Patent | Date |
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Recombinant antibodies and immunoconjugates targeted to CD-22 bearing cells and tumors Grant 9,592,304 - FitzGerald , et al. March 14, 2 | 2017-03-14 |
Methods of Treating Pediatric Acute Lymphoblastic Leukemia with an Anti-CD22 Immunotoxin App 20150218286 - WAYNE; Alan S. ;   et al. | 2015-08-06 |
Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells Grant 8,809,502 - Pastan , et al. August 19, 2 | 2014-08-19 |
Immunogenic epitopes of NGEP antigen Grant 8,748,390 - Schlom , et al. June 10, 2 | 2014-06-10 |
Blocking mesothelin peptide fragments Grant 8,623,828 - Ho , et al. January 7, 2 | 2014-01-07 |
Anti-mesothelin antibodies Grant 8,460,660 - Ho , et al. June 11, 2 | 2013-06-11 |
Methods of Treating Pediatric Acute Lymphoblastic Leukemia with an Anti-CD22 Immunotoxin App 20120177567 - WAYNE; Alan S. ;   et al. | 2012-07-12 |
Anti-mesothelin Antibodies App 20120107933 - Ho; Mitchell ;   et al. | 2012-05-03 |
Immunogenic Epitopes Of Ngep Antigen App 20120052116 - Schlom; Jeffrey ;   et al. | 2012-03-01 |
Immunogenic peptides for the treatment of prostate and breast cancer Grant 8,043,623 - Berzofsky , et al. October 25, 2 | 2011-10-25 |
Blocking Mesothelin Peptide Fragments App 20110236385 - Ho; Mitchell ;   et al. | 2011-09-29 |
IRTA2 antibodies and methods of use Grant 7,999,077 - Pastan , et al. August 16, 2 | 2011-08-16 |
Mutated Anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells Grant 7,777,019 - Pastan , et al. August 17, 2 | 2010-08-17 |
Recombinant Antibodies And Immunoconjugates Targeted To Cd-22 Bearing Cells And Tumors App 20090305411 - FitzGerald; David J. ;   et al. | 2009-12-10 |
Gene Expressed In Prostate Cancer And Methods Of Use App 20090304702 - Pastan; Ira ;   et al. | 2009-12-10 |
Mesothelin, A Differentiation Antigen Present On Mesothelium, Mesotheliomas, and Ovarian Cancers and Methods and Kits for Targeting the Antigen App 20090280556 - Pastan; Ira ;   et al. | 2009-11-12 |
Immunogenic Peptides For The Treatment Of Prostate And Breast Cancer App 20090208518 - Berzofsky; Jay A. ;   et al. | 2009-08-20 |
Gene expressed in prostate cancer, methods and use thereof Grant 7,572,887 - Pastan , et al. August 11, 2 | 2009-08-11 |
Immunogenic peptides for the treatment of prostate and breast cancer Grant 7,541,035 - Berzofsky , et al. June 2, 2 | 2009-06-02 |
Recombinant antibodies and immunoconjugates targeted to CD-22 bearing cells and tumors Grant 7,541,034 - Fitzgerald , et al. June 2, 2 | 2009-06-02 |
Irta2 Antibodies and Methods of Use App 20080292632 - Pastan; Ira ;   et al. | 2008-11-27 |
Lambda phage display system and the process Grant 7,410,801 - Chaudhary , et al. August 12, 2 | 2008-08-12 |
Page-4, an x-linked gage-like gene expressed in normal and neoplastic prostate, testis and uterus, and uses therefor Grant 7,399,827 - Pastan , et al. July 15, 2 | 2008-07-15 |
Mesothelin, immunogenic peptides derived therefrom, and compositions comprising mesothelin, or immunogenic peptides thereof Grant 7,375,183 - Pastan , et al. May 20, 2 | 2008-05-20 |
Anti-EGFRvIII scFvs with improved cytotoxicity and yield, immunotoxins based thereon, and methods of use thereof Grant 7,129,332 - Pastan , et al. October 31, 2 | 2006-10-31 |
Gene expressed in prostate cancer, methods and use thereof App 20060194204 - Pastan; Ira ;   et al. | 2006-08-31 |
Anti-mesothelin antibodies having high binding affinity Grant 7,081,518 - Pastan , et al. July 25, 2 | 2006-07-25 |
Immunogenic peptides for the treatment of prostate and breast cancer App 20060140967 - Berzofsky; Jay A. ;   et al. | 2006-06-29 |
T-cell receptor.gamma. alternate reading frame protein, (TARP) and uses thereof Grant 7,052,703 - Pastan , et al. May 30, 2 | 2006-05-30 |
Pharmaceutical composition for treatment of drug dependence App 20060058336 - Nakanishi; Shigetada ;   et al. | 2006-03-16 |
Recombinant immunotoxin and use in treating tumors App 20060051359 - Pastan; Ira ;   et al. | 2006-03-09 |
Novel lambda phage display system and the process App 20050181494 - Chaudhary, Vijay Kumar ;   et al. | 2005-08-18 |
Xage-1, a gene expressed in multiple cancers, and uses thereof App 20040087772 - Pastan, Ira ;   et al. | 2004-05-06 |
Pegylation of linkers improves antitumor activity and reduces toxicity of immunoconjugates App 20040018203 - Pastan, Ira ;   et al. | 2004-01-29 |
