Patent | Date |
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Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-- 3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide Grant 9,163,005 - Manley , et al. October 20, 2 | 2015-10-20 |
Methods and Compositions for Treating Luekemia App 20150209365 - Copland; Mhairi ;   et al. | 2015-07-30 |
Crystalline Forms of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide App 20140343087 - Manley; Paul W. ;   et al. | 2014-11-20 |
N-oxides Of N-phenyl-2-pyrimidine-amine Derivatives App 20140323494 - Bornsen; Klaus O. ;   et al. | 2014-10-30 |
Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide Grant 8,829,015 - Manley , et al. September 9, 2 | 2014-09-09 |
Antiviral Activity Of Tyrosine Kinase Inhibitors Against Hepatitus C Virus App 20140127157 - Canino; Erica ;   et al. | 2014-05-08 |
Pyrimidylaminobenzamide derivatives for systemic mastocytosis Grant 8,673,930 - Alland , et al. March 18, 2 | 2014-03-18 |
Pyrimidylaminobenzamide Derivatives for Treatment of Neurofibromatosis App 20140073660 - Manley; Paul W. | 2014-03-13 |
Combination of pyrimidylaminobenzamide compounds and imatinib for treating or preventing proliferative diseases Grant 8,653,093 - Alland , et al. February 18, 2 | 2014-02-18 |
Salts of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-- 3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide App 20140038994 - MANLEY; Paul W. ;   et al. | 2014-02-06 |
Pyrimidylaminobenzamide derivatives for treatment of neurofibromatosis Grant 8,604,045 - Manley December 10, 2 | 2013-12-10 |
Salts of 4-methyl N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl- -pyrimidin-2-ylamino)-benzamide Grant 8,580,806 - Manley , et al. November 12, 2 | 2013-11-12 |
Use of Pyrimidylaminobenzamide Derivatives for the Treatment of Fibrosis App 20130267549 - BUCHDUNGER; Elisabeth ;   et al. | 2013-10-10 |
Combinations Comprising A Protein Kinase Inhibitor Being A Pyrimidylaminobenzamide Compound And A Hsp90 Inhibitor Such As 17-11g App 20130197017 - Manley; Paul W ;   et al. | 2013-08-01 |
Crystalline Forms of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide App 20130165465 - Manley; Paul W ;   et al. | 2013-06-27 |
Salts of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-- 3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide App 20130137712 - Manley; Paul W. ;   et al. | 2013-05-30 |
Pyrimidylaminobenzamide Derivatives for Treatment of Neurofibromatosis App 20130123290 - Manley; Paul W. | 2013-05-16 |
Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide Grant 8,415,363 - Manley , et al. April 9, 2 | 2013-04-09 |
Salts of 4-methyl N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl- -pyrimidin-2-ylamino)-benzamide Grant 8,389,537 - Manley , et al. March 5, 2 | 2013-03-05 |
USE OF c-Src INHIBITORS IN COMBINATION WITH A PYRIMIDYLAMINOBENZAMIDE COMPOUND FOR THE TREATMENT OF LEUKEMIA App 20130040972 - Manley; Paul W. | 2013-02-14 |
Crystalline Forms of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide App 20130023548 - MANLEY; Paul W. ;   et al. | 2013-01-24 |
Compounds And Compositions As Protein Kinase Inhibitors App 20130012476 - DING; Qiang ;   et al. | 2013-01-10 |
Compounds And Compositions As Protein Kinase Inhibitors App 20130012704 - DING; Qiang ;   et al. | 2013-01-10 |
Crystalline forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyr- idin-3-yl-pyrimidin-2-ylamino)-benzamide Grant 8,343,984 - Manley , et al. January 1, 2 | 2013-01-01 |
Methods And Compositions For Treating Luekemia App 20120329798 - Copland; Mhairi ;   et al. | 2012-12-27 |
Salts of 4-Methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-- 3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide App 20120270891 - Manley; Paul W. ;   et al. | 2012-10-25 |
Combinations Of Therapeutic Agents For Treating Cancer App 20120252811 - Burke; Gregory Peter ;   et al. | 2012-10-04 |
Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia Grant 8,268,837 - Donato , et al. September 18, 2 | 2012-09-18 |
Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity Grant 8,222,244 - Griffin , et al. July 17, 2 | 2012-07-17 |
Organic compounds Grant 8,217,045 - Manley , et al. July 10, 2 | 2012-07-10 |
Heterobicyclic Carboxamides As Inhibitors For Kinases App 20120122857 - BOLD; Guido ;   et al. | 2012-05-17 |
Salts of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-- 3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-Benzamide Grant 8,163,904 - Manley , et al. April 24, 2 | 2012-04-24 |
Heterobicyclic carboxamides as inhibitors for kinases Grant 8,133,886 - Bold , et al. March 13, 2 | 2012-03-13 |
Use of c-Src inhibitors alone or in combination with STI571 for the treatment of leukaemia Grant 8,119,649 - Donato , et al. February 21, 2 | 2012-02-21 |
Use Of Pyrimidylaminobenzamide Derivatives For The Treatment Of Disorders Mediated By The Leucine Zipper-and Sterile Alpha Motif-containing Kinase (zak) App 20120015968 - Fabbro; Doriano ;   et al. | 2012-01-19 |
4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidaz- ol-1-yl)-3-(trifluoromethyl)phenyl]-benzamide for treatment of melanoma Grant 8,093,259 - Manley , et al. January 10, 2 | 2012-01-10 |
Bicyclic Amides As Kinase Inhibitors App 20110301157 - Bold; Guido ;   et al. | 2011-12-08 |
Combinations Comprising A Protein Kinase Inhibitor Being A Pyrimidylaminobenzamide Compound And A Hsp90 Inhibitor Such As 17-aag App 20110281902 - Manley; Paul W. ;   et al. | 2011-11-17 |
Bicyclic amides as kinase inhibitors Grant 8,026,247 - Bold , et al. September 27, 2 | 2011-09-27 |
Inhibitors of tyrosine kinases Grant 7,956,053 - Breitenstein , et al. June 7, 2 | 2011-06-07 |
Use of Pyrimidylaminobenzamide Derivatives for the Treatment of Fibrosis App 20110124670 - Buchdunger; Elisabeth ;   et al. | 2011-05-26 |
Leukemia Treatment App 20110039850 - Copland; Mhairi ;   et al. | 2011-02-17 |
Cyclic diaryl ureas suitable as tyrosine kinase inhibitors Grant 7,855,215 - Bold , et al. December 21, 2 | 2010-12-21 |
Combinations Of Jak Inhibitors App 20100280003 - Cooke; Nigel Graham ;   et al. | 2010-11-04 |
Pyrimidylaminobenzamide Derivatives For The Treatment Of Neurofibromatosis App 20100234408 - MANLEY; PAUL W. | 2010-09-16 |
Pyrimidylaminobenzamide Derivatives For Systemic Mastocytosis App 20100210673 - Alland; Leila ;   et al. | 2010-08-19 |
Combination of pyrimidylaminobenzamide compounds and imatinib for treating gastrointestinal stromal tumours Grant 7,767,688 - Alland , et al. August 3, 2 | 2010-08-03 |
Combinaton Of Pyrimidylaminobenzamide Compounds And Imatinib For Treating Or Preventing Proliferative Diseases App 20100190800 - Alland; Leila ;   et al. | 2010-07-29 |
Use Of C-src Inhibitors In Combination With A Pyrimidylaminobenzamide Compound For The Treatment Of Leukemia App 20100152198 - Manley; Paul W. | 2010-06-17 |
Organic Compounds App 20100113467 - Manley; Paul W. ;   et al. | 2010-05-06 |
Pyrimidylaminobenzamide derivatives for hypereosinophilic syndrome Grant 7,666,874 - Manley , et al. February 23, 2 | 2010-02-23 |
Cyclic sulfones useful as mitochondrial sodium-calcium exchangers App 20100029626 - Bold; Guido ;   et al. | 2010-02-04 |
Inhibitors Of Tyrosine Kinases App 20100022569 - Manley; Paul W. ;   et al. | 2010-01-28 |
Combination Comprising A) A Pyrimidylaminobenzamide Compound, And B) A Thr315lle Kinase Inhibitor App 20090286803 - Manley; Paul W. | 2009-11-19 |
Combinations Comprising Bcr-abl/c-kit/pdgf-r Tk Inhibitors For Treating Cancer App 20090233905 - Burke; Gregory Peter ;   et al. | 2009-09-17 |
Inhibitors of tyrosine kinases Grant 7,569,566 - Breitenstein , et al. August 4, 2 | 2009-08-04 |
Organic Compounds App 20090156602 - Cooke; Nigel Graham ;   et al. | 2009-06-18 |
Compounds and Compositions as Protein Kinase Inhibitors App 20090137804 - Ding; Qiang ;   et al. | 2009-05-28 |
