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Macrocycles as factor XIA inhibitors Grant 11,136,327 - Corte , et al. October 5, 2 | 2021-10-05 |
Lactam, cyclic urea and carbamate, and triazolone derivatives as potent and selective rock inhibitors Grant 10,730,858 - Hu , et al. | 2020-08-04 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20200140436 - Pinto; Donald J.P. ;   et al. | 2020-05-07 |
Macrocycles As Factor Xia Inhibitors App 20200087312 - Corte; James R. ;   et al. | 2020-03-19 |
Macrocycles as factor XIa inhibitors Grant 10,487,086 - Corte , et al. Nov | 2019-11-26 |
Lactam, Cyclic Urea And Carbamate, And Triazolone Derivatives As Potent And Selective Rock Inhibitors App 20190300510 - Hu; Zilun ;   et al. | 2019-10-03 |
Phthalazinones and isoquinolinones as rock inhibitors Grant 10,385,026 - Glunz , et al. A | 2019-08-20 |
Five-membered heterocycles useful as serine protease inhibitors Grant 10,112,936 - Hangeland , et al. October 30, 2 | 2018-10-30 |
Tied-back benzamide derivatives as potent rock inhibitors Grant 10,112,939 - Hu , et al. October 30, 2 | 2018-10-30 |
Diamide macrocycles that are FXIa inhibitors Grant 10,081,623 - Shi , et al. September 25, 2 | 2018-09-25 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20180244673 - Pinto; Donald J.P. ;   et al. | 2018-08-30 |
Phthalazinones And Isoquinolinones As Rock Inhibitors App 20180162823 - Glunz; Peter W. ;   et al. | 2018-06-14 |
Phthalazinones and isoquinolinones as rock inhibitors Grant 9,926,282 - Glunz , et al. March 27, 2 | 2018-03-27 |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors Grant 9,914,740 - Quan , et al. March 13, 2 | 2018-03-13 |
Macrocycles As Factor Xia Inhibitors App 20180022753 - Corte; James R. ;   et al. | 2018-01-25 |
Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors Grant 9,828,345 - Hu , et al. November 28, 2 | 2017-11-28 |
Macrocycles as factor XIa inhibitors Grant 9,802,939 - Corte , et al. October 31, 2 | 2017-10-31 |
Diamide Macrocycles That Are Fxia Inhibitors App 20170283403 - Shi; Jun ;   et al. | 2017-10-05 |
Macrocycles as factor XIa inhibitors Grant 9,745,313 - Quan , et al. August 29, 2 | 2017-08-29 |
Tied-back Benzamide Derivatives As Potent Rock Inhibitors App 20170226105 - Hu; Zilun ;   et al. | 2017-08-10 |
Five-membered Heterocycles Useful As Serine Protease Inhibitors App 20170166560 - Hangeland; Jon J. ;   et al. | 2017-06-15 |
Tricyclic pyrido-carboxamide derivatives as rock inhibitors Grant 9,663,529 - Quan , et al. May 30, 2 | 2017-05-30 |
Five-membered heterocycles useful as serine protease inhibitors Grant 9,617,224 - Hangeland , et al. April 11, 2 | 2017-04-11 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20170050964 - Pinto; Donald J.P. ;   et al. | 2017-02-23 |
Macrocycles As Factor Xia Inhibitors App 20160362414 - Quan; Mimi L. ;   et al. | 2016-12-15 |
Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors Grant 9,458,110 - Quan , et al. October 4, 2 | 2016-10-04 |
Macrocycles as factor XIa inhibitors Grant 9,453,029 - Quan , et al. September 27, 2 | 2016-09-27 |
Tricyclic Pyrido-carboxamide Derivatives As Rock Inhibitors App 20160152627 - Quan; Mimi L. ;   et al. | 2016-06-02 |
Tricyclic Pyrido-carboxamide Derivatives As Rock Inhibitors App 20160152628 - Quan; Mimi L. ;   et al. | 2016-06-02 |
Phthalazinones And Isoquinolinones As Rock Inhibitors App 20160090364 - Glunz; Peter W. ;   et al. | 2016-03-31 |
Phenylpyrazole Derivatives As Potent Rock1 And Rock2 Inhibitors App 20160016910 - Quan; Mimi L. ;   et al. | 2016-01-21 |
Phenylpyrazole Derivatives As Potent Rock1 And Rock2 Inhibitors App 20160002172 - Hu; Zilun ;   et al. | 2016-01-07 |
Substituted phthalazinones as rock inhibitors Grant 9,221,767 - Glunz , et al. December 29, 2 | 2015-12-29 |
Macrocycles As Factor Xia Inhibitors App 20150266894 - Quan; Mimi L. ;   et al. | 2015-09-24 |
