Patent | Date |
---|
Antiproliferative compounds, and their pharmaceutical compositions and uses Grant 11,365,184 - Alexander , et al. June 21, 2 | 2022-06-21 |
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Grant 11,292,796 - Elsner , et al. April 5, 2 | 2022-04-05 |
Antiproliferative Compounds, And Their Pharmaceutical Compositions And Uses App 20210040063 - Alexander; Matthew D. ;   et al. | 2021-02-11 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20200262840 - ELSNER; Jan ;   et al. | 2020-08-20 |
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Grant 10,683,298 - Elsner , et al. | 2020-06-16 |
Antiproliferative compounds, and their pharmaceutical compositions and uses Grant 10,618,883 - Alexander , et al. | 2020-04-14 |
Antiproliferative Compounds, And Their Pharmaceutical Compositions And Uses App 20190152942 - Alexander; Matthew D. ;   et al. | 2019-05-23 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20190077806 - ELSNER; Jan ;   et al. | 2019-03-14 |
Antiproliferative compounds, and their pharmaceutical compositions and uses Grant 10,227,325 - Alexander , et al. | 2019-03-12 |
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Grant 10,167,290 - Elsner , et al. J | 2019-01-01 |
Antiproliferative Compounds, And Their Pharmaceutical Compositions And Uses App 20180186767 - Alexander; Matthew D. ;   et al. | 2018-07-05 |
Antiproliferative compounds, and their pharmaceutical compositions and uses Grant 9,938,254 - Alexander , et al. April 10, 2 | 2018-04-10 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20170342080 - ELSNER; Jan ;   et al. | 2017-11-30 |
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith Grant 9,783,505 - Papa , et al. October 10, 2 | 2017-10-10 |
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Grant 9,771,371 - Elsner , et al. September 26, 2 | 2017-09-26 |
Antiproliferative Compounds, And Their Pharmaceutical Compositions And Uses App 20170197933 - Alexander; Matthew D. ;   et al. | 2017-07-13 |
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith Grant 9,556,126 - Papa , et al. January 31, 2 | 2017-01-31 |
Substituted Diaminopyrimidyl Compounds, Compositions Thereof, And Methods Of Treatment Therewith App 20160354374 - Papa; Patrick ;   et al. | 2016-12-08 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20160024101 - ELSNER; Jan ;   et al. | 2016-01-28 |
Halogen substituted pyrazines as intermediates of mTOR kinase inhibitors Grant 9,193,692 - Perrin-Ninkovic , et al. November 24, 2 | 2015-11-24 |
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith Grant 9,156,798 - Bahmanyar , et al. October 13, 2 | 2015-10-13 |
Substituted Diaminopyrimidyl Compounds, Compositions Thereof, And Methods Of Treatment Therewith App 20150246890 - BAHMANYAR; Sogole ;   et al. | 2015-09-03 |
Methods of synthesis and purification of heteroaryl compounds Grant 9,079,900 - Harris , et al. July 14, 2 | 2015-07-14 |
Substituted Diaminopyrimidyl Compounds, Compositions Thereof, And Methods Of Treatment Therewith App 20150175557 - Papa; Patrick ;   et al. | 2015-06-25 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20150051397 - Perrin-Ninkovic; Sophie ;   et al. | 2015-02-19 |
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors Grant 8,907,087 - Perrin-Ninkovic , et al. December 9, 2 | 2014-12-09 |
Methods Of Synthesis And Purification Of Heteroaryl Compounds App 20140155593 - Harris; Roy L. ;   et al. | 2014-06-05 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20130289271 - Perrin-Ninkovic; Sophie ;   et al. | 2013-10-31 |
Methods of synthesis and purification of heteroaryl compounds Grant 8,569,494 - Harris , et al. October 29, 2 | 2013-10-29 |