Anti-egfrvIII scfvs with improved cytotoxicity and yield, immunotoxins based thereon, and methods of use thereof App 20030211097 - Pastan, Ira ;   et al. | 2003-11-13 |
IL-13 receptor specific chimeric proteins & uses thereof App 20030129132 - Puri, Raj K. ;   et al. | 2003-07-10 |
IL-13 receptor specific chimeric proteins and uses thereof Grant 6,518,061 - Puri , et al. February 11, 2 | 2003-02-11 |
Protease-activatable pseudomonas exotoxin A-like proproteins Grant 6,426,075 - Fitzgerald , et al. July 30, 2 | 2002-07-30 |
Polynucleotides encoding protease-activatable pseudomonas exotoxin a-like proproteins Grant 6,423,513 - Fitzgerald , et al. July 23, 2 | 2002-07-23 |
Nucleic acid encoding mesothelin, a differentiation antigen present on mesothelium, mesotheliomas and ovarian cancers Grant 6,153,430 - Pastan , et al. November 28, 2 | 2000-11-28 |
Recombinant immunotoxin composed of a single chain antibody reacting with the human transferrin receptor and diptheria toxin Grant 6,099,842 - Pastan , et al. August 8, 2 | 2000-08-08 |
Mesothelium antigen and methods and kits for targeting it Grant 6,083,502 - Pastan , et al. July 4, 2 | 2000-07-04 |
Nucleic acids encoding immunotoxins containing a disulfide-stabilized antibody fragment replacing half or more of domain IB of pseudomonas exotoxin, and methods of use of the encoded immunotoxins Grant 6,074,644 - Pastan , et al. June 13, 2 | 2000-06-13 |
Circularly permuted ligands and circularly permuted chimeric molecules Grant 6,011,002 - Pastan , et al. January 4, 2 | 2000-01-04 |
Single chain B3 antibody fusion proteins and their uses Grant 5,990,296 - Pastan , et al. November 23, 1 | 1999-11-23 |
Immunotoxin containing a disulfide-stabilized antibody fragment joined to a Pseudomonas exotoxin that does not require proteolytic activation Grant 5,980,895 - Pastan , et al. November 9, 1 | 1999-11-09 |
Methods of inducing multidrug resistance using human MDR1 cDNA Grant 5,928,637 - Gottesman , et al. July 27, 1 | 1999-07-27 |
IL-13 receptor specific chimeric proteins Grant 5,919,456 - Puri , et al. July 6, 1 | 1999-07-06 |
Humanized B3 antibody fragments, fusion proteins, and uses thereof Grant 5,889,157 - Pastan , et al. March 30, 1 | 1999-03-30 |
Vectors carrying MDR1 cDNA which confer multidrug resistance on transduced cells Grant 5,851,819 - Gottesman , et al. December 22, 1 | 1998-12-22 |
Transgenic animals expressing a multidrug resistance cDNA Grant 5,849,998 - Gottesman , et al. December 15, 1 | 1998-12-15 |
Monoclonal antibodies and conjugates thereof useful for the treatment of cancer Grant 5,817,313 - Willingham , et al. October 6, 1 | 1998-10-06 |
Cellular apoptosis susceptibility protein (CSP) and antisense CSP Grant 5,759,782 - Pastan , et al. June 2, 1 | 1998-06-02 |
Target-specific, cytotoxic, recombinant pseudomonas exotoxin Grant 5,705,163 - Pastan , et al. January 6, 1 | 1998-01-06 |
IL-13 receptor specific chimeric proteins and uses thereof Grant 5,614,191 - Puri , et al. March 25, 1 | 1997-03-25 |
Single chain B3 antibody fusion proteins and their uses Grant 5,608,039 - Pastan , et al. March 4, 1 | 1997-03-04 |
Cytotoxic agent against specific virus infection Grant 5,587,455 - Berger , et al. December 24, 1 | 1996-12-24 |
Monoclonal antibody binding cell surface antigens for diagnosing cancer Grant 5,525,337 - Willingham , et al. June 11, 1 | 1996-06-11 |
Pseudomonas exotoxins (PE) and conjugates thereof having lower animal toxicity with high cytocidal activity through substitution of positively charged amino acids Grant 5,512,658 - Pastan , et al. April 30, 1 | 1996-04-30 |
Monoclonal antibody useful for the diagnosis of cancer Grant 5,320,956 - Willingham , et al. June 14, 1 | 1994-06-14 |
Mouse monoclonal antibodies specific for normal primate tissue, malignant human cultural cell lines human tumors Grant 5,242,813 - Pastan , et al. September 7, 1 | 1993-09-07 |
CD-4/cytotoxic gene fusions Grant 5,206,353 - Berger , et al. April 27, 1 | 1993-04-27 |
Gene therapy using gene fusions for genetic or acquired disorders Grant 5,166,059 - Pastan , et al. November 24, 1 | 1992-11-24 |
Selectively cytotoxic IL-4-PE40 fusion protein Grant 5,082,927 - Pastan , et al. January 21, 1 | 1992-01-21 |
Monoclonal antibody against ovarian cancer cells (OVB-3) Grant 4,806,494 - Pastan , et al. February 21, 1 | 1989-02-21 |
Pseudomonas exotoxin conjugate immunotoxins Grant 4,545,985 - Pastan , et al. October 8, 1 | 1985-10-08 |