Five-membered Heterocycles Useful As Serine Protease Inhibitors App 20150259297 - Hangeland; Jon J. ;   et al. | 2015-09-17 |
Phenylpyrazole derivatives as potent ROCK1 and ROCK2 inhibitors Grant 9,126,944 - Quan , et al. September 8, 2 | 2015-09-08 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20150210691 - Pinto; Donald J.P. ;   et al. | 2015-07-30 |
Macrocycles as factor XIa inhibitors Grant 9,079,918 - Quan , et al. July 14, 2 | 2015-07-14 |
Five-membered heterocycles useful as serine protease inhibitors Grant 9,079,860 - Hangeland , et al. July 14, 2 | 2015-07-14 |
Macrocycles As Factor Xia Inhibitors App 20150112058 - Corte; James R. ;   et al. | 2015-04-23 |
Macrocycles as factor XIa inhibitors Grant 8,940,720 - Corte , et al. January 27, 2 | 2015-01-27 |
Macrocycles As Factor Xia Inhibitors App 20140343276 - Quan; Mimi L. ;   et al. | 2014-11-20 |
Macrocycles as factor XIa inhibitors Grant 8,828,983 - Quan , et al. September 9, 2 | 2014-09-09 |
Phenylpyrazole Derivatives As Potent Rock1 And Rock2 Inhibitors App 20140243338 - Quan; Mimi L. ;   et al. | 2014-08-28 |
Five-membered Heterocycles Useful As Serine Protease Inhibitors App 20140206706 - Hangeland; Jon J. ;   et al. | 2014-07-24 |
Phthalazinones And Isoquinolinones As Rock Inhibitors App 20140206686 - Glunz; Peter W. ;   et al. | 2014-07-24 |
Five-membered heterocycles useful as serine protease inhibitors Grant 8,716,492 - Hangeland , et al. May 6, 2 | 2014-05-06 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20140113892 - Pinto; Donald J.P. ;   et al. | 2014-04-24 |
Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIa inhibitors Grant 8,604,056 - Pinto , et al. December 10, 2 | 2013-12-10 |
Dipeptide analogs as coagulation factor inhibitors Grant 8,367,709 - Pinto , et al. February 5, 2 | 2013-02-05 |
Macrocycles As Factor Xia Inhibitors App 20120309960 - Quan; Mimi L. ;   et al. | 2012-12-06 |
Pyridazine derivatives as factor xia inhibitors Grant 8,324,199 - Corte , et al. December 4, 2 | 2012-12-04 |
Arylpropionamide, Arylacrylamide, Arylpropynamide, Or Arylmethylurea Analogs As Factor Xia Inhibitors App 20120270853 - Pinto; Donald J.P. ;   et al. | 2012-10-25 |
Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIa inhibitors Grant 8,252,830 - Pinto , et al. August 28, 2 | 2012-08-28 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20120201816 - Pinto; Donald J. P. ;   et al. | 2012-08-09 |
Five-membered Heterocycles Useful As Serine Protease Inhibitors App 20120088758 - Hangeland; Jon J. ;   et al. | 2012-04-12 |
Macrocycles As Factor Xia Inhibitors App 20120041190 - Corte; James R. ;   et al. | 2012-02-16 |
Five-membered heterocycles useful as serine protease inhibitors Grant 8,101,778 - Hangeland , et al. January 24, 2 | 2012-01-24 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20110212930 - Pinto; Donald J.P. ;   et al. | 2011-09-01 |
Arylpropionamide, Arylacrylamide, Arylpropynamide, Or Arylmethylurea Analogs As Factor Xia Inhibitors App 20110028446 - Pinto; Donald J.P. ;   et al. | 2011-02-03 |
Pyridazine Derivatives As Factor Xia Inhibitors App 20110021492 - Corte; James R. ;   et al. | 2011-01-27 |
Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIa inhibitors Grant 7,842,708 - Pinto , et al. November 30, 2 | 2010-11-30 |
Dipeptide Analogs As Coagulation Factor Inhibitors App 20100173899 - Pinto; Donald J.P. ;   et al. | 2010-07-08 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20100119510 - Pinto; Donald J.P. ;   et al. | 2010-05-13 |
Tetrahydroquinoline derivatives useful as serine protease inhibitors Grant 7,709,646 - Quan , et al. May 4, 2 | 2010-05-04 |
Arylpropionamide, Arylacrylamide, Arylpropynamide, Or Arylmethylurea Analogs As Factor Xia Inhibitors App 20100022506 - Pinto; Donald J.P. ;   et al. | 2010-01-28 |
Substituted biaryl compounds as factor XIa inhibitors Grant 7,645,799 - Corte , et al. January 12, 2 | 2010-01-12 |
