loadpatents
Patent applications and USPTO patent grants for Penning; Thomas D..The latest application filed is for "macrocyclic mcl-1 inhibitors and methods of use".
Patent | Date |
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Macrocyclic MCL-1 Inhibitors and Methods of Use App 20200325153 - Judd; Andrew S. ;   et al. | 2020-10-15 |
Macrocyclic MCL-1 inhibitors and methods of use Grant 10,676,485 - Judd , et al. | 2020-06-09 |
Macrocyclic MCL-1 Inhibitors and Methods of Use App 20200010480 - Brady; Patrick B. ;   et al. | 2020-01-09 |
Macrocyclic MCL-1 inhibitors and methods of use App 20190144465 - Judd; Andrew S. ;   et al. | 2019-05-16 |
Macrocyclic MCL-1 inhibitors and methods of use App 20190055264 - Brady; Patrick B. ;   et al. | 2019-02-21 |
Spirocyclic Hat Inhibitors And Methods For Their Use App 20180193315 - Kesicki; Edward A. ;   et al. | 2018-07-12 |
Spirocyclic Hat Inhibitors And Methods For Their Use App 20180071262 - Kesicki; Edward A. ;   et al. | 2018-03-15 |
Pyridopyrimidinone inhibitors of kinases Grant 9,718,821 - Woods , et al. August 1, 2 | 2017-08-01 |
Pyridine CDK9 kinase inhibitors Grant 9,650,358 - Mastracchio , et al. May 16, 2 | 2017-05-16 |
Spirocyclic Hat Inhibitors And Methods For Their Use App 20160235716 - Kesicki; Edward A. ;   et al. | 2016-08-18 |
Substituted pyrrolo[2,3-d]pyrimindines as CDK9 kinase inhibitors Grant 9,346,813 - Florjancic , et al. May 24, 2 | 2016-05-24 |
Inhibitors of poly(ADP-ribose)polymerase Grant 9,283,222 - Gandhi , et al. March 15, 2 | 2016-03-15 |
Pyrrolopyridine inhibitors of kinases Grant 9,181,246 - Penning , et al. November 10, 2 | 2015-11-10 |
Pyridopyrimidinone inhibitors of kinases Grant 9,181,239 - Mastracchio , et al. November 10, 2 | 2015-11-10 |
5-substituted indazoles as kinase inhibitors Grant 9,163,007 - Akritopoulou-Zanze , et al. October 20, 2 | 2015-10-20 |
Pyrrolo[2,3-B]pyridine CDK9 kinase inhibitors Grant 9,073,922 - Gong , et al. July 7, 2 | 2015-07-07 |
Pyridazino[4,5-D]pyrimidin-5(6H)-one inhibitors of kinases Grant 9,051,327 - Zhu , et al. June 9, 2 | 2015-06-09 |
CDK9 kinase inhibitors Grant 8,969,375 - Lai , et al. March 3, 2 | 2015-03-03 |
Pyrrolopyridine Inhibitors Of Kinases App 20140357616 - Penning; Thomas D. ;   et al. | 2014-12-04 |
5-substituted Indazoles As Kinase Inhibitors App 20140343066 - Akritopoulou-Zanze; Irini ;   et al. | 2014-11-20 |
Picolinamide inhibitors of kinases Grant 8,859,546 - Vasudevan , et al. October 14, 2 | 2014-10-14 |
1h-benzimidazole-4-carboxamides Substituted With Phenyl At The 2-position Are Potent Parp Inhibitors App 20140296235 - Penning; Thomas D. ;   et al. | 2014-10-02 |
Pyridazino[4,5-d]pyrimidin-5(6h)-one Inhibitors Of Kinases App 20140296220 - Zhu; Gui-Dong ;   et al. | 2014-10-02 |
Pyridine Cdk9 Kinase Inhibitors App 20140275011 - Mastracchio; Anthony ;   et al. | 2014-09-18 |
Pyrrolopyrimindine Cdk9 Kinase Inhibitors App 20140275004 - Florjancic; Alan S. ;   et al. | 2014-09-18 |
Cdk9 Kinase Inhibitors App 20140275153 - Lai; Chunqiu ;   et al. | 2014-09-18 |
Pyrrolo[2,3-b]pyridine Cdk9 Kinase Inhibitors App 20140275027 - Gong; Jianchun ;   et al. | 2014-09-18 |
Pyrrolopyridine inhibitors of kinases Grant 8,822,446 - Penning , et al. September 2, 2 | 2014-09-02 |
