Patent | Date |
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Methods And Compositions For Increasing N-acetylglucosaminidase Activity In The Cns App 20220127369 - PARDRIDGE; William M. ;   et al. | 2022-04-28 |
Methods And Compositions For Increasing Galactosidase Beta-1 Activity In The Cns App 20210403584 - PARDRIDGE; William M. ;   et al. | 2021-12-30 |
Macromolecular compositions that cross the blood-brain barrier and methods of use thereof Grant 11,155,631 - Pardridge , et al. October 26, 2 | 2021-10-26 |
Methods And Compositions For Increasing Iduronate 2-sulfatase Activity In The Cns App 20210253681 - PARDRIDGE; William M. ;   et al. | 2021-08-19 |
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant 11,028,156 - Pardridge , et al. June 8, 2 | 2021-06-08 |
Compositions and methods related to structures that cross the blood brain barrier Grant 10,906,981 - Pardridge , et al. February 2, 2 | 2021-02-02 |
Methods And Compositions For Increasing N-acetylglucosaminidase Activity In The Cns App 20210002379 - PARDRIDGE; William M. ;   et al. | 2021-01-07 |
Methods And Compositions For Increasing Enzyme Activity In The Cns App 20200308292 - PARDRIDGE; William M. ;   et al. | 2020-10-01 |
Fusion Proteins For Delivery Of Gdnf To The Cns App 20200254113 - Kind Code | 2020-08-13 |
Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU Grant 10,538,589 - Pardridge , et al. Ja | 2020-01-21 |
Methods And Compositions For Increasing Alpha-l-iduronidase Activity In The Cns App 20190389975 - Pardridge; William M. ;   et al. | 2019-12-26 |
Methods And Compositions For Increasing Iduronate 2-sulfatase Activity In The Cns App 20190185551 - Pardridge; William M. ;   et al. | 2019-06-20 |
Methods and compositions for increasing .alpha.-L-iduronidase activity in the CNS Grant 10,202,467 - Pardridge , et al. Feb | 2019-02-12 |
Macromolecular compositions that cross the blood-brain barrier and methods of use thereof Grant 10,144,783 - Pardridge , et al. De | 2018-12-04 |
Methods And Compositions For Increasing Iduronate 2-sulfatase Activity In The Cns App 20180251535 - Pardridge; William M. ;   et al. | 2018-09-06 |
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant 10,011,651 - Pardridge , et al. July 3, 2 | 2018-07-03 |
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant 9,975,955 - Pardridge , et al. May 22, 2 | 2018-05-22 |
Methods And Compositions For Increasing Alpha-l-iduronidase Activity In The Cns App 20170114152 - Pardridge; William M. ;   et al. | 2017-04-27 |
Methods and compositions for increasing .alpha.-L-iduronidase activity in the CNS Grant 9,567,400 - Pardridge , et al. February 14, 2 | 2017-02-14 |
Compositions and methods for blood-brain barrier delivery of IgG-decoy receptor fusion proteins Grant 9,533,055 - Pardridge , et al. January 3, 2 | 2017-01-03 |
Methods And Compositions For Increasing N-acetylglucosaminidase Activity In The Cns App 20160208006 - Pardridge; William M. ;   et al. | 2016-07-21 |
Compositions And Methods Related To Structures That Cross The Blood Brain Barrier App 20160152719 - Pardridge; William M. ;   et al. | 2016-06-02 |
Methods And Compositions For Increasing Alpha-l-iduronidase Activity In The Cns App 20150299328 - Pardridge; William M. ;   et al. | 2015-10-22 |
Macromolecular Compositions That Cross The Blood-brain Barrier And Methods Of Use Thereof App 20150203586 - PARDRIDGE; William M. ;   et al. | 2015-07-23 |
Methods and compositions for increasing .alpha.-L-iduronidase activity in the CNS Grant 8,974,791 - Pardridge , et al. March 10, 2 | 2015-03-10 |