Anthranilic acid amides and their use as VEGF receptor tyrosine kinase inhibitors Grant 7,482,369 - Bold , et al. January 27, 2 | 2009-01-27 |
Pyrimidylaminobenzamide Derivatives For the Treatment of Neurofibromatosis App 20080318988 - Manley; Paul W. | 2008-12-25 |
Combination of Organic Compounds App 20080312252 - Alland; Leila ;   et al. | 2008-12-18 |
Bicyclic Amides as Kinase Inhibitors App 20080287427 - Bold; Guido ;   et al. | 2008-11-20 |
Crystalline Forms of 4-Methyl-N- [3-(4-Methyl-Imidazol-1-Yl)-5-Trifluoromethyl-Phenyl]-3- (4-Pyridin-3-Yl-Pyrimidin-2-Ylamino) -Benzamide App 20080269269 - Manley; Paul W. ;   et al. | 2008-10-30 |
Sulphonamidoaniline Derivatives Being Janus Kinase Inhibitors App 20080261973 - Capraro; Hans-Georg ;   et al. | 2008-10-23 |
Combination of Nilotinib with Farnesyl Transferase Inhibitors App 20080255171 - Manley; Paul W. | 2008-10-16 |
Pyrimidylaminobenzamide Derivatives for Hypereosinophilic Syndrome App 20080227800 - Manley; Paul W. ;   et al. | 2008-09-18 |
Organic Compounds App 20080207591 - Manley; Paul W. ;   et al. | 2008-08-28 |
Pharmaceutical Combination of Bcr-Abl and Raf Inhibitors App 20080207658 - Manley; Paul W. | 2008-08-28 |
Combination of Organic Compounds App 20080200489 - Atadja; Peter Wisdom ;   et al. | 2008-08-21 |
Salts of 4-Methyl-N-[3-(4-Methyl-Imidazol-1-Yl)-5-Trifluoromethyl-Phenyl]-- 3-(4-Pyridin-3-Yl-Pyrimidin-2-Ylamino)-Benzamide App 20080200487 - Manley; Paul W. ;   et al. | 2008-08-21 |
Combination Of Organic Compounds App 20080200486 - Lane; Heidi ;   et al. | 2008-08-21 |
Combinations Comprising a Protein Kinase Inhibitor Being a Pyrimidylaminobenzamide Compound and a Hsp90 Inhibitor Such as 17-Aag App 20080200488 - Manley; Paul W. ;   et al. | 2008-08-21 |
Pyrimidylaminobenzamide Derivatives For Sytemic Mastocytosis App 20080176879 - Alland; Leila ;   et al. | 2008-07-24 |
Use of Pyrimidylaminobenzamides for the Treatment of Diseases that Respond to Modulation of Tie-2 Kinase Activity App 20080114001 - Manley; Paul W. ;   et al. | 2008-05-15 |
Combination Of A Vegf Receptor Inhibitor Or With A Chemotherapeutic Agent App 20080085902 - Bold; Guido ;   et al. | 2008-04-10 |
Cyclic Diaryl Ureas Suitable as Tyrosine Kinase Inhibitors App 20080039440 - Bold; Guido ;   et al. | 2008-02-14 |
Phthalazine derivatives for treating inflammatory diseases Grant 7,329,660 - Bold , et al. February 12, 2 | 2008-02-12 |
Pyridine derivatives inhibiting angiogenesis and/or VEGF receptor tyrosine kinase Grant 7,323,474 - Bold , et al. January 29, 2 | 2008-01-29 |
N-phenyl-2-pyrimidine-amine derivatives Grant 7,312,216 - Buerger , et al. December 25, 2 | 2007-12-25 |
Oxazolo-and furopyrimidines and their use in medicaments against tumors Grant 7,294,633 - Bold , et al. November 13, 2 | 2007-11-13 |
Anthranilic acid amides and their use as VEGF receptor tyrosine kinase inhibitors Grant 7,091,224 - Bold , et al. August 15, 2 | 2006-08-15 |
N-phenyl-2-pyrimidine-amine derivatives Grant 7,081,532 - Buerger , et al. July 25, 2 | 2006-07-25 |
Anthranilic acid amides and pharmaceutical use thereof Grant 7,067,543 - Bold , et al. June 27, 2 | 2006-06-27 |
Phenylpyridine derivatives useful as phosphodiesterase inhibitors Grant 6,410,547 - Manley June 25, 2 | 2002-06-25 |
Phenylpyridine derivatives useful as phosphodiesterase inhibitors App 20020028831 - Manley, Paul W. | 2002-03-07 |
Phenylpyridine derivatives useful as phosphodiesterase inhibitors Grant 6,090,817 - Manley July 18, 2 | 2000-07-18 |
Substituted alkylidene imidazoles Grant 4,837,333 - Manley , et al. June 6, 1 | 1989-06-06 |
Imidazopyridine derivatives and pharmaceutical compositions Grant 4,804,658 - Manley , et al. February 14, 1 | 1989-02-14 |
Certain 1H-imidazol-1-yl-1-lower-alkanoic acid derivatives having anti-thrombotic activity Grant 4,579,862 - Manley , et al. April 1, 1 | 1986-04-01 |