Methods Of Synthesis And Purification Of Heteroaryl Compounds App 20130245254 - Harris; Roy L. ;   et al. | 2013-09-19 |
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/AKT pathway Grant 8,507,492 - Perrin-Ninkovic , et al. August 13, 2 | 2013-08-13 |
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway Grant 8,492,381 - Perrin-Ninkovic , et al. July 23, 2 | 2013-07-23 |
Aminotriazolopyridines, Compositions Thereof, And Methods Of Treatment Therewith App 20130005707 - Bahmanyar; Sogole ;   et al. | 2013-01-03 |
Aminotriazolopyridines, compositions thereof, and methods of treatment therewith Grant 8,299,056 - Bahmanyar , et al. October 30, 2 | 2012-10-30 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITOR FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20120071658 - Perrin-Ninkovic; Sophie ;   et al. | 2012-03-22 |
PYRAZINO[2,3-b]PYRAZINE mTOR KINASE INHIBITOR FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20120059164 - Perrin-Ninkovic; Sophie ;   et al. | 2012-03-08 |
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway Grant 8,110,578 - Perrin-Ninkovic , et al. February 7, 2 | 2012-02-07 |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith Grant 8,101,588 - Albers , et al. January 24, 2 | 2012-01-24 |
Methods Of Synthesis And Purification Of Heteroaryl Compounds App 20110137028 - Harris; Roy L. ;   et al. | 2011-06-09 |
mTOR KINASE INHIBITORS FOR ONCOLOGY INDICATIONS AND DISEASES ASSOCIATED WITH THE mTOR/PI3K/AKT PATHWAY App 20100216781 - Perrin-Ninkovic; Sophie ;   et al. | 2010-08-26 |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith Grant 7,723,340 - Albers , et al. May 25, 2 | 2010-05-25 |
Aminotriazolopyridines, Compositions Thereof, And Methods Of Treatment Therewith App 20100093698 - Bahmanyar; Sogole ;   et al. | 2010-04-15 |
Methods Of Treatment Comprising The Administration Of Haloaryl Substituted Aminopurines Or Compositions Thereof App 20090312320 - Albers; Ronald J. ;   et al. | 2009-12-17 |
Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith App 20090275564 - Albers; Ronald J. ;   et al. | 2009-11-05 |
Indazole Compounds And Methods Of Use Thereof App 20090099178 - Bhagwat; Shripad S. ;   et al. | 2009-04-16 |
Methods of using indazole derivatives as JNK inhibitors Grant 7,220,771 - Bhagwat , et al. May 22, 2 | 2007-05-22 |
Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith Grant 7,211,594 - Bhagwat , et al. May 1, 2 | 2007-05-01 |
Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith Grant 7,208,513 - Bhagwat , et al. April 24, 2 | 2007-04-24 |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith App 20070060598 - Albers; Ronald J. ;   et al. | 2007-03-15 |
Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith App 20060287344 - Albers; Ronald J. ;   et al. | 2006-12-21 |
Indazole compounds and methods of use thereof App 20060004043 - Bhagwat; Shripad S. ;   et al. | 2006-01-05 |
Indazole derivatives as JNK inhibitors and compositions and methods related thereto Grant 6,897,231 - Bhagwat , et al. May 24, 2 | 2005-05-24 |
Indazole derivatives as JNK inhibitors and compositions and methods related thereto App 20050107457 - Bhagwat, Shripad S. ;   et al. | 2005-05-19 |
Indazole compounds, compositions thereof and methods of treatment therewith App 20050009876 - Bhagwat, Shripad S. ;   et al. | 2005-01-13 |
Methods for treating an inflammatory condition or inhibiting JNK App 20040127536 - Bhagwat, Shripad S. ;   et al. | 2004-07-01 |
Indazole derivatives as JNK inhibitors and compositions and methods related thereto App 20040077877 - Bhagwat, Shripad S. ;   et al. | 2004-04-22 |
Indazole derivatives as JNK inhibitors and compositions and methods related thereto App 20020103229 - Bhagwat, Shripad S. ;   et al. | 2002-08-01 |