Methods And Compositions For Increasing Arylsulfatase A Activity In The Cns App 20150064184 - PARDRIDGE; William M. ;   et al. | 2015-03-05 |
Methods And Compositions For Increasing Enzyme Activity In The Cns App 20150023956 - PARDRIDGE; William M. ;   et al. | 2015-01-22 |
Methods And Compositions For Increasing Iduronate 2-sulfatase Activity In The Cns App 20150004160 - Pardridge; William M. ;   et al. | 2015-01-01 |
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant 08920801 - | 2014-12-30 |
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant 8,920,801 - Pardridge , et al. December 30, 2 | 2014-12-30 |
Delivery of pharmaceutical agents via the human insulin receptor Grant 8,858,950 - Pardridge , et al. October 14, 2 | 2014-10-14 |
Methods And Compositions For Increasing Arylsulfatase A Activity In The Cns App 20140294822 - PARDRIDGE; William M. ;   et al. | 2014-10-02 |
Macromolecular Compositions That Cross The Blood-brain Barrier And Methods Of Use Thereof App 20140288273 - PARDRIDGE; William M. ;   et al. | 2014-09-25 |
Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS Grant 8,834,874 - Pardridge , et al. September 16, 2 | 2014-09-16 |
Fusion Proteins For Delivery Of Gdnf To The Cns App 20140193409 - PARDRIDGE; William M. ;   et al. | 2014-07-10 |
Genetically encoded multifunctional compositions bidirectionally transported between peripheral blood and the cns Grant 8,759,297 - Pardridge , et al. June 24, 2 | 2014-06-24 |
Methods for diagnosing CNS disorders with fusion antibodies that cross the blood-brain barrier in both directions Grant 8,753,610 - Pardridge , et al. June 17, 2 | 2014-06-17 |
Fusion proteins for delivery of GDNF to the CNS Grant 8,741,260 - Pardridge , et al. June 3, 2 | 2014-06-03 |
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant 8,715,661 - Pardridge , et al. May 6, 2 | 2014-05-06 |
Methods and Compositions for Increasing Arylsulfatase A Activity in the CNS App 20130287773 - PARDRIDGE; William M. ;   et al. | 2013-10-31 |
Methods for diagnosing and treating CNS disorders by trans-blood-brain barrier delivery of protein compositions Grant 8,497,246 - Pardridge , et al. July 30, 2 | 2013-07-30 |
Methods and compositions for increasing arylsulfatase A activity in the CNS Grant 8,486,399 - Pardridge , et al. July 16, 2 | 2013-07-16 |
Methods and Compositions for Increasing Arylsulfatase A Activity in the CNS App 20130142794 - Pardridge; William M. ;   et al. | 2013-06-06 |
COMPOSITIONS AND METHODS FOR BLOOD-BRAIN BARRIER DELIVERY OF lgG-DECOY RECEPTOR FUSION PROTEINS App 20120269807 - Pardridge; William M. ;   et al. | 2012-10-25 |
Fusion proteins for blood-brain barrier delivery Grant 8,142,781 - Pardridge , et al. March 27, 2 | 2012-03-27 |
Fusion proteins for delivery of erythropoietin to the CNS Grant 8,124,095 - Pardridge , et al. February 28, 2 | 2012-02-28 |
Nucleic acids encoding and methods of producing fusion proteins Grant 8,053,569 - Pardridge , et al. November 8, 2 | 2011-11-08 |
Methods and Compositions for Increasing Iduronate 2-Sulfatase Activity in the CNS App 20110110935 - Pardridge; William M. ;   et al. | 2011-05-12 |
Macromolecular Compositions That Cross The Blood-brain Barrier And Methods Of Use Thereof App 20100290985 - Pardridge; William M. ;   et al. | 2010-11-18 |
Fusion Proteins For Delivery Of Erythropoietin To The Cns App 20100261647 - Pardridge; William M. ;   et al. | 2010-10-14 |
Fusion antibodies that cross the blood-brain barrier in both directions Grant 7,741,446 - Pardridge , et al. June 22, 2 | 2010-06-22 |
Compositions And Methods For Blood-brain Barrier Delivery Of Organophosphatases App 20100098693 - Pardridge; William M. ;   et al. | 2010-04-22 |