Pyridazino[4,5-D]pyrimidin-5(6H)-one inhibitors of kinases Grant 8,796,289 - Zhu , et al. August 5, 2 | 2014-08-05 |
Inhibitors Of Poly(adp-ribose)polymerase App 20140212509 - Gandhi; Virajkumar B. ;   et al. | 2014-07-31 |
Pyrazoloquinolones Are Potent Parp Inhibitors App 20140213610 - Penning; Thomas D. ;   et al. | 2014-07-31 |
Chemical entities to be used for Wee1 inhibition for the treatment of cancer Grant 8,716,297 - Woods , et al. May 6, 2 | 2014-05-06 |
Tricyclic inhibitors of kinases Grant 8,710,065 - Tong , et al. April 29, 2 | 2014-04-29 |
1H-benzimidazole-4-carboxamides substituted with phenyl at the 2-position are potent PARP inhibitors Grant 8,697,736 - Penning , et al. April 15, 2 | 2014-04-15 |
5-substituted indazoles as kinase inhibitors Grant 8,648,069 - Akritopoulou-Zanze , et al. February 11, 2 | 2014-02-11 |
Pyrazoloquinolones are potent PARP inhibitors Grant 8,546,368 - Penning , et al. October 1, 2 | 2013-10-01 |
Pyridopyrimidinone Inhibitors Of Kinases App 20130225589 - Woods; Keith W. ;   et al. | 2013-08-29 |
Inhibitors of poly(ADP-ribose)polymerase Grant 8,466,150 - Gandhi , et al. June 18, 2 | 2013-06-18 |
Pyrrolopyrazinone inhibitors of kinases Grant 8,450,320 - Zhu , et al. May 28, 2 | 2013-05-28 |
Pyrrolopyridine inhibitors of kinases Grant 8,435,980 - Florjancic , et al. May 7, 2 | 2013-05-07 |
Pyridopyrimidinone Inhibitors Of Kinases App 20130102590 - Mastracchio; Anthony ;   et al. | 2013-04-25 |
Pyrrolopyrazine inhibitors of kinases Grant 8,383,624 - Penning , et al. February 26, 2 | 2013-02-26 |
Phthalazin-(2H)-one inhibitors of kinases Grant 8,383,623 - Zhu , et al. February 26, 2 | 2013-02-26 |
Pyridazino[4,5-d]pyrimidin-5(6h)-one Inhibitors Of Kinases App 20130023523 - Zhu; Gui-Dong ;   et al. | 2013-01-24 |
New Chemical Entities To Be Used For Wee1 Inhibition For The Treatment Of Cancer App 20130018045 - Woods; Keith W. ;   et al. | 2013-01-17 |
Parp Inhibitors For The Treatment Of Cipn App 20120258180 - Giranda; Vincent Louis ;   et al. | 2012-10-11 |
Tricyclic Inhibitors Of Kinases App 20120220572 - Tong; Yunsong ;   et al. | 2012-08-30 |
Picolinamide Inhibitors Of Kinases App 20120190681 - Vasudevan; Anil ;   et al. | 2012-07-26 |
2-substituted-1H-benzimidazole-4-carboxamides are PARP inhibitors Grant 8,217,070 - Zhu , et al. July 10, 2 | 2012-07-10 |
Potent PARP inhibitors Grant 8,183,250 - Penning , et al. May 22, 2 | 2012-05-22 |
Substituted thieno[3,2-d]pyrimidine PIM kinase inhibitors as cancer chemotherapeutics Grant 8,148,384 - Penning , et al. April 3, 2 | 2012-04-03 |
Poly(ADP-ribose)polymerase inhibitors Grant 8,143,284 - Gandhi , et al. March 27, 2 | 2012-03-27 |
Combination Therapy With Parp Inhibitors App 20120045524 - Wernet; Wolfgang ;   et al. | 2012-02-23 |
Benzimidazole Poly(adp Ribose)polymerase Inhibitors App 20120046303 - Gandhi; Virajkumar B. ;   et al. | 2012-02-23 |
Benzthiazole inhibitors of poly(ADP-ribose)polymerase Grant 8,093,396 - Przytulinska , et al. January 10, 2 | 2012-01-10 |
Benzoxazole Inhibitors Of Poly(adp-ribose)polymerase App 20110293744 - Przytulinska; Magdalena K. ;   et al. | 2011-12-01 |
Benzimidazole poly(ADP ribose)polymerase inhibitors Grant 8,067,613 - Gandhi , et al. November 29, 2 | 2011-11-29 |