Arylpropionamide, arylacrylamide, ayrlpropynamide, or arylmethylurea analogs as factor XIa inhibitors Grant 7,626,039 - Pinto , et al. December 1, 2 | 2009-12-01 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20090176758 - Pinto; Donald J.P. ;   et al. | 2009-07-09 |
Substituted Biaryl Compounds As Factor Xia Inhibitors App 20090062287 - Corte; James R. ;   et al. | 2009-03-05 |
Five-membered Heterocycles Useful As Serine Protease Inhibitors App 20090036438 - Hangeland; Jon J. ;   et al. | 2009-02-05 |
Substituted biaryl compounds as factor XIa inhibitors Grant 7,459,564 - Corte , et al. December 2, 2 | 2008-12-02 |
Five-membered heterocycles useful as serine protease inhibitors Grant 7,453,002 - Hangeland , et al. November 18, 2 | 2008-11-18 |
Arylpropionamide, Arylacrylamide, Arylpropynamide, Or Arylmethylurea Analogs As Factor Xia Inhibitors App 20080161373 - Pinto; Donald J.P. ;   et al. | 2008-07-03 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Grant 7,371,761 - Pinto , et al. May 13, 2 | 2008-05-13 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20080090807 - Pinto; Donald J. P. ;   et al. | 2008-04-17 |
Guanidine mimics as factor Xa inhibitors Grant 7,235,575 - Lam , et al. June 26, 2 | 2007-06-26 |
Lactam-containing Compounds And Derivatives Thereof As Factor Xa Inhibitors App 20070135426 - Pinto; Donald J.P. ;   et al. | 2007-06-14 |
Tetrahydroquinoline derivatives useful as serine protease inhibitors Grant 7,138,412 - Quan , et al. November 21, 2 | 2006-11-21 |
Biarylmethyl indolines and indoles as antithromboembolic agents Grant 7,129,264 - Smallheer , et al. October 31, 2 | 2006-10-31 |
Substituted biaryl compounds as factor XIa inhibitors App 20060154915 - Corte; James R. ;   et al. | 2006-07-13 |
Novel guanidine mimics as factor Xa inhibitors App 20060040973 - Lam; Patrick Y. ;   et al. | 2006-02-23 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Grant 6,995,172 - Pinto , et al. February 7, 2 | 2006-02-07 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Grant 6,989,391 - Pinto , et al. January 24, 2 | 2006-01-24 |
Five-membered heterocycles useful as serine protease inhibitors App 20050282805 - Hangeland, Jon J. ;   et al. | 2005-12-22 |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors App 20050267097 - Pinto, Donald J.P. ;   et al. | 2005-12-01 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors App 20050261287 - Pinto, Donald J.P. ;   et al. | 2005-11-24 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors Grant 6,967,208 - Pinto , et al. November 22, 2 | 2005-11-22 |
Intermediates for guanidine mimics as factor Xa inhibitors Grant 6,965,036 - Quan , et al. November 15, 2 | 2005-11-15 |
Guanidine mimics factor Xa inhibitors Grant 6,958,356 - Lam , et al. October 25, 2 | 2005-10-25 |
Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors Grant 6,951,872 - Jacobson , et al. October 4, 2 | 2005-10-04 |
Substituted amino methyl factor Xa inhibitors Grant 6,949,550 - Quan , et al. September 27, 2 | 2005-09-27 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors App 20050171085 - Pinto, Donald J.P. ;   et al. | 2005-08-04 |
Guanidine mimics as factor Xa inhibitors Grant 6,906,070 - Lam , et al. June 14, 2 | 2005-06-14 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors App 20050124602 - Pinto, Donald J.P. ;   et al. | 2005-06-09 |
Bicyclic inhibitors of factor Xa Grant 6,878,710 - Jacobson , et al. April 12, 2 | 2005-04-12 |
Nitrogen containing heterobicycles as factor Xa inhibitors Grant 6,858,616 - Fevig , et al. February 22, 2 | 2005-02-22 |
Tetrahydroquinoline derivatives useful as serine protease inhibitors App 20040235847 - Quan, Mimi L. ;   et al. | 2004-11-25 |