Compositions And Methods For Blood-brain Barrier Delivery In The Mouse App 20100077498 - Pardridge; William M. ;   et al. | 2010-03-25 |
Fusion Proteins For Delivery Of Gdnf To The Cns App 20090156498 - Pardridge; William M. ;   et al. | 2009-06-18 |
Delivery of pharmaceutical agents via the human insulin receptor App 20090068206 - Pardridge; William M. ;   et al. | 2009-03-12 |
Methods And Compositions For Increasing Alpha-l-iduronidase Activity In The Cns App 20090053219 - Pardridge; William M. ;   et al. | 2009-02-26 |
Macromolecular Compositions that Cross the Blood-Brain Barrier and Methods of Use Thereof App 20080170994 - Pardridge; William M. ;   et al. | 2008-07-17 |
Methods for Diagnosing and Treating CNS Disorders by Trans-Blood-Brain Barrier Delivery of Protein Compositions App 20080171055 - Pardridge; William M. ;   et al. | 2008-07-17 |
Genetically Encoded Multifunctional Compositions Bidrectionally Transported Between Peripheral Blood and the CNS App 20080152645 - Pardridge; William M. ;   et al. | 2008-06-26 |
Transport of basic fibroblast growth factor across the blood brain barrier App 20080154022 - Wu; Dafang ;   et al. | 2008-06-26 |
Delivery of pharmaceutical agents via the human insulin receptor Grant 7,388,079 - Pardridge , et al. June 17, 2 | 2008-06-17 |
Delivery of pharmaceutical agents via the human insulin receptor App 20080051564 - Pardridge; William M. ;   et al. | 2008-02-28 |
Nucleic acids encoding and methods of producing fusion proteins App 20070082380 - Pardridge; William M. ;   et al. | 2007-04-12 |
Fusion proteins for blood-brain barrier delivery App 20070081992 - Pardridge; William M. ;   et al. | 2007-04-12 |
Non-invasive gene targeting to ocular cells Grant 7,090,864 - Pardridge August 15, 2 | 2006-08-15 |
Non-invasive gene targeting to ocular cells App 20060105982 - Pardridge; William M. | 2006-05-18 |
Delivery of genes encoding short hairpin RNA using receptor-specific nanocontainers App 20050202075 - Pardridge, William M. ;   et al. | 2005-09-15 |
Delivery of enzymes to the brain App 20050142141 - Pardridge, William M. | 2005-06-30 |
Anti-growth factor receptor avidin fusion proteins as universal vectors for drug delivery App 20050085419 - Morrison, Sherie L. ;   et al. | 2005-04-21 |
Immunonanoparticles App 20050042298 - Pardridge, William M. ;   et al. | 2005-02-24 |
Delivery of pharmaceutical agents via the human insulin receptor App 20040101904 - Pardridge, William M. ;   et al. | 2004-05-27 |
Transport of basic fibroblast growth factor across the blood brain barrier App 20040102369 - Wu, Dafang ;   et al. | 2004-05-27 |
Non-invasive gene targeting to ocular cells App 20020054902 - Pardridge, William M. | 2002-05-09 |
Non-invasive gene targeting to the brain Grant 6,372,250 - Pardridge April 16, 2 | 2002-04-16 |
Drug delivery of antisense oligonucleotides and peptides to tissues in vivo and to cells using avidin-biotin technology Grant 6,287,792 - Pardridge , et al. September 11, 2 | 2001-09-11 |
Method for enhancing antibody transport through capillary barriers Grant 5,130,129 - Pardridge * July 14, 1 | 1992-07-14 |
Cationized antibodies for delivery through the blood-brain barrier Grant 5,004,697 - Pardridge April 2, 1 | 1991-04-02 |
Capillary depletion method for quantifying transcytosis through the blood-brain barrier Grant 4,992,255 - Pardridge February 12, 1 | 1991-02-12 |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier Grant 4,902,505 - Pardridge , et al. February 20, 1 | 1990-02-20 |
Chimeric peptides for neuropeptide delivery through the blood-brain barrier Grant 4,801,575 - Pardridge January 31, 1 | 1989-01-31 |