Pyrrolopyrazinone Inhibitors Of Kinases App 20110257189 - Zhu; Gui-Dong ;   et al. | 2011-10-20 |
Pyrrolopyridine Inhibitors Of Kinases App 20110257152 - Penning; Thomas D. ;   et al. | 2011-10-20 |
Phthalazin-(2h)-one Inhibitors Of Kinases App 20110257187 - Zhu; Gui-Dong ;   et al. | 2011-10-20 |
Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors Grant 7,999,117 - Giranda , et al. August 16, 2 | 2011-08-16 |
Combination Therapy With Parp Inhibitors App 20110151023 - Wernet; Wolfgang ;   et al. | 2011-06-23 |
Combination Therapy With Parp Inhibitors App 20110152336 - Wernet; Wolfgang ;   et al. | 2011-06-23 |
Cyclobut-3-ene-1,2,-dione inhibitors of polo-like kinases Grant 7,956,185 - Diebold , et al. June 7, 2 | 2011-06-07 |
Pyrrolopyridine Inhibitors Of Kinases App 20110015173 - Florjancic; Alan S. ;   et al. | 2011-01-20 |
Pyrrolopyrazine Inhibitors Of Kinases App 20110015172 - Penning; Thomas D. ;   et al. | 2011-01-20 |
2-substituted-1h-benzimidazole-4-carboxamides Are Parp Inhibitors App 20100234425 - Zhu; Gui-Dong ;   et al. | 2010-09-16 |
Pyrroloquinoxalinone inhibitors of poly(ADP-ribose)polymerase Grant 7,790,721 - Giranda , et al. September 7, 2 | 2010-09-07 |
Benzthiazole Inhibitors Of Poly(adp-ribose)polymerase App 20100183743 - Przytulinska; Magdalena K. ;   et al. | 2010-07-22 |
2-substituted-1 h-benzimidazile-4-carboxamides are PARP inhibitors Grant 7,728,026 - Zhu , et al. June 1, 2 | 2010-06-01 |
Potent Parp Inhibitors App 20090298858 - Penning; Thomas D. ;   et al. | 2009-12-03 |
Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors Grant 7,595,406 - Penning , et al. September 29, 2 | 2009-09-29 |
5-substituted Indazoles As Kinase Inhibitors App 20090203690 - Akritopoulou-Zanze; Irini ;   et al. | 2009-08-13 |
Substituted 1h-benzimidazole-4-carboxamides Are Potent Parp Inhibitors App 20090186877 - Giranda; Vincent L. ;   et al. | 2009-07-23 |
1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors Grant 7,550,603 - Zhu , et al. June 23, 2 | 2009-06-23 |
Benzimidazole Poly(adp Ribose)polymerase Inhibitors App 20090030016 - Gandhi; Virajkumar B. ;   et al. | 2009-01-29 |
Pim Kinase Inhibitors As Cancer Chemotherapeutics App 20090030196 - Wang; Le ;   et al. | 2009-01-29 |
Substituted 1H-benzimidazole-4-carboxamides are potent PARP inhibitors Grant 7,462,724 - Penning , et al. December 9, 2 | 2008-12-09 |
Combination Therapy With Parp Inhibitors App 20080280867 - Giranda; Vincent L. ;   et al. | 2008-11-13 |
Inhibitors Of Poly(adp-ribose)polymerase App 20080269234 - Gandhi; Virajkumar B. ;   et al. | 2008-10-30 |
Process for preparing prodrugs of benzenesulfonamide-containing COX-2 inhibitors Grant 7,420,061 - Talley , et al. September 2, 2 | 2008-09-02 |
Inhibitors Of Poly(adp-ribose)polymerase App 20080161292 - Giranda; Vincent L. ;   et al. | 2008-07-03 |
Pim Kinase Inhibitors As Cancer Chemotherapeutics App 20080161578 - Penning; Thomas D. ;   et al. | 2008-07-03 |
Pim Kinase Inhibitors As Cancer Chemotherapeutics App 20080161559 - Penning; Thomas D. ;   et al. | 2008-07-03 |
Inhibitors Of Poly(adp-ribose)polymerase App 20080161280 - Gandhi; Virajkumar B. ;   et al. | 2008-07-03 |
Combination Therapy With Parp Inhibitors App 20080146638 - Giranda; Vincent L. ;   et al. | 2008-06-19 |