Biarylmethyl indolines, indoles and tetrahydroquinolines, useful as serine protease inhibitors App 20040220206 - Smallheer, Joanne M. ;   et al. | 2004-11-04 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors App 20040220174 - Pinto, Donald J.P. ;   et al. | 2004-11-04 |
Fused heterocyclic inhibitors of factor Xa Grant 6,790,845 - Jacobson , et al. September 14, 2 | 2004-09-14 |
Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors App 20040132718 - Jacobson, Irina C. ;   et al. | 2004-07-08 |
N-[4-(1H-imidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-c arboxamides as factor Xa inhibitors Grant 6,730,689 - Quan May 4, 2 | 2004-05-04 |
Nitrogen containing heterobicycles as factor Xa inhibitors Grant 6,716,841 - Jacobson , et al. April 6, 2 | 2004-04-06 |
Novel intermediates for guanidine mimics as factor Xa inhibitors App 20040063772 - Quan, Mimi L. ;   et al. | 2004-04-01 |
Substituted amino methyl factor Xa inhibitors App 20030212054 - Quan, Mimi L. ;   et al. | 2003-11-13 |
Lactam-containing compounds and derivatives thereof as factor Xa inhibitors App 20030191115 - Pinto, Donald J.P. ;   et al. | 2003-10-09 |
Inhibitors of factor Xa with a neutral P1 specificity group Grant 6,602,895 - Galemmo, Jr. , et al. August 5, 2 | 2003-08-05 |
Novel N-[4- (1H-imidazol-1-yl) -2-fluorophenyl ] -3- (trifluoromethyl) -1H-pyrazole-5-carboxamides as factor Xa inhibitors App 20030144287 - Quan, Mimi L. | 2003-07-31 |
Heteroaryl-phenyl substituted factor Xa inhibitors Grant 6,599,926 - Pinto , et al. July 29, 2 | 2003-07-29 |
Bicyclic inhibitors of factor Xa App 20030096804 - Jacobson, Irina C. ;   et al. | 2003-05-22 |
Nitrogen containing heterobicycles as factor Xa inhibitors App 20030096820 - Jacobson, Irina C. ;   et al. | 2003-05-22 |
Inhibitors of factor Xa with a neutral P1 specificity group App 20030092740 - Galemmo, Robert A. ;   et al. | 2003-05-15 |
Fused heterocyclic inhibitors of factor Xa App 20030087909 - Jacobson, Irina C. ;   et al. | 2003-05-08 |
Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa Grant 6,552,042 - Han , et al. April 22, 2 | 2003-04-22 |
Nitrogen containing heterobicycles as factor Xa inhibitors App 20030069237 - Fevig, John M. ;   et al. | 2003-04-10 |
Novel guanidine mimics factor Xa inhibitors App 20030069258 - Lam, Patrick Y. ;   et al. | 2003-04-10 |
Heteroaryl-phenyl heterobicyclic factor Xa inhibitors Grant 6,506,771 - Pinto , et al. January 14, 2 | 2003-01-14 |
Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors App 20020183324 - Jacobson, Irina C. ;   et al. | 2002-12-05 |
Heteroaryl- phenyl heterobicyclic factor Xa inhibitors App 20020119986 - Pinto, Donald J.P. ;   et al. | 2002-08-29 |
Nitrogen containing heterobicycles as factor Xa inhibitors Grant 6,429,205 - Jacobson , et al. August 6, 2 | 2002-08-06 |
Heteroaryl-phenyl substituted factor Xa inhibitors App 20020103202 - Pinto, Donald J.P. ;   et al. | 2002-08-01 |
Nitrogen containing heterobicycles as factor Xa inhibitors Grant 6,413,980 - Fevig , et al. July 2, 2 | 2002-07-02 |
Novel guanidine mimics as factor Xa inhibitors App 20020025963 - Lam, Patrick Y. ;   et al. | 2002-02-28 |
Thrombin or factor Xa inhibitors App 20020022614 - Pinto, Donald J.P. ;   et al. | 2002-02-21 |
Guanidine mimics as factor Xa inhibitors Grant 6,339,099 - Lam , et al. January 15, 2 | 2002-01-15 |
Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa App 20010021775 - Han, Qi ;   et al. | 2001-09-13 |
Benzimidazolinones, benzoxazolinones, benzopiperazinones, indanones, and derivatives thereof as inhibitors of factor Xa Grant 6,207,697 - Han , et al. March 27, 2 | 2001-03-27 |
Inhibitors of factor Xa with a neutral P1 specificity group Grant 5,998,424 - Galemmo, Jr. , et al. December 7, 1 | 1999-12-07 |
Angiotensin II receptor blocking imidazolinone derivatives Grant 5,512,681 - Boswell , et al. April 30, 1 | 1996-04-30 |
Imidazole 5-position substituted angiotensin II antagonists Grant 5,395,844 - Duncia , et al. March 7, 1 | 1995-03-07 |