Patent | Date |
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Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137 Grant 7,138,374 - Springer , et al. November 21, 2 | 2006-11-21 |
High throughput method for functionally classifying proteins identified using a genomics approach Grant 7,122,321 - Pantoliano , et al. October 17, 2 | 2006-10-17 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137 App 20050159350 - Springer, Barry A. ;   et al. | 2005-07-21 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization Grant 6,849,458 - Pantoliano , et al. February 1, 2 | 2005-02-01 |
Crystal structure of angiotensin-converting enzyme-related carboxypeptidase App 20040209344 - Pantoliano, Michael W. ;   et al. | 2004-10-21 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization App 20040185504 - Pantoliano, Michael W. ;   et al. | 2004-09-23 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137 Grant 6,767,722 - Springer , et al. July 27, 2 | 2004-07-27 |
Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, aspartate 101 or leucine 137 Grant 6,737,404 - Springer , et al. May 18, 2 | 2004-05-18 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization App 20030203497 - Pantoliano, Michael W. ;   et al. | 2003-10-30 |
Microplate thermal shift assay for ligand development using 5- (4"-dimethylaminophenyl) -2- (4' -phenyl) oxazole derivative fluorescent dyes App 20030175813 - Pantoliano, Michael W. ;   et al. | 2003-09-18 |
Microplate thermal shift assay for ligand development using 5-(4"dimethylaminophenyl)-2-(4'-phenyl)oxazole derivative fluorescent dyes Grant 6,569,631 - Pantoliano , et al. May 27, 2 | 2003-05-27 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization App 20020114734 - Pantoliano, Michael W. ;   et al. | 2002-08-22 |
Method for identifying lead compounds Grant 6,303,322 - Pantoliano , et al. October 16, 2 | 2001-10-16 |
Method for identifying conditions that facilitate recombinant protein folding Grant 6,291,192 - Pantoliano , et al. September 18, 2 | 2001-09-18 |
Analogs of human basic fibroblast growth factor App 20010020004 - Springer, Barry A. ;   et al. | 2001-09-06 |
Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137 Grant 6,274,712 - Springer , et al. August 14, 2 | 2001-08-14 |
Method for determining conditions that facilitate protein crystallization Grant 6,268,158 - Pantoliano , et al. July 31, 2 | 2001-07-31 |
Method for sensing and processing fluorescence data from multiple samples Grant 6,268,218 - Pantoliano , et al. July 31, 2 | 2001-07-31 |
High Throughput Method For Functionally Classifying Proteins Identified Using A Genomics Approach App 20010003648 - PANTOLIANO, MICHAEL W. ;   et al. | 2001-06-14 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization Grant 6,214,293 - Pantoliano , et al. April 10, 2 | 2001-04-10 |
Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization Grant 6,036,920 - Pantoliano , et al. March 14, 2 | 2000-03-14 |
Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization Grant 6,020,141 - Pantoliano , et al. February 1, 2 | 2000-02-01 |
Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins Grant 5,260,207 - Pantoliano , et al. November 9, 1 | 1993-11-09 |
Thermally stable serine proteases Grant 5,246,849 - Bryan , et al. September 21, 1 | 1993-09-21 |
Biosynthetic uses of thermostable proteases Grant 5,116,741 - Bryan , et al. May 26, 1 | 1992-05-26 |
Subtilisin mutations Grant 5,013,657 - Bryan , et al. May 7, 1 | 1991-05-07 |
Combining mutations for stabilization of subtilisin Grant 4,990,452 - Bryan , et al. February 5, 1 | 1991-02-05 |
Subtilisin with increased thermal stability Grant 4,980,288 - Bryan , et al. December 25, 1 | 1990-12-25 |
Computer designed stabilized proteins and method for producing same Grant 4,908,773 - Pantoliano , et al. March 13, 1 | 1990-03-13 |
Computer-based method for designing stablized proteins Grant 4,853,871 - Pantoliano , et al. August 1, 1 | 1989-08-01 |