Poly(adp-ribose)polymerase Inhibitors App 20080108659 - Gandhi; Virajkumar B. ;   et al. | 2008-05-08 |
Inhibitors Of Polo-like Kinases App 20080015192 - Diebold; Robert B. ;   et al. | 2008-01-17 |
Potent PARP Inhibitors App 20080015182 - Penning; Thomas D. ;   et al. | 2008-01-17 |
Substituted 1h-benzimidazole-4-carboxamides Are Potent Parp Inhibitors App 20070270476 - Penning; Thomas D. ;   et al. | 2007-11-22 |
Combination Therapy with Parp Inhibitors App 20070265324 - Wernet; Wolfgang ;   et al. | 2007-11-15 |
Substituted 1h-benzimidazole-4-carboxamides Are Potent Parp Inhibitors App 20070259937 - Giranda; Vincent L. ;   et al. | 2007-11-08 |
Pyrazoloquinolones Are Potent Parp Inhibitors App 20070249597 - PENNING; THOMAS D. ;   et al. | 2007-10-25 |
1h-benzimidazole-4-carboxamides Substituted With Phenyl At The 2-position Are Potent Parp Inhibitors App 20070179136 - Penning; Thomas D. ;   et al. | 2007-08-02 |
Substituted 1h-benzimidazole-4-carboxamides Are Potent Parp Inhibitors App 20070112047 - Penning; Thomas D. ;   et al. | 2007-05-17 |
1H-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent PARP inhibitors App 20060229289 - Zhu; Gui-Dong ;   et al. | 2006-10-12 |
2-Substituted-1 H-benzimidazile-4-carboxamides are PARP inhibitors App 20060229351 - Zhu; Gui-Dong ;   et al. | 2006-10-12 |
Heteroarylakanoic acids as intergrin receptor antagonists Grant 7,119,098 - Nagarajan , et al. October 10, 2 | 2006-10-10 |
Thiazole compounds as integrin receptor antagonists derivatives Grant 7,115,596 - Wendt , et al. October 3, 2 | 2006-10-03 |
3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents Grant 7,030,153 - Talley , et al. April 18, 2 | 2006-04-18 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation Grant 6,951,949 - Talley , et al. October 4, 2 | 2005-10-04 |
Heteroarylalkanoic acids as integrin receptor antagonists Grant 6,933,304 - Nagarajan , et al. August 23, 2 | 2005-08-23 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflamation App 20050131050 - Talley, John J. ;   et al. | 2005-06-16 |
Lactone integrin antagonists Grant 6,906,051 - Ruminiski , et al. June 14, 2 | 2005-06-14 |
Heteroarylalkanoic acids as integrin receptor antagonists derivatives App 20050043344 - Boys, Mark L. ;   et al. | 2005-02-24 |
Process for preparing prodrugs of benzenesulfonamide-containing COX-2 inhibitors App 20050032851 - Talley, John J. ;   et al. | 2005-02-10 |
Pyrazole compounds as integrin receptor antagonists derivatives App 20050004200 - Penning, Thomas D. ;   et al. | 2005-01-06 |
Thiazole compounds as integrin receptor antagonists derivatives App 20050004189 - Wendt, John A. ;   et al. | 2005-01-06 |
Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors Grant 6,815,460 - Talley , et al. November 9, 2 | 2004-11-09 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation App 20040192930 - Talley, John J. ;   et al. | 2004-09-30 |
Lactone integrin antagonists App 20040116472 - Ruminiski, Peter ;   et al. | 2004-06-17 |
Heteroarylakanoic acids as intergrin receptor antagonists App 20040092497 - Nagarajan, Srinivasan Raj ;   et al. | 2004-05-13 |
Lactone integrin antagonists Grant 6,720,327 - Ruminski , et al. April 13, 2 | 2004-04-13 |
Process for preparing a substituted pyrazolyl benzenesulfonamide for the treatment of inflammation Grant 6,716,991 - Talley , et al. April 6, 2 | 2004-04-06 |
