009-07-02
Novel Phosphoramidate Compounds And Methods Of Use App 20090069268 - SHEPARD; H. MICHAEL ; et al.	2009-03-12
Methods and compositions for overcoming resistance to biologic and chemotherapy Grant 7,465,734 - Shepard December 16, 2	2008-12-16
Phosphoramidate compounds and methods of use Grant 7,462,605 - Shepard , et al. December 9, 2	2008-12-09
Method For Selectively Transducing Pathologic Mammalian Cells Using A Tumor Suppressor Gene App 20080286247 - Shepard; H. Michael ; et al.	2008-11-20
Methods for treating therapy-resistant tumors Grant 7,419,968 - Shepard September 2, 2	2008-09-02
Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene App 20070237753 - Shepard; H. Michael ; et al.	2007-10-11
Methods to treat autoimmune and inflammatory conditions App 20070213307 - Shepard; H. Michael	2007-09-13
Methods for production of receptor and ligand isoforms App 20070166788 - Jin; Pei ; et al.	2007-07-19
Hepatocyte growth factor intron fusion proteins App 20070161081 - Jin; Pei ; et al.	2007-07-12
Use Of Bvdu For Inhibiting The Growth Of Hyperproliferative Cells App 20070155673 - Boyer; Christopher ; et al.	2007-07-05
Isoforms of receptor for advanced glycation end products (RAGE) and methods of identifying and using same App 20070087406 - Jin; Pei ; et al.	2007-04-19
Cell surface receptor isoforms and methods of identifying and using the same App 20060286102 - Jin; Pei ; et al.	2006-12-21
Methods to treat autoimmune and inflammatory conditions Grant 7,138,388 - Shepard November 21, 2	2006-11-21
Method of using an adenoviral vector encoding a retinoblastoma protein to treat hyperproliferating cells Grant 7,105,156 - Lee , et al. September 12, 2	2006-09-12
Intron fusion proteins, and methods of identifying and using same App 20050239088 - Shepard, H. Michael ; et al.	2005-10-27
Compositions and methods for treating cells having double minute DNA Grant 6,946,259 - Wahl , et al. September 20, 2	2005-09-20
Methods and compositions for overcoming resistance to biologic and chemotherapy App 20050123983 - Shepard, H. Michael	2005-06-09
Compositions And Methods For Treating Cells Having Double Minute Dna App 20050123909 - WAHL, GEOFFREY M. ; et al.	2005-06-09
Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene App 20050079163 - Shepard, H. Michael ; et al.	2005-04-14
Enzyme catalyzed therapeutic compounds App 20040077588 - Shepard, H. Michael ; et al.	2004-04-22
Enzyme catalyzed therapeutic activation Grant 6,683,061 - Shepard , et al. January 27, 2	2004-01-27
Methods for identifying therapeutic targets for treating infectious disease App 20030130179 - Shepard, H. Michael ; et al.	2003-07-10
Viral enzyme activated prototoxophores and use of same to treat viral infections App 20030114385 - Cathers, Brian E. ; et al.	2003-06-19
Novel phosphoramidate compounds and methods of use App 20030109697 - Shepard, H. Michael ; et al.	2003-06-12
Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene App 20030077250 - Shepard, H. Michael ; et al.	2003-04-24
Method of treating tumor cells by inhibiting growth factor receptor function App 20020192211 - Hudziak, Robert M. ; et al.	2002-12-19
Methods to treat autoimmune and inflammatory conditions App 20020151519 - Shepard, H. Michael	2002-10-17
Synergistic ECTA compositions App 20020147175 - Shepard, H. Michael ; et al.	2002-10-10
Monoclonal antibodies directed to the HER2 receptor Grant 6,399,063 - Hudziak , et al. June 4, 2	2002-06-04
Monoclonal antibodies directed to the HER2 receptor Grant 6,387,371 - Hudziak , et al. May 14, 2	2002-05-14
HER2 extracellular domain Grant 6,333,169 - Hudziak , et al. December 25, 2	2001-12-25
Enzyme catalyzed therapeutic agents App 20010034440 - Shepard, H. Michael ; et al.	2001-10-25
Methods and compositions for overcoming resistance to biologic and chemotherapy App 20010016329 - Shepard, H. Michael	2001-08-23
Enzyme catalyzed therapeutic agents Grant 6,245,750 - Shepard June 12, 2	2001-06-12
Monoclonal antibodies directed to the HER2 receptor Grant 6,165,464 - Hudziak , et al. December 26, 2	2000-12-26
Application of enzyme prodrugs as anti-infective agents Grant 6,159,706 - Shepard December 12, 2	2000-12-12
HER2 extracellular domain Grant 6,015,567 - Hudziak , et al. January 18, 2	2000-01-18
Therapeutic use of the retinoblastoma susceptibility gene product Grant 5,851,991 - Lee , et al. December 22, 1	1998-12-22
Method of purification of viral vectors Grant 5,837,520 - Shabram , et al. November 17, 1	1998-11-17
Monoclonal antibodies directed to the HER2 receptor Grant 5,772,997 - Hudziak , et al. June 30, 1	1998-06-30
Monoclonal antibodies directed to the her2 receptor Grant 5,770,195 - Hudziak , et al. June 23, 1	1998-06-23
Monoclonal antibodies directed to the HER2 receptor Grant 5,720,954 - Hudziak , et al. February 24, 1	1998-02-24
Monoclonal antibodies directed to the HER2 receptor Grant 5,677,171 - Hudziak , et al. October 14, 1	1997-10-14
Use of tumor necrosis factor (TNF) as an adjuvant Grant 4,963,354 - Shepard , et al. October 16, 1	1990-10-16
Method and compositions for modulating neovascularization Grant 4,808,402 - Leibovich , et al. February 28, 1	1989-02-28

Company Registrations

SEC

0001507433

Shepard H. Michael

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