Patent | Date |
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Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 8,465,921 - Hedgpeth , et al. June 18, 2 | 2013-06-18 |
Hybridization And Mismatch Discrimination Using Oligonucleotides Conjugated To Minor Groove Binders App 20110275070 - Hedgpeth; Joel ;   et al. | 2011-11-10 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 7,794,945 - Hedgpeth , et al. September 14, 2 | 2010-09-14 |
Oligonucleotides Containing Pyrazolo[3,4-d] Pyrimidines For Hybridization And Mismatch Discrimination App 20100228017 - Meyer, JR.; Rich B. ;   et al. | 2010-09-09 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 7,556,923 - Hedgpeth , et al. July 7, 2 | 2009-07-07 |
Hybridization And Mismatch Discrimination Using Oligonucleotides Conjugated To Minor Groove Binders App 20090048427 - HEDGPETH; JOEL ;   et al. | 2009-02-19 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 6,884,584 - Hedgpeth , et al. April 26, 2 | 2005-04-26 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 6,492,346 - Hedgpeth , et al. December 10, 2 | 2002-12-10 |
Covalently linked oligonucleotide minor groove binder conjugates Grant 6,486,308 - Kutyavin , et al. November 26, 2 | 2002-11-26 |
Oligonucleotides containing pyrazolo[3,4-d]pyrimidines for hybridization and mismatch discrimination Grant 6,485,906 - Meyer, Jr. , et al. November 26, 2 | 2002-11-26 |
Covalently linked oligonucleotide minor groove binder conjugates Grant 6,426,408 - Kutyavin , et al. July 30, 2 | 2002-07-30 |
Methods and compositions to facilitate D-loop formation by oligonucleotides Grant 6,312,925 - Meyer, Jr. , et al. November 6, 2 | 2001-11-06 |
Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders Grant 6,312,894 - Hedgpeth , et al. November 6, 2 | 2001-11-06 |
Targeted mutagenesis in living cells using modified oligonucleotides Grant 6,136,601 - Meyer, Jr. , et al. October 24, 2 | 2000-10-24 |
Oligonucleotides containing pyrazolo[3,4-D]pyrimidines for hybridization and mismatch discrimination Grant 6,127,121 - Meyer, Jr. , et al. October 3, 2 | 2000-10-03 |
Covalently linked oligonucleotide minor grove binder conjugates Grant 6,084,102 - Kutyavin , et al. July 4, 2 | 2000-07-04 |
Targeted mutagenesis in living cells using modified oligonucleotides Grant 5,935,830 - Meyer, Jr. , et al. August 10, 1 | 1999-08-10 |
Selective binding complementary oligonucleotides Grant 5,912,340 - Kutyavin , et al. June 15, 1 | 1999-06-15 |
Crosslinking oligonucleotides Grant 5,849,482 - Meyer, Jr. , et al. December 15, 1 | 1998-12-15 |
Covalently linked oligonucleotide minor grove binder conjugates Grant 5,801,155 - Kutyavin , et al. September 1, 1 | 1998-09-01 |
Oligonucleotide-cyclopropapyrroloindole conjugates as sequence specific hybridization and crosslinking agents for nucleic acids Grant 5,659,022 - Kutyavin , et al. August 19, 1 | 1997-08-19 |
Oligonucleotides containing n-methyl thiolated bases having antiviral activity Grant 5,652,359 - Meyer, Jr. , et al. July 29, 1 | 1997-07-29 |
Sterol modified oligonucleotide duplexes having anticancer activity Grant 5,646,126 - Cheng , et al. July 8, 1 | 1997-07-08 |
Peptide linkers for improved oligonucleotide delivery Grant 5,574,142 - Meyer, Jr. , et al. November 12, 1 | 1996-11-12 |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides Grant 5,512,667 - Reed , et al. April 30, 1 | 1996-04-30 |
Solid support for synthesis of 3'-tailed oligonucleotides Grant 5,419,966 - Reed , et al. May 30, 1 | 1995-05-30 |
Non toxic compositions and methods useful for the extraction of nucleic acids Grant 5,393,672 - Ness , et al. February 28, 1 | 1995-02-28 |
Oligo (.alpha.-arabinofuranosyl nucleotides) and .alpha.-arabinofuranosyl precursors thereof Grant 5,177,196 - Meyer, Jr. , et al. January 5, 1 | 1993-01-05 |
Non-corrosive compositions and methods useful for the extraction of nucleic acids Grant 5,130,423 - Van Ness , et al. July 14, 1 | 1992-07-14 |
6-Substituted purine 3',5'-cyclic nucleotides Grant 3,948,886 - Shuman , et al. April 6, 1 | 1976-04-06 |
2,6-Disubstituted purine cyclic nucleotides Grant 3,897,413 - Shuman , et al. July 29, 1 | 1975-07-29 |
Phosphoramidates Of 3',5'-cyclic Purine Nucleotides Grant 3,852,267 - Meyer, Jr. , et al. December 3, 1 | 1974-12-03 |