Gem-substituted alpha v beta 3 antagonists App 20040043994 - Khanna, Ish Kumar ;   et al. | 2004-03-04 |
Hydroxy acid integrin antagonists App 20040024062 - Rogers, Thomas ;   et al. | 2004-02-05 |
Lactone integrin antagonists App 20040019206 - Ruminiski, Peter ;   et al. | 2004-01-29 |
3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents App 20030153602 - Talley, John J. ;   et al. | 2003-08-14 |
3,4-diaryl thiopenes and analogs thereof having use as antiinflammatory agents Grant 6,599,934 - Talley , et al. July 29, 2 | 2003-07-29 |
Process for preparing prodrugs of benzenesulfonamide-containing cox-2 inhibitors App 20030069287 - Talley, John J. ;   et al. | 2003-04-10 |
3,4-diaryl thiophenes and analogs thereof having use as anti-inflammatory agents App 20030013744 - Talley, John J. ;   et al. | 2003-01-16 |
Heteroarylalkanoic acids as integrin receptor antagonists App 20020133023 - Nagarajan, Srinivasan Raj ;   et al. | 2002-09-19 |
Hydroxy acid integrin antagonists App 20020072500 - Rogers, Thomas ;   et al. | 2002-06-13 |
3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents App 20020058691 - TALLEY, JOHN J. ;   et al. | 2002-05-16 |
Lactone integrin antagonists App 20020045645 - Ruminiski, Peter ;   et al. | 2002-04-18 |
Para-substituted phenylene derivatives Grant 5,952,381 - Chen , et al. September 14, 1 | 1999-09-14 |
Prodrugs of benzenesulfonamide-containing COX-2 inhibitors Grant 5,932,598 - Talley , et al. August 3, 1 | 1999-08-03 |
1,3,5 trisubstituted pyrazole compounds for treatment of inflammation Grant 5,908,852 - Talley , et al. June 1, 1 | 1999-06-01 |
Cinnamic acid derivatives Grant 5,852,210 - Chen , et al. December 22, 1 | 1998-12-22 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation Grant 5,760,068 - Talley , et al. June 2, 1 | 1998-06-02 |
Substituted pyrazolyl benzenesulfonamides for the treatment of gastrointestinal conditions Grant 5,753,688 - Talley , et al. May 19, 1 | 1998-05-19 |
Substituted thiazoles for the treatment of inflammation Grant 5,668,161 - Talley , et al. September 16, 1 | 1997-09-16 |
LTA.sub.4 Hydrolase inhibitors Grant 5,585,492 - December 17, 1 | 1996-12-17 |
Substituted pyrazoles for the treatment of inflammation Grant 5,580,985 - Lee , et al. December 3, 1 | 1996-12-03 |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation Grant 5,563,165 - Talley , et al. October 8, 1 | 1996-10-08 |
Substituted pyrazolyl benzenesulfonamide compounds for the treatment of inflammation Grant 5,508,426 - Talley , et al. April 16, 1 | 1996-04-16 |
3,4-substituted pyrazoles for the treatment of inflammation Grant 5,486,534 - Lee , et al. January 23, 1 | 1996-01-23 |
Substituted pyrazolyl benzenesulfonamides Grant 5,466,823 - Talley , et al. November 14, 1 | 1995-11-14 |
Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof Grant 5,212,198 - Djuric , et al. May 18, 1 | 1993-05-18 |
Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof Grant 5,073,562 - Djuric , et al. December 17, 1 | 1991-12-17 |
Alkoxy-substituted dihydrobenzopyran-2-carboxylic acids and derivatives thereof, compositions and use Grant 5,051,438 - Djuric , et al. Sept | 1991-09-24 |
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